MARIA PIA FELLI

Professore associato

email: mariapia.felli@uniroma1.it
telefono: 00 39 06 49255673
edificio: palazzina B/building B
stanza: stanza 411/room 411

BREVE CURRICULUM VITAE

QUALIFICA ATTUALE (con SSD): Professore Associato del settore-scientifico disciplinare Med06/A2
DIPARTIMENTO: Medicina Sperimentale, Università degli Studi La Sapienza-Roma

ALTRI INCARICHI:
2019-oggi: Responsabile di un accordo interuniversitario internazionale Erasmus+ Bilateral Agreement
2024-2025: Tutor V e VI annualità del Gruppo di Lavoro Qualità e Innovazione della Didattica (QUID)

FORMAZIONE E CARRIERA
2014-2025: Abilitazione Scientifica Nazionale (ASN) alle funzioni di professore universitario di Prima Fascia nel settore concorsuale 06/N1(09-06-2014 al 09-06-2025).
2001-oggi: Professore Associato, Dipartimento di Medicina Sperimentale, Università La Sapienza-Roma
1995-2001: Ricercatore, SSD-F04A, Dipartimento di Medicina Sperimentale,Università degli Studi di L’Aquila, L’Aquila
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1994-95: Post-doc presso il Dipartimento di Medicina Sperimentale della Facoltà di Medicina e Chirurgia dell'Università degli Studi di L'Aquila
1993: Ph.D in Biotecnologia e Biometria, Università degli Studi di L’Aquila, L’Aquila
26-06-1984: laurea in Scienze Biologiche, Università degli Studi La Sapienza – Roma

PRINCIPALI LINEE DI RICERCA
1. Regolazione genica da aprte degli steroidi in cellule umane tumorali. Recettori dei glucocorticoidi (GR) e dell’acido retinoico (RAR).
2.Studio dei meccanismi molecolari innescati dall’attivazione di Notch nel differenziamento delle cellule T e nella leucemia acuta.
3. Identificazione di markers inmplicati nella progressione della leucemia linfoblastica acuta (LLA) di tipo T indotta da Notch. Ruolo dei recettori delle chemochine.
4. Studio dei microRNA implicati nei programmi differenziativi delle cellule T, e nello sviluppo e progressione della LLA di tipo T.

COLLABORAZIONI
Prof.ssa Maria Josè Diaz-Guerra e Prof. Javier Garcia-Ramirez, Università di Castilla-La Mancha, Campus de Albacete, Albacete, Spagna.
Prof. ssa M.L. Toribio, Universidad Autonoma de Madrid, Campus Cantoblanco, Madrid, Spagna
Prof.ssa Sara Gonzalez-Garcia Universidad Complutense de Madrid, Madrid, Spagna,
Prof.ssa Lisa Minter, College of Natural Sciences University of Massachusetts, Amherst, MA, U.S.A

CINQUE PUBBLICAZIONI SELEZIONATE
-Notch3 and canonical NF-kappaB signaling pathways cooperatively regulate Foxp3 transcription.
Barbarulo A, Grazioli P, Campese AF, Bellavia D, Di Mario G, Pelullo M, Ciuffetta A, Colantoni S, Vacca A, Frati L, Gulino A, Felli MP, Screpanti I. J Immunol. 2011 Jun 1;186(11):6199-206. doi: 10.4049/jimmunol.1002136. Epub 2011 Apr 20. PMID: 21508258
-Intrathymic Notch3 and CXCR4 combinatorial interplay facilitates T-cell leukemia propagation.
Ferrandino F, Bernardini G, Tsaouli G, Grazioli P, Campese AF, Noce C, Ciuffetta A, Vacca A, Besharat ZM, Bellavia D, Screpanti I, Felli MP. Oncogene. 2018 Dec;37(49):6285-6298. doi: 10.1038/s41388-018-0401-2. Epub 2018 Jul 23. PMID: 30038265.
-Thymic-Epithelial-Cell-Dependent Microenvironment Influences Proliferation and Apoptosis of Leukemic Cells.
Patel SK, Zhdanovskaya N, Sergio I, Cardinale A, Rosichini M, Varricchio C, Pace E, Capalbo C, Locatelli F, Macone A, Velardi E, Palermo R, Felli MP. Int J Mol Sci. 2024 Jan 24;25(3):1412. doi: 10.3390/ijms25031412. PMID: 38338689
-Notch3-regulated microRNAs impair CXCR4-dependent maturation of thymocytes allowing maintenance and progression of T-ALL.
Sergio I, Varricchio C, Patel SK, Del Gaizo M, Russo E, Orlando A, Peruzzi G, Ferrandino F, Tsaouli G, Coni S, Peluso D, Besharat ZM, Campolo F, Venneri MA, Del Bufalo D, Lai S, Indraccolo S, Minuzzo S, La Starza R, Bernardini G, Screpanti I, Campese AF, Felli MP. Oncogene. 2024 Aug;43(34):2535-2547. doi: 10.1038/s41388-024-03079-0. Epub 2024 Jun 21. PMID: 38907003
-Notch Inhibitors and BH3 Mimetics in T-Cell Acute Lymphoblastic Leukemia.
Sergio I, Varricchio C, Squillante F, Cantale Aeo NM, Campese AF, Felli MP. Int J Mol Sci. 2024 Nov 29;25(23):12839. doi: 10.3390/ijms252312839. PMID: 39684550

