11573/1692856 - 2024 -
SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma Lospinoso Severini, Ludovica; Loricchio, Elena; Navacci, Shirin; Basili, Irene; Alfonsi, Romina; Bernardi, Flavia; Moretti, Marta; Conenna, Marilisa; Cucinotta, Antonino; Coni, Sonia; Petroni, Marialaura; De Smaele, Enrico; Giannini, Giuseppe; Maroder, Marella; Canettieri, Gianluca; Mastronuzzi, Angela; Guardavaccaro, Daniele; Ayrault, Olivier; Infante, Paola; Bufalieri, Francesca; Di Marcotullio, Lucia - 01a Articolo in rivista
rivista: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. - - issn: 1350-9047 - wos: WOS:001119029000002 (3) - scopus: 2-s2.0-85178929821 (3)
11573/1711740 - 2024 -
Natural compound as anticancer agent: in vitro experimental evidence in Intrahepatic Cholangiocarcinoma Paradiso, S.; Carpino, G.; Botta, B.; Quaglio, D.; Di Meo, C.; Infante, P.; Di Marcotullio, L.; Gaudio, E.; Alvaro, D.; Cardinale, V. - 04f Poster
congresso: The 2024 Annual Congress of the European Association for Cancer Research: Innovative Cancer Science (Rotterdam - Netherlands)
libro: Molecular Oncology - ()
11573/1721054 - 2024 -
First proof-of-concept study on targeting Hedgehog pathway in intrahepatic cholangiocarcinoma histological subtypes Paradiso, S.; Carpino, G.; Di Meo, C.; Quaglio, D.; Infante, P.; Di Marcotullio, L.; De Luca, T.; Franchitto, M.; Botta, B.; Gaudio, E.; Alvaro, D.; Cardinale, V. - 04f Poster
congresso: 64th annual Meeting of the Italian Cancer Society: "Science-driven approaches to achieve early diagnosis of cancer and to overcome therapy” (Milan, Italy)
libro: 64nd Annual Meeting of the Italian Cancer Society: "Science-driven approaches to achieve early diagnosis of cancer and to overcome therapy resistance" - Abstract Book - ()
11573/1722499 - 2024 -
Dissecting the hindrance of Hedgehog pathway in Intrahepatic Cholangiocarcinoma: a step towards targeted therapy Paradiso, S.; Carpino, G.; Infante, P.; Di Marcotullio, L.; Quaglio, D.; Di Meo, C.; Franchitto, M.; De Luca, T.; Botta, B.; Gaudio, E.; Alvaro, D.; Cardinale, V. - 04d Abstract in atti di convegno
rivista: UNITED EUROPEAN GASTROENTEROLOGY JOURNAL ([London] : SAGE Publications) pp. 61-61 - issn: 2050-6414 - wos: (0) - scopus: (0)
congresso: 32nd United European Gastroenterology Week 2024 (Vienna, Austria)
libro: UNITED EUROPEAN GASTROENTEROLOGY JOURNAL - ()
11573/1705007 - 2024 -
Imparing proliferation, survival and invasiveness of Intrahepatic Cholangiocarcinoma through a novel natural Hedgehog pathway inhibitor Paradiso, S.; Carpino, G.; Quaglio, D.; Ghirga, F.; Di Meo, C.; Paoletti, L.; De Luca, T.; Franchitto, M.; Di Marcotullio, L.; Infante, P.; Gaudio, E.; Alvaro, D.; Cardinale, V. - 04f Poster
congresso: Liver Cancer Summit 2024 (Rotterdam - Netherlands)
libro: Liver Cancer Summit 2024 - Abstract Book - ()
11573/1706413 - 2024 -
Targeting Hedgehog signaling pathway by a natural compound: a promising approach for anti-cancer therapeutic development in Intrahepatic Cholangiocarcinoma Paradiso, S.; Carpino, G.; Quaglio, D.; Ghirga, F.; Di Meo, C.; Paoletti, L.; De Luca, T.; Franchitto, M.; Di Marcotullio, L.; Infante, P.; Gaudio, E.; Alvaro, D.; Cardinale, V. - 04f Poster
congresso: 56th Annual Meeting of the Italian Association for the Study of the Liver (Rome; Italy)
libro: Digestive and Liver Disease - ()
11573/1707903 - 2024 -
Potential of a natural compound as hedgehog pathway inhibitor for the treatment of intrahepatic cholangiocarcinoma Paradiso, S.; Carpino, G.; Quaglio, D.; Ghirga, F.; Di Meo, C.; Paoletti, L.; De Luca, T.; Franchitto, M.; Di Marcotullio, L.; Infante, P.; Gaudio, E.; Alvaro, D.; Cardinale, V. - 04d Abstract in atti di convegno
rivista: DIGESTIVE AND LIVER DISEASE (-Roma: Editrice Gastroenterologica Italiana; Milano: Elsevier
-Roma: Editrice Gastroenterologica Italiana.
