CHIARA LONGO

Dottoressa di ricerca

ciclo: XXXVI


supervisore: Prof.ssa Paola Vittorioso
co-supervisore: Prof.ssa Roberta Costi

Titolo della tesi: PRC2 role in plant cold response

Plants have evolved adaptive strategies to survive freezing temperatures during winter. Cold acclimation involves extensive reprogramming of gene expression dependent on CBF transcription factors that activate downstream cold-responsive (COR) genes. Recent evidence indicates that epigenetic mechanisms also regulate cold acclimation, but their roles are not fully understood. This thesis examined the involvement of Polycomb Repressive Complex 2 (PRC2) in cold acclimation. Mutants lacking PRC2 components showed altered freezing tolerance phenotypes, suggesting PRC2 controls cold-regulated genes. Transcriptome analysis of clf mutant during cold treatment, revealed different cold stress response pathways by PRC2 regulated. Collectively, results indicate that PRC2 mediates genome-wide transcriptional regulation of cold-responsive genes. This thesis provides new insights into PRC2 versatile functions in plant adaptation to cold stress.

Produzione scientifica

11573/1678807 - 2023 - Plants and Small Molecules: An Up-and-Coming Synergy
Lepri, A.; Longo, C.; Messore, A.; Kazmi, H.; Madia, V. N.; Di Santo, R.; Costi, R.; Vittorioso, P. - 01g Articolo di rassegna (Review)
rivista: PLANTS (Basel: MDPI) pp. - - issn: 2223-7747 - wos: WOS:000977210900001 (2) - scopus: 2-s2.0-85156214656 (2)

11573/1654141 - 2022 - New Inhibitors of the human p300/CBP acetyltransferase are selectively active against the Arabidopsis HAC proteins
Longo, Chiara; Lepri, Andrea; Paciolla, Andrea; Messore, Antonella; De Vita, Daniela; Bonaccorsi Di Patti, Maria Carmela; Amadei, Matteo; Madia, Valentina Noemi; Ialongo, Davide; Di Santo, Roberto; Costi, Roberta; Vittorioso, Paola - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-18 - issn: 1422-0067 - wos: WOS:000859422800001 (3) - scopus: 2-s2.0-85138734584 (3)

11573/1486911 - 2021 - From the outside to the inside: New insights on the main factors that guide seed dormancy and germination
Longo, C.; Holness, S.; De Angelis, V.; Lepri, A.; Occhigrossi, S.; Ruta, V.; Vittorioso, P. - 01g Articolo di rassegna (Review)
rivista: GENES (Basel : Molecular Diversity Preservation International) pp. 1-17 - issn: 2073-4425 - wos: WOS:000611020000001 (19) - scopus: 2-s2.0-85098788506 (19)

11573/1366728 - 2020 - The DOF Transcription Factors in Seed and Seedling Development
Ruta, Veronica; Longo, Chiara; Lepri, Andrea; De Angelis, Veronica; Occhigrossi, Sara; Costantino, Paolo; Vittorioso, Paola - 01g Articolo di rassegna (Review)
rivista: PLANTS (Basel: MDPI) pp. - - issn: 2223-7747 - wos: WOS:000519248200157 (36) - scopus: 2-s2.0-85079481201 (38)

11573/1321741 - 2019 - Inhibition of Polycomb Repressive Complex2 activity reduces trimethylation of H3K27 and affects development in Arabidopsis seedlings
Ruta, Veronica; Longo, Chiara; Boccaccini, Alessandra; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; Di Santo, Roberto; Lorrai, Riccardo; Dello Ioio, Raffaele; Sabatini, Sabrina; Costi, Roberta; Costantino, Paolo; Vittorioso, Paola - 01a Articolo in rivista
rivista: BMC PLANT BIOLOGY (London: BioMed Central.MIDDLESEX HOUSE, 34-42 CLEVELAND ST, LONDON, ENGLAND, W1T 4LB) pp. - - issn: 1471-2229 - wos: WOS:000490716900003 (12) - scopus: 2-s2.0-85073428390 (12)

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