Produzione scientifica

11573/1721694 - 2024 - The NF-κB1/p50 subunit influences the Notch/IL-6-driven expansion of Myeloid-Derived Suppressor Cells in murine T-Cell Acute Lymphoblastic Leukemia

Abdollahzadeh, B.; Cantale Aeo, N. M.; Giordano, N.; Orlando, A.; Basciani, M.; Peruzzi, G.; Grazioli, P.; Screpanti, I.; Felli, M. P.; Campese, A. F. - 01a Articolo in rivista

rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-15 - issn: 1422-0067 - wos: WOS:001323137700001 (0) - scopus: 2-s2.0-85205235833 (0)

11573/1715902 - 2024 - MicroRNA and renal fibrosis in autosomal dominant polycystic kidney disease: a longitudinal study

Lai, Silvia; Mastroluca, Daniela; Perrotta, Adolfo Marco; Muscaritoli, Maurizio; Lucciola, Sara; Felli, Maria Pia; Izzo, Paolo; Rotondi, Silverio; Izzo, Sara; Tartaglione, Lida; Belli, Roberta; Ramaccini, Cesarina; Izzo, Luciano; De Intinis, Claudia; Panebianco, Valeria; Mazzaferro, Sandro - 01a Articolo in rivista

rivista: JN. JOURNAL OF NEPHROLOGY (Springer Nature Milano: Wichtig.) pp. - - issn: 1724-6059 - wos: WOS:001263307000001 (0) - scopus: 2-s2.0-85197490766 (0)

11573/1700554 - 2024 - Thymic-epithelial-cell-dependent microenvironment influences proliferation and apoptosis of leukemic cells

Patel, Sandesh Kumar; Zhdanovskaya, Nadezda; Sergio, Ilaria; Cardinale, Antonella; Rosichini, Marco; Varricchio, Claudia; Pace, Eleonora; Capalbo, Carlo; Locatelli, Franco; Macone, Alberto; Velardi, Enrico; Palermo, Rocco; Felli, Maria Pia - 01a Articolo in rivista

rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-13 - issn: 1422-0067 - wos: WOS:001160399400001 (0) - scopus: 2-s2.0-85184670334 (0)

11573/1712118 - 2024 - Notch3-regulated microRNAs impair CXCR4-dependent maturation of thymocytes allowing maintenance and progression of T-ALL

Sergio, Ilaria; Varricchio, Claudia; Patel, Sandesh Kumar; Del Gaizo, Martina; Russo, Eleonora; Orlando, Andrea; Peruzzi, Giovanna; Ferrandino, Francesca; Tsaouli, Georgia; Coni, Sonia; Peluso, Daniele; Besharat, Zein Mersini; Campolo, Federica; Venneri, Mary Anna; Del Bufalo, Donatella; Lai, Silvia; Indraccolo, Stefano; Minuzzo, Sonia; La Starza, Roberta; Bernardini, Giovanni; Screpanti, Isabella; Campese, Antonio Francesco; Felli, Maria Pia - 01a Articolo in rivista

rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 2535-2547 - issn: 0950-9232 - wos: WOS:001251528300001 (3) - scopus: 2-s2.0-85196519292 (2)

11573/1729233 - 2024 - Notch inhibitors and BH3 mimetics in T-cell acute lymphoblastic leukemia

Sergio, Ilaria; Varricchio, Claudia; Squillante, Federica; Cantale Aeo, Noemi Martina; Campese, Antonio Francesco; Felli, Maria Pia - 01g Articolo di rassegna (Review)

rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-20 - issn: 1422-0067 - wos: WOS:001377194600001 (0) - scopus: 2-s2.0-85211824937 (0)

11573/1686078 - 2023 - Bcl-2 family inhibitors sensitize human cancer models to therapy

Valentini, Elisabetta; Di Martile, Marta; Brignone, Matteo; Di Caprio, Marica; Manni, Isabella; Chiappa, Michela; Sergio, Ilaria; Chiacchiarini, Martina; Bazzichetto, Chiara; Conciatori, Fabiana; D'aguanno, Simona; D'angelo, Carmen; Ragno, Rino; Russillo, Michelangelo; Colotti, Gianni; Marchesi, Francesco; Bellone, Maria Laura; Dal Piaz, Fabrizio; Felli, Maria Pia; Damia, Giovanna; Del Bufalo, Donatella - 01a Articolo in rivista

rivista: CELL DEATH & DISEASE (Nature Group) pp. 1-13 - issn: 2041-4889 - wos: WOS:001031302800002 (13) - scopus: 2-s2.0-85165050023 (13)

11573/1605213 - 2022 - MicroRNAs as modulators of the immune response in T-Cell acute lymphoblastic leukemia

Del Gaizo, M.; Sergio, I.; Lazzari, S.; Cialfi, S.; Pelullo, M.; Screpanti, I.; Felli, M. P. - 01g Articolo di rassegna (Review)

rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000748219800001 (8) - scopus: 2-s2.0-85122783300 (10)

11573/1640763 - 2022 - Signaling Crosstalks Drive Generation and Regeneration of the Thymus

