GIANLUCA CANETTIERI

Full professor

email: gianluca.canettieri@uniroma1.it
phone: 06/49255130
building: Regina Elena Edificio B (RM110)
room: 219

PRESENT POSITION

Full Professor, General Pathology, MED/04
Department of Molecular Medicine
Sapienza University of Rome
Viale Regina Elena 291 - 00161 Roma



ADDITIONAL POSITIONS

- Head of Epigenetics, Metabolism and Cancer Unit, Department of Molecular Medicine, Sapienza University of Rome
- PI - Nutrition and Cancer Research (NACRe) European Consortium
- Secretary of the Board of Full Professors SSD Med/04
- Secretary-Treasurer of the Italian Society of Pathology and Translational Medicine (SIPMeT)



EDUCATION AND CAREER

2019- today: Full Professor, General Pathology (SSD MED/04), Dept. Molecular Medicine, University La Sapienza.
2008 – 2019: Associate Professor, General Pathology (SSD MED/04), Dept. Molecular Medicine, University La Sapienza
2005-2008: Assistant Professor of Pathology c/o Department of Experimental Medicine and Pathology. Programma Rientro dei Cervelli - MIUR - University of Rome “La Sapienza”
2000-2005 Research Associate, Salk Institute for Biological Studies, Peptide Biology laboratories, La Jolla, CA.
1996-2000: PhD in Endocrinology and Metabolic Sciences at the University “La Sapienza”, Rome
1996: Visiting fellow at the Geriatric Division of the Johns Hopkins University, Baltimore MD USA.
1996: Board certification for medical practice
1995: Medical Doctor degree, Graduation cum laude

MOST RELEVANT RESEARCH LINES

1. Energy and redox alterations in cancer (colorectal and medulloblastoma) and their targeting with metabolic drugs and diet.
2. Polyamine metabolism and hypusination pathway in cancer and muscle disease.
3. Molecular mechanisms regulating MYC in colorectal cancer and their targeting
4. Discovery of novel compounds targeting WNT pathway, epigenetic and metabolic alterations in colorectal cancer and medulloblastoma

COLLABORATIONS:

Salk Institute for Biological Studies, La Jolla, CA; The Burnham Institute, La Jolla, CA; Scripps Research institute, San Diego, CA; University of Toronto, Canada; University of Florida, FL; Harvard Medical School, Boston, MA; Whitehead Institute for Biomedical Research, Cambridge, MA; University of Illinois College of Medicine, Chicago, IL; Osaka University, Osaka, Japan; Johns Hopkins University, Baltimore, MD; University of Maryland, Baltimore, MD; University of Warzav, Poland; École Polytechnique Fédérale de Lausanne, Switzerland; University of Leeds, UK; McMaster University, Canada; Michigan State University, MI, USA
Università di Palermo; Università di Bari; Università di Pisa, Università di Messina; Università di Siena, Università di Roma Tor Vergata; Università Cattolica del Sacro Cuore, Roma; Consiglio Nazionale delle Ricerche, Roma e Napoli, Italian Institute of Tecnology, Rome, Consorzio Mario Negri Sud, Santa Maria Imbaro, Chieti, Cancer Genetics Laboratory, IRCCS S. de Bellis, Castellana Grotte; IRBM-Merck Research Laboratories Rome; Ente Per Le Nuove Technologie, l'Energia e l'Ambiente (ENEA), Centro Ricerche Casaccia, Casaccia, Roma; Neuromed Institute Pozzilli, Isernia; Istituto Nazionale della Nutrizione, Roma



FIVE SELECTED PUBLICATIONS

Coni S, Falconio FA, Marzullo M, Munafò M, Zuliani B, Mosti F, Fatica A, Ianniello Z, Bordone R, Macone A, Agostinelli E, Perna A, Matkovic T, Sigrist S, Silvestri G, Canettieri G*, Ciapponi L*. Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function. Elife. 2021 Sep 14;10:e69269. doi: 10.7554/eLife.69269. PMID: 34517941 Free PMC article.

Di Magno L, Manni S, Di Pastena F, Coni S, Macone A, Cairoli S, Sambucci M, Infante P, Moretti M, Petroni M, Nicoletti C, Capalbo C, De Smaele E, Di Marcotullio L, Giannini G, Battistini L, Goffredo BM, Iorio E, Agostinelli E, Maroder M, Canettieri G. Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module. Cell Rep. 2020 Feb 11;30(6):1735-1752.e7. doi: 10.1016/j.celrep.2020.01.024.

Coni S, Serrao SM, Yurtsever ZN, Di Magno L, Bordone R, Bertani C, Licursi V, Ianniello Z, Infante P, Moretti M, Petroni M, Guerrieri F, Fatica A, Macone A, De Smaele E, Di Marcotullio L, Giannini G, Maroder M, Agostinelli E, Canettieri G Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation. Cell Death Dis. 2020 Dec 10;11(12):1045. doi: 10.1038/s41419-020-03174

Coni S, Mancuso AB, Di Magno L, Sdruscia G, Manni S, Serrao S, Rotili D, Spiombi E, Bufalieri F, Petroni ML, Kusio-Kobialka M, De Smaele E, Ferretti E, Capalbo C, Mai A, Niewiadomski P, Screpanti I, Di Marcotullio L and Canettieri G Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma Sci Rep. 2017 Mar 9;7:44079. doi: 10.1038/srep44079.

D'Amico D, Antonucci L, Di Magno L, Coni S, Sdruscia G, Macone A, Miele E, Infante P, Di Marcotullio L, De Smaele E, Ferretti E, Ciapponi L, Giangaspero F, Yates JR 3rd, Agostinelli E, Cardinali B, Screpanti I, Gulino A, Canettieri G. Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth. Dev Cell. 2015 Oct 12;35(1):21-35. doi: 10.1016/j.devcel.2015.09.008.

Research products

11573/1692856 - 2024 - SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma
Lospinoso Severini, Ludovica; Loricchio, Elena; Navacci, Shirin; Basili, Irene; Alfonsi, Romina; Bernardi, Flavia; Moretti, Marta; Conenna, Marilisa; Cucinotta, Antonino; Coni, Sonia; Petroni, Marialaura; De Smaele, Enrico; Giannini, Giuseppe; Maroder, Marella; Canettieri, Gianluca; Mastronuzzi, Angela; Guardavaccaro, Daniele; Ayrault, Olivier; Infante, Paola; Bufalieri, Francesca; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. - - issn: 1350-9047 - wos: WOS:001119029000002 (2) - scopus: 2-s2.0-85178929821 (2)

11573/1666339 - 2023 - Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability
Caballero-Ruiz, Begoña; Gkotsi, Danai S; Ollerton, Hattie; Morales-Alcala, Cintli C; Bordone, Rosa; Jenkins, Georgia M L; Di Magno, Laura; Canettieri, Gianluca; Riobo-Del Galdo, Natalia A - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. 369- - issn: 2072-6694 - wos: WOS:000916870000001 (0) - scopus: 2-s2.0-85146751743 (0)

11573/1674490 - 2023 - Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation
Coni, Sonia; Bordone, Rosa; Ivy, Devon Michael; Yurtsever, Zuleyha Nihan; Di Magno, Laura; D'amico, Rodrigo; Cesaro, Bianca; Fatica, Alessandro; Belardinilli, Francesca; Bufalieri, Francesca; Maroder, Marella; De Smaele, Enrico; Di Marcotullio, Lucia; Giannini, Giuseppe; Agostinelli, Enzo; Canettieri, Gianluca - 01a Articolo in rivista
paper: CANCER LETTERS (Elsevier Science Ireland Limited:PO Box 85, Limerick Ireland:011 353 61 709600, 011 353 61 61944, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 353 61 709114) pp. - - issn: 0304-3835 - wos: WOS:000955037000001 (8) - scopus: 2-s2.0-85150380153 (9)

11573/1687401 - 2023 - KCTD1 is a new modulator of the KCASH family of Hedgehog suppressors
Di Fiore, A; Bellardinelli, S; Pirone, L; Russo, R; Angrisani, A; Terriaca, G; Bowen, M; Bordin, F; Besharat, Z M; Canettieri, G; Fabretti, F; Di Gaetano, S; Di Marcotullio, L; Pedone, E; Moretti, M; De Smaele, E - 01a Articolo in rivista
paper: NEOPLASIA (Basingstoke: Nature Publishing Group.) pp. 1-12 - issn: 1476-5586 - wos: WOS:001144756100001 (2) - scopus: 2-s2.0-85168719034 (2)

