EUGENIO BARONE

Full professor

email: eugenio.barone@uniroma1.it
phone: 0649910885
building: CU027
room: 312

Personal Statement
Dysfunction of neurotrophic signaling in the brain is a common pathophysiological mechanism leading to cognitive decline in a number of conditions including ageing, neurodegenerative disorders (Alzheimer disease, AD), genetic disorders (Down syndrome, DS) and metabolic diseases (obesity and type 2diabetes mellitus, T2DM). Insulin and GLP1 signalling act as key regulators for gene expression and cellular metabolism, both events sustaining neuronal activity and synaptic plasticity mechanisms. These neurotrophic signaling also control oxidative metabolism via mitochondrial dynamics, thus protecting neurons against oxidative damage. Actions of insulin and GLP1 in the brains of healthy individuals include central modulation of body metabolism and enhancement or regulation of memory and learning functions. Alterations of brain insulin signalling are early pathogenic events associated with ageing and the development of neurodegenerative disorders, while GLP1 and GLP1 mimetics appear promising candidates in overcoming brain insulin signaling dysfunctions. The overarching goal of my laboratory is to use multidisciplinary approaches to clarify defects of neurotrophic signaling during ageing and neurodegeneration.

Positions
2023-present: Full Professor of Biochemistry, Dept. of Biochemical Sciences, Sapienza Univ. of Rome
2019–2023 Associate Professor of Biochemistry, Dept. of Biochemical Sciences, Sapienza Univ. of Rome
2017–present: Faculty Board - PhD in Biochemistry, Sapienza Univ. of Rome
2016–2019: Assistant Professor of Biochemistry, Dept. of Biochemical Sciences, Sapienza Univ. of Rome
2015–2018: Associate Researcher, Univ. Autonoma de Chile, Santiago, CL
2014–2016: PostDoc, Dept. of Biochemical Sciences, Sapienza Univ. of Rome
Funded by: Marie Curie Fellow, People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013)
01/2012–12/2013: PostDoc, Brain Mind Institute, EPFL, Lausanne, CH
02/2011–07/2011: PostDoc, Inst. of Pharmacology, Catholic Univ. School of Medicine Rome, IT
01/2010–12/2010: Research Scholar (as part of the PhD Program in Neuroscience) at (a) Dept. of Biomedical Pharmacology in the Sanders-Brown Center on Aging (Supervisor Prof. Elizabeth Head) and (b) Dept. of Chemistry, Laboratory of Neurochemistry (Supervisor Prof. D. Allan Butterfield), Univ. of Kentucky, Lexington, Kentucky, USA.
11/2007-02/2011: PhD Candidate in Neuroscience, Inst. of Pharmacology, Catholic Univ. School of Medicine, Rome
12/2006: National Qualification as Pharmacist, University of Calabria, Arcavacata di Rende (CS), IT
05/2006: Master degree in Pharmaceutical Chemistry and Technology (summa cum laude)
Faculty of Pharmacy, University of Calabria, Arcavacata di Rende (CS), IT
01/2004–06/2004: Visiting student (ERASMUS Project), Universitè Paris Descartes, Paris, FR

Appointments and Honors
2023-present: Appointed as member of the European College of Neuropsychopharmacology (ECNP)
2022-2024: Appointed as Chair of the “Strategic Alliances & Outreach” committee of the Society for Redox Biology and Medicine (SfRBM)
2022-2024: Chair of the Local Committee responsible for the organization fo the Trisomy 21 Research Society (T21RS) International Meeting to be held in Rome in 2024, IT.
2022: Elected as Executive Board member of the Trisomy 21 Research Society (T21RS)
2021: Chair, selected symposium “Role of insulin signaling in the brain metabolism”, Brain & Brain PET 2021 international conference, Glasgow, 26 – 29 June 2021.
2020-2023: Appointed as Chair of the SfRBM “Awards-Junior” committee
2020-2023: Elected as SfRBM Council member
2020: Appointed as member of the European Brain Research Area (EBRA) for the Trisomy 21 cluster.
2020: Member of the Scientific Committee responsible for the organization of the IV Italian National conference on Down Syndrome. 16-17 October 2020.
2020: Member of the scientific committee for the evaluation of Jerome-Lejeune Foundation research Grants
2020: Appointed as Associate Editor for Antioxidants
2020: Appointed as Associate Editor for Frontiers in Neuroscience
2019-present: Member of the "Daniel Bovet" Neurobiology Research Center Sapienza Univ. of Rome
2020-present: Reviewer for the Medical Research Council (MRC, United Kingdom) grants
2019-present: Reviewer for the National Science Centre in Poland
2019: Nominated official consultant for Bio-Rad® Laboratories
2019-present: Guest Editor for 2 Special Issues edited by Antioxidants journal.
2019: Organizer and Chair of the Symposium: Metabolic defects in Down syndrome: from periphery to the brain. 3rd International Meeting of the Trisomy 21 Research Society, Barcelona, Spain, 5-9 June, 2019.
2018 - present: Organizer and Chair of a series of seminars for the PhD School in Biochemistry and for Daniel Bovet Neurobiology Research Center at Sapienza University of Rome
2018-2019: Topic Editor for Frontiers in Neuroscience
2017 - present: Reviewer for the Alzheimer ‘s Association Research Grant Program
2017 - present: Reviewer for the SfRBM Annual Meeting Program
2016-2019: Member of the SfRBM External Marketing/PR Committee
2014: Guest Editor for Current Alzheimer Research
2013 - present: Member of the Editorial Board of Neural Regeneration Research
2012 - present: Young European Assessor, Italian Medicines Agency (AIFA)

International Fellowships and Awards
03/2014 – 02/2016: Marie Curie Fellowship for PostDoc, funded by the European Union's Seventh Framework Programme (FP7/2007-2013) (rating 93.50/100, excellent) Dept. of Biochemical Sciences, Sapienza Univ. of Rome
06/2010–11/2010: SfRBM Fellowship Award, Dept. of Chemistry, Lab of Neurochemistry, Univ. of Kentucky, Lexington (KY), USA. Supervisor: Prof. D. Allan Butterfield
06/2018: 2018 Best Poster Award, Society for Free Radical Research International Conference, Lisbon, PT
06/2017: T21RS Travel Award, Trisomy 21 Research Society Conference, Chicago (IL), USA
06/2017: AAIC Travel Fellowship, International Conference 2017, London, UK
11/2016: SFRBM travel Award, Annual Meeting, San Francisco (CA), USA
11/2015: SFRBM travel Award, Annual Meeting, Boston (MA), USA
06/2013: EPHAR Fellowship Award, Federation of the European Pharmacological Society
10/2010: Selected among the best young talents at the Catholic University School of Medicine, Rome, IT
10/2009: Best Poster Award, 34th National Congress of the Italian Society of Pharmacology

Memberships of Scientific Societies
European Association for the Study of Diabetes (EASD), European Society for Neurochemistry (ESN)
International Society of Neurochemistry (ISN), International Society to Advance Alzheimer's Research and Treatment (ISTAART), Trisomy21 Research Society (T21RS), Society for Redox Biology and Medicine (SfRBM), Italian Society of Biochemistry (SIB)

Teaching Experiences
@ Faculty of Pharmacy and Medicine, Sapienza University of Rome, Rome, Italy:
2018– present: Laboratory Safety Course for the PhD students in Biochemistry
2018– present: Professor of Biochemistry, Degree in Audioprothesic Techniques
2018– present: Professor of Biochemistry, Degree in Audiometric Techniques
2017– present: Professor of Biochemistry, Degree in Nursing
2016– present: Professor of Biochemistry, Degree in Medicine
2016– present: Professor of Biochemistry, Residency in Neurology
@ Brain Mind Institute, Swiss Federal Institute of Technology (EPFL), Lausanne, CH:
2012 – 2014: Laboratory training and supervision of master students enrolled at the School of Life Science

Invited presentations at National and International Conferences
Invited to present at 40 National or International Conferences from 2009 to 20222, among which:

