Dottorato in MORFOGENESI E INGEGNERIA TISSUTALE

email: maurilio.sampaolesi@uniroma1.it
telefono: +39 06 49766754
edificio: RM008
stanza: studio 13

Formazione
1997-1999 Postdoc, Dipartimento di Fisiologia Molecolare, NCVC, Suita-city, Osaka, Giappone
1997 Dottorato di Ricerca in “Fisiopatologia Cardiovascolare”, Università di Tor Vergata, Roma, Italia
1994 Esame di Stato e iscrizione all’albo Biologi, n # 044660
1991 Laurea in Scienze Biologiche, Università La Sapienza, Roma, Italia

Esperienze professionali
2021 Professore di Istologia ed Embriologia Medica, Sapienza Università di Roma, Italia
2018 Professore di Biologia delle Cellule Staminali, KU Leuven,
2011-2021Professore Associato di Anatomia Umana, Università di Pavia, Italia
2007 Direttore del Laboratorio di Cardiomiologia Traslazionale, Leuven, Belgio
2005 Ricercatore, Anatomia Umana, Università di Pavia, Italia
2000-2005 Ricercatore, Fondazione Telethon, DIBIT, Ospedale San Raffaele Milano, Italia
1999-2000 Ricercatore, Azienda Farmaceutica Dompé SpA, L'Aquila, Italia
1997 Informatore medico scientifico, Azienda Farmaceutica SIFI, Catania, Italia

Riconoscimenti
2018 Premio miglior comunicazione orale e poster - Premio Prof. Paolo Bianco IX Stem Cell Res, Milano
2011 Premio migliore presentazione, ASCR EMBO Meeting, Parigi
2008 Premio per il progetto scientifico sulla rigenerazione muscolare, FWO-Odysseus Bruxelles
2007 Premio per il miglior progetto scientifico sulle cellule staminali, Fondazione Mai, Milano
2006 Premio per il miglior team scientifico al San Raffaele Scientific Institute, Retreat, Bardolino
2000 Task Force 463/bi su “Terapia con cellule staminali per le distrofie muscolari” Telethon, Italy
1997 Premio per il miglior progetto scientifico sulla distrofia muscolare. JISTEC Osaka, Giappone

Attività didattica
2021-
ISTOLOGIA ED EMBRIOLOGIA [97903] Medicina e chirurgia "D";
HISTOLOGY AND EMBRYOLOGY [1037600] Medicine and surgery (IN LINGUA INGLESE)
HISTOLOGY AND EMBRYOLOGY [1037600] Dentistry and Dental Prosthodontics (DAL 2022/2023)
2007-
STEM CELL BIOLOGY and HOT TOPIC (IN LINGUA INGLESE), KU Leuven, Belgio
2005-2021
ANATOMIA E ISTOLOGIA [503467] LOGOPEDIA FISIOTERAPIA TECNICA DELLA RIABILITAZIONE PSICHIATRICA, TERAPIA DELLA NEURO E PSICOMOTRICITÀ DELL'ETÀ EVOLUTIVA, TERAPIA OCCUPAZIONALE
ANATOMIA E ISTOLOGIA [503467] BIOTECNOLOGIE TRIENNALE
MORFOLOGIA AVANZATA [500160] BIOTECNOLOGIE MEDICHE E FARMACEUTICHE
ANATOMIA E FISIOLOGIA UMANA [504264] BIOTECNOLOGIE (FINO AL 2017/2018)
FISIOLOGIA UMANA E ANATOMIA [502008] BIOTECNOLOGIE FINO AL 2017/2018)
CITOLOGIA E ISTOLOGIA [500321] SCIENZE BIOLOGICHE (FINO AL 2016/2017)
CITOLOGIA ED ISTOLOGIA [81533] SCIENZE BIOLOGICHE (L)(FINO AL 2016/2017)
ANATOMY 2 [501701] MEDICINA E CHIRURGIA (IN LINGUA INGLESE) (FINO AL 2014/2015)
ANATOMY [500467] MEDICINA E CHIRURGIA (IN LINGUA INGLESE) (LM)(FINO AL 2013/2014)
FISIOLOGIA UMANA E ANATOMIA [502008] BIOTECNOLOGIE (L)(FINO AL 2011/2012)
ANATOMIA UMANA [350023] BIOTECNOLOGIE (L)(FINO AL 2010/2011)

Attività scientifica
Ha ottenuto riconoscimenti internazionali per i risultati ottenuti nel settore di ricerca sulle cellule staminali e loro applicazioni terapeutiche nelle degenerazioni muscolari con supporti economici nazionali, Europei, Giapponesi ed Americani e pubblicazioni scientifiche su riviste prestigiose quali Nature, Science, Cell Stem Cell, Journal of Experimental Medicine, Journal of Clinical Investigation, Stem Cell Reports, and Nucleic Acids Res. È inoltre responsabile di un’attività di ricerca in collaborazione con l’Università di