LUCIA DI MARCOTULLIO

Full professor

email: lucia.dimarcotullio@uniroma1.it
phone: 06 49255657
building: Regina Elena
room: 219

Personal data and CV

Name: Lucia
Surname: Di Marcotullio
Citizenship: Italian
Work address: Department of Molecular Medicine, Sapienza University,
Viale Regina Elena, 291 – 00161 Rome
Present Position: Full Professor MED/46
Email address: lucia.dimarcotullio@uniroma1.it
Phone: 0039-06 49255657 - Fax: 0039-06 49255660

EDUCATION and TRAINING
1994: Graduation, Summa cum Laude, Faculty of Biology, Sapienza University, Rome
1994-1999: Ph.D. in Experimental Medicine, University of L'Aquila
1999-2002: Post-doctoral Fellow in the group of Michele Pagano, Department of Pathology, New York University School of Medicine, New York, NY
1999-2000: Awarded of one year felloship from the FIRC (Fondazione Italiana Ricerca sul Cancro)
2000-2001: Awarded of one year felloship from the AICF (American-Italian Cancer Foundation), renewed for the academic year 2001-2002
2002-2004: Fellow in the group of prof. Alberto Gulino, Dept of Experimental Medicine and Pathology Sapienza University, Rome.
2005-2012: Assistant Professor, MED/04, Dept of Experimental Medicine, Sapienza University, Rome
december 2012: Associate Professor, MED/04, Dept of Molecular Medicine, Sapienza University, Rome from 27/5/2015 Associate Professor, MED/46, Dept of Molecular Medicine, Sapienza University, Rome
2014: ASN (Abilitazione Scientifica Nazionale), settore concorsuale 06/N1
2017: ASN (Abilitazione Scientifica Nazionale), settore concorsuale 06/A2
2018-present: Full Professor, MED/46, Dept of Molecular Medicine, Sapienza University, Rome

MAIN RESEARCH FIELDS
Dr. Di Marcotullio's expertise and qualification in several fields of research are:
- Role of ubiquitination and proteolysis processes in development and tumorigenesis.
- Identification and characterization of miRNAs in controlling Hedgehog signaling pathway and medulloblastoma e/o neuroblastoma tumorigenesis; identification and characterization of microRNA as biomarkers and co-adjuvant treatment for cancer and genetic disease
- Characterization of the molecular events involved in brain tumorigenesis mainly focusing on medulloblastoma and dysregulated pathways (i.e. Hedgehog/Gli) controlling progenitor cell development.
- Identification and design of novel molecular drugs effective in the treatment of Hedgehog-dependent tumors.

COLLABORATIONS (International and national)
- Olivier Ayrault, Institut Curie, PSL Research University, Université Paris Sud, Université Paris-Saclay, Orsay, France
- Stefan Pfister, Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ)
and German Cancer Consortium (DKTK), Heidelberg, Germany
- Vincenzo D’Angiolella, Department of Oncology, Medical Research Council Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom.
- Natalia Riobo Del Galdo, Leeds Institute of Medical Research, University of Leeds, Leeds, UK.
- Francesca Bartolini, Department of Cell Biology, Columbia University Medica Center, New York, NY
- Doriana Fruci, Paediatric Haematology/Oncology Department, Ospedale Pediatrico Bambino Gesù, Rome, Italy.
- Simonetta Pazzaglia, Laboratory of Biomedical Technologies, Agenzia Nazionale per le Nuove Tecnologie, l’Energia e lo Sviluppo Economico Sostenibile (ENEA), Rome
- Barbara Stecca, Istituto Toscano Tumori, Firenze, Italy
- Massimo Zollo, Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università Federico II di Napoli, Naple, Italy
- Daniele Guardavaccaro, Department of Biotechnology, University of Verona, Verona, Italy

SUMMARY OF SCIENTIFIC ACHIEVEMENTS
Papers: 93 (58 in the last 10 years)
Patents: 3
Hirsh index: 36 (Scopus, WoS) (30 in the last 15 years)
Total citations: 4327 (2868 in the last 15 years)


PATENTS
- US10093642B2 09.10.2018 Granted
Multitarget Hedgehog pathway inhibitors and uses thereof
- PCT EP2019/052800 12.02.2019; US 16/967,006 08.03.2020
Compounds for use in the treatment of brain diseases
- PCT/IB2019/052820 10.09.2020
Identification of muscular MIRNAs as biomarkers and co-adjuvant treatment for spinal muscular atrophy


SELECTED PUBLICATIONS (last 5 years)

Infante P, Malfanti A, Quaglio D, Balducci S, De Martin S, Bufalieri F, Mastrotto F, Basili I, Garofalo M, Lospinoso Severini L, Mori M, Manni I, Moretti M, Nicoletti C, Piaggio G, Caliceti P, Botta B, Ghirga F, Salmaso S, Di Marcotullio L. Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma. Cancer Lett. 2021 Feb 28;499:220-231. doi: 10.1016/j.canlet.2020.11.028 IF. 8,679

Di Magno L, Manni S, Di Pastena F, Coni S, Macone A, Cairoli S, Sambucci M, Infante P, Moretti M, Petroni M, Nicoletti C, Capalbo C, De Smaele E, Di Marcotullio L, Giannini G, Battistini L, Goffredo BM, Iorio E, Agostinelli E, Maroder M, Canettieri G. Phenformin inhibits Hedgehog-dependent tumor growth through a complex I-indipendent redox/corepressor module. Cell Rep. 2020 Feb 11;30(6):1735-1752.e7. doi: 10.1016/j.celrep.2020.01.024 IF: 9.423

Bufalieri F, Infante P, Bernardi F, Caimano M, Romania P, Moretti M, Lospinoso Severini L, Talbot J, Melaiu O, Tanori M, Di Magno L, Bellavia D, Capalbo C, Puget S, De Smaele E, Canettieri G, Guardavaccaro D, Busino L, Peschiaroli A, Pazzaglia S, Giannini G, Melino G, Locatelli F, Gulino A, Ayrault O, Fruci D, Di Marcotullio L. ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP. Nat Comm 2019 Jul 24;10(1):3304. doi: 10.1038/s41467-019-11093-0. IF. 14,919

Infante P, Faedda R, Bernardi F, Bufalieri F, Lospinoso Severini L, Alfonsi R, Mazzà D, Siler M, Coni S, Po A, Petroni M, Ferretti E, Mori M, De Smaele E, Canettieri G, Capalbo C, Maroder M, Screpanti I, Kool M, Pfister SM, Guardavaccaro D, Gulino A, Di Marcotullio L. Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis. Nat Comm 2018 Mar 7;9(1):976. doi: 10.1038/s41467-018-03339-0. IF. 14,919

Infante P, Mori M, Alfonsi R, Ghirga F, Aiello F, Toscano S, Ingallina C, Siler M, Cucchi D, Po A, Miele E, D'Amico D, Canettieri G, De Smaele E, Ferretti E, Screpanti I, Uccello Barretta G, Botta M, Botta B, Gulino A, Di Marcotullio L. Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors. EMBO J. 2015 Jan 14;34(2):200-17. doi: 10.15252/embj.201489213. IF 11.598

D'Amico D, Antonucci L, Di Magno L, Coni S, Sdruscia G, Macone A, Miele E, Infante P, Di Marcotullio L, De Smaele E, Ferretti E, Ciapponi L, Giangaspero F, Yates JR 3rd, Agostinelli E, Cardinali B, Screpanti I, Gulino A, Canettieri G. Non-canonical Hedgehog/AMPK-mediated control of polyamine metabolism supports neuronal and medulloblastoma growth. Dev Cell. 2015 Oct 12;35(1):21-35. doi: 10.1016/j.devcel.2015.09.008. IF: 12.27





