ENRICO DE SMAELE

Professore ordinario

email: enrico.desmaele@uniroma1.it
telefono: 0774/85868-06/4958637




Produzione scientifica

11573/1730116 - 2024 - SMURF1 and SMURF2 directly target GLI1 for ubiquitination and proteasome-dependent degradation
Bordin, F.; Terriaca, G.; Apostolico, A.; Di Fiore, A.; Taj Mir, F.; Bellardinelli, S.; Bufalieri, F.; Bordone, R.; Bellardinilli, F.; Giannini, G.; Canettieri, G.; Di Marcotullio, L.; Ferretti, E.; Moretti, M.; De Smaele, E. - 01a Articolo in rivista
rivista: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. - - issn: 2058-7716 - wos: (0) - scopus: 2-s2.0-85212438098 (0)

11573/1721584 - 2024 - MYC upstream region orchestrates resistance to PI3K inhibitors in cancer cells through FOXO3a-mediated autophagic adaptation
Bordone, Rosa; Ivy, Devon Michael; D'amico, Rodrigo; Barba, Martina; Gaggianesi, Miriam; Di Pastena, Fiorella; Cesaro, Bianca; Bufalieri, Francesca; Balzerano, Alessio; De Smaele, Enrico; Giannini, Giuseppe; Di Marcotullio, Lucia; Fatica, Alessandro; Stassi, Giorgio; Di Magno, Laura; Coni, Sonia; Canettieri, Gianluca - 01a Articolo in rivista
rivista: ONCOGENE (Basingstoke: Nature Publishing Group.) pp. 3349-3365 - issn: 1476-5594 - wos: WOS:001316838400001 (0) - scopus: 2-s2.0-85204520129 (0)

11573/1692856 - 2024 - SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma
Lospinoso Severini, Ludovica; Loricchio, Elena; Navacci, Shirin; Basili, Irene; Alfonsi, Romina; Bernardi, Flavia; Moretti, Marta; Conenna, Marilisa; Cucinotta, Antonino; Coni, Sonia; Petroni, Marialaura; De Smaele, Enrico; Giannini, Giuseppe; Maroder, Marella; Canettieri, Gianluca; Mastronuzzi, Angela; Guardavaccaro, Daniele; Ayrault, Olivier; Infante, Paola; Bufalieri, Francesca; Di Marcotullio, Lucia - 01a Articolo in rivista
rivista: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. - - issn: 1350-9047 - wos: WOS:001119029000002 (3) - scopus: 2-s2.0-85178929821 (3)

11573/1686292 - 2023 - β-arrestin1-E2F1-ac axis regulates physiological apoptosis and cell cycle exit in cellular models of early postnatal cerebellum
Abballe, Luana; Alfano, Vincenzo; Antonacci, Celeste; Giuseppina Cefalo, Maria; Cacchione, Antonella; Del Baldo, Giada; Pezzullo, Marco; Po, Agnese; Moretti, Marta; Mastronuzzi, Angela; De Smaele, Enrico; Ferretti, Elisabetta; Locatelli, Franco; Miele, Evelina - 01a Articolo in rivista
rivista: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-634X - wos: WOS:000947908400001 (0) - scopus: 2-s2.0-85150019785 (0)

11573/1691548 - 2023 - The inhibition of IRE1alpha/XBP1 axis prevents EBV-driven lymphomagenesis in NSG mice
Arena, Andrea; Romeo, Maria Anele; Po, Agnese; Benedetti, Rossella; Gilardini Montani, Maria Saveria; Gonnella, Roberta; Santarelli, Roberta; Gaeta, Aurelia; De Smaele, Enrico; Cirone, Mara - 01a Articolo in rivista
rivista: MICROBIOLOGY SPECTRUM (Washington, DC : ASM Press, 2014-) pp. 1-6 - issn: 2165-0497 - wos: WOS:001095474200001 (0) - scopus: 2-s2.0-85180012834 (0)

11573/1677425 - 2023 - Hedgehog-GLI and notch pathways sustain chemoresistance and invasiveness in colorectal cancer and their Inhibition restores chemotherapy efficacy
Citarella, Anna; Catanzaro, Giuseppina; Besharat, Zein Mersini; Trocchianesi, Sofia; Barbagallo, Federica; Gosti, Giorgio; Leonetti, Marco; Di Fiore, Annamaria; Coppola, Lucia; Autilio, Tanja Milena; Spinello, Zaira; Vacca, Alessandra; De Smaele, Enrico; Venneri, Mary Anna; Ferretti, Elisabetta; Masuelli, Laura; Po, Agnese - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. 1-16 - issn: 2072-6694 - wos: WOS:000947305400001 (12) - scopus: 2-s2.0-85149860378 (12)

11573/1674490 - 2023 - Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation
Coni, Sonia; Bordone, Rosa; Ivy, Devon Michael; Yurtsever, Zuleyha Nihan; Di Magno, Laura; D'amico, Rodrigo; Cesaro, Bianca; Fatica, Alessandro; Belardinilli, Francesca; Bufalieri, Francesca; Maroder, Marella; De Smaele, Enrico; Di Marcotullio, Lucia; Giannini, Giuseppe; Agostinelli, Enzo; Canettieri, Gianluca - 01a Articolo in rivista
rivista: CANCER LETTERS (Elsevier Science Ireland Limited:PO Box 85, Limerick Ireland:011 353 61 709600, 011 353 61 61944, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 353 61 709114) pp. - - issn: 0304-3835 - wos: WOS:000955037000001 (15) - scopus: 2-s2.0-85150380153 (16)

11573/1687401 - 2023 - KCTD1 is a new modulator of the KCASH family of Hedgehog suppressors
Di Fiore, A; Bellardinelli, S; Pirone, L; Russo, R; Angrisani, A; Terriaca, G; Bowen, M; Bordin, F; Besharat, Z M; Canettieri, G; Fabretti, F; Di Gaetano, S; Di Marcotullio, L; Pedone, E; Moretti, M; De Smaele, E - 01a Articolo in rivista
rivista: NEOPLASIA (Basingstoke: Nature Publishing Group.) pp. 1-12 - issn: 1476-5586 - wos: WOS:001144756100001 (5) - scopus: 2-s2.0-85168719034 (5)

