FRANCESCO SPALLOTTA

Ricercatore universitario

email: francesco.spallotta@uniroma1.it


stanza: 14

TITOLI DI STUDIO:
02/2011: Dottorato in Medicina Sperimentale - Sapienza Università di Roma
12/2006: Laurea con lode in Biotecnologie Mediche, Molecolari e Cellulari - Sapienza Università di Roma
10/2004: Laurea con lode in Biotecnologie - Sapienza Università di Roma

ATTIVITA PROFESSIONALE:
09/2022-presente: Ricercatore Tempo Determinato tipo B (RTD-B) SSD MED/04-Patologia generale, Sapienza Università di Roma (Italia)
11/2019-08/2022: Ricercatore III livello presso il laboratorio di Fisiopatologia Integrata dell'Istituto di analisi dei sistemi ed informatica "Antonio Ruberti" Consiglio Nazionale delle Ricerche (IASI CNR), Roma (Italia)
07/2018-02/2020: Assegnista presso il laboratorio di Epigenetica del Cancro dell Istituto Tumori Candiolo, IRCCS - Dip. Di Oncologia dell Università di Torino (Italia)
08/2012-06/2018: Ricercatore postdoc presso la Divisione di Epigenetica Cardiovascolare, Università Goethe di Francoforte sul Meno (Germania)
02/2010-06/2012: Ricercatore postdoc/dottorando presso il laboratorio di Biologia Vascolare e Medicina Rigenerativa del Centro Cardiologico Monzino, IRCCS Milano (Italia)
01/2007-01/2010: Contrattista presso il laboratorio di Patologia Vascolare dell Istituto Dermopatico dell Immacolata (IDI), IRCCS Roma (Italia)

PREMI:
11/2016: FTGB Young Investigator Award - Council on Functional Genomics and Translational Biology, American Heart Scientific Session 2016 New Orleans, USA.

FINANZIAMENTI:
2022: Responsabile del Progetto Bando SEED 2022 Sapienza Università di Roma. Titolo progetto: The hyperglycaemic memory impact on the epi-metabolic landscape of pancreatic tumor stroma
2020-2025: Responsabile del Progetto My First AIRC (MFAG), Fondazione AIRC per la Ricerca sul Cancro (AIRC). Titolo progetto: Metabolic regulation of the DNA demethylation enzymatic machinery in pancreatic cancer .
2020-2021: Co-responsabile del Progetto finanziato da Karolinska Institutet Research Foundation (Grants 2020-2021), Sweden. Project title: "Targeting metabomiR-144 to prevent the development of hepatocellular carcinoma in patients with non-alcoholic steatohepatitis"
2016-2017: Co-responsabile del Progetto finanziato da Kerckhoff Klinik, Bad Nauheim, Germany. Titolo progetto: Analysis of epi-metabolic effect of statins and type II diabetes on cardiac fibroblasts and lymphocytes in patients with coronary heart disease (CHD) and the indication of coronary artery bypass operation (ACB)
2015-2016: Responsabile del Progetto Start-up grant from the DFG (German Research Foundation), Excellence Cluster Cardio Pulmonary System (ECCPS) , Germany. Titolo progetto: Epimetabolic Assessment of Human Cardiac Stromal Cells as Sensors of the Heart micro-environment
2015: Responsabile del Progetto Start-up grant from the LOEWE Center for Gene Therapy (LOEWE-CGT) - Frankfurt am Main, Germany. Titolo progetto: Identification of zinc-finger protein Castor 1 (Casz1) targets important during cardiac mesenchymal stromal cell reprogramming into cardiomyocyte precursors
2012-2013: Responsabile del Progetto Start-up grant from the LOEWE Center for Gene Therapy (LOEWE-CGT) - Frankfurt am Main, Germany. Titolo progetto: Identification of functional long non coding RNAs crucial for human stromal cell reprogramming to vascular and cardiac precursors in response to nitric oxide

APPARTENENZA SOCIETA SCIENTIFICHE (presente/passato):
- American Heart Association (AHA)
- European Association for the Study of Diabetes (EFSD)
- American Association for Cancer Research (AACR)
- European Association for Cancer Research (EACR)

INFORMAZIONI BIBLOGRAFICHE:
Numero di articoli/review/editoriali pubblicate su giornali internazionali peer-reviewed: 44 (Scopus)
Number of citations: 1462 (Scopus)
h-index: 23 (Scopus)
Scopus ID: 35604948700
ORCID: https://orcid.org/0000-0002-0466-6286

Membro dell Editorial Board della rivista Nutrients. Svolge attività di Ad Hoc di Reviewer per varie riviste internazionali tra cui Metabolites, Theranostics, eBiomedicine, Cell Death and Differentation, European Journal of Pharmacology, Scientific Reports, Cancers, Arteriosclerosis, Thrombosis, and Vascular Biology.