2023: International Society for Neurochemistry (ISN), 2023 ISN-ESN biennial Meeting. Aberrant insulin signalling alters mitochondrial bioenergetics and cell stress response in the brain: a route toward neurodegeneration.
2022: International Conference. More than Neurons: changing the paradigm for novel therapeutic avenues. Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal-derived extracellular vesicles.
2022: Dementia Therapeutics and Cognitive Rehabilitation Scientific Meeting. Neural-derived extracellular vesicles (nEVs): a novel approach to identify brain alterations leading to Alzheimer disease.
2022: SfRBM 29th Annual Conference. Loss Of Biliverdin Reductase-A (BVR-A) Impairs Brain Energy Metabolism Favoring The Development Of Neurodegeneration: A Link Between AD And T2DM.
2022: 10th Croatian Congress of Pharmacology. Crosstalk between oxidative stress and aberrant insulin signalling in the brain: insights for neurodegeneration.
2022: T21RS 4th International meeting. Aberrant crosstalk between insulin signaling and mTOR in young down syndrome individuals revealed by neuronal-derived extracellular vesicles.
2022: Brain & Brain PET 2021. Role of early alterations of brain insulin signaling in neurodegenerative processes.
2021: SfRBM annual meeting. Insulin signalling regulates mitochondrial bioenergetics in the brain: insight for the development of neurodegenerative diseases
2021: Global Association for the Study of Neurodegenerative Diseases, INC. (GASND) first International Meeting. Oxidative stress links brain insulin resistance and mitochondrial defects in Down syndrome brain early in life: implication for neurodegeneration.
2020: SfRBM annual meeting. Oxidative stress links brain insulin resistance and mitochondrial defects in Down syndrome brain early in life: implication for neurodegeneration.
2020: AAIC annual meeting. Loss of biliverdin reductase-A (BVR-A) impairs beneficial effects of CNS insulin on brain energy metabolism favoring the development of Alzheimer's disease (AD) neuropathology.
2020: 11th International Conference on Heme Oxygenase and Related Enzymes. Biliverdin reductase-A at the crossroad between insulin signaling and energy metabolism: what’s new?
2019: T21RS biennial meeting. Reduced Insulin Receptor Levels in Neuronal-Derived Exosomes Highlights Early Alterations of Brain Insulin Signaling in Down Syndrome.
2019: AD/PD biennial meeting. Loss of biliverdin reductase-a limits the oxidative stress-induced Akt-mediated inhibition of Gsk-3β: a novel molecular mechanism favoring Tau phosphorylation in early stage AD.
2018: EASD annual meeting. Biliverdin reductase-A mediates the beneficial effects of intranasal insulin administration in Alzheimer disease: a novel molecular mechanism.
2017: T21RS biennial meeting. The early onset of brain insulin resistance in Down Syndrome: a bridge toward the development of Alzheimer-like neuropathology.
2016: SfRBM annual meeting. Improvement of BVR-A activity ameliorates brain insulin resistance in Alzheimer disease following intranasal insulin administration.

Grants
2022 (PI): Jerome Lejeune Foundation, Project ID #2175 - GRT-2022B – € 80.000,00
2022 (PI): Banca d’Italia n. 1130944/22 del 22.07.2022 – € 52.000,00
2020 (PI): Alzheimer’s Association, Project ID 830355- $ 50.000,00 Dollars
2020 (PI): Jerome Lejeune Foundation, Project ID Cycle 2019b –#1887 – € 87.000,00
2020 (PI): Alzheimer’s Association, Project ID 2019-AARG-643091 - $ 150.000,00
2020 (I): Italian Ministry of Health, Project ID GR-2018-12366381 – € 442.000,00
2019 (PI): Sapienza University of Rome, Project ID RG11916B87F55459 – € 34.000,00
2017 (PI): Sapienza University of Rome, Project ID RM11715C77336E99 – € 12.000,00
2019 (I): Sapienza University of Rome, Project ID GA118164897F9CB1 - € 512.000,00
2018 (I): Sapienza University of Rome, Project ID RG1181642744DF59 – € 32.000,00
2017 (PI): Banca d’Italia n. 12868/17 del 5.1.2017 – 50.000,00 Euros
2015 (Co-PI): Italian MIUR, Project ID RBSI144MTL – € 170.000,00
2014 (PI): European Commission (FP7/2007-2013), Project ID 624341 – € 180.000,00

Patents
• Italian Patent n. 102021000012173 granted on June 2023: Compositions for use in the prevention and/or treatment of intellectual disability and neurodegenerative diseases in a subject with Down syndrome
• Patent Cooperation Treaty (PTC) request for the application ID 102021000012173 submitted on April 8th, 2022 (n. PCT/IB2022/053323) - ongoing

Research products

11573/1709575 - 2024 - Shaping down syndrome brain cognitive and molecular changes due to aging using adult animals from the Ts66Yah murine model

Lanzillotta, Chiara; Baniowska, Monika Rataj; Prestia, Francesca; Sette, Chiara; Nalesso, Valérie; Perluigi, Marzia; Barone, Eugenio; Duchon, Arnaud; Tramutola, Antonella; Herault, Yann; Di Domenico, Fabio - 01a Articolo in rivista

paper: NEUROBIOLOGY OF DISEASE (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. - - issn: 0969-9961 - wos: (0) - scopus: (0)

11573/1711799 - 2024 - Biliverdin Reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β

Lanzillotta, Chiara; Tramutola, Antonella; Lanzillotta, Simona; Greco, Viviana; Pagnotta, Sara; Sanchini, Caterina; Di Angelantonio, Silvia; Forte, Elena; Rinaldo, Serena; Paone, Alessio; Cutruzzolà, Francesca; Cimini, Flavia Agata; Barchetta, Ilaria; Cavallo, Maria Gisella; Urbani, Andrea; Butterfield, D Allan; Di Domenico, Fabio; Paul, Bindu D; Perluigi, Marzia; Duarte, Joao M N; Barone, Eugenio - 01a Articolo in rivista

paper: REDOX BIOLOGY (Amsterdam : Elsevier) pp. - - issn: 2213-2317 - wos: (0) - scopus: (0)

11573/1678614 - 2023 - Dynamic changes of BVRA protein levels occur in response to insulin: a pilot study in humans

Cimini, Flavia Agata; Tramutola, Antonella; Barchetta, Ilaria; Ceccarelli, Valentina; Gangitano, Elena; Lanzillotta, Simona; Lanzillotta, Chiara; Cavallo, Maria Gisella; Barone, Eugenio - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 7282- - issn: 1422-0067 - wos: WOS:000979287800001 (1) - scopus: 2-s2.0-85158058924 (1)

11573/1669305 - 2023 - A bioengineering strategy to control ADAM10 activity in living cells

Pastore, Francesco; Battistoni, Martina; Sollazzo, Raimondo; Renna, Pietro; Paciello, Fabiola; Li Puma, Domenica Donatella; Barone, Eugenio; Dagliyan, Onur; Ripoli, Cristian; Grassi, Claudio - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 917- - issn: 1422-0067 - wos: WOS:000917734900001 (1) - scopus: 2-s2.0-85146781855 (1)

11573/1700398 - 2023 - Engineering memory with an extrinsically disordered kinase

Ripoli, Cristian; Dagliyan, Onur; Renna, Pietro; Pastore, Francesco; Paciello, Fabiola; Sollazzo, Raimondo; Rinaudo, Marco; Battistoni, Martina; Martini, Sara; Tramutola, Antonella; Sattin, Andrea; Barone, Eugenio; Saneyoshi, Takeo; Fellin, Tommaso; Hayashi, Yasunori; Grassi, Claudio - 01a Articolo in rivista

paper: SCIENCE ADVANCES (Washington, DC : American Association for the Advancement of Science, 2015-) pp. - - issn: 2375-2548 - wos: WOS:001125318400007 (1) - scopus: 2-s2.0-85178498372 (1)

11573/1666748 - 2023 - Intranasal administration of KYCCSRK peptide rescues brain insulin signaling activation and reduces Alzheimer’s disease-like neuropathology in a mouse model for Down syndrome