11573/1689140 - 2023 - SCF and IL-33 regulate mouse mast cell phenotypic and functional plasticity supporting a pro-inflammatory microenvironment
Molfetta, Rosa; Lecce, Mario; Milito, Nadia D; Putro, Erisa; Pietropaolo, Giuseppe; Marangio, Caterina; Scarno, Gianluca; Moretti, Marta; De Smaele, Enrico; Santini, Tiziana; Bernardini, Giovanni; Sciume', Giuseppe; Santoni, Angela; Paolini, Rossella - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:001077733500001 (6) - scopus: 2-s2.0-85171462403 (6)

11573/1712122 - 2023 - SCF and IL-33 regulate intestinal mouse mast cell plasticity in colon cancer
Putro, Erisa; Lecce, Mario; Milito, Nadia D.; Pietropaolo, Giuseppe; Marangio, Caterina; Scarno, Gianluca; Moretti, Marta; De Smaele, Enrico; Santini, Tiziana; Bernardini, Giovanni; Sciume, Giuseppe; Santoni, Angela; Molfetta, Rosa; Paolini, Rossella - 04f Poster
congresso: XIV NATIONAL SIICA CONGRESS 2023 (Verona,Italy)
libro: XIV NATIONAL SIICA CONGRESS 2023 - ()

11573/1649451 - 2022 -  Combined treatment with inhibitors of ErbB Receptors and Hh signaling pathways is more effective than single treatment in reducing the growth of malignant mesothelioma both in vitro and in vivo
Bei, Roberto; Benvenuto, Monica; Focaccetti, Chiara; Fazi, Sara; Moretti, Marta; Nardozi, Daniela; Angiolini, Valentina; Ciuffa, Sara; Cifaldi, Loredana; Carrano, Raffaele; Palumbo, Camilla; Miele, Martino Tony; Bei, Riccardo; Barillari, Giovanni; Manzari, Vittorio; De Smaele, Enrico; Modesti, Andrea; Masuelli, Laura - 01a Articolo in rivista
rivista: JOURNAL OF TRANSLATIONAL MEDICINE (London: BioMed Central, London) pp. 286- - issn: 1479-5876 - wos: WOS:000815628200002 (5) - scopus: 2-s2.0-85132968425 (6)

11573/1614498 - 2022 - Islet regeneration and pancreatic duct glands in human and experimental diabetes
Overi, Diletta; Carpino, Guido; Moretti, Marta; Franchitto, Antonio; Nevi, Lorenzo; Onori, Paolo; De Smaele, Enrico; Federici, Luca; Santorelli, Daniele; Maroder, Marella; Reid, Lola M; Cardinale, Vincenzo; Alvaro, Domenico; Gaudio, Eugenio - 01a Articolo in rivista
rivista: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. 1-12 - issn: 2296-634X - wos: WOS:000761005400001 (5) - scopus: 2-s2.0-85125245868 (6)

11573/1655666 - 2022 - A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma
Petroni, Marialaura; Fabretti, Francesca; Di Giulio, Stefano; Nicolis Di Robilant, Vittoria; La Monica, Veronica; Moretti, Marta; Belardinilli, Francesca; Bufalieri, Francesca; Coppa, Anna; Paci, Paola; Corsi, Alessandro; De Smaele, Enrico; Coni, Sonia; Canettieri, Gianluca; Di Marcotullio, Lucia; Wang, Zhao‐Qi; Giannini, Giuseppe - 01a Articolo in rivista
rivista: NEUROPATHOLOGY & APPLIED NEUROBIOLOGY (Oxford England: Blackwell Science) pp. - - issn: 1365-2990 - wos: WOS:000837995000001 (3) - scopus: 2-s2.0-85137005708 (3)

11573/1483390 - 2021 - Hypoxia, endoplasmic reticulum stress and chemoresistance: dangerous liaisons
Akman, M.; Belisario, D. C.; Salaroglio, I. C.; Kopecka, J.; Donadelli, M.; De Smaele, E.; Riganti, C. - 01g Articolo di rassegna (Review)
rivista: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. - - issn: 1756-9966 - wos: WOS:000606743500001 (93) - scopus: 2-s2.0-85099034682 (97)

11573/1554619 - 2021 - The emerging role of the KCTD proteins in cancer
Angrisani, A.; Di Fiore, A.; De Smaele, E.; Moretti, M. - 01g Articolo di rassegna (Review)
rivista: CELL COMMUNICATION AND SIGNALING (BioMed Central, London) pp. - - issn: 1478-811X - wos: WOS:000656209900003 (43) - scopus: 2-s2.0-85106315873 (43)

11573/1546777 - 2021 - Specific Protein 1 and p53 Interplay Modulates the Expression of the KCTD-Containing Cullin3 Adaptor Suppressor of Hedgehog 2
Angrisani, A.; Di Fiore, A.; Di Trani, C. A.; Fonte, S.; Petroni, M.; Lospinoso Severini, L.; Bordin, F.; Belloni, L.; Ferretti, E.; Canettieri, G.; Moretti, M.; De Smaele, E. - 01a Articolo in rivista
rivista: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. 1-16 - issn: 2296-634X - wos: WOS:000642096200001 (5) - scopus: 2-s2.0-85104623989 (5)

11573/1534264 - 2021 - Functional cooperation between ASK1 and p21Waf1/Cip1 in the balance of cell-cycle arrest, cell death and tumorigenesis of stressed keratinocytes
De Blasio, Carlo; Verma, Nagendra; Moretti, Marta; Cialfi, Samantha; Zonfrilli, Azzurra; Franchitto, Matteo; Truglio, Federica; De Smaele, Enrico; Ichijo, Hidenori; Naguro, Isao; Screpanti, Isabella; Talora, Claudio - 01a Articolo in rivista
rivista: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. 1-8 - issn: 2058-7716 - wos: WOS:000639923300002 (3) - scopus: 2-s2.0-85104240779 (3)