Leuven, Belgio con scambi di studenti Erasmus ed è/stato coinvolto in diversi consorzi europei, tra cui ERA4Health Joint Transnational Call, EU-INTERREG GYM e FP7 CARE-MI. È inoltre inventore (WO 2015172207 A1. PCT/BE2015/00002) per la generazione di progenitori mesodermici da cellule staminali pluripotenti umane (UK patent application #GB1408712.6). Un metodo per la produzione di cellule progenitrici mesodermiche da cellule staminali pluripotenti. Ha recentemente ottenuto un altro brevetto (WO 2019086515. PCT/EP2018/079826) sull’uso di miRNA per aumentare il differenziamento miogenico delle cellule staminali pluripotenti (UK patent application # GB1717939.1). Progetti di R & D con MONA CELL, Belgio sponsorizzato da IWT, Dompe, Biotech (Italia) Coretherapix S.L. (Spagna), mentre iTeos (Belgio), Evox Therapeutics (Regno Unito) e più recentemente con AgomAb Therapeutics NV (Belgio), sponsorizzato da VLAIO sono direttamente coinvolti in progetti in corso e si riferiscono principalmente alle tecnologie dei miRNAs/exosomi.

Finanziamenti (lista parziale)
ERA4Health Joint Transnational Call 2023: AmnioSMART: Defining the ideal human Amniotic progenitor Secretome forMulation for future cArdioprotective paRacrine Therapy. Ricerca finalizzata- RF-2019-12369703 IPSCs from Duchenne Muscular Dystrophy: perfect genetic correction by chromosome transplantation and generation of 3D cell culture for drug investigation. Sapienza Roma, Humanitas e San Raffaele (2021-2024); FWO - 3D Vascularized cardiac organoid on-chip for modeling of dystrophic and mytogenic cardiomyopathy. (2020-2024); EU INTERREG-GYM project (2020-2023); MITOX- FTBO (Fund for Translational Biomedical Research) project (2020-2023); Rondoufonds voor Duchenne Onderzoek grant, (2021); CARIPLO Foundation – Exploring the role of ghrelin peptides in sarcopenia development during aging with Turin and Novara Universities (2015-2018); FWO - Modulation of intercellular communication of mesodermal progenitors to enhance striated muscle regeneration (2016-2020); FWO - Bipotential progenitor cells to treat cardiac and skeletal muscle degeneration in a large animal model of Duchenne Muscular Dystrophy (2014-2018); Opening the future # EJJ-OPTFUT - Novel therapeutic approaches for the treatment of Muscular Dystrophies: iPSC and TALEN technologies for myogenic regeneration (2012-2017); IUAPVII-07 DevRepair– Paracrine and transcriptional control of cell differentiation in organ development and repair - (2013-2016); FWO - Epigenetic memory and miRNA therapeutic targeting in an animal model for limb girdle muscular dystrophy type 2E (2012-2015); FWO -Mesoangioblast reprogramming: potential in myogenic differentiation 180.000 € (2010-2017) -Programmafinanciering KUL PF/10/00300 -Stem Cell Program (2010-2015); GOA KUL– Growth factor signal interpretation in stem cells and the early embryo (2010-2015); EU FP7 #242038 CARE-MI – Activation of endogenous cells as an approach to regenerative medicine (2010-2014); CARIPLO Reprogramming adult stem cells- Creation of an International Research Group (2010-2014); AFM TELETHON #14616 – In vivo tracking of mesoangioblasts in dystrophin-deficient dog: methodological development (2010-2012) - PRIN-COFIN Ministry of Health, Italy. Terapia cellulare in modelli murini per la cardiomiopatia cronica ereditaria (2010-2011); IOF Hefboomproject #HB-10-044 – High content drug screening with contractile cardiac tissue 100.000€; (2009-2013) - OT #09-053 – Paracrine and transcriptional regulation of renewal and differentiation of embryonic and adult