-Ospedaletto Pisa: Pacini) pp. 156-156 - issn: 1590-8658 - wos: (0) - scopus: (0)
congresso: 30th National Congress of Digestive Disease Italian Federation of Societies of Digestive Diseases – FISMAD (Rome; Italy)
libro: 30th National Congress of Digestive Disease Italian Federation of Societies of Digestive Diseases – FISMAD - ()
11573/1693758 - 2023 -
GLI1-selective inhibitor, Glabrescione B, impairs proliferation in intrahepatic cholangiocarcinoma Paradiso, S.; Carpino, G.; Quaglio, D.; Ghirga, F.; Di Meo, C.; Paoletti, L.; De Luca, T.; Cremisini, F.; Franchitto, M.; Di Marcotullio, L.; Infante, P.; Gaudio, E.; Alvaro, D.; Cardinale, V. - 04f Poster
rivista: UNITED EUROPEAN GASTROENTEROLOGY JOURNAL ([London] : SAGE Publications) pp. 1335-1336 - issn: 2050-6414 - wos: (0) - scopus: (0)
congresso: 31st United European Gastroenterology Week 2023 (Copenhagen, Denmark)
libro: United European Gastroenterology JournalVolume 11: 31st United European Gastroenterology Week 2023 - ()
11573/1687539 - 2023 -
Exploring the potential of anthraquinone-based hybrids for identifying a novel generation of antagonists for the Smoothened receptor in HH-dependent tumour Quaglio, Deborah; Infante, Paola; Cammarone, Silvia; Lamelza, Lara; Conenna, Marilisa; Ghirga, Francesca; Adabbo, Gennaro; Pisano, Luca; Di Marcotullio, Lucia; Botta, Bruno; Mori, Mattia - 01a Articolo in rivista
rivista: CHEMISTRY (Weinheim: Wiley-VCH-Verl..) pp. - - issn: 1521-3765 - wos: WOS:001071179800001 (1) - scopus: 2-s2.0-85172686997 (0)
11573/1671630 - 2022 -
Combined mitoxantrone and anti-TGFβ treatment with PD-1 blockade enhances antitumor immunity by remodelling the tumor immune landscape in neuroblastoma # 1, Valeria Lucarini; # 1 2, Ombretta Melaiu; 1, Silvia D'amico; 3, Fabio Pastorino; Tempora, Patrizia; 4, Marco Scarsella; 5, Marco Pezzullo; 6, Adele De Ninno; 7, Valentina D'oria; 8, Michele Cilli; 8, Laura Emionite; Infante, Paola; 9, Lucia Di Marcotullio; 1, Maria Antonietta De Ioris; 2, Giovanni Barillari; Alaggio, Rita; 6, Luca Businaro; 3, Mirco Ponzoni; 1 11, Franco Locatelli; Fruci 12, Doriana - 01a Articolo in rivista
rivista: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. - - issn: 1756-9966 - wos: WOS:000885027500001 (11) - scopus: 2-s2.0-85142102667 (11)
11573/1631459 - 2022 -
Proteolysis-Targeting Chimera (PROTAC): Is the Technology Looking at the Treatment of Brain Tumors? Lospinoso Severini, L.; Bufalieri, F.; Infante, P.; Di Marcotullio, L. - 01g Articolo di rassegna (Review)
rivista: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. 854352- - issn: 2296-634X - wos: WOS:000770668600001 (7) - scopus: 2-s2.0-85125677503 (9)
11573/1613663 - 2021 -
SMA-miRs (MiR-181a- 5p, -324-5p, and -451a) are overexpressed in spinal muscular atrophy skeletal muscle and serum samples Abiusi, E.; Infante, P.; Cagnoli, C.; Severini Lospinoso, L.; Pane, M.; Coratti, G.; Pera, M. C.; D'amico, A.; Diano, F.; Novelli, A.; Spartano, S.; Fiori, S.; Baranello, G.; Moroni, I.; Mora, M.; Pasanisi, M. B.; Pocino, K.; Le Pera, L.; D'amico, D.; Travaglini, L.; Ria, F.; Bruno, C.; Locatelli, D.; Bertini, E. S.; Morandi, L. O.; Mercuri, E.; Di Marcotullio, L.; Tiziano, F. D. - 01a Articolo in rivista
rivista: ELIFE (Cambridge: eLife Sciences Publications) pp. - - issn: 2050-084X - wos: WOS:000703785000001 (14) - scopus: 2-s2.0-85116897057 (15)
11573/1560455 - 2021 -
Design and synthesis of new withaferin A inspired hedgehog pathway inhibitors Bonandi, E.; Mori, M.; Infante, P.; Basili, I.; Di Marcotullio, L.; Calcaterra, A.; Catti, F.; Botta, B.; Passarella, D. - 01a Articolo in rivista
rivista: CHEMISTRY-A EUROPEAN JOURNAL (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 8350-8357 - issn: 0947-6539 - wos: WOS:000646619600001 (5) - scopus: 2-s2.0-85105325845 (6)
11573/1560767 - 2021 -
Harnessing the activation of RIG-I like receptors to inhibit glioblastoma tumorigenesis Bufalieri, Francesca; Basili, Irene; Di Marcotullio, Lucia; Infante, Paola - 01g Articolo di rassegna (Review)
rivista: FRONTIERS IN MOLECULAR NEUROSCIENCE (Lausanne: Frontiers Research Foundation, 2008-) pp. - - issn: 1662-5099 - wos: WOS:000675519000001 (6) - scopus: 2-s2.0-85111069951 (6)
11573/1613665 - 2021 -
Drug delivery systems for hedgehog inhibitors in the treatment of SHH-medulloblastoma Caimano, M.; Lospinoso Severini, L.; Loricchio, E.; Infante, P.; Di Marcotullio, L. - 01g Articolo di rassegna (Review)
rivista: FRONTIERS IN CHEMISTRY (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-2646 - wos: WOS:000663813400001 (13) - scopus: 2-s2.0-85108348605 (13)
11573/1569898 - 2021 -