11573/1546775 - 2021 - Microbiological profiles of dental implants in metabolic syndrome patients: a case-control study
Di Murro, B.; Moretti, M.; De Smaele, E.; Letizia, C.; Lubrano, C.; Passarelli, P. C.; D'addona, A.; Pompa, G.; Papi, P. - 01a Articolo in rivista
rivista: ANTIBIOTICS (Basel : MDPI) pp. - - issn: 2079-6382 - wos: WOS:000642668500001 (6) - scopus: 2-s2.0-85104669377 (8)

11573/1447549 - 2021 - Downregulation of miR-326 and its host gene β-arrestin1 induces pro survival activity of E2F1 and promotes medulloblastoma growth
Miele, Evelina; Po, Agnese; Mastronuzzi, Angela; Carai, Andrea; Besharat, Zein Mersini; Pediconi, Natalia; Abballe, Luana; Catanzaro, Giuseppina; Sabato, Claudia; De Smaele, Enrico; Canettieri, Gianluca; Di Marcotullio, Lucia; Vacca, Alessandra; Mai, Antonello; Levrero, Massimo; Pfister, Stefan M; Kool, Marcel; Giangaspero, Felice; Locatelli, Franco; Ferretti, Elisabetta - 01a Articolo in rivista
rivista: MOLECULAR ONCOLOGY (Amsterdam : Elsevier Science) pp. - - issn: 1574-7891 - wos: WOS:000603687900001 (8) - scopus: 2-s2.0-85098446777 (8)

11573/1563720 - 2021 - Methods for modulating the pathway of NF-κB using short hairpin RNA (ShRNA)
Moretti, M.; Di Francesco, B.; Nolfi, M. D. V.; Angrisani, A.; De Smaele, E. - 02a Capitolo o Articolo
libro: Methods in Molecular Biology - (978-1-0716-1668-0; 978-1-0716-1669-7)

11573/1471539 - 2020 - Hypoxia dictates metabolic rewiring of tumors: implications for chemoresistance
Belisario, D. C.; Kopecka, J.; Pasino, M.; Akman, M.; De Smaele, E.; Donadelli, M.; Riganti, C. - 01g Articolo di rassegna (Review)
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000602288500001 (66) - scopus: 2-s2.0-85097514475 (73)

11573/1471575 - 2020 - Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation
Coni, S.; Serrao, S. M.; Yurtsever, Z. N.; Di Magno, L.; Bordone, R.; Bertani, C.; Licursi, V.; Ianniello, Z.; Infante, P.; Moretti, M.; Petroni, M.; Guerrieri, F.; Fatica, A.; Macone, A.; De Smaele, E.; Di Marcotullio, L.; Giannini, G.; Maroder, M.; Agostinelli, E.; Canettieri, G. - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000597627300001 (45) - scopus: 2-s2.0-85097416564 (47)

11573/1364966 - 2020 - Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module
Di Magno, L.; Manni, S.; Di Pastena, F.; Coni, S.; Macone, A.; Cairoli, S.; Sambucci, M.; Infante, P.; Moretti, M.; Petroni, M.; Nicoletti, C.; Capalbo, C.; De Smaele, E.; Di Marcotullio, L.; Giannini, G.; Battistini, L.; Goffredo, B. M.; Iorio, E.; Agostinelli, E.; Maroder, M.; Canettieri, G. - 01a Articolo in rivista
rivista: CELL REPORTS (Elsevier B.V. Cambridge MA: Cell Press) pp. 1735-1752 - issn: 2211-1247 - wos: WOS:000513920800008 (41) - scopus: 2-s2.0-85079335561 (41)

11573/1375030 - 2020 - From single gene analysis to single cell profiling: a new era for precision medicine
Di Martino, Maria Teresa; Meschini, Stefania; Scotlandi, Katia; Riganti, Chiara; De Smaele, Enrico; Zazzeroni, Francesca; Donadelli, Massimo; Leonetti, Carlo; Caraglia, Michele - 01a Articolo in rivista
rivista: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. 48- - issn: 1756-9966 - wos: WOS:000519018900001 (6) - scopus: 2-s2.0-85081530829 (7)

11573/1444376 - 2020 - Hedgehog-GLI signalling promotes chemoresistance through the regulation of ABC transporters in colorectal cancer cells
Po, A.; Citarella, A.; Catanzaro, G.; Besharat, Z. M.; Trocchianesi, S.; Gianno, F.; Sabato, C.; Moretti, M.; De Smaele, E.; Vacca, A.; Fiori, M. E.; Ferretti, E. - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000567440100012 (31) - scopus: 2-s2.0-85089600783 (33)

11573/1408475 - 2020 - Che-1/AATF binds to RNA polymerase I machinery and sustains ribosomal RNA gene transcription
Sorino, Cristina; Catena, Valeria; Bruno, Tiziana; De Nicola, Francesca; Scalera, Stefano; Bossi, Gianluca; Fabretti, Francesca; Mano, Miguel; De Smaele, Enrico; Fanciulli, Maurizio; Iezzi, Simona - 01a Articolo in rivista
rivista: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. 5891-5906 - issn: 0305-1048 - wos: WOS:000574284500014 (11) - scopus: 2-s2.0-85086523409 (12)

11573/1210601 - 2019 - Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation
Antonucci, Laura; Di Magno, Laura; D'amico, Davide; Manni, Simona; Serrao, Silvia Maria; Di Pastena, Fiorella; Bordone, Rosa; Yurtsever, Zuleyha Nihan; Caimano, Miriam; Petroni, Marialaura; Giorgi, Alessandra; Schininà, Maria Eugenia; Yates Iii, John R; Di Marcotullio, Lucia; De Smaele, Enrico; Checquolo, Saula; Capalbo, Carlo; Agostinelli, Enzo; Maroder, Marella; Coni, Sonia; Canettieri, Gianluca - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF ONCOLOGY (National Hellenic Research Foundation:48 Vas Constatinou Avenue, Athens 11635 Greece:011 30 1 7241505, Fax: 011 30 1 7241505Editore attuale:PROFESSOR D A SPANDIDOS, 1, S MERKOURI ST, EDITORIAL OFFICE,, ATHENS, GREECE, 116 35. Editore precedente:Editorial Academy of the International Journal of Oncology.) pp. 505-514 - issn: 1019-6439 - wos: WOS:000454923900009 (25) - scopus: 2-s2.0-85058877986 (27)

