ROCCO AMENDOLARA

PhD Student

PhD program:: XXXVII
email: rocco.amendolara@uniroma1.it
phone: 0649970952
building: 5 (ex Clinica Medica II), Policlinico Umberto I
room: 21




supervisor: Prof.ssa Raffaella Buzzetti
advisor: Prof.ssa Raffaella Buzzetti
co-supervisor: Dott. Ernesto Maddaloni

Research: Immuno-metabolic and phenotypic characterization of autoimmune diabetes and its complications.

WORK ADDRESS
Dept. of Experimental Medicine
Viale del Policlinico 155, 00161 Rome (RM)

SUPERVISOR
Raffaella Buzzetti
Full Professor, Endocrinology, MED/13
CO-SUPERVISOR
Dr. Ernesto Maddaloni

PREVIOUS RESEARCH EXPERIENCE
03/2022 - present: internship at the laboratory of Hormonal Diagnostics, Seminology and Seed Bank (SMID04), Sapienza University of Rome.
May-October 2021: collaboration with the Italian Society of Diabetology within the national project Non Insulin Requiring Autoimmune Diabetes (NIRAD).

LINES OF RESEARCH
- Study of genetic, molecular, and pathophysiological heterogeneity of autoimmune diabetes;
- Evaluation of clinical and pathophysiological features of emerging complications of diabetes mellitus;
- Study of molecular mechanisms of the correlation between bone metabolism and vascular complications of diabetes mellitus;
- Immuno-metabolic and phenotypic characterization of obesity in autoimmune diabetes and its consequences.

CAREER
2023-ongoing: Post-graduate Student in Clinical Pathology and Clinical Biochemistry, Dept. of Experimental Medicine, “Sapienza” University of Rome, Italy
2021-ongoing: PhD in Molecular Medicine, Dept. of Molecular Medicine, Sapienza University of Rome
2018 - 2021: Master degree in Medical Biotechnology with honors, Sapienza University of Rome.
2015 - 2018: Bachelor's degree in Biology with honors, Sapienza University of Rome.

SKILLS
- Assay of analytes: ELISA and RIA
- In vitro transcription and translation techniques
- Radioisotopic labeling of analytes
- Cell cultures of human monocytes
- Isolation of peripheral blood mononuclear cells (PBMC) from human
- Flow cytometry
- Optical microscopy
- DNA extraction from human blood samples


Research products

11573/1714875 - 2024 - No differences in kidney function decline between people with type 2 diabetes starting a sodium-glucose cotransporter 2 inhibitor or a glucagon-like peptide-1 receptor agonist: a real-world retrospective comparative observational study
Bodini, Sara; Pieralice, Silvia; D'onofrio, Luca; Mignogna, Carmen; Coraggio, Lucia; Amendolara, Rocco; Risi, Renata; Salducci, Mauro; Buzzetti, Raffaella; Maddaloni, Ernesto - 01a Articolo in rivista
paper: CLINICAL THERAPEUTICS (Excerpta Medica / US:PO Box 3085:Princeton, NJ 08543:(908)874-8550, Fax: (908)874-5611) pp. 1-7 - issn: 0149-2918 - wos: (0) - scopus: 2-s2.0-85197444157 (0)

11573/1705556 - 2024 - Immune checkpoint modulators in early clinical development for the treatment of type 1 diabetes
Maddaloni, Ernesto; Amendolara, Rocco; Balena, Angela; Latino, Alessandro; Sessa, Rosario Luigi; Buzzetti, Raffaella - 01g Articolo di rassegna (Review)
paper: EXPERT OPINION ON INVESTIGATIONAL DRUGS (-London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 1-16 - issn: 1354-3784 - wos: (0) - scopus: (0)

