RAFFAELE STRIPPOLI

Associate professor


email: raffaele.strippoli@uniroma1.it
phone: +393281485838
building: V Clinica Medica (Policlinico Umberto I)


I am interested in molecular mechanisms controlling the induction/reversal of Epithelial to Mesenchymal Transition (EMT) and fibrosis. In particular, I focused my investigation in intracellular mechanisms controlling the plasticity of mesothelial cells in inflammatory/fibrogenic conditions. I and collaborators elucidated the role of NF-kB/ERK1/2/Snail axis in EMT induction/reversal and I analyzed p38-NF-kB and ERK1/2-SMADs cross talks. In a recent study, I elucidated the role of Caveolin1 in limiting EMT induction due to repression of MEK/ERK pathway in in vitro and in-vivo models.
I am presently involved in research projects related to mechanical regulation of EMT and to the control of EMT induction/reversal by epigenetic factors in mesothelial cells and in other projects aimed to characterize novel proteins relevant for EMT dynamics.
Moreover, I have been implicated in the study of pathogenetic mechanisms of rheumatic inflammatory diseases, such as juvenile idiopathic arthritis (JIA) and macrophage activation syndrome (MAS/HLH). Taking advantage of both murine (IL-6 transgenic mice) and cellular (mononuclear cells from synovial fluid and synovial fibroblasts) models, we analysed interrelations between cytokines, especially IL-6, and Toll-like receptor (TLR) ligands in the genesis of the inflammatory response, leading eventually to fibrotic damage. We found that a cooperation between TLR- and cytokine-induced signals enhances the activity of both mononuclear and stromal cells, leading to an exacerbation of the inflammatory response. These discoveries contributed to constitute the rational for the ongoing introduction of new biologic drugs, such as anti-IL-6 and anti-IFN mAbs, for treatment of JIA and other rheumatic diseases.


Part II – Education
University graduation: Medicine, Sapienza University full marks and honors
Specialty: Laboratory Medicine, Sapienza University
PhD: Immunology, Sapienza University

Part III – Appointments

IIIA – Academic Appointments
01/09/2013-30/08/2018 Sapienza University Dipartimento di Biotecnologie cellulari ed Ematologia Assistant Professor (RTDA)
01/09/2018-Now Sapienza University Dipartimento di Medicina Molecolare Assistant Professor Tenure Track (RTDB)

IIIB – Other Appointments
01-02-2002 30-05-2002 Fulbright Commission Fulbright Fellowship (spent at Butcher lab Stanford University, Palo Alto)
01-07-2005 30-06-2006 FIRC foundation FIRC Fellowship (spent at CNIC, Madrid, Del Pozo lab)
01-01-2007 30-01-2009 Ministerio Economia y Competitividad, Fundaciòn CNIC Carlos III, Madrid Spain Three years Rìo Hortega Fellowship (for MD Residents), (spent at CNIC, Madrid, Del Pozo lab)
01-09-2008 30-08-2012 IRCCS Bambino Gesù Rome Italy Research Fellowship, Lab De Benedetti

Part IV - Society memberships
2000 SIICA Società Italiana di Immunologia Immunologia Clinica ed Allergologia
2007 TEMTIA the EMT International Association
2008 Pres, Pediatric Rheumatology European Society
2015 ABCD, Associazione di Biologia Cellulare e del Differenziamento

Awards and Honors
2009 Disease Models and Mechanisms (DMM) research presentation Grant
2014 Invited Speaker at the International Symposium on Translational Approaches to Autoinflammatory Diseases 15th + 16th May 2014, Münster Germany
2019 Invited Speaker, Centro Nacional de Biologia Molecular (CBM) Severo Ochoa (Madrid, Spain) cycle of conferences 2018/2019

Evaluation of Research projects and editorial activity
2011 Independent evaluator of Greek National Action 'Cooperation 2011' (Evaluation of a competitive research project in cancer cell apoptosis from European Union/ Ministry of Education, Life Long Learning and Religious Affairs cofounding)
2016 Independent evaluator of peer review of Application for Kidney Research UK
2016 Lead Guest Editor, Mediators of Inflammation
2017 Lead Guest Editor, Frontiers in Pharmacology
2018 Guest Editor, Oxidative Medicine and Cellular Longevity
2019 Guest Editor, Journal of Oncology

Peer Review activity
2010-2019 Peer Review activity traced in Publons since 2013 (https://publons.com/author/1192573/raffaele-strippoli#profile) for Journal of Biological Chemistry, Cell Death and Differentiation, Journal of Cell Science, PloS One, Translational Research, Journal of Rheumatology, Pharmaceutical Biology, Laboratory Investigation, Cellular Physiology and Biochemistry; American Journal of Nephrology, Pharmacological Reports, World Journal Gastroenterology, Scientific Reports, the Journal of Pathology, Oncotarget, Biochimica and Biophysica acta (BBA), FEBS journal, Frontiers of Medicine, Frontiers in Pharmacology, Frontiers of Medicine, BMC Nephrology. Journal of Cell Science,

Part V
International Collaborations
Miguel Angel del Pozo Mechanoadaptation & Caveolae Biology Lab, Cell and Developmental Biology Area, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid 28029, Spain.
Manuel Lopez Cabrera Molecular Biology Research Centre Severo Ochoa, Spanish National Research Council Madrid, Spain
Marco Cordani Institute for Advanced Studies in Nanoscience (IMDEA Nanociencia)Ciudad Universitaria de Cantoblanco Madrid Spain
Teijo Pellinen Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland.
Dirk Holzinger Department of Pediatric Rheumatology and Immunology, University Children's Hospital Münster, Domagkstr. 3, 48149 Münster, Germany.

Part VI Summary of Scientific Achievements

Patents 2
Patent 1 Use of tak1 inhibitors in the prevention and treatment of peritoneal membrane failure P201031439 ES1997.8 September 28th 2010 https://www.google.com/patents/WO2012042091A3?cl=en 2010
Patent 1 Mek 1/2 inhibitors for the treatment of peritoneal fibrosis PCT/ES2009/070348 https://encrypted.google.com/patents/WO2010020703A1?cl=zh 2009

Papers
Total number of products (papers) 36 Scopus 2000-2019
Total Citations 1020 (Scopus)
Average Citations per Product 28.5 (Scopus)
Hirsch (H) index 18 (Scopus)


Research products

11573/1703577 - 2024 - Immune checkpoints between epithelial-mesenchymal transition and autophagy: A conflicting triangle
Cordani, Marco; Strippoli, Raffaele; Trionfetti, Flavia; Barzegar Behrooz, Amir; Rumio, Cristiano; Velasco, Guillermo; Ghavami, Saeid; Marcucci, Fabrizio - 01g Articolo di rassegna (Review)
paper: CANCER LETTERS (Elsevier Science Ireland Limited:PO Box 85, Limerick Ireland:011 353 61 709600, 011 353 61 61944, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 353 61 709114) pp. 1-18 - issn: 0304-3835 - wos: (0) - scopus: 2-s2.0-85185565708 (0)

11573/1703579 - 2024 - Contribution of Autophagy to Epithelial Mesenchymal Transition Induction during Cancer Progression
Strippoli, Raffaele; Niayesh-Mehr, Reyhaneh; Adelipour, Maryam; Khosravi, Arezoo; Cordani, Marco; Zarrabi, Ali; Allameh, Abdolamir - 01g Articolo di rassegna (Review)
paper: CANCERS (Basel: MDPI) pp. 1-31 - issn: 2072-6694 - wos: WOS:001168344700001 (0) - scopus: 2-s2.0-85185907914 (0)