A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors Di Giulio, Stefano; Colicchia, Valeria; Pastorino, Fabio; Pedretti, Flaminia; Fabretti, Francesca; Nicolis Di Robilant, Vittoria; Ramponi, Valentina; Scafetta, Giorgia; Moretti, Marta; Licursi, Valerio; Belardinilli, Francesca; Peruzzi, Giovanna; Infante, Paola; Goffredo, Bianca Maria; Coppa, Anna; Canettieri, Gianluca; Bartolazzi, Armando; Ponzoni, Mirco; Giannini, Giuseppe; Petroni, Marialaura - 01a Articolo in rivista
rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. - - issn: 0950-9232 - wos: WOS:000694774500002 (18) - scopus: 2-s2.0-85118235580 (20)
11573/1472828 - 2021 -
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma Infante, P.; Malfanti, A.; Quaglio, D.; Balducci, S.; De Martin, S.; Bufalieri, F.; Mastrotto, F.; Basili, I.; Garofalo, M.; Lospinoso Severini, L.; Mori, M.; Manni, I.; Moretti, M.; Nicoletti, C.; Piaggio, G.; Caliceti, P.; Botta, B.; Ghirga, F.; Salmaso, S.; Di Marcotullio, L. - 01a Articolo in rivista
rivista: CANCER LETTERS (Elsevier Science Ireland Limited:PO Box 85, Limerick Ireland:011 353 61 709600, 011 353 61 61944, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 353 61 709114) pp. 220-231 - issn: 0304-3835 - wos: WOS:000604424500023 (22) - scopus: 2-s2.0-85097086576 (26)
11573/1471927 - 2021 -
Nutlin-3a enhances natural killer cell-mediated killing of neuroblastoma by restoring p53-dependent expression of ligands for NKG2D and DNAM-1 receptors Veneziani, Irene; Infante, Paola; Ferretti, Elisa; Melaiu, Ombretta; Battistelli, Cecilia; Lucarini, Valeria; Compagnone, Mirco; Nicoletti, Carmine; Castellano, Aurora; Petrini, Stefania; Ognibene, Marzia; Pezzolo, Annalisa; Di Marcotullio, Lucia; Bei, Roberto; Moretta, Lorenzo; Pistoia, Vito; Fruci, Doriana; Barnaba, Vincenzo; Locatelli, Franco; Cifaldi, Loredana - 01a Articolo in rivista
rivista: CANCER IMMUNOLOGY RESEARCH (American Association for Cancer Research, Inc. (AACR), 615 Chestnut St., 17th Floor Philadelphia, PA 19106-4404; Phone: (215) 440-9300 or Toll Free: (866) 423-3965; Fax: (215) 446-7289; E-mail: cancerimmunolres@aacr.org.) pp. 170-183 - issn: 2326-6066 - wos: WOS:000618209900006 (30) - scopus: 2-s2.0-85100390757 (31)
11573/1399216 - 2020 -
Clinical Multigene Panel Sequencing Identifies Distinct Mutational Association Patterns in Metastatic Colorectal Cancer Belardinilli, Francesca; Capalbo, Carlo; Malapelle, Umberto; Pisapia, Pasquale; Raimondo, Domenico; Milanetti, Edoardo; Mahdavian, Yasaman; Liccardi, Carlotta; Paci, Paola; Sibilio, Pasquale; Pepe, Francesco; Bonfiglio, Caterina; Mezi, Silvia; Magri, Valentina; Coppa, Anna; Nicolussi, Arianna; Gradilone, Angela; Petroni, Marialaura; Di Giulio, Stefano; Fabretti, Francesca; Infante, Paola; Coni, Sonia; Canettieri, Gianluca; Troncone, Giancarlo; Giannini, Giuseppe - 01a Articolo in rivista
rivista: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. - - issn: 2234-943X - wos: WOS:000536940500001 (11) - scopus: 2-s2.0-85085205712 (12)
11573/1384478 - 2020 -
The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i Bufalieri, F.; Caimano, M.; Severini, L. L.; Basili, I.; Paglia, F.; Sampirisi, L.; Loricchio, E.; Petroni, M.; Canettieri, G.; Santoro, A.; D'angelo, L.; Infante, P.; Di Marcotullio, L. - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. 321- - issn: 2072-6694 - wos: WOS:000522477300067 (42) - scopus: 2-s2.0-85079068523 (40)
11573/1560331 - 2020 -
Dubs activating the hedgehog signaling pathway: a promising therapeutic target in cancer Bufalieri, F.; Lospinoso Severini, L.; Caimano, M.; Infante, P.; Di Marcotullio, L. - 01g Articolo di rassegna (Review)
rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000549233900001 (11) - scopus: 2-s2.0-85086322190 (17)
11573/1471575 - 2020 -
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation Coni, S.; Serrao, S. M.; Yurtsever, Z. N.; Di Magno, L.; Bordone, R.; Bertani, C.; Licursi, V.; Ianniello, Z.; Infante, P.; Moretti, M.; Petroni, M.; Guerrieri, F.; Fatica, A.; Macone, A.; De Smaele, E.; Di Marcotullio, L.; Giannini, G.; Maroder, M.; Agostinelli, E.; Canettieri, G. - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000597627300001 (45) - scopus: 2-s2.0-85097416564 (47)
11573/1364966 - 2020 -
Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module Di Magno, L.; Manni, S.; Di Pastena, F.; Coni, S.; Macone, A.; Cairoli, S.; Sambucci, M.; Infante, P.; Moretti, M.; Petroni, M.; Nicoletti, C.; Capalbo, C.; De Smaele, E.; Di Marcotullio, L.; Giannini, G.; Battistini, L.; Goffredo, B. M.; Iorio, E.; Agostinelli, E.; Maroder, M.; Canettieri, G. - 01a Articolo in rivista
rivista: CELL REPORTS (Elsevier B.V.
