GIORGIO GIARDINA

Associate professor

email: giorgio.giardina@uniroma1.it
phone: 0649910236
building: CU027
room: T4

Present Position:

Associate Professor - SSD BIO/10 - Dip. di Scienze Biochimiche Sapienza Università di Roma

Bio sketch:

Giorgio Giardina started his academic career in organic synthesis in 1999 and moved to Structural Biology in 2003, acquiring the PhD in 2006 in the Dep. of Biochemical Sciences at Sapienza University of Rome. He is now Associate Professor in Biochemistry and Structural Biology in the same department. During his career he has solved many protein structures using X-ray crystallography and has been mainly involved in the structure/function study of: i) Human PLP dependent enzyme such as Serine hydroxymethyltransferase (SHMT), Dopa decarboxylase (DDC) and Alanine:glyoxylate amino transferase (AGT) all involved in severe pathologies and/or cancer, ii) Proteins from Pseudomonas aeruginosa involved in the regulation of biofilm formation or/and the denitrification pathways. As many others in the field he is now combining X-ray crystallography and cryo-EM.

Teaching duties:

1. Biochemistry LM9: Structure and Function of Macromolecules

2. Biotecnologie Farmaceutiche LM-9: Biologia strutturale e Ingegneria Proteica

3. Biotecnologie mediche LM-9: biochimica e biologia strutturale - bioinformatica ed ingegneria proteica

4. Biochemistry LM9: Communication Skills

5. Tecnici di Laboratorio Biomedico (Forlanini): Basi Fisiche e Chimiche

6. PhD in Biochemistry and PhD in Life Sciences: Preparing Artwork for scientific papers

Publications:

For an updated list please visit: https://www.researchgate.net/profile/Giorgio_Giardina

Academic career

2022-2019 Research Associate L. 240/10 (Type b) - SSD BIO / 10 - Dip. di Scienze Biochimiche - Sapienza Università di Roma

2015-2018 Research Associate L. 240/10 (Type a - tempo Definito) - SSD BIO / 10 - Dip. di Scienze Biochimiche - Sapienza Università di Roma

2014 2015 Post-doctoral Fellow Pasteur Institute of Rome Fondazione Cenci-Bolognetti

Allosteric control in the synthesis and sensing of cyclic-di-GMP, a master regulator of bacterial growth and physiology

2012-2014 Post-Doctoral fellowship: SAPIENZA University of Rome. Biochemistry and structural biology of proteins involved in c-di-GMP pathway and quorum sensing

2011-2012 Post-Doctoral fellowship: SAPIENZA Università di Roma.Structural Characterization of proteins from Shistosoma mansoni and Plasmodium falciparum.

Whitin the following Project: Rational approach to the specific inhibition of Plasmodium falciparum and Shistosoma mansoni. Funding: FONDAZIONE ROMA

2009-2011 Post-Doctoral fellowship: SAPIENZA Università di Roma.Structural Caracterization of proteins involved in redox stress responce.

2007-2009 Post-Doctoral fellowship: SAPIENZA Università di Roma.Macromolecular Crystallography and structure-function study of proteins involved in Nitic Oxide/s sensing and regulation of denitrification and biofilm formation in Pseudomonas aeruginosa. Research Group of Prof. M. Brunori and Prof. F. Cutruzzolà

2003-2007. Ph.D. in Biochemistry: SAPIENZA Università di Roma. Thesis: The structure of the NO-sensing domain of the transcription factor DNR from P. aeruginosa

1999. Degree in Chemistry: SAPIENZA Università di Roma. Thesis: optimization of a new one-pot synthesis for organic and organo-metallic highly ethinylated homo-polymers and co-polymers.

Research products

11573/1725667 - 2024 - Sulfide:quinone oxidoreductase from the multidrug resistant pathogen Pseudomonas aeruginosa

Barile, Anna; Giordano, Francesca; Pistoia, Gianluca; Di Matteo, Adele; Giardina, Giorgio; Vicente, João B.; Forte, Elena; Giuffrè, Alessandro - 01h Abstract in rivista

paper: BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0005-2728 - wos: (0) - scopus: (0)

11573/1726477 - 2024 - Cytochrome bd-type oxidases and environmental stressors in microbial physiology

Borisov, Vitaliy B.; Giardina, Giorgio; Pistoia, Gianluca; Forte, Elena - 02a Capitolo o Articolo

book: Advances in Microbial Physiology, Vol 86 - ()

11573/1713419 - 2024 - Conformational and dynamic properties of the KH1 domain of FMRP and its fragile X syndrome linked G266E variant

Catalano, Flavia; Santorelli, Daniele; Astegno, Alessandra; Favretto, Filippo; D’Abramo, Marco; Del Giudice, Alessandra; De Sciscio, Maria Laura; Troilo, Francesca; Giardina, Giorgio; Di Matteo, Adele; Travaglini-Allocatelli, Carlo - 01a Articolo in rivista

paper: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (Tokyo ; Oxford ; New York ; London ; Amsterdam ; Shannon ; Paris : Elsevier) pp. 1-8 - issn: 1570-9639 - wos: WOS:001233726500001 (0) - scopus: 2-s2.0-85190942366 (0)

11573/1702420 - 2024 - Beyond the barrier: the immune-inspired pathways of tumor extravasation

Di Russo, S.; Liberati, F. R.; Riva, A.; Di Fonzo, F.; Macone, A.; Giardina, G.; Arese, M.; Rinaldo, S.; Cutruzzola, F.; Paone, A. - 01g Articolo di rassegna (Review)

paper: CELL COMMUNICATION AND SIGNALING (BioMed Central, London) pp. 104- - issn: 1478-811X - wos: WOS:001160608800001 (5) - scopus: 2-s2.0-85184788152 (6)

11573/1717778 - 2024 - Persulfide Dioxygenase from Pseudomonas aeruginosa unveils a novel crosstalk mechanism between the bioenergetically-relevant gaseous signaling molecules nitric oxide and hydrogen sulfide

