11573/1390392 - 2020 -
Altered mitochondrial function in cells carrying a premutation or unmethylated full mutation of the FMR1 gene Nobile, V.; Palumbo, F.; Lanni, S.; Ghisio, V.; Vitali, A.; Castagnola, M.; Marzano, V.; Maulucci, G.; De Angelis, C.; De Spirito, M.; Pacini, L.; D'andrea, L.; Ragno, R.; Stazi, G.; Valente, S.; Mai, A.; Chiurazzi, P.; Genuardi, M.; Neri, G.; Tabolacci, E. - 01a Articolo in rivista
paper: HUMAN GENETICS (Germany: Springer Verlag Germany) pp. 227-245 - issn: 0340-6717 - wos: WOS:000515839900006 (19) - scopus: 2-s2.0-85077526115 (19)
11573/1394955 - 2020 -
Design of first-in-class dual EZH2/HDAC inhibitor: biochemical activity and biological evaluation in cancer cells Romanelli, Annalisa; Stazi, Giulia; Fioravanti, Rossella; Zwergel, Clemens; Di Bello, Elisabetta; Pomella, Silvia; Perrone, Clara; Battistelli, Cecilia; Strippoli, Raffaele; Tripodi, Marco; Del Bufalo, Donatella; Rota, Rossella; Trisciuoglio, Daniela; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 977-983 - issn: 1948-5875 - wos: WOS:000535281200056 (52) - scopus: 2-s2.0-85087681122 (56)
11573/1339079 - 2019 -
Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype Stazi, G.; Taglieri, L.; Nicolai, Alice; Romanelli, A.; Fioravanti, R.; Morrone, S.; Sabatino, M.; Ragno, R.; Taurone, S.; Nebbioso, M.; Carletti, R.; Artico, M.; Valente, S.; Scarpa, S.; Mai, A. - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. 1-17 - issn: 1868-7083 - wos: WOS:000501362500004 (54) - scopus: 2-s2.0-85076062797 (52)
11573/1208206 - 2019 -
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells Stazi, Giulia; Battistelli, Cecilia; Piano, Valentina; Mazzone, Roberta; Marrocco, Biagina; Marchese, Sara; Louie, Sharon M.; Zwergel, Clemens; Antonini, Lorenzo; Patsilinakos, Alexandros; Ragno, Rino; Viviano, Monica; Sbardella, Gianluca; Ciogli, Alessia; Fabrizi, Giancarlo; Cirilli, Roberto; Strippoli, Raffaele; Marchetti, Alessandra; Tripodi, Marco; Nomura, Daniel K.; Mattevi, Andrea; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 722-735 - issn: 0223-5234 - wos: WOS:000458597300053 (18) - scopus: 2-s2.0-85058530369 (17)
11573/1382317 - 2019 -
Lysine methyltransferases and their inhibitors Stazi, Giulia; Zwergel, Clemens; Valente, Sergio - 02a Capitolo o Articolo
book: Chemical Epigenetics - (978-3-030-42981-2; 978-3-030-42982-9)
11573/1275490 - 2019 -
Epigenetic Pharmacology in Regenerative Medicine (Epi-Drugs) Stazi, Giulia; Zwergel, Clemens; Valente, Sergio; Mai, Antonello - 02a Capitolo o Articolo
book: Epigenetics and Regeneration - (9780128148792)
11573/1265927 - 2019 -
Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells Zwergel, Clemens; Schnekenburger, Michael; Sarno, Federica; Battistelli, Cecilia; Manara, Maria Cristina; Stazi, Giulia; Mazzone, Roberta; Fioravanti, Rossella; Gros, Christina; Ausseil, Frédéric; Florean, Cristina; Nebbioso, Angela; Strippoli, Raffaele; Ushijima, Toshikazu; Scotlandi, Katia; Tripodi, Marco; Arimondo, Paola B.; Altucci, Lucia; Diederich, Marc; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. - - issn: 1868-7083 - wos: WOS:000467227900001 (28) - scopus: 2-s2.0-85065468885 (32)
11573/1174048 - 2018 -
Six years (2012-2018) of researches on catalytic EZH2 inhibitors: the boom of the 2-pyridone compounds Fioravanti, R; Stazi, G; Zwergel, C; Valente, S; Mai, A. - 01a Articolo in rivista
paper: THE CHEMICAL RECORD (New York N.Y.: Wiley, c2000-) pp. 1818-1832 - issn: 1527-8999 - wos: WOS:000453386600014 (87) - scopus: 2-s2.0-85055289007 (92)
11573/1147949 - 2018 -
A quinoline-based DNA methyltransferase inhibitor as a possible adjuvant in osteosarcoma therapy Manara, Maria Cristina; Valente, Sergio; Cristalli, Camilla; Nicoletti, Giordano; Landuzzi, Lorena; Zwergel, Clemens; Mazzone, Roberta; Stazi, Giulia; Arimondo, Paola B.; Pasello, Michela; Guerzoni, Clara; Picci, Piero; Nanni, Patrizia; Lollini, Pier-Luigi; Mai, Antonello; Scotlandi, Katia - 01a Articolo in rivista
paper: MOLECULAR CANCER THERAPEUTICS (Philadelphia, PA : American Association for Cancer Research, c2001-) pp. 1881-1892 - issn: 1535-7163 - wos: WOS:000444041300008 (34) - scopus: 2-s2.0-85053014459 (35)