11573/1700487 - 2024 - HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling
Terri, Michela; Sandoval, Pilar; Bontempi, Giulio; Montaldo, Claudia; Tomero-Sanz, Henar; De Turris, Valeria; Trionfetti, Flavia; Pascual-Antón, Lucía; Clares-Pedrero, Irene; Battistelli, Cecilia; Valente, Sergio; Zwergel, Clemens; Mai, Antonello; Rosanò, Laura; Del Pozo, Miguel Ángel; Sánchez-Álvarez, Miguel; Cabañas, Carlos; Tripodi, Marco; López-Cabrera, Manuel; Strippoli, Raffaele - 01a Articolo in rivista
paper: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. - - issn: 1756-9966 - wos: (0) - scopus: (0)

11573/1702828 - 2024 - Mechanisms of mesothelial cell response to viral infections: HDAC1-3 inhibition blocks poly(I:C)-induced type I interferon response and modulates the mesenchymal/inflammatory phenotype
Trionfetti, Flavia; Montaldo, Claudia; Caiello, Ivan; Bontempi, Giulio; Terri, Michela; Tiberi, Marta; Marchant, Vanessa; Domenici, Alessandro; Menè, Paolo; Cordani, Marco; Zwergel, Clemens; Prencipe, Giusi; Ruiz-Ortega, Marta; Valente, Sergio; Mai, Antonello; Tripodi, Marco; Strippoli, Raffaele - 01a Articolo in rivista
paper: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (Lausanne : Frontiers Media SA, 2011-) pp. - - issn: 2235-2988 - wos: (0) - scopus: (0)

11573/1690636 - 2023 - Editorial: Autophagy modulation in cancer treatment utilizing nanomaterials and nanocarriers
Cordani, Marco; Condello, Maria; Meschini, Stefania; Strippoli, Raffaele - 01m Editorial/Introduzione in rivista
paper: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. - - issn: 2234-943X - wos: WOS:001015254200001 (0) - scopus: 2-s2.0-85162217068 (0)

11573/1662777 - 2023 - Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells
Di Bello, Elisabetta; Sian, Veronica; Bontempi, Giulio; Zwergel, Clemens; Fioravanti, Rossella; Noce, Beatrice; Castiello, Carola; Tomassi, Stefano; Corinti, Davide; Passeri, Daniela; Pellicciari, Roberto; Mercurio, Ciro; Varasi, Mario; Altucci, Lucia; Tripodi, Marco; Strippoli, Raffaele; Nebbioso, Angela; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 115022- - issn: 0223-5234 - wos: WOS:000911596400001 (5) - scopus: 2-s2.0-85144323384 (5)

11573/1675051 - 2023 - Nanomedicine for autophagy modulation in cancer therapy: a clinical perspective
López-Méndez, Tania B; Sánchez-Álvarez, Miguel; Trionfetti, Flavia; Pedraz, José L.; Tripodi, Marco; Cordani, Marco; Strippoli, Raffaele; González-Valdivieso, Juan - 01g Articolo di rassegna (Review)
paper: CELL & BIOSCIENCE (London : BioMed Central) pp. - - issn: 2045-3701 - wos: WOS:000943663700001 (9) - scopus: 2-s2.0-85149920839 (13)

11573/1695097 - 2023 - BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress
Marchant, Vanessa; Trionfetti, Flavia; Tejedor-Santamaria, Lucia; Rayego-Mateos, Sandra; Rotili, Dante; Bontempi, Giulio; Domenici, Alessandro; Menè, Paolo; Mai, Antonello; Martín-Cleary, Catalina; Ortiz, Alberto; Ramos, Adrian M.; Strippoli, Raffaele; Ruiz-Ortega, Marta - 01a Articolo in rivista
paper: ANTIOXIDANTS (Basel: MDPI) pp. 1-19 - issn: 2076-3921 - wos: WOS:001137851500001 (0) - scopus: 2-s2.0-85180466019 (0)

11573/1695915 - 2023 - Metal-based nanoparticles in cancer therapy: Exploring photodynamic therapy and its interplay with regulated cell death pathways
Pashootan, Parya; Saadati, Fatemeh; Fahimi, Hossein; Rahmati, Marveh; Strippoli, Raffaele; Zarrabi, Ali; Cordani, Marco; Amin Moosavi, Mohammad - 01g Articolo di rassegna (Review)
paper: INTERNATIONAL JOURNAL OF PHARMACEUTICS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0378-5173 - wos: WOS:001128565300001 (0) - scopus: 2-s2.0-85178494268 (1)

11573/1690637 - 2023 - Geoffrey Cooper LA CELLULA
Strippoli, Raffaele; Amicone, Laura - 03e Traduzione di libro

11573/1696065 - 2023 - HDAC1-3 inhibition increases SARS-CoV-2 replication and productive infection in lung mesothelial and epithelial cells
Trionfetti, Flavia; Alonzi, Tonino; Bontempi, Giulio; Terri, Michela; Battistelli, Cecilia; Montaldo, Claudia; Repele, Federica; Rotili, Dante; Valente, Sergio; Zwergel, Clemens; Matusali, Giulia; Maggi, Fabrizio; Goletti, Delia; Tripodi, Marco; Mai, Antonello; Strippoli, Raffaele - 01a Articolo in rivista
paper: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (Lausanne : Frontiers Media SA, 2011-) pp. - - issn: 2235-2988 - wos: WOS:001130489700001 (1) - scopus: (0)

11573/1675041 - 2023 - Novel Aspects of the Immune Response Involved in the Peritoneal Damage in Chronic Kidney Disease Patients under Dialysis
Trionfetti, Flavia; Marchant, Vanessa; González-Mateo, Guadalupe T.; Kawka, Edyta; Márquez-Expósito, Laura; Ortiz, Alberto; López-Cabrera, Manuel; Ruiz-Ortega, Marta; Strippoli, Raffaele - 01g Articolo di rassegna (Review)
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 5763- - issn: 1422-0067 - wos: WOS:000955473500001 (5) - scopus: 2-s2.0-85151113415 (7)

11573/1691462 - 2023 - POLY(I:C) INDUCES MORPHOLOGICAL CHANGES AND TYPE I INTERFERON-MEDIATED INFLAMMATORY RESPONSE IN MESOTHELIAL CELLS FROM PERITONEUM
Trionfetti, Flavia; Marchant, Vanessa; Terri, Michela; Bontempi, Giulio; Domenici, Alessandro; Mene, Paolo; Ruiz-Ortega, Marta; Strippoli, Raffaele - 01h Abstract in rivista
paper: NEPHROLOGY DIALYSIS TRANSPLANTATION (Oxford: Oxford University Press.) pp. 1164-1164 - issn: 1460-2385 - wos: WOS:001022961100156 (0) - scopus: (0)

11573/1659806 - 2022 - Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells
Bontempi, Giulio; Terri, Michela; Garbo, Sabrina; Montaldo, Claudia; Mariotti, Davide; Bordoni, Veronica; Valente, Sergio; Zwergel, Clemens; Mai, Antonello; Marchetti, Alessandra; Domenici, Alessandro; Menè, Paolo; Battistelli, Cecilia; Tripodi, Marco; Strippoli, Raffaele - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. 965- - issn: 2041-4889 - wos: WOS:000885083500004 (6) - scopus: 2-s2.0-85142134241 (9)