Tramutola, Antonella; Lanzillotta, Simona; Aceto, Giuseppe; Pagnotta, Sara; Ruffolo, Gabriele; Cifelli, Pierangelo; Marini, Federico; Ripoli, Cristian; Palma, Eleonora; Grassi, Claudio; Di Domenico, Fabio; Perluigi, Marzia; Barone, Eugenio - 01a Articolo in rivista

paper: ANTIOXIDANTS (Basel: MDPI) pp. 111- - issn: 2076-3921 - wos: WOS:000916695100001 (11) - scopus: 2-s2.0-85146816588 (11)

11573/1612888 - 2022 - Brain insulin resistance: An early risk factor for Alzheimer's disease development in down syndrome

Barone, E. - 01a Articolo in rivista

paper: NEURAL REGENERATION RESEARCH (Shenyang : Publishing House of Neural Regeneration Research.) pp. 333-335 - issn: 1673-5374 - wos: WOS:000678125500026 (4) - scopus: 2-s2.0-85111052172 (4)

11573/1677861 - 2022 - Insulin Signaling Regulates Mitochondrial Bioenergetics in the Brain: Insight for the Development of Neurodegenerative Diseases

Barone, Eugenio - 01h Abstract in rivista

paper: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. - - issn: 0891-5849 - wos: WOS:000778588700009 (0) - scopus: (0)

11573/1642699 - 2022 - Role of biliverdin reductase A in the regulation of insulin signaling in metabolic and neurodegenerative diseases: An update

Cimini, Flavia Agata; Perluigi, Marzia; Barchetta, Ilaria; Cavallo, Maria Gisella; Barone, Eugenio - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 5574- - issn: 1422-0067 - wos: WOS:000803511200001 (4) - scopus: 2-s2.0-85130018794 (4)

11573/1634188 - 2022 - CAPE and its synthetic derivative VP961 restore BACH1/NRF2 axis in Down syndrome

Pagnotta, S.; Tramutola, A.; Barone, E.; Di Domenico, F.; Pittala, V.; Salerno, L.; Folgiero, V.; Caforio, M.; Locatelli, F.; Petrini, S.; Butterfield, D. A.; Perluigi, M. - 01a Articolo in rivista

paper: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 1-13 - issn: 0891-5849 - wos: WOS:000790734500001 (7) - scopus: 2-s2.0-85126271579 (11)

11573/1634186 - 2022 - Aberrant protein networks in Alzheimer disease

Perluigi, M.; Barone, E. - 01a Articolo in rivista

paper: NATURE REVIEWS. NEUROLOGY (London : Nature Publishing Group, 2009-) pp. 255-256 - issn: 1759-4758 - wos: WOS:000770211900001 (4) - scopus: 2-s2.0-85126736282 (5)

11573/1612865 - 2022 - Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal-derived extracellular vesicles

Perluigi, M.; Picca, A.; Montanari, E.; Calvani, R.; Marini, F.; Matassa, R.; Tramutola, A.; Villani, A.; Familiari, G.; Domenico, F. D.; Butterfield, D. A.; Oh, K. J.; Marzetti, E.; Valentini, D.; Barone, E. - 01a Articolo in rivista

paper: ALZHEIMER'S & DEMENTIA (New York : Elsevier, c2005-) pp. 1498-1510 - issn: 1552-5260 - wos: WOS:000721478900001 (16) - scopus: 2-s2.0-85119666649 (17)

11573/1634193 - 2022 - Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling

Vasavda, Chirag; Semenza, Evan R; Liew, Jason; Kothari, Ruchita; Dhindsa, Ryan S; Shanmukha, Shruthi; Lin, Anthony; Tokhunts, Robert; Ricco, Cristina; Snowman, Adele M; Albacarys, Lauren; Pastore, Francesco; Ripoli, Cristian; Grassi, Claudio; Barone, Eugenio; Kornberg, Michael D; Dong, Xinzhong; Paul, Bindu D; Snyder, Solomon H - 01a Articolo in rivista

paper: SCIENCE SIGNALING () pp. eabh3066- - issn: 1937-9145 - wos: WOS:000797366100001 (4) - scopus: 2-s2.0-85130002114 (5)

11573/1436701 - 2021 - Circulating dipeptidyl peptidase-4 is independently associated with the presence and severity of NAFLD/NASH in individuals with and without obesity and metabolic disease

Barchetta, I.; Ceccarelli, V.; Cimini, F. A.; Barone, E.; Sentinelli, F.; Coluzzi, M.; Chiappetta, C.; Bertoccini, L.; Tramutola, A.; Labbadia, G.; Di Cristofano, C.; Silecchia, G.; Leonetti, F.; Cavallo, M. G. - 01a Articolo in rivista

paper: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (Springer Milano: Editrice Kurtis Srl) pp. 979-988 - issn: 0391-4097 - wos: WOS:000564965600003 (26) - scopus: 2-s2.0-85089976237 (30)

11573/1610949 - 2021 - The interplay among oxidative stress, brain insulin resistance and AMPK dysfunction contribute to neurodegeneration in type 2 diabetes and Alzheimer disease

Barone, E.; Di Domenico, F.; Perluigi, M.; Butterfield, D. A. - 01a Articolo in rivista

paper: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 16-33 - issn: 0891-5849 - wos: WOS:000709495400002 (49) - scopus: 2-s2.0-85114802429 (60)

11573/1573343 - 2021 - Biliverdin reductase-A protein levels are reduced in type 2 diabetes and are associated with poor glycometabolic control

Cimini, F. A.; Barchetta, I.; Zuliani, I.; Pagnotta, S.; Bertoccini, L.; Dule, S.; Zampieri, M.; Reale, A.; Baroni, M. G.; Cavallo, M. G.; Barone, E. - 01a Articolo in rivista

paper: LIFE SCIENCES (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 119913- - issn: 0024-3205 - wos: WOS:000704012500010 (8) - scopus: 2-s2.0-85113811610 (8)

11573/1612872 - 2021 - Editorial: Brain insulin resistance in neurodevelopmental and neurodegenerative disorders: mind the gap!

Dierssen, M.; Barone, E. - 01m Editorial/Introduzione in rivista

paper: FRONTIERS IN NEUROSCIENCE (Lausanne (PO Box 110, 1015) : Frontiers Research Foundation, 2007-) pp. - - issn: 1662-4548 - wos: WOS:000688288400001 (4) - scopus: 2-s2.0-85113312472 (4)

11573/1612880 - 2021 - Building the future therapies for down syndrome: the third international conference of the T21 research society

Dierssen, M.; Herault, Y.; Helguera, P.; Martinez De Lagran, M.; Vazquez, A.; Christian, B.; Carmona-Iragui, M.; Wiseman, F.; Mobley, W.; Fisher, E. M. C.; Brault, V.; Esbensen, A.; Jacola, L. M.; Potier, M. C.; Hamlett, E. D.; Abbeduto, L.; Del Hoyo Soriano, L.; Busciglio, J.; Iulita, M. F.; Crispino, J.; Malinge, S.; Barone, E.; Perluigi, M.; Costanzo, F.; Delabar, J. M.; Bartesaghi, R.; Dekker, A. D.; De Deyn, P.; Fortea Ormaechea, J.; Shaw, P. A.; Haydar, T. F.; Sherman, S. L.; Strydom, A.; Bhattacharyya, A. - 01a Articolo in rivista

paper: MOLECULAR SYNDROMOLOGY (Basel : S. Karger AG, cop. 2010-) pp. 202-218 - issn: 1661-8769 - wos: WOS:000655133300001 (3) - scopus: 2-s2.0-85107461576 (4)

11573/1456191 - 2021 - Chronic perk induction promotes alzheimer-like neuropathology in down syndrome: Insights for therapeutic intervention

Lanzillotta, C.; Zuliani, I.; Tramutola, A.; Barone, E.; Blarzino, C.; Folgiero, V.; Caforio, M.; Valentini, D.; Villani, A.; Locatelli, F.; Butterfield, D. A.; Head, E.; Perluigi, M.; Abisambra, J. F.; Di Domenico, F. - 01a Articolo in rivista

paper: PROGRESS IN NEUROBIOLOGY (-Oxford:PERGAMON-ELSEVIER SCIENCE LTD, -Oxford; New York; Toronto; Rushcutters Bay; Braunschweig: Pergamon Press Vieweg & Sohn.) pp. 1-17 - issn: 0301-0082 - wos: WOS:000604785900004 (17) - scopus: 2-s2.0-85089501564 (22)

