ROCCO PALERMO

Ricercatore universitario

email: rocco.palermo@uniroma1.it
telefono: 06492555142
edificio: RM110 - Regina Elena Edificio B
stanza: 401

QUALIFICA ATTUALE
Ricercatore a tempo determinato (RTDB), SSD MED/04 - Patologia Generale.

DIPARTIMENTO MEDICINA MOLECOLARE

FORMAZIONE E CARRIERA
2021 - presente: Ricercatore a tempo determinato (RTDB), SSD MED/04 – Patologia Generale, Dipartimento di Medicina Molecolare, Università di Roma “La Sapienza”, Roma, Italia.
2018 - 2021: Ricercatore a tempo determinato (RTDA), SSD MED/04 – Patologia Generale, Dipartimento di Medicina Molecolare, Università di Roma “La Sapienza”, Roma, Italia.
2012 - 2018: Post doc, Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Roma, Italia.
2011 - 2012: Assegnista di ricerca, SSD MED/04 – Patologia Generale, Dipartimento di Medicina Molecolare, Università di Roma “Sapienza”, Roma, Italia.
2009 - 2011: Titolare di borsa di studio post dottorato, Dipartimento di Medicina Sperimentale, Università di Roma “Sapienza”, Roma, Italia.
2006 - 2009: Collaboratore scientifico, Dipartimento di Medicina Sperimentale e Patologia, Università degli Studi di Roma “La Sapienza”, Roma, Italia.
2003 - 2006: Dottorato di Ricerca in Biotecnologie, Università degli studi dell'Aquila, L’Aquila, Italia.
2003: Laurea in Scienze Biologiche, Università degli Studi di Roma “La Sapienza”, Roma, Italia.

PRINCIPALI LINEE DI RICERCA
1. Interazioni tra il signaling di Notch e altre pathway oncogeniche nella T-ALL;
2. Meccanismi di regolazione e ruolo di microRNAs nella leucemia;
3. Processi epigenetici e post-traduzionali che sostengono l’aberrante espressione e attività di Notch nel cancro;
4. Ruolo del Notch signaling nel controllo dell’auto-mantenimento e del differenziamento delle cellule staminali tumorali;
5. Nuove molecole di origine naturale o sintetica dotati di attività inibitoria del signaling di Notch.

ALTRO

BREVETTI
U.S. patent number 11,104,657 granted on 31 08 2021 for “Notch inhibitors for use in the treatment of T-cell acute lymphoblastic leukemia”. Invention credited to: Botta B, Ghirga F, Giulimondi F, Ingallina C, Mori M, Palermo R, Quaglio D, Screpanti I, Tottone L, Zhdanoskaya N.

CINQUE PUBBLICAZIONI SELEZIONATE
1. N. Zhdanovskaya, M. Firrincieli, S. Lazzari, E. Pace, P. Scribani Rossi, M.P. Felli, C. Talora, I. Screpanti, R. Palermo, Targeting Notch to maximize chemotherapeutic benefits: Rationale, advanced strategies, and future perspectives. Cancers 13, 5106 (2021).
2. L. Tottone, N. Zhdanovskaya, A. Carmona Pestana, M. Zampieri, F. Simeoni, S. Lazzari, V. Ruocco, M. Pelullo, P. Caiafa, M. P. Felli, S. Checquolo, D. Bellavia, C. Talora, I. Screpanti, R. Palermo, Histone Modifications Drive Aberrant Notch3 Expression/Activity and Growth in T-ALL. Frontiers in oncology 9, 198 (2019).
3. M. Mori, L. Tottone, D. Quaglio, N. Zhdanovskaya, C. Ingallina, M. Fusto, F. Ghirga, G. Peruzzi, M. E. Crestoni, F. Simeoni, F. Giulimondi, C. Talora, B. Botta, I. Screpanti, R. Palermo, Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia. Scientific reports 7, 2213 (2017).
4. V. Kumar, R. Palermo, C. Talora, A. F. Campese, S. Checquolo, D. Bellavia, L. Tottone, G. Testa, E. Miele, S. Indraccolo, A. Amadori, E. Ferretti, A. Gulino, A. Vacca, I. Screpanti, Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia. Leukemia 28, 2324-2335 (2014).
5. R. Palermo, S. Checquolo, A. Giovenco, P. Grazioli, V. Kumar, A. F. Campese, A. Giorgi, M. Napolitano, G. Canettieri, G. Ferrara, M. E. Schinina, M. Maroder, L. Frati, A. Gulino, A. Vacca, I. Screpanti, Acetylation controls Notch3 stability and function in T-cell leukemia. Oncogene 31, 3807-3817 (2012).