11573/1663108 - 2022 - Clinical Trials Involving Chemotherapy- Based Nanocarriers in Cancer Therapy: State of the Art and Future Directions
Lopez-Mendez, Tania B.; Strippoli, Raffaele; Trionfetti, Flavia; Calvo, Pilar; Cordani, Marco; Juan Gonzalez-Valdivieso, And - 02a Capitolo o Articolo
book: Cancer Nanotechnology - ()

11573/1605129 - 2022 - SYNCRIP Modulates the Epithelial-Mesenchymal Transition in Hepatocytes and HCC Cells
Riccioni, V.; Trionfetti, F.; Montaldo, C.; Garbo, S.; Marocco, F.; Battistelli, C.; Marchetti, A.; Strippoli, R.; Amicone, L.; Cicchini, C.; Tripodi, M. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 913- - issn: 1661-6596 - wos: WOS:000748109700001 (5) - scopus: 2-s2.0-85122801338 (5)

11573/1627263 - 2022 - SYNCRIP modulates the epithelial-mesenchymal transition in hepatocytes and HCC Cells
Riccioni, V.; Trionfetti, F.; Montaldo, C.; Garbo, S.; Marocco, F.; Battistelli, C.; Marchetti, A.; Strippoli, R.; Amicone, L.; Cicchini, C.; Tripodi, M. - 04f Poster
conference: ABCD National Ph.D. Meeting (Salerno; Italy)
book: National Ph.D. Meeting Abstracts book - ()

11573/1612876 - 2022 - Exposure to b‐LED light while exerting antimicrobial activity on Gram‐negative and ‐positive bacteria promotes transient EMT‐like changes and growth arrest in keratinocytes
Terri, M.; Mancianti, N.; Trionfetti, F.; Casciaro, B.; De Turris, V.; Raponi, G.; Bontempi, G.; Montaldo, C.; Domenici, A.; Mene', P.; Mangoni, M. L.; Strippoli, R. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000755651500001 (1) - scopus: 2-s2.0-85124280849 (2)

11573/1565876 - 2021 - Editorial: new approaches to tackle EMT and fibrosis: from epigenetics to nanotechnology
Battistelli, Cecilia; Cordani, Marco; Diederich, Marc; Somoza, Álvaro; Valente, Sergio; Strippoli, Raffaele - 01m Editorial/Introduzione in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000686867300001 (0) - scopus: 2-s2.0-85113221898 (0)

11573/1471921 - 2021 - Design and functional validation of a mutant variant of the lncRNA HOTAIR to counteract Snail function in Epithelial-to-Mesenchymal Transition
Battistelli, Cecilia; Garbo, Sabrina; Riccioni, Veronica; Montaldo, Claudia; Santangelo, Laura; Vandelli, Andrea; Strippoli, Raffaele; Tartaglia, Gian Gaetano; Tripodi, Marco; Cicchini, Carla - 01a Articolo in rivista
paper: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 103-113 - issn: 0008-5472 - wos: WOS:000606529700011 (33) - scopus: 2-s2.0-85100339265 (37)

11573/1598845 - 2021 - Ovarian cancer-driven mesothelial-to-mesenchymal transition is triggered by the endothelin-1/β-arr1 axis
Del Rio Danila, ; Masi, Ilenia; Caprara, Valentina; Spadaro, Francesca; Ottavi, Flavia; Strippoli, Raffaele; Sandoval, Pilar; López-Cabrera, Manuel; Sainz De La Cuesta Ricardo, ; Bagnato, Anna; Rosanò, Laura - 01a Articolo in rivista
paper: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. 1-16 - issn: 2296-634X - wos: WOS:000730505200001 (6) - scopus: 2-s2.0-85121373785 (6)

11573/1565903 - 2021 - Definition and validation of serum biomarkers for optimal differentiation of hyperferritinaemic cytokine storm conditions in children: a retrospective cohort study
Kessel, C; . Fall N, .; Grom, A; De Jager, W.; Vastert, S.; Strippoli, Raffaele; Bracaglia, Claudia.; Sundberg, E.; Horne, A.; Ehl, S.; Ammann, S.; Wouters, C.; Lehmberg, K.; De Benedetti, F.; Park, Carolin; Hinze, C.; Wittkowski, H.; Kessel, K.; Beutel, K.; Foell, D.; Holzinger, D. - 01a Articolo in rivista
paper: THE LANCET. RHEUMATOLOGY (Oxford: Elsevier Ltd.) pp. - - issn: 2665-9913 - wos: WOS:000680053500014 (12) - scopus: 2-s2.0-85111198936 (12)

11573/1586405 - 2021 - Autophagy and the lysosomal system in cancer
Kumar, Suresh; Sánchez-Álvarez, Miguel; Lolo, Fidel-Nicolás; Trionfetti, Flavia; Strippoli, Raffaele; Marco, Cordani - 01g Articolo di rassegna (Review)
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000715401800001 (21) - scopus: 2-s2.0-85116992319 (24)

11573/1610922 - 2021 - Pleural mesothelial cells modulate the inflammatory/profibrotic response during SARS-CoV-2 infection
Matusali, Giulia; Trionfetti, Flavia; Bordoni, Veronica; Nardacci, Roberta; Falasca, Laura; Colombo, Daniele; Terri, Michela; Montaldo, Claudia; Castilletti, Concetta; Mariotti, Davide; Del Nonno, Franca; Capobianchi, Maria Rosaria; Agrati, Chiara; Tripodi, Marco; Strippoli, Raffaele - 01a Articolo in rivista
paper: FRONTIERS IN MOLECULAR BIOSCIENCES (Lausanne : Frontiers Media S.A., 2014-) pp. - - issn: 2296-889X - wos: WOS:000893554700001 (4) - scopus: 2-s2.0-85121011510 (6)

11573/1571274 - 2021 - Fibrogenic signals persist in DAA-treated HCV patients after sustained virological response
Montaldo, Claudia; Terri, Michela; Riccioni, Veronica; Battistelli, Cecilia; Bordoni, Veronica; D'offizi, Gianpiero; Prado, Maria Giulia; Trionfetti, Flavia; Vescovo, Tiziana; Tartaglia, Eleonora; Strippoli, Raffaele; Agrati, Chiara; Tripodi, Marco - 01a Articolo in rivista
paper: JOURNAL OF HEPATOLOGY (Blackwell Munksgaard:PO Box 2148, Periodicals Department, DK-1016 Copenhagen K Denmark:011 45 33 755913, EMAIL: agentservices@oxon.blackwellpublishing.com, INTERNET: http://www.blackwellmunksgaard.com, Fax: 011 45 77 333377) pp. 1301-1311 - issn: 0168-8278 - wos: WOS:000727375100007 (13) - scopus: 2-s2.0-85114987180 (20)

11573/1550677 - 2021 - Mechanisms of peritoneal fibrosis: focus on immune cells-peritoneal stroma interactions
Terri, Michela; Trionfetti, Flavia; Montaldo, Claudia; Cordani, Marco; Tripodi, Marco; Lopez-Cabrera, Manuel; Strippoli, Raffaele - 01g Articolo di rassegna (Review)
paper: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-3224 - wos: WOS:000639137900001 (44) - scopus: 2-s2.0-85104013369 (48)

11573/1361035 - 2020 - Molecular mechanisms and new therapeutic targets in epithelial to mesenchymal transition (EMT) and fibrosis
Battistelli, Cecilia; Diederich, Marc; Keane, Tj; Sandoval, Pilar; Valente, Sergio; Strippoli, Raffaele - 01m Editorial/Introduzione in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000510209700001 (2) - scopus: 2-s2.0-85078745922 (2)

