11573/1685968 - 2023 -
An intramolecular energetic network regulates ligand recognition in a SH2 domain Nardella, Caterina; Pagano, Livia; Pennacchietti, Valeria; Felice, Mariana Di; Matteo, Sara Di; Diop, Awa; Malagrinò, Francesca; Marcocci, Lucia; Pietrangeli, Paola; Gianni, Stefano; Toto, Angelo - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:001040354200001 (1) - scopus: 2-s2.0-85166371265 (1)
11573/1686025 - 2023 -
Characterization of the folding and binding properties of the PTB domain of FRS2 with phosphorylated and unphosphorylated ligands Pennacchietti, Valeria; Pagano, Livia; Malagrinò, Francesca; Diop, Awa; Di Felice, Mariana; Di Matteo, Sara; Marcocci, Lucia; Pietrangeli, Paola; Toto, Angelo; Gianni, Stefano - 01a Articolo in rivista
rivista: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (Attuale:ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, USA, NY, 10010-1710
Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 109703- - issn: 0003-9861 - wos: WOS:001053305400001 (0) - scopus: 2-s2.0-85166633882 (0)
11573/1662469 - 2022 -
SH2 Domains: folding, binding and therapeutical approaches Diop, Awa; Santorelli, Daniele; Malagrinò, Francesca; Nardella, Caterina; Pennacchietti, Valeria; Pagano, Livia; Marcocci, Lucia; Pietrangeli, Paola; Gianni, Stefano; Toto, Angelo - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 15944- - issn: 1422-0067 - wos: WOS:000902565100001 (5) - scopus: 2-s2.0-85144969444 (4)
11573/1652072 - 2022 -
Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat Malagrinò, Francesca; Fusco, Giuliana; Pennacchietti, Valeria; Toto, Angelo; Nardella, Caterina; Pagano, Livia; De Simone, Alfonso; Gianni, Stefano - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:000840110600001 (2) - scopus: 2-s2.0-85137125864 (3)
11573/1651291 - 2022 -
Folding and binding mechanisms of the SH2 domain from Crkl Nardella, Caterina; Toto, Angelo; Santorelli, Daniele; Pagano, Livia; Diop, Awa; Pennacchietti, Valeria; Pietrangeli, Paola; Marcocci, Lucia; Malagrinò, Francesca; Gianni, Stefano - 01a Articolo in rivista
rivista: BIOMOLECULES (Basel: MDPI) pp. 1014- - issn: 2218-273X - wos: WOS:000846180000001 (4) - scopus: 2-s2.0-85137360513 (4)
11573/1657644 - 2022 -
Exploring the effect of tethered domains on the folding of Grb2 protein Pagano, Livia; Pennacchietti, Valeria; Diop, Awa; Santorelli, Daniele; Pietrangeli, Paola; Marcocci, Lucia; Nardella, Caterina; Malagrinò, Francesca; Toto, Angelo; Gianni, Stefano - 01a Articolo in rivista
rivista: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (Attuale:ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, USA, NY, 10010-1710
Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 109444- - issn: 0003-9861 - wos: WOS:000880049100004 (1) - scopus: 2-s2.0-85141826263 (2)
11573/1593241 - 2021 -
Unveiling induced folding of intrinsically disordered proteins - Protein engineering, frustration and emerging themes Malagrinò, Francesca; Diop, Awa; Pagano, Livia; Nardella, Caterina; Toto, Angelo; Gianni, Stefano - 01a Articolo in rivista
rivista: CURRENT OPINION IN STRUCTURAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 160-160 - issn: 0959-440X - wos: WOS:000768730600018 (8) - scopus: 2-s2.0-85120903843 (12)
11573/1577022 - 2021 -
Determining folding and binding properties of the C-terminal SH2 domain of SHP2 Nardella, Caterina; Malagrinò, Francesca; Pagano, Livia; Rinaldo, Serena; Gianni, Stefano; Toto, Angelo - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:000705532500001 (5) - scopus: 2-s2.0-85116539527 (5)
11573/1579282 - 2021 -
Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer Nardella, Caterina; Visconti, Lorenzo; Malagrinò, Francesca; Pagano, Livia; Bufano, Marianna; Nalli, Marianna; Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano; Gianni, Stefano; Toto, Angelo - 01a Articolo in rivista
rivista: BIOLOGY DIRECT (London: BioMed Central) pp. - - issn: 1745-6150 - wos: WOS:000706722300001 (8) - scopus: 2-s2.0-85117321017 (9)
11573/1552783 - 2021 -
Probing the effects of local frustration in the folding of a multidomain protein Pagano, Livia; Malagrinò, Francesca; Visconti, Lorenzo; Troilo, Francesca; Pennacchietti, Valeria; Nardella, Caterina; Toto, Angelo; Gianni, Stefano - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD,
-London; New York: Academic Press.) pp. 167087- - issn: 0022-2836 - wos: WOS:000672680300017 (6) - scopus: 2-s2.0-85107967375 (6)
11573/1477086 - 2021 -
Double mutant cycles as a tool to address folding, binding, and allostery Pagano, Livia; Toto, Angelo; Malagrinò, Francesca; Visconti, Lorenzo; Jemth, Per; Gianni, Stefano - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 828- - issn: 1422-0067 - wos: WOS:000611298300001 (6) - scopus: 2-s2.0-85099547793 (11)
11573/1495668 - 2021 -
Folding and misfolding of a PDZ tandem repeat Visconti, Lorenzo; Malagrinò, Francesca; Troilo, Francesca; Pagano, Livia; Toto, Angelo; Gianni, Stefano - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD,
-London; New York: Academic Press.) pp. 166862- - issn: 0022-2836 - wos: WOS:000630007900009 (7) - scopus: 2-s2.0-85100673226 (8)
11573/1435307 - 2020 -
Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate Gautier, Candice; Troilo, Francesca; Cordier, Florence; Malagrinò, Francesca; Toto, Angelo; Visconti, Lorenzo; Zhu, Yanlei; Brunori, Maurizio; Wolff, Nicolas; Gianni, Stefano - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 19963-19969-19969 - issn: 0027-8424 - wos: WOS:000567818600007 (12) - scopus: 2-s2.0-85089787733 (13)
11573/1456152 - 2020 -
Targeting the interaction between the SH3 domain of Grb2 and Gab2 Malagrinò, Francesca; Coluccia, Antonio; Bufano, Marianna; La Regina, Giuseppe; Puxeddu, Michela; Toto, Angelo; Visconti, Lorenzo; Paone, Alessio; Magnifico, Maria Chiara; Troilo, Francesca; Cutruzzolà, Francesca; Silvestri, Romano; Gianni, Stefano - 01a Articolo in rivista
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 2435- - issn: 2073-4409 - wos: WOS:000592940700001 (6) - scopus: 2-s2.0-85096028884 (5)
11573/1401198 - 2020 -
Understanding the binding induced folding of intrinsically disordered proteins by protein engineering: caveats and pitfalls Malagrinò, Francesca; Visconti, Lorenzo; Pagano, Livia; Toto, Angelo; Troilo, Francesca; Gianni, Stefano - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 3484- - issn: 1422-0067 - wos: WOS:000539312100080 (8) - scopus: 2-s2.0-85084964055 (9)
11573/1359552 - 2020 -
Unveiling the molecular basis of the noonan syndrome-causing mutation T42A of SHP2 Toto, A.; Malagrino, F.; Visconti, L.; Troilo, F.; Gianni, S. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 461- - issn: 1661-6596 - wos: WOS:000515380000091 (6) - scopus: 2-s2.0-85077880233 (8)
11573/1435303 - 2020 -
Comparing the binding properties of peptides mimicking the envelope protein of sars-cov and sars-cov-2 to the pdz domain of the tight junction-associated pals1 protein Toto, Angelo; Ma, Sana; Malagrinò, Francesca; Visconti, Lorenzo; Pagano, Livia; Stromgaard, Kristian; Gianni, Stefano - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:000566781500001 (32) - scopus: 2-s2.0-85090470025 (37)
11573/1401188 - 2020 -
Templated folding of intrinsically disordered proteins Toto, Angelo; Malagrinò, Francesca; Visconti, Lorenzo; Troilo, Francesca; Pagano, Livia; Brunori, Maurizio; Jemth, Per; Gianni, Stefano - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 6586-6593 - issn: 0021-9258 - wos: WOS:000537685000027 (44) - scopus: 2-s2.0-85084721842 (40)