Research products

11573/1613696 - 2022 - ERAP1 as an emerging therapeutic target for medulloblastoma
Fruci, Daniela; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: TRENDS IN CANCER (Elsevier B.V.) pp. 4-8 - issn: 2405-8033 - wos: WOS:000734833700002 (0) - scopus: 2-s2.0-85120624748 (0)

11573/1631459 - 2022 - Proteolysis-Targeting Chimera (PROTAC): Is the Technology Looking at the Treatment of Brain Tumors?
Lospinoso Severini, Ludovica; Bufalieri, Francesca; Infante, Paola; Di Marcotullio, Lucia - 01g Articolo di rassegna (Review)
paper: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. 854352- - issn: 2296-634X - wos: WOS:000770668600001 (0) - scopus: 2-s2.0-85125677503 (0)

11573/1472828 - 2021 - Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma
Infante, Paola; Quaglio, Deborah; Balducci, Silvia; Bufalieri, Francesca; Basili, Irene; Lospinoso Severini, Ludovica; Moretti, Marta; Nicoletti, Carmine; Caliceti, Paolo; Botta, Bruno; Ghirga, Francesca; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: CANCER LETTERS (Elsevier Science Ireland Limited:PO Box 85, Limerick Ireland:011 353 61 709600, 011 353 61 61944, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 353 61 709114) pp. 220-231 - issn: 0304-3835 - wos: WOS:000604424500023 (11) - scopus: 2-s2.0-85097086576 (13)

11573/1560455 - 2021 - Design and synthesis of new withaferin A inspired hedgehog pathway inhibitors
Infante, Paola; Basili, Irene; Di Marcotullio, Lucia; Calcaterra, Andrea; Botta, Bruno; Passarella, Daniele - 01a Articolo in rivista
paper: CHEMISTRY-A EUROPEAN JOURNAL (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 8350-8357 - issn: 0947-6539 - wos: WOS:000646619600001 (1) - scopus: 2-s2.0-85105325845 (1)

11573/1560767 - 2021 - Harnessing the activation of RIG-I like receptors to inhibit glioblastoma tumorigenesis
Bufalieri, Francesca; Basili, Irene; Di Marcotullio, Lucia; Infante, Paola - 01g Articolo di rassegna (Review)
paper: FRONTIERS IN MOLECULAR NEUROSCIENCE (Lausanne: Frontiers Research Foundation, 2008-) pp. - - issn: 1662-5099 - wos: WOS:000675519000001 (1) - scopus: 2-s2.0-85111069951 (1)

11573/1613663 - 2021 - SMA-miRs (MiR-181a- 5p, -324-5p, and -451a) are overexpressed in spinal muscular atrophy skeletal muscle and serum samples
Infante, Paola; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: ELIFE (Cambridge: eLife Sciences Publications) pp. - - issn: 2050-084X - wos: WOS:000703785000001 (1) - scopus: 2-s2.0-85116897057 (2)

11573/1613665 - 2021 - Drug delivery systems for hedgehog inhibitors in the treatment of SHH-medulloblastoma
Caimano, Miriam; Lospinoso Severini, Ludovica; Loricchio, Elena; Infante, Paola; Di Marcotullio, Lucia - 01g Articolo di rassegna (Review)
paper: FRONTIERS IN CHEMISTRY (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-2646 - wos: WOS:000663813400001 (6) - scopus: 2-s2.0-85108348605 (6)

11573/1613699 - 2021 - A new smoothened antagonist bearing the purine scaffold shows antitumour activity in vitro and in vivo
Di Marcotullio, Lucia; Loricchio, Elena; Caimano, Miriam; Calcaterra, Andrea - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000690546100001 (4) - scopus: 2-s2.0-85111760377 (4)

11573/1364966 - 2020 - Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module
Di Magno, Laura; Manni, Simona; Di Pastena, Fiorella; Coni, Sonia; Macone, Alberto; Infante, Paola; Moretti, Marta; Petroni, Marialaura; Nicoletti, Carmine; Capalbo, Carlo; De Smaele, Enrico; Di Marcotullio, Lucia; Giannini, Giuseppe; Agostinelli, Enzo; Maroder, Marella; Canettieri, Gianluca - 01a Articolo in rivista
paper: CELL REPORTS (Elsevier B.V.) pp. 1735-1752 - issn: 2211-1247 - wos: WOS:000513920800008 (23) - scopus: 2-s2.0-85079335561 (23)

11573/1384478 - 2020 - The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i
Bufalieri, Francesca; Caimano, Miriam; Basili, Irene; Paglia, Francesco; Sampirisi, Luigi; Loricchio, Elena; Petroni, Marialaura; Canettieri, Gianluca; Santoro, Antonio; Infante, Paola; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: CANCERS (Basel : MDPI) pp. 321- - issn: 2072-6694 - wos: WOS:000522477300067 (25) - scopus: 2-s2.0-85079068523 (25)

11573/1384485 - 2020 - Hedgehog signaling pathway inhibitors: an updated patent review (2015–present)
Quaglio, Deborah; Infante, Paola; Di Marcotullio, Lucia; Botta, Bruno - 01g Articolo di rassegna (Review)
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 235-250 - issn: 1354-3776 - wos: WOS:000514863500001 (21) - scopus: 2-s2.0-85079776320 (20)

11573/1447549 - 2020 - Downregulation of miR-326 and its host gene β-arrestin1 induces pro survival activity of E2F1 and promotes medulloblastoma growth
Po, Agnese; Besharat, Zein Mersini; Pediconi, Natalia; Catanzaro, Giuseppina; Sabato, Claudia; De Smaele, Enrico; Canettieri, Gianluca; Di Marcotullio, Lucia; Vacca, Alessandra; Mai, Antonello; Levrero, Massimo; Giangaspero, Felice; Locatelli, Franco; Ferretti, Elisabetta - 01a Articolo in rivista
paper: MOLECULAR ONCOLOGY (Amsterdam : Elsevier Science) pp. - - issn: 1574-7891 - wos: WOS:000603687900001 (4) - scopus: 2-s2.0-85098446777 (4)

11573/1471575 - 2020 - Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation
Coni, Sonia; Serrao, Silvia Maria; Yurtsever, Zuleyha Nihan; Di Magno, Laura; Bordone, Rosa; Bertani, Camilla; Licursi, Valerio; Ianniello, Zaira; Infante, Paola; Moretti, Marta; Petroni, Marialaura; Fatica, Alessandro; Macone, Alberto; De Smaele, Enrico; Di Marcotullio, Lucia; Giannini, Giuseppe; Maroder, Marella; Agostinelli, Enzo; Canettieri, Gianluca - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000597627300001 (10) - scopus: 2-s2.0-85097416564 (14)

11573/1471927 - 2020 - Nutlin-3a enhances natural killer cell-mediated killing of neuroblastoma by restoring p53-dependent expression of ligands for NKG2D and DNAM-1 receptors
Infante, Paola; Battistelli, Cecilia; Nicoletti, Carmine; Di Marcotullio, Lucia; Barnaba, Vincenzo; Locatelli, Franco - 01a Articolo in rivista
paper: CANCER IMMUNOLOGY RESEARCH (American Association for Cancer Research, Inc. (AACR), 615 Chestnut St., 17th Floor Philadelphia, PA 19106-4404; Phone: (215) 440-9300 or Toll Free: (866) 423-3965; Fax: (215) 446-7289; E-mail: cancerimmunolres@aacr.org.) pp. 170-183 - issn: 2326-6066 - wos: WOS:000618209900006 (13) - scopus: 2-s2.0-85100390757 (12)

