FLAVIA CATALANO

PhD Student

PhD program:: XXXVII
email: flavia.catalano@uniroma1.it
phone: 3220236
building: Dipartimento di scienze Biochimiche "A. Rossi-Fanelli"
room: T4




supervisor: Carlo Travaglini Allocatelli
co-supervisor: Carlo Travaglini Allocatelli

Research: Biochemical characterization of the KH domains of FMRP, a protein involved in X-fragile syndrome

Education:
- PhD in Biochemistry (XXXVII cycle) at “La Sapienza” University of Rome, Rome, Italy.
- October 2021: Master’s Degree in Pharmaceutical Biotechnology (LM-9) at “La Sapienza” University of Rome, Rome, Italy. Final grade: 110 cum laude / 110
Final thesis: "Folding characterization of the KH1 domain of FMRP, a protein involved in X-Fragile syndrome, and its pathological mutant"
- October 2019: Bachelor’s Degree in Applied Pharmaceutical Science (L-29) at “La Sapienza” University of Rome, Rome, Italy. Final grade: 109/110
Final thesis: "Design, purification, and thermodynamic and structural characterization of a site-specific mutant of BrD2, a protein involved in the regulation of protein expression"
- July 2016: Upper Secondary School Diploma in Classical and Ancient Studies (Maturitá Classica) at Liceo Classico statale Pilo Albertelli, Rome, Italy.

Language skills:
Italian (native proficiency)
English (B1)

IT skills:
Microsoft Office package, Chimera, CCP4, Wincoot, Phoenix, Prism Graphpad, Kaleidagraph, 3DQSar, Marvinsketch, Ligandscout.

Laboratory skills:
Bacterial cultures, mutagenesis, expression and purification of recombinant proteins, chromatographic techniques, SDS-PAGE electrophoresis, UV-VIS absorption spectroscopy, Circular Dicroism Spectroscopy, Fluorescence Spectroscopy.

Research products

11573/1713419 - 2024 - Conformational and dynamic properties of the KH1 domain of FMRP and its fragile X syndrome linked G266E variant
Catalano, Flavia; Santorelli, Daniele; Astegno, Alessandra; Favretto, Filippo; D’Abramo, Marco; Del Giudice, Alessandra; De Sciscio, Maria Laura; Troilo, Francesca; Giardina, Giorgio; Di Matteo, Adele; Travaglini-Allocatelli, Carlo - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (Tokyo ; Oxford ; New York ; London ; Amsterdam ; Shannon ; Paris : Elsevier) pp. 1-8 - issn: 1570-9639 - wos: WOS:001233726500001 (0) - scopus: 2-s2.0-85190942366 (0)

11573/1697907 - 2023 - Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study
Cellini, Barbara; Pampalone, Gioena; Camaioni, Emidio; Pariano, Marilena; Catalano, Flavia; Zelante, Teresa; Dindo, Mirco; Macchioni, Lara; Di Veroli, Alessandra; Galarini, Roberta; Paoletti, Fabiola; Davidescu, Magdalena; Stincardini, Claudia; Vascelli, Gianluca; Bellet, Marina Maria; Saba, Julie; Giovagnoli, Stefano; Giardina, Giorgio; Romani, Luigina; Costantini, Claudio - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 22692- - issn: 2045-2322 - wos: WOS:001131702800073 (1) - scopus: 2-s2.0-85180264820 (1)

11573/1662111 - 2022 - Folding characterization of the KH1 domain of FMRP, a protein involved in X-Fragile syndrome, and its pathological mutant.
Catalano, Flavia; Travaglini Allocatelli, Carlo; Di Matteo, Adele; Santorelli, Daniele - 04d Abstract in atti di convegno
conference: 33rd "A. Castellani" Meeting of PhD students in biochemical sciences (Brallo di Pregola (PV))
book: 33rd "A. Castellani" Meeting of PhD students in biochemical sciences abstract book - ()

11573/1661961 - 2022 - Folding mechanism and aggregation propensity of the KH0 domain of FMRP and its R138Q pathological variant
Santorelli, Daniele; Troilo, Francesca; Fata, Francesca; Angelucci, Francesco; Demitri, Nicola; Giardina, Giorgio; Federici, Luca; Catalano, Flavia; Di Matteo, Adele; Travaglini-Allocatelli, Carlo - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 12178- - issn: 1422-0067 - wos: WOS:000875286300001 (1) - scopus: 2-s2.0-85140969018 (1)

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