Dottorato in FARMACOLOGIA E TOSSICOLOGIA

email: patrizia.campolongo@uniroma1.it
telefono: 0649912450
edificio: CU024
stanza: 3

CURRICULUM DIDATTICO-SCIENTIFICO DELLA PROF.SSA PATRIZIA CAMPOLONGO

DATI PERSONALI
Nome e Cognome PATRIZIA CAMPOLONGO
Luogo e data di nascita:
Stato Civile:
Dipartimento
Indirizzo COSENZA 20 MARZO 1977
CONIUGATA (2 FIGLI)
DIPARTIMENTO DI FISIOLOGIA E FARMACOLOGIA “V:ERSPAMER”

P.le ALDO MORO, 5
00185 ROMA

Telefono uff./lab./mobile 06/49912450
339/6626745

Fax 06/49912480

E-mail patrizia.campolongo@uniroma1.it



ATTUALE POSIZIONE
Professore Associato SSD BIO-14, SC 05/G1, Facoltà di Farmacia e Medicina, Dipartimento Fisiologia e Farmacologia “Vittorio Erspamer”, Sapienza Università di Roma.
Junior Fellow - Scuola Superiore di Studi Avanzati Sapienza (2013-2019).
Abilitazione Scientifica Nazionale a Professore di I Fascia per il Settore Concorsuale 05/G1 - Farmacologia, farmacologia clinica e farmacognosia (Bando 2013; DD n. 161/2013) conseguita il 5 novembre 2014.

CARRIERA E TITOLI
Giu 1995 Maturità classica conseguita presso il Liceo Classico B. Telesio di Cosenza con il massimo ei voti
Nov 2001 Laurea in Chimica e Tecnologia Farmaceutiche conseguita presso l’Università degli Studi di Roma “La Sapienza” con il massimo dei voti.
2001/2002 Corso di Perfezionamento in Ecotossicologia presso l’Università degli Studi di Roma “La Sapienza”.
Giu 2002 Abilitazione alla professione di Farmacista conseguita presso l’Università degli Studi di Roma “La Sapienza”.
Nov 2002- Nov 2005 Dottorato di ricerca in Farmacologia, Farmacognosia e Tossicologia (XVIII ciclo). Tesi: “The endocannabinoid system as a new target for the treatment of mood disorders and anxiety”. (Dipartimento di Fisiologia Umana e Farmacologia- Università degli Studi di Roma “La Sapienza) con conseguimento del titolo in data 7 marzo 2006.
Nov 2002-Giu 2004 Attività di ricerca svolta nell’ambito del dottorato di ricerca presso l’Istituto Superiore di Sanità- Sezione di Neuroscienze Comportamentali
Dic 2005- Ott 2008 Assegnista di Ricerca presso il Dipartimento di Scienze Biomediche dell’Università degli Studi di Foggia. Progetto di Ricerca: “Caratterizzazione comportamentale e neurochimica di CHF2819 nel ratto”.
Nov 2008- Giu 2015 Ricercatore Universitario SSD BIO-14 Facoltà di Farmacia, Dipartimento Fisiologia e Farmacologia Vittorio Erspamer, Sapienza Università di Roma

SOGGIORNI DI STUDIO ALL’ESTERO
Giu 2004- Dic 2004; Set 2005- Gen 2006 Junior specialist presso il “Center for the Neurobiology of Learning and Memory”, University of California, Irvine - USA (supervisor Dr. James L McGaugh).
Giu 2013- Sett 2013 Visiting professor presso il “Ludwig Maximilians” University of Munich – Germany.
Aprile 2014 Visiting professor presso Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla.

FINANZIAMENTI RICEVUTI (COME PRINCIPAL INVESTIGATOR)

- Ministero della Salute. (Ricerca finalizzata, 90.000 €). “Don’t cry over spilt (formula) milk: human fMRI correlates of cognitive impairments due to formula feeding and pre-clinical evidence of maternal milk oligosaccharides supplementation as a potential treatment”. (2018-2021). Co-PI
- Ministero dell’Università e della Ricerca Scientifica: PRIN 2015 (57200 €). “Stress in adolescenza: dalle alterazioni cognitive alla suscettibilità per le patologie psichiatriche.” (2015-2018). Responsabile Unità.
- Human Frontier Science Program. Young investigator grant (750000 USD). “Neuroscience meets nanotechnology: the key to unlock emotional memories with nanodetectors” (2012-2015). International coordinator and PI.
- Ministero dell’Università e della Ricerca Scientifica: PRIN 2010-2011 (144826 €), “Ruolo emergente del sistema degli endocannabinoidi nelle malattie neuropsichiatriche” (2012-2015). Responsabile Unità.
- Ministero dell’Università e della Ricerca Scientifica: FIRB, Programma “FUTURO IN RICERCA” (365000 €), titolo “Disturbo post traumatico da stress in età evolutiva: dalla caratterizzazione di processi neurobiologici e fattori di vulnerabilità allo sviluppo di nanotecnologie per applicazioni terapeutiche” (2011-2014). Responsabile Unità.
- Finanziamento FARI, Sapienza Univesrità di Roma (7000 €), titolo “Neural underpinnings of emotional memory processing in rats” (2012).
- Ateneo Italo Tedesco e Società Italiana di Farmacologia. Funding for conference organization. (16500 €). Titolo “The emotional brain: from neurobiology to new therapeutic opportunities. 2011. Chair and organizer of the meeting: Patrizia Campolongo
-Progetti di Ricerca, Sapienza Università di Roma. (15000 €), titolo “The endocannabinoid system as a new target for the treatment of Post Traumatic Stress Disorder” (2011-2012).
- VIGONI 2010-2012, Ateneo Italo Tedesco (5000 €). The program aims at developing a bi-national network dedicated to scientific cooperation between Italy and Germany. Titolo “Neurobiological mechanisms underlying the effects of clinically used sedative drugs on memory consolidation”. Principal investigator (Italia): Patrizia Campolongo. Principal investigator (Germania): Gustav Schelling.
-Progetti di Ricerca, Università di Roma La Sapienza. 13500 €, titolo “Amygdala role in the consolidation of emotional memory processing”. (2010-2011)
-AO-07-CONCORDIA. European Space Agency (ESA, 2009-2012) 250000 €. Titolo: Consequences of Long term-Confinement and Hypobaric Hypoxia on Immunity in the Antarctic Concordia Environment” (CHOICE Study). This large study (including more than 10 international institutions, such as NASA, ESA etc.) investigates the long-term effects of confinement in the Antarctic environment on physiological parameters and neurobiological systems. Co-PI: Patrizia Campolongo.