11573/1559014 - 2020 - mPEG5kDa-cholane/Glabrescione B delivery system as promising tool for the treatment of Hh-dependent tumors
Vergine, Valeria; Infante, Paola; Quaglio, Deborah; Balducci, Silvia; Bufalieri, Francesca; Basili, Irene; Lospinoso Severini, Ludovica; Moretti, Marta; Nicoletti, Carmine; Botta, Bruno; Ghirga, Francesca; Di Marcotullio, Lucia - 04f Poster
conference: Stratagem cost WG2 on Synthesis and nanodelivery strategies for new therapeutic tools against Multidrug Resistant Tumours (online)
book: Cost Action 17104(Stratagem) - ()

11573/1559760 - 2020 - Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold
Romeo, Isabella; Lospinoso Severini, Ludovica; Quaglio, Deborah; Basili, Irene; Ghirga, Francesca; Bufalieri, Francesca; Caimano, Miriam; Balducci, Silvia; Moretti, Marta; Loricchio, Elena; Maroder, Marella; Botta, Bruno; Mori, Mattia; Infante, Paola; Di Marcotullio, Lucia - 04f Poster
conference: STRATAGEM COST CA17104: New diagnostic and therapeutic tools against multidrug resistant tumors (virtual meeting - online mode)
book: Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold - ()

11573/1560331 - 2020 - Dubs activating the hedgehog signaling pathway: a promising therapeutic target in cancer
Bufalieri, Francesca; Lospinoso Severini, Ludovica; Caimano, Miriam; Infante, Paola; Di Marcotullio, Lucia - 01g Articolo di rassegna (Review)
paper: CANCERS (Basel : MDPI) pp. - - issn: 2072-6694 - wos: WOS:000549233900001 (6) - scopus: 2-s2.0-85086322190 (9)

11573/1560340 - 2020 - The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma
Lospinoso Severini, Ludovica; Ghirga, Francesca; Bufalieri, Francesca; Quaglio, Deborah; Infante, Paola; Di Marcotullio, Lucia - 01g Articolo di rassegna (Review)
paper: EXPERT OPINION ON THERAPEUTIC TARGETS (--London United Kingdom:Informa Healthcare -London : Ashley, 2002-.) pp. 1159-1181 - issn: 1472-8222 - wos: WOS:000573407600001 (12) - scopus: 2-s2.0-85091689870 (14)

11573/1560346 - 2020 - Dual smo/braf inhibition by flavonolignans from silybum marianum
Mori, Mattia; Bufalieri, Francesca; Di Marcotullio, Lucia; Botta, Bruno; Botta, Mauro - 01a Articolo in rivista
paper: ANTIOXIDANTS (Basel: MDPI) pp. - - issn: 2076-3921 - wos: WOS:000539284200027 (13) - scopus: 2-s2.0-85085060049 (12)

11573/1210601 - 2019 - Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation
Antonucci, Laura; Di Magno, Laura; D'amico, Davide; Manni, Simona; Serrao, Silvia Maria; Di Pastena, Fiorella; Bordone, Rosa; Yurtsever, Zuleyha Nihan; Caimano, Miriam; Petroni, Marialaura; Giorgi, Alessandra; Schinina', Maria Eugenia; Di Marcotullio, Lucia; De Smaele, Enrico; Checquolo, Saula; Capalbo, Carlo; Agostinelli, Enzo; Maroder, Marella; Coni, Sonia; Canettieri, Gianluca - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF ONCOLOGY (National Hellenic Research Foundation:48 Vas Constatinou Avenue, Athens 11635 Greece:011 30 1 7241505, Fax: 011 30 1 7241505Editore attuale:PROFESSOR D A SPANDIDOS, 1, S MERKOURI ST, EDITORIAL OFFICE,, ATHENS, GREECE, 116 35. Editore precedente:Editorial Academy of the International Journal of Oncology.) pp. 505-514 - issn: 1019-6439 - wos: WOS:000454923900009 (15) - scopus: 2-s2.0-85058877986 (13)

11573/1255617 - 2019 - P300/CBP-associated factor regulates transcription and function of isocitrate dehydrogenase 2 during muscle differentiation
Cencioni, Chiara; Di Marcotullio, Lucia; Botta, Bruno; Spallotta, Francesco - 01a Articolo in rivista
paper: THE FASEB JOURNAL (Federation of American Societies for Experimental Biology (FASEB):9650 Rockville Pike, Room L-2310:Bethesda, MD 20814:(800)433-2732, (301)530-7027, EMAIL: staff@dues.faseb.org, INTERNET: http://www.faseb.org, Fax: (301)571-5728, (301)530-7001) pp. 4107-4123 - issn: 0892-6638 - wos: WOS:000459794800081 (9) - scopus: 2-s2.0-85063423944 (8)

11573/1304369 - 2019 - ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP
Bufalieri, Francesca; Infante, Paola; Bernardi, Flavia; Caimano, Miriam; Romania, Paolo; Moretti, Marta; Lospinoso Severini, Ludovica; Di Magno, Laura; Bellavia, Diana; Capalbo, Carlo; De Smaele, Enrico; Canettieri, Gianluca; Peschiaroli, Angelo; Giannini, Giuseppe; Locatelli, Franco; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: NATURE COMMUNICATIONS (London: Nature Publishing Group) pp. 1-15 - issn: 2041-1723 - wos: WOS:000476877400003 (19) - scopus: 2-s2.0-85069646549 (19)

11573/1310873 - 2019 - Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains CRC progression and chemoresistance
Pelullo, Maria; Nardozza, Francesca; Zema, Sabrina; Quaranta, Roberta; Nicoletti, Carmine; Besharat, Zein Mersini; Felli, Maria Pia; Cerbelli, Bruna; D'amati, Giulia; Palermo, Rocco; Capalbo, Carlo; Talora, Claudio; Di Marcotullio, Lucia; Giannini, Giuseppe; Checquolo, Saula; Screpanti, Isabella; Bellavia, Diana - 01a Articolo in rivista
paper: CANCER RESEARCH (Philadelphia : American Association for Cancer Research) pp. 5575-5586 - issn: 1538-7445 - wos: WOS:000494363200013 (12) - scopus: 2-s2.0-85074445960 (15)

11573/1318627 - 2019 - Targeting hedgehog signalling through the ubiquitylation process: the multiple roles of the HECT-E3 ligase itch
Infante, Paola; Lospinoso Severini, Ludovica; Bernardi, Flavia; Bufalieri, Francesca; Di Marcotullio, Lucia - 01g Articolo di rassegna (Review)
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 98- - issn: 2073-4409 - wos: WOS:000460896000020 (12) - scopus: 2-s2.0-85073565486 (14)

11573/1321077 - 2019 - A Smo/Gli multitarget hedgehog pathway inhibitor impairs tumor growth
Lospinoso Severini, Ludovica; Quaglio, Deborah; Basili, Irene; Ghirga, Francesca; Bufalieri, Francesca; Caimano, Miriam; Balducci, Silvia; Moretti, Marta; Romeo, Isabella; Loricchio, Elena; Maroder, Marella; Botta, Bruno; Mori, Mattia; Infante, Paola; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: CANCERS (Basel : MDPI) pp. 1518-1534 - issn: 2072-6694 - wos: WOS:000498826000115 (21) - scopus: 2-s2.0-85073503434 (24)

11573/1338842 - 2019 - KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2
Spiombi, Eleonora; Angrisani, Annapaola; Fonte, Simone; De Feudis, Giuseppina; Fabretti, Francesca; Cucchi, Danilo; Izzo, Mariapaola; Infante, Paola; Miele, Evelina; Po, Agnese; Di Magno, Laura; Maroder, Marella; Canettieri, Gianluca; Giannini, Giuseppe; Ferretti, Elisabetta; Gulino, Alberto; Di Marcotullio, Lucia; Moretti, Marta; De Smaele, Enrico - 01a Articolo in rivista
paper: ONCOGENESIS (London Nature Publishing Group) pp. 64- - issn: 2157-9024 - wos: WOS:000494423700001 (10) - scopus: 2-s2.0-85074354238 (12)

