11573/1725469 - 2024 -
Clinical assessment and genetic testing for hereditary polyposis syndromes in an Italian cohort of patients with colorectal polyps Fasano, C.; Cariola, F.; Forte, G.; Buonadonna, A. L.; Sanese, P.; Manghisi, A.; Lepore Signorile, M.; De Marco, K.; Grossi, V.; Disciglio, V.; Simone, C - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: (0) - scopus: (0)
11573/1725434 - 2024 -
In Silico Deciphering of the Potential Impact of Variants of Uncertain Significance in Hereditary Colorectal Cancer Syndromes Fasano, C.; Lepore Signorile, M.; De Marco, K.; Forte, G.; Disciglio, V.; Sanese, P.; Grossi, V.; Simone, C. - 01g Articolo di rassegna (Review)
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: (0) - scopus: (0)
11573/1725431 - 2024 -
Clinical and Molecular Characterization of SMAD4 Splicing Variants in Patients with Juvenile Polyposis Syndrome Forte, G.; Buonadonna, A. L.; Fasano, C.; Sanese, P.; Cariola, F.; Manghisi, A.; Guglielmi, A. F.; Lepore Signorile, M.; De Marco, K.; Grossi, V.; Disciglio, V.; Simone, C. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: (0) - scopus: (0)
11573/1725463 - 2024 -
Exploring the Relationship of rs2802292 with Diabetes and NAFLD in a Southern Italian Cohort-Nutrihep Study Forte, G.; Donghia, R.; Lepore Signorile, M.; Tatoli, R.; Bonfiglio, C.; Losito, F.; De Marco, K.; Manghisi, A.; Guglielmi, F. A.; Disciglio, V.; Fasano, C.; Sanese, P.; Cariola, F.; Buonadonna, A. L.; Grossi, V.; Giannelli, G.; Simone, C - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: (0) - scopus: (0)
11573/1725470 - 2024 -
The novel SMYD3 inhibitor EM127 impairs DNA repair response to chemotherapy-induced DNA damage and reverses cancer chemoresistance Sanese, P.; De Marco, K.; Lepore Signorile, M.; La Rocca, F.; Forte, G.; Latrofa, M.; Fasano, C.; Disciglio, V.; Di Nicola, E.; Pantaleo, A.; Bianco, G.; Spilotro, V.; Ferroni, C.; Tubertini, M.; Labarile, N.; De Marinis, L.; Armentano, R.; Gigante, G.; Lantone, V.; Lantone, G.; Naldi, M.; Bartolini, M.; Varchi, G.; Del Rio, A.; Grossi, V.; Simone, C - 01a Articolo in rivista
rivista: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. - - issn: 1756-9966 - wos: (0) - scopus: (0)
11573/1725467 - 2024 -
Methyltransferases in cancer drug resistance: unlocking the potential of targeting SMYD3 to sensitize cancer cells Sanese, P.; Fasano, C.; Lepore Signorile, M.; De Marco, K.; Forte, G.; Disciglio, V.; Grossi, V.; Simone, C - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Amsterdam: Elsevier) pp. - - issn: 1879-260X - wos: (0) - scopus: (0)
11573/1696731 - 2023 -
SMYD3 Modulates the HGF/MET Signaling Pathway in Gastric Cancer De Marco, Katia; Lepore Signorile, Martina; Di Nicola, Elisabetta; Sanese, Paola; Fasano, Candida; Forte, Giovanna; Disciglio, Vittoria; Pantaleo, Antonino; Varchi, Greta; Del Rio, Alberto; Grossi, Valentina; Simone, Cristiano - 01a Articolo in rivista
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:001092458900001 (2) - scopus: 2-s2.0-85175039859 (2)
11573/1725428 - 2023 -
Classic galactosemia: clinical and computational characterization of a novel GALT missense variant (p.A303D) and a literature review -Forte, G.; Buonadonna, A. L.; Pantaleo, A.; Fasano, C.; Capodiferro, D.; Grossi, V.; Sanese, P.; Cariola, F.; De Marco, K.; Lepore Signorile, M.; Manghisi, A.; Guglielmi, A. F.; Simonetti, S.; Laforgia, N.; Disciglio, V.; Simone, C - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: (0) - scopus: (0)
11573/1696726 - 2023 -
Uncoupling p38α nuclear and cytoplasmic functions and identification of two p38α phosphorylation sites on β-catenin: implications for the Wnt signaling pathway in CRC models Lepore Signorile, Martina; Fasano, Candida; Forte, Giovanna; De Marco, Katia; Sanese, Paola; Disciglio, Vittoria; Di Nicola, Elisabetta; Pantaleo, Antonino; Simone, Cristiano; Grossi, Valentina - 01a Articolo in rivista
rivista: CELL & BIOSCIENCE (London : BioMed Central) pp. 223- - issn: 2045-3701 - wos: WOS:001112736500004 (3) - scopus: 2-s2.0-85178190065 (3)