Oltre ai finanziamenti ricevuti come Principal Investigator, la Prof.ssa Campolongo è stata o è attualmente partecipante di numerosi progetti di ricerca (FIRB e PRIN del Ministero dell’Istruzione e della Ricerca; Doping del Minsitero della Salute, Progetti di Ateneo e di Facoltà della Sapienza Università di Roma, etc.)

PREMI E BORSE DI STUDIO

Premi
- Premio per “Visiting Professors” in Germania (Centro Tedesco per lo Scambio Accademico, DAAD 2013)
- EBBS (European Brain and Behavior Society) Young investigator award 2011
- Premio "Sapienza Ricerca 2010", destinato dall'Università “La Sapienza” ai 6 migliori ricercatori che fanno attività di ricerca di eccellenza all'interno dell'intera Università per la ricerca dal titolo “Il sistema endocannabinoide come possibile target per lo sviluppo di approcci terapeutici innovativi nel trattamento del disturbo post-traumatico da stress”
- Premio Bertè per il miglior lavoro scientifico pubblicato in campo farmacologico nel 2009
- Premio per il miglior progetto di ricerca da realizzarsi in Italia riservata a giovani non strutturati di età inferiore o uguale ai 30 anni erogata dalla Società Italiana di Farmacologia (2005)
- Premio “Nunzio Pascale” (2004)

- Riconoscimenti
- Attestato di Merito per particolari meriti e riconoscimenti di carattere professionale e scientifico per ex-Dottorandi di Sapienza Università di Roma (2014);
Borse di Studio
- Borsa di cofinanziamento per il rinnovo dell’assegno di ricerca erogata dalla Società Italiana di Farmacologia (2007);
- Borsa di ricerca per soggiorni di studio all’estero erogata dalla Società Italiana di Farmacologia (2004);
- 5 borse di studio di durata annuale per studenti universitari fuori sede erogate per merito dall’ADISU –Azienda regionale per il Diritto allo Studio Universitario dell’Università di Roma “La Sapienza” (1996-2000);


ATTIVITA’ DIDATTICA

Insegnamenti come titolare del Corso e Presidente della Commissione d’esame- Italia:

a.a. 2017-2018 ad oggi Insegnamento di Farmacologia Speciale e Farmacoterapia (SSD BIO/14) del Corso di Laurea Magistrale in Farmacia canale M-Z (10 CFU). Sapienza Università di Roma
a.a. 2015-2016 ad oggi Insegnamento di Farmacologia Generale e Molecolare (SSD BIO/14) del Corso di Laurea Magistrale in Farmacia canale M-Z (6 CFU). Sapienza Università di Roma
a.a. 2013-2014 ad a.a. 2016-2017 Insegnamento di Tossicologia (SSD BIO/14) del Corso di Laurea Specialistica in Farmacia DM 270/04 canale A-L (12 CFU). Sapienza Università di Roma
a.a. 2010-2011- 2012-2013 Insegnamento di Tossicologia (SSD BIO/14) del Corso di Laurea Specialistica in Farmacia DM 509/99 canale A-Z (10 CFU). Sapienza Università di Roma
a.a. 2009-2010 Insegnamento di Tossicologia (SSD BIO/14) del Corso di Laurea Specialistica in Biotecnologie Farmaceutiche (4 CFU). Sapienza Università di Roma

Corsi di Specializzazione e di Dottorato
a.a. 2013-2014 ad oggi Corso di Sperimentazione Animale per il Corso di Dottorato in Farmacologia e Tossicologia, Sapienza Università di Roma
a.a. 2011-2012 ad oggi Insegnamenti di: 1) Terapie delle malattie del Sistema Nervoso Centrale: Aspetti Farmacoterapeutici I (SSD BIO/14) e di 2) Farmacoterapia e Farmacogenetica (SSD BIO/14) della Scuola di Specializzazione in Farmacia Ospedaliera, Sapienza Università di Roma
a.a. 2010-2011 Insegnamento di Farmacoterapia basata sulle evidenze della Scuola di Specializzazione in Farmacia Ospedaliera, Sapienza Università di Roma

Insegnamenti come titolare del Corso - Estero:
a.a. 2012-2013 Graduate School of Medicine. University of Munich Germany. Pharmaco-toxicology of anesthetic drugs and substances of abuse. Mobility program for Erasmus Teaching Program a.a. 2012-2013

Ulteriori attività scientifico/didattica:


2013 Faculty member of the Fens-IBRO School Synaptic stress and pathogenesis of neuropsychiatric disorders. Bertinoro, Italy
2012- ad oggi Promotore Accordo bilaterale Erasmus/ per mobilità docenti e studenti in uscita ed entrata tra Sapienza, Università di Roma e “Ludwig-Maximilians University” di Monaco di Baviera, Germania (promotore tedesco Prof. Gustav Schelling).
2009- ad oggi Docente guida dei Dottori/Dottorandi Patrizia Ratano, Maria Morena, Caterina Michetti, Andrea Berardi Dottorato in Farmacologia e Tossicologia, Sapienza Università di Roma.
2008- ad oggi Relatore di molteplici tesi compilative e sperimentali nell’ambito di Corsi di Laurea della Facoltà di Farmacia e Medicina, Sapienza Università di Roma