Cambridge MA: Cell Press) pp. 1735-1752 - issn: 2211-1247 - wos: WOS:000513920800008 (41) - scopus: 2-s2.0-85079335561 (41)
11573/1560340 - 2020 -
The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma Lospinoso Severini, L.; Ghirga, F.; Bufalieri, F.; Quaglio, D.; Infante, P.; Di Marcotullio, L. - 01g Articolo di rassegna (Review)
rivista: EXPERT OPINION ON THERAPEUTIC TARGETS (--London United Kingdom:Informa Healthcare
-London : Ashley, 2002-.) pp. 1159-1181 - issn: 1472-8222 - wos: WOS:000573407600001 (36) - scopus: 2-s2.0-85091689870 (37)
11573/1384485 - 2020 -
Hedgehog signaling pathway inhibitors: an updated patent review (2015–present) Quaglio, D.; Infante, P.; Di Marcotullio, L.; Botta, B.; Mori, M. - 01g Articolo di rassegna (Review)
rivista: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare
-London, United Kingdom: Ashley Publications Limited) pp. 235-250 - issn: 1354-3776 - wos: WOS:000514863500001 (38) - scopus: 2-s2.0-85079776320 (40)
11573/1559760 - 2020 -
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold Romeo, Isabella; Lospinoso Severini, Ludovica; Quaglio, Deborah; Basili, Irene; Ghirga, Francesca; Bufalieri, Francesca; Caimano, Miriam; Balducci, Silvia; Moretti, Marta; Loricchio, Elena; Maroder, Marella; Botta, Bruno; Mori, Mattia; Infante, Paola; Di Marcotullio, Lucia - 04f Poster
congresso: STRATAGEM COST CA17104: New diagnostic and therapeutic tools against multidrug resistant tumors (virtual meeting - online mode)
libro: Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold - ()
11573/1559014 - 2020 -
mPEG5kDa-cholane/Glabrescione B delivery system as promising tool for the treatment of Hh-dependent tumors Vergine, Valeria; Infante, Paola; Malfanti, Alessio; Quaglio, Deborah; Balducci, Silvia; De Martin, Sara; Bufalieri, Francesca; Mastrotto, Francesca; Basili, Irene; Garofalo, Mariangela; Lospinoso Severini, Ludovica; Mori, Mattia; Manni, Isabella; Moretti, Marta; Nicoletti, Carmine; Piaggio, Giulia; Caliceti, Paolo; Botta, Bruno; Ghirga, Francesca; Salmaso, Stefano; Di Marcotullio, Lucia - 04f Poster
congresso: Stratagem cost WG2 on Synthesis and nanodelivery strategies for new therapeutic tools against Multidrug Resistant Tumours (online)
libro: Cost Action 17104(Stratagem) - ()
11573/1304369 - 2019 -
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP Bufalieri, F.; Infante, P.; Bernardi, F.; Caimano, M.; Romania, P.; Moretti, M.; Lospinoso Severini, L.; Talbot, J.; Melaiu, O.; Tanori, M.; Di Magno, L.; Bellavia, D.; Capalbo, C.; Puget, S.; De Smaele, E.; Canettieri, G.; Guardavaccaro, D.; Busino, L.; Peschiaroli, Angelo; Pazzaglia, S.; Giannini, G.; Melino, G.; Locatelli, F.; Gulino, A.; Ayrault, O.; Fruci, D.; Di Marcotullio, L. - 01a Articolo in rivista
rivista: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. 1-15 - issn: 2041-1723 - wos: WOS:000476877400003 (40) - scopus: 2-s2.0-85069646549 (41)
11573/1224164 - 2019 -
A simplified genomic profiling approach predicts outcome in metastatic colorectal cancer Capalbo, Carlo; Belardinilli, Francesca; Raimondo, Domenico; Milanetti, Edoardo; Malapelle, Umberto; Pisapia, Pasquale; Magri, Valentina; Prete, Alessandra; Pecorari, Silvia; Colella, Mariarosaria; Coppa, Anna; Bonfiglio, Caterina; Nicolussi, Arianna; Valentini, Virginia; Tessitore, Alessandra; Cardinali, Beatrice; Petroni, Marialaura; Infante, Paola; Santoni, Matteo; Filetti, Marco; Colicchia, Valeria; Paci, Paola; Mezi, Silvia; Longo, Flavia; Cortesi, Enrico; Marchetti, Paolo; Troncone, Giancarlo; Bellavia, Diana; Canettieri, Gianluca; Giannini, Giuseppe - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000460747200021 (9) - scopus: 2-s2.0-85061991505 (9)
11573/1347787 - 2019 -
Discovery, characterization and potential roles of a novel NF-YAx splice variant in human neuroblastoma Cappabianca, L.; Farina, A. R.; Di Marcotullio, L.; Infante, P.; De Simone, D.; Sebastiano, M.; Mackay, A. R. - 01a Articolo in rivista
rivista: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. 482- - issn: 1756-9966 - wos: WOS:000515095500001 (12) - scopus: 2-s2.0-85076223386 (14)
11573/1347816 - 2019 -
1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma D'alessandro, G.; Quaglio, D.; Monaco, L.; Lauro, C.; Ghirga, F.; Ingallina, C.; De Martino, M.; Fucile, S.; Porzia, A.; Di Castro, M. A.; Bellato, F.; Mastrotto, F.; Mori, M.; Infante, P.; Turano, P.; Salmaso, S.; Caliceti, P.; Di Marcotullio, L.; Botta, B.; Ghini, V.; Limatola, C.; Monaco, Lucia - 01a Articolo in rivista
rivista: CELL COMMUNICATION AND SIGNALING (BioMed Central, London) pp. 108- - issn: 1478-811X - wos: WOS:000485121800001 (30) - scopus: 2-s2.0-85071619755 (31)
