FRANCESCA VALENTE

PhD Graduate

PhD program:: XXXV



Thesis title: The therapeutic effect of behavioural interventions on tic severity for children and adolescents with Tourette Syndrome and Chronic Tic Disorders: a meta-analysis of randomized control trials

Comprehensive Behavioural Intervention for Tics (CBIT), Habit Reversal Training (HRT) and Exposure and Response Prevention (ERP) are forms of behavioural therapy (BT) that can reduce tics in children and adolescents with tic disorders, but the efficacy of these interventions, and of their different types of delivering (face-to-face, group, internet delivering), needs to be clarified. A meta-analysis was performed to evaluate the efficacy of BT for young individuals with Tourette Syndrome (TS) or Chronic Tic Disorders (CTDs). Standard mean differences (SMD) were used as effect size measure to assess the efficacy of BT. Subgroup analyses were performed to identify the potential heterogeneity among studies. A total of 11 randomized controlled trials (RCTs) including 468 patients with TS or CTD were identified for the quantitative analysis. The pooled SMD was 0.551 (95% CI: 0.308−0.794). Overall, it was found a small to medium effect size for the efficacy of BT, suggesting that BT is effective for the treatment of young patients with tic disorders. The individual face-to-face approach seems to be more effective than online approach. Further high-quality RCTs are needed to determine the efficacy of single interventions among behaviour treatments.

Research products

11573/1701266 - 2024 - Comorbidities and Disease Duration in Tourette Syndrome: Impact on Cognition and Quality of Life of Children
Conte, Giulia; Costanza, Carola; Novelli, Maria; Scarselli, Veronica; Arigliani, Elena; Valente, Francesca; Baglioni, Valentina; Terrinoni, Arianna; Chiarotti, Flavia; Cardona, Francesco - 01a Articolo in rivista
paper: CHILDREN (Basel: MDPI AG, 2014-) pp. - - issn: 2227-9067 - wos: WOS:001169920600001 (0) - scopus: 2-s2.0-85187204195 (2)

11573/1678273 - 2022 - Functional Motor Disorders in childhood and adolescence: clinical correlates of an emerging diagnostic challenge.
Baglioni, V.; Conte, G.; Valente, F.; Cardona, F. - 04f Poster
conference: 14th European Conference on Tourette Syndrome and Tic Disorders (Lausanne, Switzerland)
book: ESSTS Book of Abstracts - ()

11573/1616485 - 2022 - Treatment-resistant schizophrenia: Addressing white matter integrity, intracortical glutamate levels, clinical and cognitive profiles between early- and adult-onset patients
Matrone, M.; Kotzalidis, G. D.; Romano, A.; Bozzao, A.; Cuomo, I.; Valente, F.; Gabaglio, C.; Lombardozzi, G.; Trovini, G.; Amici, E.; Perrini, F.; De Persis, S.; Iasevoli, F.; De Filippis, S.; De Bartolomeis, A. - 01a Articolo in rivista
paper: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (Pergamon Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 110493- - issn: 0278-5846 - wos: WOS:000734113300003 (8) - scopus: 2-s2.0-85121096585 (9)

11573/1664935 - 2022 - Treatment-resistant schizophrenia: Addressing white matter integrity, intracortical glutamate levels, clinical and cognitive profiles between early- and adult-onset patients
Matrone, Marta; Kotzalidis, Georgios; Romano, Andrea; Bozzao, Alessandro; Cuomo, Ilaria; Valente, Francesca; Gabaglio, Chiara; Lombardozzi, Ginevra; Trovini, Giada; Amici, Emanuela; Perrini, Filippo; De Persis, Simone. - 01a Articolo in rivista
paper: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (Pergamon Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. - - issn: 0278-5846 - wos: (0) - scopus: (0)

11573/1615731 - 2021 - Le droghe d'abuso e l'emergenza psicopatologica in adolescenza
Conte, Giulia; Gabaglio, Chiara; Pacifici, Susanna; Valente, Francesca; De Filippis, Sergio - 02a Capitolo o Articolo
book: Bambini e adolescenti a «distanza». Il disagio psichico e l'emergenza psicopatologica durante la Pandemia da Covid-19 - (9788865317570)