11573/1304369 - 2019 - ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP
Bufalieri, F.; Infante, P.; Bernardi, F.; Caimano, M.; Romania, P.; Moretti, M.; Lospinoso Severini, L.; Talbot, J.; Melaiu, O.; Tanori, M.; Di Magno, L.; Bellavia, D.; Capalbo, C.; Puget, S.; De Smaele, E.; Canettieri, G.; Guardavaccaro, D.; Busino, L.; Peschiaroli, Angelo; Pazzaglia, S.; Giannini, G.; Melino, G.; Locatelli, F.; Gulino, A.; Ayrault, O.; Fruci, D.; Di Marcotullio, L. - 01a Articolo in rivista
rivista: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. 1-15 - issn: 2041-1723 - wos: WOS:000476877400003 (40) - scopus: 2-s2.0-85069646549 (41)

11573/1289624 - 2019 - EZH2, JMJD3 and UTX epigenetically regulate hepatic plasticity inducing retro-differentiation and proliferation of liver cells
Pediconi, Natalia; Lupacchini, Leonardo; Salerno, Debora; Angrisani, Annapaola; Peruzzi, Giovanna; De Smaele, Enrico; Levrero, Massimo; Belloni, Laura - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. 518- - issn: 2041-4889 - wos: WOS:000476589200001 (20) - scopus: 2-s2.0-85068608184 (22)

11573/1343151 - 2019 - SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors
Petroni, Marialaura; Sahùn Roncero, Maria; Ramponi, Valentina; Fabretti, Francesca; Nicolis Di Robilant, Vittoria; Moretti, Marta; Alfano, Vincenzo; Corsi, Alessandro; De Panfilis, Simone; Giubettini, Maria; Di Giulio, Stefano; Capalbo, Carlo; Belardinilli, Francesca; Coppa, Anna; Sardina, Francesca; Colicchia, Valeria; Pedretti, Flaminia; Infante, Paola; Cardinali, Beatrice; Tessitore, Alessandra; Canettieri, Gianluca; De Smaele, Enrico; Giannini, Giuseppe - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000508896900014 (4) - scopus: 2-s2.0-85077063979 (4)

11573/1408473 - 2019 - The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway
Scicchitano, S.; Giordano, M.; Lucchino, V.; Montalcini, Y.; Chiarella, E.; Aloisio, A.; Codispoti, B.; Zoppoli, P.; Melocchi, V.; Bianchi, F.; De Smaele, E.; Mesuraca, M.; Morrone, G.; Bond, H. M. - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000488854900005 (18) - scopus: 2-s2.0-85072697834 (19)

11573/1338842 - 2019 - KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2
Spiombi, Eleonora; Angrisani, Annapaola; Fonte, Simone; De Feudis, Giuseppina; Fabretti, Francesca; Cucchi, Danilo; Izzo, Mariapaola; Infante, Paola; Miele, Evelina; Po, Agnese; Di Magno, Laura; Magliozzi, Roberto; Guardavaccaro, Daniele; Maroder, Marella; Canettieri, Gianluca; Giannini, Giuseppe; Ferretti, Elisabetta; Gulino, Alberto; Di Marcotullio, Lucia; Moretti, Marta; De Smaele, Enrico - 01a Articolo in rivista
rivista: ONCOGENESIS (London Nature Publishing Group) pp. 64- - issn: 2157-9024 - wos: WOS:000494423700001 (21) - scopus: 2-s2.0-85074354238 (22)

11573/1182080 - 2018 - Numb Isoforms Deregulation in Medulloblastoma and Role of p66 Isoform in Cancer and Neural Stem Cells
Abballe, Luana; Mastronuzzi, Angela; Miele, Evelina; Carai, Andrea; Besharat, Zein Mersini; Moretti, Marta; De Smaele, Enrico; Giangaspero, Felice; Locatelli, Franco; Ferretti, Elisabetta; Po, Agnese - 01a Articolo in rivista
rivista: FRONTIERS IN PEDIATRICS (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-2360 - wos: WOS:000449006100001 (11) - scopus: 2-s2.0-85057200346 (10)

11573/1292255 - 2018 - STUDY OF THE TRANSCRIPTIONAL REGULATION OF THE ONCOSUPPRESSOR KCASH2
Angrisani, A.; Di Trani, Claudia Augusta; Moretti, M.; Izzo, M.; Ciocia, Annagiulia; Fonte, Simone; De Smaele, E. - 01h Abstract in rivista
rivista: JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS (Wichtig Editore:Via Friuli 72 74, I 20135 Milan Italy:011 39 02 5455122, 011 39 2 55195443, EMAIL: info@wichtig-publisher.com, INTERNET: http://www.wichtig-publisher.com, Fax: 011 39 2 55195971) pp. 145-145 - issn: 0393-974X - wos: (0) - scopus: (0)

11573/1079555 - 2018 - Foxm1 controls a pro-stemness microRNA network in neural stem cells
Besharat, Zein Mersini; Abballe, Luana; Cicconardi, Francesco; Bhutkar, Arjun; Grassi, Luigi; Le Pera, Loredana; Moretti, Marta; Chinappi, Mauro; D'andrea, Daniel; Mastronuzzi, Angela; Ianari, Alessandra; Vacca, Alessandra; De Smaele, Enrico; Locatelli, Franco; Po, Agnese; Miele, Evelina; Ferretti, Elisabetta - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 3523- - issn: 2045-2322 - wos: WOS:000425934200011 (31) - scopus: 2-s2.0-85042534913 (33)

11573/1085264 - 2018 - Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis
Infante, Paola; Faedda, Roberta; Bernardi, Flavia; Bufalieri, Francesca; Lospinoso Severini, Ludovica; Alfonsi, Romina; Mazzà, Daniela; Siler, Mariangela; Coni, Sonia; Po, Agnese; Petroni, Marialaura; Ferretti, Elisabetta; Mori, Mattia; De Smaele, Enrico; Canettieri, Gianluca; Capalbo, Carlo; Maroder, Marella; Screpanti, Isabella; Kool, Marcel; Pfister, Stefan M.; Guardavaccaro, Daniele; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
rivista: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. ...-... - issn: 2041-1723 - wos: WOS:000426899000002 (47) - scopus: 2-s2.0-85044632076 (50)