11573/1394955 - 2020 - Design of first-in-class dual EZH2/HDAC inhibitor: biochemical activity and biological evaluation in cancer cells
Romanelli, Annalisa; Stazi, Giulia; Fioravanti, Rossella; Zwergel, Clemens; Di Bello, Elisabetta; Pomella, Silvia; Perrone, Clara; Battistelli, Cecilia; Strippoli, Raffaele; Tripodi, Marco; Del Bufalo, Donatella; Rota, Rossella; Trisciuoglio, Daniela; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 977-983 - issn: 1948-5875 - wos: WOS:000535281200056 (45) - scopus: 2-s2.0-85087681122 (49)

11573/1435591 - 2020 - Nanomaterials for autophagy-related miRNA-34a delivery in cancer treatment
Sharma, Priyanka; Dando, Ilaria; Strippoli, Raffaele; Kumar, Suresh; Somoza, Alvaro; Cordani, Marco; Tafani, Marco - 01g Articolo di rassegna (Review)
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000560727300001 (16) - scopus: 2-s2.0-85089235691 (15)

11573/1435589 - 2020 - Caveolin1 and YAP drive mechanically induced mesothelial to mesenchymal transition and fibrosis
Strippoli, Raffaele; Sandoval, Pilar; Moreno-Vicente, Roberto; Rossi, Lucia; Battistelli, Cecilia; Terri, Michela; Pascual-Antón, Lucía; Loureiro, Marta; Matteini, Francesca; Calvo, Enrique; 9, José Antonio Jiménez-Heffernan; José Gómez 10, Manuel; Jiménez-Jiménez, Victor; Sánchez-Cabo, Fátima; Vázquez, Jesús; Tripodi, Marco; López-Cabrera, Manuel; Ángel Del Pozo, Miguel - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000579809200002 (32) - scopus: 2-s2.0-85089528848 (32)

11573/1364390 - 2020 - Novel quinoline compounds active in cancer cells through coupled DNA methyltransferase inhibition and degradation
Zwergel, C.; Fioravanti, R.; Stazi, G.; Sarno, F.; Battistelli, C.; Romanelli, A.; Nebbioso, A.; Mendes, E.; Paulo, A.; Strippoli, R.; Tripodi, M.; Pechalrieu, D.; Arimondo, P. B.; De Luca, T.; Del Bufalo, D.; Trisciuoglio, D.; Altucci, L.; Valente, S.; Mai, A. - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000522477300193 (7) - scopus: 2-s2.0-85079504263 (7)

11573/1308040 - 2019 - TGFβ impairs HNF1α functional activity in Epithelial-to-Mesenchymal Transition interfering with the recruitment of CBP/p300 acetyltransferases
Bisceglia, Francesca; Battistelli, Cecilia; Noce, Valeria; Montaldo, Claudia; Zammataro, Agatino; Strippoli, Raffaele; Tripodi, Marco; Amicone, Laura; Marchetti, Alessandra - 01a Articolo in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000483322300001 (8) - scopus: 2-s2.0-85070663914 (9)

11573/1308175 - 2019 - Interplay between ROS and Autophagy in Cancer and Aging: From Molecular Mechanisms to Novel Therapeutic Approaches
Cordani, Marco; Donadelli, Massimo; Strippoli, Raffaele; Bazhin, Alexandr V.; Sánchez-Álvarez, Miguel - 01m Editorial/Introduzione in rivista
paper: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (London: Hindawi AUSTIN, USA, TX: LANDES BIOSCIENCE) pp. 1-3 - issn: 1942-0900 - wos: WOS:000481942900001 (27) - scopus: 2-s2.0-85071746655 (32)

11573/1680928 - 2019 - In vivo Bioluminescence-Based Monitoring of Liver Metastases from Colorectal Cancer: An Experimental Model
Magistri, Paolo; Battistelli, Cecilia; Toietta, Gabriele; Strippoli, Raffaele; Sagnotta, Andrea; Forgione, Antonello; Di Benedetto, Fabrizio; Uccini, Stefania; Vittorioso, Paola; D'angelo, Francesco; Aurello, Paolo; Ramacciato, Giovanni; Nigri, Giuseppe - 01a Articolo in rivista
paper: JOURNAL OF MICROSCOPY AND ULTRASTRUCTURE (Elsevier B.V.) pp. 136-140 - issn: 2213-879X - wos: (0) - scopus: 2-s2.0-85095753295 (4)

11573/1321281 - 2019 - YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation
Noce, Valeria; Battistelli, Cecilia; Cozzolino, Angela Maria; Consalvi, Veronica; Cicchini, Carla; Strippoli, Raffaele; Tripodi, Marco; Marchetti, Alessandra; Amicone, Laura - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000490001800007 (23) - scopus: 2-s2.0-85073113246 (24)

11573/1630492 - 2019 - Erratum: Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP (Cell Reports (2018) 25(6) (1622–1635.e6), (S2211124718316000) (10.1016/j.celrep.2018.10.024))
R., Moreno-Vicente; D. M., Pavon; I., Martin-Padura; M., Catala-Montoro; A., Diez-Sanchez; A., Quilez-Alvarez; J. A., Lopez; M., Sanchez-Alvarez; J., Vazquez; Strippoli, Raffaele; M. A., Del Pozo - 01b Commento, Erratum, Replica e simili
paper: CELL REPORTS (Elsevier B.V. Cambridge MA: Cell Press) pp. 1679-1680 - issn: 2211-1247 - wos: WOS:000457709200025 (15) - scopus: 2-s2.0-85060770185 (13)

11573/1208206 - 2019 - Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells
Stazi, Giulia; Battistelli, Cecilia; Piano, Valentina; Mazzone, Roberta; Marrocco, Biagina; Marchese, Sara; Louie, Sharon M.; Zwergel, Clemens; Antonini, Lorenzo; Patsilinakos, Alexandros; Ragno, Rino; Viviano, Monica; Sbardella, Gianluca; Ciogli, Alessia; Fabrizi, Giancarlo; Cirilli, Roberto; Strippoli, Raffaele; Marchetti, Alessandra; Tripodi, Marco; Nomura, Daniel K.; Mattevi, Andrea; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 722-735 - issn: 0223-5234 - wos: WOS:000458597300053 (15) - scopus: 2-s2.0-85058530369 (15)

11573/1298311 - 2019 - Sestrins at the Interface of ROS Control and Autophagy Regulation in Health and Disease
Strippoli, Raffaele; Cordani, Marco; Sánchez-Álvarez, Miguel; Bazhin, M. A. V.; Massimo Donadelli, A. V. - 01g Articolo di rassegna (Review)
paper: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (London: Hindawi AUSTIN, USA, TX: LANDES BIOSCIENCE) pp. - - issn: 1942-0900 - wos: WOS:000468521200001 (46) - scopus: 2-s2.0-85068207878 (49)

11573/1342561 - 2019 - Nanomaterials as Inhibitors of Epithelial Mesenchymal Transition in Cancer Treatment
Strippoli, Raffaele; Cordani, Marco; Somoza, Alvaro - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. 1-41 - issn: 2072-6694 - wos: WOS:000516826700025 (22) - scopus: 2-s2.0-85077209131 (25)

11573/1341464 - 2019 - An Abl-FBP17 mechanosensing system couples local plasma membrane curvature and stress fiber remodeling during mechanoadaptation
Strippoli, Raffaele; Echarri, Asier; Pavón, Dácil M.; Sánchez Perales, Sara; García-García, María; Calvo, Enrique; Huerta-López, Carla; Velázquez-Carreras, Diana; Viaris De Lesegno, Christine; Ariotti, Nicholas; Lázaro-Carrillo, Ana; Sancho, David; Alegre-Cebollada, Jorge; Lamaze, Christophe; Parton, Robert G.; Del Pozo, Miguel A. - 01a Articolo in rivista
paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. 1-16 - issn: 2041-1723 - wos: WOS:000509780300032 (41) - scopus: 2-s2.0-85076882999 (43)