Giordano, Francesca; Troilo, Francesca; Nastasi, Martina R.; Giardina, Giorgio; Allocatelli, Carlo Travaglini; Forte, Elena; Vicente, João B.; Di Matteo, Adele; Giuffrè, Alessandro - 01h Abstract in rivista

11573/1714195 - 2024 - Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1

Spizzichino, Sharon; Di Fonzo, Federica; Marabelli, Chiara; Tramonti, Angela; Chaves-Sanjuan, Antonio; Parroni, Alessia; Boumis, Giovanna; Liberati, Francesca Romana; Paone, Alessio; Montemiglio, Linda Celeste; Ardini, Matteo; Jakobi, Arjen J.; Bharadwaj, Alok; Swuec, Paolo; Tartaglia, Gian Gaetano; Paiardini, Alessandro; Contestabile, Roberto; Mai, Antonello; Rotili, Dante; Fiorentino, Francesco; Macone, Alberto; Giorgi, Alessandra; Tria, Giancarlo; Rinaldo, Serena; Bolognesi, Martino; Giardina, Giorgio; Cutruzzola, Francesca - 01a Articolo in rivista

paper: MOLECULAR CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 2682-2697 - issn: 1097-2765 - wos: WOS:001281962900001 (0) - scopus: 2-s2.0-85198588581 (0)

11573/1697907 - 2023 - Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study

Cellini, Barbara; Pampalone, Gioena; Camaioni, Emidio; Pariano, Marilena; Catalano, Flavia; Zelante, Teresa; Dindo, Mirco; Macchioni, Lara; Di Veroli, Alessandra; Galarini, Roberta; Paoletti, Fabiola; Davidescu, Magdalena; Stincardini, Claudia; Vascelli, Gianluca; Bellet, Marina Maria; Saba, Julie; Giovagnoli, Stefano; Giardina, Giorgio; Romani, Luigina; Costantini, Claudio - 01a Articolo in rivista

paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 22692- - issn: 2045-2322 - wos: WOS:001131702800073 (1) - scopus: 2-s2.0-85180264820 (1)

11573/1673921 - 2022 - Editorial: Tailored Modulation of Interactions Between Biomolecules: Fundamentals and Applications

Ardini, Matteo; Baiocco, Paola; Di Matteo, Adele; Giardina, Giorgio; Miele, Adriana Erica - 01m Editorial/Introduzione in rivista

paper: FRONTIERS IN MOLECULAR BIOSCIENCES (Lausanne : Frontiers Media S.A., 2014-) pp. 1-3 - issn: 2296-889X - wos: WOS:000834156100001 (1) - scopus: 2-s2.0-85135098533 (1)

11573/1575071 - 2022 - A conserved scaffold with heterogeneous metal ion binding site: the multifaceted example of HD-GYP proteins

Cutruzzolà, Francesca; Paiardini, Alessandro; Scribani Rossi, Chiara; Spizzichino, Sharon; Paone, Alessio; Giardina, Giorgio; Rinaldo, Serena - 01g Articolo di rassegna (Review)

paper: COORDINATION CHEMISTRY REVIEWS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 214228- - issn: 0010-8545 - wos: WOS:000706196900003 (3) - scopus: 2-s2.0-85115933139 (3)

11573/1628655 - 2022 - Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase

Dindo, Mirco; Pascarelli, Stefano; Chiasserini, Davide; Grottelli, Silvia; Costantini, Claudio; Uechi, Gen‐Ichiro; Giardina, Giorgio; Laurino, Paola; Cellini, Barbara - 01a Articolo in rivista

paper: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:000788245500032 (7) - scopus: 2-s2.0-85129109594 (8)

11573/1651824 - 2022 - Riboregulation as a new player in the control of cellular metabolism: clues from the cryo-EM structure of serine hydroxymethyltransferase-RNA complex

Giardina, Giorgio; Spizzichino, Sharon; Marabelli, Chiara; Di Fonzo, Federica; Tramonti, Angela; Parroni, Alessia; Contestabile, Roberto; Chaves, Antonio; Rinaldo, Serena; Bolognesi, Martino; Cutruzzola', Francesca - 04d Abstract in atti di convegno

conference: 17th SIBBM Seminar Frontiers in Molecular Biology - The RNA World 3.0 Abstracts (Roma)

book: Abstract Book - ()

11573/1661961 - 2022 - Folding mechanism and aggregation propensity of the KH0 domain of FMRP and its R138Q pathological variant

Santorelli, Daniele; Troilo, Francesca; Fata, Francesca; Angelucci, Francesco; Demitri, Nicola; Giardina, Giorgio; Federici, Luca; Catalano, Flavia; Di Matteo, Adele; Travaglini-Allocatelli, Carlo - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 12178- - issn: 1422-0067 - wos: WOS:000875286300001 (1) - scopus: 2-s2.0-85140969018 (1)

11573/1584599 - 2022 - Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex

Spizzichino, Sharon; Boi, Dalila; Boumis, Giovanna; Lucchi, Roberta; Liberati, Francesca Romana; Capelli, Davide; Montanari, Roberta; Pochetti, Giorgio; Piacentini, Roberta; Parisi, Giacomo; Paone, Alessio; Rinaldo, Serena; Contestabile, Roberto; Tramonti, Angela; Paiardini, Alessandro; Giardina, Giorgio; Cutruzzolà, Francesca - 01a Articolo in rivista

paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 1625-1649 - issn: 1742-464X - wos: WOS:000717476400001 (3) - scopus: 2-s2.0-85118844105 (4)

11573/1553790 - 2021 - The emerging role of amino acids of the brain microenvironment in the process of metastasis formation

Cutruzzola', Francesca; Bouzidi, Amani; Liberati, Francesca Romana; Spizzichino, Sharon; Boumis, Giovanna; Macone, Alberto; Rinaldo, Serena; Giardina, Giorgio; Paone, Alessio - 01g Articolo di rassegna (Review)

paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000666104500001 (4) - scopus: 2-s2.0-85107408621 (5)

11573/1492549 - 2021 - Studying ggdef domain in the act: Minimize conformational frustration to prevent artefacts