Rosichini, Marco; Catanoso, Marialuigia; Screpanti, Isabella; Felli, Maria Pia; Locatelli, Franco; Velardi, Enrico - 01g Articolo di rassegna (Review)

rivista: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-3224 - wos: WOS:000813003500001 (4) - scopus: 2-s2.0-85132622668 (4)

11573/1662577 - 2022 - Editorial: Thymus function and aging: A focus on thymic epithelial cells

Shichkin, Valentin P; Felli, Maria Pia; Screpanti, Isabella; Antica, Mariastefania - 01m Editorial/Introduzione in rivista

rivista: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. 01-03 - issn: 1664-3224 - wos: WOS:000848532900001 (2) - scopus: 2-s2.0-85137254171 (2)

11573/1602865 - 2021 - Editorial: Targeting developmental pathways in inflammation and disease

Anastasiadou, E.; Minter, L. M.; Felli, M. P. - 01m Editorial/Introduzione in rivista

rivista: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. 1-4 - issn: 2296-634X - wos: WOS:000720530100001 (0) - scopus: 2-s2.0-85119513227 (0)

11573/1567658 - 2021 - When viruses cross developmental pathways

Trivedi, P.; Patel, S. K.; Bellavia, D.; Messina, E.; Palermo, R.; Ceccarelli, S.; Marchese, C.; Anastasiadou, E.; Minter, L. M.; Felli, M. P. - 01g Articolo di rassegna (Review)

rivista: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-634X - wos: WOS:000895965600001 (5) - scopus: 2-s2.0-85113208731 (6)

11573/1602861 - 2021 - Targeting notch to maximize chemotherapeutic benefits: rationale, advanced strategies, and future perspectives

Zhdanovskaya, N.; Firrincieli, M.; Lazzari, S.; Pace, E.; Rossi, P. S.; Felli, M. P.; Talora, C.; Screpanti, I.; Palermo, R. - 01g Articolo di rassegna (Review)

rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000713815300001 (16) - scopus: 2-s2.0-85116745560 (18)

11573/1465904 - 2020 - NOTCH3 signaling is essential for NF-κB activation in TLR-activated macrophages

Lopez-Lopez, S.; Monsalve, E. M.; Romero De Avila, M. J.; Gonzalez-Gomez, J.; Hernandez De Leon, N.; Ruiz-Marcos, F.; Baladron, V.; Nueda, M. L.; Garcia-Leon, M. J.; Screpanti, I.; Felli, M. P.; Laborda, J.; Garcia-Ramirez, J. J.; Diaz-Guerra, M. J. M. - 01a Articolo in rivista

rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000571835200010 (38) - scopus: 2-s2.0-85090393932 (39)

11573/1368078 - 2020 - Molecular Mechanisms of Notch Signaling in Lymphoid Cell Lineages Development: NF-κB and Beyond

Tsaouli, G.; Barbarulo, A.; Vacca, A.; Screpanti, I.; Felli, M. P. - 02a Capitolo o Articolo

libro: Notch signaling in Embriology and Cancer - (978-3-030-36421-2; 978-3-030-36422-9)

11573/1493898 - 2020 - A dynamic role of mastermind-like 1. A journey through the main (path)ways between development and cancer

Zema, S.; Pelullo, M.; Nardozza, F.; Felli, M. P.; Screpanti, I.; Bellavia, D. - 01g Articolo di rassegna (Review)

rivista: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-634X - wos: WOS:000605962100001 (23) - scopus: 2-s2.0-85099142457 (23)

11573/1310873 - 2019 - Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains CRC progression and chemoresistance

Pelullo, Maria; Nardozza, Francesca; Zema, Sabrina; Quaranta, Roberta; Nicoletti, Carmine; Besharat, Zein Mersini; Felli, Maria Pia; Cerbelli, Bruna; D’Amati, Giulia; Palermo, Rocco; Capalbo, Carlo; Talora, Claudio; Di Marcotullio, Lucia; Giannini, Giuseppe; Checquolo, Saula; Screpanti, Isabella; Bellavia, Diana - 01a Articolo in rivista

rivista: CANCER RESEARCH (Philadelphia : American Association for Cancer Research) pp. 5575-5586 - issn: 1538-7445 - wos: WOS:000494363200013 (27) - scopus: 2-s2.0-85074445960 (27)

11573/1261501 - 2019 - Histone Modifications Drive Aberrant Notch3 Expression/Activity and Growth in T-ALL

Tottone, Luca; Zhdanovskaya, Nadezda; Carmona Pestaña, Álvaro; Zampieri, Michele; Simeoni, Fabrizio; Lazzari, Sara; Ruocco, Valeria; Pelullo, Maria; Caiafa, Paola; Felli, Maria Pia; Checquolo, Saula; Bellavia, Diana; Talora, Claudio; Screpanti, Isabella; Palermo, Rocco - 01a Articolo in rivista

rivista: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. 1-15 - issn: 2234-943X - wos: WOS:000463425600001 (30) - scopus: 2-s2.0-85067443438 (29)

11573/1286431 - 2019 - Notch/CXCR4 partnership in acute lymphoblastic leukemia progression

Tsaouli, Georgia; Ferretti, Elisabetta; Bellavia, Diana; Vacca, Alessandra; Felli, Maria Pia - 01g Articolo di rassegna (Review)

rivista: JOURNAL OF IMMUNOLOGY RESEARCH (Cairo : Hindawi Publishing Corporation) pp. - - issn: 2314-8861 - wos: WOS:000474532000001 (26) - scopus: 2-s2.0-85070206001 (31)