11573/1691148 - 2023 - Modeling myotonic dystrophy type 2 using Drosophila melanogaster
Marzullo, Marta; Coni, Sonia; De Simone, Assia; Canettieri, Gianluca; Ciapponi, Laura - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 14182-14194 - issn: 1422-0067 - wos: WOS:001073894300001 (0) - scopus: 2-s2.0-85173034988 (0)

11573/1696179 - 2023 - 4-(3-Phenyl-4-(3,4,5-trimethoxybenzoyl)-1H-pyrrol-1-yl)benzenesulfonamide, a Novel Carbonic Anhydrase and Wnt/β-Catenin Signaling Pathway Dual-Targeting Inhibitor with Potent Activity against Multidrug Resistant Cancer Cells
Masci, Domiziana; Puxeddu, Michela; Di Magno, Laura; D'ambrosio, Michele; Parisi, Anastasia; Nalli, Marianna; Bai, Ruoli; Coluccia, Antonio; Sciò, Pietro; Orlando, Viviana; D'angelo, Sara; Biagioni, Stefano; Urbani, Andrea; Hamel, Ernest; Nocentini, Alessio; Filiberti, Serena; Turati, Marta; Ronca, Roberto; Kopecka, Joanna; Riganti, Chiara; Fionda, Cinzia; Bordone, Rosa; Della Rocca, Giorgia; Canettieri, Gianluca; Supuran, Claudiu T; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 14824-14842 - issn: 1520-4804 - wos: WOS:001096765200001 (1) - scopus: 2-s2.0-85176509722 (1)

11573/1684557 - 2023 - Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent
Nalli, Marianna; Di Magno, Laura; Wen, Yichao; Liu, Xin; D’Ambrosio, Michele; Puxeddu, Michela; Parisi, Anastasia; Sebastiani, Jessica; Sorato, Andrea; Coluccia, Antonio; Ripa, Silvia; Di Pastena, Fiorella; Capelli, Davide; Montanari, Roberta; Masci, Domiziana; Urbani, Andrea; Naro, Chiara; Sette, Claudio; Orlando, Viviana; D’Angelo, Sara; Biagioni, Stefano; Bigogno, Chiara; Dondio, Giulio; Pastore, Arianna; Stornaiuolo, Mariano; Canettieri, Gianluca; Liu, Te; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (Washington DC: American Chemical Society) pp. 1087-1103 - issn: 2575-9108 - wos: WOS:001022871100001 (0) - scopus: 2-s2.0-85164931909 (0)

11573/1685768 - 2023 - Thiol functionalised gold nanoparticles loaded with methotrexate for cancer treatment. From synthesis to in vitro studies on neuroblastoma cell lines
Salamone, Ta; Rutigliano, L; Pennacchi, B; Cerra, S; Matassa, R; Nottola, S; Sciubba, F; Battocchio, C; Marsotto, M; Del Giudice, A; Chumakov, A; Davydok, A; Grigorian, S; Canettieri, G; Agostinelli, E; Fratoddi, I. - 01a Articolo in rivista
paper: JOURNAL OF COLLOID AND INTERFACE SCIENCE (San Diego: Elsevier Drive:Orlando, FL: Academic Press Incorporated) pp. 264-278 - issn: 0021-9797 - wos: WOS:001033080200001 (3) - scopus: 2-s2.0-85163213065 (3)

11573/1658043 - 2022 - Opposite effect of thyroid hormones on oxidative stress and on mitochondrial respiration in COVID-19 patients
De Vitis, Claudia; Capalbo, Carlo; Torsello, Alessandra; Napoli, Christian; Salvati, Valentina; Loffredo, Chiara; Blandino, Giovanni; Piaggio, Giulia; Auciello, Francesca Romana; Pelliccia, Flaminia; Salerno, Gerardo; Simmaco, Maurizio; Di Magno, Laura; Canettieri, Gianluca; Coluzzi, Flaminia; Mancini, Rita; Rocco, Monica; Sciacchitano, Salvatore - 01a Articolo in rivista
paper: ANTIOXIDANTS (Basel: MDPI) pp. 1-22 - issn: 2076-3921 - wos: WOS:000872096700001 (6) - scopus: 2-s2.0-85140491097 (6)

11573/1660747 - 2022 - Discovery of novel human lactate dehydrogenase inhibitors: Structure-based virtual screening studies and biological assessment
Di Magno, L; Coluccia, A; Bufano, M; Ripa, S; La Regina, G; Nalli, M; Di Pastena, F; Canettieri, G; Silvestri, R; Frati, L - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 114605- - issn: 0223-5234 - wos: WOS:000834164000003 (4) - scopus: 2-s2.0-85134696311 (4)

11573/1660745 - 2022 - The Mechanism of Action of Biguanides: New Answers to a Complex Question
Di Magno, L; Di Pastena, F; Bordone, R; Coni, S; Canettieri, G - 01g Articolo di rassegna (Review)
paper: CANCERS (Basel: MDPI) pp. 3220- - issn: 2072-6694 - wos: WOS:000823881900001 (12) - scopus: 2-s2.0-85133129147 (12)

11573/1655666 - 2022 - A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma
Petroni, Marialaura; Fabretti, Francesca; Di Giulio, Stefano; Nicolis Di Robilant, Vittoria; La Monica, Veronica; Moretti, Marta; Belardinilli, Francesca; Bufalieri, Francesca; Coppa, Anna; Paci, Paola; Corsi, Alessandro; De Smaele, Enrico; Coni, Sonia; Canettieri, Gianluca; Di Marcotullio, Lucia; Wang, Zhao‐Qi; Giannini, Giuseppe - 01a Articolo in rivista
paper: NEUROPATHOLOGY & APPLIED NEUROBIOLOGY (Oxford England: Blackwell Science) pp. - - issn: 1365-2990 - wos: WOS:000837995000001 (3) - scopus: 2-s2.0-85137005708 (3)

11573/1664745 - 2022 - Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor
Puxeddu, Michela; Wu, Jianchao; Bai, Ruoli; D’Ambrosio, Michele; Nalli, Marianna; Coluccia, Antonio; Manetto, Simone; Ciogli, Alessia; Masci, Domiziana; Urbani, Andrea; Fionda, Cinzia; Coni, Sonia; Bordone, Rosa; Canettieri, Gianluca; Bigogno, Chiara; Dondio, Giulio; Hamel, Ernest; Liu, Te; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 15805-15818 - issn: 0022-2623 - wos: WOS:000888017600001 (13) - scopus: 2-s2.0-85142634063 (12)

11573/1652233 - 2022 - Bovine serum amine oxidase and polyamine analogues: chemical synthesis and biological evaluation integrated with molecular docking and 3-D QSAR studies
Ragno, Rino; Anna, Minarini; Proia, Eleonora; Antonini, Lorenzo; Andrea, Milelli; Vincenzo, Tumiatti; Marco, Fiore; Fino, Pasquale; Rutigliano, Lavinia; Fioravanti, Rossella; Tahara, Tomoaki; Pacella, Elena; Greco, Antonio; Canettieri, Gianluca; Maria Luisa Di Paolo, ; Agostinelli, Enzo - 01a Articolo in rivista
paper: JOURNAL OF CHEMICAL INFORMATION AND MODELING (AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036) pp. 3910-3927 - issn: 1549-9596 - wos: WOS:000844671100001 (0) - scopus: 2-s2.0-85136242905 (0)

11573/1613555 - 2022 - Induction of Pro-Fibrotic CLIC4 in Dermal Fibroblasts by TGF-β/Wnt3a Is Mediated by GLI2 Upregulation
Wasson, C. W.; Caballero-Ruiz, B.; Gillespie, J.; Derrett-Smith, E.; Mankouri, J.; Denton, C. P.; Canettieri, G.; Galdo, N. A. R. -D.; Del Galdo, F. - 01a Articolo in rivista
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 530- - issn: 2073-4409 - wos: WOS:000756752400001 (3) - scopus: 2-s2.0-85123832912 (5)

