MARCO TOCCI

Dottore di ricerca

ciclo: XXXVII

Titolo della tesi: VALUE OF OXIDATIVE-STRESS PARAMETERS ON CARDIAC FUNCTION AND CLINICAL OUTCOMES OF PATIENTS UNDERGOING TRANSCATHETER AORTIC VALVE REPLACEMENT

Background: The purpose of this study was to evaluate the changes in NOX2, a marker of oxidative stress, in patients before and after Transcatheter Aortic Valve Replacement (TAVR). Methods: We enrolled 63 patients in our centre in 2023 and investigated the correlations between changes in oxidative stress, improvements in echocardiographic parameters, and clinical endpoints. NOX2 levels were measured at baseline, 48 hours, and 1 month post-TAVR. Results: Oxidative stress, as indicated by NOX2 levels, was significantly reduced at 48 hours and 1 month after TAVR. Despite these substantial reductions, no differences were observed in cardiovascular mortality at 6 months or in improved transprosthetic gradients. However, a significant association was found between the marked improvement in oxidative stress and the enhancement of ejection fraction. Conclusions: TAVR significantly reduces oxidative stress shortly after the procedure. While these reductions are not linked to decreased cardiovascular mortality or improved transprosthetic gradients at 6 months, they are associated with better ejection fraction outcomes, suggesting a beneficial impact on cardiac function.

Produzione scientifica

11573/1735709 - 2024 - The impact of vaccination status on post-acute sequelae in hospitalized COVID-19 survivors using a multi-disciplinary approach: An observational single center study

Birtolo, Lucia Ilaria; Di Pietro, Gianluca; Ciuffreda, Antonella; Improta, Riccardo; Monosilio, Sara; Prosperi, Silvia; Cimino, Sara; Galea, Nicola; Severino, Paolo; Galardo, Gioacchino; Colaiacomo, Maria Chiara; Pasculli, Patrizia; Petroianni, Angelo; Palange, Paolo; Mastroianni, Claudio Maria; De Vito, Laura; Catalano, Carlo; Pugliese, Francesco; Ciardi, Maria Rosa; Celli, Paola; Badagliacca, Roberto; Fedele, Francesco; Vizza, Carmine Dario; Maestrini, Viviana; Mancone, Massimo; Agnes, Gianluca; Albante, Alida; Alfarano, Maria; Fabio, Araimo Morselli; Daniela, Auricchio; Barletta, Giovanna; Bilotta, Federico; Brisciani, Matteo; Katia, Bruno; Bucarelli, Maria Clelia; Cappannoli, Alessandro; Ceccarelli, Giancarlo; Paola, Celli; Consolo, Maria Stella; Giulia, Consoli; Claudia, Croce; Crocitti, Beatrice; Letizia, D'antoni; De Lazzaro, Francesco; De Lauri, Daniela; Francesca, De Persis; De Rose, Maria; Del Bianco, Andrea; Di Bella, Valerio; Di Sano, Laura; Di Santo, Carmela; Filomena, Domenico; Lorena, Giannetti; Giovanni, Giordano; Ianni, Stefano; Carmela, Imperiale; Magnanimi, Eugenia; Manganelli, Chiara; Maldarelli, Federica; Manzi, Giovanna; Serena, Marcon; Mariani, Marco Valerio; Martelli, Sabina; Teresa, Messina; Matteo, Neccia; Martina, Novelli; Papa, Silvia; Pasqualitto, Fabiola; Pattelli, Elisa; Pecorari, Filippo; Perrella, Serena Maria; Passarelli, Ilaria; Piazzolla, Mario; Piro, Agostino; Monica, Portieri; Fabiola, Ratini; Claudia, Ricci; Romano, Hilde; Anna, Sabani; Santopietro, Pietro; Tanzilli, Alessandra; Tellan, Guglielmo; Titi, Luca; Tocci, Marco; Paolo, Tordiglione; Tosi, Antonella; Trigilia, Fausto; Verduci, Noemi; Paola, Vaccaro - 01a Articolo in rivista

rivista: HELIYON (Cell Press United Kingdom: Elsevier Limited) pp. - - issn: 2405-8440 - wos: (0) - scopus: 2-s2.0-85209239107 (0)

11573/1726157 - 2024 - Transcatheter Aortic Valve Replacement in Low Surgical Risk Patients: An Updated Metanalysis of Extended Follow-Up Randomized Controlled Trials

Di Pietro, Gianluca; Improta, Riccardo; De Filippo, Ovidio; Bruno, Francesco; Birtolo, Lucia Ilaria; Tocci, Marco; Fabris, Tommaso; Saade, Wael; Colantonio, Riccardo; Celli, Paola; Sardella, Gennaro; Esposito, Giovanni; Tarantini, Giuseppe; Mancone, Massimo; D’Ascenzo, Fabrizio - 01a Articolo in rivista

rivista: THE AMERICAN JOURNAL OF CARDIOLOGY (NY : Elsevier Science Incorporated / NY; EXCERPTA MEDICA INC) pp. - - issn: 0002-9149 - wos: (0) - scopus: (0)

11573/1740973 - 2024 - Invasive and conservative management of elderly patients presenting with acute coronary syndrome: A meta-analysis of randomized controlled trials and adjusted observational studies

Improta, Riccardo; Di Pietro, Gianluca; Piccialuti, Alice; De Filippo, Ovidio; Birtolo, Lucia Ilaria; Severino, Paolo; Tocci, Marco; Saade, Wael; Cammertoni, Federico; Vizza, Carmine Dario; Sardella, Gennaro; D'ascenzo, Fabrizio; Stefanini, Giulio; Mancone, Massimo - 01a Articolo in rivista

rivista: INTERNATIONAL JOURNAL OF CARDIOLOGY (Shannon; Amsterdam: Elsevier Science Publishers; Elsevier/North-Holland) pp. - - issn: 0167-5273 - wos: WOS:001314130000001 (4) - scopus: 2-s2.0-85203446040 (0)

11573/1645178 - 2022 - Prognostic value of systemic inflammatory response syndrome after transcatheter aortic valve implantation

Monosilio, S.; Filomena, D.; Cimino, S.; Birtolo, L. I.; Tocci, M.; Mancone, M.; Sardella, G.; Fedele, F.; Maestrini, V.; Agati, L. - 01a Articolo in rivista

rivista: JOURNAL OF CARDIOVASCULAR MEDICINE (Hagerstown, MD : Lippincott Williams & Wilkins, c2006-) pp. 394-398 - issn: 1558-2035 - wos: WOS:000802116800007 (0) - scopus: 2-s2.0-85131225411 (1)

11573/1458762 - 2020 - Coronavirus disease 2019 in Rome: was it circulating before December?

Birtolo, L. I.; Maestrini, V.; Severino, P.; Chimenti, C.; Agnes, G.; Tocci, M.; Colaiacomo, M. C.; Francone, M.; Mancone, M.; Fedele, F. - 01f Lettera, Nota

rivista: JOURNAL OF CARDIOVASCULAR MEDICINE (Hagerstown, MD : Lippincott Williams & Wilkins, c2006-) pp. 835-836 - issn: 1558-2035 - wos: WOS:000619297600019 (5) - scopus: 2-s2.0-85090508315 (6)