Mantoni, F.; Scribani Rossi, C.; Paiardini, A.; Di Matteo, A.; Cappellacci, L.; Petrelli, R.; Ricciutelli, M.; Paone, A.; Cutruzzola', F.; Giardina, G.; Rinaldo, S. - 01a Articolo in rivista

paper: LIFE (Basel: MDPI) pp. 1-13 - issn: 2075-1729 - wos: WOS:000610391100001 (4) - scopus: 2-s2.0-85100221529 (5)

11573/1551300 - 2021 - Modelling of SHMT1 riboregulation predicts dynamic changes of serine and glycine levels across cellular compartments

Monti, Michele; Guiducci, Giulia; Paone, Alessio; Rinaldo, Serena; Giardina, Giorgio; Liberati, Francesca Romana; Cutruzzolá, Francesca; Tartaglia, Gian Gaetano - 01a Articolo in rivista

paper: COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (Göteborg : Chalmers University of Technology, 2011-) pp. 3034-3041 - issn: 2001-0370 - wos: WOS:000684817100004 (9) - scopus: 2-s2.0-85106619221 (10)

11573/1551305 - 2021 - Importance of amino acids in brain parenchyma invasion by cancer cells

Paone, Alessio; Bouzidi, Amani; Rinaldo, Serena; Giardina, Giorgio; Cutruzzolà, Francesca - 01a Articolo in rivista

paper: ONCOSCIENCE (Impact Journals LLC -) pp. 47-49 - issn: 2331-4737 - wos: (0) - scopus: (0)

11573/1558512 - 2021 - L- Arginine in Pseudomonas aeruginosa controls c-di-GMP levels and biofilm formation

Scribani Rossi, Chiara; Mantoni, Federico; Giardina, Giorgio; Paiardini, Alessandro; Di Matteo, Adele; Cutruzzola', Francesca; Rinaldo, Serena - 04d Abstract in atti di convegno

conference: efb 2021 (online)

book: efb 2021 - ()

11573/1558505 - 2021 - Signal transduction and c-di-GMP second messenger: novel tools to investigare the mechanism of nutrient sensing.

Scribani Rossi, Chiara; Parisi, Giacomo; Giardina, Giorgio; Cutruzzola', Francesca; Paiardini, Alessandro; Rinaldo, Serena - 04d Abstract in atti di convegno

conference: WEBPRO - Proteins on the Web 2021. (online)

book: WEBPRO - Proteins on the Web 2021. - ()

11573/1553985 - 2021 - Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex

Spizzichino, Sharon; Boi, Dalila; Boumis, Giovanna; Tramonti, Angela; Paiardini, Alessandro; Contestabile, Roberto; Pochetti, Giorgio; Rinaldo, Serena; Paone, Alessio; Giardina, Giorgio; Cutruzzola', Francesca - 04d Abstract in atti di convegno

conference: 16th SIBBM Seminar Frontiers in Molecular Biology Frontiers in metabolic research (online)

book: 16th SIBBM Seminar Frontiers in Molecular Biology Frontiers in metabolic research Abstracts - ()

11573/1558518 - 2021 - Structural clues of Serine hidroxymethyltransferase (SHMT) riboregulation

Spizzichino, Sharon; Marabelli, Chiara; Chaves Sanjuan, Antonio; Swuec, Paolo; Montemiglio, Linda Celeste; Ardini, Matteo; Rinaldo, Serena; Paone, Alessio; Boumis, Giovanna; Giardina, Giorgio; Bolognesi, Martino; Cutruzzola', Francesca - 04d Abstract in atti di convegno

conference: 2nd Italian Crystallographic Association Biological MacroMolecules Group Meeting (online)

book: 2nd Italian Crystallographic Association Biological MacroMolecules Group Meeting - ()

11573/1568997 - 2021 - Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase

Spizzichino, Sharon; Pampalone, Gioena; Dindo, Mirco; Bruno, Agostino; Romani, Luigina; Cutruzzolà, Francesca; Zelante, Teresa; Pieroni, Marco; Cellini, Barbara; Giardina, Giorgio - 01a Articolo in rivista

paper: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. - - issn: 0887-3585 - wos: WOS:000696151200001 (1) - scopus: 2-s2.0-85114905178 (2)

11573/1573434 - 2021 - Metformin is a pyridoxal-5′-phosphate (PLP)-competitive inhibitor of SHMT2

Tramonti, A.; Cuyas, E.; Encinar, J. A.; Pietzke, M.; Paone, A.; Verdura, S.; Arbusa, A.; Martin-Castillo, B.; Giardina, G.; Joven, J.; Vazquez, A.; Contestabile, R.; Cutruzzola', F; Menendez, J. A. - 01a Articolo in rivista

paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000688842300001 (14) - scopus: 2-s2.0-85112661564 (16)

11573/1463758 - 2020 - Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity

Bouzidi, Amani; Magnifico, Maria Chiara; Paiardini, Alessandro; Macone, Alberto; Boumis, Giovanna; Giardina, Giorgio; Rinaldo, Serena; Liberati, Francesca Romana; Lauro, Clotilde; Limatola, Cristina; Lanzillotta, Chiara; Tramutola, Antonella; Perluigi, Marzia; Sgarbi, Gianluca; Solaini, Giancarlo; Baracca, Alessandra; Paone, Alessio; Cutruzzolà, Francesca - 01a Articolo in rivista

paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000595956300001 (10) - scopus: 2-s2.0-85096677891 (12)

11573/1648069 - 2020 - Structure and function of HD-GYP phosphodiesterases

Rinaldo, S.; Paiardini, A.; Paone, A.; Cutruzzola', F.; Giardina, G. - 02a Capitolo o Articolo

book: Microbial Cyclic Di-Nucleotide Signaling - (978-3-030-33307-2; 978-3-030-33308-9)

11573/1342273 - 2019 - Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: implications for primary hyperoxaluria type 1