11573/1546777 - 2021 - Specific Protein 1 and p53 Interplay Modulates the Expression of the KCTD-Containing Cullin3 Adaptor Suppressor of Hedgehog 2
Angrisani, A.; Di Fiore, A.; Di Trani, C. A.; Fonte, S.; Petroni, M.; Lospinoso Severini, L.; Bordin, F.; Belloni, L.; Ferretti, E.; Canettieri, G.; Moretti, M.; De Smaele, E. - 01a Articolo in rivista
paper: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. 1-16 - issn: 2296-634X - wos: WOS:000642096200001 (4) - scopus: 2-s2.0-85104623989 (4)

11573/1571355 - 2021 - Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function
Coni, Sonia; Falconio, Federica A; Marzullo, Marta; Munafò, Marzia; Zuliani, Benedetta; Mosti, Federica; Fatica, Alessandro; Ianniello, Zaira; Bordone, Rosa; Macone, Alberto; Agostinelli, Enzo; Perna, Alessia; Matkovic, Tanja; Sigrist, Stephan; Silvestri, Gabriella; Canettieri, Gianluca; Ciapponi, Laura - 01a Articolo in rivista
paper: ELIFE (Cambridge: eLife Sciences Publications) pp. - - issn: 2050-084X - wos: WOS:000696095100001 (7) - scopus: 2-s2.0-85116196697 (8)

11573/1569898 - 2021 - A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors
Di Giulio, Stefano; Colicchia, Valeria; Pastorino, Fabio; Pedretti, Flaminia; Fabretti, Francesca; Nicolis Di Robilant, Vittoria; Ramponi, Valentina; Scafetta, Giorgia; Moretti, Marta; Licursi, Valerio; Belardinilli, Francesca; Peruzzi, Giovanna; Infante, Paola; Goffredo, Bianca Maria; Coppa, Anna; Canettieri, Gianluca; Bartolazzi, Armando; Ponzoni, Mirco; Giannini, Giuseppe; Petroni, Marialaura - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. - - issn: 0950-9232 - wos: WOS:000694774500002 (15) - scopus: 2-s2.0-85118235580 (15)

11573/1569360 - 2021 - Enzymatic spermine metabolites induce apoptosis associated with increase of p53, caspase-3 and miR-34a in both neuroblastoma cells, SJNKP and the N-Myc-amplified form IMR5
Kanamori, Yuta; Finotti, Alessia; Di Magno, Laura; Canettieri, Gianluca; Tahara, Tomoaki; Timeus, Fabio; Greco, Antonio; Tirassa, Paola; Gasparello, Jessica; Fino, Pasquale; Di Liegro, Carlo Maria; Proia, Patrizia; Schiera, Gabriella; Di Liegro, Italia; Gambari, Roberto; Agostinelli, Enzo - 01a Articolo in rivista
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 1950- - issn: 2073-4409 - wos: WOS:000688873300001 (8) - scopus: 2-s2.0-85115044573 (9)

11573/1613271 - 2021 - Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoids
Lepore Signorile, M.; Grossi, V.; Di Franco, S.; Forte, G.; Disciglio, V.; Fasano, C.; Sanese, P.; De Marco, K.; Susca, F. C.; Mangiapane, L. R.; Nicotra, A.; Di Carlo, G.; Dituri, F.; Giannelli, G.; Ingravallo, G.; Canettieri, G.; Stassi, G.; Simone, C. - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000635208800001 (11) - scopus: 2-s2.0-85103476406 (11)

11573/1447549 - 2021 - Downregulation of miR-326 and its host gene β-arrestin1 induces pro survival activity of E2F1 and promotes medulloblastoma growth
Miele, Evelina; Po, Agnese; Mastronuzzi, Angela; Carai, Andrea; Besharat, Zein Mersini; Pediconi, Natalia; Abballe, Luana; Catanzaro, Giuseppina; Sabato, Claudia; De Smaele, Enrico; Canettieri, Gianluca; Di Marcotullio, Lucia; Vacca, Alessandra; Mai, Antonello; Levrero, Massimo; Pfister, Stefan M; Kool, Marcel; Giangaspero, Felice; Locatelli, Franco; Ferretti, Elisabetta - 01a Articolo in rivista
paper: MOLECULAR ONCOLOGY (Amsterdam : Elsevier Science) pp. - - issn: 1574-7891 - wos: WOS:000603687900001 (8) - scopus: 2-s2.0-85098446777 (8)

11573/1399216 - 2020 - Clinical Multigene Panel Sequencing Identifies Distinct Mutational Association Patterns in Metastatic Colorectal Cancer
Belardinilli, Francesca; Capalbo, Carlo; Malapelle, Umberto; Pisapia, Pasquale; Raimondo, Domenico; Milanetti, Edoardo; Mahdavian, Yasaman; Liccardi, Carlotta; Paci, Paola; Sibilio, Pasquale; Pepe, Francesco; Bonfiglio, Caterina; Mezi, Silvia; Magri, Valentina; Coppa, Anna; Nicolussi, Arianna; Gradilone, Angela; Petroni, Marialaura; Di Giulio, Stefano; Fabretti, Francesca; Infante, Paola; Coni, Sonia; Canettieri, Gianluca; Troncone, Giancarlo; Giannini, Giuseppe - 01a Articolo in rivista
paper: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. - - issn: 2234-943X - wos: WOS:000536940500001 (10) - scopus: 2-s2.0-85085205712 (10)

11573/1384478 - 2020 - The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i
Bufalieri, F.; Caimano, M.; Severini, L. L.; Basili, I.; Paglia, F.; Sampirisi, L.; Loricchio, E.; Petroni, M.; Canettieri, G.; Santoro, A.; D'angelo, L.; Infante, P.; Di Marcotullio, L. - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. 321- - issn: 2072-6694 - wos: WOS:000522477300067 (41) - scopus: 2-s2.0-85079068523 (40)

11573/1471575 - 2020 - Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation
Coni, S.; Serrao, S. M.; Yurtsever, Z. N.; Di Magno, L.; Bordone, R.; Bertani, C.; Licursi, V.; Ianniello, Z.; Infante, P.; Moretti, M.; Petroni, M.; Guerrieri, F.; Fatica, A.; Macone, A.; De Smaele, E.; Di Marcotullio, L.; Giannini, G.; Maroder, M.; Agostinelli, E.; Canettieri, G. - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000597627300001 (38) - scopus: 2-s2.0-85097416564 (40)

11573/1364966 - 2020 - Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module
Di Magno, L.; Manni, S.; Di Pastena, F.; Coni, S.; Macone, A.; Cairoli, S.; Sambucci, M.; Infante, P.; Moretti, M.; Petroni, M.; Nicoletti, C.; Capalbo, C.; De Smaele, E.; Di Marcotullio, L.; Giannini, G.; Battistini, L.; Goffredo, B. M.; Iorio, E.; Agostinelli, E.; Maroder, M.; Canettieri, G. - 01a Articolo in rivista
paper: CELL REPORTS (Elsevier B.V. Cambridge MA: Cell Press) pp. 1735-1752 - issn: 2211-1247 - wos: WOS:000513920800008 (35) - scopus: 2-s2.0-85079335561 (35)

11573/1451071 - 2020 - Sulfonamide inhibitors of beta-catenin signaling as anticancer agents with different output on c-Myc
Di Magno, Laura; Di Pastena, Fiorella; Puxeddu, Michela; La Regina, Giuseppe; Coluccia, Antonio; Ciogli, Alessia; Manetto, Simone; Maroder, Marella; Canettieri, Gianluca; Silvestri, Romano; Nalli, Marianna - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 2264-2268 - issn: 1860-7179 - wos: WOS:000577594900001 (5) - scopus: 2-s2.0-85092511066 (5)

11573/1446421 - 2020 - Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response
Giuli, Maria Valeria; Diluvio, Giulia; Giuliani, Eugenia; Franciosa, Giulia; Di Magno, Laura; Pignataro, Maria Gemma; Tottone, Luca; Nicoletti, Carmine; Besharat, Zein Mersini; Peruzzi, Giovanna; Pelullo, Maria; Palermo, Rocco; Canettieri, Gianluca; Talora, Claudio; D'amati, Giulia; Bellavia, Diana; Screpanti, Isabella; Checquolo, Saula - 01a Articolo in rivista
paper: ONCOGENESIS (London Nature Publishing Group) pp. 1-16 - issn: 2157-9024 - wos: WOS:000579242100001 (14) - scopus: 2-s2.0-85092794807 (13)