Produzione scientifica

11573/1707348 - 2024 - Targeting staphylococcal enterotoxin B binding to CD28 as a new strategy for dampening superantigen-mediated intestinal epithelial barrier dysfunctions
Amormino, C.; Russo, E.; Tedeschi, V.; Fiorillo, M. T.; Paiardini, A.; Spallotta, F.; Rosano, L.; Tuosto, L.; Kunkl, M. - 01a Articolo in rivista
rivista: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-3224 - wos: WOS:001187533300001 (0) - scopus: 2-s2.0-85188131451 (0)

11573/1723579 - 2024 - Crosstalk and communication of cancer-associated fibroblasts with natural killer and dendritic cells: New frontiers and unveiled opportunities for cancer immunotherapy
Ielpo, S; Barberini, F; Dabbagh Moghaddam, F; Pesce, S; Cencioni, C; Spallotta, F; De Ninno, A; Businaro, L; Marcenaro, E; Bei, R; Cifaldi, L; Barillari, G; Melaiu, O - 01g Articolo di rassegna (Review)
rivista: CANCER TREATMENT REVIEWS (-Attuale:W B SAUNDERS CO LTD, 32 JAMESTOWN RD, LONDON, ENGLAND, NW1 7BY -Harcourt Publishers Limited:Foots Cray High Street, Sidcup Kent DA14 5HP United Kingdom:011 44 20 83085700, EMAIL: journals@harcourt.com, INTERNET: http://www.harcourt-international.com, Fax: 011 44 20 83085876) pp. - - issn: 0305-7372 - wos: WOS:001344303800001 (0) - scopus: 2-s2.0-85206912446 (0)

11573/1721298 - 2024 - Inactivation of HIPK2 attenuates KRASG12D activity and prevents pancreatic tumorigenesis
Sozzi, Silvia; Manni, Isabella; Ercolani, Cristiana; Grazia Diodoro, Maria; Bartolazzi, Armando; Spallotta, Francesco; Piaggio, Giulia; Monteonofrio, Laura; Soddu, Silvia; Rinaldo &Amp;, Cinzia; Valente, Davide - 01a Articolo in rivista
rivista: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. - - issn: 1756-9966 - wos: WOS:001325036800002 (0) - scopus: 2-s2.0-85205336703 (0)

11573/1721296 - 2024 - High fat diet affects the hippocampal expression of miRNAs targeting brain plasticity-related genes
Spinelli, M; Spallotta, F; Cencioni, C; Natale, F; Re, A; Dellaria, A; Farsetti, A; Fusco, S; Grassi, C. - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:001297470500002 (0) - scopus: 2-s2.0-85201980120 (0)

11573/1672951 - 2023 - The "Superoncogene" Myc at the crossroad between metabolism and gene expression in glioblastoma multiforme
Cencioni, Chiara; Scagnoli, Fiorella; Spallotta, Francesco; Nasi, Sergio; Illi, Barbara - 01g Articolo di rassegna (Review)
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000939026300001 (4) - scopus: 2-s2.0-85148946033 (4)

11573/1681026 - 2023 - Bivalent binding of staphylococcal superantigens to the TCR and CD28 triggers inflammatory signals independently of antigen presenting cells
Kunkl, Martina; Amormino, Carola; Spallotta, Francesco; Caristi, Silvana; Fiorillo, Maria Teresa; Paiardini, Alessandro; Kaempfer, Raymond; Tuosto, Loretta - 01a Articolo in rivista
rivista: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-3224 - wos: WOS:000988435800001 (4) - scopus: 2-s2.0-85159695596 (3)

11573/1658229 - 2022 - Gastrointestinal Cancer Patient Nutritional Management: From Specific Needs to Novel Epigenetic Dietary Approaches
Cencioni, Chiara; Trestini, Ilaria; Piro, Geny; Bria, Emilio; Tortora, Giampaolo; Carbone, Carmine; Spallotta, Francesco - 01g Articolo di rassegna (Review)
rivista: NUTRIENTS (Basel, Switzerland: Molecular Diversity Preservation International (MDPI)) pp. - - issn: 2072-6643 - wos: WOS:000786154100001 (9) - scopus: 2-s2.0-85127911347 (10)

11573/1658851 - 2022 - MALAT1 as a regulator of the androgen-dependent choline kinase a gene in the metabolic rewiring of prostate cancer
De Martino, Sara; Iorio, Egidio; Cencioni, Chiara; Aiello, Aurora; Spallotta, Francesco; Chirico, Mattea; Pisanu, Maria Elena; Grassi, Claudio; Pontecorvi, Alfredo; Gaetano, Carlo; Nanni, Simona; Farsetti, Antonella - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000819642200001 (3) - scopus: 2-s2.0-85131674512 (3)