11573/1691318 - 2019 - Notch/{CXCR}4 Partnership in Acute Lymphoblastic Leukemia Progression

Tsaouli, Georgia; Ferretti, Elisabetta; Bellavia, Diana; Vacca, Alessandra; Felli, Maria Pia - 01g Articolo di rassegna (Review)

rivista: JOURNAL OF IMMUNOLOGY RESEARCH (Cairo : Hindawi Publishing Corporation) pp. 5601396- - issn: 2314-7156 - wos: WOS:000474532000001 (27) - scopus: 2-s2.0-85070206001 (31)

11573/1088655 - 2018 - Notch signaling as a therapeutic target for acute lymphoblastic leukemia

Bellavia, Diana; Palermo, Rocco; Felli, Maria Pia; Screpanti, Isabella; Checquolo, Saula - 01g Articolo di rassegna (Review)

rivista: EXPERT OPINION ON THERAPEUTIC TARGETS (--London United Kingdom:Informa Healthcare -London : Ashley, 2002-.) pp. 331-342 - issn: 1472-8222 - wos: WOS:000430074900004 (35) - scopus: 2-s2.0-85045679979 (39)

11573/1119498 - 2018 - Intrathymic Notch3 and CXCR4 combinatorial interplay facilitates T-cell leukemia propagation.

Ferrandino, Francesca; Bernardini, Giovanni; Tsaouli, Georgia; Grazioli, Paola; Campese, Antonio Francesco; Noce, Claudia; Ciuffetta, Ambra; Vacca, Alessandra; Besharat, Zein Mersini; Bellavia, Diana; Screpanti, Isabella; Felli, Maria Pia - 01a Articolo in rivista

rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. - - issn: 0950-9232 - wos: WOS:000452384400001 (31) - scopus: 2-s2.0-85050377995 (30)

11573/1165511 - 2018 - Notch and NF-kB: Coach and Players of Regulatory T-Cell Resposnse in Cancer

Ferrandino, Francesca; Grazioli, Paola; Bellavia, Diana; Campese, Antonio Francesco; Screpanti, Isabella; Felli, Maria Pia - 01a Articolo in rivista

rivista: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. 1-9 - issn: 1664-3224 - wos: WOS:000447039500001 (55) - scopus: 2-s2.0-85055346229 (54)

11573/1166892 - 2018 - "Notch3 and CXCR4 cross-signaling sustains acute T-cell leukemia progression"

Tsaouli, G; Ferrandino, F; Bernardini, G; Grazioli, P; Campese, Af; Bellavia, D; Checquolo, S; Screpanti, I; Felli., Mp - 01h Abstract in rivista

rivista: ESMO OPEN (London: BMJ) pp. A383- - issn: 2059-7029 - wos: (0) - scopus: (0)

11573/960534 - 2017 - The mazy case of Notch and immunoregulatory cells

Grazioli, Paola; Felli, Maria Pia; Screpanti, Isabella; Campese, Antonio Francesco - 01a Articolo in rivista

rivista: JOURNAL OF LEUKOCYTE BIOLOGY (Federation of American Societies for Experimental Biology (FASEB):9650 Rockville Pike, Room L-2310:Bethesda, MD 20814:(800)433-2732, (301)530-7027, EMAIL: staff@dues.faseb.org, INTERNET: http://www.faseb.org, Fax: (301)571-5728, (301)530-7001) pp. 361-368 - issn: 0741-5400 - wos: WOS:000405384800019 (27) - scopus: 2-s2.0-85026731466 (28)

11573/969457 - 2017 - Maml1 acts cooperatively with Gli proteins to regulate Sonic hedgheog signaling pathway

Quaranta, Roberta; Pelullo, Maria; Zema, Sabrina; Nardozza, Francesca; Checquolo, Saula; Lauer, Dieter Matthias; Bufalieri, Francesca; Palermo, Rocco; Felli, Maria Pia; Vacca, Alessandra; Talora, Claudio; Di Marcotullio, Lucia; Screpanti, Isabella; Bellavia, Diana - 01a Articolo in rivista

rivista: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000406870400031 (34) - scopus: 2-s2.0-85035040836 (35)

11573/982167 - 2016 - Notch3 sustains CXCR4 expression in acute T cell lymphoblastic leukemia progression

Ferrandino, Francesca; Bernardini, Giovanni; Grazioli, Paola; Campese, Antonio Francesco; Bellavia, Diana; Checquolo, Saula; Screpanti, Isabella; Felli, Maria Pia - 04c Atto di convegno in rivista

rivista: EUROPEAN JOURNAL OF CANCER (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. S87-S87 - issn: 0959-8049 - wos: WOS:000431649800307 (0) - scopus: (0)

congresso: 24th Biennial Congress of the European Association for Proceedings Book Cancer Research (Manchester, UK)

11573/689288 - 2015 - Multidrug Resistance Protein-4 influences aspirin toxicity in human cell line

Massimi, Isabella; A., Ciuffetta; Temperilli, Flavia; Ferrandino, Francesca; Zicari, Alessandra; Pulcinelli, Fabio Maria; Felli, Maria Pia - 01a Articolo in rivista

rivista: MEDIATORS OF INFLAMMATION (-[S.l.] : Hindawi -Abingdon : Carfax) pp. - - issn: 1466-1861 - wos: WOS:000362737900001 (14) - scopus: 2-s2.0-84944258522 (20)

