NOEMI MARTINA CANTALE AEO

PhD Student

PhD program:: XXXIX
email: noemimartina.cantaleaeo@uniroma1.it
phone: 0649255673
building: Dipartimento di Medicina Molecolare, Edificio RM110, Palazzina B
room: 4° piano - stanza 404

supervisor: Prof.re Antonio Francesco Campese
advisor: Prof.re Antonio Francesco Campese
co-supervisor: Prof.re Giuseppe Giannini

EDUCATION AND TRAINING
1/11/2023-ongoing: PhD student in Molecular Medicine
University of Rome “La Sapienza”, Piazzale Aldo Moro 5, 00185, Rome (Italia)

03/10/2022-18/10/2023: Experimental Thesis
Department of Experimental Medicine, Viale Regina Elena 291, 00161, Rome (Italia)

1/10/2020-18/10/2023: Master’s Degree in Genetics e Molecular Biology with a grade of 107/110
University of Rome “La Sapienza”, Piazzale Aldo Moro 5, 00185, Rome (Italia)
Thesis in “ Study of the interaction between “myeloid-derived suppressor cells” (MDSC) and “Natural Killer” cells (NK) in the tumor microenvironment of Notch 3 receptor-dependet T- cell Acute Lymphoblastic Leukemia (T-ALL)”

01/10/2016-21/07/2020: Bachelor’s Degree in Biological Sciences with a grade of 108/110
University of “Università di Catania, piazza Università 2, 95131, Catania (Italia)
Thesis in “ Liquid tissue biopsy”

2010-2015: Five-year Diploma
Liceo Classico “Don Bosco”, via Cifali 5, 95100 Catania (Italia)

Relevant skills:
* Staining and analysis of cell samples by Flow-cytometry (BD Symphony) and FlowJo
* Cell sample treatments and analysis using the Celigo Image Cytometer.
* Experience in vitro and in vivo suppression assays
* Separation of cell populations from peripheral blood and murine organs, by both magnetic bead's protocols and FACS-assisted cell sorting experiments
* Perform with tissues from genetically modified mouse models
* Knowledge and experience with RNA/DNA and protein extraction
* PCR,qPCR assays and analysis
* Expertise in cell culture and basic cellular and molecular biology techniques
* Demonstrated expertise in performing Chromatin Immunoprecipitation (ChIP) methodologies, proficiently investigating chromatin modifications and protein-DNA interactions

Research products

11573/1760298 - 2025 - Opposite effects of spermidine and GC7 in cell culture are dictated by distinct molecular targets

Tahara, T.; Bordone, R.; Campese, A. F.; Cantale Aeo, N. M.; Astolfi, R.; Coni, S.; Ragno, R.; Canettieri, G.; Agostinelli, E. - 01a Articolo in rivista

paper: BIOCHEMICAL JOURNAL (London: Portland Press Limited London: Biochemical Society, 1984-) pp. 1973-1992 - issn: 0264-6021 - wos: WOS:001645149500010 (0) - scopus: 2-s2.0-105025171787 (0)

11573/1729233 - 2024 - Notch inhibitors and BH3 mimetics in T-cell acute lymphoblastic leukemia

Sergio, Ilaria; Varricchio, Claudia; Squillante, Federica; Cantale Aeo, Noemi Martina; Campese, Antonio Francesco; Felli, Maria Pia - 01g Articolo di rassegna (Review)

paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:001377194600001 (3) - scopus: 2-s2.0-85211824937 (3)

11573/1721694 - 2024 - The NF-κB1/p50 subunit influences the Notch/IL-6-driven expansion of Myeloid-Derived Suppressor Cells in murine T-Cell Acute Lymphoblastic Leukemia

Abdollahzadeh, B.; Cantale Aeo, N. M.; Giordano, N.; Orlando, A.; Basciani, M.; Peruzzi, G.; Grazioli, P.; Screpanti, I.; Felli, M. P.; Campese, A. F. - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-15 - issn: 1422-0067 - wos: WOS:001323137700001 (0) - scopus: 2-s2.0-85205235833 (0)