11573/1696727 - 2023 -
SMYD3 Modulates AMPK-mTOR Signaling Balance in Cancer Cell Response to DNA Damage Lepore Signorile, Martina; Sanese, Paola; Di Nicola, Elisabetta; Fasano, Candida; Forte, Giovanna; De Marco, Katia; Disciglio, Vittoria; Latrofa, Marialaura; Pantaleo, Antonino; Varchi, Greta; Del Rio, Alberto; Grossi, Valentina; Simone, Cristiano - 01a Articolo in rivista
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:001108133600001 (5) - scopus: 2-s2.0-85178357780 (6)
11573/1725422 - 2023 -
Understanding the genetic landscape of pancreatic ductal adenocarcinoma to support personalized medicine: A systematic review Pantaleo, A.; Forte, G.; Fasano, C.; Lepore Signorile, M.; Sanese, P.; De Marco, K.; Di Nicola, E.; Latrofa, M.; Grossi, V.; Disciglio, V.; Simone, C - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: (0) - scopus: (0)
11573/1696729 - 2023 -
Tumor Testing and Genetic Analysis to Identify Lynch Syndrome Patients in an Italian Colorectal Cancer Cohort Pantaleo, Antonino; Forte, Giovanna; Cariola, Filomena; Valentini, Anna Maria; Fasano, Candida; Sanese, Paola; Grossi, Valentina; Buonadonna, Antonia Lucia; De Marco, Katia; Lepore Signorile, Martina; Guglielmi, Anna Filomena; Manghisi, Andrea; Gigante, Gianluigi; Armentano, Raffaele; Disciglio, Vittoria; Simone, Cristiano - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:001092283000001 (5) - scopus: 2-s2.0-85175088817 (5)
11573/1656400 - 2022 -
Identification and Somatic Characterization of the Germline PTEN Promoter Variant rs34149102 in a Family with Gastrointestinal and Breast Tumors Disciglio, Vittoria; Sanese, Paola; Fasano, Candida; Lotesoriere, Claudio; Valentini, Anna Maria; Forte, Giovanna; Lepore Signorile, Martina; De Marco, Katia; Grossi, Valentina; Lolli, Ivan; Cariola, Filomena; Simone, Cristiano - 01a Articolo in rivista
rivista: GENES (Basel : Molecular Diversity Preservation International) pp. 644- - issn: 2073-4425 - wos: WOS:000786837400001 (4) - scopus: 2-s2.0-85128694925 (4)
11573/1656394 - 2022 -
Identifying novel SMYD3 interactors on the trail of cancer hallmarks Fasano, Candida; Lepore Signorile, Martina; De Marco, Katia; Forte, Giovanna; Sanese, Paola; Grossi, Valentina; Simone, Cristiano - 01a Articolo in rivista
rivista: COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (Göteborg : Chalmers University of Technology, 2011-) pp. - - issn: 2001-0370 - wos: WOS:000793825600013 (9) - scopus: 2-s2.0-85129337682 (9)
11573/1657012 - 2022 -
c-MYC Protein Stability Is Sustained by MAPKs in Colorectal Cancer Lepore Signorile, Martina; Grossi, Valentina; Fasano, Candida; Forte, Giovanna; Disciglio, Vittoria; Sanese, Paola; De Marco, Katia; La Rocca, Francesca; Armentano, Raffaele; Valentini, Anna Maria; Giannelli, Gianluigi; Simone, Cristiano - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. 4840- - issn: 2072-6694 - wos: WOS:000866673300001 (7) - scopus: 2-s2.0-85139963157 (7)
11573/1656396 - 2021 -
APC Splicing Mutations Leading to In-Frame Exon 12 or Exon
13 Skipping Are Rare Events in FAP Pathogenesis and Define
the Clinical Outcome Disciglio, Vittoria; Forte, Giovanna; Fasano, Candida; Sanese, Paola; Lepore Signorile, Martina; De Marco, Katia; Grossi, Valentina; Cariola, Filomena; Simone, Cristiano - 01a Articolo in rivista
rivista: GENES (Basel : Molecular Diversity Preservation International) pp. - - issn: 2073-4425 - wos: WOS:000633640300001 (4) - scopus: 2-s2.0-85102290300 (3)
11573/1613271 - 2021 -
Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoids Lepore Signorile, M.; Grossi, V.; Di Franco, S.; Forte, G.; Disciglio, V.; Fasano, C.; Sanese, P.; De Marco, K.; Susca, F. C.; Mangiapane, L. R.; Nicotra, A.; Di Carlo, G.; Dituri, F.; Giannelli, G.; Ingravallo, G.; Canettieri, G.; Stassi, G.; Simone, C. - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000635208800001 (13) - scopus: 2-s2.0-85103476406 (13)
11573/1336752 - 2019 -