ATTIVITA’ ISTITUZIONALI, ORGANIZZATIVE E DI SERVIZIO

2008-ad oggi Membro del Collegio dei Docenti del Corso di Dottorato in Farmacologia e Tossicologia della Sapienza Università di Roma
2011-ad oggi Membro del Collegio dei Docenti della Scuola di Specializzazione in Farmacia Ospedaliera della Sapienza Università di Roma
2017 – ad oggi Council member and vicetreasurer della Mediterannean Neuroscience Society
2012-mag 2015 Membro della Commissione Programmazione del Dipartimento di Fisiologia e Farmacologia della Sapienza Università di Roma
2014 ad oggi Responsabile del benessere animale dello stabulario di Farmacologia del Dipartimento di Fisiologia e Farmacologia della Sapienza Università di Roma
2014 ad oggi Membro e Segretario dell’Organismo Preposto al Benessere Animale (OPBA) del Dipartimento di Fisiologia e Farmacologia della Sapienza Università di Roma
2015- 2016 Membro della Commissione Grandi Attrezzature della Sapienza Università di Roma
2015-2017 Membro della Commissione per gli Esami di Stato per lìAbilitazione alla professione di Farmacista



ATTIVITA’ SCIENTIFICA
- Patrizia Campolongo svolge la propria attività di ricerca nel campo della Neuropsicofarmacologia. In particolare la sua attività di ricerca è volta a chiarire come diversi sistemi neurotrasmettioriali, con focus principale sul sistema endocannabinoide, operino nel controllo di processi emozionali e nella formazione di ricordi a forte valenza emotiva. I suoi studi indicano come il sistema endocannabinoide svolga un ruolo primario nella modulazione del consolidamento, del richiamo e dell’estinzione della memoria di eventi emotivamente salienti. Il consolidamento della memoria è un processo fisiologico essenziale: l’uomo, infatti, non sarebbe in grado di sopravvivere se non fosse in grado di ricordare. Esistono tuttavia numerosi disturbi psichiatrici che derivano da alterazioni patologiche di processi cognitivi, fra cui il disturbo post-traumatico da stress. I meccanismi patogenetici alla base di tali disturbi non sono ad oggi stati chiariti. La ricerca della Prof.ssa Campolongo ha lo scopo di delucidare i meccanismi patogenetici associati a tali disturbi. In particolare, negli ultimi anni la ricerca della Prof.ssa Campolongo è stata volta a chiarire quale sia il ruolo di vari sistemi neurobiologici nel regolare la memoria di eventi stressanti/traumatici allo scopo di sviluppare a livello preclinico approcci terapeutici innovativi per il trattamento di disturbi cognitivi correlati allo stress quale il disturbo da stress post-traumatico (PTSD)
Collaborazione con Istituti e Dipartimenti italiani ed esteri:
 University of California, Irvine, USA (James L McGaugh, PhD)
 Radboud University Medical Center, Nijmegen, The Netherlands (Benno Roozendaal, PhD)
 Ludwig Maximilians University, Munich, Germany (Gustav Schelling, MD PhD)
 Hotchkiss Brain Institute. University of Calgary. Canada. (Matthew Hill, PhD)
 Achucarro Basque Center for Neuroscience. Bilbao, Spain. (Mazahir Hasan, PhD)
 Dept. Of Biology University RomaTre, Rome, Italy (Viviana Trezza, PhD)

La Prof.ssa Campolongo oltre ad avere instaurato prestigiose collaborazioni internazionali è inoltre promotore di un Accordo bilaterale Erasmus/LPP per mobilità docenti e studenti in uscita ed entrata tra Sapienza, Università di Roma e “Ludwig-Maximilians University” di Monaco di Baviera, Germania (promotore tedesco Prof. Gustav Schelling).
La Prof.ssa Campolongo è membro del Topical Team “Stress Challenges and Immunity in Space” della “European Space Agency (ESA)”.