11573/1265927 - 2019 - Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells
Zwergel, Clemens; Schnekenburger, Michael; Sarno, Federica; Battistelli, Cecilia; Manara, Maria Cristina; Stazi, Giulia; Mazzone, Roberta; Fioravanti, Rossella; Gros, Christina; Ausseil, Frédéric; Florean, Cristina; Nebbioso, Angela; Strippoli, Raffaele; Ushijima, Toshikazu; Scotlandi, Katia; Tripodi, Marco; Arimondo, Paola B.; Altucci, Lucia; Diederich, Marc; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. - - issn: 1868-7083 - wos: WOS:000467227900001 (24) - scopus: 2-s2.0-85065468885 (29)

11573/1069660 - 2018 - SMO inhibition modulates cellular plasticity and invasiveness in colorectal cancer
Magistri, Paolo; Battistelli, Cecilia; Strippoli, Raffaele; Petrucciani, Niccolò; Pellinen, Teijo; Rossi, Lucia; Mangogna, Livia Maria; Aurello, Paolo; D'angelo, Francesco; Tripodi, Marco; Ramacciato, Giovanni; Nigri, Giuseppe - 01a Articolo in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. 1-13 - issn: 1663-9812 - wos: WOS:000423986600001 (26) - scopus: 2-s2.0-85041821519 (28)

11573/1202512 - 2018 - Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP
Moreno-Vicente, R; Pavón D., M; Martín-Padura, I.; Català-Montoro, M.; Díez-Sánchez, A.; Quílez-Álvarez, A.; López, J; Sánchez-Álvarez, M; Vázquez, J.; Strippoli, Raffaele; Del Pozo M., A - 01a Articolo in rivista
paper: CELL REPORTS (Elsevier B.V. Cambridge MA: Cell Press) pp. 1622-1635 - issn: 2211-1247 - wos: WOS:000449476500019 (77) - scopus: 2-s2.0-85055751306 (80)

11573/1174358 - 2018 - Role of the endocytosis of caveolae in intracellular signaling and metabolism
Muriel, Olivia; Sánchez-Álvarez, Miguel; Strippoli, Raffaele; Angel Del Pozo, Miguel - 02a Capitolo o Articolo
book: Endocytosis and Signaling - (978-3-319-96704-2)

11573/1069594 - 2018 - ITGB1-dependent upregulation of Caveolin-1 switches TGFβ signalling from tumour-suppressive to oncogenic in prostate cancer
Pellinen, T; Blom, S; Sánchez, S; Välimäki, K; Mpindi, Jp; Azegrouz, H; Strippoli, Raffaele; Nieto, R; Vitón, M5; Palacios, I; Turkki, R; Wang, Y; Sánchez-Alvarez, M; Nordling, S; Bützow, A; Mirtti, T; Rannikko, A; Montoya, Mc; Kallioniemi, O; Del Pozo, Ma1 - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 1-14 - issn: 2045-2322 - wos: WOS:000424087700010 (24) - scopus: 2-s2.0-85041665506 (26)

11573/1017310 - 2018 - Neutralization of IFN-γ reverts clinical and laboratory features in a mouse model of macrophage activation syndrome.
Prencipe, Giusi; Caiello, Ivan; Pascarella, Antonia; Grom, Alexei A.; Bracaglia, Claudia; Chatel, Laurence; Ferlin, Walter G.; Marasco, Emiliano; Strippoli, Raffaele; De Min, Cristina; Fabrizio De Benedetti, And - 01a Articolo in rivista
paper: THE JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (St. Louis, MO : Elsevier) pp. 1439-1449 - issn: 1097-6825 - wos: WOS:000429197800029 (82) - scopus: 2-s2.0-85028933254 (78)

11573/1120934 - 2018 - HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal
Rossi, Lucia; Battistelli, Cecilia; De Turris, Valeria; Noce, Valeria; Zwergel, Clemens; Valente, Sergio; Moioli, Alessandra; Manzione, Andrea; Palladino, Marco; Bordoni, Veronica; Domenici, Alessandro; Mene', Paolo; Mai, Antonello; Tripodi, Marco; Strippoli, Raffaele - 01a Articolo in rivista
paper: OPEN ACCESS SCIENTIFIC REPORTS (Los Angeles, CA : OMICS Publishing Group, [2012]-) pp. - - issn: 2332-2675 - wos: WOS:000433547600053 (22) - scopus: 2-s2.0-85048002226 (25)

11573/1184953 - 2017 - Severe osteoarticular involvement in isotretinoin-triggered acne fulminans: two cases successfully treated with anakinra.
Oranges, Teresa; Insalaco, Antonella; Diociaiuti, A; Carnevale, C; Strippoli, Raffaele; Zambruno, G.; Toma, P.; El Hachem, Maya - 01f Lettera, Nota
paper: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0926-9959 - wos: WOS:000403695600004 (6) - scopus: 2-s2.0-85003481161 (6)

11573/946056 - 2017 - Functional Roles and Therapeutic Applications of Exosomes in Hepatocellular Carcinoma
Santangelo, Laura; Battistelli, Cecilia; Montaldo, Claudia; Citarella, Franca; Strippoli, Raffaele; Cicchini, Carla - 01a Articolo in rivista
paper: BIOMED RESEARCH INTERNATIONAL ([London]: [Hindawi] Cairo: Hindawi Publishing Corporation) pp. - - issn: 2314-6133 - wos: WOS:000394850800001 (24) - scopus: 2-s2.0-85013276849 (26)

11573/924174 - 2017 - Cell-based assays to study ERK pathway/caveolin1 interactions
Strippoli, Raffaele; Echarri, Asier; Del Pozo, Miguel Angel - 02a Capitolo o Articolo
book: Methods in Molecular Biology - (978-1-4939-6422-2; 978-1-4939-6424-6)

11573/924194 - 2016 - TGFbeta induces binucleation/polyploidization in hepatocytes through a src-Dependent cytokinesis failure
De Santis Puzzonia, Marco; Cozzolino, Angela Maria; Grassi, Germana; Bisceglia, Francesca; Strippoli, Raffaele; Guarguaglini, Giulia; Citarella, Franca; Sacchetti, Benedetto; Tripodi, Marco; Marchetti, Alessandra; Amicone, Laura - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e0167158- - issn: 1932-6203 - wos: WOS:000389472400093 (13) - scopus: 2-s2.0-84997426746 (12)

11573/867038 - 2016 - Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis
Strippoli, Raffaele; Moreno Vicente, Roberto; Battistelli, Cecilia; Cicchini, Carla; Noce, Valeria; Amicone, Laura; Marchetti, Alessandra; Del Pozo, Miguel Angel; Tripodi, Marco - 01g Articolo di rassegna (Review)
paper: STEM CELLS INTERNATIONAL (SAGE-Hindawi) pp. - - issn: 1687-9678 - wos: WOS:000373040900001 (104) - scopus: 2-s2.0-84959440932 (113)

11573/957778 - 2015 - Inhibition of natural killer cell cytotoxicity by interleukin-6: Implications for the pathogenesis of macrophage activation syndrome
Cifaldi, Loredana; Prencipe, Giusi; Caiello, Ivan; Bracaglia, Claudia; Locatelli, Franco; De Benedetti, Fabrizio; Strippoli, Raffaele - 01a Articolo in rivista
paper: ARTHRITIS & RHEUMATOLOGY (Malden, MA : Wiley, [2014]-) pp. 3037-3046 - issn: 2326-5191 - wos: WOS:000363881400029 (189) - scopus: 2-s2.0-84946022428 (197)