11573/1318627 - 2019 -
Targeting hedgehog signalling through the ubiquitylation process: the multiple roles of the HECT-E3 ligase itch Infante, Paola; Lospinoso Severini, Ludovica; Bernardi, Flavia; Bufalieri, Francesca; Di Marcotullio, Lucia - 01g Articolo di rassegna (Review)
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 98- - issn: 2073-4409 - wos: WOS:000460896000020 (16) - scopus: 2-s2.0-85073565486 (20)
11573/1321077 - 2019 -
A Smo/Gli multitarget hedgehog pathway inhibitor impairs tumor growth Lospinoso Severini, Ludovica; Quaglio, Deborah; Basili, Irene; Ghirga, Francesca; Bufalieri, Francesca; Caimano, Miriam; Balducci, Silvia; Moretti, Marta; Romeo, Isabella; Loricchio, Elena; Maroder, Marella; Botta, Bruno; Mori, Mattia; Infante, Paola; Di Marcotullio, Lucia - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. 1518-1534 - issn: 2072-6694 - wos: WOS:000498826000115 (40) - scopus: 2-s2.0-85073503434 (40)
11573/1343151 - 2019 -
SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors Petroni, Marialaura; Sahùn Roncero, Maria; Ramponi, Valentina; Fabretti, Francesca; Nicolis Di Robilant, Vittoria; Moretti, Marta; Alfano, Vincenzo; Corsi, Alessandro; De Panfilis, Simone; Giubettini, Maria; Di Giulio, Stefano; Capalbo, Carlo; Belardinilli, Francesca; Coppa, Anna; Sardina, Francesca; Colicchia, Valeria; Pedretti, Flaminia; Infante, Paola; Cardinali, Beatrice; Tessitore, Alessandra; Canettieri, Gianluca; De Smaele, Enrico; Giannini, Giuseppe - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature
London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000508896900014 (4) - scopus: 2-s2.0-85077063979 (4)
11573/1559753 - 2019 -
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold Romeo, Isabella; Berardozzi, Simone; Bernardi, Flavia; Infante, Paola; Ingallina, Cinzia; Toscano, Sara; De Paolis, Elisa; Alfonsi, Romina; Caimano, Miriam; Botta, Bruno; Mori, Mattia; Di Marcotullio, Lucia; Ghirga, Francesca - 04f Poster
congresso: XII EWDD - 12th European Workshop in Drug Design (Certosa di Pontignano, Siena (Italy))
libro: Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold - ()
11573/1338842 - 2019 -
KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2 Spiombi, Eleonora; Angrisani, Annapaola; Fonte, Simone; De Feudis, Giuseppina; Fabretti, Francesca; Cucchi, Danilo; Izzo, Mariapaola; Infante, Paola; Miele, Evelina; Po, Agnese; Di Magno, Laura; Magliozzi, Roberto; Guardavaccaro, Daniele; Maroder, Marella; Canettieri, Gianluca; Giannini, Giuseppe; Ferretti, Elisabetta; Gulino, Alberto; Di Marcotullio, Lucia; Moretti, Marta; De Smaele, Enrico - 01a Articolo in rivista
rivista: ONCOGENESIS (London Nature Publishing Group) pp. 64- - issn: 2157-9024 - wos: WOS:000494423700001 (21) - scopus: 2-s2.0-85074354238 (22)
11573/1131161 - 2018 -
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold Berardozzi, Simone; Bernardi, Flavia; Infante, Paola; Ingallina, Cinzia; Toscano, Sara; De Paolis, Elisa; Alfonsi, Romina; Caimano, Miriam; Botta, Bruno; Mori, Mattia; Di Marcotullio, Lucia; Ghirga, Francesca - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 554-562 - issn: 0223-5234 - wos: WOS:000443663200039 (33) - scopus: 2-s2.0-85049903501 (33)
11573/1051225 - 2018 -
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61 Calcaterra, Andrea; Iovine, Valentina; Botta, Bruno; Quaglio, Deborah; D’Acquarica, Ilaria; Ciogli, Alessia; Iazzetti, Antonia; Alfonsi, Romina; Lospinoso Severini, Ludovica; Infante, Paola; Di Marcotullio, Lucia; Mori, Mattia; Ghirga, Francesca - 01a Articolo in rivista
rivista: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 349-358 - issn: 1475-6366 - wos: WOS:000423413000001 (44) - scopus: 2-s2.0-85041293877 (49)
11573/1085264 - 2018 -
Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis Infante, Paola; Faedda, Roberta; Bernardi, Flavia; Bufalieri, Francesca; Lospinoso Severini, Ludovica; Alfonsi, Romina; Mazzà, Daniela; Siler, Mariangela; Coni, Sonia; Po, Agnese; Petroni, Marialaura; Ferretti, Elisabetta; Mori, Mattia; De Smaele, Enrico; Canettieri, Gianluca; Capalbo, Carlo; Maroder, Marella; Screpanti, Isabella; Kool, Marcel; Pfister, Stefan M.; Guardavaccaro, Daniele; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
rivista: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. ...-... - issn: 2041-1723 - wos: WOS:000426899000002 (47) - scopus: 2-s2.0-85044632076 (50)
11573/1258520 - 2018 -
Natural products inspired modulators of cancer stem cells-specific signaling pathways notch and hedgehog Palermo, Rocco; Ghirga, Francesca; Piccioni, Maria Grazia; Bernardi, Flavia; Zhdanovskaya, Nadezda; Infante, Paola; Mori, Mattia - 01g Articolo di rassegna (Review)