Dindo, Mirco; Grottelli, Silvia; Annunziato, Giannamaria; Giardina, Giorgio; Pieroni, Marco; Pampalone, Gioena; Faccini, Andrea; Cutruzzolà, Francesca; Laurino, Paola; Costantino, Gabriele; Cellini, Barbara - 01a Articolo in rivista

paper: BIOCHEMICAL JOURNAL (London: Portland Press Limited London: Biochemical Society, 1984-) pp. 3751-3768 - issn: 0264-6021 - wos: WOS:000509881200005 (8) - scopus: 2-s2.0-85077107930 (8)

11573/1244108 - 2019 - The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism

Guiducci, Giulia; Paone, Alessio; Tramonti, Angela; Giardina, Giorgio; Rinaldo, Serena; Bouzidi, Amani; Magnifico, Maria C; Marani, Marina; Menendez, Javier A; Fatica, Alessandro; Macone, Alberto; Armaos, Alexandros; Tartaglia, Gian G; Contestabile, Roberto; Paiardini, Alessandro; Cutruzzolà, Francesca - 01a Articolo in rivista

paper: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. 1-16 - issn: 0305-1048 - wos: WOS:000473754300036 (28) - scopus: 2-s2.0-85067847112 (28)

11573/1330042 - 2019 - Linking infection and prostate cancer progression: Toll-like receptor3 stimulation rewires glucose metabolism in prostate cells

Magnifico, M. C.; Macone, A.; Marani, M.; Bouzidi, A.; Giardina, G.; Rinaldo, S.; Cutruzzola, F.; Paone, A. - 01a Articolo in rivista

paper: ANTICANCER RESEARCH (Kapandriti: International Institute of Anticancer Research, 1995 Earliest publisher: Καπανδρίτι: Ιωάννης Γ. Δεληνάσιος, 1981-1995 Kapandriti: Iōannīs G. Delīnasios, 1981-1995) pp. 5541-5549 - issn: 0250-7005 - wos: WOS:000488512600028 (6) - scopus: 2-s2.0-85072761348 (6)

11573/1273070 - 2019 - R180T variant of δ-ornithine aminotransferase associated with gyrate atrophy: biochemical, computational, X-ray and NMR studies provide insight into its catalytic features

Montioli, Riccardo; Paiardini, Alessandro; Giardina, Giorgio; Zanzoni, Serena; Cutruzzola, Francesca; Cellini, Barbara; Borri Voltattorni, Carla - 01a Articolo in rivista

paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. - - issn: 1742-464X - wos: WOS:000476663500011 (8) - scopus: 2-s2.0-85064506502 (9)

11573/1315822 - 2019 - N-acetylcysteine serves as substrate of 3-mercaptopyruvate sulfurtransferase and stimulates sulfide metabolism in colon cancer cells

Zuhra, Karim; Tomé, Catarina S; Masi, Letizia; Giardina, Giorgio; Paulini, Giulia; Malagrinò, Francesca; Forte, Elena; Vicente, João B; Giuffrè, Alessandro - 01a Articolo in rivista

paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 828- - issn: 2073-4409 - wos: WOS:000484537500061 (30) - scopus: 2-s2.0-85079506342 (32)

11573/1143149 - 2018 - The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells

Giardina, Giorgio; Paone, Alessio; Tramonti, Angela; Lucchi, Roberta; Marani, Marina; Magnifico, Maria Chiara; Bouzidi, Amani; Pontecorvi, Valentino; Guiducci, Giulia; Zamparelli, Carlotta; Rinaldo, Serena; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzolà, Francesca - 01a Articolo in rivista

paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 3238-3253 - issn: 1742-464X - wos: WOS:000443814200008 (27) - scopus: 2-s2.0-85052452668 (28)

11573/1139413 - 2018 - Insights into the GTP-dependent allosteric control of c-di-GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonas aeruginosa

Mantoni, Federico; Paiardini, Alessandro; Brunotti, Paolo; D'angelo, Cecilia; Cervoni, Laura; Paone, Alessio; Cappellacci, Loredana; Petrelli, Riccardo; Ricciutelli, Massimo; Leoni, Livia; Rampioni, Giordano; Arcovito, Alessandro; Rinaldo, Serena; Cutruzzolà, Francesca; Giardina, Giorgio - 01a Articolo in rivista

paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 3815-3834 - issn: 1742-464X - wos: WOS:000447880900011 (23) - scopus: 2-s2.0-85052825956 (26)

11573/1151881 - 2018 - A novel bacterial l-arginine sensor controlling c-di-GMP levels in Pseudomonas aeruginosa

Paiardini, A.; Mantoni, F.; Giardina, G.; Paone, A.; Janson, G.; Leoni, L.; Rampioni, G.; Cutruzzolà, F.; Rinaldo, S. - 01a Articolo in rivista

11573/1113671 - 2018 - Beyond nitrogen metabolism: nitric oxide, cyclic-di-GMP and bacterial biofilms

Rinaldo, Serena; Giardina, Giorgio; Mantoni, Federico; Paone, Alessio; Cutruzzolà, Francesca - 01g Articolo di rassegna (Review)

paper: FEMS MICROBIOLOGY LETTERS ([S.l.] : Blackwell S.l.] : Elsevier Science) pp. fny029- - issn: 1574-6968 - wos: WOS:000441109000002 (43) - scopus: 2-s2.0-85046858121 (44)

11573/1131469 - 2018 - Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes

Tramonti, Angela; Paiardini, Alessandro; Paone, Alessio; Bouzidi, Amani; Giardina, Giorgio; Guiducci, Giulia; Magnifico, Maria Chiara; Rinaldo, Serena; Mcdermott, Lee; Menendez, Javier A.; Contestabile, Roberto; Cutruzzolà, Francesca - 01a Articolo in rivista

paper: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (Attuale:ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, USA, NY, 10010-1710 Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 71-79 - issn: 0003-9861 - wos: WOS:000442192500007 (14) - scopus: 2-s2.0-85049429016 (13)

11573/954375 - 2017 - Glucose metabolism in the progression of prostate cancer

Cutruzzola', Francesca; Giardina, Giorgio; Marani, Marina; Macone, Alberto; Paiardini, Alessandro; Rinaldo, Serena; Paone, Alessio - 01a Articolo in rivista

paper: FRONTIERS IN PHYSIOLOGY (Lausanne: Frontiers Research Foundation, 2010-) pp. 97- - issn: 1664-042X - wos: WOS:000394487500001 (96) - scopus: 2-s2.0-85014162527 (105)

