NICOLE FRATINI

PhD Student

PhD program:: XXXIX
email: nicole.fratini@uniroma1.it
phone: 02 00660305
building: Istituto Nazionale di Genetica Molecolare (INGM)-Fondazione Invernizzi Milano
room: 325

supervisor: Claudia Bearzi
advisor: Saula Checquolo

Research: Patient-specific bioprinted organoids: an innovative model to study the role of the Notch pathway in female-specific cancers chemoresistance

WORKPLACE:
National Institute of Molecular Genetics (INGM) - Fondazione Invernizzi; Milano (Italia)

SUPERVISOR/S:
Claudia Bearzi

PREVIOUS RESEARCH EXPERIENCE:
02/2022-07/2023 Master's degree internship:
CCBIL-Comparative Cell Biology and Imaging Laboratory, Department of biology and biotechnology Charles Darwin (Sapienza, Roma)
- Role of extracellular vesicles in pathophysiological contexts and as drug delivery systems;
- Collagen-based scaffold for macrophage polarization to create an in vitro model for the study of atherosclerosis.
THESIS TITLE: Role of extracellular vesicles in the progression of Amyotrophic Lateral Sclerosis.

03/2021-07/2021 Bachelor's degree internship:
Department of Molecular Medicine (Sapienza, Roma)
THESIS TITLE: Immunomodulatory effects of neddylation inhibition in multiple myeloma: expression of Natural Killer cell activating ligands.

EDUCATION AND TRAINING:
27/07/2023 Master's degree in Medical Biotechnology - Bioengineering curriculum
Sapienza Università di Roma
Piazzale Aldo Moro, 5, 00185 Roma (Italia)

14/07/2021 Bachelor's degree in Biotechnology
Sapienza Università di Roma
Piazzale Aldo Moro, 5, 00185 Roma (Italia)

07/2018 High school leaving qualification in scientific studies
Liceo Scientifico Ettore Majorana
Via Roma, 298, 00012 Guidonia Montecelio (RM)

Research products

11573/1734146 - 2025 - Mimicking the dystrophic cardiac extracellular environment through DystroGel

Chirivì, Maila; Maiullari, Fabio; Milan, Marika; Ceraolo, Maria Grazia; Fratini, Nicole; Fasciani, Alessandra; Bousselmi, Salma; Stirm, Michael; Scalera, Francesca; Gervaso, Francesca; Villa, Michela; Viganò, Raffaello; Brambilla, Francesca; Mauri, Pierluigi; De Falco, Elena; Silvestre, Dario Di; Costantini, Marco; Wolf, Eckhard; Bearzi, Claudia; Rizzi, Roberto - 01a Articolo in rivista

paper: ADVANCED HEALTHCARE MATERIALS (Weinheim : Wiley-VCH) pp. - - issn: 2192-2659 - wos: (0) - scopus: (0)

11573/1733418 - 2025 - Bioactive hydrogel supplemented with stromal cell-derived extracellular vesicles enhance wound healing

Galbiati, Matteo; Maiullari, Fabio; Ceraolo, Maria Grazia; Bousselmi, Salma; Fratini, Nicole; Gega, Klajdi; Recchia, Sandro; Ferretti, Anna Maria; Scala, Giovanni; Costantini, Marco; Sciarra, Tommaso; Rizzi, Roberto; Bearzi, Claudia - 01a Articolo in rivista

paper: PHARMACEUTICS (Basel: MDPI, 2009-) pp. - - issn: 1999-4923 - wos: (0) - scopus: (0)

11573/1717509 - 2024 - Enhancing neovascularization post-myocardial infarction through injectable hydrogel functionalized with endothelial-derived EVs

Maiullari, F.; Milan, M.; Chirivi, M.; Ceraolo, M. G.; Bousselmi, S.; Fratini, N.; Galbiati, M.; Fortunato, O.; Costantini, M.; Brambilla, F.; Mauri, P.; Di Silvestre, D.; Calogero, A.; Sciarra, T.; Rizzi, R.; Bearzi, C. - 01a Articolo in rivista

paper: BIOFABRICATION (Bristol : IOP Publishing) pp. - - issn: 1758-5090 - wos: WOS:001274470400001 (0) - scopus: 2-s2.0-85199566034 (1)

11573/1727380 - 2024 - Macrophages producing chondroitin sulfate proteoglycan‐4 induce neuro‐cardiac junction impairment in Duchenne muscular dystrophy

Milan, Marika; Maiullari, Fabio; Chirivì, Maila; Ceraolo, Maria Grazia; Zigiotto, Rebecca; Soluri, Andrea; Maiullari, Silvia; Landoni, Elisa; Silvestre, Dario Di; Brambilla, Francesca; Mauri, Pierluigi; De Paolis, Veronica; Fratini, Nicole; Crosti, Maria Cristina; Cordiglieri, Chiara; Parisi, Chiara; Calogero, Antonella; Seliktar, Dror; Torrente, Yvan; Lanzuolo, Chiara; Dotti, Gianpietro; Toccafondi, Mirco; Bombaci, Mauro; De Falco, Elena; Bearzi, Claudia; Rizzi, Roberto - 01a Articolo in rivista

paper: JOURNAL OF PATHOLOGY (John Wiley & Sons Limited:1 Oldlands Way, Bognor Regis, P022 9SA United Kingdom:011 44 1243 779777, EMAIL: cs-journals@wiley.co.uk, INTERNET: http://www.wiley.co.uk, Fax: 011 44 1243 843232) pp. - - issn: 0022-3417 - wos: (0) - scopus: 2-s2.0-85208788437 (0)