11573/785323 - 2014 - CXCR4 deregulated expression in Notch3-induced T cell leukemia

Ferrandino, Francesca; Bernardini, Giovanni; Ciuffetta, Ambra; Campese, Antonio Francesco; Grazioli, Paola; Bellavia, Diana; Gulino, Alberto; Screpanti, Isabella; Felli, Maria Pia - 04c Atto di convegno in rivista

rivista: THE AMERICAN JOURNAL OF PATHOLOGY (American Society for Investigative Pathology:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7130, EMAIL: asjp@asip.org, INTERNET: http://www.asip.org, Fax: (301)634-7990) pp. 38-38 - issn: 0002-9440 - wos: (0) - scopus: (0)

congresso: The 2nd Joint Meeting of Pathology and Laboratory Diagnostics (Palermo, Italia)

11573/656612 - 2014 - Notch3/Jagged1 Circuitry Reinforces Notch Signaling and Sustains T-ALL.

Pelullo, Maria; Quaranta, Roberta; Talora, Claudio; Checquolo, Saula; Cialfi, Samantha; Felli, Maria Pia; Te Kronnie, G; Borga, C; Besharat, Zein Mersini; Palermo, Rocco; Di Marcotullio, Lucia; Capobianco, Aj; Gulino, Alberto; Screpanti, Isabella; Bellavia, Diana - 01a Articolo in rivista

rivista: NEOPLASIA (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 1007-1017 - issn: 1522-8002 - wos: WOS:000347172100002 (46) - scopus: 2-s2.0-85003322506 (47)

11573/501387 - 2012 - Deletion of NF-kappa/p50 influences the outcome of Notch3-dependent T cell leukemia

Campese, Antonio Francesco; Grazioli, Paola; Scafetta, Gaia; Noce, Claudia; Verkhovskaia, Sofia; C., Mari; Felli, Maria Pia; Gulino, Alberto; Screpanti, Isabella - 04d Abstract in atti di convegno

rivista: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. - - issn: 0022-1767 - wos: WOS:000304659700473 (0) - scopus: (0)

congresso: 99th Annual Meeting of the American-Association-of-Immunologists (Boston, MA)

11573/501906 - 2012 - The Outcome of Notch3-dependent T Cell Leukemia Is Modified By NF-kappaB Deletion

Campese, Antonio Francesco; Grazioli, Paola; Scafetta, Gaia; Noce, Claudia; Verkhovskaia, Sofia; C., Mari; Felli, Maria Pia; Gulino, Alberto; Screpanti, Isabella - 04d Abstract in atti di convegno

congresso: XXXI Congress of the Italian Society of Pathology and Translational Medicine (Udine, Italia)

11573/354695 - 2011 - Notch3 and canonical NF-κB signaling pathways cooperatively regulate Foxp3 transcription

Barbarulo, Alessandro; Grazioli, Paola; Campese, Antonio Francesco; Bellavia, Diana; Giuseppina Di, Mario; Pelullo, Maria; Ciuffetta, Ambra; Colantoni, Sara; Vacca, Alessandra; Frati, Luigi; Gulino, Alberto; Felli, Maria Pia; Screpanti, Isabella - 01a Articolo in rivista

rivista: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 6199-6206 - issn: 0022-1767 - wos: WOS:000290755700018 (60) - scopus: 2-s2.0-79958058411 (62)

11573/363403 - 2011 - Aspirin Extrusion From Human Platelets Through Multidrug Resistance Protein-4-Mediated Transport Evidence of a Reduced Drug Action in Patients After Coronary Artery Bypass Grafting

Mattiello, Teresa; Raffaella, Guerriero; Lotti, Lavinia Vittoria; Trifirò, Elisabetta; Felli, Maria Pia; Barbarulo, Alessandro; Bruna, Pucci; Gazzaniga, Paola; Gaudio, Carlo; Frati, Luigi; Pulcinelli, Fabio Maria - 01a Articolo in rivista

rivista: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY ([New York N.Y.]: Elsevier Biomedical Philadelphia, PA: W B Saunders Company) pp. 752-761 - issn: 0735-1097 - wos: WOS:000293455300016 (71) - scopus: 2-s2.0-79961185454 (83)

11573/228912 - 2008 - Notch3: from subtle structural differences to functional diversity

Bellavia, Diana; Checquolo, Saula; Campese, Antonio Francesco; Felli, Maria Pia; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista

rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 5092-5098 - issn: 0950-9232 - wos: WOS:000258914900002 (64) - scopus: 2-s2.0-50849112357 (68)

11573/224173 - 2008 - Notch signaling and diseases: An evolutionary journey from a simple beginning to complex outcomes

Talora, Claudio; Campese, Antonio Francesco; Bellavia, Diana; Felli, Maria Pia; Vacca, Alessandra; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista

rivista: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 489-497 - issn: 0925-4439 - wos: WOS:000259287300001 (70) - scopus: 2-s2.0-49349097988 (72)

11573/501328 - 2007 - Notch3 and pre-TCR interaction differentially regulate T cell development and leukemogenesis

Bellavia, Diana; Campese, Antonio Francesco; Talora, Claudio; Checquolo, Saula; Vacca, Alessandra; Felli, Maria Pia; Gulino, Alberto; Screpanti, Isabella - 04c Atto di convegno in rivista

rivista: IMMUNOLOGY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 33-33 - issn: 0019-2805 - wos: WOS:000244080000127 (0) - scopus: (0)

congresso: Annual Congress of the British-Society-of-Immunology (Glasgow, SCOTLAND)

11573/362204 - 2006 - Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.

