11573/1613665 - 2021 -
Drug delivery systems for hedgehog inhibitors in the treatment of SHH-medulloblastoma Caimano, M.; Lospinoso Severini, L.; Loricchio, E.; Infante, P.; Di Marcotullio, L. - 01g Articolo di rassegna (Review)
rivista: FRONTIERS IN CHEMISTRY (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-2646 - wos: WOS:000663813400001 (13) - scopus: 2-s2.0-85108348605 (13)
11573/1613699 - 2021 -
A new smoothened antagonist bearing the purine scaffold shows antitumour activity in vitro and in vivo Zarate, A. M.; Espinosa-Bustos, C.; Guerrero, S.; Fierro, A.; Oyarzun-Ampuero, F.; Quest, A. F. G.; Di Marcotullio, L.; Loricchio, E.; Caimano, M.; Calcaterra, A.; Gonzalez-Quiroz, M.; Aguirre, A.; Melendez, J.; Salas, C. O. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000690546100001 (11) - scopus: 2-s2.0-85111760377 (11)
11573/1384478 - 2020 -
The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i Bufalieri, F.; Caimano, M.; Severini, L. L.; Basili, I.; Paglia, F.; Sampirisi, L.; Loricchio, E.; Petroni, M.; Canettieri, G.; Santoro, A.; D'angelo, L.; Infante, P.; Di Marcotullio, L. - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. 321- - issn: 2072-6694 - wos: WOS:000522477300067 (42) - scopus: 2-s2.0-85079068523 (40)
11573/1560331 - 2020 -
Dubs activating the hedgehog signaling pathway: a promising therapeutic target in cancer Bufalieri, F.; Lospinoso Severini, L.; Caimano, M.; Infante, P.; Di Marcotullio, L. - 01g Articolo di rassegna (Review)
rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000549233900001 (11) - scopus: 2-s2.0-85086322190 (17)
11573/1559760 - 2020 -
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold Romeo, Isabella; Lospinoso Severini, Ludovica; Quaglio, Deborah; Basili, Irene; Ghirga, Francesca; Bufalieri, Francesca; Caimano, Miriam; Balducci, Silvia; Moretti, Marta; Loricchio, Elena; Maroder, Marella; Botta, Bruno; Mori, Mattia; Infante, Paola; Di Marcotullio, Lucia - 04f Poster
congresso: STRATAGEM COST CA17104: New diagnostic and therapeutic tools against multidrug resistant tumors (virtual meeting - online mode)
libro: Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold - ()
11573/1210601 - 2019 -
Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation Antonucci, Laura; Di Magno, Laura; D'amico, Davide; Manni, Simona; Serrao, Silvia Maria; Di Pastena, Fiorella; Bordone, Rosa; Yurtsever, Zuleyha Nihan; Caimano, Miriam; Petroni, Marialaura; Giorgi, Alessandra; Schininà, Maria Eugenia; Yates Iii, John R; Di Marcotullio, Lucia; De Smaele, Enrico; Checquolo, Saula; Capalbo, Carlo; Agostinelli, Enzo; Maroder, Marella; Coni, Sonia; Canettieri, Gianluca - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF ONCOLOGY (National Hellenic Research Foundation:48 Vas Constatinou Avenue, Athens 11635 Greece:011 30 1 7241505, Fax: 011 30 1 7241505Editore attuale:PROFESSOR D A SPANDIDOS, 1, S MERKOURI ST, EDITORIAL OFFICE,, ATHENS, GREECE, 116 35.
Editore precedente:Editorial Academy of the International Journal of Oncology.) pp. 505-514 - issn: 1019-6439 - wos: WOS:000454923900009 (25) - scopus: 2-s2.0-85058877986 (27)
11573/1304369 - 2019 -
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP Bufalieri, F.; Infante, P.; Bernardi, F.; Caimano, M.; Romania, P.; Moretti, M.; Lospinoso Severini, L.; Talbot, J.; Melaiu, O.; Tanori, M.; Di Magno, L.; Bellavia, D.; Capalbo, C.; Puget, S.; De Smaele, E.; Canettieri, G.; Guardavaccaro, D.; Busino, L.; Peschiaroli, Angelo; Pazzaglia, S.; Giannini, G.; Melino, G.; Locatelli, F.; Gulino, A.; Ayrault, O.; Fruci, D.; Di Marcotullio, L. - 01a Articolo in rivista
rivista: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. 1-15 - issn: 2041-1723 - wos: WOS:000476877400003 (40) - scopus: 2-s2.0-85069646549 (41)
11573/1321077 - 2019 -
A Smo/Gli multitarget hedgehog pathway inhibitor impairs tumor growth Lospinoso Severini, Ludovica; Quaglio, Deborah; Basili, Irene; Ghirga, Francesca; Bufalieri, Francesca; Caimano, Miriam; Balducci, Silvia; Moretti, Marta; Romeo, Isabella; Loricchio, Elena; Maroder, Marella; Botta, Bruno; Mori, Mattia; Infante, Paola; Di Marcotullio, Lucia - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. 1518-1534 - issn: 2072-6694 - wos: WOS:000498826000115 (39) - scopus: 2-s2.0-85073503434 (40)
11573/1559753 - 2019 -
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold Romeo, Isabella; Berardozzi, Simone; Bernardi, Flavia; Infante, Paola; Ingallina, Cinzia; Toscano, Sara; De Paolis, Elisa; Alfonsi, Romina; Caimano, Miriam; Botta, Bruno; Mori, Mattia; Di Marcotullio, Lucia; Ghirga, Francesca - 04f Poster
congresso: XII EWDD - 12th European Workshop in Drug Design (Certosa di Pontignano, Siena (Italy))
libro: Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold - ()
11573/1131161 - 2018 -
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold Berardozzi, Simone; Bernardi, Flavia; Infante, Paola; Ingallina, Cinzia; Toscano, Sara; De Paolis, Elisa; Alfonsi, Romina; Caimano, Miriam; Botta, Bruno; Mori, Mattia; Di Marcotullio, Lucia; Ghirga, Francesca - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 554-562 - issn: 0223-5234 - wos: WOS:000443663200039 (33) - scopus: 2-s2.0-85049903501 (32)