11573/1474899 - 2020 - Adverse Mental Health Impact of the COVID-19 Lockdown in Individuals With Tourette Syndrome in Italy: An Online Survey
Conte, G.; Baglioni, V.; Valente, F.; Chiarotti, F.; Cardona, F. - 01a Articolo in rivista
paper: FRONTIERS IN PSYCHIATRY (Lausanne, Switzerland: Frontiers Media S.A. All Rights Reserved) pp. - - issn: 1664-0640 - wos: WOS:000598126300001 (27) - scopus: 2-s2.0-85097596072 (33)

11573/1442378 - 2020 - Rage attacks in Tourette syndrome and chronic tic disorder: a systematic review
Conte, Giulia; Valente, Francesca; Fioriello, Francesca; Cardona, Francesco - 01g Articolo di rassegna (Review)
paper: NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 21-36 - issn: 0149-7634 - wos: WOS:000600573400003 (21) - scopus: 2-s2.0-85092207679 (24)

11573/1351623 - 2020 - Children with primary complex motor stereotypies show impaired reactive but not proactive inhibition
Mirabella, Giovanni; Mancini, Christian; Valente, Francesca; Cardona, Francesco - 01a Articolo in rivista
paper: CORTEX (Primo editore: Tipografica Varese, Varese Attuale:Masson SPA:via Flli Bressan 2, I 20126 Milan Italy:011 39 02 27074286, EMAIL: aboonamenti@masson.it, INTERNET: http://www.masson.it, Fax: 011 39 02 27074210) pp. 250-259 - issn: 0010-9452 - wos: WOS:000518434000022 (24) - scopus: 2-s2.0-85077649908 (26)

11573/1256547 - 2019 - Developmental motor profile in preschool children with primary stereotypic movement disorder
Valente, Francesca; Pesola, Chiara; Baglioni, Valentina; Teresa Giannini, Maria; Chiarotti, Flavia; Caravale, Barbara; Cardona, Francesco - 01a Articolo in rivista
paper: BIOMED RESEARCH INTERNATIONAL ([London]: [Hindawi] Cairo: Hindawi Publishing Corporation) pp. -6 - issn: 2314-6133 - wos: WOS:000459652400001 (6) - scopus: 2-s2.0-85062358419 (7)

11573/1619047 - 2018 - Sindrome di Tourette nel bambino
Valente, Francesca; Fioriello, Francesca; Cardona, Francesco Carmelo Giovanni - 02a Capitolo o Articolo
book: Prospettive in Pediatria - ()

11573/905656 - 2016 - Developmental profile and diagnoses in children presenting with motor stereotypies
Cardona, Francesco Carmelo Giovanni; Valente, Francesca; Miraglia, Daniela; D'ardia, Caterina; Baglioni, Valentina; Flavia, Chiarotti - 01a Articolo in rivista
paper: FRONTIERS IN PEDIATRICS (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-2360 - wos: WOS:000388329000001 (6) - scopus: 2-s2.0-85053085037 (7)

11573/1664188 - 2015 - Content of OC symptoms and comorbidities in OCD alone versus tic related ocd children and adolescents
Panunzi, S.; Santoro, F.; Stanca, M.; Giannini, V.; Valente, F.; Cardona, F. - 01h Abstract in rivista
paper: EUROPEAN CHILD & ADOLESCENT PSYCHIATRY (Berlin: Springer, 1992- Seattle Wash.; Bern; Göttingen: Hogrefe & Huber Darmstadt: Steinkopff Verlag Heidelberg: Steinkopff Verlag) pp. 190-191 - issn: 1018-8827 - wos: WOS:000367823900506 (0) - scopus: (0)

11573/463923 - 2012 - Magnetic resonance hysterosalpingography in the evaluation of tubal patency in infertile women: an observational study.
De Felice, Carlo; Rech, Francesco; Marini, A.; Stagnitti, Andrea; Valente, F.; Cipolla, Valentina; Borgogni, G.; Meggiorini, Maria Letizia - 01a Articolo in rivista
paper: CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY (Singapore: IMR Press Montreal: IROG Canada Montreal: S.O.G. Canada) pp. 83-88 - issn: 0390-6663 - wos: WOS:000301509900020 (8) - scopus: 2-s2.0-84860875847 (8)

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