Vacca, Alessandra; Felli, Maria Pia; Palermo, Rocco; Di Mario, G; Calce, A; Di Giovine, Monica; Frati, Luigi; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista

rivista: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 1000-1008 - issn: 0261-4189 - wos: WOS:000236225400008 (121) - scopus: 2-s2.0-33644864057 (122)

11573/358248 - 2005 - PKC theta mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia

Felli, Maria Pia; Vacca, Alessandra; Calce, A; Bellavia, Diana; Campese, Antonio Francesco; Grillo, R; Di Giovine, M; Checquolo, Saula; Talora, Claudio; Palermo, Rocco; Di Mario, G; Frati, Luigi; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista

rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 992-1000 - issn: 0950-9232 - wos: WOS:000226749200005 (63) - scopus: 2-s2.0-13944266008 (68)

11573/250440 - 2000 - Constitutive activation of NF-kB and T-cell leukemia/lymphoma in Notch3 transgenic mice

Bellavia, Diana; Campese, Antonio Francesco; Alesse, E.; Vacca, Alessandra; Felli, Maria Pia; Balestri, A.; Stoppacciaro, Antonella; Tiveron, C.; Tatangelo, L.; Giovarelli, M.; Gaetano, C.; Ruco, Luigi; Hoffman, E. S.; Hayday, A. C.; Lendahl, U.; Frati, Luigi; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista

rivista: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 3337-3348 - issn: 0261-4189 - wos: WOS:000088132600017 (311) - scopus: 2-s2.0-0034600850 (318)

11573/253397 - 2000 - The thymus at the crossroad of the neuroimmune interactions

Maroder, Marella; Bellavia, Diana; Vacca, Alessandra; Felli, Maria Pia; Screpanti, Isabella - 01a Articolo in rivista

rivista: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (New York: New York Academy of Sciences) pp. 741-747 - issn: 0077-8923 - wos: WOS:000171939400072 (23) - scopus: 2-s2.0-0033671102 (26)

11573/362083 - 2000 - Identification of an estrogen-mediated deoxyribonucleic acid-binding independent transactivation pathway on the epidermal growth factor receptor gene promoter.

Salvatori, Luisa; Ravenna, Linda Ester; Felli, Maria Pia; Cardillo, Maria Rosaria; Russo, Matteo Antonio; Frati, Luigi; Petrangeli, Elisa - 01a Articolo in rivista

rivista: ENDOCRINOLOGY (Endocrine Society / Maryland:8401 Connecticut Avenue, Suite 900:Chevy Chase, MD 20815:(301)941-0200, (301)941-0200, (301)941-0232, EMAIL: journals@endo-society.org, INTERNET: http://www.endo.society.org, Fax: (301)941-0259) pp. 2266-2274 - issn: 0013-7227 - wos: WOS:000088386100049 (39) - scopus: 2-s2.0-0034456445 (36)

11573/250446 - 2000 - Expression of metabotropic glutamate receptors in murine thymocytes and thymic stromal cells

Storto, Marianna; De Grazia, Ugo; Battaglia, Giuseppe; Felli, Maria Pia; Maroder, Marella; Gulino, Alberto; Ragona, Giuseppe; Nicoletti, Ferdinando; Screpanti, Isabella; Frati, Luigi; Calogero, Antonella - 01a Articolo in rivista

rivista: JOURNAL OF NEUROIMMUNOLOGY (Amsterdam ; Lausanne ; New York ; Oxford ; Shannon ; Tokyo : Elsevier) pp. 112-120 - issn: 0165-5728 - wos: WOS:000089577000009 (65) - scopus: 2-s2.0-0034703190 (73)

11573/241738 - 1999 - Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

Felli, Maria Pia; Maroder, Marella; T. A., Mitsiadis; Campese, Antonio Francesco; Bellavia, Diana; Vacca, Alessandra; R. S., Mann; Frati, Luigi; U., Lendahl; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista

rivista: INTERNATIONAL IMMUNOLOGY (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 1017-1025 - issn: 0953-8178 - wos: WOS:000081780300002 (167) - scopus: 2-s2.0-0032798711 (166)

11573/241744 - 1996 - Prostaglandin E2 inhibits the interleukin-2 promoter activity through down-regulation of the oct-dependent transcription of the octamer motif.