Produzione scientifica

11573/1676923 - 2023 - Loss of ATP2C1 function promotes trafficking and degradation of NOTCH1: Implications for Hailey-Hailey disease
Zonfrilli, A.; Truglio, F.; Simeone, A.; Pelullo, M.; Deturris, V.; Benelli, D.; Checquolo, S.; Bellavia, D.; Palermo, R.; Uccelletti, D.; Screpanti, I.; Cialfi, S.; Talora, C. - 01a Articolo in rivista
rivista: EXPERIMENTAL DERMATOLOGY (Blackwell Munksgaard:PO Box 2148, Periodicals Department, DK-1016 Copenhagen K Denmark:011 45 33 755913, EMAIL: agentservices@oxon.blackwellpublishing.com, INTERNET: http://www.blackwellmunksgaard.com, Fax: 011 45 77 333377) pp. 1-12 - issn: 0906-6705 - wos: WOS:000938040500001 (0) - scopus: 2-s2.0-85149748147 (0)

11573/1659734 - 2022 - 5FU/Oxaliplatin-induced Jagged1 cleavage counteracts apoptosis induction in colorectal cancer. A novel mechanism of intrinsic drug resistance
Pelullo, Maria; Zema, Sabrina; De Carolis, Mariangela; Cialfi, Samantha; Giuli, Maria Valeria; Palermo, Rocco; Capalbo, Carlo; Giannini, Giuseppe; Screpanti, Isabella; Checquolo, Saula; Bellavia, Diana - 01a Articolo in rivista
rivista: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. 1-10 - issn: 2234-943X - wos: WOS:000827974000001 (0) - scopus: 2-s2.0-85134211105 (0)

11573/1664088 - 2022 - Identification of a novel curcumin derivative influencing notch pathway and DNA damage as a potential therapeutic agent in T-ALL
Zhdanovskaya, Nadezda; Lazzari, Sara; Caprioglio, Diego; Firrincieli, Mariarosaria; Maioli, Chiara; Pace, Eleonora; Imperio, Daniela; Talora, Claudio; Bellavia, Diana; Checquolo, Saula; Mori, Mattia; Screpanti, Isabella; Minassi, Alberto; Palermo, Rocco - 01a Articolo in rivista
rivista: CANCERS (Basel : MDPI) pp. - - issn: 2072-6694 - wos: WOS:000897324700001 (1) - scopus: 2-s2.0-85143627645 (1)

11573/1567658 - 2021 - When viruses cross developmental pathways
Trivedi, P.; Patel, S. K.; Bellavia, D.; Messina, E.; Palermo, R.; Ceccarelli, S.; Marchese, C.; Anastasiadou, E.; Minter, L. M.; Felli, M. P. - 01g Articolo di rassegna (Review)
rivista: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-634X - wos: WOS:000685123700002 (1) - scopus: 2-s2.0-85113208731 (4)

11573/1602861 - 2021 - Targeting notch to maximize chemotherapeutic benefits: rationale, advanced strategies, and future perspectives
Zhdanovskaya, N.; Firrincieli, M.; Lazzari, S.; Pace, E.; Rossi, P. S.; Felli, M. P.; Talora, C.; Screpanti, I.; Palermo, R. - 01g Articolo di rassegna (Review)
rivista: CANCERS (Basel : MDPI) pp. - - issn: 2072-6694 - wos: WOS:000713815300001 (9) - scopus: 2-s2.0-85116745560 (9)

11573/1471145 - 2020 - Chalcones and Chalcone-mimetic Derivatives as Notch blocking agents in T-cell acute lymphoblastic leukemia
Cammarone, Silvia; Quaglio, Deborah; Zhdanovskaya, Nadezda; Screpanti, Isabella; Christodoulou, Michael S.; Passarella, Daniele; Botta, Bruno; Palermo, Rocco; Mori, Mattia; Ghirga, Francesca; Pérez, Maria-Jesús - 04f Poster
congresso: COST Action 17104 (STRATAGEM) WG2 Meeting and International Online Symposium on “Synthesis and nanodelivery strategies for new therapeutic tools against Multidrug Resistant Tumours” (Italy)
libro: COST Action 17104 (STRATAGEM) WG2 Meeting and International Online Symposium on “Synthesis and nanodelivery strategies for new therapeutic tools against Multidrug Resistant Tumours” - ()