11573/1010852 - 2017 - Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis

Giardina, Giorgio; Paiardini, Alessandro; Montioli, Riccardo; Cellini, Barbara; Voltattorni, Carla Borri; Cutruzzola', Francesca - 01a Articolo in rivista

paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 11704- - issn: 2045-2322 - wos: WOS:000410859400036 (14) - scopus: 2-s2.0-85029469719 (14)

11573/952944 - 2017 - New insights emerging from recent investigations on Human Group II pyridoxal 5'-phosphate decarboxylases

Paiardini, Alessandro; Giardina, Giorgio; Rossignoli, Giada; Voltattorni, Carla Borri; Bertoldi, Mariarita - 01a Articolo in rivista

paper: CURRENT MEDICINAL CHEMISTRY (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 226-244 - issn: 0929-8673 - wos: WOS:000396017300001 (13) - scopus: 2-s2.0-85013635549 (12)

11573/1020398 - 2017 - Discovering selective diguanylate cyclase inhibitors: From PleD to discrimination of the active site of cyclic-di-GMP phosphodiesterases

Rinaldo, S.; Giardina, G.; Mantoni, F.; Paiardini, A.; Paone, Alessio; Cutruzzolã , Francesca - 02a Capitolo o Articolo

book: c-di-GMP signaling - (978-1-4939-7239-5; 978-1-4939-7240-1)

11573/1070158 - 2017 - CHAPTER 4: Nitrite Reductase - Cytochrome cd1

Rinaldo, Serena; Giardina, Giorgio; Cutruzzolà, Francesca - 02a Capitolo o Articolo

book: RSC Metallobiology - (978-1-78262-334-2)

11573/832010 - 2016 - In silico discovery and in vitro validation of catechol-containing sulfonohydrazide compounds as potent inhibitors of the diguanylate cyclase PleD

Fernicola, Silvia; Paiardini, Alessandro; Giardina, Giorgio; Rampioni, Giordano; Leoni, Livia; Cutruzzola', Francesca; Rinaldo, Serena - 01a Articolo in rivista

paper: JOURNAL OF BACTERIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 147-156 - issn: 0021-9193 - wos: WOS:000366587800006 (30) - scopus: 2-s2.0-84953898134 (39)

11573/845279 - 2016 - A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic hydroxymethyltransferase and induces cell death in lung cancer cells

Marani, Marina; Paone, Alessio; Fiascarelli, Alessio; Macone, Alberto; Gargano, Maurizio; Rinaldo, Serena; Giardina, Giorgio; Pontecorvi, Valentino; Koes, David; Mcdermott, Lee; Yang, Tianyi; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola, Francesca - 01a Articolo in rivista

paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 4570-4583 - issn: 1949-2553 - wos: WOS:000369952400069 (44) - scopus: 2-s2.0-84958012663 (43)

11573/832011 - 2015 - Synthesis of triazole-linked analogues of c-di-gmp and their interactions with diguanylate cyclase

Fernicola, Silvia; Torquati, Ilaria; Paiardini, Alessandro; Giardina, Giorgio; Rampioni, Giordano; Messina, Marco; Leoni, Livia; Del Bello, Fabio; Petrelli, Riccardo; Rinaldo, Serena; Cappellacci, Loredana; Cutruzzola', Francesca - 01a Articolo in rivista

paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8269-8284 - issn: 0022-2623 - wos: WOS:000363915600025 (30) - scopus: 2-s2.0-84945345287 (35)

11573/780499 - 2015 - How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state

Giardina, Giorgio; Brunotti, Paolo; Fiascarelli, Alessio; Cicalini, A; Costa, Mg; Buckle, Am; Di Salvo, Martino Luigi; Giorgi, Alessandra; Marani, Marina; Paone, Alessio; Rinaldo, Serena; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola', Francesca - 01a Articolo in rivista

paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. - - issn: 1742-464X - wos: WOS:000352226400005 (69) - scopus: 2-s2.0-84964265516 (79)

11573/780502 - 2015 - Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase

Paiardini, Alessandro; Fiascarelli, Alessio; Rinaldo, Serena; Daidone, Frederick; Giardina, Giorgio; Koes, Dr; Parroni, Alessia; Montini, G; Marani, Marina; Paone, Alessio; Mcdermott, La; Contestabile, Roberto; Cutruzzola', Francesca - 01a Articolo in rivista

paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 490-497 - issn: 1860-7179 - wos: WOS:000350456200006 (28) - scopus: 2-s2.0-84923349870 (29)

11573/781589 - 2015 - Structural basis of functional diversification of the HD-GYP domain revealed by the pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site

Rinaldo, Serena; Paiardini, Alessandro; Stelitano, Valentina; Brunotti, Paolo; Cervoni, Laura; Fernicola, Silvia; Protano, Carmela; Vitali, Matteo; Cutruzzola', Francesca; Giardina, Giorgio - 01a Articolo in rivista

paper: JOURNAL OF BACTERIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 1525-1535 - issn: 0021-9193 - wos: WOS:000351738600021 (28) - scopus: 2-s2.0-84930786571 (30)

11573/613990 - 2014 - Distal-proximal crosstalk in the heme binding pocket of the NO sensor DNR

Cutruzzola', Francesca; Alessandro, Arcovito; Giardina, Giorgio; Stefano Della, Longa; D'angelo, Paola; Rinaldo, Serena - 01a Articolo in rivista

paper: BIOMETALS (Rapid Science Publishers:2-6 Boundary Row, London SE1 8HN United Kingdom:011 44 207 9407500, EMAIL: rapidcom@vax.oxford.ac.uk, Fax: 011 44 207 8650027) pp. 763-773 - issn: 0966-0844 - wos: WOS:000339878700016 (14) - scopus: 2-s2.0-84905093005 (14)