11573/1359561 - 2020 -
The effect of proline cis‐trans isomerization on the folding of the C‐terminal SH2 domain from p85 Troilo, F.; Malagrino, F.; Visconti, L.; Toto, A.; Gianni, S. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 125- - issn: 1661-6596 - wos: WOS:000515378000125 (4) - scopus: 2-s2.0-85077263439 (5)
11573/1417653 - 2020 -
Understanding the mechanism of recognition of gab2 by the n-sh2 domain of shp2 Visconti, Lorenzo; Malagrinò, Francesca; Pagano, Livia; Toto, Angelo - 01a Articolo in rivista
rivista: LIFE (Basel: MDPI) pp. 85- - issn: 2075-1729 - wos: WOS:000551223300004 (7) - scopus: 2-s2.0-85090739226 (7)
11573/1399303 - 2020 -
Demonstration of binding induced structural plasticity in a sh2 domain Visconti, Lorenzo; Toto, Angelo; Jarvis, James A.; Troilo, Francesca; Malagrinò, Francesca; De Simone, Alfonso; Gianni, Stefano - 01a Articolo in rivista
rivista: FRONTIERS IN MOLECULAR BIOSCIENCES (Lausanne : Frontiers Media S.A., 2014-) pp. - - issn: 2296-889X - wos: WOS:000537268200001 (5) - scopus: (0)
11573/1336078 - 2019 -
Mapping the allosteric network within a SH3 domain Malagrinò, F.; Troilo, F.; Bonetti, D.; Toto, A.; Gianni, S. - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature
London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000470075600028 (13) - scopus: 2-s2.0-85066618062 (16)
11573/1221373 - 2019 -
Hydrogen sulfide oxidation: adaptive changes in mitochondria of sw480 colorectal cancer cells upon exposure to hypoxia Malagrinò, Francesca; Zuhra, Karim; Mascolo, Ludovica; Mastronicola, Daniela; Vicente, João B.; Forte, Elena; Giuffrè, Alessandro - 01a Articolo in rivista
rivista: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (London: Hindawi
AUSTIN, USA, TX: LANDES BIOSCIENCE) pp. 1-11 - issn: 1942-0900 - wos: WOS:000458436600001 (24) - scopus: 2-s2.0-85062596718 (31)
11573/1336088 - 2019 -
Binding induced folding: Lessons from the kinetics of interaction between NTAIL and XD Toto, A.; Troilo, F.; Visconti, L.; Malagrinò, F.; Bignon, C.; Longhi, Sonia Rachele Agata; Gianni, S.; S, - 01a Articolo in rivista
rivista: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (Attuale:ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, USA, NY, 10010-1710
Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 255-261 - issn: 0003-9861 - wos: WOS:000525438900029 (4) - scopus: 2-s2.0-85069557296 (4)
11573/1336085 - 2019 -
Structural characterization of an on-pathway intermediate and transition state in the folding of the N-terminal SH2 domain from SHP2 Visconti, L.; Malagrinò, F.; Gianni, S.; Toto, A. - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 4769-4777 - issn: 1742-4658 - wos: WOS:000499718600012 (6) - scopus: 2-s2.0-85069838702 (8)
11573/1218458 - 2019 -
Investigating the molecular basis of the aggregation propensity of the pathological d76n mutant of beta-2 microglobulin: role of the denatured state Visconti, L; Malagrinò, F; Broggini, L; De Luca, Cmg; Moda, F; Gianni, S; Ricagno, S; Toto, A. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000459746500164 (5) - scopus: 2-s2.0-85060402058 (5)
11573/1253355 - 2019 -
The kinetics of folding of the NSH2 domain from p85 Visconti, Lorenzo; Malagrinò, Francesca; Toto, Angelo; Gianni, Stefano - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature
London: Nature Publishing Group) pp. 4058- - issn: 2045-2322 - wos: WOS:000460751700013 (9) - scopus: 2-s2.0-85062766339 (9)
11573/1315822 - 2019 -