11573/1381934 - 2020 - Aged garlic extract and its constituent, S-allyl-L-cysteine, induce the apoptosis of neuroblastoma cancer cells due to mitochondrial membrane depolarization
Kanamori, Yuta; Via, Lisa Dalla; Macone, Alberto; Canettieri, Gianluca; Greco, Antonio; Toninello, Antonio; Agostinelli, Enzo - 01a Articolo in rivista
paper: EXPERIMENTAL AND THERAPEUTIC MEDICINE (Athens: Spandidos Publications) pp. 1511-1521- - issn: 1792-0981 - wos: WOS:000508876600093 (20) - scopus: (0)

11573/1456804 - 2020 - Nanotechnology-based strategies to develop new anticancer therapies
Magro, M.; Venerando, A.; Macone, A.; Canettieri, G.; Agostinelli, E.; Vianello, F. - 01a Articolo in rivista
paper: BIOMOLECULES (Basel: MDPI) pp. 735- - issn: 2218-273X - wos: WOS:000545013700072 (27) - scopus: 2-s2.0-85084478698 (32)

11573/1210601 - 2019 - Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation
Antonucci, Laura; Di Magno, Laura; D'amico, Davide; Manni, Simona; Serrao, Silvia Maria; Di Pastena, Fiorella; Bordone, Rosa; Yurtsever, Zuleyha Nihan; Caimano, Miriam; Petroni, Marialaura; Giorgi, Alessandra; Schininà, Maria Eugenia; Yates Iii, John R; Di Marcotullio, Lucia; De Smaele, Enrico; Checquolo, Saula; Capalbo, Carlo; Agostinelli, Enzo; Maroder, Marella; Coni, Sonia; Canettieri, Gianluca - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF ONCOLOGY (National Hellenic Research Foundation:48 Vas Constatinou Avenue, Athens 11635 Greece:011 30 1 7241505, Fax: 011 30 1 7241505Editore attuale:PROFESSOR D A SPANDIDOS, 1, S MERKOURI ST, EDITORIAL OFFICE,, ATHENS, GREECE, 116 35. Editore precedente:Editorial Academy of the International Journal of Oncology.) pp. 505-514 - issn: 1019-6439 - wos: WOS:000454923900009 (25) - scopus: 2-s2.0-85058877986 (25)

11573/1304369 - 2019 - ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP
Bufalieri, F.; Infante, P.; Bernardi, F.; Caimano, M.; Romania, P.; Moretti, M.; Lospinoso Severini, L.; Talbot, J.; Melaiu, O.; Tanori, M.; Di Magno, L.; Bellavia, D.; Capalbo, C.; Puget, S.; De Smaele, E.; Canettieri, G.; Guardavaccaro, D.; Busino, L.; Peschiaroli, Angelo; Pazzaglia, S.; Giannini, G.; Melino, G.; Locatelli, F.; Gulino, A.; Ayrault, O.; Fruci, D.; Di Marcotullio, L. - 01a Articolo in rivista
paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. 1-15 - issn: 2041-1723 - wos: WOS:000476877400003 (35) - scopus: 2-s2.0-85069646549 (36)

11573/1224164 - 2019 - A simplified genomic profiling approach predicts outcome in metastatic colorectal cancer
Capalbo, Carlo; Belardinilli, Francesca; Raimondo, Domenico; Milanetti, Edoardo; Malapelle, Umberto; Pisapia, Pasquale; Magri, Valentina; Prete, Alessandra; Pecorari, Silvia; Colella, Mariarosaria; Coppa, Anna; Bonfiglio, Caterina; Nicolussi, Arianna; Valentini, Virginia; Tessitore, Alessandra; Cardinali, Beatrice; Petroni, Marialaura; Infante, Paola; Santoni, Matteo; Filetti, Marco; Colicchia, Valeria; Paci, Paola; Mezi, Silvia; Longo, Flavia; Cortesi, Enrico; Marchetti, Paolo; Troncone, Giancarlo; Bellavia, Diana; Canettieri, Gianluca; Giannini, Giuseppe - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000460747200021 (9) - scopus: 2-s2.0-85061991505 (9)

11573/1223718 - 2019 - Drug design and synthesis of first in class PDZ1 targeting NHERF1 inhibitors as anticancer agents
Coluccia, A.; La Regina, G.; Naccarato, V.; Nalli, M.; Orlando, V.; Biagioni, S.; De Angelis, M. L.; Baiocchi, M.; Gautier, C.; Gianni, S.; Di Pastena, F.; Di Magno, L.; Canettieri, G.; Coluccia, A. M. L.; Silvestri, R. - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 499-503 - issn: 1948-5875 - wos: WOS:000464767700019 (13) - scopus: 2-s2.0-85064264813 (13)

11573/1338499 - 2019 - Polyamine metabolism as a therapeutic target in hedgehog-driven basal cell carcinoma and medulloblastoma
Coni, Sonia; Di Magno, Laura; Serrao, Silvia Maria; Kanamori, Yuta; Agostinelli, Enzo; Canettieri, Gianluca - 01a Articolo in rivista
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 150- - issn: 2073-4409 - wos: WOS:000460896000072 (16) - scopus: 2-s2.0-85071164976 (15)

11573/1338512 - 2019 - Design, synthesis and biological evaluation of PDZ1 targeting NHERF1 inhibitors as anticancer agents
La Regina, G.; Naccarato, V.; Masci, D.; Puxeddu, M.; Bufano, M.; Nalli, M.; Coluccia, A.; Orlando, V.; Canettieri, G.; Gianni, S.; Silvestri, R. - 04f Poster
conference: XXVI National Meeting in Medicinal Chemistry - XII Young Medicinal Chemists’ Symposium (Milano)
book: Abstract Book - ()

11573/1273189 - 2019 - Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells
Ohkubo, S; Mancinelli, R; Miglietta, S; Cona, A; Angelini, R; Canettieri, G; Spandidos, Da; Gaudio, E; Agostinelli, E. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF ONCOLOGY (National Hellenic Research Foundation:48 Vas Constatinou Avenue, Athens 11635 Greece:011 30 1 7241505, Fax: 011 30 1 7241505Editore attuale:PROFESSOR D A SPANDIDOS, 1, S MERKOURI ST, EDITORIAL OFFICE,, ATHENS, GREECE, 116 35. Editore precedente:Editorial Academy of the International Journal of Oncology.) pp. 2080-2094 - issn: 1019-6439 - wos: WOS:000477432000015 (17) - scopus: 2-s2.0-85064884111 (16)

11573/1343151 - 2019 - SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors
Petroni, Marialaura; Sahùn Roncero, Maria; Ramponi, Valentina; Fabretti, Francesca; Nicolis Di Robilant, Vittoria; Moretti, Marta; Alfano, Vincenzo; Corsi, Alessandro; De Panfilis, Simone; Giubettini, Maria; Di Giulio, Stefano; Capalbo, Carlo; Belardinilli, Francesca; Coppa, Anna; Sardina, Francesca; Colicchia, Valeria; Pedretti, Flaminia; Infante, Paola; Cardinali, Beatrice; Tessitore, Alessandra; Canettieri, Gianluca; De Smaele, Enrico; Giannini, Giuseppe - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000508896900014 (4) - scopus: 2-s2.0-85077063979 (4)

11573/1338842 - 2019 - KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2
Spiombi, Eleonora; Angrisani, Annapaola; Fonte, Simone; De Feudis, Giuseppina; Fabretti, Francesca; Cucchi, Danilo; Izzo, Mariapaola; Infante, Paola; Miele, Evelina; Po, Agnese; Di Magno, Laura; Magliozzi, Roberto; Guardavaccaro, Daniele; Maroder, Marella; Canettieri, Gianluca; Giannini, Giuseppe; Ferretti, Elisabetta; Gulino, Alberto; Di Marcotullio, Lucia; Moretti, Marta; De Smaele, Enrico - 01a Articolo in rivista
paper: ONCOGENESIS (London Nature Publishing Group) pp. 64- - issn: 2157-9024 - wos: WOS:000494423700001 (20) - scopus: 2-s2.0-85074354238 (20)

11573/1560466 - 2018 - Targeting metabolic vulnerabilities to treat Shh medulloblastoma
Di Magno, L; Manni, S; Di Pastena, F; Coni, S; Serrao, Sm; Agostinelli, E; Canettieri, G - 01h Abstract in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (D. A. Spandidos. Athens) pp. S34-S34 - issn: 1107-3756 - wos: WOS:000452818300121 (0) - scopus: (0)