11573/1661079 - 2022 - SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
Hammer, Q; Dunst, J; Christ, W; Picarazzi, F; Wendorff, M; Momayyezi, P; Huhn, O; Netskar, Hk; Maleki, Kt; García, M; Sekine, T; Sohlberg, E; Azzimato, V; Aouadi, M; Karolinska Covid-19 Study, Group; Severe Covid-19 Gwas, Group; Degenhardt, F; Franke, A; Spallotta, F; Mori, M; Michaëlsson, J; Björkström, Nk; Rückert, T; Romagnani, C; Horowitz, A; Klingström, J; Ljunggren, Hg; Malmberg, Kj. - 01a Articolo in rivista
rivista: CELL REPORTS (Elsevier B.V. Cambridge MA: Cell Press) pp. - - issn: 2211-1247 - wos: WOS:000768326700001 (29) - scopus: 2-s2.0-85125530610 (36)

11573/1661078 - 2021 - Hepatic miR-144 drives fumarase activity preventing NRF2 activation during obesity
Azzimato, V; Chen, P; Barreby, E; Morgantini, C; Levi, L; Vankova, A; Jager, J; Sulen, A; Diotallevi, M; Shen, Jx; Miller, A; Ellis, E; Rydén, M; Näslund, E; Thorell, A; Lauschke, Vm; Channon, Km; Crabtree, Mj; Haschemi, A; Craige, Sm; Mori, M; Spallotta, F; Aouadi, M. - 01a Articolo in rivista
rivista: GASTROENTEROLOGY (USA: Elsevier Philadelphia, PA: W B Saunders Company) pp. 1982-1997 - issn: 0016-5085 - wos: WOS:000720747800003 (37) - scopus: 2-s2.0-85117193472 (38)

11573/1664440 - 2021 - Intratumoral injection of TLR9 agonist promotes an immunopermissive microenvironment transition and causes cooperative antitumor activity in combination with anti-PD1 in pancreatic cancer
Carbone, Carmine; Piro, Geny; Agostini, Antonio; Delfino, Pietro; De Sanctis, Francesco; Nasca, Vincenzo; Spallotta, Francesco; Sette, Claudio; Martini, Maurizio; Ugel, Stefano; Corbo, Vincenzo; Cappello, Paola; Bria, Emilio; Scarpa, Aldo; Tortora, Giampaolo - 01a Articolo in rivista
rivista: JOURNAL FOR IMMUNOTHERAPY OF CANCER ([London] : BioMed Central) pp. - - issn: 2051-1426 - wos: WOS:000754860300010 (31) - scopus: 2-s2.0-85114613348 (32)

11573/1654873 - 2021 - Pillars and Gaps of S-Nitrosylation-Dependent Epigenetic Regulation in Physiology and Cancer
Salvatori, Luisa; Spallotta, Francesco; Gaetano, Carlo; Illi, Barbara - 01g Articolo di rassegna (Review)
rivista: LIFE (Basel: MDPI) pp. - - issn: 2075-1729 - wos: WOS:000745264100001 (5) - scopus: 2-s2.0-85122374806 (5)

11573/1678741 - 2019 - Fibroblasts in Nodular Sclerosing Classical Hodgkin Lymphoma Are Defined by a Specific Phenotype and Protect Tumor Cells from Brentuximab-Vedotin Induced Injury
Bankov, Katrin; Döring, Claudia; Ustaszewski, Adam; Giefing, Maciej; Herling, Marco; Cencioni, Chiara; Spallotta, Francesco; Gaetano, Carlo; Küppers, Ralf; Hansmann, Martin-Leo; Hartmann, Sylvia - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000502290100069 (12) - scopus: 2-s2.0-85074500393 (12)

11573/1678743 - 2019 - Dissecting cytosine methylation mechanics of dysmetabolism
Cencioni, Chiara; Gaetano, Carlo; Spallotta, Francesco - 01m Editorial/Introduzione in rivista
rivista: AGING (Impact Journals LLC) pp. 837-838 - issn: 1945-4589 - wos: WOS:000459482200001 (1) - scopus: 2-s2.0-85061617596 (0)

11573/1678742 - 2019 - Aging Triggers H3K27 Trimethylation Hoarding in the Chromatin of Nothobranchius furzeri Skeletal Muscle
Cencioni, Chiara; Heid, Johanna; Krepelova, Anna; Mohammad Mahdi Rasa, Seyed; Kuenne, Carsten; Guenther, Stefan; Baumgart, Mario; Cellerino, Alessandro; Neri, Francesco; Spallotta, Francesco; Gaetano, Carlo - 01a Articolo in rivista
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000497336400058 (13) - scopus: 2-s2.0-85086524429 (13)