multi-potent progenitor cells in vertebrates (2009-2013); - Luban foundation – Stem cell therapy in animal model for LGMD type 2D. (2009-2011) 100.000€; salary support for PhD student (2008-2013) - Minnesota University/KULeuven Wicka Funds n. zkb8720 – Improvements in stem cell therapy for muscular dystrophies (2007-2012); FWO Odysseus Program– Molecular mechanisms of cardiomyopathy related to muscular dystrophy and stem cell therapy (2007-2012); PRIN-COFIN Ministry of Health, Italy. Osteoinduzione ed osteoconduzione in cellule staminali umane adulte mediante crescita su biomateriali, esposizione a campi magnetici e coltura in bioreattore a perfusione

Società scientifiche, attività editoriale e comitati valutativi
Membro della società Italiana di Anatomia e Istologia, European Society of Gene and cell Therapy, International Society for Stem Cell Research (ISSCR), Belgian Society for Stem Cell Research International Society for Stem Cell Research (ISSCR since2005).
Deputy Editor (2013-2017) e Associate Editor per la rivista Cardiovascular Research; Academic Editor per le riviste Scientific Reports e International Journal of Molecular Sciences (dal 2018), Frontiers Journals, Stem Cell Research Panel (dal 2012), PLOSONE (dal 2010). Scientific board: Human Gene Therapy, Cell and Developmental Biology, BAM Basic and Applied Myology. Reviewer per Nat Cell Biol, Nature Communications, Biomaterials, Cell Death and Differentiation, Cell Death & Disease, FASEB Journal, Human Gene Therapy, PLOSONE, Stem Cells, Trends in Molecular Medicine, Tissue engineering, Journal of Cell Science, Cell Transplantation.
Scientific Advisory Board REGMEDXB, Panel reviewer per ERC starting (dal 2010-) consolidator (dal 2014) e advanced grants (dal 2018). Panel member per diverse agenzie straniere che supportanto la ricerca quali Swiss National Science Foundation, Research Grants Council (RGC) of Hong Kong, Clinical and Applied Biomedical Research, Health Research Board of Ireland e Stem Cell Committee, AFM-Telethon France (dal 2012).

Seminari su invito (lista parziale)
2D-3D Stem Cell Models for Genetic Myopathies: Exploring Therapeutic Options. 10th Annual Cystinosis Workshop, Dublin, Ireland 9-10 February 2024
Stem cells for muscle repair and 3D pathophysiological models. XXXIX Congresso Società Italiana di Istochimica, Vulcano, Italy 14-16 June 2023
Harnessing novel 3D stem cell-based models to challenge dystrophic cardiomyopathy. 5th Central European Biomedical Congress, Krakow, Poland 30 May 2023
2D and 3D stem cell-based models of dystrophic cardiomyopathy.34 AICC annual meeting Orgnaoid models for human diseases. Naples, Italy 2 Dec 2022
Human iPS cell-based 3D models to reveal novel therapeutic targets for muscle degeneration. Advances in Advanced Therapy Manufacture (AMC). Amsterdam, The Netherlands, 6 October 2022.
Generate Your Muscle (GYM): Development of autologous myogenic stem cell therapy to treat myopathy. Maastricht, The Netherlands, 8 Dec 2020
Single-cell omics to decomplexify muscle stem cell heterogeneity. University of Geneve, Switzerland, 6 Feb 2020
Cell reprogramming, gene-editing and single-cell seq technologies. Unistem Milan, Italy 6 June 2019
Epigenetic memory in skeletal muscle remodelling and regeneration. St. Ann's University, Brno, Check Republic, 20 Feb 2018
Muscle stem cells and regeneration. Muscle biology & inflammation. EULAR, London, United Kingdom, 6 June 2016
Cell reprogramming and miRNA-based treatments for skeletal and cardiac muscle repair. Enrlangen University, Germany, 15 June 2015.