11573/1085264 - 2018 - Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis
Infante, Paola; Faedda, Roberta; Bernardi, Flavia; Bufalieri, Francesca; Lospinoso Severini, Ludovica; Alfonsi, Romina; Mazzà, Daniela; Siler, Mariangela; Coni, Sonia; Po, Agnese; Petroni, Marialaura; Ferretti, Elisabetta; Mori, Mattia; De Smaele, Enrico; Canettieri, Gianluca; Capalbo, Carlo; Maroder, Marella; Screpanti, Isabella; Kool, Marcel; Pfister, Stefan M.; Guardavaccaro, Daniele; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. ...-... - issn: 2041-1723 - wos: WOS:000426899000002 (47) - scopus: 2-s2.0-85044632076 (50)

11573/1178443 - 2018 - The antioxidant, aged garlic extract, exerts cytotoxic effects on wild-type and multidrug-resistant human cancer cells by altering mitochondrial permeability
Ohkubo, Shinji; Via, Lisa Dalla; Grancara, Silvia; Kanamori, Yuta; García-Argáez, Aída Nelly; Canettieri, Gianluca; Arcari, Paolo; Toninello, Antonio; Agostinelli, Enzo - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF ONCOLOGY (National Hellenic Research Foundation:48 Vas Constatinou Avenue, Athens 11635 Greece:011 30 1 7241505, Fax: 011 30 1 7241505Editore attuale:PROFESSOR D A SPANDIDOS, 1, S MERKOURI ST, EDITORIAL OFFICE,, ATHENS, GREECE, 116 35. Editore precedente:Editorial Academy of the International Journal of Oncology.) pp. 1257-1268 - issn: 1019-6439 - wos: WOS:000440583100029 (9) - scopus: 2-s2.0-85052016141 (9)

11573/1602341 - 2017 - Corrigendum: Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma
Coni, S.; Mancuso, A. B.; Di Magno, L.; Sdruscia, G.; Manni, S.; Serrao, S. M.; Rotili, D.; Spiombi, E.; Bufalieri, F.; Petroni, M.; Kusio-Kobialka, M.; De Smaele, E.; Ferretti, E.; Capalbo, C.; Mai, A.; Niewiadomski, P.; Screpanti, I.; Di Marcotullio, L.; Canettieri, G. - 01b Commento, Erratum, Replica e simili
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000399974300001 (5) - scopus: 2-s2.0-85068766477 (4)

11573/1560468 - 2017 - Targeting Gli acetylation in Shh-medulloblastoma: A successful preclinical approach
Coni, S; Di Magno, L; Mancuso, Ab; Sdruscia, G; Manni, S; Serrao, Sm; Di Marcotullio, L; De Smaele, E; Ferretti, E; Canettieri, G - 01h Abstract in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (D. A. Spandidos. Athens) pp. S26-S26 - issn: 1107-3756 - wos: WOS:000411659300088 (0) - scopus: (0)

11573/946157 - 2017 - Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.
Coni, Sonia; Mancuso, Anna Barbara; Di Magno, L; Sdruscia, Giulia; Manni, Simona; Serrao, Silvia Maria; Rotili, Dante; Spiombi, Eleonora; Bufalieri, Francesca; Petroni, Marialaura; Kusio Kobialka, M; De Smaele, Enrico; Ferretti, Elisabetta; Capalbo, Carlo; Mai, Antonello; Niewiadomski, P; Screpanti, Isabella; Di Marcotullio, Lucia; Canettieri, Gianluca - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 44079- - issn: 2045-2322 - wos: WOS:000396136700001 (54) - scopus: 2-s2.0-85014895304 (54)

11573/1020037 - 2017 - Targeting class I histone deacetylases by the novel small molecule inhibitor 4SC-202 blocks oncogenic hedgehog-GLI signaling and overcomes smoothened inhibitor resistance
Gruber, Wolfgang; Peer, Elisabeth; Elmer, Dominik P; Sternberg, Christina; Tesanovic, Suzana; Del Burgo, Pedro; Coni, Sonia; Canettieri, Gianluca; Neureiter, Daniel; Bartz, René; Kohlhof, Hella; Vitt, Daniel; Aberger, Fritz - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF CANCER (Hoboken N.J.: Wiley New York NY: Wiley-Liss) pp. - - issn: 0020-7136 - wos: WOS:000419362200011 (39) - scopus: 2-s2.0-85040129209 (40)

11573/1024175 - 2017 - β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells
Miele, Evelina; Po, Agnese; Begalli, Federica; Antonucci, Laura; Mastronuzzi, Angela; Marras, Carlo Efisio; Carai, Andrea; Cucchi, Danilo; Abballe, Luana; Besharat, Zein Mersini; Catanzaro, Giuseppina; Infante, Paola; Di Marcotullio, Lucia; Canettieri, Gianluca; De Smaele, Enrico; Screpanti, Isabella; Locatelli, Franco; Ferretti, Elisabetta - 01a Articolo in rivista
paper: BMC CANCER (London: BioMed Central, [2001]-) pp. 488- - issn: 1471-2407 - wos: WOS:000405865300002 (52) - scopus: 2-s2.0-85024120271 (54)

11573/952694 - 2017 - Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma
Po, Agnese; Silvano, Marianna; Miele, Evelina; Capalbo, Carlo; Eramo, A.; Salvati, V.; Todaro, M.; Besharat, Zein Mersini; Catanzaro, Giuseppina; Cucchi, Danilo; Coni, Sonia; Di Marcotullio, Lucia; Canettieri, Gianluca; Vacca, Alessandra; Stassi, G.; De Smaele, Enrico; Tartaglia, M.; Screpanti, Isabella; De Maria, R.; Ferretti, Elisabetta - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. - - issn: 0950-9232 - wos: WOS:000407246200011 (79) - scopus: 2-s2.0-85016980676 (82)

11573/892827 - 2016 - Translating Hedgehog in Cancer: Controlling Protein Synthesis
D'amico, Davide; Canettieri, Gianluca - 01a Articolo in rivista
paper: TRENDS IN MOLECULAR MEDICINE (London: Elsevier Science, 2001-) pp. 851-862-862 - issn: 1471-4914 - wos: WOS:000385324900006 (12) - scopus: 2-s2.0-84994138699 (13)

11573/863407 - 2016 - The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint
Di Magno, Laura; Basile, Alessio; Coni, Sonia; Manni, Simona; Sdruscia, Giulia; D'amico, Davide; Antonucci, Laura; Infante, Paola; De Smaele, Enrico; Cucchi, Danilo; Ferretti, Elisabetta; Di Marcotullio, Lucia; Screpanti, Isabella; Canettieri, Gianluca - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 9538-9549 - issn: 1949-2553 - wos: WOS:000375618100081 (38) - scopus: 2-s2.0-84961627529 (39)

11573/901391 - 2016 - Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype
Infante, Paola; Alfonsi, Romina; Ingallina, Cinzia; Quaglio, Deborah; Ghirga, Francesca; D'acquarica, Ilaria; Bernardi, Flavia; Di Magno, Laura; Canettieri, Gianluca; Screpanti, Isabella; Gulino, Alberto; Botta, Bruno; Mori, Mattia; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000387968100003 (50) - scopus: 2-s2.0-84992361773 (49)

11573/808763 - 2015 - Determination of acetylation of the Gli transcription factors
Coni, Sonia; Di Magno, Laura; Canettieri, Gianluca - 02a Capitolo o Articolo
book: Hedgehog signaling protocols - (978-1-4939-2771-5; 978-1-4939-2772-2)

11573/808783 - 2015 - Non-canonical Hedgehog/ampk-mediated control of polyamine metabolism supports neuronal and medulloblastoma cell growth
D'amico, Davide; Antonucci, Laura; Di Magno, Laura; Coni, Sonia; Sdruscia, Giulia; Macone, Alberto; Miele, Evelina; Infante, Paola; Di Marcotullio, Lucia; De Smaele, Enrico; Ferretti, Elisabetta; Ciapponi, Laura; Giangaspero, Felice; John, R. Yates Iii; Agostinelli, Enzo; Cardinali, Beatrice; Screpanti, Isabella; Gulino, Alberto; Canettieri, Gianluca - 01a Articolo in rivista
paper: DEVELOPMENTAL CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 21-35 - issn: 1534-5807 - wos: WOS:000363076000008 (56) - scopus: 2-s2.0-84945252145 (57)