11573/978657 - 2015 - INHIBITION OF NATURAL KILLER (NK) CELL CYTOTOXICITY BY INTERLEUKIN-6: IMPLICATIONS FOR THE PATHOGENESIS OF MACROPHAGE ACTIVATION SYNDROME (MAS)
De Benedetti, Fabrizio; Cifaldi, Loredana; Prencipe, Giusi; Caiello, Ivan; Bracaglia, Claudia; Strippoli, Raffaele - 04d Abstract in atti di convegno
paper: PEDIATRIC BLOOD & CANCER (Wiley Liss:111 River Street:Hoboken, NY 07030:(201)748-6000, (212)850-6645, EMAIL: subinfo@wiley.com, INTERNET: http://www.wiley.co.uk, Fax: (201)748-6088) pp. 5S-5S - issn: 1545-5009 - wos: WOS:000351680100021 (0) - scopus: (0)

11573/1630504 - 2015 - Erratum to Caveolin-1 deficiency induces a MEK-ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis [EMBO Mol Med (2015) 7: 102-123]. DOI 10.15252/emmm.201404127
Strippoli, R.; Loureiro, J.; Moreno, V.; Benedicto, I.; Lozano, M. L. P.; Barreiro, O.; Pellinen, T.; Minguet, S.; Foronda, M.; Osteso, M. T.; Calvo, E.; Vazquez, J.; Cabrera, M. L.; Del Pozo, M. A. - 01b Commento, Erratum, Replica e simili
paper: EMBO MOLECULAR MEDICINE (Chichester : Wiley-Blackwell, 2009-) pp. 357-357 - issn: 1757-4676 - wos: WOS:000350767600010 (16) - scopus: 2-s2.0-84929716505 (0)

11573/978640 - 2015 - S100A12 as diagnostic tool in the differential diagnosis of sJIA associated MAS vs. hereditary or acquired HLH
Strippoli, Raffaele - 04d Abstract in atti di convegno
paper: PEDIATRIC RHEUMATOLOGY ONLINE JOURNAL ([Chicago. Ill. : University of Chicago, 2003]-) pp. - - issn: 1546-0096 - wos: (0) - scopus: 2-s2.0-84956846830 (1)
conference: 8th International Congress of Familial Mediterranean Fever and Systemic Autoinflammatory Diseases (Dresden; Germany)
book: Pediatric Rheumatology online journal - ()

11573/639013 - 2015 - Caveolin-1 deficiency induces a MEK-ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis
Strippoli, Raffaele; Jesús, Loureiro; Vanessa, Moreno; Ignacio, Benedicto; María Luisa Pérez, Lozano; Olga, Barreiro; Teijo, Pellinen; Susana, Minguet; Miguel, Foronda; Maria Teresa, Osteso; Enrique, Calvo; Jesús, Vázquez; Manuel López, Cabrera; Miguel Angel Del, Pozo - 01a Articolo in rivista
paper: EMBO MOLECULAR MEDICINE (Chichester : Wiley-Blackwell, 2009-) pp. 102-123 - issn: 1757-4676 - wos: WOS:000347339600008 (62) - scopus: 2-s2.0-84925331493 (78)

11573/978661 - 2014 - Inhibition of Natural Killer (NK) Cell Cytotoxicity By Interleukin-6 (IL-6): Implications for the Pathogenesis of Macrophage Activation Syndrome
Cifaldi, L.; Prencipe, ; G., Caiello; I., Bracaglia; Strippoli, Raffaele; R., De Benedetti - 04d Abstract in atti di convegno
paper: ARTHRITIS & RHEUMATOLOGY (Malden, MA : Wiley, [2014]-) pp. S133-S133 - issn: 2326-5191 - wos: WOS:000344384900311 (0) - scopus: (0)

11573/558494 - 2014 - Nerve Growth Factor Downregulates Inflammatory Response in Human Monocytes through TrkA
G., Prencipe; G., Minnone; Strippoli, Raffaele; L., De Pasquale; S., Petrini; I., Caiello; L., Manni; F., De Benedetti; L., Bracci Laudiero - 01a Articolo in rivista
paper: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 3345-3354 - issn: 0022-1767 - wos: WOS:000333342800043 (82) - scopus: 2-s2.0-84897555497 (86)

11573/606181 - 2014 - IL-6 Amplifies TLR Mediated Cytokine and Chemokine Production: Implications for the Pathogenesis of Rheumatic Inflammatory Diseases
Ivan, Caiello; Gaetana, Minnone; Dirk, Holzinger; Thomas, Vogl; Giusi, Prencipe; Antonio, Manzo; Fabrizio De, Benedetti; Strippoli, Raffaele - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. ....----- - issn: 1932-6203 - wos: WOS:000343729600023 (51) - scopus: 2-s2.0-84907546570 (53)

11573/576384 - 2014 - Advances toward hepatic tissue engineering
Tripodi, Marco; A. M., Cozzolino; V., Costa; Conigliaro, Alice; Battistelli, Cecilia; Strippoli, Raffaele; Cicchini, Carla; Amicone, Laura - 04c Atto di convegno in rivista
paper: JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (Chichester, West Sussex, UK : John Wiley & Sons) pp. 8 (Suppl. 1): 6--8 (Suppl. 1): -38. - issn: 1932-6254 - wos: WOS:000337612600069 (0) - scopus: (0)
conference: Keynote Presentations ()

11573/559832 - 2013 - Monocytes and macrophages as biomarkers for the diagnosis of megalencephalic leukoencephalopathy with subcortical cysts.
Petrini, S; Minnone, G; Coccetti, M; Frank, C; Aiello, C; Cutarelli, A; Ambrosini, E; Lanciotti, A; Brignone, Ms; D'oria, V; Strippoli, Raffaele; De Benedetti, F; Bertini, E; Bracci Laudiero, L. - 01a Articolo in rivista
paper: MOLECULAR AND CELLULAR NEUROSCIENCES (Attuale:ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, USA, CA, 92101-4495 Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 307-321 - issn: 1044-7431 - wos: WOS:000325834100029 (18) - scopus: 2-s2.0-84881239605 (15)

11573/559831 - 2013 - Reaching the threshold: a multilayer pathogenesis of macrophage activation syndrome.
Strippoli, Raffaele; Caiello, I; De Benedetti, F. - 01a Articolo in rivista
paper: THE JOURNAL OF RHEUMATOLOGY (Journal of Rheumatology:920 Yonge Street, Suite 115, Toronto Ontario M4W 3C7 Canada:(416)967-5155, EMAIL: jrheum@inforamp.com, INTERNET: http://jrheum.com, Fax: (416)967-7556) pp. 761-767 - issn: 0315-162X - wos: WOS:000320009600005 (59) - scopus: 2-s2.0-84878666042 (60)

11573/559811 - 2012 - Inhibition of Transforming Growth Factor-Activated Kinase 1 (TAK1) Blocks and Reverses Epithelial to Mesenchymal Transition of Mesothelial Cells
Strippoli, Raffaele; Benedicto, I; Perez Lozano M., L; Pellinen, T; Sandoval, P; Lopez Cabrera, M; Del Pozo, M. A. - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. - - issn: 1932-6203 - wos: WOS:000302918500027 (40) - scopus: 2-s2.0-84857510902 (45)

