FEDERICA SQUILLANTE

PhD Student

PhD program:: XL
email: federica.squillante@uniroma1.it
phone: 3891524034
building: Dipartimento di Medicina Molecolare, Edificio RM110, Palazzina B
room: IV piano, Stanza 404




supervisor: Prof.ssa Maria Pia Felli
advisor: Prof.ssa Maria Pia Felli
co-supervisor: Prof.re Giuseppe Giannini

Research: Blocking oncogenic notch signaling with serca inhibitors in t-cell acute lymphoblastic leukemia

EDUCATION & TRAINING:

October 2024 – November 2024: Training course in
"Preclinical Experimentation and Animal Welfare" University of Rome La Sapienza.

1/11/24- ongoing: PhD in Molecular Medicine
University of Rome, La Sapienza, piazzale Aldo Moro 5, 00185, Rome.

1/11/2023-16/10/24: Experimental thesis
Department of Experimental Medicine, Viale Regina Elena 291, 00161, Rome.
Thesis title: "Role of microRNAs in the progression of Notch-dependent T-cell acute lymphoblastic leukemia".
External supervisor: Prof. Felli Maria Pia
Internal supervisor: Prof. Fiorillo Maria Teresa

1/10/2022-16/10/2024: Master's Degree in Genetics and Molecular Biology
University of Rome, La Sapienza- Department of Biology
and Biotechnology "Charles Darwin"
Graduation date: 16/10/2024
Final grade: 110/110 laude.

1/10/2019-26/10/2022: First cycle degree in Biotechnology [L-270 - Order 2019] (class L-2)
University of Rome, La Sapienza- Department of Biology
and Biotechnology "Charles Darwin"
Thesis title: "Characterization of CRISPR/Cas9-induced Tel mutants influencing telomere elongation in Drosophila"
Speaker: Prof.re Giovanni Cenci
Graduation date: 26/10/2022
Final grade: 110/110 laude

2014-2019: Five-year Diploma
Liceo Scientifico "Nicola Sensale" - Via S. D'Alessandro, 84014 Nocera Inferiore (SA).
Final grade: 100/100

INVESTMENTS:

02/12/2024-04/12/2024: CONGRESS: 36th AICC International Meeting 2024
Hijacking the good pathways: cancer, immunity and therapeutic approaches.
University of Rome La Sapienza.

PERSONAL SKILLS AND COMPETENCES:

- Statistical skills with SPSS and ANOVA
- Bioinformatics skills (Pymol)
- Knowledge and experience with RNA/DNA extraction and protein extraction
- PCR and qRT-PCR analysis
- Cell culture expertise
- Experience in basic molecular biology techniques
- Experience in functional genomics (miRNA)
- Western blot technique.
- Neon system Transfection
- Flow Cytometry Analysis
- Processing of organs and tissues from mouse models
genetically modified
- Pharmacological treatments.

Mother tongue: ITALIAN

Other languages: ENGLISH
- Reading skills: B1
- Writing skills: B1
- Oral expression skills: B1

SKILLS:

- In-depth knowledge of Windows, OsX platforms.
- Excellent knowledge of the Office package and skills in databases regarding design, implementation, implementation and archiving.
- Excellent knowledge of email services and the most common browsers.
- Competence in the use of the Pymol program for the visualization of protein structure.

I authorize the processing of my personal data pursuant to Legislative Decree 30
June 2003, no. 196 "Code regarding the protection of personal data.

Research products

11573/1746515 - 2025 - Bladder cancer: uncovering the predictive role of NOTCH as an emerging candidate biomarker for therapeutic strategies
Cusumano, Chiara; Squillante, Federica; Roma, Marco; Miano, Roberto; Felli, Maria Pia - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. 3078- - issn: 2072-6694 - wos: WOS:001579677600001 (0) - scopus: 2-s2.0-105017002355 (0)

11573/1729233 - 2024 - Notch inhibitors and BH3 mimetics in T-cell acute lymphoblastic leukemia
Sergio, Ilaria; Varricchio, Claudia; Squillante, Federica; Cantale Aeo, Noemi Martina; Campese, Antonio Francesco; Felli, Maria Pia - 01g Articolo di rassegna (Review)
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:001377194600001 (3) - scopus: 2-s2.0-85211824937 (3)



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