JACOPO DESIDERIO

Dottore di ricerca

ciclo: XXXIV

supervisore: Prof. Vito D'Andrea

Titolo della tesi: Linfoadenectomia guidata dall’imaging a fluorescenza mediante verde di indocianina e tecnologia near infrared nella gastrectomia robotica

Objectives: The objective of this study was verifying the feasibility and the role of a lymphadenectomy assisted by fluorescence imaging during robotic gastrectomy. Methods: This is an interventional prospective study. Inclusion criteria: cT1-cT3 and cN0-N+. Description: the day before surgery, the ICG was injected endoscopically into the submucosa around the tumor (0.83mg / mL, 0.3mL x 4-6). Each patient underwent a robotic total D2 gastrectomy. The lymph node stations were sent to the pathologist in different containers and further subdivided according to fluorescence. Results: Twenty patients were included in this study (Female=65%; mean age=73±9.56y). Among the pathological findings: mean tumor size=41.4mm±28.03; EGC was found in 45% of cases; 45% of patients had no Lns metastases (N0, no.=9), 20% had up to 2 metastic Lns (N1, no.=4), 5% 3 to 6 metastic Lns (N2, no.=1) and 30% a significant lymphnode spread with more than 7 metastatic Lns (N3a, no.=3; N3b no.=3). The 60% of patients showed an advanced stage of disease (II-III). No intraoperative major complications occurred. The total operative time was 324.61min±80.85, the EBL=103ml±102.83. The fluorescence detection rate was 100%. The total number of Lns analyzed was 1522Lns with a mean per patient=76.1Lns±25.41. The number of positive Lns for metastasis was 115Lns (mean=5.75Lns±9.11), consequently 1407Lns were free from disease. Total perigastric Lns=1155 (75.88%), while total extra-perigastric Lns=355 (24.12%). In the fluorescent tissue, 1349Lns were identified (88.63%). All the 115 metastatic Lns were fluorescent, while all Lns found in the non-fluorescent tissue areas were free from disease. Conclusions: Some advantages were found: easier detection of nodes in the adipose tissue and dissection in challenging anatomical sites, detection of small Lns that may escape at the normal view, checking the completeness of the lymphadenectomy at the end of the procedure.

Produzione scientifica

11573/1671405 - 2023 - THE DUODENAL WINDOW APPROACH TO PANCREATODUODENECTOMY

Tebala, G. D.; Avenia, S.; Desiderio, J.; Di Nardo, D.; Gemini, A.; Ranucci, M. C.; Trastulli, S.; Cirocchi, R. - 01a Articolo in rivista

rivista: JOURNAL OF AMERICAN COLLEGE HEALTH (Heldref Publications:1319 Eighteenth Street Northwest:Washington, DC 20036:(800)365-9753, (202)296-6267, EMAIL: subscriptions@heldref.org, INTERNET: http://www.heldref.org, Fax: (202)293-6130) pp. - - issn: 0744-8481 - wos: (0) - scopus: (0)

11573/1671408 - 2022 - Incidental Neuroendocrine Tumor of the appendix: what better attitude in case of acute appendicitis? A case report and review of literature.

Di Nardo, Domenico; Desiderio, J.; Trastulli, S.; Gemini, A.; Boccolini, A.; Di Cintio, A.; Ricci, F.; Mazzetti, S.; Guerci, L.; Farinacci, F.; Palazzini, G.; Parisi, A.; Tebala, G. D. - 04f Poster

congresso: European Society of Surgery President: Prof. Ferdinando Cafiero XXIV Annual Meeting JUNE, 28-29 2022 – Palazzo Ducale, Genoa (GENOVA)

libro: European Society of Surgery President: Prof. Ferdinando Cafiero XXIV Annual Meeting JUNE, 28-29 2022 – Palazzo Ducale, Genoa - ()

11573/1529296 - 2021 - Gastrectomy for stage IV gastric cancer. A comparison of different treatment strategies from the SEER database

Desiderio, Jacopo; Sagnotta, Andrea; Terrenato, Irene; Annibale, Bruno; Trastulli, Stefano; Tozzi, Federico; D'andrea, Vito; Bracarda, Sergio; Garofoli, Eleonora; Fong, Yuman; Woo, Yanghee; Parisi, Amilcare - 01a Articolo in rivista

rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000636269100010 (13) - scopus: 2-s2.0-85103743834 (13)

11573/1648194 - 2021 - Laparoscopic compared with open d2 gastrectomy on perioperative and long‐term, stage‐stratified oncological outcomes for gastric cancer. A propensity score‐matched analysis of the imigastric database.

