Research: Development of a microfluidic printhead for 3D bioprinting of human tissue models in vitro
*RESEARCH INTERESTS*
• Microfluidics
• 3D printing
• Bioprinting
• Biomaterials
• Cell culture
• Image processing
• Numerical simulations on fluid dynamics (CFD)
• Ultrasound-induced triggering of biological effects
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*EDUCATION*
- MSC IN BIOMEDICAL ENGINEERING | ROMA TRE UNIVERSITY | OCT 2017–MAR 2020
Thesis: “A novel platform for live observation of endothelial cells (HUVEC) morphodynamics during endothelial barrier formation”
Advisor: Prof.ssa Gabriella Cincotti, Roma Tre University and Prof. Carlo Massimo Casciola, Sapienza University
Outline: Study on endothelial cells culture in a microfluidic device and observation of cellular morphodynamics
during physiological growth.
Vote: 110/110 cum laude
- ERASMUS+ PROGRAM | NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU) | AUG – DEC 2018
Attended master courses: Biophysical Micromethods, Medical Imaging, Molecular biophysics and Nanomedicine.
- BSC IN ELECTRICAL ENGINEERING | ROMA TRE UNIVERSITY | OCT 2014 – DEC 2017
Thesis: “Colorimetric technology for the monitoring of water samples – Spectrophotometric measurements for
the evaluation of water pH”
Advisor: Prof.ssa Gabriella Cincotti, Roma Tre University
Outline: pH measurement of water samples through colorimetry technologies and spectrophotometer.
Vote: 110/110 cum laude
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*EXPERIENCES AND ACCOMPLISHMENTS*
- PHD IN THEORETICAL AND APPLIED MECHANICS | UNIVERSITY OF ROME “LA SAPIENZA” | NOV 2020 – PRESENT
In collaboration with the Center for Life Nano and Neuro Science (CLN2S), Fondazione Istituto Italiano di
Tecnologia (IIT).
Project: “Harnessing novel microfluidic platform for the biofabrication of 3D complex in vitro tissues”
Advisor: Prof. Carlo Massimo Casciola, Sapienza University
Outline: Development of a novel protocol for the fabrication of microfluidic devices in PDMS via advanced 3D printing methods. Characterisation and exploitation of microfluidic devices as printheads for the fabrication via 3D bioprinting approach of hierarchical and functional tissue substitutes for the regeneration of musculoskeletal defects.
- EXHIBITOR | MAKER FAIRE – VIII EDITION | 10-13 DEC 2020
Presentation of a 3D-printed sonication chamber for the observation of US-triggered biological effects
- MSC TRAINEESHIP | CLN2S@SAPIENZA, IIT | SEPT 2019 – MAR 2020
Realization of microfluidic devices in PDMS through soft lithography techniques.
Biological functionalization of microfluidic devices. Insertion and culture of endothelial cells (HUVECs) and image acquisition through spinning-disk confocal microscope. Image processing and analysis of cell morphodynamics.
- BSC TRAINEESHIP | ROMA TRE CHEMISTRY LAB (CISDIC) | SEP – DEC 2017
Performed spectrophotometric measures through We-Lab photometer unit. Sample preparation, building of the
calibration curve and acquisition of unknown samples. Basic chemistry lab security formation.
- COLLABORATOR | ROMA TRE SCIENTIFIC LIBRARY | IN 2015/2016, 2016/2017 AND 2019/2020 A.Y.
Provided support to library operators.
Acquired knowledge on Dewey Decimal Classification (DDC).
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*SKILLS*
BIOENGEINEERING
- Fabrication of microfluidic devices via 3D printing and soft lithography.
- Image acquisition through different microscopes (Fast cam microscope, Confocal Laser Scanning, Confocal Spinnin Disk)
- Micro Particle Image Velocimetry (uPIV) measurements.
- Culture of A549 and HUVECs cell lines and Human Bone Marrow Stem Cells (hBMSCs).
SOFTWARE
- Familiar with CAD software (Fusion 360®, Rhinoceros 6).
- Expert in data analysis with MATLAB®
- Experti in image processing with ImageJ® and image editing with Adobe Illustrator®.
- Experience in Raspberry Pi and Arduino programming (C/C++)
- Basic knowledge of CFD simulation software as FLUENT (Ansys®) and COMSOL Multiphysics®.