MICHELA DE MEO

PhD Student

PhD program:: XXXVIII
email: michela.demeo@uniroma1.it
phone: 0649918299
building: Istituto di Patologia Generale (PL038), Policlinico Umberto I, Viale Regina Elena 324
room: LAB-1




supervisor: Dott.ssa Chiara Nicolazzo
advisor: Prof.ssa Paola Gazzaniga

Research: Liquid biopsy applications to precision oncology for solid tumors: 3D coltures from tumor cells and development of multi-analyte test on blood and non-blood body fluids.

Liquid biopsy applications to precision oncology for solid tumors: 3D coltures from tumor cells and development of multi-analyte test on blood and non-blood body fluids.

CURRENT POSITION
PhD student in Molecular Medicine at the Laboratory of Liquid Biopsy of tumors directed by Prof. P. Gazzaniga.

WORK ADDRESS: Institute of General Pathology (PL038), Umberto I Polyclinic, Viale Regina Elena, 324.

CAREER
11/12/2023 – 14/12/2023 CERTIFICATE OF RECOGNITION FOR ATTENDING THE CELLSEARCH® FULL SYSTEM TRAINING
MENARINI Silicon Biosystems Spa
20/09/2023 – 23/09/2023 – Skiathos Island, Greece
6th Advances in Circulating Tumor Cells: “Liquid Biopsy and Precision Oncology: Where do we stand now?" Oral Presentation "Genomic landscape and survival analysis of ctDNA “neo-RAS wild-type” patients with originally RAS mutant metastatic colorectal cancer"
20/05/2023 – Policlinico Umberto I, Roma
"ECCELLENZA DEL FUTURO: TRA SALUTE, NUOVI MODELLI E NUOVE TECNOLOGIE" Oral Presentation "Expansion and culture of circulating tumor cells in vitro as a clinical and preclinical tool in precision oncology"
2022: winner of the Rome Technopole/National Centers PhD scholarship - DM 351 at the Department of Molecular Medicine at Sapienza University of Rome;
2022: Achievement of qualification for the profession of Pharmacist;
2022: Master's Degree in Pharmacy at Sapienza University of Rome.

SKILLS
- Mutational analysis of circulating DNA from peripheral blood of patients with solid tumors;
- Molecular characterization of circulating tumor cells isolated from patients with solid tumors;
-Primary and secondary cell cultures for the analysis of drug resistance mechanisms to chemotherapy and targeted therapies;
- CellSearch Certificated Operator

Research products

11573/1725338 - 2024 - Exploring the utility of a NGS multigene panel to predict BCG response in patients with non-muscle invasive bladder cancer
Belardinilli, Francesca; Meo, Michela De; Giudice, Francesco Del; Scornajenghi, Carlo Maria; Gazzaniga, Paola; Berardinis, Ettore De; Marino, Luca; Magliocca, Fabio Massimo; Chung, Benjamin Inbeh; Łaszkiewicz, Jan; Magri, Valentina; Giannini, Giuseppe; Nicolazzo, Chiara - 01a Articolo in rivista
paper: ONCOLOGY RESEARCH (New York NY: Elsevier Science Pub. Co.) pp. 1-10 - issn: 1555-3906 - wos: (0) - scopus: (0)

11573/1707559 - 2024 - Circulating Cancer-Associated Macrophage-like Cells as a Blood-Based Biomarker of Response to Immune Checkpoint Inhibitors
Magri, Valentina; De Renzi, Gianluigi; Marino, Luca; De Meo, Michela; Siringo, Marco; Gelibter, Alain; Gareri, Roberta; Cataldi, Chiara; Giannini, Giuseppe; Santini, Daniele; Nicolazzo, Chiara; Gazzaniga, Paola - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:001201513300001 (1) - scopus: 2-s2.0-85190387529 (1)

11573/1701235 - 2024 - Early Detection of Disease Progression in Metastatic Cancers: Could CTCs Improve RECIST Criteria?
Magri, Valentina; Marino, Luca; De Renzi, Gianluigi; De Meo, Michela; Salvatori, Francesca; Buccilli, Dorelsa; Bianco, Vincenzo; Santini, Daniele; Nicolazzo, Chiara; Gazzaniga, Paola - 01a Articolo in rivista
paper: BIOMEDICINES (Basel: MDPI) pp. - - issn: 2227-9059 - wos: WOS:001170598500001 (0) - scopus: (0)

11573/1724038 - 2024 - Blood Extracellular Vesicles beyond Circulating Tumour Cells: A Valuable Risk Stratification Biomarker in High-Risk Non-Muscle-Invasive Bladder Cancer Patients
Magri, Valentina; Marino, Luca; Del Giudice, Francesco; De Meo, Michela; Siringo, Marco; De Berardinis, Ettore; Gandini, Orietta; Santini, Daniele; Nicolazzo, Chiara; Gazzaniga, Paola - 01a Articolo in rivista
paper: BIOMEDICINES (Basel: MDPI) pp. - - issn: 2227-9059 - wos: (0) - scopus: (0)

11573/1677825 - 2023 - Prognostic role of circulating tumor cell trajectories in metastatic colorectal cancer
Magri, Valentina; Marino, Luca; Nicolazzo, Chiara; Gradilone, Angela; De Renzi, Gianluigi; De Meo, Michela; Gandini, Orietta; Sabatini, Arianna; Santini, Daniele; Cortesi, Enrico; Gazzaniga, Paola - 01a Articolo in rivista
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000981003000001 (8) - scopus: 2-s2.0-85154549872 (11)

11573/1676520 - 2023 - Genomic landscape and survival analysis of ctDNA “neo-RAS wild-type” patients with originally RAS mutant metastatic colorectal cancer
Nicolazzo, Chiara; Magri, Valentina; Marino, Luca; Belardinilli, Francesca; Di Nicolantonio, Federica; De Renzi, Gianluigi; Caponnetto, Salvatore; De Meo, Michela; Giannini, Giuseppe; Santini, Daniele; Cortesi, Enrico; Gazzaniga, Paola - 01a Articolo in rivista
paper: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. - - issn: 2234-943X - wos: WOS:000967545800001 (8) - scopus: 2-s2.0-85153408588 (8)

11573/1650652 - 2022 - In vitro cultures of circulating tumor cells: a potential tool to unravel drug sensitivity
De Renzi, G.; De Marco, G.; De Meo, M.; Del Rosso, E.; Gazzaniga, P.; Nicolazzo, C. - 01g Articolo di rassegna (Review)
paper: CANCER DRUG RESISTANCE (Alhambra CA: OAE Publishing Inc., 2018-) pp. 245-260 - issn: 2578-532X - wos: WOS:000849626900020 (7) - scopus: 2-s2.0-85127569170 (9)

11573/1616979 - 2022 - RAS mutation conversion in bevacizumab-treated metastatic colorectal cancer patients: a liquid biopsy based study
Nicolazzo, C.; Belardinilli, F.; Vestri, A.; Magri, V.; De Renzi, G.; De Meo, M.; Caponnetto, S.; Di Nicolantonio, F.; Cortesi, E.; Giannini, G.; Gazzaniga, P. - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000771452500001 (11) - scopus: 2-s2.0-85123942255 (10)



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