11573/618583 - 2014 - SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation

Paone, Alessio; Marani, Marina; Fiascarelli, Alessio; Rinaldo, Serena; Giardina, Giorgio; Contestabile, Roberto; Paiardini, Alessandro; Cutruzzola', Francesca - 01a Articolo in rivista

paper: CELL DEATH & DISEASE (Nature Group) pp. e1525- - issn: 2041-4889 - wos: WOS:000345643900019 (90) - scopus: 2-s2.0-84923383679 (91)

11573/613995 - 2014 - Nitrosylation of c heme in cd(1)-nitrite reductase is enhanced during catalysis

Rinaldo, Serena; Giardina, Giorgio; Cutruzzola', Francesca - 01a Articolo in rivista

paper: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 449-454 - issn: 0006-291X - wos: WOS:000341553700018 (1) - scopus: 2-s2.0-84908365280 (1)

11573/534127 - 2013 - Investigating the allosteric regulation of YfiN from Pseudomonas aeruginosa: Clues from the structure of the catalytic domain

Giardina, Giorgio; Paiardini, Alessandro; Fernicola, Silvia; Stefano, Franceschini; Rinaldo, Serena; Stelitano, Valentina; Cutruzzola', Francesca - 01a Articolo in rivista

paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e81324- - issn: 1932-6203 - wos: WOS:000327541700059 (36) - scopus: 2-s2.0-84896718101 (40)

11573/509344 - 2013 - Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy

Stelitano, Valentina; A., Brandt; Fernicola, Silvia; S., Franceschini; Giardina, Giorgio; A., Pica; Rinaldo, Serena; F., Sica; Cutruzzola', Francesca - 01a Articolo in rivista

paper: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. e79-e79 - issn: 0305-1048 - wos: WOS:000318167900006 (33) - scopus: 2-s2.0-84876543297 (38)

11573/525774 - 2013 - C-di-GMP Hydrolysis by Pseudomonas aeruginosa HD-GYP Phosphodiesterases: Analysis of the Reaction Mechanism and Novel Roles for pGpG

Stelitano, Valentina; Giardina, Giorgio; Paiardini, Alessandro; Castiglione, Nicoletta; Cutruzzola', Francesca; Rinaldo, Serena - 01a Articolo in rivista

paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e74920- - issn: 1932-6203 - wos: WOS:000324494000139 (46) - scopus: 2-s2.0-84884194723 (50)

11573/485008 - 2012 - Crystal structure of Plasmodium falciparum thioredoxin reductase, a validated drug target

Boumis, Giovanna; Giardina, Giorgio; Angelucci, Francesco; Bellelli, Andrea; Brunori, Maurizio; Dimastrogiovanni, Daniela; Saccoccia, Fulvio; Miele, Adriana Erica - 01a Articolo in rivista

paper: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 806-811 - issn: 0006-291X - wos: WOS:000309017700019 (24) - scopus: 2-s2.0-84865977017 (24)

11573/435909 - 2012 - Nitrite and Nitrite Reductases: From Molecular Mechanisms to Significance in Human Health and Disease

Castiglione, Nicoletta; Rinaldo, Serena; Giardina, Giorgio; Stelitano, Valentina; Cutruzzola', Francesca - 01a Articolo in rivista

paper: ANTIOXIDANTS & REDOX SIGNALING (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 684-716 - issn: 1523-0864 - wos: WOS:000305470500010 (52) - scopus: 2-s2.0-84862566342 (55)

11573/442251 - 2012 - Identification by Virtual Screening and In Vitro Testing of Human DOPA Decarboxylase Inhibitors

Daidone, Frederick; Riccardo, Montioli; Paiardini, Alessandro; Barbara, Cellini; Antonio, Macchiarulo; Giardina, Giorgio; Bossa, Francesco; Carla Borri, Voltattorni - 01a Articolo in rivista

paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e31610-e31610 - issn: 1932-6203 - wos: WOS:000302916100026 (54) - scopus: 2-s2.0-84857609756 (60)

11573/441049 - 2012 - Unusual Heme Binding Properties of the Dissimilative Nitrate Respiration Regulator, a Bacterial Nitric Oxide Sensor

Rinaldo, Serena; Castiglione, Nicoletta; Giardina, Giorgio; Caruso, Manuela; Alessandro, Arcovito; S., Della Longa; D'angelo, Paola; Cutruzzola', Francesca - 01a Articolo in rivista

paper: ANTIOXIDANTS & REDOX SIGNALING (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 1178-1189 - issn: 1523-0864 - wos: WOS:000308405800002 (21) - scopus: 2-s2.0-84865627725 (23)

11573/375989 - 2011 - Metabolism of cyclic-di-GMP in bacterial biofilms: From a general overview to biotechnological applications

Castiglione, Nicoletta; Stelitano, Valentina; Rinaldo, Serena; Giardina, Giorgio; Cutruzzola', Francesca - 01a Articolo in rivista

paper: INDIAN JOURNAL OF BIOTECHNOLOGY (New Delhi : National Institute of Science Communication and Information Resources, CSIR) pp. 423-431 - issn: 0972-5849 - wos: WOS:000297905800007 (5) - scopus: 2-s2.0-83455170648 (5)

11573/387166 - 2011 - Structure and function of the DNR transcription factor, a master regulator of nitric oxide homeostasis in Pseudomonas aeruginosa

Cutruzzola', Francesca; Rinaldo, Serena; Giardina, Giorgio; Castiglione, Nicoletta; Caruso, M.; Arcovito, A.; Della Longa, S.; D'angelo, Paola - 04c Atto di convegno in rivista

paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 166-166 - issn: 1742-4658 - wos: WOS:000292333101293 (0) - scopus: (0)

conference: 36th FEBS Congress, Biochemistry for Tomorrow's Medicine (Lingotto Conference Center, Torino, Italy)

11573/389297 - 2011 - IDENTIFICATION BY VIRTUAL SCREENING AND IN VITRO TESTING OF NOVEL HUMAN DOPA DECARBOXYLASE INHIBITORS

F., Daidone; R., Montioli; Paiardini, Alessandro; B., Cellini; A., Macchiarulo; Giardina, Giorgio; Bossa, Francesco; C., Borri Voltattorni - 04d Abstract in atti di convegno

conference: FEBS Congress 2011 (Torino)

11573/359031 - 2011 - The Pseudomonas aeruginosa DNR transcription factor: light and shade of nitric oxide sensing mechanism.