PRESENTAZIONI ORALI SU INVITO

1. Campolongo P. Arousal and stress effects on cannabinoid modulation of memory. 11th FENS forum, Berlin 7-11 July (Germany)
2. Campolongo P. The modulatory role of the endocannabinoid system on the consolidation and retrieval of memory for stressful experiences in rats. International Behavioral Neuroscience Society (IBNS) 27th Annual Meeting. 27 June – 2 July 2018. Boca Raton Resort. Florida. USA
3. Campolongo P. Arousal and stress effects on cannabinoid modulation of memory for emotionally arousing experiences. Center for Neurobiology of Learning and Memory spring meeting. 18-22 April 2018. Huntington Beach. California. USA
4. Campolongo P. The endocannabinoid system as a potential target for memory consolidation enhancement. 17° National Congress of the Italian Neuroscience Society (SINS). 1-4 October 2017. Ischia (Italy).
5. Campolongo P. Endocannabinoids and the Regulation of Memory for Emotionally Arousing Experiences. Cannabinoid Function in the CNS. Gordon Research Conference. 20-25 August 2017. Waterville (NH) USA.
6. Campolongo P. Perinatal exposure to omega-3 fatty acid imbalance leads to enduring behavioral alterations in rats. International Behavioral Neuroscience Society (IBNS) 25th Annual Meeting. 26-30 June 2016. Budapest. Hungary
7. Campolongo P. Role of the endocannabinoid system in the modulation of memory for traumatic experiences. Colston Research Society Symposium 2015: New developments in PTSD research and treatment. 16-17 November 2015. Bristol. UK
8. Campolongo P. Role of the endocannabinoid system in the modulation of memory for emotional experiences. 37° Meeting of the Italian Society of Pharmacology. 27-30 October 2015. Naples. Italy
9. Campolongo P. Are cannabinoids potential candidates for the treatment of Post-Traumatic Stress Disorder (PTSD)? 37° Meeting of the Italian Society of Pharmacology. 27-30 October 2015. Naples. Italy
10. Campolongo P. Stress and endocannabinoid modulation of emotional memory. Mediterranean Neuroscience Society (MNS) 5th meeting. 12-15 June 2015. Santa Margherita di Pula. Italy.
11. Campolongo P. Neurobiological mechanisms mediating the impact of stress on memory: Which role for the endocannabinoid system? Lecture for the PhD school of the Ecole Polytechnique Federale de Lausanne. 10 June 2015. Lausanne. Switzerland.
12. Campolongo P. Stress and endocannabinoid modulation of aversive memory. Satellite meeting of the 9th fens forum of neuroscience. Milan, 9 July 2014.
13. Campolongo P. Stress and endocannabinoid modulation of memory for emotionally arousing experiences. 26 April 2014. Queretaro. Mexico.
14. Campolongo P. Cannabinoids and memory for emotionally arousing experiences. Symposium on stress and memory. 29-30 March 2014, Basel. Switzerland.
15. Campolongo P. and Cuomo V. Stress and endocannabinoid modulation of aversive memory: potential relevance to the development of psychiatric disorders. International symposium on International Symposium psychoneuroendocrinology: New clinical fruits from old pre-clinical seeds. 5-6 April 2014, Catania. Italy.
16. Campolongo P. Endocannabinoids in the Modulation of Memory for Stressful Experiences: New Players in an Old Game. The 5th Brain and Behavior meeting of the Haifa Forum for Brain and Behavior. 9-11 February 2014. Haifa. Israel.
17. Campolongo P. Stress and endocannabinoid modulation of emotional memory: Potential relevance for psychiatric illnesses. Topical team meeting. 3-4 February 2014, Palermo. Italy.
18. Campolongo P. Endocannabinoids and Emotional Memory Modulation: The Key Role of the Basolateral Complex of the Amygdala. 36° Congresso Nazionale della Società Italiana di Farmacologia. 23-26 October 2013. Torino, Italy.
19. Campolongo P. Stress and endocannabinoid modulation of aversive memory: Potential relevance to the development of psychiatric disorders. 36° Congresso Nazionale della Società Italiana di Farmacologia. 23-26 October 2013. Torino, Italy.
20. Campolongo P. Effects of Clinically Used Sedative/Anesthetic Drugs on Memory for Traumatic Experiences in Rats. University of Munich, Munich, Germany, 9 July 2013.
21. Campolongo P. Role of the endocannabinoid system in the modulation of memory for emotionally arousing experiences. University of Insubria. 19 Apri 2013. Busto Arsizio, Italy.
22. Campolongo P. Endocannabinoid modulation of emotional memory in rodents. Faculty at Fens-IBRO School Synaptic stress and pathogenesis of neuropsychiatric disorders. 24-30 March 2013, Bertinoro, Italy
23. Campolongo P. The endocannabinoid system and the regulation of memory for emotionally arousing experiences. 4th Conference Mediterranean Neuroscience Society. 1-4 October 2012, Istanbul, Turkey.
24. Campolongo P. Endocannabinoids: new players in emotional memory consolidation. 43° meeting European Brain and Behaviour Society (EBBS). 9-11 September 2011, Seville, Spain.
25. Campolongo P, Trezza V, Cuomo V. Endocannabinoid-glucocorticoid interaction and emotional memory in rats. 35° Congresso Nazionale della Società Italiana di Farmacologia. 14- 17 September 2011, Bologna. Italy
26. Campolongo P. Pharmacological interactions in emotional memory consolidation. The Emotional Brain Meeting. 5-6 September 2011, Rome, Italy.
27. Campolongo P. Endocannabinoids: the crucial interplay between memory and emotions. Max Planck Institute of Neuroscience. 9 June 2011, Munich, Germany.
28. Campolongo P. The role of the interaction between the endocannabinoid and glucocorticoid systems in the amygdala in the regulation of emotional memory. 40° annual meeting della Society for Neuroscience (SfN), symposium: “Stress and endocannabinoids, from synapse to behavior”). 13-17 November 2010, San Diego (USA).
29. Campolongo P. The role of endocannabinoids in the amygdala in the regulation of emotional memory. 23° annual meeting dell’European College of Neuropsychopharmacology (ECNP), TEM-symposium: "Neuropsychobiological mechanisms underlying fear memory and extinction: options for new treatment strategies". 30 August- 3 October 2010, Amsterdam, The Netherlands.
30. Campolongo P. Endocannabinoid-glucocorticoid interaction and emotional memory in rats. Symposium on Glucocorticoid-Endocannabinoid Interactions in Traumatic Memory and Posttraumatic Stress Disorder: A Translational Approach. 6-8 June, 2009, Groningen, The Netherlands.
31. Campolongo P. Glucocorticoid – Endocannabinoid Interaction and Emotional Memory in Rats. Workshop: Emotional Memory Regulation by Stress Hormones and Endocannabinoids. University of Munich, 11-12 November 2006, Munich, Germany.

ORGANIZZAZIONE SIMPOSI/CONGRESSI

Congressi e workshop:

1. Congresso Internazionale: Mediterranean Neuroscience Society (MNS). 7th Conference (June 2019). Marrakech, Marocco. Membro del comitato organizzatore.

2. International workshop. European Space Agency. Topical team on Immunity and Stress. Stress related health challenges in space: How can countermeasure research contribute to space exploration and health on Earth? March 2017. Frascati. Local organizer
3. Congresso Internazionale: Mediterranean Neuroscience Society (MNS). 5th Conference (June 2015). Santa Margherita di Pula. Italy Membro del comitato organizzatore.