11573/808871 - 2015 - Digging a hole under Hedgehog: Downstream inhibition as an emerging anticancer strategy
Di Magno, Laura; Coni, Sonia; Di Marcotullio, Lucia; Canettieri, Gianluca - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (Elsevier Scientific Publ. Co.) pp. 62-72 - issn: 0304-419X - wos: WOS:000360776200006 (50) - scopus: 2-s2.0-84934937938 (55)

11573/649688 - 2015 - Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors
Infante, Paola; Mori, Mattia; Alfonsi, Romina; Ghirga, Francesca; Federica, Aiello; Toscano, Sara; Ingallina, Cinzia; Mariangela, Siler; Cucchi, Danilo; Po, Agnese; Miele, Evelina; Davide, D’Amico; Canettieri, Gianluca; De Smaele, Enrico; Ferretti, Elisabetta; Screpanti, Isabella; Gloria Uccello, Barretta; Maurizio, Botta; Botta, Bruno; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 200-217 - issn: 0261-4189 - wos: WOS:000347878900008 (146) - scopus: 2-s2.0-84921293370 (147)

11573/543173 - 2014 - CNBP regulates wing development in Drosophila melanogaster by promoting IRES-dependent translation of dMyc
Antonucci, Laura; D'amico, Davide; Di Magno, Laura; Coni, Sonia; Di Marcotullio, Lucia; Beatrice, Cardinali; Gulino, Alberto; Ciapponi, Laura; Canettieri, Gianluca - 01a Articolo in rivista
paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 434-439 - issn: 1538-4101 - wos: WOS:000332833400019 (16) - scopus: 2-s2.0-84896873986 (17)

11573/648414 - 2014 - Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth
Di Magno, Laura; Daniela, Manzi; D'amico, Davide; Coni, Sonia; Macone, Alberto; Infante, Paola; Di Marcotullio, Lucia; De Smaele, Enrico; Ferretti, Elisabetta; Screpanti, Isabella; Agostinelli, Enzo; Gulino, Alberto; Canettieri, Gianluca - 01a Articolo in rivista
paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 3404-3413 - issn: 1538-4101 - wos: WOS:000348313100013 (38) - scopus: 2-s2.0-84915795126 (39)

11573/557496 - 2014 - Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38α modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A
Germani, Aldo; Antonio, Matrone; Grossi, Valentina; Alessia, Peserico; Paola, Sanese; Micaela, Liuzzi; Palermo, Rocco; Stefania, Murzilli; Campese, Antonio Francesco; Giuseppe, Ingravallo; Canettieri, Gianluca; Tugsan, Tezil; Cristiano, Simone - 01a Articolo in rivista
paper: CANCER LETTERS (Elsevier Science Ireland Limited:PO Box 85, Limerick Ireland:011 353 61 709600, 011 353 61 61944, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 353 61 709114) pp. 110-118 - issn: 0304-3835 - wos: WOS:000331688700013 (43) - scopus: 2-s2.0-84893131728 (44)

11573/649690 - 2014 - Yin-Yang strands of PCAF/Hedgehog axis in cancer control
Infante, Paola; Canettieri, Gianluca; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: TRENDS IN MOLECULAR MEDICINE (London: Elsevier Science, 2001-) pp. 416-418 - issn: 1471-4914 - wos: WOS:000340303300002 (13) - scopus: 2-s2.0-84905115865 (12)

11573/543166 - 2013 - Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy
Coni, Sonia; Antonucci, Laura; D'amico, Davide; Di Magno, Laura; Infante, Paola; De Smaele, Enrico; Giannini, Giuseppe; Di Marcotullio, Lucia; Screpanti, Isabella; Gulino, Alberto; Canettieri, Gianluca - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e65718- - issn: 1932-6203 - wos: WOS:000321099000097 (59) - scopus: 2-s2.0-84878804952 (61)

11573/527314 - 2013 - microRNA-17-92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1
Garg, Neha; Po, Agnese; Miele, Evelina; Campese, Antonio Francesco; Begalli, Federica; Marianna, Silvano; Infante, Paola; Capalbo, Carlo; De Smaele, Enrico; Canettieri, Gianluca; Di Marcotullio, Lucia; Screpanti, Isabella; Ferretti, Elisabetta; Gulino, Alberto - 01a Articolo in rivista
paper: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 2819-2832 - issn: 0261-4189 - wos: WOS:000326504900006 (54) - scopus: 2-s2.0-84887046837 (54)

11573/527250 - 2013 - PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress
Mazza, Daniele; Infante, Paola; Colicchia, Valeria; Greco, Azzura; Alfonsi, Romina; M., Siler; Antonucci, Laura; Po, Agnese; De Smaele, Enrico; Ferretti, Elisabetta; Capalbo, Carlo; Bellavia, Diana; Canettieri, Gianluca; Giannini, Giuseppe; Screpanti, Isabella; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
paper: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 1688-1697 - issn: 1350-9047 - wos: WOS:000327010600012 (71) - scopus: 2-s2.0-84887619992 (80)

11573/477270 - 2012 - CCAAT/enhancer-binding proteins are key regulators of human type two deiodinase expression in a placenta cell line
Canettieri, Gianluca; Santaguida, Maria Giulia; Antonucci, Laura; M. D., Guardia; A., Franchi; Coni, Sonia; Gulino, Alberto; Centanni, Marco - 01a Articolo in rivista
paper: ENDOCRINOLOGY (Endocrine Society / Maryland:8401 Connecticut Avenue, Suite 900:Chevy Chase, MD 20815:(301)941-0200, (301)941-0200, (301)941-0232, EMAIL: journals@endo-society.org, INTERNET: http://www.endo.society.org, Fax: (301)941-0259) pp. 4030-4038 - issn: 0013-7227 - wos: WOS:000306652400048 (7) - scopus: 2-s2.0-84864390244 (7)

11573/444530 - 2012 - Hedgehog/Gli Control by Ubiquitination/Acetylation Interplay
Gulino, Alberto; Di Marcotullio, Lucia; Canettieri, Gianluca; De Smaele, Enrico; Screpanti, Isabella - 02a Capitolo o Articolo
book: Hedgehog Signaling - (9780123946225)

11573/434259 - 2012 - Acetylation controls Notch3 stability and function in T-cell leukemia
Palermo, Rocco; Checquolo, Saula; A., Giovenco; Grazioli, Paola; Kumar, Vivek; Campese, Antonio Francesco; Giorgi, Alessandra; Napolitano, Maddalena; Canettieri, Gianluca; G., Ferrara; Schinina', Maria Eugenia; Maroder, Marella; Frati, Luigi; Gulino, Alberto; Vacca, Alessandra; Screpanti, Isabella - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 3807-3817 - issn: 0950-9232 - wos: WOS:000307924900007 (48) - scopus: 2-s2.0-84865202947 (50)

11573/377914 - 2011 - Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma
De Smaele, Enrico; Di Marcotullio, Lucia; Moretti, Marta; Pelloni, Marianna; Occhione, Maria Anna; Infante, Paola; Cucchi, Danilo; Greco, Azzura; Pietrosanti, Laura; J., Todorovic; Coni, Sonia; Canettieri, Gianluca; Ferretti, Elisabetta; R., Bei; Maroder, Marella; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: NEOPLASIA (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 374-385 - issn: 1522-8002 - wos: WOS:000289529400009 (76) - scopus: 2-s2.0-79952438480 (78)

11573/360864 - 2011 - Protected from the inside: Endogenous histone deacetylase inhibitors and the road to cancer
Di Marcotullio, Lucia; Canettieri, Gianluca; Infante, Paola; Greco, Azzura; Gulino, Alberto - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (Elsevier Scientific Publ. Co.) pp. 241-252 - issn: 0304-419X - wos: WOS:000289020200009 (42) - scopus: 2-s2.0-79951713773 (46)

11573/377915 - 2011 - Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal
Di Marcotullio, Lucia; Greco, Azzura; Mazza', Daniela; Canettieri, Gianluca; Pietrosanti, Laura; Infante, Paola; Coni, Sonia; Moretti, Marta; De Smaele, Enrico; Ferretti, Elisabetta; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 65-76 - issn: 0950-9232 - wos: WOS:000285959300006 (90) - scopus: 2-s2.0-78650983824 (93)