rivista: CURRENT PHARMACEUTICAL DESIGN (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 4251-4269 - issn: 1381-6128 - wos: WOS:000458726500004 (21) - scopus: 2-s2.0-85063684783 (29)
11573/1206569 - 2018 -
MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors Petroni, Marialaura; Sardina, Francesca; Infante, Paola; Bartolazzi, Armando; Locatelli, Erica; Fabretti, Francesca; Di Giulio, Stefano; Capalbo, Carlo; Cardinali, Beatrice; Coppa, Anna; Tessitore, Alessandra; Colicchia, Valeria; Sahùn Roncero, Maria; Belardinilli, Francesca; Di Marcotullio, Lucia; Soddu, Silvia; Comes Franchini, Mauro; Petricci, Elena; Gulino, Alberto; Giannini, Giuseppe - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. 895- - issn: 2041-4889 - wos: WOS:000444826200010 (37) - scopus: 2-s2.0-85052686149 (37)
11573/960059 - 2017 -
Polymeric glabrescione B nanocapsules for passive targeting of Hedgehog-dependent tumor therapy in vitro Ingallina, Cinzia; Costa, Pedro M; Ghirga, Francesca; Klippstein, Rebecca; Wang, Julie T; Berardozzi, Simone; Hodgins, Naomi; Infante, Paola; Pollard, Steven M; Botta, Bruno; Al Jamal, Khuloud T. - 01a Articolo in rivista
rivista: NANOMEDICINE (London : Future Medicine, 2006-) pp. 711-728 - issn: 1743-5889 - wos: WOS:000397722200002 (25) - scopus: 2-s2.0-85016410326 (27)
11573/1024175 - 2017 -
β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells Miele, Evelina; Po, Agnese; Begalli, Federica; Antonucci, Laura; Mastronuzzi, Angela; Marras, Carlo Efisio; Carai, Andrea; Cucchi, Danilo; Abballe, Luana; Besharat, Zein Mersini; Catanzaro, Giuseppina; Infante, Paola; Di Marcotullio, Lucia; Canettieri, Gianluca; De Smaele, Enrico; Screpanti, Isabella; Locatelli, Franco; Ferretti, Elisabetta - 01a Articolo in rivista
rivista: BMC CANCER (London: BioMed Central, [2001]-) pp. 488- - issn: 1471-2407 - wos: WOS:000405865300002 (54) - scopus: 2-s2.0-85024120271 (55)
11573/863407 - 2016 -
The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint Di Magno, Laura; Basile, Alessio; Coni, Sonia; Manni, Simona; Sdruscia, Giulia; D'amico, Davide; Antonucci, Laura; Infante, Paola; De Smaele, Enrico; Cucchi, Danilo; Ferretti, Elisabetta; Di Marcotullio, Lucia; Screpanti, Isabella; Canettieri, Gianluca - 01a Articolo in rivista
rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 9538-9549 - issn: 1949-2553 - wos: WOS:000375618100081 (39) - scopus: 2-s2.0-84961627529 (40)
11573/901391 - 2016 -
Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype Infante, Paola; Alfonsi, Romina; Ingallina, Cinzia; Quaglio, Deborah; Ghirga, Francesca; D'acquarica, Ilaria; Bernardi, Flavia; Di Magno, Laura; Canettieri, Gianluca; Screpanti, Isabella; Gulino, Alberto; Botta, Bruno; Mori, Mattia; Di Marcotullio, Lucia - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000387968100003 (50) - scopus: 2-s2.0-84992361773 (50)
11573/913369 - 2016 -
SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development Raducu, Madalina; Fung, Ella; Serres, Sébastien; Infante, Paola; Barberis, Alessandro; Fischer, Roman; Bristow, Claire; Thézénas, Marie Laëtitia; Finta, Csaba; Christianson, John C; Buffa, Francesca M; Kessler, Benedikt M; Sibson, Nicola R; Di Marcotullio, Lucia; Toftgård, Rune; D'angiolella, Vincenzo - 01a Articolo in rivista
rivista: EMBO JOURNAL (attuale:
NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707
Precedente:
Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 1400-1416 - issn: 0261-4189 - wos: WOS:000378929900004 (48) - scopus: 2-s2.0-84977560736 (50)
11573/871953 - 2015 -
Click reaction as a tool to combine pharmacophores: The case of Vismodegib Christodoulou, Michael S; Mori, Mattia; Pantano, Rebecca; Alfonsi, Romina; Infante, Paola; Botta, Maurizio; Damia, Giovanna; Ricci, Francesca; Sotiropoulou, Panagiota A.; Liekens, Sandra; Botta, Bruno; Passarella, Daniele - 01a Articolo in rivista
rivista: CHEMPLUSCHEM (Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim) pp. 938-943 - issn: 2192-6506 - wos: WOS:000355263100005 (23) - scopus: 2-s2.0-84934875860 (24)
11573/808783 - 2015 -
Non-canonical Hedgehog/ampk-mediated control of polyamine metabolism supports neuronal and medulloblastoma cell growth D'amico, Davide; Antonucci, Laura; Di Magno, Laura; Coni, Sonia; Sdruscia, Giulia; Macone, Alberto; Miele, Evelina; Infante, Paola; Di Marcotullio, Lucia; De Smaele, Enrico; Ferretti, Elisabetta; Ciapponi, Laura; Giangaspero, Felice; John, R. Yates Iii; Agostinelli, Enzo; Cardinali, Beatrice; Screpanti, Isabella; Gulino, Alberto; Canettieri, Gianluca - 01a Articolo in rivista
