Phd in MORPHOGENESIS AND TISSUE ENGINEERING

email: gabriella.dobrowolny@uniroma1.it
phone: 0649766612
building: RM008
room: 32

Education and training
September 2018 National Academic Qualification as Associate Professor ASN BANDO D.D. 1532/2016 validity 24/9/2018-24/9/2027
June 2014 Specialist in Clinical Pathology Thesis title: “Serum microRNA as putative biomarkers for ALS disease
April 2004 PhD degree in Cell Science and Morphogenesis. Thesis title : “Enhanced expression of IGF1 attenuates muscle wasting in aging and Amyotrophic Lateral Sclerosis” DAHFMO-Unit of Histology and Medical Embryology Sapienza University of Rome
June 1999 Specialized School course in “Analytical references and Quality Control” at the University of Rome La Sapienza.
May 1998 Degree cum laude in Biology, at Sapienza University of Rome Thesis title: “Analysis of micronuclei and chromosoma malsegregation induced by vinblastin in human binucleated lymphocytes correlated with donors age”

Work experience
a.a, 2019/2020 - present teachers' board member of the PhD program in "Morphogenesis and Tissue Engineering"
June 2019- present RtdA BIO/17 at DAHFMO-Unit of Histology and Medical Embryology -Sapienza University of Rome
October 2013- August 2018 Specialist in Clinical Pathology and PhD scientist at IIT - Istituto Italiano di Tecnologia - in the field of Novel Nanotech-Based Approaches for the study and treatment of human diseases. She is currently coordinating a team working on the project .”Role of skeletal muscle in ALS disease pathogenesis”.
October 2008- October 2016 Lecturer of Histology in the “Anatomy Histology and Physiology” courses at Sapienza University of Rome and "Life Science" programs. Tutor of undergraduate students in Medicine, Biology and Medical Biotechnology.
April 2004 - October 2013 Research fellow
-for DAHFMO-Unit of Histology and Medical Embryology -Sapienza University of Rome,
-for Pasteur Institute- Cenci Bolognetti Fondation
-for the Association Française contre les Myopathies (AFM- France ) on the study of the molecular mechanism of the interplay between muscle and nerve in ALS disease
-for St.George’s University of London - Biomic Center- London UK.
During these periods she focused her study on the etiopathogenesis of neuromuscular disease.
October 2009- May 2014 Trainee in Clinical Pathology specialization program
May 2000-April 2004 PhD student in Cell Science and Morphogenesis program and Academic visitors at St.George’s University of London - Biomic Center- London UK
October 1999-April 2000 Clinical monitor for Merck Sharp & Dohme in charge of two phase IV clinical trials.
June 1998 - October 1999 Research Fellow for Istituto Superiore di Sanità.

Teaching experience
2008/09 to 2011/12 Lecture in Histology in the Anatomy Histology Physiology course of Nursery school degree-CdlB-Sapienza University of Rome
2019/2020 Lecture in Histology in the "Morphological and functional bases of human body” course and Genetics in "Cellular and molecular bases of life" course of Medical radiology imaging techniques and radiotherapy school degree - Policlinico Umberto I- Sapienza University of Rome-
2020/2021- today Lecture in Histology and Embryology in Medicine and Surgery HT school degree-Sapienza University; today Lecture in Histology and Embryology in Medicine and Surgery school degree-CdL B -Sapienza University

Scientific research activities
The scientific work lead to the publication of 41 papers, some of which has been published in high scientific impact journal such as Nat. Gen. (2001), PNAS (2004), JCB (2005) Cell Metab. (2008), ARS (2018), Sci. Rep. (2019)

Grants and awards
PI for Association Française contre les Myopathies (AFM) 2023 Deconvoluting human ALS muscle environment by Spatial Transcriptomics
Component in PNRR grant-Centro Nazionale 5 - Spoke 7
Component in PNRR grant-Centro Nazionale 3 - Spoke 9
Component Bando di Ateneo Progetti Dipartimentali 2023 The tumor microenvironoment; from cellular mechanism to personalized treatment
PI Bando di Ateneo 2019 Sapienza university of Rome n. RM120172A9047D57- "Circadian restoration of metabolic homeostasis as a novel strategy to counteract ALS disease".Bando di Ateneo 2019 Sapienza university of Rome n. RM120172A9047D57- "Circadian restoration of metabolic homeostasis as a novel strategy to counteract ALS disease".
The scientific research study “Skeletal muscle is a primary target of SOD1G93A- mediated toxicity” has been awarded as “Research of excellence” during “Sapienza e Ricerca” event, 2009 edition. Macro-area 6.
Holder of the Interuniversity Institute of Myology (IIM) Research Grant for the project “Characterization of the molecular trigger of muscle atrophy and denervartion in a novel ALS mouse model”