11573/1347787 - 2019 - Discovery, characterization and potential roles of a novel NF-YAx splice variant in human neuroblastoma
Di Marcotullio, Lucia; Infante, Paola; Sebastiano, Manrico - 01a Articolo in rivista
paper: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. 482- - issn: 1756-9966 - wos: WOS:000515095500001 (7) - scopus: 2-s2.0-85076223386 (7)

11573/1347816 - 2019 - 1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma
D'alessandro, Giuseppina; Quaglio, Deborah; Lauro, Clotilde; Ghirga, Francesca; Ingallina, Cinzia; Fucile, Sergio; Porzia, Alessandra; Di Castro, Maria Amalia; Infante, Paola; Caliceti, Paolo; Di Marcotullio, Lucia; Botta, Bruno; Limatola, Cristina; Monaco, Lucia - 01a Articolo in rivista
paper: CELL COMMUNICATION AND SIGNALING (BioMed Central, London) pp. 108- - issn: 1478-811X - wos: WOS:000485121800001 (19) - scopus: 2-s2.0-85071619755 (22)

11573/1559753 - 2019 - Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold
Romeo, Isabella; Berardozzi, Simone; Bernardi, Flavia; Infante, Paola; Ingallina, Cinzia; Toscano, Sara; De Paolis, Elisa; Alfonsi, Romina; Caimano, Miriam; Botta, Bruno; Mori, Mattia; Di Marcotullio, Lucia; Ghirga, Francesca - 04f Poster
conference: XII EWDD - 12th European Workshop in Drug Design (Certosa di Pontignano, Siena (Italy))
book: Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold - ()

11573/1051225 - 2018 - Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61
Calcaterra, Andrea; Iovine, Valentina; Botta, Bruno; Quaglio, Deborah; D'acquarica, Ilaria; Ciogli, Alessia; Iazzetti, Antonia; Alfonsi, Romina; Lospinoso Severini, Ludovica; Infante, Paola; Di Marcotullio, Lucia; Ghirga, Francesca - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 349-358 - issn: 1475-6366 - wos: WOS:000423413000001 (33) - scopus: 2-s2.0-85041293877 (35)

11573/1085264 - 2018 - Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis
Infante, Paola; Faedda, Roberta; Bernardi, Flavia; Bufalieri, Francesca; Lospinoso Severini, Ludovica; Alfonsi, Romina; Mazza', Daniela; Coni, Sonia; Po, Agnese; Petroni, Marialaura; Ferretti, Elisabetta; Mori, Mattia; De Smaele, Enrico; Canettieri, Gianluca; Capalbo, Carlo; Maroder, Marella; Screpanti, Isabella; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: NATURE COMMUNICATIONS (London: Nature Publishing Group) pp. ...-... - issn: 2041-1723 - wos: WOS:000426899000002 (37) - scopus: 2-s2.0-85044632076 (37)

11573/1131161 - 2018 - Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold
Berardozzi, Simone; Bernardi, Flavia; Infante, Paola; Ingallina, Cinzia; Toscano, Sara; De Paolis, Elisa; Alfonsi, Romina; Caimano, Miriam; Botta, Bruno; Mori, Mattia; Di Marcotullio, Lucia; Ghirga, Francesca - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 554-562 - issn: 0223-5234 - wos: WOS:000443663200039 (21) - scopus: 2-s2.0-85049903501 (22)

11573/1206569 - 2018 - MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors
Petroni, Marialaura; Sardina, Francesca; Infante, Paola; Bartolazzi, Armando; Fabretti, Francesca; Di Giulio, Stefano; Capalbo, Carlo; Cardinali, Beatrice; Coppa, Anna; Colicchia, Valeria; Sahun Roncero, Maria; Belardinilli, Francesca; Di Marcotullio, Lucia; Gulino, Alberto; Giannini, Giuseppe - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. 895- - issn: 2041-4889 - wos: WOS:000444826200010 (28) - scopus: 2-s2.0-85052686149 (28)

11573/1024175 - 2017 - β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells
Miele, Evelina; Po, Agnese; Begalli, Federica; Antonucci, Laura; Cucchi, Danilo; Abballe, Luana; Besharat, Zein Mersini; Catanzaro, Giuseppina; Infante, Paola; Di Marcotullio, Lucia; Canettieri, Gianluca; De Smaele, Enrico; Screpanti, Isabella; Locatelli, Franco; Ferretti, Elisabetta - 01a Articolo in rivista
paper: BMC CANCER (BIOMED CENTRAL LTD, MIDDLESEX HOUSE, 34-42 CLEVELAND ST, LONDON, ENGLAND, W1T 4LB) pp. 488- - issn: 1471-2407 - wos: WOS:000405865300002 (40) - scopus: 2-s2.0-85024120271 (43)

11573/1085265 - 2017 - Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects
Lorefice, Elisa; Nuovo, Sara; Chiapparini, Luisa; Di Marcotullio, Lucia; Alfonsi, Romina; Bertini, Enrico; Valente, Enza Maria - 01a Articolo in rivista
paper: AMERICAN JOURNAL OF HUMAN GENETICS (University of Chicago Press:PO Box 37005, Journals Division:Chicago, IL 60637:(877)705-1878, (877)705-1878, (773)753-2247, EMAIL: subscriptions@press.uchicago.edu, INTERNET: http://www.press.uchicago.edu, Fax: (877)705-1879, (773)753-0811) pp. 552-563 - issn: 0002-9297 - wos: WOS:000412277300006 (25) - scopus: 2-s2.0-85030689010 (25)

11573/1560468 - 2017 - Targeting Gli acetylation in Shh-medulloblastoma: A successful preclinical approach
Coni, Sonia; Di Magno, Laura; Mancuso, Anna Barbara; Sdruscia, Giulia; Manni, Simona; Serrao, Silvia Maria; Di Marcotullio, Lucia; De Smaele, Enrico; Ferretti, Elisabetta; Canettieri, Gianluca - 01h Abstract in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (D. A. Spandidos. Athens) pp. S26-S26 - issn: 1107-3756 - wos: WOS:000411659300088 (0) - scopus: (0)

11573/1602341 - 2017 - Corrigendum: Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma
Coni, Sonia; Mancuso, Anna Barbara; Di Magno, Laura; Sdruscia, Giulia; Manni, Simona; Serrao, Silvia Maria; Rotili, Dante; Spiombi, Eleonora; Bufalieri, Francesca; Petroni, Marialaura; De Smaele, Enrico; Ferretti, Elisabetta; Capalbo, Carlo; Mai, Antonello; Screpanti, Isabella; Di Marcotullio, Lucia; Canettieri, Gianluca - 01b Commento, Erratum, Replica e simili
paper: SCIENTIFIC REPORTS (London : Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000399974300001 (5) - scopus: 2-s2.0-85068766477 (4)

11573/928720 - 2017 - Design, palladium-catalyzed synthesis, and biological investigation of 2-substituted 3-aroylquinolin-4(1H)-ones as inhibitors of the Hedgehog signaling pathway.
Alfonsi, Romina; Botta, Bruno; Cacchi, Sandro; Di Marcotullio, Lucia; Fabrizi, Giancarlo; Faedda, Roberta; Goggiamani, Antonella; Iazzetti, Antonia - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1469-1477 - issn: 0022-2623 - wos: WOS:000394924900016 (24) - scopus: 2-s2.0-85013768422 (24)

11573/946157 - 2017 - Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.
Coni, Sonia; Mancuso, Anna Barbara; Di Magno, Laura; Sdruscia, Giulia; Manni, Simona; Serrao, Silvia Maria; Rotili, Dante; Spiombi, Eleonora; Bufalieri, Francesca; Petroni, Marialaura; De Smaele, Enrico; Ferretti, Elisabetta; Capalbo, Carlo; Mai, Antonello; Screpanti, Isabella; Di Marcotullio, Lucia; Canettieri, Gianluca - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London : Nature Publishing Group) pp. 44079- - issn: 2045-2322 - wos: WOS:000396136700001 (45) - scopus: 2-s2.0-85014895304 (42)