11573/1147233 - 2018 -
Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells Mellini, Paolo; Marrocco, Biagina; Borovika, Diana; Polletta, Lucia; Carnevale, Ilaria; Saladini, Serena; Stazi, Giulia; Zwergel, Clemens; Trapencieris, Peteris; Ferretti, Elisabetta; Tafani, Marco; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: PHILOSOPHICAL TRANSACTIONS - ROYAL SOCIETY. BIOLOGICAL SCIENCES (Royal Society of London) pp. 20170150- - issn: 0962-8436 - wos: WOS:000430738400014 (21) - scopus: 2-s2.0-85045959069 (21)
11573/1202973 - 2018 -
Application of small epigenetic modulators in pediatric medulloblastoma Zwergel, Clemens; Romanelli, Annalisa; Stazi, Giulia; Besharat, Zein Mersini; Catanzaro, Giuseppina; Tafani, Marco; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: FRONTIERS IN PEDIATRICS (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-2360 - wos: WOS:000452081000001 (13) - scopus: 2-s2.0-85058706178 (15)
11573/1147235 - 2018 -
Trends of LSD1 inhibitors in viral infections Zwergel, Clemens; Stazi, Giulia; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 1133-1135 - issn: 1756-8919 - wos: WOS:000433568500001 (10) - scopus: 2-s2.0-85048066484 (10)
11573/1017610 - 2017 -
The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells Miele, Evelina; Valente, Sergio; Alfano, Vincenzo; Silvano, Marianna; Mellini, Paolo; Borovika, Diana; Marrocco, Biagina; Po, Agnese; Besharat, Zein Mersini; Catanzaro, Giuseppina; Battaglia, Giuseppe; Abballe, Luana; Zwergel, Clemens; Stazi, Giulia; Milite, Ciro; Castellano, Sabrina; Tafani, Marco; Trapencieris, Peteris; Mai, Antonello; Ferretti, Elisabetta - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 68557-68570- - issn: 1949-2553 - wos: WOS:000410790500145 (36) - scopus: 2-s2.0-85040235337 (38)
11573/1017602 - 2017 -
EZH2 inhibitors: a patent review (2014-2016) Stazi, Giulia; Zwergel, Clemens; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare
-London, United Kingdom: Ashley Publications Limited) pp. 797-813 - issn: 1354-3776 - wos: WOS:000405302700004 (38) - scopus: 2-s2.0-85020639378 (40)
11573/955887 - 2017 -
Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells Zwergel, Clemens; Czepukojc, Brigitte; Evain Bana, Emilie; Xu, Zhanjie; Stazi, Giulia; Mori, Mattia; Patsilinakos, Alexandros; Mai, Antonello; Botta, Bruno; Ragno, Rino; Bagrel, Denise; Kirsch, Gilbert; Meiser, Peter; Jacob, Claus; Montenarh, Mathias; Valente, Sergio - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 316-333 - issn: 0223-5234 - wos: WOS:000401677500027 (25) - scopus: 2-s2.0-85017548581 (27)
11573/870518 - 2016 -
LSD1 inhibitors: a patent review (2010-2015) Stazi, Giulia; Zwergel, Clemens; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare
-London, United Kingdom: Ashley Publications Limited) pp. 565-580 - issn: 1354-3776 - wos: WOS:000374900000003 (48) - scopus: 2-s2.0-84961644830 (49)
11573/856751 - 2016 -
Discovery of a novel inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) as orally active antitumor agent Vianello, Paola; Botrugno, Oronza A; Cappa, Anna; Dal Zuffo, Roberto; Dessanti, Paola; Mai, Antonello; Marrocco, Biagina; Mattevi, Andrea; Meroni, Giuseppe; Minucci, Saverio; Stazi, Giulia; Thaler, Florian; Trifiró, Paolo; Valente, Sergio; Villa, Manuela; Varasi, Mario; Mercurio, Ciro - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1501-1517 - issn: 0022-2623 - wos: WOS:000371103600018 (66) - scopus: 2-s2.0-84959421233 (69)
11573/779609 - 2015 -
Pyrrole- and indole-containing tranylcypromine derivatives as novel lysine-specific demethylase 1 inhibitors active on cancer cells. Veronica, Rodriguez; Valente, Sergio; Stefano, Rovida; Rotili, Dante; Stazi, Giulia; Lucidi, Alessia; Giuseppe, Ciossani; Andrea, Mattevi; Oronza A., Botrugno; Paola, Dessanti; Ciro, Mercurio; Paola, Vianello; Saverio, Minucci; Mario, Varasi; Mai, Antonello - 01a Articolo in rivista
paper: MEDCHEMCOMM (Cambridge : Royal Society of Chemistry, 2010-) pp. 665-670 - issn: 2040-2503 - wos: WOS:000352903400023 (22) - scopus: 2-s2.0-84928004801 (25)