Research: Drug delivery in anti cancer therapy
WORK ADDRESS: Molecular Medicine Department, "La Sapienza" University, Viale Regina Elena 291, 00161 Rome, Italy (Nov 2020 - present)
SUPERVISOR: Prof. Gianluca Canettieri
PREVIOUS RESEARCH EXPERIENCE: Lab fellowship at Antidoping Laboratory F.M.S.I. Rome, Italy (May 2019- October 2020).
Research project "Genetic polymorphisms and antidoping analysis: towords the athlete's biological passport expansion". Cytotoxic analysis on in vitro models (HepG2, CaCo2), delivery of human growth hormone (GH) in macrophages models (Raw 264.7 cell line) and evaluation of cytotoxicity by MTS assay. Study of GH-IGF-1 axis polymorphisms in human serum and whole blood by ELISA. Supervisors of the study: Prof. Francesco Botrè and Francesco Donati, PhD.
Posters: https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.2020.34.s1.03980
https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.2020.34.s1.04017
Erasmus + Traineeship at OCDEM (Oxford Centre for Diabetes, Metabolism and Endocrinology), University of Oxford, UK (April 2018- July 2018). Evaluation of incretins (GLP-1, PYY) effects on insulin release from Langerhans Islets isolated from murine models and in vitro models (INS-1) by ELISA and RIA. Study performed under the supervision of Claudia Guida, PhD.
Erasmus + for Master's thesis at Pharmacology Laboratory of San Pablo CEU University, Madrid, Spain (February 2017 - July 2017). Thesis title "Effect of a high fat diet on memory process in a murine model of obesity". Evaluation of the effects of HFD (high fat diet) on glutamate pathway by behavioral tests (Y-maze), RT-PCR and Western Blotting on hippocampal and pre-frontal cortex from mouse models of obesity. Research activity was under the supervision of Prof. Mariano Ruiz Gayo and Adrian Plaza de la Fuente, PhD.
Attendee at Conference "FarMadrid - 26"
Bachelor's Thesis at Policlinico Gemelli, Pharmacology Laboratory (February - October 2015). Thesis title " Therapeutic drug monitoring and antiretroviral drugs", under the supervision of Prof. Pierluigi Navarra and Lucia Lisi, PhD.
Antiretroviral drugs monitoring by UPLC (Ultra performance liquid cromatography) and mass spectrometry in plasma samples of HIV + patiens.
CARREER:
Phd Student at the Department of Molecular Medicine, "La Sapienza" University (November 2020- present)
Esame di Stato Biologo (July 2020)
Master's Degree in Medical Biotechnology at "La Sapienza" University, 110/110 cum laude. (a.y. 2017/2018)
Bachelor's Degree in Healthcare Biotechnology at "Università Cattolica del Sacro Cuore", 108/110 (a.y. 2014/2015)
Scientific diploma at "Liceo Scientifico I. Newton", 80/100 (July 2010).
SKILLS: cell cultures, in vitro assays, molecular biology techniques (RT-PCR, Western Blotting), statistical analysis.