11573/1487153 - 2021 - Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: a harmful synergistic path in down syndrome

Lanzillotta, Chiara; Tramutola, Antonella; Di Giacomo, Graziella; Marini, Federico; Butterfield, D Allan; Di Domenico, Fabio; Perluigi, Marzia; Barone, Eugenio - 01a Articolo in rivista

paper: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 152-170 - issn: 0891-5849 - wos: WOS:000631946000004 (27) - scopus: 2-s2.0-85100251745 (28)

11573/1610951 - 2021 - mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder

Perluigi, M.; Di Domenico, F.; Barone, E.; Butterfield, D. A. - 01a Articolo in rivista

paper: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 382-396 - issn: 0891-5849 - wos: WOS:000653018200002 (55) - scopus: 2-s2.0-85105070584 (56)

11573/1612878 - 2021 - Valorization of tomato waste as a source of carotenoids

Trombino, S.; Cassano, R.; Procopio, D.; Di Gioia, M. L.; Barone, E. - 01a Articolo in rivista

paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 5062- - issn: 1420-3049 - wos: WOS:000689961900001 (33) - scopus: 2-s2.0-85113291510 (45)

11573/1532739 - 2021 - High-fat diet leads to reduced protein o-glcnacylation and mitochondrial defects promoting the development of Alzheimer’s disease signatures

Zuliani, I.; Lanzillotta, C.; Tramutola, A.; Barone, E.; Perluigi, M.; Rinaldo, S.; Paone, A.; Cutruzzola', F.; Bellanti, F.; Spinelli, M.; Natale, F.; Fusco, S.; Grassi, C.; Di Domenico, F. - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000638633700001 (16) - scopus: 2-s2.0-85103489586 (18)

11573/1474740 - 2021 - The dysregulation of OGT/OGA cycle mediates Tau and APP neuropathology in down syndrome

Zuliani, I.; Lanzillotta, C.; Tramutola, A.; Francioso, A.; Pagnotta, S.; Barone, E.; Perluigi, M.; Di Domenico, F. - 01a Articolo in rivista

paper: NEUROTHERAPEUTICS (Orlando, FL: Elsevier, c2007-) pp. 340-363 - issn: 1933-7213 - wos: WOS:000594792400002 (11) - scopus: 2-s2.0-85096999977 (10)

11573/1473716 - 2020 - Reduced biliverdin reductase-a expression in visceral adipose tissue is associated with adipocyte dysfunction and nafld in human obesity

Ceccarelli, V.; Barchetta, I.; Cimini, F. A.; Bertoccini, L.; Chiappetta, C.; Capoccia, D.; Carletti, R.; Di Cristofano, C.; Silecchia, G.; Fontana, M.; Leonetti, F.; Lenzi, A.; Baroni, M. G.; Barone, E.; Cavallo, M. G. - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 1-12 - issn: 1661-6596 - wos: WOS:000597990400001 (12) - scopus: 2-s2.0-85097038716 (11)

11573/1427027 - 2020 - Down syndrome Is a metabolic disease: altered Insulin signaling mediates peripheral and brain dysfunctions

Dierssen, Mara; Fructuoso, Marta; Martínez De Lagrán, María; Perluigi, Marzia; Barone, Eugenio - 01a Articolo in rivista

paper: FRONTIERS IN NEUROSCIENCE (Lausanne : EPFL : Frontiers Research Foundation, 2007-) pp. - - issn: 1662-453X - wos: WOS:000553850700001 (40) - scopus: 2-s2.0-85088421490 (46)

11573/1474752 - 2020 - Proteomics study of peripheral blood mononuclear cells in down syndrome children

Lanzillotta, C.; Greco, V.; Valentini, D.; Villani, A.; Folgiero, V.; Caforio, M.; Locatelli, F.; Pagnotta, S.; Barone, E.; Urbani, A.; Domenico, F. D.; Perluigi, M. - 01a Articolo in rivista

paper: ANTIOXIDANTS (Basel: MDPI) pp. 1-27 - issn: 2076-3921 - wos: WOS:000592837500001 (3) - scopus: 2-s2.0-85095984917 (4)

11573/1474757 - 2020 - BVR-A deficiency leads to autophagy impairment through the dysregulation of AMPK/mTOR axis in the brain—Implications for neurodegeneration

Lanzillotta, C.; Zuliani, I.; Vasavda, C.; Snyder, S.; Paul, B.; Perluigi, M.; Di Domenico, F.; Barone, E. - 01a Articolo in rivista

paper: ANTIOXIDANTS (Basel: MDPI) pp. 1-20 - issn: 2076-3921 - wos: WOS:000564629100001 (14) - scopus: 2-s2.0-85088956309 (18)

11573/1456172 - 2020 - The BACH1/Nrf2 axis in brain in down syndrome and transition to alzheimer disease-like neuropathology and dementia

Perluigi, Marzia; Tramutola, Antonella; Pagnotta, Sara; Barone, Eugenio; Allan Butterfield, D - 01a Articolo in rivista

paper: ANTIOXIDANTS (Basel: MDPI) pp. - - issn: 2076-3921 - wos: WOS:000581301200001 (22) - scopus: 2-s2.0-85090534759 (25)

11573/1419863 - 2020 - Heme oxygenase-1 in central nervous system malignancies

Sferrazzo, Giuseppe; Di Rosa, Michelino; Barone, Eugenio; Li Volti, Giovanni; Musso, Nicolò; Tibullo, Daniele; Barbagallo, Ignazio - 01a Articolo in rivista

paper: JOURNAL OF CLINICAL MEDICINE (MDPI Publishing, Basel, Switzerland) pp. 1562- - issn: 2077-0383 - wos: WOS:000540223800319 (22) - scopus: 2-s2.0-85090543199 (26)

11573/1381801 - 2020 - Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome

Tramutola, A.; Lanzillotta, C.; Di Domenico, F.; Head, E.; Butterfield, D. A.; Perluigi, M.; Barone, E. - 01a Articolo in rivista

11573/1336175 - 2019 - Greater circulating DPP4 activity is associated with impaired flow-mediated dilatation in adults with type 2 diabetes mellitus

Barchetta, I.; Ciccarelli, G.; Barone, E.; Cimini, F. A.; Ceccarelli, V.; Bertoccini, L.; Sentinelli, F.; Tramutola, A.; Del Ben, M.; Angelico, F.; Baroni, M. G.; Lenzi, A.; Cavallo, M. G. - 01a Articolo in rivista

paper: NMCD. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (-Amsterdam : Elsevier -Berlin : Springer -Milano: Medikal Press.) pp. 1087-1094 - issn: 0939-4753 - wos: WOS:000484832100012 (17) - scopus: 2-s2.0-85070712933 (16)

11573/1175653 - 2019 - Biliverdin reductase-A mediates the beneficial effects of intranasal insulin in Alzheimer disease

Barone, E; Tramutola, A; Triani, F; Calcagnini, S; Di Domenico, F; Ripoli, C; Gaetani, S; Grassi, C; Butterfield, Da; Cassano, T; Perluigi, M - 01a Articolo in rivista

paper: MOLECULAR NEUROBIOLOGY (Humana Press Incorporated:999 Riverview Drive, Suite 208:Totowa, NJ 07512:(973)256-1699, EMAIL: lglasner@humanapr.com, INTERNET: http://www.humanapress.com, Fax: (973)256-8341) pp. 2922-2943 - issn: 0893-7648 - wos: WOS:000465498200050 (56) - scopus: 2-s2.0-85051645596 (66)

11573/1244127 - 2019 - Reduced biliverdin reductase-a levels are associated with early alterations of insulin signaling in obesity

Cimini, Flavia Agata; Arena, Andrea; Barchetta, Ilaria; Tramutola, Antonella; Ceccarelli, Valentina; Lanzillotta, Chiara; Fontana, Mario; Bertoccini, Laura; Leonetti, Frida; Capoccia, Danila; Silecchia, Gianfranco; Di Cristofano, Claudio; Chiappetta, Caterina; Di Domenico, Fabio; Baroni, Marco Giorgio; Perluigi, Marzia; Cavallo, Maria Gisella; Barone, Eugenio - 01a Articolo in rivista

paper: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0925-4439 - wos: WOS:000468708200039 (27) - scopus: 2-s2.0-85062273097 (30)