11573/1174165 - 2018 - Sonic hedgehog medulloblastoma cancer stem cells mirnome and transcriptome highlight novel functional networks
Po, A.; Abballe, L.; Sabato, Claudia; Gianno, F.; Chiacchiarini, Martina; Catanzaro, G.; De Smaele, E.; Giangaspero, F.; Ferretti, E.; Miele, E.; Besharat, Z. M. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000442869800178 (14) - scopus: 2-s2.0-85052083051 (15)

11573/1602341 - 2017 - Corrigendum: Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma
Coni, S.; Mancuso, A. B.; Di Magno, L.; Sdruscia, G.; Manni, S.; Serrao, S. M.; Rotili, D.; Spiombi, E.; Bufalieri, F.; Petroni, M.; Kusio-Kobialka, M.; De Smaele, E.; Ferretti, E.; Capalbo, C.; Mai, A.; Niewiadomski, P.; Screpanti, I.; Di Marcotullio, L.; Canettieri, G. - 01b Commento, Erratum, Replica e simili
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000399974300001 (5) - scopus: 2-s2.0-85068766477 (4)

11573/1560468 - 2017 - Targeting Gli acetylation in Shh-medulloblastoma: A successful preclinical approach
Coni, S; Di Magno, L; Mancuso, Ab; Sdruscia, G; Manni, S; Serrao, Sm; Di Marcotullio, L; De Smaele, E; Ferretti, E; Canettieri, G - 01h Abstract in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (D. A. Spandidos. Athens) pp. S26-S26 - issn: 1107-3756 - wos: WOS:000411659300088 (0) - scopus: (0)

11573/946157 - 2017 - Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.
Coni, Sonia; Mancuso, Anna Barbara; Di Magno, L; Sdruscia, Giulia; Manni, Simona; Serrao, Silvia Maria; Rotili, Dante; Spiombi, Eleonora; Bufalieri, Francesca; Petroni, Marialaura; Kusio Kobialka, M; De Smaele, Enrico; Ferretti, Elisabetta; Capalbo, Carlo; Mai, Antonello; Niewiadomski, P; Screpanti, Isabella; Di Marcotullio, Lucia; Canettieri, Gianluca - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 44079- - issn: 2045-2322 - wos: WOS:000396136700001 (54) - scopus: 2-s2.0-85014895304 (54)

11573/933971 - 2017 - Curcumin blocks autophagy and activates apoptosis of malignant mesothelioma cell lines and increases the survival of mice intraperitoneally transplanted with a malignant mesothelioma cell line
Masuelli, Laura; Benvenuto, Monica; Di Stefano, Enrica; Mattera, Rosanna; Fantini, Massimo; De Feudis, Giuseppina; De Smaele, Enrico; Tresoldi, Ilaria; Giganti, Maria Gabriella; Modesti, Andrea; Bei, Roberto - 01a Articolo in rivista
rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 34405-34422 - issn: 1949-2553 - wos: WOS:000402051700038 (64) - scopus: 2-s2.0-85019847692 (71)

11573/1024175 - 2017 - β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells
Miele, Evelina; Po, Agnese; Begalli, Federica; Antonucci, Laura; Mastronuzzi, Angela; Marras, Carlo Efisio; Carai, Andrea; Cucchi, Danilo; Abballe, Luana; Besharat, Zein Mersini; Catanzaro, Giuseppina; Infante, Paola; Di Marcotullio, Lucia; Canettieri, Gianluca; De Smaele, Enrico; Screpanti, Isabella; Locatelli, Franco; Ferretti, Elisabetta - 01a Articolo in rivista
rivista: BMC CANCER (London: BioMed Central, [2001]-) pp. 488- - issn: 1471-2407 - wos: WOS:000405865300002 (54) - scopus: 2-s2.0-85024120271 (55)

11573/952694 - 2017 - Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma
Po, Agnese; Silvano, Marianna; Miele, Evelina; Capalbo, Carlo; Eramo, A.; Salvati, V.; Todaro, M.; Besharat, Zein Mersini; Catanzaro, Giuseppina; Cucchi, Danilo; Coni, Sonia; Di Marcotullio, Lucia; Canettieri, Gianluca; Vacca, Alessandra; Stassi, G.; De Smaele, Enrico; Tartaglia, M.; Screpanti, Isabella; De Maria, R.; Ferretti, Elisabetta - 01a Articolo in rivista
rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. - - issn: 0950-9232 - wos: WOS:000407246200011 (81) - scopus: 2-s2.0-85016980676 (86)

11573/853584 - 2016 - In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.
Benvenuto, M; Masuelli, Laura; De Smaele, Enrico; Fantini, M; Mattera, Rosanna; Cucchi, Danilo; Bonanno, E; Di Stefano, Enrica; Frajese, Gv; Orlandi, A; Screpanti, Isabella; Gulino, Alberto; Modesti, A; Bei, R. - 01a Articolo in rivista
rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 9250-9270 - issn: 1949-2553 - wos: WOS:000375618100061 (97) - scopus: 2-s2.0-84961590447 (101)

11573/863407 - 2016 - The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint
Di Magno, Laura; Basile, Alessio; Coni, Sonia; Manni, Simona; Sdruscia, Giulia; D'amico, Davide; Antonucci, Laura; Infante, Paola; De Smaele, Enrico; Cucchi, Danilo; Ferretti, Elisabetta; Di Marcotullio, Lucia; Screpanti, Isabella; Canettieri, Gianluca - 01a Articolo in rivista
rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 9538-9549 - issn: 1949-2553 - wos: WOS:000375618100081 (39) - scopus: 2-s2.0-84961627529 (40)