Gastric polyposis and desmoid tumors as a new familial adenomatous polyposis clinical variant associated with APC mutation at the extreme 3’-end Disciglio, V; Fasano, C; Cariola, F; Forte, G; Grossi, V; Sanese, P; Lepore Signorile, M; Resta, N; Lotesoriere, C; Stella, A; Lolli, I; Simone, C - 01a Articolo in rivista
rivista: JOURNAL OF MEDICAL GENETICS (BMJ / British Medical Journal Publishing Group:PO Box 299, London WC1H 9TD United Kingdom:011 44 20 73836270, EMAIL: subscriptions@bmjgroup.com, INTERNET: http://www.bmjpg.com/bmj, Fax: 011 44 20 73836402) pp. 1-5 - issn: 0022-2593 - wos: WOS:000531369500010 (14) - scopus: 2-s2.0-85073110152 (14)
11573/1336757 - 2019 -
FOXO3a from the nucleus to the mitochondria: a round trip in cellular stress response Fasano, C; Disciglio, V; Bertora, S; Lepore Signorile, M; Simone, C - 01g Articolo di rassegna (Review)
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000489103800169 (149) - scopus: 2-s2.0-85085904627 (152)
11573/1336745 - 2019 -
Chasing the FOXO3: insights into its new mitochondrial lair in colorectal cancer landscape Grossi, V; Fasano, C; Celestini, V; Lepore Signorile, M; Sanese, P; Simone, C - 01g Articolo di rassegna (Review)
rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000468550200144 (15) - scopus: 2-s2.0-85064468386 (18)
11573/1174873 - 2018 -
Inversion Variants in Human and Primate Genomes Catacchio, C.; Maggiolini, F. A. M.; D’Addabbo, P.; Bitonto, M.; Capozzi, O.; Lepore Signorile, M.; Miroballo, M.; Archidiacono, N.; Ventura, M.; Eichler, E. E.; Antonacci., F. - 01a Articolo in rivista
rivista: GENOME RESEARCH (Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press) pp. - - issn: 1549-5469 - wos: WOS:000436084800015 (29) - scopus: 2-s2.0-85048132728 (30)
11573/1174869 - 2018 -
The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer. Grossi, V; Forte, G; Sanese, P; Peserico, A; Tezil, T; Lepore Signorile, M; Fasano, C; Bagnulo, R; Loconte, Dc; Susca, Fc; Resta N And Simone, C. - 01a Articolo in rivista
rivista: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485
Editore precedente:
Information Retrieval ltd., London) pp. 5587-5600 - issn: 0305-1048 - wos: WOS:000438362400022 (51) - scopus: 2-s2.0-85050581868 (54)
11573/1174880 - 2018 -
The MAPK/C-Myc Axis in CRC: new pathogenic mechanisms and therapeutic approaches Lepore Signorile, M; Grossi, V; Sanese, P; Celestini, V; Fasano, C; Forte, G; Russo, L; Disciglio, V; Simone, C - 04f Poster
congresso: European Association for Cancer Research (Amsterdam; Netherlands)
libro: 25TH biennal EACR - ()
11573/1174875 - 2018 -
Manipulating MAPK/c-Myc axis to overcome chemoresistance in CRC Lepore Signorile, Martina; Grossi1, Valentina; Sanese1, Paola; Celestini1, Valentina; Fasano3, Candida; Forte3, Giovanna; Disciglio3, Vittoria; Simone1, Cristiano; 3, - 04f Poster
congresso: 30th Pezcoller Symposium (Trento, Italy)
libro: 30th Pezcoller Symposium - ()
11573/1336734 - 2018 -
Integrated multi-omics characterization reveals a distintive metabolic signature and the role of NDUFAL4L2 in promoting angiogenesis, chemoresistance, and mitochondrial dysfunction in clear cell renal cell carcinoma Lucarelli, G; Rutigliano, M; Sallustio, F; Ribatti, D; Giglio, A; Lepore Signorile, M; Grossi, V; Sanese, P; Napoli, A; Maiorano, E; Bianchi, C; Perego, Ra; Ferro, M; Ranieri, E; Serino, G; Ditonno, P; Simone, C; Battaglia, M. - 01a Articolo in rivista
rivista: AGING (Impact Journals LLC) pp. 3957-3985 - issn: 1945-4589 - wos: WOS:000454633200033 (163) - scopus: 2-s2.0-85059323917 (164)
11573/1174865 - 2018 -
Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy Valentina, Celestini; Tugsan, Tezil; Luciana, Russo; Candida, Fasano; Paola, Sanese; Giovanna, Forte; Alessia, Peserico; Lepore Signorile, Martina; Giovanna, Longo; Domenico De, Rasmo; Anna, Signorile; Raffaella Maria, Gadaleta; Natasha, Scialpi; Mineko, Terao; Enrico, Garattini; Tiziana, Cocco; Gaetano, Villani; Antonio, Moschetta; Valentina Grossi And Cristiano, Simone. - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000427410000012 (38) - scopus: 2-s2.0-85042092861 (40)