11573/1255617 - 2019 - P300/CBP-associated factor regulates transcription and function of isocitrate dehydrogenase 2 during muscle differentiation
Savoia, Matteo; Cencioni, Chiara; Mori, Mattia; Atlante, Sandra; Zaccagnini, Germana; Devanna, Paolo; Di Marcotullio, Lucia; Botta, Bruno; Martelli, Fabio; Zeiher, Andreas M; Pontecorvi, Alfredo; Farsetti, Antonella; Spallotta, Francesco; Gaetano, Carlo - 01a Articolo in rivista
rivista: THE FASEB JOURNAL (Federation of American Societies for Experimental Biology (FASEB):9650 Rockville Pike, Room L-2310:Bethesda, MD 20814:(800)433-2732, (301)530-7027, EMAIL: staff@dues.faseb.org, INTERNET: http://www.faseb.org, Fax: (301)571-5728, (301)530-7001) pp. 4107-4123 - issn: 0892-6638 - wos: WOS:000459794800081 (10) - scopus: 2-s2.0-85063423944 (9)

11573/1679227 - 2018 - Structural and biological characterization of new hybrid drugs joining an HDAC inhibitor to different NO-donors
Atlante, Sandra; Chegaev, Konstantin; Cencioni, Chiara; Guglielmo, Stefano; Marini, Elisabetta; Borretto, Emily; Gaetano, Carlo; Fruttero, Roberta; Spallotta, Francesco; Lazzarato, Loretta - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ([Paris] : Elsevier, [198?]-) pp. 612-625 - issn: 1768-3254 - wos: WOS:000425198100045 (17) - scopus: 2-s2.0-85039425327 (18)

11573/1678746 - 2018 - α-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis
Atlante, Sandra; Visintin, Alessia; Marini, Elisabetta; Savoia, Matteo; Dianzani, Chiara; Giorgis, Marta; Sürün, Duran; Maione, Federica; Schnütgen, Frank; Farsetti, Antonella; Zeiher, Andreas M.; Bertinaria, Massimo; Giraudo, Enrico; Spallotta, Francesco; Cencioni, Chiara; Gaetano, Carlo - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. 756- - issn: 2041-4889 - wos: WOS:000438367000004 (52) - scopus: 2-s2.0-85049739922 (54)

11573/1672864 - 2018 - Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells
Cencioni, Chiara; Spallotta, Francesco; Savoia, Matteo; Kuenne, Carsten; Guenther, Stefan; Re, Agnese; Wingert, Susanne; Rehage, Maike; Sürün, Duran; Siragusa, Mauro; G Smith, Jacob; Schnütgen, Frank; Von Melchner, Harald; A Rieger, Michael; Martelli, Fabio; Riccio, Antonella; Fleming, Ingrid; Braun, Thomas; M Zeiher, Andreas; Farsetti, Antonella; Gaetano, Carlo - 01a Articolo in rivista
rivista: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. - - issn: 2041-1723 - wos: WOS:000428621300005 (14) - scopus: 2-s2.0-85044611477 (14)

11573/1678745 - 2018 - A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets
F Almeida, Francisca; Tognarelli, Sara; Marçais, Antoine; J Kueh, Andrew; E Friede, Miriam; Liao, Yang; N Willis, Simon; Luong, Kylie; Faure, Fabrice; E Mercier, Francois; Galluso, Justine; Firth, Matthew; Narni-Mancinelli, Emilie; Rais, Bushra; T Scadden, David; Spallotta, Francesco; Weil, Sandra; Giannattasio, Ariane; Kalensee, Franziska; Zöller, Tobias; D Huntington, Nicholas; Schleicher, Ulrike; G Chiocchetti, Andreas; Ugolini, Sophie; J Herold, Marco; Shi, Wei; Koch, Joachim; Steinle, Alexander; Vivier, Eric; Walzer, Thierry; T Belz, Gabrielle; Ullrich, Evelyn - 01a Articolo in rivista
rivista: ONCOIMMUNOLOGY ([Abingdon]: Taylor & Francis) pp. - - issn: 2162-402X - wos: WOS:000446116700003 (10) - scopus: 2-s2.0-85052105419 (11)