Novel routes towards the 'heart' of myogenesis IIIM 2014 - XI meeting Monteriggioni, Italy 2-5 October 2014
Cardiac progenitors in dystrophic stem cell niche. 7th Qianjiang International Cardiovascular Congress (QICC) Hangzhou, China, 1 August 2013
Stem cell treatment for muscular dystrophy: where we are and where we go. NCVC and Osaka University, Suita, Japan, 12 June 2012
miRNAs regulate muscle lineage switch, NIRM Amsterdam, The Netherlands, 20 September 2011
Magic-factor 1 and muscle hypertrophy. 5th Cachexia World Conference Barcellona, Spain, 5-8 December 2009
Local activation or transplantation of progenitor cells in skeletal muscle diseases (speaker & chairman). European Muscle Conference 2009 Lille, France 12th-16th September 2009
Mini-symposium on muscle stem cells and muscle development (speaker & chairman). Minneapolis, USA 15 May 2009
Cell-mediated Gene Therapy for Muscular Dystrophy: Challenger and Prospects American Society for Gene Therapy (ASGT) Boston (MA), USA May 28- June 1 2008

Capitoli di libri -Monografie e enciclopedie (lista parziale)
Sampaolesi M (2024) Netter’s Sistema muscoloscheletrico. Anatomia clinica capitoli 6 e 7. ISBN 978-88-299-3444-7
Giarratana, N., Conti, F., Rinvenuti, L., Ronzoni, F., Sampaolesi, M. (2023). State of the Art Procedures for the Isolation and Characterization of Mesoangioblasts. Chapt. 8, (99–115). In: Asakura, A. (eds) Skeletal Muscle Stem Cells. Methods in Molecular Biology, vol 2640. Springer. ISBN: 978-1-0716-3035-8. doi: 10.1007/978-1-0716-3036-5_8
Yedigaryan, L., Sampaolesi, M. (2022). Skeletal Muscle–Extricated Extracellular Vesicles: Facilitators of Repair and Regeneration. In: Haider, K.H. (eds) Handbook of Stem Cell Therapy. Springer, Singapore. https://doi.org/10.1007/978-981-16-6016-0_49-1.
Breuls N, Giarratana N, Yedigaryan L, Sampaolesi M. (2022). Epigenetic modifications in induced pluripotent stem cells to boost myogenic commitment. Chapter 9 (197-223)- Editor(s): Alexander Birbrair, In Advances in Stem Cell Biology, Current Topics in iPSCs Technology, Academic Press, Volume 17, 2022, , ISBN 9780323998925, https://doi.org/10.1016/B978-0-323-99892-5.00019-0.
Giacomazzi, G., Giovannelli, G., Rotini, A., Costamagna, D., Quattrocelli, M., Sampaolesi, M. (2021). Isolation of Mammalian Mesoangioblasts: A Subset of Pericytes with Myogenic Potential. In: Pericytes, (155-167). (Methods in Molecular Biology, 2235). Springer. ISBN: 978-1-0716-1058-9. doi: 10.1007/978-1-0716-1056-5_11
Pozzo, E., Chai, Y.C., Sampaolesi, M. (2020). Comprehensive Overview of Non-coding RNAs in Cardiac Development. In: Xiao, J. (eds) Non-coding RNAs in Cardiovascular Diseases. Advances in Experimental Medicine and Biology, vol 1229. Springer, Singapore. https://doi.org/10.1007/978-981-15-1671-9_11
Sampaolesi, M., Quattrocelli, M., Pozzo, E. (2020). Stem cells in muscle development, diseases and regeneration. In: Stem Cells, Chapt. 7, (93-118). Societa Editrice Esculapio. ISBN: 8893851717.