11573/559824 - 2012 - Amplification of the response to toll-like receptor ligands by prolonged exposure to interleukin-6 in mice: Implication for the pathogenesis of macrophage activation syndrome
Strippoli, Raffaele; Carvello, F; Scianaro, R; De Pasquale, L; Vivarelli, M; Petrini, S; Bracci Laudiero, L; De Benedetti, F. - 01a Articolo in rivista
paper: ARTHRITIS AND RHEUMATISM (Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320) pp. 1680-1688 - issn: 0004-3591 - wos: WOS:000303239000042 (85) - scopus: 2-s2.0-84860458850 (88)

11573/577787 - 2011 - The Anti-Inflammatory Action of Nerve Growth Factor Is Mediated by Trka Signalling: Modification in Trka Expression in Juvenile Idiopathic Arthritis Mononuclear Cells Create An Unbalance Between Inflammatory and Anti-Inflammatory Pathways?
Minnone, G; Prencipe, G; Strippoli, Raffaele; De Pasquale, L; Caiello, I; De Benedetti, F; Bracci Laudiero, L. - 04c Atto di convegno in rivista
paper: ARTHRITIS AND RHEUMATISM (Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320) pp. - - issn: 0004-3591 - wos: WOS:000297621501180 (0) - scopus: (0)

11573/577783 - 2011 - Nerve Growth Factor, Acting Through TrkA, Down-Regulates the Inflammatory Response in Human Monocytes After Toll-Like Receptor Stimulation.
Prencipe, G; Minnone, G; Strippoli, Raffaele; De Pasquale, L; De Benedetti, F; Bracci Laudiero, L. - 04c Atto di convegno in rivista
paper: NEUROIMMUNOMODULATION (S Karger AG:Allschwilerstrasse 10, CH-4009 Basel Switzerland:011 41 61 3061111, EMAIL: orders@karger.ch, INTERNET: http://www.karger.com, Fax: 011 41 61 3061234) pp. - - issn: 1021-7401 - wos: WOS:000295788700108 (1) - scopus: (0)

11573/577795 - 2011 - Cross-talk between signals induced by IL-6 and TLR ligands causes increased inflammatory response in mouse and human macrophages. Implication for macrophage activation syndrome
Strippoli, Raffaele; Carvello, F; De Pasquale, L; De Vito, R; Bracci Laudiero, L; De Benedetti, F. - 04c Atto di convegno in rivista
paper: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY (Clinical and Experimental Rheumatology:Via S Maria 31, I 56126 Pisa Italy:011 39 050 40124, EMAIL: info@clinexprhematol.org, INTERNET: http://www.clinexprhematol.org, Fax: 011 39 050 502299) pp. - - issn: 0392-856X - wos: WOS:000290703100073 (0) - scopus: (0)

11573/559789 - 2010 - p38 maintains E-cadherin expression by modulating TAK1-NF-kappa B during epithelial-to-mesenchymal transition
Strippoli, Raffaele; Benedicto, I; Foronda, M; Luisa Perez Lozano, M; Sanchez Perales, S; Lopez Cabrera, M; Del Pozo, M. A. - 01a Articolo in rivista
paper: JOURNAL OF CELL SCIENCE (The Company of Biologists Limited:Bidder Building, 140 Cowley Road, Cambridge CB4 0DL United Kingdom:011 44 1223 420482, EMAIL: mandy@thecob.demon.co.uk, INTERNET: http://www.biologists.com, Fax: 011 44 1223 423353) pp. 4321-4331 - issn: 0021-9533 - wos: WOS:000284837100014 (74) - scopus: 2-s2.0-78649746810 (78)

11573/559788 - 2009 - Targeting the ERK/NF-κB/Snail1 pathway as a potential therapeutic strategy to prevent the failure of peritoneal dialysis
Strippoli, Raffaele; Foronda, M; Lopez Cabrera, M; Del Pozo, M. A. - 01a Articolo in rivista
paper: NATURE REVIEWS. CARDIOLOGY () pp. 43-48 - issn: 1759-5002 - wos: (0) - scopus: (0)

11573/559813 - 2008 - Epithelial-to-mesenchymal transition of peritoneal mesothelial cells is regulated by an ERK/NF-kappa B/Snail1 pathway
Strippoli, Raffaele; Benedicto, I; Perez Lozano M., L; Cerezo, A; Lopez Cabrera, M; Del Pozo, M. A. - 01a Articolo in rivista
paper: DISEASE MODELS & MECHANISMS (Cambridge : Company of Biologists, 2007-) pp. 264-274 - issn: 1754-8403 - wos: WOS:000268254400015 (101) - scopus: 2-s2.0-64249143248 (107)

11573/47987 - 2006 - HIV-1 Tat regulates endothelial cell cycle progression via activation of the Ras/ERK MAPK signaling pathway
E., Toschi; I., Bacigalupo; Strippoli, Raffaele; C., Chiozzini; A., Cereseto; M., Falchi; F., Nappi; C., Sgadari; G., Barillari; Mainiero, Fabrizio; B., Ensoli - 01a Articolo in rivista
paper: MOLECULAR BIOLOGY OF THE CELL (The American Society for Cell Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7153, Fax: (301)571-8304) pp. 1985-1994 - issn: 1059-1524 - wos: WOS:000236657900044 (61) - scopus: 2-s2.0-33745398365 (64)

11573/559791 - 2005 - Inhibition of interleukin-8 (CXCL8/IL-8) responses by repertaxin, a new inhibitor of the chemokine receptors CXCR1 and CXCR2
Casilli, F; Bianchini, A; Gloaguen, I; Biordi, L; Alesse, E; Festuccia, C; Cavalieri, B; Strippoli, Raffaele; Cervellera, Mn; Di Bitondo, R; Ferretti, Elisabetta; Bizzarri, C; Colotta, F; Bertini, R.; Mainiero, Fabrizio - 01a Articolo in rivista
paper: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited -London ; New York : Pergamon Press, 1958-) pp. 385-394 - issn: 0006-2952 - wos: WOS:000226699800003 (86) - scopus: 2-s2.0-19944429545 (96)

11573/47853 - 2005 - Constitutive activation of p38 and ERK1/2 MAPKs in epithelial cells of myasthenic thymus leads to IL-6 and RANTES overexpression: Effects on survival and migration of peripheral T and B cells
M., Colombara; V., Antonini; A. P., Riviera; Mainiero, Fabrizio; Strippoli, Raffaele; M., Merola; G., Fracasso; O., Poffe; N., Brutti; G., Tridente; M., Colombatti; D., Ramarli - 01a Articolo in rivista
paper: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 7021-7028 - issn: 0022-1767 - wos: WOS:000233126300091 (33) - scopus: 2-s2.0-27744547953 (35)

11573/235342 - 2004 - Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury.
Bertini, R; Allegretti, M; Bizzarri, C; Moriconi, A; Locati, M; Zampella, G; Cervellera, Mn; Di Cioccio, V; Cesta, Mc; Galliera, E; Martinez, Fo; Di Bitondo, R; Troiani, G; Sabbatini, V; D'anniballe, G; Anacardio, R; Cutrin, Jc; Cavalieri, B; Mainiero, Fabrizio; Strippoli, Raffaele; Villa, P; Di Girolamo, M; Martin, F; Gentile, M; Santoni, Angela; Corda, D; Poli, G; Mantovani, A; Ghezzi, P; Colotta, F. - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 11791-11796 - issn: 0027-8424 - wos: WOS:000223276700048 (286) - scopus: 2-s2.0-4143050328 (296)