Giardina, Giorgio; Castiglione, Nicoletta; Caruso, Manuela; Cutruzzola', Francesca; Rinaldo, Serena - 01a Articolo in rivista

paper: BIOCHEMICAL SOCIETY TRANSACTIONS (Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331) pp. 294-298 - issn: 0300-5127 - wos: WOS:000287438000053 (25) - scopus: 2-s2.0-79551487830 (26)

11573/410615 - 2011 - Crystal structure of the apo form of human aromatic L-amino acid decarboxylase: an open conformation unveils novel insights into the mechanism of PLP addition to the apoenzymes of group II decarboxylases

Giardina, Giorgio; Montioli, R.; Gianni, Stefano; Cellini, B.; Paiardini, Alessandro; Voltattorni, Cb; Cutruzzola', Francesca - 04d Abstract in atti di convegno

paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 263-263 - issn: 1742-464X - wos: WOS:000292333102058 (0) - scopus: (0)

conference: 36th FEBS Congress of the Biochemistry for Tomorrows Medicine (Torino, ITALY)

11573/426205 - 2011 - Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases

Giardina, Giorgio; R., Montioli; Gianni, Stefano; B., Cellini; Paiardini, Alessandro; C., Borri Voltattorni; Cutruzzola', Francesca - 01a Articolo in rivista

paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 20514-20519 - issn: 0027-8424 - wos: WOS:000298289400055 (88) - scopus: 2-s2.0-84855517335 (86)

11573/359034 - 2011 - The catalytic mechanism of Pseudomonas aeruginosa cd1 nitrite reductase

Rinaldo, Serena; Giardina, Giorgio; Castiglione, Nicoletta; Stelitano, Valentina; Cutruzzola', Francesca - 01a Articolo in rivista

paper: BIOCHEMICAL SOCIETY TRANSACTIONS (Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331) pp. 195-200 - issn: 0300-5127 - wos: WOS:000287438000034 (20) - scopus: 2-s2.0-79551504905 (21)

11573/411203 - 2011 - Characterization of proteins from Pseudomonas aeruginosa involved in c-di-GMP turnover

Stelitano, Valentina; Caruso, Manuela; Castiglione, Nicoletta; Giardina, Giorgio; Rinaldo, Serena; Cutruzzola', Francesca - 04d Abstract in atti di convegno

paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 172-173 - issn: 1742-464X - wos: WOS:000292333101314 (0) - scopus: (0)

conference: 36th FEBS Congress of the Biochemistry for Tomorrows Medicine (Torino, ITALY)

11573/411221 - 2010 - Inhibition Of Bacterial Biofilms: New Molecular Strategies Targeting Cyclic-Di-GMP Metabolism.

Stelitano, Valentina; Rinaldo, Serena; Giardina, Giorgio; Castiglione, Nicoletta; Cutruzzola', Francesca - 04a Atto di comunicazione a congresso

conference: International Conference on Genomic Sciences 2010(ICGS 2010) (Madurai (India))

11573/411378 - 2009 - Nitrite reduction, a function emerging from a pre-aerobic past

Brunori, Maurizio; Castiglione, Nicoletta; Giardina, Giorgio; I., Pecht; Rinaldo, Serena; Cutruzzola', Francesca - 04a Atto di comunicazione a congresso

conference: 54mo Congresso Societa' Biochimica e Biologia Molecolare (Catania (I))

11573/411382 - 2009 - THE TRANSCRIPTION FACTOR DNR FROM PSEUDOMONAS AERUGINOSA SPECIFICALLY REQUIRES NITRIC OXIDE AND HEME FOR THE ACTIVATION OF A TARGET PROMOTER IN ESCHERICHIA COLI

Castiglione, Nicoletta; Rinaldo, Serena; Giardina, Giorgio; Caruso, Manuela; Brunori, Maurizio; Cutruzzola', Francesca - 04a Atto di comunicazione a congresso

conference: 54mo Convegno Societa' Biochimica e Biologia Molecolare (Catania (I))

11573/359009 - 2009 - The transcription factor DNR from Pseudomonas aeruginosa specifically requires nitric oxide and haem for the activation of a target promoter in Escherichia coli

Castiglione, Nicoletta; Rinaldo, Serena; Giardina, Giorgio; Cutruzzola', Francesca - 01a Articolo in rivista

paper: MICROBIOLOGY (Society for General Microbiology:Marlboro House, Basingstoke Road, Spencers Wood, Reading RG7 1AE United Kingdom:011 44 118 9881814, EMAIL: d.smith@sgm.ac.ukadmin@socgenmicrobiol.org.uk, INTERNET: http://www.sgm.ac.uk, Fax: 011 44 118 9885656) pp. 2838-2844 - issn: 1350-0872 - wos: WOS:000270264300004 (47) - scopus: 2-s2.0-69949151824 (45)

11573/358279 - 2009 - Nitrite reduction: a ubiquitous function from a pre-aerobic past

Cutruzzola', Francesca; Rinaldo, Serena; Castiglione, Nicoletta; Giardina, Giorgio; Israel, Pecht; Brunori, Maurizio - 01a Articolo in rivista

paper: BIOESSAYS (-HOBOKEN, USA, NJ: JOHN WILEY & SONS INC -Cambridge : Cambridge University Press, 1984-) pp. 885-891 - issn: 0265-9247 - wos: WOS:000268762500009 (15) - scopus: 2-s2.0-70349972020 (15)

