GIAMPIERO BARDELLA

PhD Graduate

PhD program:: XXXIII


supervisor: Prof. Stefano Ferraina

Thesis title: Topology of local information dynamics during motor decision in the premotor cortex of primates.

Despite recent works have investigated functional and effective cortical networks in animal models, the dynamical information transfer underneath most of the higher brain functions is still unknown. Here we address the issue by analysing at the mesoscopic scale neuronal activities from a multielectrode array (96 channels) in the dorsal premotor cortex (PMd) of rhesus monkeys during a countermanding reaching task, requiring dynamical decisions after visual instructions. We used transfer entropy and graph theory to extract the PMd effective network and to quantify the local information patterns corresponding to motor decision-making. We found that the network of information processing is highly heterogeneous, information-spreader hubs exist and exhibit topological differences between movement generation and inhibition. Interestingly, within our framework we identified the presence of a hierarchical organization between four neuronal activity classes involved in the decision-making process. Moreover, we observed that the hierarchical organization changed when movement was executed or cancelled after programmed. We propose that motor decisions are based on the reorganization of local network formed by few subclasses of neuronal modules hierarchically organized

Research products

  • 11573/1679366 - 2023 - Reward prospect affects strategic adjustments in stop signal task (01a Articolo in rivista)
    GIUFFRIDA, VALENTINA; MARC, ISABEL BEATRICE; RAMAWAT, SURABHI; FONTANA, ROBERTO; FIORI, LORENZO; BARDELLA, GIAMPIERO; FAGIOLI, SABRINA; FERRAINA, STEFANO; BRUNAMONTI, EMILIANO; PANI, PIERPAOLO
  • 11573/1336004 - 2020 - The small scale functional topology of movement control: Hierarchical organization of local activity anticipates movement generation in the premotor cortex of primates (01a Articolo in rivista)
    BARDELLA, GIAMPIERO; PANI, PIERPAOLO; BRUNAMONTI, EMILIANO; GIARROCCO, FRANCO; FERRAINA, STEFANO
  • 11573/1470694 - 2021 - Neuronal dynamics of signal selective motor plan cancellation in the macaque dorsal premotor cortex (01a Articolo in rivista)
    GIARROCCO, FRANCO; BARDELLA, GIAMPIERO; GIAMUNDO, MARGHERITA; FABBRINI, FEDERICO; BRUNAMONTI, EMILIANO; PANI, PIERPAOLO; FERRAINA, STEFANO
  • 11573/1669953 - 2023 - Restart errors reaction time of a two-step inhibition process account for the violation of the race model’s independence in multi-effector selective stop signal task (01a Articolo in rivista)
    MARC, ISABEL BEATRICE; GIUFFRIDA, VALENTINA; RAMAWAT, SURABHI; FIORI, LORENZO; FONTANA, ROBERTO; BARDELLA, GIAMPIERO; FAGIOLI, SABRINA; FERRAINA, STEFANO; PANI, PIERPAOLO; BRUNAMONTI, EMILIANO
  • 11573/1682738 - 2023 - The premises of a transitive inference task modulate the synchrony of local field potentials in macaque dorsal premoto rcortex (04f Poster)
    MARC, ISABEL BEATRICE; BARDELLA, GIAMPIERO; GIUFFRIDA, VALENTINA; RAMAWAT, SURABHI; PANI, PIERPAOLO; FERRAINA, STEFANO; BRUNAMONTI, EMILIANO
  • 11573/1684222 - 2023 - Response inhibition in Premotor cortex corresponds to a complex reshuffle of the mesoscopic information network (01a Articolo in rivista)
    BARDELLA, GIAMPIERO; GIARROCCO, FRANCO; GIUFFRIDA, VALENTINA; BRUNAMONTI, EMILIANO; PANI, PIERPAOLO; FERRAINA, STEFANO
  • 11573/1681947 - 2023 - The transitive inference task to study the neuronal correlates of memory-driven decision making: a monkey neurophysiology perspective (01a Articolo in rivista)
    RAMAWAT, SURABHI; MARC, ISABEL BEATRICE; CECCARELLI, FRANCESCO; FERRUCCI, LORENZO; BARDELLA, GIAMPIERO; FERRAINA, STEFANO; PANI, PIERPAOLO; BRUNAMONTI, EMILIANO
  • 11573/1682600 - 2023 - Functional network complexity reflects diverse reward contexts in macaque premotor cortex (04f Poster)
    GIUFFRIDA, VALENTINA; BARDELLA, GIAMPIERO; RAMAWAT, SURABHI; MARC, ISABEL BEATRICE; FONTANA, ROBERTO; BRUNAMONTI, EMILIANO; PANI, PIERPAOLO; FERRAINA, STEFANO
  • 11573/1621694 - 2022 - Different Contribution of the Monkey Prefrontal and Premotor Dorsal Cortex in Decision Making During a Transitive Inference Task (01a Articolo in rivista)
    RAMAWAT, SURABHI; MIONE, VALENTINA; DI BELLO, FABIO; BARDELLA, GIAMPIERO; GENOVESIO, ALDO; PANI, PIERPAOLO; FERRAINA, STEFANO; BRUNAMONTI, EMILIANO
  • 11573/1646091 - 2022 - Reply to: Hannah et al. (2021) Commentary: ‘Does action-stopping involve separate pause and cancel processes? A view from premotor cortex’: Action-stopping models must consider the role of the dorsal premotor cortex (01b Commento, Erratum, Replica e simili)
    PANI, PIERPAOLO; GIARROCCO, FRANCO; BARDELLA, GIAMPIERO; BRUNAMONTI, EMILIANO; FERRAINA, STEFANO
  • 11573/1667801 - 2021 - Topology of local information dynamics during motor decision in the premotor cortex of primates (07a Tesi di Dottorato)
    BARDELLA, GIAMPIERO
  • 11573/1190409 - 2016 - Hierarchical organization of functional connectivity in the mouse brain: a complex network approach (01a Articolo in rivista)
    BARDELLA, GIAMPIERO

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