LIDIA GIULIANI

PhD Student

PhD program:: XL
email: lidia.giuliani@uniroma1.it
phone: 3314973435
building: Dipartimento di Chimica e Tecnologie del Farmaco - CU019
room: 251 - 2° piano

supervisor: Prof. Rino Ragno
advisor: Prof. Rino Ragno

WORK EXPERIENCE - (November 2024) PhD in Pharmaceutical Sciences, cycle XL, at Sapienza University of Rome, Department of Medicinal Chemistry and Technology. - (February 2024) Research fellowship at the Department of Biochemical Sciences A. Rossi Fanelli at Sapienza University of Rome for a project entitled: Application of Ligand-Based and Structure-Based methods to develop new MMP-9 inhibitors. - (February 2021- October 2023) Experimental thesis in Computational Medicinal Chemistry entitled: Molecular docking as a structure-based method for the design of bioactive molecules: comparison of the effectiveness of different programmes applied to a series of 60 protein families. TRAINING - (October 2017 - October 2023) Degree in Pharmaceutical Chemistry and Technology at Sapienza University of Rome. TECHNICAL SKILLS - Use of the Python language - Machine Learning - Molecular Docking - 3-D QSAR model generation

Research products

11573/1760293 - 2026 - Hesperetin’s antigenotoxicity: the impact on EMS-made lesions within Drosophila melanogaster somatic cells’ DNA, disclosed through molecular modeling

Matić, Sanja Lj.; Tomašević, Nevena; Božović, Mijat; Astolfi, Roberta; Giuliani, Lidia; Ragno, Rino; Mladenović, Milan - 01a Articolo in rivista

paper: PHYTOMEDICINE (-Jena,Germany: Elsevier -Jena,Germany: Urban & Fischer Verlag Jena) pp. - - issn: 0944-7113 - wos: WOS:001657912100001 (0) - scopus: 2-s2.0-105026167399 (0)

11573/1755830 - 2025 - Discovery of first-in-class carbonic anhydrase/histone deacetylase dual inhibitors with antiproliferative activity in cancer cells

Bozdag, Murat; Mroweh, Nabil; Raucci, Alessia; Angeli, Andrea; Peppicelli, Silvia; Biagioni, Alessio; Calorini, Lido; Trisciuoglio, Daniela; Ragno, Rino; Astolfi, Roberta; Giuliani, Lidia; Zwergel, Clemens; Valente, Sergio; Andreucci, Elena; Carta, Fabrizio; Mai, Antonello; Supuran, Claudiu T - 01a Articolo in rivista

paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 22874-22895 - issn: 0022-2623 - wos: WOS:001603057800001 (1) - scopus: 2-s2.0-105021670189 (1)

11573/1760300 - 2025 - Identification of a novel minor-groove DNA binder that represses mitochondrial gene expression and induces apoptosis in highly aggressive leiomyosarcoma cells

Malavasi, Eleonora; Picco, Raffaella; Mallavarapu, Showmeya; Minisini, Martina; D’Este, Francesca; Bertozzo, Alessio; Giuliani, Lidia; Astolfi, Roberta; Chinellato, Monica; Bettin, Giacomo; Bortoluzzi, Marco; Ragno, Rino; Angelini, Alessandro; Brancolini, Claudio - 01a Articolo in rivista

paper: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. - - issn: 2058-7716 - wos: WOS:001611567500010 (0) - scopus: 2-s2.0-105021413040 (0)

11573/1743103 - 2025 - 1,2,4-Oxadiazoles in medicinal chemistry: trends of the last years

Cherkasova, Anastasia; Astolfi, Roberta; Nawrozkij, Maxim; Gladkikh, Boris; Proia, Eleonora; Giuliani, Lidia; Rotili, Dante; Ragno, Rino; Ivanov, Roman - 01a Articolo in rivista

paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ([Paris] : Elsevier, [198?]-) pp. 1-33 - issn: 1768-3254 - wos: WOS:001543360400001 (7) - scopus: 2-s2.0-105010209952 (6)