11573/903195 - 2016 - The centrosomal deubiquitylase USP21 regulates Gli1 transcriptional activity and stability
Heride, Claire; Rigden, Daniel J.; Bertsoulaki, Erithelgi; Cucchi, Danilo; De Smaele, Enrico; Clague, Michael J.; Urbé, Sylvie - 01a Articolo in rivista
rivista: JOURNAL OF CELL SCIENCE (The Company of Biologists Limited:Bidder Building, 140 Cowley Road, Cambridge CB4 0DL United Kingdom:011 44 1223 420482, EMAIL: mandy@thecob.demon.co.uk, INTERNET: http://www.biologists.com, Fax: 011 44 1223 423353) pp. 4001-4013 - issn: 0021-9533 - wos: WOS:000389595600006 (36) - scopus: 2-s2.0-84995377781 (36)

11573/808783 - 2015 - Non-canonical Hedgehog/ampk-mediated control of polyamine metabolism supports neuronal and medulloblastoma cell growth
D'amico, Davide; Antonucci, Laura; Di Magno, Laura; Coni, Sonia; Sdruscia, Giulia; Macone, Alberto; Miele, Evelina; Infante, Paola; Di Marcotullio, Lucia; De Smaele, Enrico; Ferretti, Elisabetta; Ciapponi, Laura; Giangaspero, Felice; John, R. Yates Iii; Agostinelli, Enzo; Cardinali, Beatrice; Screpanti, Isabella; Gulino, Alberto; Canettieri, Gianluca - 01a Articolo in rivista
rivista: DEVELOPMENTAL CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 21-35 - issn: 1534-5807 - wos: WOS:000363076000008 (62) - scopus: 2-s2.0-84945252145 (63)

11573/649688 - 2015 - Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors
Infante, Paola; Mori, Mattia; Alfonsi, Romina; Ghirga, Francesca; Federica, Aiello; Toscano, Sara; Ingallina, Cinzia; Mariangela, Siler; Cucchi, Danilo; Po, Agnese; Miele, Evelina; Davide, D’Amico; Canettieri, Gianluca; De Smaele, Enrico; Ferretti, Elisabetta; Screpanti, Isabella; Gloria Uccello, Barretta; Maurizio, Botta; Botta, Bruno; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
rivista: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 200-217 - issn: 0261-4189 - wos: WOS:000347878900008 (148) - scopus: 2-s2.0-84921293370 (152)

11573/648414 - 2014 - Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth
Di Magno, Laura; Daniela, Manzi; D'amico, Davide; Coni, Sonia; Macone, Alberto; Infante, Paola; Di Marcotullio, Lucia; De Smaele, Enrico; Ferretti, Elisabetta; Screpanti, Isabella; Agostinelli, Enzo; Gulino, Alberto; Canettieri, Gianluca - 01a Articolo in rivista
rivista: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 3404-3413 - issn: 1538-4101 - wos: WOS:000348313100013 (39) - scopus: 2-s2.0-84915795126 (40)

11573/516975 - 2013 - Inhibition of ErbB receptors, Hedgehog and NF-kappaB signaling by polyphenols in cancer
Benvenuto, Monica; M., Fantini; Masuelli, Laura; De Smaele, Enrico; F., Zazzeroni; I., Tresoldi; G., Calabrese; F., Galvano; Andrea, Modesti; Roberto, Bei - 01a Articolo in rivista
rivista: FRONTIERS IN BIOSCIENCE (Frontiers in Bioscience:PO Box 160:Albertson, NY 11507:(516)484-2831, (516)484-0813, EMAIL: fbsadmin@bioscience.org, INTERNET: http://www.bioscience.org, Fax: (516)484-2831) pp. 1290-1310 - issn: 1093-9946 - wos: WOS:000321014400009 (28) - scopus: 2-s2.0-84880529305 (27)

11573/543166 - 2013 - Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy
Coni, Sonia; Antonucci, Laura; D'amico, Davide; Di Magno, Laura; Infante, Paola; De Smaele, Enrico; Giannini, Giuseppe; Di Marcotullio, Lucia; Screpanti, Isabella; Gulino, Alberto; Canettieri, Gianluca - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e65718- - issn: 1932-6203 - wos: WOS:000321099000097 (59) - scopus: 2-s2.0-84878804952 (61)

11573/527314 - 2013 - microRNA-17-92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1
Garg, Neha; Po, Agnese; Miele, Evelina; Campese, Antonio Francesco; Begalli, Federica; Marianna, Silvano; Infante, Paola; Capalbo, Carlo; De Smaele, Enrico; Canettieri, Gianluca; Di Marcotullio, Lucia; Screpanti, Isabella; Ferretti, Elisabetta; Gulino, Alberto - 01a Articolo in rivista
rivista: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 2819-2832 - issn: 0261-4189 - wos: WOS:000326504900006 (56) - scopus: 2-s2.0-84887046837 (56)

11573/527250 - 2013 - PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress
Mazza, Daniele; Infante, Paola; Colicchia, Valeria; Greco, Azzura; Alfonsi, Romina; M., Siler; Antonucci, Laura; Po, Agnese; De Smaele, Enrico; Ferretti, Elisabetta; Capalbo, Carlo; Bellavia, Diana; Canettieri, Gianluca; Giannini, Giuseppe; Screpanti, Isabella; Gulino, Alberto; Di Marcotullio, Lucia - 01a Articolo in rivista
rivista: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 1688-1697 - issn: 1350-9047 - wos: WOS:000327010600012 (75) - scopus: 2-s2.0-84887619992 (83)

11573/500890 - 2012 - Hedgehog signaling pathway and its targets for treatment in basal cell carcinoma
Cucchi, Danilo; Occhione, Maria Anna; Gulino, Alberto; De Smaele, Enrico - 01g Articolo di rassegna (Review)
rivista: JOURNAL OF EXPERIMENTAL PHARMACOLOGY ([Auckland, N.Z.] : Dove Medical Press, c2009-) pp. 173-185 - issn: 1179-1454 - wos: (0) - scopus: 2-s2.0-85016507936 (14)