Felli, Maria Pia; Moschella, C.; Farina, A. R.; Alesse, E.; Screpanti, Isabella; Teti, D.; Frati, Luigi; Gulino, Alberto - 01a Articolo in rivista

rivista: CELLULAR IMMUNOLOGY (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 229-234 - issn: 0008-8749 - wos: WOS:A1996VJ54200012 (5) - scopus: 2-s2.0-0030587154 (6)

11573/244891 - 1995 - ANDROGENIC AND ANTIANDROGENIC CONTROL ON EPIDERMAL GROWTH-FACTOR, EPIDERMAL GROWTH-FACTOR RECEPTOR, AND ANDROGEN RECEPTOR EXPRESSION IN HUMAN PROSTATE-CANCER CELL-LINE LNCAP

Ravenna, Linda Ester; Lubrano, Carla; Di Silverio, Franco; Vacca, Alessandra; Felli, Maria Pia; Maroder, Marella; D'eramo, Giuseppe; Sciarra, Francesco; Frati, Luigi; Gulino, Alberto; Petrangeli, Elisa - 01a Articolo in rivista

rivista: THE PROSTATE (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 290-298 - issn: 0270-4137 - wos: WOS:A1995RR55700002 (30) - scopus: 2-s2.0-0028998283 (28)

11573/244776 - 1994 - Positive and negative regulation of the composite octamer motif of the interleukin 2 enhancer by AP-1, OCT-2, and Retinoic Acid Receptor.

De Grazia, Ugo; Felli, Maria Pia; Vacca, Alessandra; Farina, A. R.; Maroder, Marella; Cappabianca, L.; Meco, D.; Farina, M.; Screpanti, Isabella; Frati, Luigi; Gulino, Alberto - 01a Articolo in rivista

rivista: JOURNAL OF EXPERIMENTAL MEDICINE (Baltimore Md.: Rockefeller Institute for Medical Research) pp. 1485-1497 - issn: 0022-1007 - wos: WOS:A1994PJ70300031 (40) - scopus: 2-s2.0-0028018364 (45)

11573/383630 - 1993 - REGULATION OF INTERLEUKIN-2 GENE-TRANSCRIPTION BY NUCLEAR HORMONE RECEPTORS

Gulino, Alberto; Vacca, Alessandra; Felli, Maria Pia; D., Meco; U., De Grazia; Maroder, Marella; Screpanti, Isabella; Martinotti, Stefano; Frati, Luigi - 01a Articolo in rivista

rivista: JOURNAL OF CELLULAR BIOCHEMISTRY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 159-159 - issn: 0730-2312 - wos: WOS:A1993KN46400583 (0) - scopus: (0)

11573/388667 - 1993 - CELL-SPECIFIC BIFUNCTIONAL ROLE OF JUN ONCOGENE FAMILY MEMBERS ON GLUCOCORTICOID RECEPTOR-DEPENDENT TRANSCRIPTION

Maroder, Marella; A. R., Farina; Vacca, Alessandra; Felli, Maria Pia; D., Meco; Screpanti, Isabella; Frati, Luigi; Gulino, Alberto - 01a Articolo in rivista

rivista: MOLECULAR ENDOCRINOLOGY (Endocrine Society / Maryland:8401 Connecticut Avenue, Suite 900:Chevy Chase, MD 20815:(301)941-0200, (301)941-0200, (301)941-0232, EMAIL: journals@endo-society.org, INTERNET: http://www.endo.society.org, Fax: (301)941-0259) pp. 570-584 - issn: 0888-8809 - wos: WOS:A1993LA06400011 (67) - scopus: 2-s2.0-0027298679 (67)

11573/246699 - 1993 - Nuclear hormone receptor interference with interleukin 2 promoter activating signals

Vacca, Alessandra; Felli, Maria Pia; A. R., Farina; D., Meco; Maroder, Marella; Screpanti, Isabella; Martinotti, Stefano; Petrangeli, Elisa; De Grazia, Ugo; Frati, Luigi; Gulino, Alberto - 02a Capitolo o Articolo

libro: Progress in Endocrinology - (1850704694)

11573/256137 - 1992 - Glucocorticoid receptor-mediated suppression of the interleukin 2 gene expression through impairement of the cooperativity between NuclearFactor of Activated T cells and AP-1 enhancer elements

Vacca, Alessandra; Felli, Maria Pia; Farina, A. R.; Martinotti, Stefano; Maroder, Marella; Screpanti, Isabella; Meco, D.; Petrangeli, Elisa; Frati, Luigi; Gulino, Alberto - 01a Articolo in rivista

rivista: JOURNAL OF EXPERIMENTAL MEDICINE (Baltimore Md.: Rockefeller Institute for Medical Research) pp. 637-646 - issn: 0022-1007 - wos: WOS:A1992HF64000002 (235) - scopus: 2-s2.0-0026507209 (239)

11573/49010 - 1991 - Inheritance of ribosomal gene activity and level of DNA methylation of individual gene clusters in a three generation family

De Capoa, Adriana; Aleixandre, C.; Felli, Maria Pia; Ravenna, Linda Ester; Costantino, M. A.; Giancotti, Paola; Vicenti, O.; Poggesi, I.; Grappelli, Claudio; Miller, D. A. - 01a Articolo in rivista

rivista: HUMAN GENETICS (Germany: Springer Verlag Germany) pp. 146-152 - issn: 0340-6717 - wos: WOS:A1991GV39000005 (25) - scopus: 2-s2.0-0026409358 (28)

11573/244175 - 1991 - RETINOIC ACID-INDUCED DOWN-REGULATION OF THE INTERLEUKIN-2 PROMOTER VIA CIS-REGULATORY SEQUENCES CONTAINING AN OCTAMER MOTIF