11573/1446421 - 2020 - Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response
Giuli, Maria Valeria; Diluvio, Giulia; Giuliani, Eugenia; Franciosa, Giulia; Di Magno, Laura; Pignataro, Maria Gemma; Tottone, Luca; Nicoletti, Carmine; Besharat, Zein Mersini; Peruzzi, Giovanna; Pelullo, Maria; Palermo, Rocco; Canettieri, Gianluca; Talora, Claudio; D'amati, Giulia; Bellavia, Diana; Screpanti, Isabella; Checquolo, Saula - 01a Articolo in rivista
rivista: ONCOGENESIS (London Nature Publishing Group) pp. 1-16 - issn: 2157-9024 - wos: WOS:000579242100001 (11) - scopus: 2-s2.0-85092794807 (11)

11573/1345708 - 2019 - PLK1 targets NOTCH1 during DNA damage and mitotic progression
De Blasio, Carlo; Zonfrilli, A.; Franchitto, Matteo; Mariano, G.; Cialfi, S.; Verma, Nagendra; Checquolo, S.; Bellavia, D.; Palermo, R.; Benelli, D.; Screpanti, I.; Talora, C. - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 17941-17950 - issn: 0021-9258 - wos: WOS:000504206800020 (13) - scopus: 2-s2.0-85075566790 (12)

11573/1347680 - 2019 - Notch3 contributes to T-cell leukemia growth via regulation of the unfolding protein response
Giuliani, Eugenia; Giuli, Maria Valeria; Diluvio, Giulia; Pelullo, Maria; Palermo, Rocco; Talora, Claudio; Bellavia, Diana; Screpanti, Isabella; Checquolo, Saula - 04d Abstract in atti di convegno
congresso: The Biennial Congress of the Italian Association of cell biology and differentiation (Bologna, Italy)
libro: The Biennial Congress of the Italian Association of cell biology and differentiation - ()

11573/1310873 - 2019 - Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains CRC progression and chemoresistance
Pelullo, Maria; Nardozza, Francesca; Zema, Sabrina; Quaranta, Roberta; Nicoletti, Carmine; Besharat, Zein Mersini; Felli, Maria Pia; Cerbelli, Bruna; D’Amati, Giulia; Palermo, Rocco; Capalbo, Carlo; Talora, Claudio; Di Marcotullio, Lucia; Giannini, Giuseppe; Checquolo, Saula; Screpanti, Isabella; Bellavia, Diana - 01a Articolo in rivista
rivista: CANCER RESEARCH (Philadelphia : American Association for Cancer Research) pp. 5575-5586 - issn: 1538-7445 - wos: WOS:000494363200013 (20) - scopus: 2-s2.0-85074445960 (20)

11573/1262145 - 2019 - Chalcones and chalcone-mimetic derivatives as Notch inhibitors in a model of T-cell Acute Lymphoblastic Leukemia
Quaglio, Deborah; Zhdanovskaya, Nadezda; Tobajas, Gloria; Cuartas, Viviana; Balducci, Silvia; Christodoulou, Michael S.; Fabrizi, Giancarlo; Gargantilla, Marta; Priego, Eva-María; Carmona Pestaña, Alvaro; Passarella, Daniele; Screpanti, Isabella; Botta, Bruno; Palermo, Rocco; Mori, Mattia; Ghirga, Francesca; Pérez-Pérez, María-Jesús - 01f Lettera, Nota
rivista: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 639-643 - issn: 1948-5875 - wos: WOS:000464767700043 (21) - scopus: 2-s2.0-85064240961 (21)

11573/1261501 - 2019 - Histone Modifications Drive Aberrant Notch3 Expression/Activity and Growth in T-ALL
Tottone, Luca; Zhdanovskaya, Nadezda; Carmona Pestaña, Álvaro; Zampieri, Michele; Simeoni, Fabrizio; Lazzari, Sara; Ruocco, Valeria; Pelullo, Maria; Caiafa, Paola; Felli, Maria Pia; Checquolo, Saula; Bellavia, Diana; Talora, Claudio; Screpanti, Isabella; Palermo, Rocco - 01a Articolo in rivista
rivista: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. 1-15 - issn: 2234-943X - wos: WOS:000463425600001 (29) - scopus: 2-s2.0-85067443438 (28)

11573/1258524 - 2019 - DNA damage stress: Cui prodest?
Verma, Nagendra; Franchitto, Matteo; Zonfrilli, Azzurra; Cialfi, Samantha; Palermo, Rocco; Talora, Claudio - 01g Articolo di rassegna (Review)
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000462542300072 (12) - scopus: 2-s2.0-85062408385 (13)