11573/444530 - 2012 - Hedgehog/Gli Control by Ubiquitination/Acetylation Interplay
Gulino, Alberto; Di Marcotullio, Lucia; Canettieri, Gianluca; De Smaele, Enrico; Screpanti, Isabella - 02a Capitolo o Articolo
libro: Hedgehog Signaling - (9780123946225)

11573/404594 - 2011 - NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration
Claudio, Mauro; Shi Chi, Leow; Elena, Anso; Sonia, Rocha; Anil K., Thotakura; Laura, Tornatore; Moretti, Marta; De Smaele, Enrico; Amer A., Beg; Vinay, Tergaonkar; Navdeep S., Chandel; Guido, Franzoso - 01a Articolo in rivista
rivista: NATURE CELL BIOLOGY (Nature America Incorporated:345 Park Avenue South, 6th Floor:New York, NY 10010:(888)331-6288, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: (212)689-9108) pp. 1272-1279 - issn: 1465-7392 - wos: WOS:000295617900018 (297) - scopus: 2-s2.0-80053539605 (307)

11573/377914 - 2011 - Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma
De Smaele, Enrico; Di Marcotullio, Lucia; Moretti, Marta; Pelloni, Marianna; Occhione, Maria Anna; Infante, Paola; Cucchi, Danilo; Greco, Azzura; Pietrosanti, Laura; J., Todorovic; Coni, Sonia; Canettieri, Gianluca; Ferretti, Elisabetta; R., Bei; Maroder, Marella; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
rivista: NEOPLASIA (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 374-385 - issn: 1522-8002 - wos: WOS:000289529400009 (78) - scopus: 2-s2.0-79952438480 (80)

11573/377915 - 2011 - Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal
Di Marcotullio, Lucia; Greco, Azzura; Mazza', Daniela; Canettieri, Gianluca; Pietrosanti, Laura; Infante, Paola; Coni, Sonia; Moretti, Marta; De Smaele, Enrico; Ferretti, Elisabetta; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 65-76 - issn: 0950-9232 - wos: WOS:000285959300006 (92) - scopus: 2-s2.0-78650983824 (95)

11573/428150 - 2011 - Delta-cell-specific expression of hedgehog pathway Ptch1 receptor in murine and human endocrine pancreas
F. A., Grieco; Moretti, Marta; G., Sebastiani; L., Galleri; I., Spagnuolo; Scafetta, Gaia; Gulino, Alberto; De Smaele, Enrico; Maroder, Marella; Francesco, Dotta - 01a Articolo in rivista
rivista: DIABETES/METABOLISM RESEARCH AND REVIEWS (John Wiley & Sons Limited:1 Oldlands Way, Bognor Regis, P022 9SA United Kingdom:011 44 1243 779777, EMAIL: cs-journals@wiley.co.uk, INTERNET: http://www.wiley.co.uk, Fax: 011 44 1243 843232) pp. 755-760 - issn: 1520-7552 - wos: WOS:000300108000006 (7) - scopus: 2-s2.0-80855131248 (7)

11573/377916 - 2011 - Molecular organization of the cullin E3 ligase adaptor KCTD11
Stefania, Correale; Luciano, Pirone; Di Marcotullio, Lucia; De Smaele, Enrico; Greco, Azzura; Mazza', Daniela; Moretti, Marta; Vincenzo, Alterio; Luigi, Vitagliano; Sonia Di, Gaetano; Gulino, Alberto; Emilia Maria, Pedone - 01a Articolo in rivista
rivista: BIOCHIMIE (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 715-724 - issn: 0300-9084 - wos: WOS:000289182400009 (48) - scopus: 2-s2.0-79952438310 (49)

11573/401408 - 2010 - Histone deacetylase and Cullin3-REN KCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation
Canettieri, Gianluca; Di Marcotullio, Lucia; Greco, Azzura; Coni, Sonia; Antonucci, Laura; Infante, Paola; Pietrosanti, Laura; De Smaele, Enrico; Ferretti, Elisabetta; Miele, Evelina; Pelloni, Marianna; Giuseppina De, Simone; Emilia Maria, Pedone; Paola, Gallinari; Giorgi, Alessandra; Christian, Steinkuhler; Luigi, Vitagliano; Carlo, Pedone; Schinina', Maria Eugenia; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
rivista: NATURE CELL BIOLOGY (Nature America Incorporated:345 Park Avenue South, 6th Floor:New York, NY 10010:(888)331-6288, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: (212)689-9108) pp. 132-U91 - issn: 1465-7392 - wos: WOS:000274139400007 (284) - scopus: 2-s2.0-75949106376 (290)

11573/224433 - 2010 - MicroRNAs as biomarkers for CNS cancer and other disorders
De Smaele, Enrico; Ferretti, Elisabetta; Gulino, Alberto - 01a Articolo in rivista
rivista: BRAIN RESEARCH (Amsterdam; Lausanne; New York; Oxford; Shannon; Tokyo: Elsevier) pp. 100-111 - issn: 0006-8993 - wos: WOS:000279096700011 (111) - scopus: 2-s2.0-77952583639 (116)

11573/229101 - 2010 - Vismodegib, a small-molecule inhibitor of the Hedgehog pathway for the treatment of advanced cancers
De Smaele, Enrico; Ferretti, Elisabetta; Gulino, Alberto - 01a Articolo in rivista
rivista: CURRENT OPINION IN INVESTIGATIONAL DRUGS (Current Patents Limited:34-42 Cleveland Street, Middlesex, London W1P 6LB United Kingdom:011 44 20 73230323, EMAIL: info@current-patents.com, INTERNET: http://www.current-patents.com/, Fax: 011 44 20 75805646) pp. 707-718 - issn: 1472-4472 - wos: WOS:000277891000012 (75) - scopus: 2-s2.0-77952903058 (81)

11573/364193 - 2010 - Hedgehog controls neural stem cells through p53-independent regulation of Nanog
Po, Agnese; Ferretti, Elisabetta; Miele, Evelina; De Smaele, Enrico; Arianna, Paganelli; Canettieri, Gianluca; Coni, Sonia; Di Marcotullio, Lucia; Biffoni, Marco; Luca, Massimi; Concezio Di, Rocco; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
rivista: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 2646-2658 - issn: 0261-4189 - wos: WOS:000280658900017 (186) - scopus: 2-s2.0-77955362243 (193)