Trastulli, S.; Desiderio, J.; Lin, J. -X.; Reim, D.; Zheng, C. -H.; Borghi, F.; Cianchi, F.; Norero, E.; Nguyen, N. T.; Qi, F.; Coratti, A.; Cesari, M.; Bazzocchi, F.; Alimoglu, O.; Brower, S. T.; Pernazza, G.; D'imporzano, S.; Azagra, J. -S.; Zhou, Y. -B.; Cao, S. -G.; Garofoli, E.; Mosillo, C.; Guerra, F.; Liu, T.; Arcuri, G.; Gonzalez, P.; Staderini, F.; Marano, A.; Terrenato, I.; D'andrea, V.; Bracarda, S.; Huang, C. -M.; Parisi, A. - 01a Articolo in rivista

rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000699110300001 (5) - scopus: 2-s2.0-85114357625 (3)

11573/1504220 - 2021 - Modified ypTNM Staging Classification for Gastric Cancer after Neoadjuvant Therapy: A Multi-Institutional Study

Zhong, Q.; Chen, Q. -Y.; Parisi, A.; Ma, Y. -B.; Lin, G. -T.; Desiderio, J.; Yan, S.; Xie, J. -W.; Wang, J. -B.; Hou, J. -F.; Lin, J. -X.; Lu, J.; Cao, L. -L.; Lin, M.; Tu, R. -H.; Huang, Z. -N.; Lin, J. -L.; Liu, Z. -Y.; Que, S. -J.; Li, P.; Zheng, C. -H.; Huang, C. -M. - 01a Articolo in rivista

rivista: THE ONCOLOGIST (Alphamed Press Incorporated:1 Prestige Place, Suite 290:Miamisburg, OH 45342:(937)291-2355, EMAIL: alphamedpress@alphamedpress.com, INTERNET: http://www.alphamedpress.com, Fax: (937)291-4229) pp. e99-e110 - issn: 1083-7159 - wos: WOS:000569925300001 (3) - scopus: 2-s2.0-85090995963 (5)

11573/1381314 - 2020 - Enhanced recovery after surgery for gastric cancer (ERAS-GC). Optimizing patient outcome

Desiderio, Jacopo; Trastulli, Stefano; D'andrea, Vito; Parisi, Amilcare - 01g Articolo di rassegna (Review)

rivista: TRANSLATIONAL GASTROENTEROLOGY AND HEPATOLOGY (Hong Kong : AME Publishing Company) pp. 1-7 - issn: 2415-1289 - wos: WOS:000504677300011 (16) - scopus: 2-s2.0-85085096298 (20)

11573/1659861 - 2020 - Safety of hospital discharge before return of bowel function after elective colorectal surgery