11573/952694 - 2017 - Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma
Po, Agnese; Silvano, Marianna; Miele, Evelina; Capalbo, Carlo; Besharat, Zein Mersini; Catanzaro, Giuseppina; Cucchi, Danilo; Coni, Sonia; Di Marcotullio, Lucia; Canettieri, Gianluca; Vacca, Alessandra; De Smaele, Enrico; Screpanti, Isabella; Ferretti, Elisabetta - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. - - issn: 0950-9232 - wos: WOS:000407246200011 (62) - scopus: 2-s2.0-85016980676 (64)

11573/969457 - 2017 - Maml1 acts cooperatively with Gli proteins to regulate Sonic hedgheog signaling pathway
Quaranta, Roberta; Pelullo, Maria; Zema, Sabrina; Nardozza, Francesca; Checquolo, Saula; Lauer, Dieter Matthias; Bufalieri, Francesca; Palermo, Rocco; Felli, Maria Pia; Vacca, Alessandra; Talora, Claudio; Di Marcotullio, Lucia; Screpanti, Isabella; Bellavia, Diana - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000406870400031 (24) - scopus: 2-s2.0-85035040836 (23)

11573/863407 - 2016 - The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint
Di Magno, Laura; Basile, Alessio; Coni, Sonia; Manni, Simona; Sdruscia, Giulia; D'amico, Davide; Antonucci, Laura; Infante, Paola; De Smaele, Enrico; Cucchi, Danilo; Ferretti, Elisabetta; Di Marcotullio, Lucia; Screpanti, Isabella; Canettieri, Gianluca - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 9538-9549 - issn: 1949-2553 - wos: WOS:000375618100081 (34) - scopus: 2-s2.0-84961627529 (33)

11573/870335 - 2016 - MK-4101 - a potent inhibitor of the hedgehog pathway - is highly active against medulloblastoma and basal cell carcinoma
Pasquali, Emanuela; Alfonsi, Romina; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: MOLECULAR CANCER THERAPEUTICS (Philadelphia, PA : American Association for Cancer Research, c2001-) pp. - - issn: 1535-7163 - wos: WOS:000377427600003 (14) - scopus: 2-s2.0-84971500813 (14)

11573/901391 - 2016 - Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype
Infante, Paola; Alfonsi, Romina; Ingallina, Cinzia; Quaglio, Deborah; Ghirga, Francesca; D'acquarica, Ilaria; Bernardi, Flavia; Di Magno, Laura; Canettieri, Gianluca; Screpanti, Isabella; Gulino, Alberto; Botta, Bruno; Mori, Mattia; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000387968100003 (48) - scopus: 2-s2.0-84992361773 (47)

11573/901428 - 2016 - Nuclear Factor of Activated T Cells-dependent Down-regulation of the Transcription Factor Glioma-associated Protein 1 (GLI1) Underlies the Growth Inhibitory Properties of Arachidonic Acid
Botta, Bruno; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 1933-1947 - issn: 0021-9258 - wos: WOS:000368620700031 (13) - scopus: 2-s2.0-84959020431 (13)

11573/913369 - 2016 - SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development
Infante, Paola; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 1400-1416 - issn: 0261-4189 - wos: WOS:000378929900004 (39) - scopus: 2-s2.0-84977560736 (41)

11573/649688 - 2015 - Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors
Infante, Paola; Alfonsi, Romina; Ghirga, Francesca; Toscano, Sara; Ingallina, Cinzia; Cucchi, Danilo; Po, Agnese; Miele, Evelina; Canettieri, Gianluca; De Smaele, Enrico; Ferretti, Elisabetta; Screpanti, Isabella; Botta, Bruno; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 200-217 - issn: 0261-4189 - wos: WOS:000347878900008 (123) - scopus: 2-s2.0-84921293370 (127)

11573/783287 - 2015 - Cullin3-BTB interface: a novel target for stapled peptides
Di Marcotullio, Lucia - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. - - issn: 1932-6203 - wos: WOS:000352477800046 (21) - scopus: 2-s2.0-84928920026 (24)

11573/803852 - 2015 - The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress
Petroni, Marialaura; Sardina, Francesca; Heil, Constantin; Sahun Roncero, Maria; Colicchia, Valeria; Veschi, Veronica; Soriani, Alessandra; Di Marcotullio, Lucia; Screpanti, Isabella; Gulino, Alberto; Giannini, Giuseppe - 01a Articolo in rivista
paper: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 197-206 - issn: 1350-9047 - wos: WOS:000368062200002 (22) - scopus: 2-s2.0-84954076146 (25)

11573/808783 - 2015 - Non-canonical Hedgehog/ampk-mediated control of polyamine metabolism supports neuronal and medulloblastoma cell growth
D'amico, Davide; Di Magno, Laura; Coni, Sonia; Sdruscia, Giulia; Macone, Alberto; Miele, Evelina; Infante, Paola; Di Marcotullio, Lucia; De Smaele, Enrico; Ferretti, Elisabetta; Ciapponi, Laura; Giangaspero, Felice; Agostinelli, Enzo; Screpanti, Isabella; Gulino, Alberto; Canettieri, Gianluca - 01a Articolo in rivista
paper: DEVELOPMENTAL CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 21-35 - issn: 1534-5807 - wos: WOS:000363076000008 (46) - scopus: 2-s2.0-84945252145 (46)

11573/808871 - 2015 - Digging a hole under Hedgehog: Downstream inhibition as an emerging anticancer strategy
Di Magno, Laura; Coni, Sonia; Di Marcotullio, Lucia; Canettieri, Gianluca - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (Elsevier Scientific Publ. Co.) pp. 62-72 - issn: 0304-419X - wos: WOS:000360776200006 (49) - scopus: 2-s2.0-84934937938 (51)

11573/845844 - 2015 - New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer
La Regina, Giuseppe; Verrico, Annalisa; Coluccia, Antonio; Famiglini, Valeria; Pelliccia, Sveva; Passacantilli, Sara; Mazzoccoli, Carmela; Miele, Andrea; Monti, Ludovica; Nalli, Marianna; Alfonsi, Romina; Di Marcotullio, Lucia; Gulino, Alberto; Ricci, Biancamaria; Soriani, Alessandra; Santoni, Angela; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5789-5807 - issn: 0022-2623 - wos: WOS:000359683700008 (45) - scopus: 2-s2.0-84939138196 (44)

11573/871963 - 2015 - Targeting GLI factors to inhibit the Hedgehog pathway
Infante, Paola; Alfonsi, Romina; Botta, Bruno; Mori, Mattia; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: TRENDS IN PHARMACOLOGICAL SCIENCES (Elsevier Trends Journals:An Imprint of Elsevier Science Limited, The Boulevard, Langford Lane, Kidlington, Oxford 0X5 1GB United Kingdom:011 44 1865 843000, 011 44 1865 843699, Fax: 011 44 1865 843010) pp. 547-558 - issn: 0165-6147 - wos: WOS:000359879100009 (79) - scopus: 2-s2.0-84938953364 (80)

11573/871967 - 2015 - Insights into gli factors ubiquitylation methods
Infante, Paola; Alfonsi, Romina; Di Marcotullio, Lucia - 02a Capitolo o Articolo
book: Methods in Molecular Biology - (978-1-4939-2771-5; 978-1-4939-2772-2; 978-1-4939-2771-5; 978-1-4939-2772-2)