11573/1130744 - 2018 - The Notch3 receptor and its intracellular signaling-dependent oncogenic mechanisms
Bellavia, Diana; Checquolo, Saula; Palermo, Rocco; Screpanti, Isabella - 02a Capitolo o Articolo
libro: Molecular Mechanisms of Notch Signaling - (978-3-319-89511-6; 978-3-319-89512-3)

11573/1088655 - 2018 - Notch signaling as a therapeutic target for acute lymphoblastic leukemia
Bellavia, Diana; Palermo, Rocco; Felli, Maria Pia; Screpanti, Isabella; Checquolo, Saula - 01g Articolo di rassegna (Review)
rivista: EXPERT OPINION ON THERAPEUTIC TARGETS (--London United Kingdom:Informa Healthcare -London : Ashley, 2002-.) pp. 331-342 - issn: 1472-8222 - wos: WOS:000430074900004 (29) - scopus: 2-s2.0-85045679979 (32)

11573/1111436 - 2018 - NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest
Diluvio, Giulia; Del Gaudio, Francesca; Giuli, Maria Valeria; Franciosa, Giulia; Giuliani, Eugenia; Palermo, Rocco; Besharat, Zein Mersini; Pignataro, Maria Gemma; Vacca, Alessandra; D'amati, Giulia; Maroder, Marella; Talora, Claudio; Capalbo, Carlo; Bellavia, Diana; Checquolo, Saula - 01a Articolo in rivista
rivista: ONCOGENESIS (London Nature Publishing Group) pp. - - issn: 2157-9024 - wos: WOS:000433997800002 (36) - scopus: 2-s2.0-85047628678 (37)

11573/1114780 - 2018 - Targeting the ER/UPR signalling in Notch3-overexpressing T-cell acute lymphoblastic leukemia.
Giuli, Mv; Diluvio, G; Giuliani, E; Bellavia, D; Palermo, R; Screpanti, I; Checquolo, S - 04d Abstract in atti di convegno
congresso: ABCD - Ph.D. meeting (Salerno)
libro: Atti del ABCD - Ph.D. meeting - ()

11573/1344887 - 2018 - Potential targeted therapy for T-cell acute lymphoblastic leukemia: perturbing ER/UPR signaling via Notch3 down-regulation
Giuli, Mv; Diluvio, G; Giuliani, E; Bellavia, D; Palermo, R; Screpanti, I; Checquolo, S - 04d Abstract in atti di convegno
congresso: 31st Annual conference of Italian Association of Cell Cultures (AICC) (Bologna, Italy)
libro: Cell communication and signaling: how to turn bad language into positive one - ()

11573/1258520 - 2018 - Natural products inspired modulators of cancer stem cells-specific signaling pathways notch and hedgehog
Palermo, Rocco; Ghirga, Francesca; Piccioni, Maria Grazia; Bernardi, Flavia; Zhdanovskaya, Nadezda; Infante, Paola; Mori, Mattia - 01g Articolo di rassegna (Review)
rivista: CURRENT PHARMACEUTICAL DESIGN (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 4251-4269 - issn: 1381-6128 - wos: WOS:000458726500004 (19) - scopus: 2-s2.0-85063684783 (27)

11573/1559745 - 2018 - Synthesis of Chalcone Derivatives As Inhibitors Of Notch Signaling In T-cell Acute Lymphoblastic Leukemia
Romeo, Isabella; Tottone, Luca; Palermo, Rocco; Mori, Mattia; Screpanti, Isabella; Botta, Bruno; Quaglio, Deborah; Ingallina, Cinzia - 04f Poster
congresso: COST ACTION CM1407: 3rd Training School: Computational modeling tools in drug discovery with natural products (Universidad La Laguna, Tenerife (Spain))
libro: Synthesis of Chalcone Derivatives as inhibitors of Notch signaling in T-cell acute lymphoblastic leukemia - ()

11573/1022327 - 2017 - Cytotoxic activity of Juglone against Notch3-overexpressing T-cell acute lymphoblastic leukemia: targeting the ER/UPR signaling
Giuli, Mv; Diluvio, G.; Giuliani, Eugenia; Bellavia, D.; Palermo, R.; Screpanti, I.; Checquolo, S. - 04d Abstract in atti di convegno
libro: Notch meeting X - ()

11573/1114777 - 2017 - Role of Notch3 in sustaining UPR signaling in Notch3-overexpressing T-cell acute lymphoblastic leukemia.
Giuli, Mv; Diluvio, G; Giuliani, E; Bellavia, D; Palermo, R; Screpanti, I; Checquolo, S - 04d Abstract in atti di convegno
congresso: SIPMeT "Young Scientist Meeting" (Milano)
libro: Atti del SIPMeT "Young Scientist Meeting" - ()