11573/1701066 - 2024 - Saxagliptin/dapagliflozin is non‐inferior to insulin glargine in terms of β‐cell function in subjects with latent autoimmune diabetes in adults: A 12‐month, randomized, comparator‐controlled pilot study
Maddaloni, Ernesto; Naciu, Anda M.; Mignogna, Carmen; Galiero, Raffaele; Amendolara, Rocco; Fogolari, Marta; Satta, Chiara; Serafini, Chiara; Angeletti, Silvia; Cavallo, Maria Gisella; Cossu, Efisio; Sasso, Ferdinando Carlo; Buzzetti, Raffaella; Pozzilli, Paolo; Barchetta, Ilaria - 01a Articolo in rivista
paper: DIABETES, OBESITY AND METABOLISM (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. - - issn: 1462-8902 - wos: (0) - scopus: (0)

11573/1691316 - 2023 - Lack of Association between Serum Chitotriosidase Activity and Arterial Stiffness in Type 2 Diabetes without Cardiovascular Complications
D’Onofrio, Luca; Amendolara, Rocco; Mignogna, Carmen; Leto, Gaetano; Tartaglione, Lida; Mazzaferro, Sandro; Maddaloni, Ernesto; Buzzetti, Raffaella - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-9 - issn: 1422-0067 - wos: WOS:001103257400001 (0) - scopus: 2-s2.0-85176462993 (1)

11573/1663163 - 2023 - Reduced early response to SARS-CoV2 vaccination in people with type 1 and type 2 diabetes, a six months follow-up study. The CoVaDiab study I
D'onofrio, Luca; Fogolari, Marta; Amendolara, Rocco; Siena, Antonio; De Fata, Riccardo; Davini, Flavio; Coraggio, Lucia; Mignogna, Carmen; Moretti, Chiara; Maddaloni, Ernesto; Angeletti, Silvia; Buzzetti, Raffaella - 01a Articolo in rivista
paper: DIABETES/METABOLISM RESEARCH AND REVIEWS (Chichester UK: John Wiley & Sons, ©2000-) pp. 1-7 - issn: 1520-7560 - wos: WOS:000904036300001 (3) - scopus: 2-s2.0-85145309567 (4)

11573/1675564 - 2023 - Association of osteocalcin, osteoprotegerin, and osteopontin with cardiovascular disease and retinopathy in type 2 diabetes
Maddaloni, Ernesto; Coraggio, Lucia; Amendolara, Rocco; Baroni, Marco G; Cavallo, Maria G; Copetti, Massimiliano; Cossu, Efisio; D'angelo, Paola; D'onofrio, Luca; Cosmo, Salvatore De; Leonetti, Frida; Morano, Susanna; Morviducci, Lelio; Napoli, Nicola; Prudente, Sabrina; Pugliese, Giuseppe; Park, Kyoungmin; Holman, Rury R; Trischitta, Vincenzo; Buzzetti, Raffaella - 01a Articolo in rivista
paper: DIABETES/METABOLISM RESEARCH AND REVIEWS (John Wiley & Sons Limited:1 Oldlands Way, Bognor Regis, P022 9SA United Kingdom:011 44 1243 779777, EMAIL: cs-journals@wiley.co.uk, INTERNET: http://www.wiley.co.uk, Fax: 011 44 1243 843232) pp. 1-9 - issn: 1520-7552 - wos: WOS:000956423900001 (3) - scopus: 2-s2.0-85151070822 (3)

11573/1573616 - 2021 - Impact of cardiovascular disease on clinical outcomes in hospitalized patients with Covid-19. a systematic review and meta-analysis
Maddaloni, E.; D'onofrio, L.; Siena, A.; Luordi, C.; Mignogna, C.; Amendolara, R.; Cavallari, I.; Grigioni, F.; Buzzetti, R. - 01g Articolo di rassegna (Review)
paper: INTERNAL AND EMERGENCY MEDICINE (Milano : Springer Verlag Italia Roma : CEPI) pp. 1-11 - issn: 1828-0447 - wos: WOS:000673721700001 (6) - scopus: 2-s2.0-85110813556 (6)

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