11573/411372 - 2009 - DNR FROM PSEUDOMONAS AERUGINOSA: STRUCTURAL AND SPECTROSCOPIC PROPERTIES OF A BACTERIAL NO-SENSOR

Giardina, Giorgio; Rinaldo, Serena; Castiglione, Nicoletta; Caruso, Manuela; Arcovito, A.; Della Longa, S.; D’Angelo, P.; Brunori, Maurizio; Cutruzzola', Francesca - 04a Atto di comunicazione a congresso

conference: 54 Convegno Società Italiana di Biochimica e Biologia Molecolare (Catania)

11573/357837 - 2009 - A dramatic conformational rearrangement is necessary for the activation of DNR from Pseudomonas aeruginosa. Crystal structure of wild type DNR

Giardina, Giorgio; Rinaldo, Serena; Castiglione, Nicoletta; Caruso, Manuela; Cutruzzola', Francesca - 01a Articolo in rivista

paper: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 174-180 - issn: 0887-3585 - wos: WOS:000269300000015 (30) - scopus: 2-s2.0-70349334424 (28)

11573/411240 - 2009 - BIOFILM FORMATION IN THE HUMAN PATHOGEN PSEUDOMONAS AERUGINOSA: A STRUCTURAL BIOLOGY STUDY OF PROTEINS INVOLVED IN c-diGMP HOMEOSTASIS

Giardina, Giorgio; Stelitano, Valentina; Rinaldo, Serena; Castiglione, Nicoletta; Caruso, Manuela; Brunori, Maurizio; Cutruzzola', Francesca - 04a Atto di comunicazione a congresso

conference: EUROBIOFILMS 2009 (ROMA (I))

11573/44486 - 2009 - XAS study of the active site of a bacterial heme-sensor

S., Della Longa; A., Arcovito; Brunori, Maurizio; Castiglione, Nicoletta; Cutruzzola', Francesca; D'angelo, Paola; Giardina, Giorgio; Rinaldo, Serena - 01a Articolo in rivista

paper: JOURNAL OF PHYSICS. CONFERENCE SERIES (Bristol : Institute of Physics Publishing) pp. 012202-012202 - issn: 1742-6588 - wos: WOS:000275152100203 (1) - scopus: 2-s2.0-73449111238 (1)

11573/359022 - 2008 - NO-sensing in Pseudomonas aeruginosa: Structure of the transcriptional regulator DNR

Giardina, Giorgio; Rinaldo, Serena; Johnson K., A; Di Matteo, Adele; Brunori, Maurizio; Cutruzzola', Francesca - 01a Articolo in rivista

paper: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, -London; New York: Academic Press.) pp. 1002-1015 - issn: 0022-2836 - wos: WOS:000256171900004 (70) - scopus: 2-s2.0-42649125235 (71)

11573/358998 - 2008 - New insights into the activity of Pseudomonas aeruginosa cd(1) nitrite reductase

Rinaldo, Serena; Arcovito, A; Giardina, Giorgio; Castiglione, Nicoletta; Brunori, Maurizio; Cutruzzola', Francesca - 01a Articolo in rivista

paper: BIOCHEMICAL SOCIETY TRANSACTIONS (Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331) pp. 1155-1159 - issn: 0300-5127 - wos: WOS:000261749200011 (18) - scopus: 2-s2.0-59149088482 (17)

conference: Biochemical Society Focused Meeting Transition metals in biochemistry (Norwich; United Kingdom)

book: Biochemical Society Focused Meeting Transition metals in biochemistry - ()

11573/361552 - 2006 - N-oxide sensing and denitrification: the DNR transcription factors

Rinaldo, Serena; Giardina, Giorgio; Brunori, Maurizio; Cutruzzola', Francesca - 01a Articolo in rivista

paper: BIOCHEMICAL SOCIETY TRANSACTIONS (Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331) pp. 185-187 - issn: 0300-5127 - wos: WOS:000235265500048 (13) - scopus: 2-s2.0-32544450194 (14)

conference: 11th Nitrogen Cycle Meeting (Granada, SPAIN)

11573/338258 - 2005 - Use of the Pd-promoted Extended One Pot (EOP) Synthetic Protocol for the Modular Construction of Poly-(arylene ethynylene) copolymers [-Ar-C≡C-Ar’-C≡C-]n, Opto- and Electro-Responsive Materials for Advanced Technology

A., Micozzi; M., Ottaviani; Giardina, Giorgio; A., Ricci; R., Pizzoferrato; T., Ziller; D., Compagnone; C., Lo Sterzo - 01a Articolo in rivista

paper: ADVANCED SYNTHESIS & CATALYSIS (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 143-160 - issn: 1615-4150 - wos: WOS:000226776100015 (17) - scopus: 2-s2.0-14644443526 (18)

11573/359020 - 2005 - N-oxide sensing in Pseudomonas aeruginosa: expression and preliminary characterization of DNR, an FNR-CRP type transcriptional regulator.

Rinaldo, Serena; Giardina, Giorgio; Brunori, Maurizio; Cutruzzola', Francesca - 01a Articolo in rivista

paper: BIOCHEMICAL SOCIETY TRANSACTIONS (Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331) pp. 184-186 - issn: 0300-5127 - wos: WOS:000227269800054 (7) - scopus: 2-s2.0-14644401763 (7)

11573/360764 - 2001 - Use of the extended one-pot (EOP) procedure for the preparation of ethynylated thiophene derivatives and related palladium-ethynylthiophene organometallic oligomers

Altamura, P; Giardina, Giorgio; Lo Sterzo, C; Russo, Maria Vittoria - 01a Articolo in rivista

paper: ORGANOMETALLICS (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 4360-4368 - issn: 0276-7333 - wos: WOS:000171596600009 (28) - scopus: 2-s2.0-0035889202 (34)

11573/338260 - 2000 - An Efficient One-Pot Access to Poly(arylene ethynylene) Homopolimers: Use of the Bu3Sn-Moiety as Recyclable carrier to Introduce the Ethynyl Unit into the Chain

Giardina, Giorgio; Rosi, P; Ricci, A; Lo Sterzo, C. - 01a Articolo in rivista

paper: JOURNAL OF POLYMER SCIENCE. PART A, POLYMER CHEMISTRY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 2603-2621 - issn: 0887-624X - wos: (0) - scopus: 2-s2.0-0033685839 (21)