11573/1072717 - 2018 - Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: Rescue by α-ketoglutarate and TET-TDG functional reactivation
Spallotta, Francesco; Cencioni, Chiara; Atlante, Sandra; Garella, Davide; Cocco, Mattia; Mori, Mattia; Mastrocola, Raffaella; Kuenne, Carsten; Guenther, Stefan; Nanni, Simona; Azzimato, Valerio; Zukunft, Sven; Kornberger, Angela; Sürün, Duran; Schnütgen, Frank; Von Melchner, Harald; Di Stilo, Antonella; Aragno, Manuela; Braspenning, Maarten; Van Criekinge, Wim; De Blasio, Miles J.; Ritchie, Rebecca H.; Zaccagnini, Germana; Martelli, Fabio; Farsetti, Antonella; Fleming, Ingrid; Braun, Thomas; Beiras-Fernandez, Andres; Botta, Bruno; Collino, Massimo; Bertinaria, Massimo; Zeiher, Andreas M.; Gaetano, Carlo - 01a Articolo in rivista
rivista: CIRCULATION RESEARCH (Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320 PRimo editore: Baltimore, Md. : Grune & Stratton, c1953-) pp. 31-46 - issn: 0009-7330 - wos: WOS:000419347100013 (32) - scopus: 2-s2.0-85040168895 (39)

11573/1679228 - 2017 - The double life of cardiac mesenchymal cells: epimetabolic sensors and therapeutic assets for heart regeneration
Cencioni, Chiara; Atlante, Sandra; Savoia, Matteo; Martelli, Fabio; Farsetti, Antonella; C Capogrossi, Maurizio; M Zeiher, Andreas; Gaetano, Carlo; Spallotta, Francesco - 01g Articolo di rassegna (Review)
rivista: PHARMACOLOGY & THERAPEUTICS (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 43-55 - issn: 0163-7258 - wos: WOS:000396949200004 (12) - scopus: 2-s2.0-85008931464 (14)

11573/1679714 - 2017 - Deciphering histone code enigmas sheds new light on cardiac regeneration
Cencioni, Chiara; Spallotta, Francesco; Farsetti, Antonella; M Zeiher, Andreas; Gaetano, Carlo - 01m Editorial/Introduzione in rivista
rivista: CIRCULATION RESEARCH (Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320 PRimo editore: Baltimore, Md. : Grune & Stratton, c1953-) pp. 1370-1372 - issn: 0009-7330 - wos: WOS:000400396500001 (0) - scopus: 2-s2.0-85019599070 (0)

11573/1679715 - 2017 - Dark side of the deep heart
Cencioni, Chiara; Spallotta, Francesco; Gaetano, Carlo - 01m Editorial/Introduzione in rivista
rivista: CIRCULATION, CARDIOVASCULAR GENETICS (Philadelphia, PA : Lippincott Williams & Wilkins) pp. - - issn: 1942-325X - wos: WOS:000403432900024 (0) - scopus: 2-s2.0-85021155883 (0)

11573/1679222 - 2017 - Age-dependent increase of oxidative stress regulates microRNA-29 family preserving cardiac health
Heid, Johanna; Cencioni, Chiara; Ripa, Roberto; Baumgart, Mario; Atlante, Sandra; Milano, Giuseppina; Scopece, Alessandro; Kuenne, Carsten; Guenther, Stefan; Azzimato, Valerio; Farsetti, Antonella; Rossi, Giacomo; Braun, Thomas; Pompilio, Giulio; Martelli, Fabio; M Zeiher, Andreas; Cellerino, Alessandro; Gaetano, Carlo; Spallotta, Francesco - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000417025400020 (49) - scopus: 2-s2.0-85037176531 (52)

11573/1680074 - 2016 - Design and synthesis of N-benzoyl amino acid derivatives as DNA methylation inhibitors
Garella, Davide; Atlante, Sandra; Borretto, Emily; Cocco, Mattia; Giorgis, Marta; Costale, Annalisa; Stevanato, Livio; Miglio, Gianluca; Cencioni, Chiara; Fernández-De Gortari, Eli; L Medina-Franco, José; Spallotta, Francesco; Gaetano, Carlo; Bertinaria, Massimo - 01a Articolo in rivista
rivista: CHEMICAL BIOLOGY & DRUG DESIGN ([Oxford] : Blackwell) pp. 664-676 - issn: 1747-0285 - wos: WOS:000386065500003 (11) - scopus: 2-s2.0-84990181134 (13)

11573/1680073 - 2016 - Anacardic acid and thyroid hormone enhance cardiomyocytes production from undifferentiated mouse ES cells along functionally distinct pathways
Re, Agnese; Nanni, Simona; Aiello, Aurora; Granata, Serena; Colussi, Claudia; Campostrini, Giulia; Spallotta, Francesco; Mattiussi, Stefania; Pantisano, Valentina; D'angelo, Carmen; Biroccio, Annamaria; Rossini, Alessandra; Barbuti, Andrea; Difrancesco, Dario; Trimarchi, Francesco; Pontecorvi, Alfredo; Gaetano, Carlo; Farsetti, Antonella - 01a Articolo in rivista
rivista: ENDOCRINE (New York, Berlin: Springer Totowa, N.J. : Humana Press) pp. -681 - issn: 1559-0100 - wos: WOS:000383022600010 (5) - scopus: 2-s2.0-84946763297 (7)