11573/966707 - 2017 - Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia
Mori, Mattia; Tottone, Luca; Quaglio, Deborah; Zhdanovskaya, Nadezda; Ingallina, Cinzia; Fusto, Marisa; Ghirga, Francesca; Peruzzi, Giovanna; Crestoni, Maria Elisa; Simeoni, Fabrizio; Giulimondi, Francesca; Talora, Claudio; Botta, Bruno; Screpanti, Isabella; Palermo, Rocco - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 2213- - issn: 2045-2322 - wos: WOS:000401614900071 (45) - scopus: 2-s2.0-85019925811 (43)

11573/932442 - 2017 - Manipulation of lipoplex concentration at the cell surface boosts transfection efficiency in hard-to-transfect cells
Palchetti, Sara; Pozzi, Daniela; Marchini, Cristina; Amici, Augusto; Andreani, Cristina; Bartolacci, Caterina; Digiacomo, Luca; Gambini, Valentina; Cardarelli, Francesco; Di Rienzo, Carmine; Peruzzi, Giovanna; Amenitsch, Heinz; Palermo, Rocco; Screpanti, Isabella; Caracciolo, Giulio - 01a Articolo in rivista
rivista: NANOMEDICINE (New York, NY : Elsevier, c2005-) pp. 681-691 - issn: 1549-9634 - wos: WOS:000396940200031 (24) - scopus: 2-s2.0-85010451201 (24)

11573/969457 - 2017 - Maml1 acts cooperatively with Gli proteins to regulate Sonic hedgheog signaling pathway
Quaranta, Roberta; Pelullo, Maria; Zema, Sabrina; Nardozza, Francesca; Checquolo, Saula; Lauer, Dieter Matthias; Bufalieri, Francesca; Palermo, Rocco; Felli, Maria Pia; Vacca, Alessandra; Talora, Claudio; Di Marcotullio, Lucia; Screpanti, Isabella; Bellavia, Diana - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000406870400031 (30) - scopus: 2-s2.0-85035040836 (28)

11573/1083868 - 2016 - Effect of Argania spinosa oil extract on proliferation and Notch1 and ERK1/2 signaling of T-cell acute lymphoblastic leukemia cell lines
Aribi, Boutheyna; Zerizer, Sakina; Kabouche, Zahia; Screpanti, Isabella; Palermo, Rocco - 01a Articolo in rivista
rivista: FOOD AND AGRICULTURAL IMMUNOLOGY (Carfax Publishing Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813000, EMAIL: madeline.sims@tandf.co.uk, INTERNET: http://www.carfax.co.uk, http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 350-357 - issn: 0954-0105 - wos: WOS:000372023700005 (4) - scopus: 2-s2.0-84959897260 (6)

11573/928933 - 2016 - The loss of ATP2C1 impairs the DNA damage response and induces altered skin homeostasis: Consequences for epidermal biology in Hailey-Hailey disease
Cialfi, Samantha; Le Pera, Loredana; De Blasio, Carlo; Mariano, Germano; Palermo, Rocco; Zonfrilli, Azzurra; Uccelletti, Daniela; Palleschi, Claudio; Biolcati, Gianfranco; Barbieri, Luca; Screpanti, Isabella; Talora, Claudio - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000392122500001 (14) - scopus: 2-s2.0-84982193844 (17)

11573/846078 - 2016 - Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression
Franciosa, Giulia; Diluvio, Giulia; Del Gaudio, Francesca; Giuli, Maria Valeria; Palermo, Rocco; Grazioli, Paola; Campese, Antonio Francesco; Talora, Claudio; Bellavia, Diana; D'amati, Giulia; Besharat, Zein Mersini; Nicoletti, Carmine; Siebel, Christian William; Choy, Lisa; Rustighi, Alessandra; Del Sal, Giannino; Screpanti, Isabella; Checquolo, Saula - 01a Articolo in rivista
rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 4741-4751 - issn: 0950-9232 - wos: WOS:000383324700007 (43) - scopus: 2-s2.0-84958093172 (44)

11573/899112 - 2016 - Regulation of proapoptotic proteins Bak1 and p53 by miR-125b in an experimental model of Alzheimer's disease: Protective role of 17β-estradiol
Micheli, Francesca; Palermo, Rocco; Talora, Claudio; Ferretti, Elisabetta; Vacca, Alessandra; Napolitano, Maddalena - 01a Articolo in rivista
rivista: NEUROSCIENCE LETTERS (Elsevier Science Ireland Limited:PO Box 85, Limerick Ireland:011 353 61 709600, 011 353 61 61944, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 353 61 709114) pp. 234-240 - issn: 0304-3940 - wos: WOS:000382409000041 (23) - scopus: 2-s2.0-84978886835 (25)