N-acetylcysteine serves as substrate of 3-mercaptopyruvate sulfurtransferase and stimulates sulfide metabolism in colon cancer cells Zuhra, Karim; Tomé, Catarina S; Masi, Letizia; Giardina, Giorgio; Paulini, Giulia; Malagrinò, Francesca; Forte, Elena; Vicente, João B; Giuffrè, Alessandro - 01a Articolo in rivista
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 828- - issn: 2073-4409 - wos: WOS:000484537500061 (28) - scopus: 2-s2.0-85079506342 (31)
11573/1089712 - 2018 -
The presence of glutamate residues on the PAS sequence of the stimuli-sensitive nano-ferritin improves in vivo biodistribution and mitoxantrone encapsulation homogeneity Falvo, Elisabetta; Malagrinò, Francesca; Arcovito, Alessandro; Fazi, Francesco; Colotti, Gianni; Tremante, Elisa; Di Micco, Patrizio; Braca, Aldo; Opri, Roberta; Giuffrè, Alessandro; Fracasso, Giulio; Ceci, Pierpaolo - 01a Articolo in rivista
rivista: JOURNAL OF CONTROLLED RELEASE (Controlled Release Society:13355 Tenth Avenue, Suite 108:Minneapolis, MN 55441:(763)512-0909, EMAIL: registration@ardel.com) pp. 177-185 - issn: 0168-3659 - wos: WOS:000428412400016 (38) - scopus: 2-s2.0-85042431671 (41)
11573/1159789 - 2018 -
A carboxylate to amide substitution that switches protein folds Gianni, Stefano; Mccully, Michelle E.; Malagrinò, Francesca; Bonetti, Daniela; De Simone, Alfonso; Brunori, Maurizio; And Valerie Daggett, - 01a Articolo in rivista
rivista: ANGEWANDTE CHEMIE. INTERNATIONAL EDITION (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 12795-12798 - issn: 1433-7851 - wos: WOS:000444941600032 (3) - scopus: 2-s2.0-85053053524 (3)
11573/1115381 - 2018 -
H 2 S metabolism in colon cancer cells: Effect of hypoxia Malagrinò, Francesca; Zuhra, Karim; Mastronicola, Daniela; Mascolo, Ludovica; Vicente, João B.; Forte, Elena; Giuffrè, Alessandro - 01h Abstract in rivista
rivista: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. S160- - issn: 0891-5849 - wos: WOS:000432836500513 (1) - scopus: (0)
11573/1254479 - 2018 -
H2S metabolism in colon cancer cells exposed to hypoxia Zuhra, Karim; Malagrinò, Francesca; Mascolo, Ludovica; Mastronicola, Daniela; Vicente, João B.; Forte, Elena; Giuffrè, Alessandro - 04d Abstract in atti di convegno
congresso: Therapeutic Applications of Nitric Oxide in Cancer and Inflammatoryrelated Disorders (Accademia dei Fisiocritici (Siena))
libro: Therapeutic application of nitric oxide in cancer and inflammatory disorders - (9780128165454)
11573/1114976 - 2017 -
A clinically relevant variant of the human hydrogen sulfide-synthesizing enzyme cystathionine β -synthase: increased CO eactivity as a novel molecular mechanism of pathogenicity? Vicente, João B; Colaço, Henrique G.; Malagrinò, Francesca; Santo, Paulo E.; Gutierres, André; Bandeiras, Tiago M.; Leandro, Paula; Brito, José A.; Giuffre', Alessandro - 01a Articolo in rivista
rivista: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (London: Hindawi
AUSTIN, USA, TX: LANDES BIOSCIENCE) pp. - - issn: 1942-0900 - wos: WOS:000398255100001 (15) - scopus: 2-s2.0-85017139205 (14)
11573/934979 - 2016 -
N-methylated α-amino acids and peptides: synthesis and biological activity Di Gioia, Maria Luisa; Leggio, Antonella; Malagrinò, Francesca; Romio, Emanuela; Siciliano, Carlo; Liguori, Angelo - 01a Articolo in rivista
rivista: MINI-REVIEWS IN MEDICINAL CHEMISTRY (Hilversum : Bentham Science Publishers) pp. 683-90- - issn: 1875-5607 - wos: WOS:000374121300001 (50) - scopus: 2-s2.0-84964258797 (56)
11573/902004 - 2016 -
Bioenergetic relevance of hydrogen sulfide and the interplay between gasotransmitters at human cystathionine β-synthase Vicente, João B; Malagrinò, Francesca; Arese, Marzia; Forte, Elena; Sarti, Paolo; Giuffre', Alessandro - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1127-1138 - issn: 0005-2728 - wos: WOS:000378179300011 (40) - scopus: 2-s2.0-84975501003 (43)