Duelen, R., Corvelyn, M., Tortorella, I., Leonardi, L., Chai, Y.C., Sampaolesi, M. (2019). Medicinal Biotechnology for Disease Modeling, Clinical Therapy, and Drug Discovery and Development. In: F. Matei, D. Zirra (Eds.), Introduction to Biotech Entrepreneurship: From Idea to Business., Chapt. 5, (89-128). Springer Nature Switzerland AG. ISBN: 978-3-030-22140-9. doi: 10.1007/978-3-030-22141-6_5
Martínez-Sarrà, E., Montori, S., Gil-Recio, C., Núñez-Toldrà, R., Carrio Bertran, N., Al Madhoun, A., Sampaolesi, M., Atari, M. (2018). Dental pulp stem cells promote wound healing and muscle regeneration. In: Stem Cell Genetics for Biomedical Research: Past, Present, and Future, (221-240). ISBN: 9783319906942. doi: 10.1007/978-3-319-90695-9_10
Duelen, R., Costamagna, D., Sampaolesi, M. (2017). Stem cell therapy in muscle degeneration. In: The Plasticity of Skeletal Muscle: From Molecular Mechanism to Clinical Applications, (55-91). ISBN: 9789811032912. doi: 10.1007/978-981-10-3292-9_3 Open Access
Camps, J., Pozzo, E., Pulinckx, T., Duelen, R., Sampaolesi, M. (2017). Advanced Treatments and Emerging Therapies for Dystrophin- Deficient Cardiomyopathies. In: K. Kirali (Eds.), Cardiomyopathies - Types and Treatments, Chapt. 15, (289-311). InTech. ISBN: 978-953-51-3040-6. Open Access
Sampaolesi M. Cellule Staminali. IX Appendice. Treccani encyclopaedia 2016: pp 579-582
Berardi, E., Sampaolesi, M. (2015). Novel Therapeutic Approaches for Skeletal Muscle Dystrophies. In: Intech (Eds.), Muscle Cell and Tissue, Chapt. 14, (394-412). Intech. ISBN: 978-953-51-2156-5.
Tedesco, F.S., Sampaolesi, M., Cossu, G. (2013). Stem Cells for the Treatment of Muscular Dystrophy. In: Essentials of Stem Cell Biology: Third Edition, (529-542). ISBN: 9780124095038. doi: 10.1016/B978-0-12-409503-8.00036-6
Bagnara, G.P., Alviano, F., Baricordi, O.R., Berardi, E., Bonsi, L., Calzà, L., Costa, R., Fernandez, M., Giardino, L., Grossi, A., Lanza, F., Lanzoni, G., Paradisi, M., Pasquinelli, G., Quattrocelli, M., Rizzo, R., Sampaolesi, M., Sivilia, S., Ventura, C. (2013). Cellule Staminali e sistema muscolare. In: CELLULE STAMINALI, Chapt. 7, (73-95). Società Editrice Esculapio. ISBN: 9788874886296.
Tedesco, S., Sampaolesi, M., Cossu, G. (2012). Stem cells for the Treatment of Muscular Dystrophy. In: R. Lanza (Eds.), Handbook of Stem Cells, Chapt. 56, (641-651). (2). Elsevier. ISBN: 9780123859426.
Quattrocelli, M., Palazzolo, G., Perini, I., Crippa, S., Cassano, M., Sampaolesi, M. (2012). Mouse and Human Mesoangioblasts: isolation and characterization. In: J. DiMario (Eds.), Methods in Molecular Biology, (65-76). (Methods and protocols, 798). Humana Press. ISBN: 9781617793431.
Sampaolesi, M. (2010). Stem Cells. In: XXI Secolo, Il corpo e la mente, (237-246). Treccani encyclopedia 2010. ISBN: 9788809771482.
Sampaolesi, M., Cossu, G. (2009). Stem cells for the treatment of Muscular dystrophy: therapeutic perspectives. In: R. Lanza (Eds.), Stem cell biology, Chapt. 60, (543-550). Elsevier. ISBN: 978-0-12-374729-7.