11573/782968 - 2015 - The deregulated expression of miR-125b in acute myeloid leukemia is dependent on the transcription factor C/EBPalpha
Vargas Romero, Paula Estefania; Cialfi, Samantha; Palermo, Rocco; De Blasio, Carlo; Checquolo, Saula; Bellavia, Diana; Chiaretti, Sabina; Foa, Roberto; Amadori, Alberto; Gulino, Alberto; Zardo, Giuseppe; Talora, Claudio; Screpanti, Isabella - 01f Lettera, Nota
rivista: LEUKEMIA (-, LONDON, ENGLAND: NATURE PUBLISHING GROUP, -London,United Kingdom: Macmillan Magazines Limited -[Baltimore, Md.] : Williams & Wilkins, [c1987]-) pp. 2442-2445 - issn: 0887-6924 - wos: WOS:000366393900032 (29) - scopus: 2-s2.0-84951569042 (28)

11573/670477 - 2014 - Loss of Notch1-dependent p21(Waf1/Cip1) expression influences the Notch1 outcome in tumorigenesis
Cialfi, Samantha; Palermo, Rocco; Manca, Sonia; De Blasio, Carlo; Vargas Romero, Paula Estefania; Checquolo, Saula; Bellavia, Diana; Uccelletti, Daniela; Saliola, Michele; Angelo, D’Alessandro; Lello, Zolla; Gulino, Alberto; Screpanti, Isabella; Talora, Claudio - 01a Articolo in rivista
rivista: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 2046-2055 - issn: 1538-4101 - wos: WOS:000338041700011 (23) - scopus: 2-s2.0-84903756189 (25)

11573/557496 - 2014 - Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38α modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A
Germani, Aldo; Antonio, Matrone; Grossi, Valentina; Alessia, Peserico; Paola, Sanese; Micaela, Liuzzi; Palermo, Rocco; Stefania, Murzilli; Campese, Antonio Francesco; Giuseppe, Ingravallo; Canettieri, Gianluca; Tugsan, Tezil; Cristiano, Simone - 01a Articolo in rivista
rivista: CANCER LETTERS (Elsevier Science Ireland Limited:PO Box 85, Limerick Ireland:011 353 61 709600, 011 353 61 61944, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 353 61 709114) pp. 110-118 - issn: 0304-3835 - wos: WOS:000331688700013 (40) - scopus: 2-s2.0-84893131728 (41)

11573/557636 - 2014 - Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia
Kumar, Vivek; Palermo, Rocco; Talora, Claudio; Campese, Antonio Francesco; Checquolo, Saula; Bellavia, Diana; Tottone, Luca; Testa, G.; Miele, Evelina; Indraccolo, S.; Amadori, A.; Ferretti, Elisabetta; Gulino, Alberto; Vacca, Alessandra; Screpanti, Isabella - 01a Articolo in rivista
rivista: LEUKEMIA (-, LONDON, ENGLAND: NATURE PUBLISHING GROUP, -London,United Kingdom: Macmillan Magazines Limited -[Baltimore, Md.] : Williams & Wilkins, [c1987]-) pp. 2324-2335 - issn: 0887-6924 - wos: WOS:000346177500009 (134) - scopus: 2-s2.0-84925282873 (143)

11573/649693 - 2014 - Numb-dependent integration of pre-TCR and p53 function in T-cell precursor development.
Martin Blanco, Nm; Checquolo, Saula; Del Gaudio, Francesca; Palermo, Rocco; Franciosa, Giulia; Di Marcotullio, Lucia; Gulino, Alberto; Canelles, M; Screpanti, Isabella - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. Article Number: e1472- - issn: 2041-4889 - wos: WOS:000344994000044 (5) - scopus: 2-s2.0-84925810051 (5)

11573/543225 - 2014 - The Molecular Basis of Notch Signaling Regulation: A Complex Simplicity
Palermo, Rocco; Checquolo, Saula; Bellavia, Diana; Talora, Claudio; Screpanti, Isabella - 01a Articolo in rivista
rivista: CURRENT MOLECULAR MEDICINE (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 34-44 - issn: 1566-5240 - wos: WOS:000329187800004 (32) - scopus: 2-s2.0-84891837770 (33)