11573/1273664 - 2019 - Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome

Di Domenico, Fabio; Tramutola, Antonella; Barone, Eugenio; Lanzillotta, Chiara; Defever, Olivia; Arena, Andrea; Zuliani, Ilaria; Foppoli, Cesira; Iavarone, Federica; Vincenzoni, Federica; Castagnola, Massimo; Butterfield, D Allan; Perluigi, Marzia - 01a Articolo in rivista

paper: REDOX BIOLOGY (Amsterdam : Elsevier) pp. 101162- - issn: 2213-2317 - wos: WOS:000498848200015 (45) - scopus: 2-s2.0-85062690014 (49)

11573/1244121 - 2019 - Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease

Sharma, Nidhi; Tramutola, Antonella; Lanzillotta, Chiara; Arena, Andrea; Blarzino, Carla; Cassano, Tommaso; Butterfield, D. Allan; Di Domenico, Fabio; Perluigi, Marzia; Barone, Eugenio - 01a Articolo in rivista

11573/1118370 - 2018 - Disturbance of redox homeostasis in down syndrome: role of iron dysmetabolism

Barone, Eugenio; Arena, Andrea; Head, Elizabeth; Butterfield, D. Allan; Perluigi, Marzia - 01a Articolo in rivista

paper: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 84-93 - issn: 0891-5849 - wos: WOS:000418889700010 (32) - scopus: 2-s2.0-85023755307 (40)

11573/1071360 - 2018 - Early and selective activation and subsequent alterations to the unfolded protein response in down syndrome mouse models

Lanzillotta, Chiara; Tramutola, Antonella; Meier, Shelby; Schmitt, Frederick; Barone, Eugenio; Perluigi, Marzia; Di Domenico, Fabio; Abisambra, Jose F - 01a Articolo in rivista

paper: JOURNAL OF ALZHEIMER'S DISEASE (Netherlands: IOS Press) pp. 347-359 - issn: 1387-2877 - wos: WOS:000424245200026 (16) - scopus: 2-s2.0-85047973196 (17)

11573/1175590 - 2018 - Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease

Tramutola, A; Sharma, N; Barone, E; Lanzillotta, C; Castellani, A; Iavarone, F; Vincenzoni, F; Castagnola, M; Butterfield, Da; Gaetani, S; Cassano, T; Perluigi, M; Di Domenico, F. - 01a Articolo in rivista

paper: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 3309-3321 - issn: 0925-4439 - wos: WOS:000445312000018 (28) - scopus: 2-s2.0-85050225026 (31)

11573/1175577 - 2018 - Poly-ubiquitin profile in Alzheimer disease brain

Tramutola, A; Triani, F; Di Domenico, F; Barone, E; Cai, J; Klein, Jb; Perluigi, M; Butterfield, Da. - 01a Articolo in rivista

11573/1178983 - 2018 - Protein nitration profile of CD3+ lymphocytes from Alzheimer disease patients: novel hints on immunosenescence and biomarker detection

Tramutola, Antonella; Abate, Giulia; Lanzillotta, Chiara; Triani, Francesca; Barone, Eugenio; Iavarone, Federica; Vincenzoni, Federica; Castagnola, Massimo; Marziano, Mariagrazia; Memo, Maurizio; Garrafa, Emirena; Butterfield, D Allan; Perluigi, Marzia; Di Domenico, Fabio; Uberti, Daniela - 01a Articolo in rivista

paper: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 430-439 - issn: 0891-5849 - wos: WOS:000450298400039 (19) - scopus: 2-s2.0-85055168925 (20)

11573/1199021 - 2018 - Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome

Tramutola, Antonella; Lanzillotta, Chiara; Barone, Eugenio; Arena, Andrea; Zuliani, Ilaria; Mosca, Luciana; Blarzino, Carla; Butterfield, D. Allan; Perluigi, Marzia; Di Domenico, Fabio - 01a Articolo in rivista

paper: TRANSLATIONAL NEURODEGENERATION (London : BioMed Central) pp. 1-28 - issn: 2047-9158 - wos: WOS:000449479100001 (67) - scopus: 2-s2.0-85056084092 (74)

11573/1175667 - 2018 - Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: implications for Alzheimer disease

Triani, F; Tramutola, A; Di Domenico, F; Sharma, N; Butterfield, Da; Head, E; Perluigi, M; Barone, E - 01a Articolo in rivista

paper: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 3181-3194 - issn: 0925-4439 - wos: WOS:000445312000007 (37) - scopus: 2-s2.0-85049953122 (38)

11573/947022 - 2017 - HNE-modified proteins in Down syndrome: involvement in development of Alzheimer disease neuropathology

Barone, Eugenio; Head, Elizabeth; Butterfield, D. Allan; Perluigi, Marzia - 01a Articolo in rivista

paper: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 262-269 - issn: 0891-5849 - wos: WOS:000406049900023 (35) - scopus: 2-s2.0-85006823445 (38)

11573/1344404 - 2017 - Behavioural and neuropathological effects of intranasal insulin treatment in a triple-transgenic mouse model of Alzheimer's disease (3xTg-AD)

Calcagnini, Silvio; Barone, Eugenio; Lavecchia, Angelo Michele; Lancioni, Martina; Meconi, Annachiara; Perluigi, Marzia; Cassano, Tommaso - 04f Poster

conference: 38° Congresso Nazionale della Società Italiana di Farmacologia "Farmaci, Salute e Qualità della vita" (Rimini)

book: Behavioural and neuropathological effects of intranasal insulin treatment in a triple-transgenic mouse model of Alzheimer's disease (3xTg-AD) - ()

11573/935434 - 2017 - The triangle of death in Alzheimer's disease brain: the aberrant cross-talk among energy metabolism, mammalian target of rapamycin signaling, and protein homeostasis revealed by redox proteomics

Di Domenico, Fabio; Barone, Eugenio; Perluigi, Marzia; Butterfield, D. Allan - 01a Articolo in rivista

paper: ANTIOXIDANTS & REDOX SIGNALING (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. - - issn: 1523-0864 - wos: WOS:000395554300002 (86) - scopus: 2-s2.0-85014561567 (94)

11573/935443 - 2017 - Modulation of GLP-1 signaling as a novel therapeutic approach in the treatment of Alzheimer’s disease pathology

Tramutola, Antonella; Arena, Andrea; Cini, Chiara; Butterfield, D. Allan; Barone, Eugenio - 01a Articolo in rivista

paper: EXPERT REVIEW OF NEUROTHERAPEUTICS (-London, United Kingdom: Expert Reviews Ltd -London, United Kingdom: Future Drugs Limited) pp. 59-75 - issn: 1473-7175 - wos: WOS:000390241300007 (56) - scopus: 2-s2.0-85004024046 (22)

11573/935436 - 2017 - Polyubiquitinylation profile in down syndrome brain before and after the development of Alzheimer neuropathology

Tramutola, Antonella; Di Domenico, Fabio; Barone, Eugenio; Arena, Andrea; Giorgi, Alessandra; Di Francesco, Laura; Schinina', Maria Eugenia; Coccia, Raffaella; Head, Elizabeth; Butterfield, D. Allan; Perluigi, Marzia - 01a Articolo in rivista

paper: ANTIOXIDANTS & REDOX SIGNALING (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 280-298 - issn: 1523-0864 - wos: WOS:000394334400002 (32) - scopus: 2-s2.0-85013434336 (36)

11573/935449 - 2016 - Editorial: Oxidative stress and Alzheimer disease: where do we stand?