rivista: DEVELOPMENTAL CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 21-35 - issn: 1534-5807 - wos: WOS:000363076000008 (62) - scopus: 2-s2.0-84945252145 (63)
11573/871963 - 2015 -
Targeting GLI factors to inhibit the Hedgehog pathway Infante, Paola; Alfonsi, Romina; Botta, Bruno; Mori, Mattia; Di Marcotullio, Lucia - 01a Articolo in rivista
rivista: TRENDS IN PHARMACOLOGICAL SCIENCES (Elsevier Trends Journals:An Imprint of Elsevier Science Limited, The Boulevard, Langford Lane, Kidlington, Oxford 0X5 1GB United Kingdom:011 44 1865 843000, 011 44 1865 843699, Fax: 011 44 1865 843010) pp. 547-558 - issn: 0165-6147 - wos: WOS:000359879100009 (96) - scopus: 2-s2.0-84938953364 (99)
11573/871967 - 2015 -
Insights into gli factors ubiquitylation methods Infante, Paola; Alfonsi, Romina; Di Marcotullio, Lucia - 02a Capitolo o Articolo
libro: Methods in Molecular Biology - (978-1-4939-2771-5; 978-1-4939-2772-2; 978-1-4939-2771-5; 978-1-4939-2772-2)
11573/649688 - 2015 -
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors Infante, Paola; Mori, Mattia; Alfonsi, Romina; Ghirga, Francesca; Federica, Aiello; Toscano, Sara; Ingallina, Cinzia; Mariangela, Siler; Cucchi, Danilo; Po, Agnese; Miele, Evelina; Davide, D’Amico; Canettieri, Gianluca; De Smaele, Enrico; Ferretti, Elisabetta; Screpanti, Isabella; Gloria Uccello, Barretta; Maurizio, Botta; Botta, Bruno; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
rivista: EMBO JOURNAL (attuale:
NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707
Precedente:
Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 200-217 - issn: 0261-4189 - wos: WOS:000347878900008 (148) - scopus: 2-s2.0-84921293370 (152)
11573/648414 - 2014 -
Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth Di Magno, Laura; Daniela, Manzi; D'amico, Davide; Coni, Sonia; Macone, Alberto; Infante, Paola; Di Marcotullio, Lucia; De Smaele, Enrico; Ferretti, Elisabetta; Screpanti, Isabella; Agostinelli, Enzo; Gulino, Alberto; Canettieri, Gianluca - 01a Articolo in rivista
rivista: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 3404-3413 - issn: 1538-4101 - wos: WOS:000348313100013 (39) - scopus: 2-s2.0-84915795126 (40)
11573/649690 - 2014 -
Yin-Yang strands of PCAF/Hedgehog axis in cancer control Infante, Paola; Canettieri, Gianluca; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
rivista: TRENDS IN MOLECULAR MEDICINE (London: Elsevier Science, 2001-) pp. 416-418 - issn: 1471-4914 - wos: WOS:000340303300002 (14) - scopus: 2-s2.0-84905115865 (13)
11573/543166 - 2013 -
Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy Coni, Sonia; Antonucci, Laura; D'amico, Davide; Di Magno, Laura; Infante, Paola; De Smaele, Enrico; Giannini, Giuseppe; Di Marcotullio, Lucia; Screpanti, Isabella; Gulino, Alberto; Canettieri, Gianluca - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e65718- - issn: 1932-6203 - wos: WOS:000321099000097 (59) - scopus: 2-s2.0-84878804952 (61)
11573/695912 - 2013 -
Control of stem cells and cancer stem cells by Hedgehog signaling: Pharmacologic clues from pathway dissection Coni, Sonia; Infante, Paola; Gulino, Alberto - 01a Articolo in rivista
rivista: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited
-London ; New York : Pergamon Press, 1958-) pp. 623-628 - issn: 0006-2952 - wos: WOS:000315004400005 (43) - scopus: 2-s2.0-84873405096 (50)
11573/527314 - 2013 -
microRNA-17-92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1 Garg, Neha; Po, Agnese; Miele, Evelina; Campese, Antonio Francesco; Begalli, Federica; Marianna, Silvano; Infante, Paola; Capalbo, Carlo; De Smaele, Enrico; Canettieri, Gianluca; Di Marcotullio, Lucia; Screpanti, Isabella; Ferretti, Elisabetta; Gulino, Alberto - 01a Articolo in rivista
rivista: EMBO JOURNAL (attuale:
NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707
Precedente:
Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 2819-2832 - issn: 0261-4189 - wos: WOS:000326504900006 (56) - scopus: 2-s2.0-84887046837 (56)
11573/527250 - 2013 -
PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress Mazza, Daniele; Infante, Paola; Colicchia, Valeria; Greco, Azzura; Alfonsi, Romina; M., Siler; Antonucci, Laura; Po, Agnese; De Smaele, Enrico; Ferretti, Elisabetta; Capalbo, Carlo; Bellavia, Diana; Canettieri, Gianluca; Giannini, Giuseppe; Screpanti, Isabella; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
rivista: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 1688-1697 - issn: 1350-9047 - wos: WOS:000327010600012 (75) - scopus: 2-s2.0-84887619992 (83)
11573/690929 - 2013 -