11573/870523 - 2016 - 1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells
Valente, Sergio; Mellini, Paolo; Spallotta, Francesco; Carafa, Vincenzo; Nebbioso, Angela; Polletta, Lucia; Carnevale, Ilaria; Saladini, Serena; Trisciuoglio, Daniela; Gabellini, Chiara; Tardugno, Maria; Zwergel, Clemens; Cencioni, Chiara; Atlante, Sandra; Moniot, Sébastien; Steegborn, Clemens; Budriesi, Roberta; Tafani, Marco; Del Bufalo, Donatella; Altucci, Lucia; Gaetano, Carlo; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1471-1491 - issn: 0022-2623 - wos: WOS:000371103600016 (57) - scopus: 2-s2.0-84959335947 (62)

11573/884213 - 2015 - Sirtuin function in aging heart and vessels
Cencioni, Chiara; Spallotta, Francesco; Mai, Antonello; Martelli, Fabio; Farsetti, Antonella; Zeiher, Andreas M.; Gaetano, Carlo - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 55-61 - issn: 0022-2828 - wos: WOS:000356839100007 (74) - scopus: 2-s2.0-84937970546 (80)

11573/1679224 - 2014 - RNA-seq of the aging brain in the short-lived fish N. furzeri - conserved pathways and novel genes associated with neurogenesis
Baumgart, Mario; Groth, Marco; Priebe, Steffen; Savino, Aurora; Testa, Giovanna; Dix, Andreas; Ripa, Roberto; Spallotta, Francesco; Gaetano, Carlo; Ori, Michela; Terzibasi Tozzini, Eva; Guthke, Reinhard; Platzer, Matthias; Cellerino, Alessandro - 01a Articolo in rivista
rivista: AGING CELL ([Oxford] : Blackwell Science Ltd, 2002-) pp. 965-974 - issn: 1474-9726 - wos: (0) - scopus: 2-s2.0-84911989557 (114)

11573/1680078 - 2014 - Epigenetic mechanisms of hyperglycemic memory
Cencioni, Chiara; Spallotta, Francesco; Greco, Simona; Martelli, Fabio; M Zeiher, Andreas; Gaetano, Carlo - 01g Articolo di rassegna (Review)
rivista: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 155-158 - issn: 1357-2725 - wos: (0) - scopus: 2-s2.0-84899885205 (43)

11573/1679225 - 2014 - Essential role of the zinc finger transcription factor Casz1 for mammalian cardiac morphogenesis and development
Liu, Zhihui; Li, Wenling; Ma, Xuefei; Ding, Nancy; Spallotta, Francesco; Southon, Eileen; Tessarollo, Lino; Gaetano, Carlo; Mukouyama, Yoh-Suke; J Thiele, Carol - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 29801-29816 - issn: 0021-9258 - wos: (0) - scopus: 2-s2.0-84908180993 (57)

11573/884231 - 2014 - The histone acetylase activator pentadecylidenemalonate 1b rescues proliferation and differentiation in the human cardiac mesenchymal cells of type 2 diabetic patients
Vecellio, Matteo; Spallotta, Francesco; Nanni, Simona; Colussi, Claudia; Cencioni, Chiara; Derlet, Anja; Bassetti, Beatrice; Tilenni, Manuela; Carena, Maria Cristina; Farsetti, Antonella; Sbardella, Gianluca; Castellano, Sabrina; Mai, Antonello; Martelli, Fabio; Pompilio, Giulio; Capogrossi, Maurizio C.; Rossini, Alessandra; Dimmeler, Stefanie; Zeiher, Andreas; Gaetano, Carlo - 01a Articolo in rivista
rivista: DIABETES (American Diabetes Association:National Service Center, 1701 North Beaureguard Street:Alexandria, VA 22311:(800)232-3472, (703)549-1500, INTERNET: http://www.diabetes.org/diabetscare, Fax: (703)549-6995) pp. 2132-2147 - issn: 0012-1797 - wos: WOS:000336643900037 (59) - scopus: 2-s2.0-84899824083 (62)

11573/513469 - 2013 - A Nitric Oxide-dependent crosstalk between class I and III Histone Deacetylases accelerates skin repair.
2. Spallotta, F.; Cencioni, C.; Straino, S.; Nanni, S.; Rosati, J.; Artuso, S.; Manni, I.; Colussi, C.; Piaggio, G.; Martelli, F.; Valente, Sergio; Mai, Antonello; Capogrossi, M. C.; Farsetti, A.; Gaetano, C. - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 11004-11012 - issn: 0021-9258 - wos: WOS:000317915500007 (66) - scopus: 2-s2.0-84876580701 (71)