11573/229541 - 2010 - Turning off the switch in medulloblastoma. The inhibitory acetylation of an oncogene
Canettieri, Gianluca; Di Marcotullio, Lucia; Coni, Sonia; Greco, Azzura; Gulino, Alberto - 01m Editorial/Introduzione in rivista
paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 2047-2048 - issn: 1538-4101 - wos: WOS:000279148400003 (7) - scopus: 2-s2.0-77953598291 (7)

11573/401408 - 2010 - Histone deacetylase and Cullin3-REN KCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation
Canettieri, Gianluca; Di Marcotullio, Lucia; Greco, Azzura; Coni, Sonia; Antonucci, Laura; Infante, Paola; Pietrosanti, Laura; De Smaele, Enrico; Ferretti, Elisabetta; Miele, Evelina; Pelloni, Marianna; Giuseppina De, Simone; Emilia Maria, Pedone; Paola, Gallinari; Giorgi, Alessandra; Christian, Steinkuhler; Luigi, Vitagliano; Carlo, Pedone; Schinina', Maria Eugenia; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: NATURE CELL BIOLOGY (Nature America Incorporated:345 Park Avenue South, 6th Floor:New York, NY 10010:(888)331-6288, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: (212)689-9108) pp. 132-U91 - issn: 1465-7392 - wos: WOS:000274139400007 (280) - scopus: 2-s2.0-75949106376 (286)

11573/364193 - 2010 - Hedgehog controls neural stem cells through p53-independent regulation of Nanog
Po, Agnese; Ferretti, Elisabetta; Miele, Evelina; De Smaele, Enrico; Arianna, Paganelli; Canettieri, Gianluca; Coni, Sonia; Di Marcotullio, Lucia; Biffoni, Marco; Luca, Massimi; Concezio Di, Rocco; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
paper: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 2646-2658 - issn: 0261-4189 - wos: WOS:000280658900017 (183) - scopus: 2-s2.0-77955362243 (189)

11573/227363 - 2009 - TORCs/CRTCs: More than mere coincidence.
Canettieri, Gianluca; Coni, Sonia; Antonucci, Laura; Di Magno, L; Gulino, Alberto - 01a Articolo in rivista
paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 963-964 - issn: 1538-4101 - wos: WOS:000265593900004 (1) - scopus: 2-s2.0-65949094352 (1)

11573/228587 - 2009 - The coactivator CRTC1 promotes cell proliferation and transformation via AP-1
Canettieri, Gianluca; Coni, Sonia; Della Guardia, M.; Nocerino, V.; Antonucci, Laura; Di Magno, L. D.; Screaton, R.; Screpanti, Isabella; Giannini, Giuseppe; Gulino, Alberto - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 1445-1450 - issn: 0027-8424 - wos: WOS:000263074600030 (52) - scopus: 2-s2.0-60849118154 (52)

11573/230757 - 2008 - Activation of thyroid hormone is transcriptionally regulated by Epidermal Growth Factor in human placenta derived Jeg-3 cells.
Canettieri, Gianluca; Franchi, A; Guardia, Md; Morantte, I; Santaguida, Maria Giulia; Harney, Jw; Larsen, Pr; Centanni, Marco - 01a Articolo in rivista
paper: ENDOCRINOLOGY (Endocrine Society / Maryland:8401 Connecticut Avenue, Suite 900:Chevy Chase, MD 20815:(301)941-0200, (301)941-0200, (301)941-0232, EMAIL: journals@endo-society.org, INTERNET: http://www.endo.society.org, Fax: (301)941-0259) pp. 695-702 - issn: 0013-7227 - wos: WOS:000252506800033 (16) - scopus: 2-s2.0-38549128363 (18)

11573/362261 - 2008 - An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma
De Smaele, Enrico; C., Fragomeli; Ferretti, Elisabetta; Pelloni, Marianna; Po, Agnese; Canettieri, Gianluca; Coni, Sonia; Di Marcotullio, Lucia; Greco, Azzura; Moretti, Marta; C., Di Rocco; S., Pazzaglia; Maroder, Marella; Screpanti, Isabella; Giannini, Giuseppe; Gulino, Alberto - 01a Articolo in rivista
paper: NEOPLASIA (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 89-98 - issn: 1522-8002 - wos: WOS:000253614300009 (43) - scopus: 2-s2.0-38649132910 (44)

11573/233670 - 2006 - Thyroxine in goiter, Helicobacter pylori infection and chronic gastritis
Centanni, Marco; Gargano, L.; Canettieri, Gianluca; Viceconti, N.; Franchi, A.; Delle Fave, Gianfranco; Annibale, Bruno - 01a Articolo in rivista
paper: THE NEW ENGLAND JOURNAL OF MEDICINE (Boston: Massachusetts Medical Society) pp. 1787-1795 - issn: 0028-4793 - wos: WOS:000237077100004 (225) - scopus: 2-s2.0-33646096958 (269)

11573/145047 - 2005 - Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling
Canettieri, Gianluca; Seung Hoi, Koo; Rebecca, Berdeaux; Jose, Heredia; Susan, Hedrick; Xinmin, Zhang; Marc, Montminy - 01a Articolo in rivista
paper: CELL METABOLISM (CELL PRESS, Cambridge (MA) USA) pp. 331-338 - issn: 1550-4131 - wos: WOS:000233232700010 (56) - scopus: 2-s2.0-33645055091 (59)

11573/145048 - 2005 - Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues
X. M., Zhang; D. T., Odom; S. H., Koo; M. D., Conkright; Canettieri, Gianluca; J., Best; H. M., Chen; R., Jenner; E., Herbolsheimer; E., Jacobsen; S., Kadam; J. R., Ecker; B., Emerson; J. B., Hogenesch; T., Unterman; R. A., Young; M., Montminy - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 4459-4464 - issn: 0027-8424 - wos: WOS:000227854800044 (376) - scopus: 2-s2.0-20144379523 (812)

11573/503299 - 2004 - Meccansimi di controllo della funzione tiroidea
Andreoli, Mario; Canettieri, Gianluca - 02a Capitolo o Articolo
book: La Tiroide - (8849001029)

11573/503283 - 2004 - L'omeostasi tiroidea nella regolazione del codice epigenetico
Canettieri, Gianluca - 02a Capitolo o Articolo
book: La Tiroide - (8849001029)

11573/240710 - 2004 - Functional characterization of the CRE/TATA BOX unit of type 2 deiodinase gene promoter in a human choriocarcinoma cell line
Canettieri, Gianluca; Franchi, A; Sibilla, R; Guzmán, E; Centanni, Marco - 01a Articolo in rivista
paper: JOURNAL OF MOLECULAR ENDOCRINOLOGY (Pubblicata da: SOC ENDOCRINOLOGY, 22 APEX COURT, WOODLANDS, BRADLEY STOKE, BRISTOL, ENGLAND, BS32 4JT primo editore: Journal of Endocrinology Limited:17 18 Courtyard Woodlands, Bristol BS12 4NQ United Kingdom:011 44 117 9616046, EMAIL: sxa15@psu.edu, INTERNET: http://www.psu.edu, Fax: 011 44 117 9616071) pp. 51-58 - issn: 0952-5041 - wos: WOS:000223552100005 (17) - scopus: 2-s2.0-4444352547 (18)

11573/145049 - 2004 - The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector
Robert A., Screaton; Michael D., Conkright; Yoshiko, Katoh; Jennifer L., Best; Canettieri, Gianluca; Shawn, Jeffries; Ernesto, Guzman; Sherry, Niessen; R. D., Yates Jr; Hiroshi, Takemori; Mitsuhiro, Okamoto; Marc, Montminy - 01a Articolo in rivista
paper: CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 61-74 - issn: 0092-8674 - wos: WOS:000224292600009 (516) - scopus: 2-s2.0-5344228270 (532)

11573/143212 - 2003 - Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex.
Canettieri, Gianluca; Morantte, I; Guzmán, E; Asahara, H; Herzig, S; Anderson, Sd; Yates Jr, Rd; Montminy, M. - 01a Articolo in rivista
paper: NATURE STRUCTURAL BIOLOGY (Nature America Incorporated:345 Park Avenue South, 6th Floor:New York, NY 10010:(888)331-6288, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: (212)689-9108) pp. 175-181 - issn: 1072-8368 - wos: WOS:000181178500010 (173) - scopus: 2-s2.0-0037337748 (181)