“Natural lead products inhibit the Hedgehog signaling pathway in medulloblastoma”. Toscano, S.; Ingallina, Cinzia; Ghirga, Francesca; Infante, P.; Di Marcotullio, L.; Gulino, A.; Mori, M.; Botta, M. - 04f Poster
congresso: [COST] Action CM1106 - “Working Group meeting in Porto (University of Porto Ipatimup, Porto)
11573/628182 - 2013 -
Natural Products to Drugs: New Sonic Hedgehog Pathway Inhibitors in Meduloblastoma Toscano, Sara; Mascarello, A.; Nisticò, E.; Botta, Bruno; Infante, P.; Mori, M. - 04d Abstract in atti di convegno
congresso: COST Action CM1106 2nd Working Group Meeting "Chemical Approaches to Targeting Drug Resistance in Cancer Stem Cells" (Warsaw (Poland))
libro: Abstract Book - ()
11573/690909 - 2012 -
Natural products as Hedgehog signaling pathway inhibitors Toscano, S.; Ingallina, Cinzia; Ghirga, Francesca; Calcaterra, A.; Infante, P.; Di Marcotullio, L.; Gulino, A.; Mori, M.; Botta, M. - 04f Poster
congresso: [COST] Action CM0804 – “Chemistry and Target Identification of Natural Products” (Romanian Academy, Bucharest)
11573/690912 - 2012 -
“Natural products as Hedgehog signaling pathway inhibitors” Toscano, S.; Ingallina, Cinzia; Ghirga, Francesca; Calcaterra, A.; Infante, P.; Di Marcotullio, L.; Gulino, A.; Mori, M.; Botta, M. - 04f Poster
congresso: XXXVII A. Corbella Summer School Seminars in Organic Synthesis (Gargnano (BS))
11573/690918 - 2012 -
“Small molecules derived from plants as Hedgehog signaling pathway inhibitors” Toscano, S.; Ingallina, Cinzia; Ghirga, Francesca; Calcaterra, A.; Infante, P.; Di Marcotullio, L.; Gulino, A.; Mori, M.; Botta, M. - 04f Poster
congresso: [COST] Action CM1106 -“Chemical Approaches to targeting Drug Resistance in Cancer Stem Cells” (Università degli Studi di Milano)
11573/690883 - 2011 -
Natural products as Hedgehog signaling pathway inhibitors Calcaterra, A.; Ghirga, Francesca; Mascarello, A.; Infante, P.; Di Marcotullio, L.; Gulino, A.; Mori, M.; Botta, M. - 04f Poster
congresso: : “Natural products as Hedgehog signaling pathway inhibitors”. [COST ] Action CM08004 meeting (Dublino (Irlanda))
11573/377914 - 2011 -
Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma De Smaele, Enrico; Di Marcotullio, Lucia; Moretti, Marta; Pelloni, Marianna; Occhione, Maria Anna; Infante, Paola; Cucchi, Danilo; Greco, Azzura; Pietrosanti, Laura; J., Todorovic; Coni, Sonia; Canettieri, Gianluca; Ferretti, Elisabetta; R., Bei; Maroder, Marella; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
rivista: NEOPLASIA (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 374-385 - issn: 1522-8002 - wos: WOS:000289529400009 (78) - scopus: 2-s2.0-79952438480 (80)
11573/360864 - 2011 -
Protected from the inside: Endogenous histone deacetylase inhibitors and the road to cancer Di Marcotullio, Lucia; Canettieri, Gianluca; Infante, Paola; Greco, Azzura; Gulino, Alberto - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (Elsevier Scientific Publ. Co.) pp. 241-252 - issn: 0304-419X - wos: WOS:000289020200009 (43) - scopus: 2-s2.0-79951713773 (46)
11573/377915 - 2011 -
Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal Di Marcotullio, Lucia; Greco, Azzura; Mazza', Daniela; Canettieri, Gianluca; Pietrosanti, Laura; Infante, Paola; Coni, Sonia; Moretti, Marta; De Smaele, Enrico; Ferretti, Elisabetta; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 65-76 - issn: 0950-9232 - wos: WOS:000285959300006 (92) - scopus: 2-s2.0-78650983824 (95)
11573/690887 - 2011 -
Natural products as Hedgehog signaling pathway inhibitors Ingallina, Cinzia; Ghirga, Francesca; Calcaterra, A.; Mascarello, A.; Infante, P.; Di Marcotullio, L.; Gulino, A.; Mori, M.; Botta, M. - 04f Poster
congresso: ESF Research Conference on Natural Products Chemistry, Biology and Medicine IV (Acquafredda di Maratea)
11573/401408 - 2010 -
Histone deacetylase and Cullin3-REN KCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation Canettieri, Gianluca; Di Marcotullio, Lucia; Greco, Azzura; Coni, Sonia; Antonucci, Laura; Infante, Paola; Pietrosanti, Laura; De Smaele, Enrico; Ferretti, Elisabetta; Miele, Evelina; Pelloni, Marianna; Giuseppina De, Simone; Emilia Maria, Pedone; Paola, Gallinari; Giorgi, Alessandra; Christian, Steinkuhler; Luigi, Vitagliano; Carlo, Pedone; Schinina', Maria Eugenia; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
rivista: NATURE CELL BIOLOGY (Nature America Incorporated:345 Park Avenue South, 6th Floor:New York, NY 10010:(888)331-6288, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: (212)689-9108) pp. 132-U91 - issn: 1465-7392 - wos: WOS:000274139400007 (284) - scopus: 2-s2.0-75949106376 (290)