Barone, Eugenio - 01a Articolo in rivista

paper: CURRENT ALZHEIMER RESEARCH (BENTHAM SCIENCE PUBL LTD,) pp. 108-111 - issn: 1567-2050 - wos: WOS:000372101800001 (11) - scopus: 2-s2.0-84959377101 (10)

11573/846243 - 2016 - Impairment of biliverdin reductase-a promotes brain insulin resistance in Alzheimer disease: a new paradigm

Barone, Eugenio; Di Domenico, Fabio; Cassano, Tommaso; Arena, Andrea; Tramutola, Antonella; Lavecchia, Michele Angelo; Coccia, Raffaella; Butterfield, D. Allan; Perluigi, Marzia - 01a Articolo in rivista

paper: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 127-142 - issn: 0891-5849 - wos: WOS:000370181400012 (88) - scopus: 2-s2.0-84950335909 (91)

11573/947023 - 2016 - Aberrant protein phosphorylation in Alzheimer disease brain disturbs pro-survival and cell death pathways

Perluigi, Marzia; Barone, Eugenio; Di Domenico, Fabio; Butterfield, D. A. - 01a Articolo in rivista

paper: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1871-1882 - issn: 0925-4439 - wos: WOS:000382413300003 (59) - scopus: 2-s2.0-84979620769 (63)

11573/871573 - 2016 - It is all about (U)biquitin: role of altered ubiquitin-proteasome system and UCHL1 in Alzheimer disease

Tramutola, Antonella; Di Domenico, Fabio; Barone, Eugenio; Perluigi, Marzia; Butterfield, David Allan - 01a Articolo in rivista

paper: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (London: Hindawi AUSTIN, USA, TX: LANDES BIOSCIENCE) pp. - - issn: 1942-0900 - wos: WOS:000372640600001 (78) - scopus: 2-s2.0-84961344015 (79)

11573/840612 - 2016 - Increased mammalian target of rapamycin signaling contributes to the accumulation of protein oxidative damage in a mouse model of down's syndrome

Tramutola, Antonella; Lanzillotta, Chiara; Arena, Andrea; Barone, Eugenio; Perluigi, Marzia; Di Domenico, Fabio - 01a Articolo in rivista

paper: NEURODEGENERATIVE DISEASES (Basel [etc.]: S. Karger 2004-) pp. 62-68 - issn: 1660-2854 - wos: WOS:000369778000010 (33) - scopus: 2-s2.0-84958063630 (34)

11573/867882 - 2016 - Activation of p53 in down syndrome and in the ts65dn mouse brain is associated with a pro-apoptotic phenotype

Tramutola, Antonella; Pupo, Gilda; Di Domenico, Fabio; Barone, Eugenio; Arena, Andrea; Lanzillotta, Chiara; Broekaart, Diede; Blarzino, Carla; Head, Elizabeth; Butterfield, D. Allan; Perluigi, Marzia - 01a Articolo in rivista

paper: JOURNAL OF ALZHEIMER'S DISEASE (Netherlands: IOS Press) pp. 359-71-371 - issn: 1387-2877 - wos: WOS:000375008500030 (25) - scopus: 2-s2.0-84973143959 (30)

11573/784073 - 2015 - Insulin resistance in Alzheimer disease: Is heme oxygenase-1 an Achille's heel?

Barone, Eugenio; A., Butterfield - 01a Articolo in rivista

11573/796560 - 2015 - Basal brain oxidative and nitrative stress levels are finely regulated by the interplay between superoxide dismutase 2 and p53

Barone, Eugenio; Cenini, Giovanna; Di Domenico, Fabio; Noel, Teresa; Wang, Chi; Perluigi, Marzia; Daret K., S. T. Clair; Butterfield, D. Allan - 01a Articolo in rivista

paper: JOURNAL OF NEUROSCIENCE RESEARCH (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 1728-39-1739 - issn: 0360-4012 - wos: WOS:000362831800011 (17) - scopus: 2-s2.0-84941994540 (18)

11573/670428 - 2015 - Strategy to reduce free radical species in Alzheimer's disease: an update of selected antioxidants

Di Domenico, Fabio; Barone, Eugenio; Perluigi, Marzia; Butterfield, Da - 01a Articolo in rivista

paper: EXPERT REVIEW OF NEUROTHERAPEUTICS (-London, United Kingdom: Expert Reviews Ltd -London, United Kingdom: Future Drugs Limited) pp. - - issn: 1473-7175 - wos: WOS:000347802800004 (77) - scopus: 2-s2.0-84920840714 (90)

11573/670416 - 2015 - Bach1 overexpression in down syndrome correlates with the alteration of the ho-1/bvr-a system: insights for transition to Alzheimer's disease

Di Domenico, Fabio; Pupo, Gilda; Mancuso, C; Barone, Eugenio; Paolini, F; Arena, Andrea; Blarzino, Carla; Schmitt, Fa; Head, E; Butterfield, Da; Perluigi, Marzia - 01a Articolo in rivista

paper: JOURNAL OF ALZHEIMER'S DISEASE (Netherlands: IOS Press) pp. - - issn: 1387-2877 - wos: WOS:000350001000007 (49) - scopus: 2-s2.0-84923270517 (52)

11573/784064 - 2014 - The Janus face of the heme oxygenase/biliverdin reductase system in Alzheimer disease: It's time for reconciliation

Barone, Eugenio; Di Domenico, Fabio; C., Mancuso; D., Butterfield - 01a Articolo in rivista

11573/556360 - 2014 - Statins more than cholesterol lowering agents in Alzheimer disease: Their pleiotropic functions as potential therapeutic targets.

Barone, Eugenio; Di Domenico, Fabio; D. A., Butterfield - 01a Articolo in rivista

paper: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited -London ; New York : Pergamon Press, 1958-) pp. 605-616 - issn: 0006-2952 - wos: WOS:000334977400019 (78) - scopus: 2-s2.0-84897954198 (84)

11573/784069 - 2014 - Inactivation of brain Cofilin-1 by age, Alzheimer's disease and γ-secretase

Barone, Eugenio; S., Mosser; P., Fraering - 01a Articolo in rivista

paper: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 2500-2509 - issn: 0925-4439 - wos: WOS:000347590700016 (50) - scopus: 2-s2.0-84918537379 (48)

11573/670432 - 2014 - Elevated risk of type 2 diabetes for development of Alzheimer disease: a key role for oxidative stress in brain

Butterfield, Da; Di Domenico, Fabio; Barone, Eugenio - 01a Articolo in rivista

paper: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1693-1706 - issn: 0925-4439 - wos: WOS:000340975400041 (277) - scopus: 2-s2.0-84904113244 (289)

11573/556926 - 2014 - Neuropathological role of pi3k/akt/mtor axis in Down syndrome brain

Perluigi, Marzia; Pupo, Gilda; Tramutola, Antonella; Cini, Chiara; Coccia, Raffaella; Barone, Eugenio; E., Head; D. A., Butterfield; Di Domenico, Fabio - 01a Articolo in rivista

paper: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1144-1153 - issn: 0925-4439 - wos: WOS:000336698400027 (120) - scopus: 2-s2.0-84899787783 (127)

11573/670470 - 2013 - Biliverdin Reductase-A correlates with inducible nitric oxide synthasein in atorvastatin treated aged canine brain.

Di Domenico, Fabio; Perluigi, Marzia; Barone, Eugenio - 01a Articolo in rivista

paper: NEURAL REGENERATION RESEARCH (Shenyang : Publishing House of Neural Regeneration Research.) pp. 1925-1937 - issn: 1673-5374 - wos: WOS:000325239400008 (0) - scopus: 2-s2.0-84886903907 (13)

11573/784058 - 2013 - Trans-ferulic acid-based solid lipid nanoparticles and their antioxidant effect in rat brain microsomes

S., Trombino; R., Cassano; T., Ferrarelli; Barone, Eugenio; N., Picci; C., Mancuso - 01a Articolo in rivista

paper: COLLOIDS AND SURFACES. B, BIOINTERFACES (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 273-279 - issn: 0927-7765 - wos: WOS:000320413300039 (82) - scopus: 2-s2.0-84877806241 (96)

11573/784054 - 2012 - Lack of p53 Affects the Expression of Several Brain Mitochondrial Proteins: Insights from Proteomics into Important Pathways Regulated by p53

A., Fiorini; R., Sultana; Barone, Eugenio; G., Cenini; Perluigi, Marzia; C., Mancuso; J., Cai; J., Klein; D. S., Clair; D., Butterfield - 01a Articolo in rivista

paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. - - issn: 1932-6203 - wos: WOS:000311885800026 (14) - scopus: 2-s2.0-84870267018 (14)