11573/1680080 - 2013 - Synthesis and biological evaluation of the first example of NO-donor histone deacetylase inhibitor
Borretto, Emily; Lazzarato, Loretta; Spallotta, Francesco; Cencioni, Chiara; D'alessandra, Yuri; Gaetano, Carlo; Fruttero, Roberta; Gasco, Alberto - 01a Articolo in rivista
rivista: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 994-999 - issn: 1948-5875 - wos: (0) - scopus: 2-s2.0-84885455091 (47)

11573/525990 - 2013 - Oxidative stress and epigenetic regulation in ageing and age-related diseases
Chiara, Cencioni; Spallotta, Francesco; Fabio, Martelli; Valente, Sergio; Mai, Antonello; Zeiher Am, Gaetano C. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 17643-17663 - issn: 1661-6596 - wos: WOS:000328623900021 (151) - scopus: 2-s2.0-84883479431 (176)

11573/525042 - 2013 - Detrimental effect of class-selective histone deacetylase inhibitors during tissue regeneration following hindlimb ischemia
Spallotta, F.; Silvia, Tardivo; Nanni, S.; Rosati, J. D.; Straino, S.; Mai, Antonello; Vecellio, M.; Valente, Sergio; Capogrossi, M. C.; Farsetti, A.; Martone, Julie; Bozzoni, Irene; Pontecorvi, A.; Gaetano, C.; Colussi, C. - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 22915-22929 - issn: 0021-9258 - wos: WOS:000330598200004 (27) - scopus: 2-s2.0-84881396773 (25)

11573/485037 - 2012 - P300/CBP associated factor regulates nitroglycerin-dependent arterial relaxation by nε-lysine acetylation of contractile proteins
Colussi, C.; Scopece, A.; Vitale, S.; Spallotta, F.; Mattiussi, S.; Rosati, J.; Illi, B.; Mai, Antonello; Castellano, S.; Sbardella, Gianluca; Farsetti, A.; C, Gaetano; Mc, Capogrossi - 01a Articolo in rivista
rivista: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY (-PHILADELPHIA, USA: LIPPINCOTT WILLIAMS & WILKINS -Dallas, TX : The Association, c1995-) pp. 2435-2443 - issn: 1079-5642 - wos: WOS:000308811200013 (28) - scopus: 2-s2.0-84866630451 (27)

11573/380081 - 2011 - Nε-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart
Colussi, C; Rosati, J; Straino, S; Spallotta, F; Berni, R; Stilli, D; Rossi, S; Musso, E; Macchi, E; Mai, Antonello; Sbardella, G; Castellano, S; Chimenti, Cristina; Frustaci, Andrea; Nebbioso, A; Altucci, L; Capogrossi, Mc; Gaetano, C. - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (Editore National Academy of Sciences a Washington, DC) pp. 2795-2800 - issn: 1091-6490 - wos: WOS:000287377000035 (88) - scopus: 2-s2.0-79952613152 (89)

11573/1680069 - 2011 - NO points to epigenetics in vascular development
Illi, Barbara; Colussi, Claudia; Rosati, Jessica; Spallotta, Francesco; Nanni, Simona; Farsetti, Antonella; C Capogrossi, Maurizio; Gaetano, Carlo - 01g Articolo di rassegna (Review)
rivista: CARDIOVASCULAR RESEARCH (editore attuale: ELSEVIER SCIENCE BV, PO BOX 211, AMSTERDAM, NETHERLANDS, 1000 AE primo editore: BMJ / British Medical Journal Publishing Group:PO Box 299, London WC1H 9TD United Kingdom:011 44 20 73836270, EMAIL: subscriptions@bmjgroup.com, INTERNET: http://www.bmjpg.com/bmj, Fax: 011 44 20 73836402) pp. 447-456 - issn: 0008-6363 - wos: (0) - scopus: 2-s2.0-79957474768 (12)

11573/379809 - 2011 - Smad-interacting protein-1 and microRNA 200 family define a nitric oxide-dependent molecular circuitry involved in embryonic stem cell mesendoderm differentiation
Rosati, J.; Spallotta, F.; Nanni, S.; Grasselli, A.; Antonini, A.; Vincenti, S.; Presutti, Carlo; Colussi, C.; D'angelo, C.; Biroccio, A.; Farsetti, A.; Capogrossi, M. C.; Illi, B.; Gaetano, C. - 01a Articolo in rivista
rivista: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY (-PHILADELPHIA, USA: LIPPINCOTT WILLIAMS & WILKINS -Dallas, TX : The Association, c1995-) pp. 898-907 - issn: 1079-5642 - wos: WOS:000288437800028 (23) - scopus: 2-s2.0-79953744099 (27)