4. Congresso Internazionale. The emotional brain: from neurobiology to new therapeutic opportunities. Organizzatore e presidente. Roma, Sapienza palazzo Rettorato, 5-6 settembre 2011.
5. Workshop internazionale. Primo convegno monotematico della Società Italiana di Farmacologia (SIF) 2010. International workshop on: Neurological and Psychiatric Disorders: from Neurobiology to Medicine Rome, 11/03/2010. Segreteria scientifica

Simposi:
1. Simposio. Società Italiana di Neuroscienze (SINS). XVII Congresso Nazionale (Ischia, ottobre 2017). Excess memory and excess forgetting: two tails of the same coin? Chairs: Campolongo and Macrì
2. Simposio. Mediterranean Neuroscience Society (MNS). 6th Conference (Malta, June 2017). Neurological mechanisms of the impact of stress on memory and emotionality in health and disease: Insights from animal and clinical studies. Chairs: Campolongo and Morena
3. Simposio. International Behavioral Neuroscience Society (IBNS) 25° Annual Meeting (Giugno 2016). Diet impact on brain plasticity and cognition. Chairs: Ferreira and Campolongo.
4. Simposio. Società Italiana di Farmacologia (SIF). 37° Congresso Nazionale (Napoli, Ottobre 2015). Old and new drugs in the modulation of reward and emotional behaviour Chairs: Campolongo and Ciccocioppo.
5. Simposio. Italian Society of Neuroscience (SINS). XV Conference (Ottobre 2013). An emotional perspective on the endocannabinoid system: from health to disease. Chairs: Campolongo and Trezza.
6. Simposio. Mediterranean Neuroscience Society (MNS). 4th Conference (Istanbul, Turkey, October 2012). Endocannabinoids and the control of memory and emotions. Chairs: Campolongo and Fattore.
7. Simposio. The emotional brain: from neurobiology to new therapeutic opportunities (Settembre 2011). Understanding the impact of emotional experiences on memory function: from basic mechanisms to clinical implications. Chairs: Campolongo and Schelling.
8. Simposio. International Behavioral Neuroscience Society (IBNS) 19° Annual Meeting (Giugno 2010): “Understanding the impact of emotional experiences on brain function: insights from animal and clinical studies”. Sponsored by IBRO. Chairs: Campolongo and Trezza.

ATTIVITÀ EDITORIALI E DI REVISIONE

• 2010-ad oggi Associate Editor of the journal Frontiers in Behavioral Neuroscience (Guest Editor 2010-2012)
• 2012-ad oggi Academic editor of the journal Plos One
• 2011-2012 Guest editor of the journal Reviews in the Neurosciences
• 2013-2015 Editor del libro internazionale: Endocannabinoids and modulation of emotion, memory, and motivation. Springer. 2015, I, 759. Campolongo Patrizia e Fattore Liana (Editors).
• Review di progetti internazionali (British Council in Israel; Britain-Israel Research and Academic Partnership (BIRAX); Chile National foundation; Agence Nationale de la Recherche, France).
• Review for journals: PNAS, Neuropsychopharmacology, British Journal of Pharmacology, Neuropharmacology, Neurotoxicity Research, Neurotoxicology & Teratology, Behavioural Brain Research, Behavioural Pharmacology.