11573/656612 - 2014 - Notch3/Jagged1 Circuitry Reinforces Notch Signaling and Sustains T-ALL.
Pelullo, Maria; Quaranta, Roberta; Talora, Claudio; Checquolo, Saula; Cialfi, Samantha; Felli, Maria Pia; Te Kronnie, G; Borga, C; Besharat, Zein Mersini; Palermo, Rocco; Di Marcotullio, Lucia; Capobianco, Aj; Gulino, Alberto; Screpanti, Isabella; Bellavia, Diana - 01a Articolo in rivista
rivista: NEOPLASIA (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 1007-1017 - issn: 1522-8002 - wos: WOS:000347172100002 (43) - scopus: 2-s2.0-85003322506 (43)

11573/577411 - 2014 - The epigenetic factor BORIS/CTCFL regulates the NOTCH3 gene expression in cancer cells.
Zampieri, Michele; Ciccarone, Fabio; Palermo, Rocco; Cialfi, Samantha; Claudio, Passananti; Chiaretti, Sabina; Nocchia, Daniela; Talora, Claudio; Screpanti, Isabella; Caiafa, Paola - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS (Amsterdam-UK : Elsevier) pp. 813-825 - issn: 1874-9399 - wos: WOS:000341347900008 (23) - scopus: 2-s2.0-84904126646 (26)

11573/759618 - 2013 - The prolyl-isomerase Pin1 regulates Notch3 receptor maturation process by influencing membrane migration of its transmembrane form
Checquolo, Saula; Franciosa, Giulia; Del Gaudio, Francesca; Diluvio, Giulia; Palermo, R.; Gulino, Alberto; Screpanti, Isabella - 04d Abstract in atti di convegno
congresso: ESF-EMBO RESEARCH CONFERENCE (POLONIA)
libro: ESF-EMBO RESEARCH CONFERENCE - ()

11573/759623 - 2013 - The prolyl-isomerase Pin1 regulates Notch3 receptor maturation by influencing its migration to the cell membrane
Checquolo, Saula; Franciosa, Giulia; Del Gaudio, Francesca; Diluvio, Giulia; Palermo, Rocco; Talora, Claudio; Bellavia, Diana; Gulino, Alberto; Screpanti, Isabella - 04d Abstract in atti di convegno
congresso: SIPMET 2013 (Roma)
libro: SIPMET 2013 - ()

11573/759629 - 2013 - The prolyl-isomerase Pin1 regulates Notch3 receptor maturation process by influencing membrane migration of its transmembrane form
Checquolo, Saula; Franciosa, Giulia; Del Gaudio, Francesca; Diluvio, Giulia; Palermo, Rocco; Talora, Claudio; Bellavia, Diana; Gulino, Alberto; Screpanti, Isabella - 04d Abstract in atti di convegno
congresso: ABCD 2013 (Ravenna)
libro: ABCD 2013 - ()

11573/484435 - 2013 - Glucocorticoid sensitivity of T-cell lymphoblastic leukemia/lymphoma is associated with glucocorticoid receptor-mediated inhibition of Notch1 expression
Cialfi, Samantha; Palermo, Rocco; Sonia, Manca; Checquolo, Saula; Bellavia, Diana; Pelullo, Maria; Quaranta, Roberta; Dominici, Carlo; Gulino, Alberto; Screpanti, Isabella; Talora, Claudio - 01a Articolo in rivista
rivista: LEUKEMIA (-, LONDON, ENGLAND: NATURE PUBLISHING GROUP, -London,United Kingdom: Macmillan Magazines Limited -[Baltimore, Md.] : Williams & Wilkins, [c1987]-) pp. 485-488 - issn: 0887-6924 - wos: WOS:000315553600027 (30) - scopus: 2-s2.0-84873566711 (30)

11573/434259 - 2012 - Acetylation controls Notch3 stability and function in T-cell leukemia
Palermo, Rocco; Checquolo, Saula; A., Giovenco; Grazioli, Paola; Kumar, Vivek; Campese, Antonio Francesco; Giorgi, Alessandra; Napolitano, Maddalena; Canettieri, Gianluca; G., Ferrara; Schinina', Maria Eugenia; Maroder, Marella; Frati, Luigi; Gulino, Alberto; Vacca, Alessandra; Screpanti, Isabella - 01a Articolo in rivista
rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 3807-3817 - issn: 0950-9232 - wos: WOS:000307924900007 (46) - scopus: 2-s2.0-84865202947 (47)

11573/759615 - 2011 - The Prolyl-Isomerase PIN1 represent a regulator of Notch3 activity
Checquolo, Saula; Palermo, Rocco; Franciosa, Giulia; Pelullo, Maria; Bellavia, Diana; Gulino, Alberto; Screpanti, Isabella - 04d Abstract in atti di convegno
congresso: THE NOTCH MEETING V (ATENE)
libro: THE NOTCH MEETING V - ()