11573/463583 - 2012 - Biliverdin reductase-A: a novel drug target for atorvastatin in a dog pre-clinical model of Alzheimer disease

Barone, Eugenio; C., Mancuso; Di Domenico, Fabio; R., Sultana; M. P., Murphy; E., Head; D. A., Butterfield - 01a Articolo in rivista

paper: JOURNAL OF NEUROCHEMISTRY (Editore attuale:BLACKWELL PUBLISHING LTD, 9600 GARSINGTON RD, OXFORD, ENGLAND, OXON, OX4 2DG Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320) pp. 135-146 - issn: 0022-3042 - wos: WOS:000298060500014 (62) - scopus: 2-s2.0-83755221773 (65)

11573/460535 - 2012 - Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment

Barone, Eugenio; Di Domenico, Fabio; Rukhsana, Sultana; Coccia, Raffaella; Cesare, Mancuso; Perluigi, Marzia; D., Allan Butterfield - 01a Articolo in rivista

paper: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 2292-2301 - issn: 0891-5849 - wos: WOS:000305857300015 (103) - scopus: 2-s2.0-84861601576 (107)

11573/441034 - 2012 - Lack of p53 Decreases Basal Oxidative Stress Levels in the Brain Through Upregulation of Thioredoxin-1, Biliverdin Reductase-A, Manganese Superoxide Dismutase, and Nuclear Factor Kappa-B

Barone, Eugenio; Giovanna, Cenini; Rukhsana, Sultana; Di Domenico, Fabio; Fiorini, Ada; Perluigi, Marzia; Teresa, Noel; Chi, Wang; Cesare, Mancuso; D. K., St; D., Allan Butterfield - 01a Articolo in rivista

paper: ANTIOXIDANTS & REDOX SIGNALING (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 1407-1420 - issn: 1523-0864 - wos: WOS:000303047100004 (27) - scopus: 2-s2.0-84860206827 (27)

11573/784047 - 2012 - Natural substances and Alzheimer's disease: From preclinical studies to evidence based medicine

C., Mancuso; R., Siciliano; Barone, Eugenio; P., Preziosi - 01a Articolo in rivista

paper: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 616-624 - issn: 0925-4439 - wos: WOS:000302486400002 (72) - scopus: 2-s2.0-84858155062 (83)

11573/1612891 - 2012 - Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome

Cenini, G.; Dowling, A. L. S.; Beckett, T. L.; Barone, E.; Mancuso, C.; Murphy, M. P.; Levine, H.; Lott, I. T.; Schmitt, F. A.; Butterfield, D. A.; Head, E. - 01a Articolo in rivista

paper: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 130-138 - issn: 0925-4439 - wos: WOS:000299986600004 (86) - scopus: 2-s2.0-83055187877 (100)

11573/460488 - 2012 - Inhibition of lipid peroxidation and protein oxidation by endogenous and exogenous antioxidants in rat brain microsomes in vitro

Cesare, Mancuso; Barone, Eugenio; Pina, Guido; Fiorella, Miceli; Di Domenico, Fabio; Perluigi, Marzia; Rosaria, Santangelo; Paolo, Preziosi - 01a Articolo in rivista

paper: NEUROSCIENCE LETTERS (Limerick Ireland: Elsevier Science Ireland Limited) pp. 101-105 - issn: 0304-3940 - wos: WOS:000305713200007 (70) - scopus: 2-s2.0-84861682913 (73)

11573/784051 - 2012 - Atorvastatin treatment in a dog preclinical model of Alzheimer's disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain

D., Butterfield; Barone, Eugenio; Di Domenico, Fabio; G., Cenini; R., Sultana; M., Murphy; C., Mancuso; E., Head - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. 981-987 - issn: 1461-1457 - wos: WOS:000307187400011 (62) - scopus: 2-s2.0-84864349775 (65)

11573/468362 - 2012 - HO-1/BVR-A system analysis in plasma from probable Alzheimer's disease and mild cognitive impairment subjects: A potential biochemical marker for the prediction of the disease

Di Domenico, Fabio; Barone, Eugenio; C., Mancuso; Perluigi, Marzia; Cocciolo, Annalisa; P., Mecocci; D. A., Butterfield; Coccia, Raffaella - 01a Articolo in rivista

paper: JOURNAL OF ALZHEIMER'S DISEASE (Netherlands: IOS Press) pp. 277-289 - issn: 1387-2877 - wos: WOS:000309977800004 (44) - scopus: 2-s2.0-84867489401 (45)

11573/441036 - 2012 - Sex differences in brain proteomes of neuron-specific STAT3-null mice after cerebral ischemia/reperfusion.

Di Domenico, Fabio; G., Casalena; J., Jia; R., Sultana; Barone, Eugenio; J., Cai; W. M., Pierce; Cini, Chiara; C., Mancuso; Perluigi, Marzia; C. M., Davis; N. J., Alkayed; A. D., Butterfield - 01a Articolo in rivista

paper: JOURNAL OF NEUROCHEMISTRY (Editore attuale:BLACKWELL PUBLISHING LTD, 9600 GARSINGTON RD, OXFORD, ENGLAND, OXON, OX4 2DG Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320) pp. 680-692 - issn: 0022-3042 - wos: WOS:000302721400018 (29) - scopus: 2-s2.0-84859747516 (27)

11573/441035 - 2012 - Redox Proteomics Analyses of the Influence of Co-Expression of Wild-Type or Mutated LRRK2 and Tau on C. elegans Protein Expression and Oxidative Modification: Relevance to Parkinson Disease

Di Domenico, Fabio; Rukhsana, Sultana; Andrew, Ferree; Katelyn, Smith; Barone, Eugenio; Perluigi, Marzia; Coccia, Raffaella; William, Pierce; Jian, Cai; Cesare, Mancuso; Rachel, Squillace; Manfred, Wiengele; Isabella Dalle, Donne; Benjamin, Wolozin; D., Allan Butterfield - 01a Articolo in rivista

paper: ANTIOXIDANTS & REDOX SIGNALING (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 1490-1506 - issn: 1523-0864 - wos: WOS:000309509200002 (41) - scopus: 2-s2.0-84866663422 (41)

11573/375942 - 2011 - Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment

Barone, Eugenio; Di Domenico, Fabio; Cenini, G; Sultana, R; Cini, Chiara; Preziosi, P; Perluigi, Marzia; Mancuso, C; Butterfield, Da - 01a Articolo in rivista

paper: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 480-487 - issn: 0925-4439 - wos: WOS:000288301500007 (84) - scopus: 2-s2.0-79551569963 (84)

11573/366160 - 2011 - Oxidative and Nitrosative Modifications of Biliverdin Reductase-A in the Brain of Subjects with Alzheimer’s Disease and Amnestic Mild Cognitive Impairment

Barone, Eugenio; Di Domenico, Fabio; Cenini, G; Sultana, R; Coccia, Raffaella; Preziosi, P; Perluigi, Marzia; Mancuso, C; Butterfield, Da - 01a Articolo in rivista

paper: JOURNAL OF ALZHEIMER'S DISEASE (Netherlands: IOS Press) pp. 623-633 - issn: 1387-2877 - wos: WOS:000293595400005 (78) - scopus: 2-s2.0-80052829260 (83)

11573/354281 - 2011 - Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: A novel mechanism of action

Barone, Eugenio; Giovanna, Cenini; Di Domenico, Fabio; Sarah, Martin; Rukhsana, Sultana; Cesare, Mancuso; Michael Paul, Murphy; Elizabeth, Head; D., Allan Butterfield - 01a Articolo in rivista

paper: PHARMACOLOGICAL RESEARCH (Attuale:ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 24-28 OVAL RD, LONDON, ENGLAND, NW1 7DX Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 162-180 - issn: 1043-6618 - wos: WOS:000288041400003 (80) - scopus: 2-s2.0-79751532850 (80)

11573/784076 - 2011 - Curcumin and alzheimer disease: this marriage is not to be performed

C., Mancuso; R., Siciliano; Barone, Eugenio - 01a Articolo in rivista

paper: JOURNAL OF BIOLOGICAL CHEMISTRY (Bethesda, Md. : American Society for Biochemistry and Molecular Biology) pp. - - issn: 1083-351X - wos: WOS:000286191500004 (37) - scopus: 2-s2.0-78751487371 (42)