PUBBLICAZIONI SCIENTIFICHE Peer reviewed
Articoli su riviste internazionali peer-reviewed:
1. Morena M, Berardi A, Colucci P, Palmery M, Trezza V, Hill MN, Campolongo P. Enhancing endocannabinoid neurotransmission augments the efficacy of extinction training ameliorates traumatic stress-induced behavioral alterations in rats. Neuropsychopharmacology. 2017 Dec 21. doi: 10.1038/npp.2017.305. [Epub ahead of print]
2. Hill MN, Campolongo P, Yehuda R, Patel S. Integrating Endocannabinoid Signaling and Cannabinoids into the Biology and Treatment of Posttraumatic Stress Disorder. Neuropsychopharmacology. 2018 Jan;43(1):80-102
3. Servadio M, Manduca A, Melancia F, Leboffe L, Schiavi S, Campolongo P, Palmery M, Ascenzi P, di Masi A, Trezza V. Impaired repair of DNA damage is associated with autistic-like traits in rats prenatally exposed to valproic acid. Eur Neuropsychopharmacol. 2018 Jan;28(1):85-96
4. Lissek T et al. Building Bridges through Science. Neuron. 2017 Nov 15;96(4):730-735.
5. Ratano P, Palmery M, Trezza V, Campolongo P. Cannabinoid Modulation of Memory Consolidation in Rats: Beyond the Role of Cannabinoid Receptor Subtype 1- Frontiers in Pharmacology. 2017. 12;8:200.
6. Morena M, Berardi A, Peloso A, Valeri D, Palmery M, Trezza V, Schelling G, Campolongo P. Effects of ketamine, dexmedetomidine and propofol anesthesia on emotional memory consolidation in rats: Consequences for the development of post-traumatic stress disorder. Behav Brain Res. 2017; 329:215-220.
7. Almenrader N, Colucci P, De Castro V, Valeri D, Palmery M, Trezza V, Campolongo P. Effects of sevoflurane and clonidine on acid base status and long-term emotional and cognitive outcomes in spontaneously breathing rat pups. PLoS One. 2017; 12(3):e0173969.
8. Esposito E, Drechsler M, Mariani P, Carducci F, Servadio M, Melancia F, Ratano P, Campolongo P, Trezza V, Cortesi R, Nastruzzi C. Lipid nanoparticles for administration of poorly water soluble neuroactive drugs. Biomed Microdevices. 2017;19(3):44.
9. Melancia F, Servadio M, Schiavi S, Campolongo P, Giusti-Paiva A, Trezza V. Testing the correlation between experimentally-induced hypothyroidism during pregnancy and autistic-like symptoms in the rat offspring. Behav Brain Res. 2017; 321:113-122.
10. Zamberletti E, Piscitelli F, De Castro V, Murru E, Gabaglio M, Colucci P, Fanali C, Prini P, Bisogno T, Maccarrone M, Campolongo P, Banni S, Rubino T, Parolaro D. Lifelong imbalanced linoleic/alpha-linolenic acid intake impairs emotional and cognitive behavior in adult rats via changes in brain endocannabinoid system. J Lipid Res. 2017; 58(2):301-316.
11. Almenrader N, Colucci P, De Castro V, Valeri D, Palmery M, Trezza V, Campolongo P. Effects of sevoflurane and clonidine on acid base status and long-term emotional and cognitive outcomes in spontaneously breathing rat pups. PLoS One. 2017 20;12(3): e0173969.
12. Manduca A, Lassalle O, Sepers M, Campolongo P, Cuomo V, Marsicano G, Kieffer B, Vanderschuren LJ, Trezza V, Manzoni OJ. Interacting Cannabinoid and Opioid Receptors in the Nucleus Accumbens Core Control Adolescent Social Play. Front Behav Neurosci. 2016; 10:211.
13. Servadio M, Melancia F, Manduca A, di Masi A, Schiavi S, Cartocci V, Pallottini V, Campolongo P, Ascenzi P, Trezza V. Targeting anandamide metabolism rescues core and associated autistic-like symptoms in rats prenatally exposed to valproic acid. Transl Psychiatry. 2016; 6(9): e902.
14. Morena M, Leitl KD, Vecchiarelli HA, Gray JM, Campolongo P, Hill MN. Emotional arousal state influences the ability of amygdalar endocannabinoid signaling to modulate anxiety. Neuropharmacology. 2016; 111:59-69.
15. Berardi A, Schelling G, Campolongo P. The endocannabinoid system and Post Traumatic Stress Disorder (PTSD): From preclinical findings to innovative therapeutic approaches in clinical settings. Pharmacol Res. 2016; 111:668-78.
16. Manduca A, Servadio M, Damsteegt R, Campolongo P, Vanderschuren LJ, Trezza V. Dopaminergic Neurotransmission in the Nucleus Accumbens Modulates Social Play Behavior in Rats. Neuropsychopharmacology. 2016;41(9):2215-23.
17. Morena M, De Castro V, Gray JM, Palmery M, Trezza V, Roozendaal B, Hill MN, Campolongo P. Training-Associated Emotional Arousal Shapes Endocannabinoid Modulation of Spatial Memory Retrieval in Rats. J Neurosci. 2015. 14;35(41):13962-74.
18. Morgese MG, Colaianna M, Mhillaj E, Zotti M, Schiavone S, D'Antonio P, Harkin A, Gigliucci V, Campolongo P, Trezza V, De Stradis A, Tucci P, Cuomo V, Trabace L. Soluble beta amyloid evokes alteration in brain norepinephrine levels: role of nitric oxide and interleukin-1. Front Neurosci. 2015. 9:428;
19. Trabace L, Tucci P, Ciuffreda L, Matteo M, Fortunato F, Campolongo P, Trezza V, Cuomo V. "Natural" relief of pregnancy-related symptoms and neonatal outcomes: above all do no harm. J Ethnopharmacol. 2015 (15)30113-6.
20. Manduca A, Morena M, Campolongo P, Servadio M, Palmery M, Trabace L, Hill MN, Vanderschuren LJ, Cuomo V, Trezza V. Distinct roles of the endocannabinoids anandamide and 2-arachidonoylglycerol in social behavior and emotionality at different developmental ages in rats. Eur Neuropsychopharmacol. 2015 25(8):1362-74.
21. Atsak P, Hauer D, Campolongo P, Schelling G, Fornari RV, Roozendaal B. Endocannabinoid signaling within the basolateral amygdala integrates multiple stress hormone effects on memory consolidation. Neuropsychopharmacology. 2015. 40(6):1485-94.
22. Esposito E, Ravani L, Drechsler M, Mariani P, Contado C, Ruokolainen J, Ratano P, Campolongo P, Trezza V, Nastruzzi C, Cortesi R. Cannabinoid antagonist in nanostructured lipid carriers (NLCs): Design, characterization and in vivo study. Materials Science and Engineering C, 2015 48:328-336.
23. Morena M, Roozendaal B, Trezza V, Ratano P, Peloso A, Hauer D, Atsak P, Trabace L, Cuomo V, McGaugh JL, Schelling G, Campolongo P. Endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training. PNAS. 2014. 111(51):18333-8.