Felli, Maria Pia; Vacca, Alessandra; D., Meco; Screpanti, Isabella; A. R., Farina; Maroder, Marella; Martinotti, Stefano; Petrangeli, Elisa; Frati, Luigi; Gulino, Alberto - 01a Articolo in rivista

rivista: MOLECULAR AND CELLULAR BIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 4771-4778 - issn: 0270-7306 - wos: WOS:A1991GC39600055 (64) - scopus: 2-s2.0-0025827075 (62)

11573/388113 - 1991 - ENHANCEMENT OF NATURAL-KILLER-CELL SUSCEPTIBILITY OF HUMAN BREAST-CANCER CELLS BY ESTRADIOL AND V-HA-RAS ONCOGENE

Screpanti, Isabella; Felli, Maria Pia; E., Toniato; D., Meco; Martinotti, Stefano; Frati, Luigi; Santoni, Angela; Gulino, Alberto - 01a Articolo in rivista

rivista: INTERNATIONAL JOURNAL OF CANCER (Hoboken N.J.: Wiley New York NY: Wiley-Liss) pp. 445-449 - issn: 0020-7136 - wos: WOS:A1991FA21000022 (13) - scopus: 2-s2.0-0026012872 (13)

11573/386137 - 1990 - Transcriptional regulation of the interleukin 2 gene by glucocorticoid hormones. Role of steroid receptor and antigen-responsive 5'-flanking sequences.

Vacca, Alessandra; Martinotti, S; Screpanti, Isabella; Maroder, Marella; Felli, Maria Pia; Farina, Ar; Gismondi, Angela; Santoni, Angela; Frati, Luigi; Gulino, Alberto - 01a Articolo in rivista

rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 8075-8080 - issn: 0021-9258 - wos: WOS:A1990DC83500058 (85) - scopus: 2-s2.0-0025267774 (80)

11573/48175 - 1988 - Differential ribosomal gene responsiveness to human growth hormone is visualized by selective silver staining

Baldini, A.; Felli, Maria Pia; Ravenna, Linda Ester; Camaioni, A.; De Capoa, Adriana; Spadoni, G. L.; Cianfarani, S.; Boscherini, B. - 01a Articolo in rivista

rivista: CYTOGENETICS AND CELL GENETICS (S Karger AG:Allschwilerstrasse 10, CH-4009 Basel Switzerland:011 41 61 3061111, EMAIL: orders@karger.ch, INTERNET: http://www.karger.com, Fax: 011 41 61 3061234) pp. 22-25 - issn: 0301-0171 - wos: WOS:A1988M992400007 (3) - scopus: 2-s2.0-0023776498 (4)

11573/49005 - 1988 - RELATIONSHIP BETWEEN THE NUMBER AND FUNCTION OF HUMAN RIBOSOMAL GENES

De Capoa, Adriana; Felli, Maria Pia; A., Baldini; M., Rocchi; N., Archidiacono; C., Aleixandre; O. J., Mille; D. A., Miller - 01a Articolo in rivista

rivista: HUMAN GENETICS (Germany: Springer Verlag Germany) pp. 301-304 - issn: 0340-6717 - wos: WOS:A1988P703400004 (25) - scopus: 2-s2.0-0023734931 (26)

11573/49006 - 1988 - Laron dwarfism: cellular unresponsiveness to GH demonstrated on cultured lymphocytes by a cytochemical method

Spadoni, G. L.; Cianfarani, S.; Baldini, A.; Ravenna, Linda Ester; Felli, Maria Pia; Camaioni, A.; Manca Bitti, M. L.; Scirè, G.; Boscherini, B.; De Capoa, Adriana - 01a Articolo in rivista

rivista: HORMONE AND METABOLIC RESEARCH (Stuttgart Germany: Georg Thieme Verlag Stuttgart) pp. 450-452 - issn: 0018-5043 - wos: WOS:A1988P537900015 (8) - scopus: 2-s2.0-0023748443 (8)

11573/49003 - 1986 - Growth hormone-induced activation of rRNA gene clusters:cellular responses of normal subjects and pituitaric dwarfs.

Baldini, A.; Camaioni, A.; De Capoa, A.; Felli, Maria Pia; Marlekaj, P.; Ravenna, Linda Ester; Cianfarani, S.; Spadoni, G. L.; Boscherini, B. - 01a Articolo in rivista

rivista: CELL BIOLOGY INTERNATIONAL REPORTS (Academic Press Limited:32 Jamestown Road, London NW1 7BY United Kingdom:011 44 207 4244200, EMAIL: apjcs@harcourtbrace.com, INTERNET: http://www.apnet.com, Fax: 011 44 207 2670362) pp. 202-202 - issn: 0309-1651 - wos: (0) - scopus: (0)

11573/49004 - 1986 - Growth hormone-induced regulation of rRNA gene activity in human cultured cells.

De Capoa, Adriana; P., Marlekaj; A., Baldini; Felli, Maria Pia; M., Rocchi; N., Archidiacono; S., Cianfarani; G. L., Spadoni; Brunetto, Boscherini - 01a Articolo in rivista

rivista: HORMONE AND METABOLIC RESEARCH (Stuttgart Germany: Georg Thieme Verlag Stuttgart) pp. 574-575 - issn: 0018-5043 - wos: WOS:A1986D806400016 (3) - scopus: 2-s2.0-0022516017 (3)