11573/784082 - 2011 - Cholesterol-independent neuroprotective and neurotoxic activities of statins: Perspectives for statin use in Alzheimer disease and other age-related neurodegenerative disorders

D., Butterfield; Barone, Eugenio; C., Mancuso - 01a Articolo in rivista

paper: PHARMACOLOGICAL RESEARCH (Attuale:ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 24-28 OVAL RD, LONDON, ENGLAND, NW1 7DX Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 180-186 - issn: 1043-6618 - wos: WOS:000293120100003 (73) - scopus: 2-s2.0-79959953827 (74)

11573/354278 - 2011 - Quantitative proteomics analysis of phosphorylated proteins in the hippocampus of Alzheimer's disease subjects

Di Domenico, Fabio; Rukhsana, Sultana; Barone, Eugenio; Perluigi, Marzia; Cini, Chiara; Cesare, Mancuso; Jian, Cai; William M., Pierce; D., Allan Butterfield - 01a Articolo in rivista

paper: JOURNAL OF PROTEOMICS () pp. 1091-1103 - issn: 1874-3919 - wos: WOS:000292440400019 (80) - scopus: 2-s2.0-79957644804 (85)

11573/784081 - 2011 - Pharmacologists and Alzheimer disease therapy: To boldly go where no scientist has gone before

Mancuso, Cesare; Siciliano, Raffaella; Barone, Eugenio; Butterfield, David Allan; Preziosi, Paolo - 01a Articolo in rivista

paper: EXPERT OPINION ON INVESTIGATIONAL DRUGS (-London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 1243-1261 - issn: 1354-3784 - wos: WOS:000293897900006 (48) - scopus: 2-s2.0-80051710827 (51)

11573/784080 - 2011 - Coenzyme Q10 and cognition in atorvastatin treated dogs

S., Martin; G., Cenini; Barone, Eugenio; A., Dowling; C., Mancuso; D., Butterfield; M., Murphy; E., Head - 01a Articolo in rivista

paper: NEUROSCIENCE LETTERS (Limerick Ireland: Elsevier Science Ireland Limited) pp. 92-95 - issn: 0304-3940 - wos: WOS:000294317600007 (13) - scopus: 2-s2.0-79961129553 (15)

11573/784084 - 2011 - Experimental research on nitric oxide and the therapy of alzheimer disease: A challenging bridge

Siciliano, Raffaella; Barone, Eugenio; Calabrese, Vittorio; Rispoli, Vincenzo; Butterfield, D. Allan; Mancuso, Cesare - 01a Articolo in rivista

paper: CNS & NEUROLOGICAL DISORDERS. DRUG TARGETS (Sharjah : Bentham Science Publishers) pp. 766-776 - issn: 1996-3181 - wos: WOS:000298248100003 (12) - scopus: 2-s2.0-81155126167 (15)

11573/935448 - 2010 - In vivo protective effect of ferulic acid against noise-induced hearing loss in the guinea-pig

Fetoni, A. R.; Mancuso, C; Eramo, S. L. M.; Ralli, Massimo; Piacentini, R.; Barone, Eugenio; Paludetti, G.; Troiani, D. - 01a Articolo in rivista

paper: NEUROSCIENCE (Oxford: Elsevier Ltd. Oxford; New York: Pergamon Press) pp. 1575-1588 - issn: 0306-4522 - wos: WOS:000281050600010 (97) - scopus: 2-s2.0-77955413595 (117)

11573/784074 - 2010 - Synthesis, characterization, and anti-inflammatory activity of diclofenac-bound cotton fibers

R., Cassano; S., Trombino; T., Ferrarelli; Barone, Eugenio; V., Arena; C., Mancuso; N., Picci - 01a Articolo in rivista

11573/784072 - 2010 - Heme oxygenase-derived carbon monoxide modulates gonadotropin-releasing hormone release in immortalized hypothalamic neurons

S., Errico; R., Shohreh; Barone, Eugenio; A., Pusateri; N., Mores; C., Mancuso - 01a Articolo in rivista

paper: NEUROSCIENCE LETTERS (Limerick Ireland: Elsevier Science Ireland Limited) pp. 175-178 - issn: 0304-3940 - wos: WOS:000275779800011 (17) - scopus: 2-s2.0-76749108396 (17)

11573/784093 - 2009 - Characterization of the S-denitrosylating activity of bilirubin.

Barone, Eugenio; Trombino, S; Cassano, R; Sgambato, A; De Paola, B; Di Stasio, E; Picci, N; Preziosi, P; Mancuso, C. - 01a Articolo in rivista

paper: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (Bucharest : Foundation for Cellular and Molecular Medicine.) pp. - - issn: 1582-1838 - wos: WOS:000272190800067 (65) - scopus: 2-s2.0-70349460085 (67)

11573/784059 - 2009 - Ferulic acid and its therapeutic potential as a hormetin for age-related diseases

Barone, Eugenio; V., Calabrese; C., Mancuso - 01a Articolo in rivista

paper: BIOGERONTOLOGY (London ; Dordrecht ; Boston : Kluwer Academic Publishers) pp. 97-108 - issn: 1389-5729 - wos: WOS:000263785400001 (226) - scopus: 2-s2.0-61849147931 (261)

11573/784063 - 2009 - Curcumin in clinical practice: myth or reality?

C., Mancuso; Barone, Eugenio - 01a Articolo in rivista

paper: TRENDS IN PHARMACOLOGICAL SCIENCES (Elsevier Trends Journals:An Imprint of Elsevier Science Limited, The Boulevard, Langford Lane, Kidlington, Oxford 0X5 1GB United Kingdom:011 44 1865 843000, 011 44 1865 843699, Fax: 011 44 1865 843010) pp. 333-334 - issn: 0165-6147 - wos: WOS:000268378700002 (58) - scopus: 2-s2.0-67649407501 (69)

11573/784067 - 2009 - Therapeutic use of tea derivatives: All that glitters is not gold

C., Mancuso; Barone, Eugenio - 01a Articolo in rivista

paper: BLOOD (New York: Elsevier Inc. [Washington DC etc.]: American Society of Hematology) pp. 2359-2360 - issn: 0006-4971 - wos: WOS:000269698400027 (8) - scopus: 2-s2.0-70349579538 (9)

11573/784070 - 2009 - The heme oxygenase/biliverdin reductase pathway in drug research and development

C., Mancuso; Barone, Eugenio - 01a Articolo in rivista

paper: CURRENT DRUG METABOLISM (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 579-594 - issn: 1389-2002 - wos: WOS:000271380200004 (94) - scopus: 2-s2.0-70450137050 (95)

11573/784094 - 2009 - Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases.

Calabrese, V; Cornelius, C; Mancuso, C; Barone, Eugenio; Calafato, S; Bates, T; Rizzarelli, E; Kostova, At - 01a Articolo in rivista

paper: FRONTIERS IN BIOSCIENCE () pp. - - issn: 1093-4715 - wos: WOS:000262352400023 (109) - scopus: 2-s2.0-63849154150 (115)

11573/784056 - 2008 - Heme oxygenase expression and activity in immortalized hypothalamic neurons GT1-7

N., Mores; S., Errico; A., Pusateri; Barone, Eugenio; C., Mancuso - 01a Articolo in rivista

paper: NEUROSCIENCE LETTERS (Limerick Ireland: Elsevier Science Ireland Limited) pp. 106-108 - issn: 0304-3940 - wos: WOS:000260066900023 (2) - scopus: 2-s2.0-50849103655 (2)

11573/784055 - 2008 - The protective role of carotenoids against 7-keto-cholesterol formation in solution

P., Palozza; Barone, Eugenio; C., Mancuso; N., Picci - 01a Articolo in rivista

paper: MOLECULAR AND CELLULAR BIOCHEMISTRY (Kluwer Academic Publishers / Massachusetts:PO Box 358, Accord Station:Hingham, MA 02018:(617)871-6600) pp. 61-68 - issn: 0300-8177 - wos: WOS:000252638200007 (37) - scopus: 2-s2.0-38649097588 (41)