11573/543173 - 2014 - CNBP regulates wing development in Drosophila melanogaster by promoting IRES-dependent translation of dMyc
Antonucci, Laura; D'amico, Davide; Di Magno, Laura; Coni, Sonia; Di Marcotullio, Lucia; Gulino, Alberto; Ciapponi, Laura; Canettieri, Gianluca - 01a Articolo in rivista
paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 434-439 - issn: 1538-4101 - wos: WOS:000332833400019 (15) - scopus: 2-s2.0-84896873986 (16)

11573/648414 - 2014 - Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth
Di Magno, Laura; D'amico, Davide; Coni, Sonia; Macone, Alberto; Infante, Paola; Di Marcotullio, Lucia; De Smaele, Enrico; Ferretti, Elisabetta; Screpanti, Isabella; Agostinelli, Enzo; Gulino, Alberto; Canettieri, Gianluca - 01a Articolo in rivista
paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 3404-3413 - issn: 1538-4101 - wos: WOS:000348313100013 (30) - scopus: 2-s2.0-84915795126 (29)

11573/649690 - 2014 - Yin-Yang strands of PCAF/Hedgehog axis in cancer control
Infante, Paola; Canettieri, Gianluca; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: TRENDS IN MOLECULAR MEDICINE (London: Elsevier Science, 2001-) pp. 416-418 - issn: 1471-4914 - wos: WOS:000340303300002 (13) - scopus: 2-s2.0-84905115865 (12)

11573/649693 - 2014 - Numb-dependent integration of pre-TCR and p53 function in T-cell precursor development.
Checquolo, Saula; Del Gaudio, Francesca; Palermo, Rocco; Franciosa, Giulia; Di Marcotullio, Lucia; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. Article Number: e1472- - issn: 2041-4889 - wos: WOS:000344994000044 (5) - scopus: 2-s2.0-84925810051 (5)

11573/649699 - 2014 - New Pyrrole Derivatives with Potent Tubulin Polymerization Inhibiting Activity As Anticancer Agents Including Hedgehog-Dependent Cancer
La Regina, Giuseppe; Coluccia, Antonio; Famiglini, Valeria; Pelliccia, Sveva; Passacantilli, Sara; Miele, Andrea; Nalli, Marianna; Alfonsi, Romina; Di Marcotullio, Lucia; Gulino, Alberto; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6531-6552 - issn: 0022-2623 - wos: WOS:000340445900020 (59) - scopus: 2-s2.0-84906094556 (65)

11573/656612 - 2014 - Notch3/Jagged1 Circuitry Reinforces Notch Signaling and Sustains T-ALL.
Pelullo, Maria; Quaranta, Roberta; Talora, Claudio; Checquolo, Saula; Cialfi, Samantha; Felli, Maria Pia; Besharat, Zein Mersini; Palermo, Rocco; Di Marcotullio, Lucia; Gulino, Alberto; Screpanti, Isabella; Bellavia, Diana - 01a Articolo in rivista
paper: NEOPLASIA (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 1007-1017 - issn: 1522-8002 - wos: WOS:000347172100002 (37) - scopus: 2-s2.0-85003322506 (38)

11573/527250 - 2013 - PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress
Mazza, Daniele; Infante, Paola; Colicchia, Valeria; Greco, Azzura; Alfonsi, Romina; Antonucci, Laura; Po, Agnese; De Smaele, Enrico; Ferretti, Elisabetta; Capalbo, Carlo; Bellavia, Diana; Canettieri, Gianluca; Giannini, Giuseppe; Screpanti, Isabella; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 1688-1697 - issn: 1350-9047 - wos: WOS:000327010600012 (65) - scopus: 2-s2.0-84887619992 (70)

11573/527314 - 2013 - microRNA-17-92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1
Garg, Neha; Po, Agnese; Miele, Evelina; Campese, Antonio Francesco; Begalli, Federica; Infante, Paola; Capalbo, Carlo; De Smaele, Enrico; Canettieri, Gianluca; Di Marcotullio, Lucia; Screpanti, Isabella; Ferretti, Elisabetta; Gulino, Alberto - 01a Articolo in rivista
paper: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 2819-2832 - issn: 0261-4189 - wos: WOS:000326504900006 (53) - scopus: 2-s2.0-84887046837 (52)

11573/543166 - 2013 - Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy
Coni, Sonia; Antonucci, Laura; D'amico, Davide; Di Magno, Laura; Infante, Paola; De Smaele, Enrico; Giannini, Giuseppe; Di Marcotullio, Lucia; Screpanti, Isabella; Gulino, Alberto; Canettieri, Gianluca - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e65718- - issn: 1932-6203 - wos: WOS:000321099000097 (54) - scopus: 2-s2.0-84878804952 (56)

11573/444530 - 2012 - Hedgehog/Gli Control by Ubiquitination/Acetylation Interplay
Gulino, Alberto; Di Marcotullio, Lucia; Canettieri, Gianluca; De Smaele, Enrico; Screpanti, Isabella - 02a Capitolo o Articolo
book: Hedgehog Signaling - (9780123946225)

11573/360864 - 2011 - Protected from the inside: Endogenous histone deacetylase inhibitors and the road to cancer
Di Marcotullio, Lucia; Canettieri, Gianluca; Infante, Paola; Greco, Azzura; Gulino, Alberto - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (Elsevier Scientific Publ. Co.) pp. 241-252 - issn: 0304-419X - wos: WOS:000289020200009 (41) - scopus: 2-s2.0-79951713773 (44)

11573/377914 - 2011 - Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma
De Smaele, Enrico; Di Marcotullio, Lucia; Moretti, Marta; Pelloni, Marianna; Occhione, Maria Anna; Infante, Paola; Cucchi, Danilo; Greco, Azzura; Pietrosanti, Laura; Coni, Sonia; Canettieri, Gianluca; Ferretti, Elisabetta; Maroder, Marella; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: NEOPLASIA (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 374-385 - issn: 1522-8002 - wos: WOS:000289529400009 (66) - scopus: 2-s2.0-79952438480 (67)

11573/377915 - 2011 - Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal
Di Marcotullio, Lucia; Greco, Azzura; Mazza', Daniela; Canettieri, Gianluca; Pietrosanti, Laura; Infante, Paola; Coni, Sonia; Moretti, Marta; De Smaele, Enrico; Ferretti, Elisabetta; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 65-76 - issn: 0950-9232 - wos: WOS:000285959300006 (82) - scopus: 2-s2.0-78650983824 (84)

11573/377916 - 2011 - Molecular organization of the cullin E3 ligase adaptor KCTD11
Di Marcotullio, Lucia; De Smaele, Enrico; Greco, Azzura; Mazza', Daniela; Moretti, Marta; Gulino, Alberto - 01a Articolo in rivista
paper: BIOCHIMIE (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 715-724 - issn: 0300-9084 - wos: WOS:000289182400009 (43) - scopus: 2-s2.0-79952438310 (43)

11573/229541 - 2010 - Turning off the switch in medulloblastoma. The inhibitory acetylation of an oncogene
Canettieri, Gianluca; Di Marcotullio, Lucia; Coni, Sonia; Greco, Azzura; Gulino, Alberto - 01m Editorial/Introduzione in rivista
paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 2047-2048 - issn: 1538-4101 - wos: WOS:000279148400003 (7) - scopus: 2-s2.0-77953598291 (6)

11573/364193 - 2010 - Hedgehog controls neural stem cells through p53-independent regulation of Nanog
Po, Agnese; Ferretti, Elisabetta; Miele, Evelina; De Smaele, Enrico; Canettieri, Gianluca; Coni, Sonia; Di Marcotullio, Lucia; Biffoni, Marco; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 2646-2658 - issn: 0261-4189 - wos: WOS:000280658900017 (170) - scopus: 2-s2.0-77955362243 (175)