11573/13665 - 2010 - Histone deacetylase inhibitors: Keeping momentum for neuromuscular and cardiovascular diseases treatment
Claudia, Colussi; Barbara, Illi; Jessica, Rosati; Spallotta, Francesco; Antonella, Farsetti; Annalisa, Grasselli; Mai, Antonello; Capogrossi Mc, Gaetano C. - 01g Articolo di rassegna (Review)
rivista: PHARMACOLOGICAL RESEARCH (Attuale:ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 24-28 OVAL RD, LONDON, ENGLAND, NW1 7DX Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 3-10 - issn: 1043-6618 - wos: WOS:000278613800002 (39) - scopus: 2-s2.0-77952880971 (41)

11573/13728 - 2010 - Proteomic profile of differentially expressed plasma proteins from dystrophic mice and following suberoylanilide hydroxamic acid treatment
Colussi, C.; Banfi, C.; Brioschi, M.; Tremoli, E.; Straino, S.; Spallotta, F.; Mai, Antonello; Rotili, Dante; Capogrossi Mc, Gaetano C. - 01a Articolo in rivista
rivista: PROTEOMICS. CLINICAL APPLICATIONS (Weinheim : Wiley-VCH-Verl.) pp. 71-83 - issn: 1862-8346 - wos: WOS:000274264900007 (30) - scopus: 2-s2.0-77951727320 (31)

11573/13666 - 2010 - The histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces cardiac arrhythmias in dystrophic mice
Colussi, C.; Berni, R.; Rosati, J.; Straino, S.; Vitale, S.; Spallotta, F.; Baruffi, S.; Bocchi, L.; Delucchi, F.; Rossi, S.; Savi, M.; Rotili, Dante; Quaini, F.; Macchi, E.; Stilli, D.; Musso, E.; Mai, Antonello; Capogrossi Mc, Gaetano C. - 01a Articolo in rivista
rivista: CARDIOVASCULAR RESEARCH (editore attuale: ELSEVIER SCIENCE BV, PO BOX 211, AMSTERDAM, NETHERLANDS, 1000 AE primo editore: BMJ / British Medical Journal Publishing Group:PO Box 299, London WC1H 9TD United Kingdom:011 44 20 73836270, EMAIL: subscriptions@bmjgroup.com, INTERNET: http://www.bmjpg.com/bmj, Fax: 011 44 20 73836402) pp. 73-82 - issn: 0008-6363 - wos: WOS:000278690000012 (40) - scopus: 2-s2.0-77955165005 (42)

11573/229552 - 2010 - Nitric oxide determines mesodermic differentiation of mouse embryonic stem cells by activating class IIa histone deacetylases: potential therapeutic implications in a mouse model of hindlimb ischemia
Spallotta, F; Rosati, J; Straino, S; Nanni, S; Grasselli, A; Ambrosino, V; Rotili, Dante; Valente, Sergio; Farsetti, A; Mai, Antonello; Capogrossi, Mc; Gaetano, C; Illi, B. - 01a Articolo in rivista
rivista: STEM CELLS (Alphamed Press Incorporated:1 Prestige Place, Suite 290:Miamisburg, OH 45342:(937)291-2355, EMAIL: alphamedpress@alphamedpress.com, INTERNET: http://www.alphamedpress.com, Fax: (937)291-4229) pp. 431-442 - issn: 1066-5099 - wos: WOS:000277093700006 (48) - scopus: 2-s2.0-77950581254 (47)

11573/434155 - 2009 - Altered SDF-1-mediated differentiation of bone marrow-derived endothelial progenitor cells in diabetes mellitus
De Falco, Elena; Avitabile, D; Totta, P; Straino, S; Spallotta, F; Cencioni, C; Torella, Ar; Rizzi, R; Porcelli, D; Zacheo, A; Di Vito, L; Pompilio, G; Napolitano, M; Melillo, G; Capogrossi, Mc; Pesce, M. - 01a Articolo in rivista
rivista: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (Bucharest : Foundation for Cellular and Molecular Medicine.) pp. 3405-3414 - issn: 1582-1838 - wos: WOS:000274179300040 (45) - scopus: 2-s2.0-77449146954 (52)

11573/358405 - 2008 - Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling
Illi, B.; Dello Russo, Claudio; Colussi, C.; Rosati, J.; Pallaoro, M.; Spallotta, F.; Rotili, Dante; Valente, Sergio; Ragone, G.; Martelli, F.; Biglioli, P.; Steinkuhler, C.; Gallinari, P.; Mai, Antonello; Capogrossi, M. C.; Gaetano, C. - 01a Articolo in rivista
rivista: CIRCULATION RESEARCH (Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320 PRimo editore: Baltimore, Md. : Grune & Stratton, c1953-) pp. 51-58 - issn: 0009-7330 - wos: WOS:000252217400009 (96) - scopus: 2-s2.0-37849010584 (100)

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