Sampaolesi, M., De Angelis, M., Cossu, G. (2006). Stem cells for the treatment of Muscular Dystrophy: more than a wishful thinking? In: R. Lanza (Eds.), Essentials of Stem Cell Biology, Chapt. 58, (431-437). Elsevier. eBook ISBN: 9780080456553
Sampaolesi, M., De Angelis, M., Cossu, G. (2004). Stem cells for the treatment of Muscular Dystrophy: more than a wishful thinking? In: R. Lanza (Eds.), Handbook of Stem Cells, Chapt. 65, (721-730). Elsevier. eBook ISBN: 9780080533735

Pubblicazioni (lista parziale)
(https://orcid.org/0000-0002-2422-3757; Researcher ID: H-6509-2013; H-index: 50 (Google Scholar, i10-index: 125, >13500 citazioni; H-index: 43 (Scopus); >170 ms in PubMed)
1. Sampaolesi M, Janssens S, Duelen R. Duchenne cardiomyopathy: targeting ROS and NOX4 as a promising therapeutic strategy. Expert Opin Ther Targets. 2023 27(2):91-95. (recent IF: 5.8)
2. Vervliet T, Duelen R, Pradhan A, La Rovere R, Roderick HL, Sampaolesi M. Cardiomyocyte differentiation from human induced pluripotent stem cells is delayed following knockout of Bcl-2. J Cell Sci. 2023 136(2): jcs 260216. (recent IF: 5.285)
3. Yedigaryan L, Martínez-Sarrà E, Giacomazzi G, Giarratana N, van der Veer BK, Rotini A, Querceto S, Grosemans H, Cortés-Calabuig Á, Salucci S, Battistelli M, Falcieri E, Gijsbers R, Quattrocelli M, Peng Koh K, De Waele L, Buyse GM, Derua R, Sampaolesi M. Extracellular vesicle-derived miRNAs improve stem cell-based therapeutic approaches in muscle wasting conditions. Front Immunol. 2022 13:977617 (recent IF: 8.787)
4. Marini V, Marino F, Aliberti F, Giarratana N, Pozzo E, Duelen R, Cortés Calabuig Á, La Rovere R, Vervliet T, Torella D, Bultynck G, Sampaolesi M*, Chai YC*. Long-term culture of patient-derived cardiac organoids recapitulated Duchenne muscular dystrophy cardiomyopathy and disease progression. Front Cell Dev Biol. 2022 10:878311 (recent IF: 6.684) *equally contributors
5. Duelen R, Costamagna D, Gilbert G, Waele L, Goemans N, Desloovere K, Verfaillie CM, Sipido KR, Buyse GM, Sampaolesi M. Human iPSC model reveals a central role for NOX4 and oxidative stress in Duchenne cardiomyopathy. Stem Cell Reports. 2022 17(2):352 (recent IF: 7.765)
6. Breuls N, Giarratana N, Yedigaryan L, Garrido GM, Carai P, Heymans S, Ranga A, Deroose C, Sampaolesi M. Valproic acid stimulates myogenesis in pluripotent stem cell-derived mesodermal progenitors in a NOTCH-dependent manner. Cell Death Dis. 2021 12(7):677. (IF: 9.696)
7. Machado L, Geara P, Camps J, Dos Santos M, Teixeira-Clerc F, Van Herck J, Varet H, Legendre R, Pawlotsky JM, Sampaolesi M, Voet T, Maire P, Relaix F, Mourikis P. Tissue damage induces a conserved stress response that initiates quiescent muscle stem cell activation. Cell Stem Cell. 2021 28(6):1125-1135.e7. (IF: 25.269)
8. Costamagna D, Duelen R, Penna F, Neumann D, Costelli P, Sampaolesi M. Interleukin-4 administration improves muscle function, adult myogenesis, and lifespan of colon carcinoma-bearing mice. J Cachexia Sarcopenia Muscle. 2020 11(3):783-801, (IF: 12.910)
9. Giarratana N, Conti F, La Rovere R, Gijsbers R, Carai P, Duelen R, Vervliet T, Bultynck G, Ronzoni F, Piciotti R, Costamagna D, Fulle S, Barravecchia I, Angeloni D, Torrente Y, Sampaolesi M. MICAL2 is essential for myogenic lineage commitment. Cell Death Dis. 2020 11(8):654. (IF: 8.469)