24. Berardi A, Trezza V, Palmery M, Trabace L, Cuomo V, Campolongo P. An updated animal model capturing both the cognitive and emotional features of post-traumatic stress disorder (PTSD). Frontiers in behavioral neuroscience. 2014, 8:142.
25. Morena M and Campolongo P. The endocannabinoid system: An emotional buffer in the modulation of memory function. Neurobiology of learning and memory. 2014, 112:30-43. Invited review.
26. Tucci P, Mhillaj E, Morgese MG, Colaianna M, Zotti M, Schiavone S, Cicerale M, Trezza V, Campolongo P, Cuomo V, Trabace L. Memantine prevents memory consolidation failure induced by soluble beta amyloid in rats. Frontiers in behavioral neuroscience. 2014 8:332.
27. Scuderi C, Stecca C, Valenza M, Ratano P, Bronzuoli M, Bartoli S, Steardo L jr, Pompili E, Fumagalli L, Campolongo P, Steardo L. Palmitoylethanolamide controls reactive gliosis and exerts neuroprotective functions in a rat model of Alzheimer's disease. Cell Death & Disease. 2014, Sep 11;5:e1419. doi: 10.1038/cddis.2014.37.
28. Manduca A, Servadio M, Campolongo P, Palmery M, Trabace L, Vanderschuren LJ, Cuomo V, Trezza V. Strain- and context-dependent effects of the anandamide hydrolysis inhibitor URB597 on social behavior in rats. European Neuropsychopharmacology 2014, 24(8):1337-48.
29. Manduca A, Campolongo P, Palmery M, Vanderschuren LJMJ, Cuomo V, Trezza V. Social play behavior, ultrasonic vocalizations and their modulation by morphine and amphetamine in Wistar and Sprague-Dawley rats. Psychopharmacology. 2014, 231(8):1661-73.
30. Thieme U, Schelling G, Hauer D, Greif R, Dame T, Laubender RP, Bernhard W, Thieme D, CampolongoP, Theilerb L. Quantification of anandamide and 2-arachidonoylglycerol plasma levels to examine potential influences of tetrahydrocannabinol application on the endocannabinoid system in humans. Drug testing and analysis. 2014, 6(1-2):17-23.
31. Hauer D, Kaufmann I, Strewe C, Briegel I, Campolongo P, Schelling G. The Role of Glucocorticoids, Catecholamines and Endocannabinoids in the Development of Traumatic Memories and Posttraumatic Stress Symptoms in Survivors of Critical Illness. Neurobiology of learning and memory 2014. 112:68-74.
32. Campolongo P, Ratano P, Ciotti MT, Florenzano F, Lucia Nori S, Marolda R, Palmery M, Rinaldi AM, Zona C, Possenti R, Calissano P, Severini C. Systemic administration of Substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels. Plos One. 2013, 8(11):e78036.
33. Trezza V and Campolongo P. The endocannabinoid system as a possible target to treat both the cognitive and emotional features of post-traumatic stress disorder. Frontiers in behavioral neuroscience. 2013, 6:73.
34. Campolongo P, Morena M, Scaccianoce S, Trezza V, Chiarotti F, Schelling G, Cuomo V, Roozendaal B. Novelty-induced emotional arousal modulates cannabinoid effects on recognition memory and adrenocortical activity. Neuropsychopharmacology. 2013, 38(7):1276-86.
35. Hauer D, Schelling G, Gola H, Campolongo P, Morath J, Roozendaal B, Hamuni G, Karabatsiakis A, Atsak P, Vogeser M, Kolassa I. Plasma Concentrations of Endocannabinoids and Related Primary Fatty Acid Amides in Patients with Post-Traumatic Stress Disorder. Plos One. 2013, 7;8(5):e62741.
36. Campolongo P, Tomaz C, Gasbarri A. The emotional brain and its relation to psychopathology. Reviews in the Neurosciences. 2012, 23(5-6):445-7;
37. Campolongo P, Trezza V. The endocannabinoid system: a key modulator of emotions and cognition. Frontiers in Behavioral Neuroscience. 2012, 6:73.
38. Berardi A, Trezza V, Campolongo P. Modeling specific phobias and post-traumatic stress disorder in rodents: the challenge to convey both cognitive and emotional features. Reviews in the Neurosciences. 2012, 23(5-6):645-57. Invited review.
39. Trezza V, Damsteegt R, Manduca A, Petrosino S, Van Kerkhof LWM, Pasterkamp RJ, Zhou Y, Campolongo P, Cuomo V, Di Marzo V, Vanderschuren LJMJ. Endocannabinoids in amygdala and nucleus accumbens mediate social play reward in adolescent rats. The Journal of Neuroscience. 2012, 32(43):14899-908.
40. Manduca A, Campolongo P, Trezza V. Cannabinoid modulation of mother-infant interaction: is it just about milk? Reviews in the Neurosciences. 2012;23(5-6):707-22.
41. Hauer D, Weis F, Campolongo P, Schopp M, Beiras-Fernandez A, Strewe C, Giehl M, Toth R, Kilger E, Schelling G. Glucocorticoid-endocannabinoid interaction in cardiac surgical patients: relationship to early cognitive dysfunction and late depression. Reviews in the Neurosciences. 2012, 23(5-6):681-90.
42. Atsak P, Hauer D, Campolongo P, Schelling G, McGaugh JL, Roozendaal B. Glucocorticoids interact with the hippocampal endocannabinoid system in impairing retrieval of contextual fear memory. PNAS. 2012, 109(9):3504-9.
43. Campolongo P, Ratano P, Manduca A, Scattoni ML, Palmery M, Trezza V, Cuomo V. The endocannabinoid transport inhibitor AM404 differentially modulates recognition memory in rats depending on environmental aversiveness. Frontiers in Behavioral Neuroscience. 2012; 6:11.
44. Atsak P, Roozendaal B, Campolongo P. Role of the endocannabinoid system in regulating glucocorticoid effects on memory for emotional experiences. Neuroscience. 2011, 204:104-16. Invited review
45. Trezza V, Campolongo P, Manduca A, Morena M, Palmery M, Vanderschuren LJMJ, Cuomo V. Altering endocannabinoid neurotransmission at critical developmental ages: impact on rodent emotionality and cognitive performance. Frontiers in Behavioral Neuroscience. 2012, 6:2-20.
46. Trezza V, Campolongo P, Vanderschuren LJMJ. Evaluating the rewarding nature of social interactions in laboratory animals. Developmental Cognitive Neuroscience. 2011, 1(4):444-58. IF= 3.705
47. Trapani L, Melli L, Segatto M, Trezza V, Campolongo P, Jozwiak A, Sweiezewska E, Pupillo LP, Moreno S, Fanelli F, Linari M, Pallottini V. Effects of myosin heavy chain (MHC) plasticity induced by HMGCoA-reductase inhibition on skeletal muscle functions. Faseb J. 2011, 25(11):4037-47.