11573/401408 - 2010 - Histone deacetylase and Cullin3-REN KCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation
Canettieri, Gianluca; Di Marcotullio, Lucia; Greco, Azzura; Coni, Sonia; Antonucci, Laura; Infante, Paola; Pietrosanti, Laura; De Smaele, Enrico; Ferretti, Elisabetta; Miele, Evelina; Pelloni, Marianna; Giorgi, Alessandra; Schinina', Maria Eugenia; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: NATURE CELL BIOLOGY (Nature America Incorporated:345 Park Avenue South, 6th Floor:New York, NY 10010:(888)331-6288, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: (212)689-9108) pp. 132-U91 - issn: 1465-7392 - wos: WOS:000274139400007 (250) - scopus: 2-s2.0-75949106376 (253)

11573/132957 - 2009 - The multiple functions of Numb.
Gulino, Alberto; Di Marcotullio, Lucia; Screpanti, Isabella - 01a Articolo in rivista
paper: EXPERIMENTAL CELL RESEARCH (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 900-906 - issn: 0014-4827 - wos: WOS:000275986000002 (146) - scopus: 2-s2.0-77649183954 (156)

11573/224364 - 2009 - MicroRNA profiling in human medulloblastoma
Ferretti, Elisabetta; De Smaele, Enrico; Po, Agnese; Di Marcotullio, Lucia; Giangaspero, Felice; Farcomeni, Alessio; Nofroni, Italo; Bozzoni, Irene; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF CANCER (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 568-577 - issn: 0020-7136 - wos: WOS:000262205400009 (248) - scopus: 2-s2.0-58149279841 (257)

11573/359122 - 2008 - Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells
Ferretti, Elisabetta; De Smaele, Enrico; Miele, Evelina; Po, Agnese; Pelloni, Marianna; Di Marcotullio, Lucia; Screpanti, Isabella; Bozzoni, Irene; Gulino, Alberto - 01a Articolo in rivista
paper: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 2616-2627 - issn: 0261-4189 - wos: WOS:000259891300014 (254) - scopus: 2-s2.0-53549129980 (269)

11573/362261 - 2008 - An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma
De Smaele, Enrico; Ferretti, Elisabetta; Pelloni, Marianna; Po, Agnese; Canettieri, Gianluca; Coni, Sonia; Di Marcotullio, Lucia; Greco, Azzura; Moretti, Marta; Maroder, Marella; Screpanti, Isabella; Giannini, Giuseppe; Gulino, Alberto - 01a Articolo in rivista
paper: NEOPLASIA (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 89-98 - issn: 1522-8002 - wos: WOS:000253614300009 (42) - scopus: 2-s2.0-38649132910 (42)

11573/239202 - 2007 - Hedgehog signaling pathway in neural development and disease
Gulino, Alberto; Di Marcotullio, Lucia; Ferretti, Elisabetta; De Smaele, Enrico; Screpanti, Isabella - 01a Articolo in rivista
paper: PSYCHONEUROENDOCRINOLOGY (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. S52-S56 - issn: 0306-4530 - wos: WOS:000249718600011 (29) - scopus: 2-s2.0-34547656204 (31)
conference: Lille Summer School in Neuroscience (Lille, FRANCE)

11573/358524 - 2007 - The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells
Di Marcotullio, Lucia; Gioia, Ubaldo; Ferretti, Elisabetta; Gulino, Alberto; Bozzoni, Irene - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 7957-7962 - issn: 0027-8424 - wos: WOS:000246461500042 (113) - scopus: 2-s2.0-34249946434 (125)

11573/360501 - 2007 - Multiple ubiquitin-dependent processing pathways regulate hedgehog/gli signaling: implications for cell development and tumorigenesis.
Di Marcotullio, Lucia; Ferretti, Elisabetta; Greco, Azzura; De Smaele, Enrico; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 390-393 - issn: 1538-4101 - wos: WOS:000245495600002 (30) - scopus: 2-s2.0-33847769746 (29)

11573/364518 - 2007 - The E3 ligase Aip4/Itch ubiquitinates and targets ErbB-4 for degradation
Santangelo, Laura; Belleudi, Francesca; Di Marcotullio, Lucia; Frati, Luigi; Torrisi, Maria Rosaria; Gulino, Alberto; Alimandi, Maurizio - 01a Articolo in rivista
paper: THE FASEB JOURNAL (Federation of American Societies for Experimental Biology (FASEB):9650 Rockville Pike, Room L-2310:Bethesda, MD 20814:(800)433-2732, (301)530-7027, EMAIL: staff@dues.faseb.org, INTERNET: http://www.faseb.org, Fax: (301)571-5728, (301)530-7001) pp. 2849-2862 - issn: 0892-6638 - wos: WOS:000249237500026 (61) - scopus: 2-s2.0-34548501531 (64)

11573/234575 - 2006 - Suppressors of Hedgehog signalling: linking aberrant development of neural progenitors to tumorigenesis.
Di Marcotullio, Lucia; Ferretti, Elisabetta; De Smaele, Enrico; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: MOLECULAR NEUROBIOLOGY (Humana Press Incorporated:999 Riverview Drive, Suite 208:Totowa, NJ 07512:(973)256-1699, EMAIL: lglasner@humanapr.com, INTERNET: http://www.humanapress.com, Fax: (973)256-8341) pp. 193-204 - issn: 0893-7648 - wos: WOS:000250119900004 (17) - scopus: 2-s2.0-33847084412 (22)

11573/362834 - 2006 - Alternative splicing of the ErbB-4 cytoplasmic domain and its regulation by hedgehog signaling identify distinct medulloblastoma subsets
Ferretti, Elisabetta; Di Marcotullio, Lucia; Greco, Azzura; Po, Agnese; De Smaele, Enrico; Giangaspero, Felice; Maroder, Marella; Alimandi, Maurizio; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 7267-7273 - issn: 0950-9232 - wos: WOS:000242244700005 (39) - scopus: 2-s2.0-33751307615 (38)

11573/364857 - 2006 - Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch- dependent ubiquitination
Di Marcotullio, Lucia; Ferretti, Elisabetta; Greco, Azzura; De Smaele, Enrico; Po, Agnese; Alimandi, Maurizio; Giannini, Giuseppe; Maroder, Marella; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: NATURE CELL BIOLOGY (Nature America Incorporated:345 Park Avenue South, 6th Floor:New York, NY 10010:(888)331-6288, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: (212)689-9108) pp. 1415-U68 - issn: 1465-7392 - wos: WOS:000242419800018 (225) - scopus: 2-s2.0-33751503224 (229)

11573/231246 - 2005 - Hedgehog checkpoints in medulloblastoma: the chromosome 17p-deletion paradigm.
Ferretti, Elisabetta; De Smaele, Enrico; Di Marcotullio, Lucia; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: TRENDS IN MOLECULAR MEDICINE (London: Elsevier Science, 2001-) pp. 537-545 - issn: 1471-4914 - wos: WOS:000234320800004 (57) - scopus: 2-s2.0-28244467388 (60)

11573/431889 - 2005 - Hedgehog antagonist REN(KCTD11) regulates proliferation and apoptosis of developing granule cell progenitors.
Argenti, Beatrice; Di Marcotullio, Lucia; Ferretti, Elisabetta; Napolitano, Maddalena; Canterini, Sonia; De Smaele, Enrico; Greco, Azzura; Fiorenza, Maria Teresa; Maroder, Marella; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: THE JOURNAL OF NEUROSCIENCE (Society for Neuroscience:11 Dupont Circle, Suite 500:Washington, DC 20036:(202)462-6688, EMAIL: membership@sfn.org, subs@sfn.org, INTERNET: http://www.sfn.org, Fax: (202)462-1547) pp. 8338-8346 - issn: 0270-6474 - wos: WOS:000231718600024 (60) - scopus: 2-s2.0-24744446807 (61)