11573/389017 - 2004 - Constitutive activation of mitogen activated protein kinase (MAPK) leads to IL-6 and Rantes over-production in thymic epithelial cells (TEC) of patients with myasthenia gravis (MG)
Colombara, M; Antonini, V; Riviera, Ap; Strippoli, Raffaele; Merola, M; Poffe, O; Tridente, G; Mainiero, Fabrizio; Ramarli, D. - 04b Atto di convegno in volume
conference: 12th Annual International Congress of Immunology/4th Annual Conference of the Federation-of-Clinical-Immunology-Societies (FOCIS) (Montreal, CANADA)

11573/62868 - 2004 - Activation of p38-MAP-Kinase and not of caspases in human leukemic cells stimulated by monensin: a distincy pathway from those of TNF-induced and receptor-mediated apoptosis
Parente, R; Trifiro, E; Strippoli, Raffaele; Mainiero, F; Di Renzo, Livia Maria - 04d Abstract in atti di convegno
book: Convegno della Associazione di Biologia Cellulare e del Differenziamento - ()

11573/240398 - 2004 - Key role of proline-rich tyrosine kinase 2 in interleukin-8 (CXCL8/IL-8)-mediated human neutrophil chemotaxis
Vito Di, Cioccio; Strippoli, Raffaele; Cinzia, Bizzarri; Giulia, Troiani; Maria Neve, Cervellera; Isabelle, Gloaguen; Antonella, Colagrande; Elisa Margherita, Cattozzo; Sabrina, Pagliei; Santoni, Angela; Francesco, Colotta; Mainiero, Fabrizio; Riccardo, Bertini - 01a Articolo in rivista
paper: IMMUNOLOGY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 407-415 - issn: 0019-2805 - wos: WOS:000220547100008 (42) - scopus: 2-s2.0-11144357291 (43)

11573/250554 - 2003 - Proline-rich tyrosine kinase 2 and Rac activation by chemokine and integrin receptors controls NK cell transendothelial migration
Gismondi, Angela; J., Jacobelli; Strippoli, Raffaele; Mainiero, Fabrizio; Soriani, Alessandra; Loredana, Cifaldi; Piccoli, Mario; Frati, Luigi; Santoni, Angela - 01a Articolo in rivista
paper: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 3065-3073 - issn: 0022-1767 - wos: WOS:000181412500037 (49) - scopus: 2-s2.0-0037443465 (52)

11573/47807 - 2003 - p38 MAPK is a critical regulator of the constitutive and the beta4 integrin-regulated expression of IL-6 in human normal thymic epithelial cells.
Mainiero, Fabrizio; Michaela, Colombara; Valeria, Antonini; Strippoli, Raffaele; Marcello, Merola; Ornella, Poffe; Giuseppe, Tridente; Dunia, Ramarli - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF IMMUNOLOGY (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 3038-3048 - issn: 0014-2980 - wos: WOS:000186450200010 (31) - scopus: 2-s2.0-0242391992 (31)

11573/559809 - 2001 - In vitro activity of propyl gallate-azole drug combination against fluconazole- and itraconazole-resistant Candida albicans strains
D'auria, Fd; Tecca, M; Strippoli, Raffaele; Simonetti, N. - 01a Articolo in rivista
paper: LETTERS IN APPLIED MICROBIOLOGY (Oxford: Blackwell Scientific Limited) pp. 220-223 - issn: 0266-8254 - wos: WOS:000167955100002 (15) - scopus: 2-s2.0-0035068253 (20)

11573/577800 - 2001 - Role of Pyk2 in the control of human NK cell migration
Gismondi, Angela; Jacobelli, J; Mainiero, Fabrizio; Strippoli, Raffaele; Santoni, Angela - 04c Atto di convegno in rivista
paper: THE FASEB JOURNAL (Federation of American Societies for Experimental Biology (FASEB):9650 Rockville Pike, Room L-2310:Bethesda, MD 20814:(800)433-2732, (301)530-7027, EMAIL: staff@dues.faseb.org, INTERNET: http://www.faseb.org, Fax: (301)571-5728, (301)530-7001) pp. A331-A331 - issn: 0892-6638 - wos: WOS:000167438101889 (0) - scopus: (0)

11573/385169 - 2001 - Integrin-mediated p38 MAPK activation controls chemokine production by human NK cells
Mainiero, Fabrizio; Soriani, Alessandra; Strippoli, Raffaele; Gismondi, Angela; Jacobelli, J; Santoni, Angela - 04d Abstract in atti di convegno
paper: THE FASEB JOURNAL (Federation of American Societies for Experimental Biology (FASEB):9650 Rockville Pike, Room L-2310:Bethesda, MD 20814:(800)433-2732, (301)530-7027, EMAIL: staff@dues.faseb.org, INTERNET: http://www.faseb.org, Fax: (301)571-5728, (301)530-7001) pp. - - issn: 0892-6638 - wos: WOS:000167438101904 (0) - scopus: (0)

11573/559787 - 2000 - Integrine e cellule Natural Killer (NK)
Mainiero, F; Gismondi, A; Strippoli, Raffaele; Soriani, Alessandra; Jacobelli, J; Santoni, A. - 01a Articolo in rivista
paper: EOS (Rome Italy: Sigma Tau) pp. 71-76 - issn: 0392-6699 - wos: (0) - scopus: 2-s2.0-0034469175 (0)

11573/250609 - 2000 - Integrin-mediated regulation of cytokine and chemokine production by human natural killer cells
Mainiero, Fabrizio; Gismondi, Angela; Strippoli, Raffaele; J., Jacobelli; Soriani, Alessandra; Morrone, Stefania; Santoni, Angela - 04c Atto di convegno in rivista
paper: EUROPEAN CYTOKINE NETWORK (John Libby Eurotext Ltd:127 avenue de la Republique, F 92120 Montrouge France:011 33 1 46730660, EMAIL: marketing@jle.com, INTERNET: http://www.john-libbey-eurotext.fr, Fax: 011 33 1 40840999) pp. 493-494 - issn: 1148-5493 - wos: WOS:000090108700024 (5) - scopus: 2-s2.0-0034263447 (5)
conference: 2nd Joint Workshop on Cytokines in Inflammation on the Occasion of Hans-Dieter Flads Retirement (LUBECK, GERMANY)

11573/255949 - 2000 - RAC1/P38 MAPK signaling pathway controls beta1 integrin-induced interleukin-8 production in human natural killer cells.
Mainiero, Fabrizio; Soriani, Alessandra; Strippoli, Raffaele; Jacobelli, J.; Gismondi, Angela; Piccoli, Mario; Frati, Luigi; Santoni, Angela - 01a Articolo in rivista
paper: IMMUNITY (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 7-16 - issn: 1074-7613 - wos: WOS:000085011900002 (83) - scopus: 2-s2.0-0033959736 (87)

11573/577797 - 1999 - Beta 1 integrin ligation induce cytokine and chemokine expression in human NK cells
Mainiero, Fabrizio; Soriani, Alessandra; Jacobelli, J; Strippoli, Raffaele; Gismondi, Angela; Morrone, Stefania; Santoni, Angela - 04c Atto di convegno in rivista
paper: THE FASEB JOURNAL (Federation of American Societies for Experimental Biology (FASEB):9650 Rockville Pike, Room L-2310:Bethesda, MD 20814:(800)433-2732, (301)530-7027, EMAIL: staff@dues.faseb.org, INTERNET: http://www.faseb.org, Fax: (301)571-5728, (301)530-7001) pp. A962-A962 - issn: 0892-6638 - wos: WOS:000082132901821 (0) - scopus: (0)

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