11573/378032 - 2011 - Protective effect of pioglitazone, a PPARγ ligand, in a 3 nitropropionic acid model of Huntington's disease
Napolitano, Maddalena; Costa, Loredana; Palermo, Rocco; Alessandro, Giovenco; Vacca, Alessandra; Gulino, Alberto - 01a Articolo in rivista
rivista: BRAIN RESEARCH BULLETIN (Phoenix N.Y.: ANKHO International Inc., c1976-) pp. 231-237 - issn: 0361-9230 - wos: WOS:000292431200022 (42) - scopus: 2-s2.0-79957858160 (41)

11573/145820 - 2010 - Differential subcellular localization regulates c-Cbl E3 ligase activity upon Notch3 protein in T-cell leukemia
Checquolo, Saula; Palermo, Rocco; Cialfi, Samantha; Ferrara, Grazia; C., Oliviero; Talora, Claudio; Bellavia, Diana; A., Giovenco; Grazioli, Paola; Frati, Luigi; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista
rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 1463-1474 - issn: 0950-9232 - wos: WOS:000275392400005 (27) - scopus: 2-s2.0-77949425560 (27)

11573/228870 - 2008 - NF-kB/NOS cross-talk induced by mitochondrial complex II inhibition: Implications for Huntington's disease
Napolitano, Maddalena; Daniela, Zei; Diego, Centonze; Palermo, Rocco; Giorgio, Bernardi; Vacca, Alessandra; Paolo, Calabresi; Gulino, Alberto - 01a Articolo in rivista
rivista: NEUROSCIENCE LETTERS (Elsevier Science Ireland Limited:PO Box 85, Limerick Ireland:011 353 61 709600, 011 353 61 61944, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 353 61 709114) pp. 241-246 - issn: 0304-3940 - wos: WOS:000255302400001 (36) - scopus: 2-s2.0-40849123838 (37)

11573/60056 - 2006 - Oxytocin induces HMGB1 expression and Nf-Kb activation in human fetal membranes at term gestation
Palermo, R.; Maiani, G.; Realacci, A. V. A. C. C. A. M.; Di Vito, M.; Ticconi, C.; Zicari, Alessandra; Mari, Emanuela - 04a Atto di comunicazione a congresso
rivista: PLACENTA (Harcourt Publishers Limited:Foots Cray High Street, Sidcup Kent DA14 5HP United Kingdom:011 44 20 83085700, EMAIL: journals@harcourt.com, INTERNET: http://www.harcourt-international.com, Fax: 011 44 20 83085876) pp. A47- - issn: 0143-4004 - wos: (0) - scopus: (0)
congresso: IFPA2006 (Kobe- Japan)
libro: Placenta - ()

11573/358672 - 2006 - Cross talk among Notch3, pre-TCR, and Tal1 in T-cell development and leukemogenesis.
Talora, Claudio; Cialfi, Samantha; Oliviero, Christian; Palermo, Rocco; Pascucci, M; Frati, Luigi; Vacca, Alessandra; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista
rivista: BLOOD (New York: Elsevier Inc. [Washington DC etc.]: American Society of Hematology) pp. 3313-3320 - issn: 0006-4971 - wos: WOS:000236833500051 (33) - scopus: 2-s2.0-33645751939 (37)

11573/362204 - 2006 - Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.
Vacca, Alessandra; Felli, Maria Pia; Palermo, Rocco; Di Mario, G; Calce, A; Di Giovine, Monica; Frati, Luigi; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista
rivista: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 1000-1008 - issn: 0261-4189 - wos: WOS:000236225400008 (116) - scopus: 2-s2.0-33644864057 (116)

11573/358248 - 2005 - PKC theta mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia
Felli, Maria Pia; Vacca, Alessandra; Calce, A; Bellavia, Diana; Campese, Antonio Francesco; Grillo, R; Di Giovine, M; Checquolo, Saula; Talora, Claudio; Palermo, Rocco; Di Mario, G; Frati, Luigi; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista
rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 992-1000 - issn: 0950-9232 - wos: WOS:000226749200005 (61) - scopus: 2-s2.0-13944266008 (65)

11573/240487 - 2005 - The archaeal eIF2 homologue: Functional properties of an ancient translation initiation factor
Pedulla, N.; Palermo, R.; Hasenoehrl, D.; Blasi, U.; Cammarano, Piero; Londei, Paola - 01a Articolo in rivista
rivista: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. 1804-1812 - issn: 0305-1048 - wos: WOS:000228398400020 (59) - scopus: 2-s2.0-15944425052 (65)

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