10. Camps J, Breuls N, Sifrim A, Giarratana N, Corvelyn M, Danti L, Grosemans H, Vanuytven S, Thiry I, Belicchi M, Meregalli M, Platko K, MacDonald ME, Austin RC, Gijsbers R, Cossu G, Torrente Y, Voet T, Sampaolesi M. Interstitial Cell Remodeling Promotes Aberrant Adipogenesis in Dystrophic Muscles. Cell Rep. 2020 31(5): 107597 (IF: 9.423)
11. Balli M, Vitali F, Janiszewski A, Caluwé E, Cortés-Calabuig A, Carpentier S, Duelen R, Ronzoni F, Marcelis L, Bosisio FM, Bellazzi R, Luttun A, De Angelis MGC, Ceccarelli G, Lluis F, Sampaolesi M. Autologous micrograft accelerates endogenous wound healing response through ERK-induced cell migration. Cell Death Differ. 2020 27(5): 1520-1538 (IF: 15.828)
12. Rotini A, Martínez-Sarrà E, Duelen R, Costamagna D, Di Filippo ES, Giacomazzi G, Grosemans H, Fulle S, and Sampaolesi M. Aging affects the in vivo regenerative potential of human mesoangioblasts. Aging Cell. 2018 17(2) (IF: 7.346)
13. Giacomazzi G, Holvoet B, Trenson S, Caluwé E, Kravic B, Grosemans H, Cortés-Calabuig Á, Deroose CM, Huylebroeck D, Hashemolhosseini S, Janssens S, McNally E, Quattrocelli M, Sampaolesi M. MicroRNAs promote skeletal muscle differentiation of mesodermal iPSC-derived progenitors. Nat Commun. 2017 8(1): 1249 (IF: 12.353)
14. Sacchetti B, Funari A, Remoli C, Giannicola G, Kogler G, Liedtke S, Cossu G, Serafini M, Sampaolesi M, Tagliafico E, Tenedini E, Saggio I, Robey PG, Riminucci M, Bianco P. No Identical "Mesenchymal Stem Cells" at Different Times and Sites: Human Committed Progenitors of Distinct Origin and Differentiation Potential Are Incorporated as Adventitial Cells in Microvessels. Stem Cell Reports 2016 6(6):897-913. (IF: 7.338).
15. Quattrocelli M, Swinnen M, Giacomazzi G, Camps J, Barthélemy I, Ceccarelli G, Caluwé E, Grosemans H, Thorrez L, Pelizzo G, Muijtjens M, Verfaillie CM, Blot S, Janssens S, Sampaolesi M. Mesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscle. J Clin Invest. 2015, 125(12): 4463-82 (IF: 12.575)
16. Tedesco FS, Gerli MF, Perani L, Benedetti S, Ungaro F, Cassano M, Antonini S, Tagliafico E, Artusi V, Longa E, Tonlorenzi R, Ragazzi M, Calderazzi G, Hoshiya H, Cappellari O, Mora M, Schoser B, Schneiderat P, Oshimura M, Bottinelli R, Sampaolesi M, Torrente Y, Broccoli V, Cossu G. Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy. Sci Transl Med 2012 4(140): 140ra89. IF= 10.757
17. Cassano M, Quattrocelli M, Dellavalle A, Salvade A, Ronzoni F, Cossu G and Sampaolesi M. Alpha sarcoglycan is required for FGF dependent myogenic progenitor cell proliferation in vitro and in vivo. Development 2011 138(20): 4523-33 IF= 6,596
18. Sampaolesi M, Blot S, Bottinelli R, and Cossu G. Brief Communication Arising in Replying to Bretag AH Nature 2007 450: E23-25 (IF: 28.751)
19. Sampaolesi M, Blot S, D'Antona G, Granger N, Tonlorenzi R, Innocenzi A, Mognol P, Thibaud JL, Galvez BG, Barthélémy I, Perani L, Mantero S, Guttinger M, Pansarasa O, Rinaldi C, Cusella De Angelis MG, Torrente Y, Bordignon C, Bottinelli R, Cossu G. Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs. Nature 2006 444(7119): 574-9 (IF: 26.681)
20. Sampaolesi M, Torrente Y, Innocenzi A, Tonlorenzi R, D'Antona G, Pellegrino MA, Barresi R, Bresolin N, De Angelis MG, Campbell KP, Bottinelli R, Cossu G. Cell therapy of alpha-sarcoglycan null dystrophic mice through intra-arterial delivery of mesoangioblasts. Science 2003 301(5632): 487-92 (IF: 29.781)