11573/143211 - 2003 - cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.
Jhala, Us; Canettieri, Gianluca; Screaton, Ra; Kulkarni, Rn; Krajewski, S; Reed, J; Walker, J; Lin, X; White, M; Montminy, M. - 01a Articolo in rivista
paper: GENES & DEVELOPMENT (Cold Spring Harbor Laboratory:500 Sunnyside Boulevard:Woodbury, NY 11797:(800)843-4388, (516)422-4100, EMAIL: cshpress@cshl.org, INTERNET: http://www.cshl.org, Fax: (516)422-4097) pp. 1575-1580 - issn: 0890-9369 - wos: WOS:000183998600003 (467) - scopus: 2-s2.0-0038339191 (488)

11573/145051 - 2003 - TORCs: Transducers of regulated CREB activity
M. D., Conkright; Canettieri, Gianluca; R., Screaton; E., Guzman; L., Miraglia; J. B., Hogenesch; M., Montminy - 01a Articolo in rivista
paper: MOLECULAR CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 413-423 - issn: 1097-2765 - wos: WOS:000185050000015 (498) - scopus: 2-s2.0-0141922981 (521)

11573/254766 - 2003 - Increased serum inhibin B levels in postmenopausal women with altered thyroid function
N., Viceconti; S., Luisi; S., Nardo; L., Gargano; A., Franchi; R., Sibilla; Canettieri, Gianluca; F., Petraglia; Centanni, Marco - 01a Articolo in rivista
paper: HORMONE AND METABOLIC RESEARCH (Stuttgart Germany: Georg Thieme Verlag Stuttgart) pp. 498-501 - issn: 0018-5043 - wos: WOS:000185465200008 (1) - scopus: 2-s2.0-0141675045 (1)

11573/503512 - 2002 - Hormonal signaling and chromatin remodeling: histone acetylation and deacetylation mediated by cAMP
Canettieri, Gianluca - 04a Atto di comunicazione a congresso
conference: Signal transduction and neoplastic transformation in endocrine systems: molecular mechanisms and clinical aspects (Roma)

11573/254626 - 2002 - Reversible increase of serum activin A levels in women with Graves' disease
Centanni, Marco; N., Viceconti; S., Luisi; F. M., Reis; L., Gargano; F., Maiani; A., Franchi; Canettieri, Gianluca; F., Petraglia - 01a Articolo in rivista
paper: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (Springer Milano: Editrice Kurtis Srl) pp. 967-970 - issn: 0391-4097 - wos: WOS:000180443800009 (2) - scopus: 2-s2.0-0036964359 (2)

11573/143214 - 2001 - Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB
B. M., Mayr; Canettieri, Gianluca; M. R., Montminy - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 10936-10941 - issn: 0027-8424 - wos: WOS:000170966800078 (155) - scopus: 2-s2.0-0035845567 (155)

11573/495251 - 2001 - La desiodasi umana di tipo 2: dall’approccio molecolare alla fisiopatologia
Centanni, Marco; R., Sibilla; A., Franchi; S., Nardo; F., Maiani; Canettieri, Gianluca - 02a Capitolo o Articolo
book: Aggiornamento di Endocrinologia e Metabolismo. Dalla biologia molecolare alla clinica - ()

11573/363413 - 2000 - Isolation of human type 2 deiodinase gene promoter and characterization of a functional cyclic adenosine monophosphate response element
Canettieri, Gianluca; F. S., Celi; G., Baccheschi; L., Salvatori; Andreoli, Mario; Centanni, Marco - 01a Articolo in rivista
paper: ENDOCRINOLOGY (Endocrine Society / Maryland:8401 Connecticut Avenue, Suite 900:Chevy Chase, MD 20815:(301)941-0200, (301)941-0200, (301)941-0232, EMAIL: journals@endo-society.org, INTERNET: http://www.endo.society.org, Fax: (301)941-0259) pp. 1804-1813 - issn: 0013-7227 - wos: WOS:000088386000028 (51) - scopus: 2-s2.0-0034457460 (56)

11573/254804 - 2000 - Effect of tryptophan on the early tri-iodothyronine uptake in mouse thymocytes
Centanni, Marco; Canettieri, Gianluca; N., Viceconti; R., Sibilla; A., Bei; Andreoli, Mario - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF ENDOCRINOLOGY (Bristol: BioScientifica Oslo: Scandinavian University Press, 1994-) pp. 119-123 - issn: 0804-4643 - wos: WOS:000088162000016 (3) - scopus: 2-s2.0-0033940978 (3)

11573/248644 - 2000 - Structural organization and chromosomal localization of the human type II deiodinase gene
F. S., Celi; Canettieri, Gianluca; D., Mentuccia; L., Proietti Pannunzi; Fumarola, Angela; R., Sibilla; V., Predazzi; Ferraro, Marina; Andreoli, Mario; M., Ferraro; Centanni, Marco - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF ENDOCRINOLOGY (Bristol: BioScientifica Oslo: Scandinavian University Press, 1994-) pp. 267-271 - issn: 0804-4643 - wos: WOS:000088550100016 (17) - scopus: 2-s2.0-0033856519 (20)

11573/209361 - 1999 - Cloning and analysis of the mouse Insulin Receptor Substrate 3 gene Promoter.
Orecchio, A.; Giacchini, A.; Dominici, R.; Canettieri, G.; Trinti, B.; Zani, M.; Andreoli, Mario; Sciacchitano, Salvatore - 04a Atto di comunicazione a congresso
book: 28th National Congress of the Italian Society of Endocrinology (SIE) - ()

11573/209360 - 1999 - Cloning of the 5’ flanking region of the mouse Insulin Receptor Substrate – 3 gene.
Orecchio, A.; Giacchini, A.; Dominici, R.; Canettieri, G.; Trinti, B.; Zani, M.; Di Mario, Umberto; Andreoli, Mario; Sciacchitano, Salvatore - 04a Atto di comunicazione a congresso
book: 35th Annual Meeting of the European Association for the Study of Diabetes (EASD) - ()

11573/241965 - 1998 - Genomic characterization of the coding region of the human type II 5'-deiodinase gene
Celi, Fs; Canettieri, Gianluca; Yarnall, Dp; Burns, Dk; Andreoli, Mario; Shuldiner, Ar; Centanni, Marco - 01a Articolo in rivista
paper: MOLECULAR AND CELLULAR ENDOCRINOLOGY (Elsevier Science Ireland Limited:PO Box 85, Limerick Ireland:011 353 61 709600, 011 353 61 61944, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 353 61 709114) pp. 49-52 - issn: 0303-7207 - wos: WOS:000075235500008 (27) - scopus: 2-s2.0-0032566013 (36)

11573/242095 - 1998 - Combined impairment of nutritional parameters and thyroid homeostasis in mildly iodine-deficient children
Centanni, Marco; G., Majani; F., Vermiglio; Canettieri, Gianluca; G., Sanna; F., Moretti; F., Trimarchi; Andreoli, Mario - 01a Articolo in rivista
paper: THYROID (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 155-159 - issn: 1050-7256 - wos: WOS:000072273700007 (8) - scopus: 2-s2.0-0031940403 (9)

11573/243382 - 1997 - Reversible increase of intraocular pressure in young subclinical hypothyroid adults
Centanni, Marco; Cesareo, R; Verallo, O; Brinelli, M; Canettieri, Gianluca; Viceconti, N; Andreoli, Mario - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF ENDOCRINOLOGY (Bristol: BioScientifica Oslo: Scandinavian University Press, 1994-) pp. 595-598 - issn: 0804-4643 - wos: (0) - scopus: (0)

11573/143481 - 1996 - High plasma levels of endothelin-1 in untreated Addison's disease
Letizia, Claudio; Centanni, Marco; L., Scuro; Canettieri, Gianluca; S., Cerci; A., De Ciocchis; C., D'ambrosio; Scavo, Domenico - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF ENDOCRINOLOGY (Bristol: BioScientifica Oslo: Scandinavian University Press, 1994-) pp. 696-699 - issn: 0804-4643 - wos: WOS:A1996WE15100015 (5) - scopus: 2-s2.0-0030483610 (7)

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