J Chapman, S; Blanco-Colino, R; P??Rez-Ajates, S; Anabitarte Bautista, O; Hodson, J; Blanco-Colino, R; J Chapman, S; C Glasbey, J; Pata, F; Pellino, G; A Soares, A Sgr??; Van Elst, T; Van Straten, S; Nepogodiev, D; Hodson, J; Borakati, A; F Bath, M; H Yasin, I; Mclean, K; Arthur, T; Kovacevic, M; Delibegovic, S; Karamanliev, M; Swamad, M; ??Ebr??K, R; Paramasivam, R; Martensen, A; M Larsen, H; R??Deker, L; E Frey, P; Kechagias, A; Venara, A; Duchalais, E; Ioannidis, A; Pata, F; Pellino, G; Pasquali, S; A Simioni, A Sgr??; Farina, V; Podda, M; Lorenzon, L; Itsurg, ; Schaeff, V; Otto, A; Jakubauskas, M; R Van Elst, T; Chu, M; B Fagan, P V; I Wells, C; Alagoa Jo??O, A; Soares, A; Juloski, J; Blanco-Colino, R; P??Rez-Ajates, S; Anabitarte Bautista, O; El Kasmy El Kasmi, Y; Espin-Basany, E; Clerc, D; Ciubotaru, C; Popescu, S; Yanishev, A; Lee, S; B Ozkan, B; Yag??Z Sen, A; K Aktas, M; E Baki, B; Y??Ksek, B; C Glasbey, J; Kamarajah, S; Mclean, K; Borakati, A; H Yasin, I; A Khaw, R; Mills, E; Goodson, R; Thakral, N; D Ablett, A; Adra, M; Kwek, I; M Khan, S; Quinn, P; R Manley, L; Badran, A; Ramjeeawon, A; Campbell, A; L Tan, H; S Rye, D; Rajaraman, N; G Norman, J; Vutipongsatorn, K; Solomou, G; Akhbari, M; Ali, A; D Brandao, B; Stainer, B; Thavayogan, R; Jones, D; O Onafowokan, O; Gharooni, A; Dabab, N; Carlton-Carew, S; Kungwengwe, G; Gabriel, M; Sewart, E; C Shortland, T; Lawday, S; Pockney, P; Dawson, A; Stewart, P; Ng, B; K Luong, J; Delibegovic, S; Ivanov, V; Borisova, A; Neykov, V; R ??Ebr??K, M Farka??Ov??; L Harbjerg, J; Brandsborg, S; Mark-Christensen, A; P Unbehaun, K; Dalsgaard, P; D Lycke, K; Kechagias, A; Lenaoures, P; Duchalais, E; Brigand, C; Dumange, E; Gout, M; Moehwald, C; Prem, M; Alhalabi, O; Sliwinski, S; Krupp, J; Gablenz, E; Schmitzer, L; Kopp, A; Steinle, J; Gsenger, J; J Pohl, L; Riccardi, M; M Christodoulou, I; Konstantinidis, M; Machairas, N; Zoikas, A; Balalis, D; K Manatakis, D; L Aguilera, M; A Simioni, A Sgr??; Marano, L; Fleres, F; Lovisetto, F; Sasia, D; Segalini, E; Pata, G; Lucchi, A; Sagnotta, A; Campagnaro, T; Petrelli, F; Gallo, G; Papandrea, M; Testa, V; Sinibaldi, G; Di Candido, F; Colombo, F; Perrone, G; Aresu, S; Biancafarina, A; Canonico, G; Pagnanelli, M; Curletti, G; Bini, R; De Manzoni Garberini, A; Impellizzeri, H; Cillara, N; Tutino, R; Picciariello, A; Coletta, D; Savino, G; Ferrara, F; Tamini, N; Talamo, G; Parini, D; Giamundo, P; Pagano, G; Ripetti, V; Pesce, A; Menduni, N; Pellino, G; Giudicissi, R; Podda, M; Goldin, E; Rega, D; Belli, A; Andriola, V; Gordini, L; Pata, F; Foppa, C; Piccolo, G; Birindelli, A; Ferrari, C; Ballarini, Z; Tirelli, F; Milone, M; De Rosa, M; S Pipitone Federico, N; Molteni, B; L Tilocca, P; Sancini, G; N Piozzi, G; Lauretta, A; Mulas, S; Schaeff, V; Otto, A; Jakubauskas, M; Simcikas, D; Portelli, L; M Van Wijnbergen, J W; L Dinger, T; H Ten Doesschate, S F; M Van Dalen, A S H; D Van Den Bos, D; Hansmann, M; Medina Feliz, J; Z Kuiper, S; Abdulrahman, Z; R Pruijssers, S; P Geneta, V; Chu, M; Wilton, S; Kandelaki, H; L Peng, S; Campbell, S; K Lim, Y; S Yassaie, S; Murray, M; B Fagan, P V; Haran, C; Tan, J; Castro, J; Laranjeira, A; Catarino, S; Neves-Marques, C; G Correia, J; N Vieira, B; C Quintela, A; L Serra, M; Maciel, J; Cunha, M; J Apar??Cio, D; Neves, J; Azevedo, J; Romano, M; Eir??, F; Romano, J; Monteiro, C; Claro, M; Almeida, ; Peyroteo, M; D Machado, N; Capote, H; Ferreira, M; Sousa, X; Devesa, H; Cavadas, D; Guerreiro, I; Costa, M; Rosete, M; Salman, M; English, C; Mohammed, N; Popescu, S; Yanishev, A; Litvin, A; V ??Uk, V; M??Sz??Rosov??, K; Van Straten, S; Jaich, R; De Lima, H; Brooks, S; Marx, M; Nshalati Salvation, M; Garc??A Cardo, J; Mora-Guzm??N, I; Sancho Muriel, J; De Andres Olabarria, U; Muriel, P; Jimenez Vi??As, C; Alconchel, F; Esteban Sinovas, O; El Kasmy El Kasmi, Y; Fair??N Oro, C; P??Rez-Ajates, S; L??Pez Otero, M; Figueroa Jim??Nez, S; Claramonte Bellmunt, O; Mart??Nez Caballero, J; Rubio-P??Rez, I; M Aguilar-Mart??Nez, M; J Segu - 01a Articolo in rivista

rivista: BRITISH JOURNAL OF SURGERY (Oxford: John Wiley & Sons Oxford: Oxford University Press Bristol: John Wright, 1913-) pp. 552-559 - issn: 0007-1323 - wos: WOS:000508958100001 (13) - scopus: 2-s2.0-85082094423 (18)

11573/1504230 - 2020 - Multicenter validation study of the American Joint Commission on Cancer (8th Edition) for gastric cancer: Proposal for a simplified and improved TNM staging system

Lin, J. -X.; Desiderio, J.; Lin, J. -P.; Wang, W.; Tu, R. -H.; Li, P.; Xie, J. -W.; Wang, J. -B.; Lu, J.; Chen, Q. -Y.; Cao, L. -L.; Lin, M.; Zheng, C. -H.; Zhou, Z. -W.; Parisi, A.; Huang, C. -M. - 01a Articolo in rivista

rivista: JOURNAL OF CANCER (Wyoming, N.S.W. : Ivyspring International Publisher, 2010-) pp. 3483-3491 - issn: 1837-9664 - wos: WOS:000522488200007 (4) - scopus: 2-s2.0-85082971404 (5)

11573/1504305 - 2019 - Fluorescence image-guided lymphadenectomy using indocyanine green and near infrared technology in robotic gastrectomy

Desiderio, J.; Trastulli, S.; Ricci, F.; Di Nardo, D.; D'andrea, V.; Parisi, A. - 04d Abstract in atti di convegno