48. Hauer D, Ratano P, Morena M, Briegel I, Scaccianoce S; Palmery M, Cuomo V, Roozendaal B, Schelling G, Campolongo P. Propofol enhances long-term memory formation via an interaction with the endocannabinoid system. Anesthesiology. 2011,114(6):1380-8.
49. Hill M, Patel S, Campolongo P, Tasker J, Wotjak C, Bains J. Functional interactions between stress and the endocannabinoid system: From synaptic signalling to behavioral ouput. The Journal of Neuroscience. 2010, 30(45):14980-6.
50. Campolongo P, Trezza V, Ratano P, Palmery M, Cuomo V. Developmental consequences of perinatal cannabis exposure: behavioral and neuroendocrine effects in adult rodents. Psychopharmacology (Berl). 2011, 214(1):5-15. Invited review.
51. Campolongo P, Roozendaal B, Trezza V, Hauer D, Schelling G, McGaugh JL, Cuomo V. Endocannabinoids in the rat basolateral amygdala enhance memory consolidation: involvement of the glucocorticoid system. PNAS 2009, 106(12):4888-93.
52. Trezza V, Campolongo P. Toward understanding the neurobiology of social attachment: role of estrogen receptors in the medial amygdala. The Journal of Neuroscience. 2009; 29(1):1-2.
53. Campolongo P, Roozendaal B, Trezza V, Cuomo V, Astarita G, Fu J, McGaugh JL, Piomelli D. Fat-induced satiety factor OEA enhances memory consolidation. PNAS 2009, 106(19):8027-31.
54. Campolongo P, Trezza V, Palmery M, Trabace L, Cuomo V. Developmental exposure to cannabinoids causes subtle and enduring neurofunctional alterations. International Reviews of Neurobiology 2009, 85:117-33. Invited review
55. Kaufmann I, Hauer D, Huge V, Vogeser M, Campolongo P, Chouker A, Thiel M, Schelling G. Enhanced anandamide plasma levels in patients with CRPS following traumatic injury: a preliminary report. Eur Surg Res. 2009 ;43(4):325-329.
56. Kaufmann I, Schelling G, Eisner C, Richter HP, Krauseneck T, Vogeser M, Hauer D, Campolongo P, Chouker A, Beyer A, Thiel M. Anandamide and neutrophil function in patients with fibromyalgia. Psychoneuroendocrinology. 2008, 33(5):676-685.
57. Trezza V*, Campolongo P*, Cassano T, Macheda T, Dipasquale P, Carratù MR, Gaetani S, Cuomo V. Effects of perinatal exposure to delta-9-tetrahydrocannabinol on the emotional reactivity of the offspring: a longitudinal behavioral study in Wistar rats. Psychopharmacology 2008; 198(4): 529-37; equal contribution.
58. Schwartz GJ; Fu J; Astarita G; Li X; Gaetani S; Campolongo P; Cuomo V; Piomelli D. The lipid messenger OEA links dietary fat intake to satiety. Cell Met. 2008; 8(4):281-8.
59. Campolongo P, Trezza V, Cassano T, Gaetani S, Morgese MG, Ubaldi M, Soverchia L, Antonelli T, Ferraro L, Massi M, Ciccocioppo R, Cuomo V. Perinatal exposure to delta-9-tetrahydrocannabinol causes enduring cognitive deficits associated with alteration of cortical gene expression and neurotransmission in rats. Addiction Biology. 2007; 12(3-4):485-95.
60. Barbaccia ML, Scaccianoce S, Del Bianco P, Campolongo P, Trezza V, Tattoli M, Cuomo V, Steardo L. Cognitive impairment and increased brain neurosteroids in adult rats perinatally exposed to low millimolar blood alcohol concentrations. Psychoneuroendocrinology, 2007; 32(8-10): 931-42.
61. Economidou D, Mattioli L, Ubaldi M, Lourdusamy A, Soverchia L, Hardiman G, Campolongo P, Cuomo V, Ciccocioppo R. Role of cannabinoidergic mechanisms in ethanol self-administration and ethanol-seeking in adult rats following perinatal exposure to delta-9-tetrahydrocannabinol. Toxicology Applied Pharmacology 2007; 223(1): 73-85.
62. La Rana G, Russo R, Campolongo P, Bortolato M, Mangieri RA, Cuomo V, Iacono A, Mattace Raso G, Meli R, Piomelli D, Calignano A. Modulation of neuropathic and inflammatory pain by the endocannabinoid transport inhibitor AM404. Journal Pharmacology Experimental Therapeutics. 2006, 317(3):1365-71.
63. Bortolato M*, Campolongo P*, Mangieri RA, Scattoni ML, Frau R, Trezza V, La Rana G, Russo R, Calignano A, Gessa GL, Cuomo V, Piomelli D. Anxiolytic-Like Properties of the Anandamide Transport Inhibitor AM404. Neuropsychopharmacology. 2006, 31(12):2652-9; * equal contribution.
64. Gobbi G, Bambico FR, Mangieri R, Bortolato M, Campolongo P, Solinas M, Cassano T, Morgese MG, Debonnel G, Duranti A, Tontini A, Tarzia G, Mor M, Trezza V, Goldberg SR, Cuomo V, Piomelli D. Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. PNAS. 2005; 20;102(51):18620-5.
65. Branchi I, Campolongo P, Alleva E. Scopolamine effects on ultrasonic vocalization emission and behavior in the neonatal mouse. Behav Brain Res. 2004; 151: 9-16.
66. Peluso I, Serafini M, Campolongo P, Palmery M. Effect on rat arterial blood pressure of chemically generated peroxyl radicals and protection by antioxidants. J Nutr Biochem. 2004; 15(6): 323-7.
67. Spano D, Branchi I, Rosica A, Pirro MT, Riccio A, Mithbaokar P, Affuso A, Arra C, Campolongo P, Terracciano C, Macchia V, Bernal J, Alleva E, Di Lauro R. Rhes is involved in striatal function. Mol Cell Biol. 2004; 24(13): 5788-96.
68. Peluso I, Campolongo P, Romanelli L, Valeri P, Palmery M. Intestinal motility disorder induced by free radicals: a new model mimicking oxidative stress in gut. Pharmacol Res. 2002 Dec;46(6):533-8.

Libri internazionali (editor)
Campolongo, P & Fattore L. Cannabinoid modulation of emotion, memory, and motivation. Springer New York. 2015. 467 pag. DOI: 10.1007/978-1-4939-2294-9

Libri internazionali (capitoli):

1. Morena M and Campolongo P. Endocannabinoid modulation of memory for emotionally arousing experiences. In: Campolongo and Fattore (eds.) Endocannabinoids and modulation of emotion, memory, and motivation. Springer. 2015, pp. 3-22.
2. Atsak P, Roozendaal B, Campolongo P. Role of Endocannabinoids in Regulating Glucocorticoid Effects on Memory for Emotionally Arousing Experiences. In: Popoli, Diamond and Sanacora (eds.) Synaptic Stress and Pathogenesis of Neuropsychiatric Disorders. Springer. 2014, pp 77-98
3. Campolongo P and Roozendaal B. Stress and glucocorticoid effects on memory. In: Conrad CD (ed). Handbook of Stress: Neuropsychological Effects on the Brain. Malden: Wiley-Blackwell. 2013. pp 179-200.