11573/232498 - 2004 - Chromosome 17p Deletion in Human Medulloblastoma: A Missing Checkpoint in the Hedgehog Pathway
De Smaele, Enrico; Di Marcotullio, Lucia; Ferretti, Elisabetta; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 1263-1266 - issn: 1538-4101 - wos: WOS:000225590800015 (32) - scopus: 2-s2.0-13944275921 (31)

11573/233088 - 2004 - REN KCTD11 is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma.
Di Marcotullio, Lucia; Ferretti, Elisabetta; De Smaele, Enrico; Masuelli, Laura; Napolitano, Maddalena; Maroder, Marella; Giangaspero, Felice; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 10833-10838 - issn: 0027-8424 - wos: WOS:000222842700062 (151) - scopus: 2-s2.0-3242722919 (158)

11573/365265 - 2004 - HMGA molecules in neuroblastic tumors
Massimi, Isabella; Di Marcotullio, Lucia; Gulino, Alberto; Giannini, Giuseppe - 01a Articolo in rivista
paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (New York: New York Academy of Sciences) pp. 122-132 - issn: 0077-8923 - wos: WOS:000228127300012 (17) - scopus: 2-s2.0-14944361858 (17)
conference: Conference on Signal Transduction and Communication in Cancer Cells (Erice, ITALY)

11573/256037 - 2003 - EGF- and cell-cycle-regulated STAG1/PMEPA1 ERG1.2 belongs to a conserved gene family and is overexpressed and amplified in breast and ovarian cancer
Giannini, Giuseppe; Di Marcotullio, Lucia; Zani, Massimo; Screpanti, Isabella; Frati, Luigi; Gulino, Alberto - 01a Articolo in rivista
paper: MOLECULAR CARCINOGENESIS (editore attuale: WILEY-LISS, DIV JOHN WILEY & SONS INC, 111 RIVER ST, HOBOKEN, USA, NJ, 07030. editore precedente: New York, NY : Wiley-Liss.) pp. 188-200 - issn: 0899-1987 - wos: WOS:000187078000005 (52) - scopus: 2-s2.0-0346243789 (60)

11573/132057 - 2002 - Oncogenic role of the ubiquitin ligase subunit Skp2 in human cancer
Di Marcotullio, Lucia - 01a Articolo in rivista
paper: THE JOURNAL OF CLINICAL INVESTIGATION (American Society for Clinical Investigation:PO Box 7226:Ann Arbor, MI 48107:(734)222-6050, EMAIL: rhickman@the-jci.org, INTERNET: http://www.jci.org, Fax: (734)222-6058) pp. 633-641 - issn: 0021-9738 - wos: (0) - scopus: 2-s2.0-0036733716 (255)

11573/132355 - 2001 - P27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis
Di Marcotullio, Lucia - 01a Articolo in rivista
paper: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 6672-6682 - issn: 0261-4189 - wos: WOS:000172629100012 (249) - scopus: 2-s2.0-0035803593 (250)

11573/250458 - 2001 - EGF regulates a complex pattern of gene expression and represses smooth muscle differentiation during the neurotypic conversion of the neural-crest-derived TC-1S cell line
Giannini, Giuseppe; Di Marcotullio, Lucia; Zani, Massimo; Frati, Luigi; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: EXPERIMENTAL CELL RESEARCH (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 353-362 - issn: 0014-4827 - wos: WOS:000167845100017 (7) - scopus: 2-s2.0-0035298102 (7)

11573/250399 - 2000 - Expression of the HMGI(Y) gene products in human neuroblastic tumors correlates with differentiation status
Giannini, Giuseppe; Di Marcotullio, Lucia; Zani, Massimo; Frati, Luigi; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: BRITISH JOURNAL OF CANCER (Editore attuale:NATURE PUBLISHING GROUP, MACMILLAN BUILDING, 4 CRINAN ST, LONDON, ENGLAND, N1 9XW Harcourt Publishers Limited:Foots Cray High Street, Sidcup Kent DA14 5HP United Kingdom:011 44 20 83085700, EMAIL: journals@harcourt.com, INTERNET: http://www.harcourt-international.com, Fax: 011 44 20 83085876) pp. 1503-1509 - issn: 0007-0920 - wos: WOS:000165603000017 (38) - scopus: 2-s2.0-0033665982 (41)

11573/241983 - 1999 - HMGI(Y) and HMGI-C genes are expressed in neuroblastoma cell lines and tumors and affect retinoic acid responsiveness
Giannini, Giuseppe; Di Marcotullio, Lucia; Zani, Massimo; Scarpa, Susanna; Vacca, Alessandra; Screpanti, Isabella; Frati, Luigi; Gulino, Alberto - 01a Articolo in rivista
paper: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 2484-2492 - issn: 0008-5472 - wos: WOS:000080410200039 (36) - scopus: 2-s2.0-0033563255 (37)

11573/242153 - 1999 - Thrombospondin-1 is a mediator of the neurotypic differentiation induced by EGF in thymic epithelial cells
Vacca, Alessandra; Di Marcotullio, Lucia; Giannini, Giuseppe; Scarpa, Susanna; Stoppacciaro, Antonella; Maroder, Marella; Frati, Luigi; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: EXPERIMENTAL CELL RESEARCH (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 79-86 - issn: 0014-4827 - wos: WOS:000079935100009 (15) - scopus: 2-s2.0-0033541420 (15)

11573/245918 - 1999 - Modulation of gene expression following long-term synaptic depression in the striatum
Napolitano, Maddalena; Vacca, Alessandra; Bellavia, Diana; Di Marcotullio, Lucia; Frati, Luigi; Gulino, Alberto - 01a Articolo in rivista
paper: MOLECULAR BRAIN RESEARCH (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 89-96 - issn: 0169-328X - wos: WOS:000082766900009 (23) - scopus: 2-s2.0-0032863943 (24)

11573/244858 - 1998 - Changing nucleosome positions in vivo through modification of the DNA rotational information
Di Marcotullio, Lucia; Buttinelli, Memmo; Di Mauro, Ernesto; Negri, Rodolfo - 01a Articolo in rivista
paper: BIOCHEMICAL JOURNAL (Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331) pp. 65-69 - issn: 0264-6021 - wos: WOS:000074893500010 (2) - scopus: 2-s2.0-0032127164 (3)

11573/246203 - 1998 - The growth arrest and downregulation of c-myc transcription induced by ceramide are related events dependent on p21 induction, Rb underphosphorylation and E2F sequestering.
Giannini, Giuseppe; Di Marcotullio, Lucia; Gulino, Alberto - 01a Articolo in rivista
paper: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 381-389 - issn: 1350-9047 - wos: WOS:000073615800006 (45) - scopus: (0)

11573/246110 - 1997 - 2-Aminopurine unravels a role for pRB in the regulation of gene expression by transforming growth factor beta.
Giannini, Giuseppe; Di Marcotullio, Lucia; Zani, Massimo; Screpanti, Isabella; Frati, Luigi; Gulino, Alberto - 01a Articolo in rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 5313-5319 - issn: 0021-9258 - wos: WOS:A1997WJ85500093 (7) - scopus: 2-s2.0-15144356448 (7)

11573/131927 - 1995 - Changing nucleosome positions through modification of the DNA rotational information
Buttinelli, Memmo; Negri, Rodolfo; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (Editore National Academy of Sciences a Washington, DC) pp. 10747-10751 - issn: 1091-6490 - wos: WOS:A1995TD89000062 (11) - scopus: 2-s2.0-0028809559 (10)

11573/246046 - 1995 - Changing nucleosome positions through the modification of the DNA rotational information.
Buttinelli, Memmo; Negri, Rodolfo; Di Marcotullio, Lucia; Di Mauro, Ernesto - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 10747-10751 - issn: 0027-8424 - wos: (0) - scopus: (0)

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