11573/224364 - 2009 - MicroRNA profiling in human medulloblastoma
Ferretti, Elisabetta; De Smaele, Enrico; Po, Agnese; Di Marcotullio, Lucia; Emanuele, Tosi; Maria Salome B., Espinola; Concezio Di, Rocco; Riccardo, Riccardi; Giangaspero, Felice; Farcomeni, Alessio; Nofroni, Italo; Pietro, Laneve; Ubaldo, Gioia; Elisa, Caffarelli; Bozzoni, Irene; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF CANCER (Hoboken N.J.: Wiley New York NY: Wiley-Liss) pp. 568-577 - issn: 0020-7136 - wos: WOS:000262205400009 (262) - scopus: 2-s2.0-58149279841 (268)

11573/226956 - 2009 - Glucocorticoids and neonatal brain injury: The hedgehog connection
Gulino, Alberto; De Smaele, Enrico; Ferretti, Elisabetta - 01a Articolo in rivista
rivista: THE JOURNAL OF CLINICAL INVESTIGATION (American Society for Clinical Investigation:PO Box 7226:Ann Arbor, MI 48107:(734)222-6050, EMAIL: rhickman@the-jci.org, INTERNET: http://www.jci.org, Fax: (734)222-6058) pp. 243-246 - issn: 0021-9738 - wos: WOS:000263084400003 (15) - scopus: 2-s2.0-61749092250 (16)

11573/227411 - 2009 - Hedgehog signalling in colon cancer and stem cells.
Gulino, Alberto; Ferretti, Elisabetta; De Smaele, Enrico - 01a Articolo in rivista
rivista: EMBO MOLECULAR MEDICINE (Chichester : Wiley-Blackwell, 2009-) pp. 300-302 - issn: 1757-4676 - wos: WOS:000273563400002 (54) - scopus: 2-s2.0-77952911825 (59)

11573/362261 - 2008 - An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma
De Smaele, Enrico; C., Fragomeli; Ferretti, Elisabetta; Pelloni, Marianna; Po, Agnese; Canettieri, Gianluca; Coni, Sonia; Di Marcotullio, Lucia; Greco, Azzura; Moretti, Marta; C., Di Rocco; S., Pazzaglia; Maroder, Marella; Screpanti, Isabella; Giannini, Giuseppe; Gulino, Alberto - 01a Articolo in rivista
rivista: NEOPLASIA (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 89-98 - issn: 1522-8002 - wos: WOS:000253614300009 (45) - scopus: 2-s2.0-38649132910 (45)

11573/359122 - 2008 - Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells
Ferretti, Elisabetta; De Smaele, Enrico; Miele, Evelina; Pietro, Laneve; Po, Agnese; Pelloni, Marianna; Arianna, Paganelli; Di Marcotullio, Lucia; Elisa, Caffarelli; Screpanti, Isabella; Bozzoni, Irene; Gulino, Alberto - 01a Articolo in rivista
rivista: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 2616-2627 - issn: 0261-4189 - wos: WOS:000259891300014 (275) - scopus: 2-s2.0-53549129980 (288)

11573/360501 - 2007 - Multiple ubiquitin-dependent processing pathways regulate hedgehog/gli signaling: implications for cell development and tumorigenesis.
Di Marcotullio, Lucia; Ferretti, Elisabetta; Greco, Azzura; De Smaele, Enrico; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
rivista: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 390-393 - issn: 1538-4101 - wos: WOS:000245495600002 (31) - scopus: 2-s2.0-33847769746 (30)

11573/239202 - 2007 - Hedgehog signaling pathway in neural development and disease
Gulino, Alberto; Di Marcotullio, Lucia; Ferretti, Elisabetta; De Smaele, Enrico; Screpanti, Isabella - 01a Articolo in rivista
rivista: PSYCHONEUROENDOCRINOLOGY (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. S52-S56 - issn: 0306-4530 - wos: WOS:000249718600011 (33) - scopus: 2-s2.0-34547656204 (35)
congresso: Lille Summer School in Neuroscience (Lille, FRANCE)

11573/240721 - 2007 - Insights into the structural basis of the GADD45 beta-mediated inactivation of the JNK kinase, MKK7/JNKK2
Papa, S; Monti, Sm; Vitale, Rm; Bubici, C; Jayawardena, S; Alvarez, K; De Smaele, Enrico; Dathan, N; Pedone, C; Ruvo, M; Franzoso, G. - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 19029-19041 - issn: 0021-9258 - wos: WOS:000247475300045 (56) - scopus: 2-s2.0-34547102525 (61)

11573/55677 - 2006 - Numb is a suppressor of Hedgehog signaling and targets Gli1 for Itch-dependent ubiquitination.
Di Marcotullio, L; Ferretti, Elisabetta; Greco, A; De Smaele, Enrico; Po, Agnese; Alimandi, Maurizio; Giannini, G; Maroder, M; Screpanti, I; And Gulino, A. - 04b Atto di convegno in volume
congresso: EMBO Workshop Hedgehog-Gli signaling in cancer and stem cells (Roma)
libro: EMBO WORKSHOP ON HEDGEHOG-GLI SIGNALING IN CANCER AND STEM CELLS. - ()

11573/234575 - 2006 - Suppressors of Hedgehog signalling: linking aberrant development of neural progenitors to tumorigenesis.
Di Marcotullio, Lucia; Ferretti, Elisabetta; De Smaele, Enrico; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
rivista: MOLECULAR NEUROBIOLOGY (Humana Press Incorporated:999 Riverview Drive, Suite 208:Totowa, NJ 07512:(973)256-1699, EMAIL: lglasner@humanapr.com, INTERNET: http://www.humanapress.com, Fax: (973)256-8341) pp. 193-204 - issn: 0893-7648 - wos: WOS:000250119900004 (18) - scopus: 2-s2.0-33847084412 (23)

11573/364857 - 2006 - Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch- dependent ubiquitination
Di Marcotullio, Lucia; Ferretti, Elisabetta; Greco, Azzura; De Smaele, Enrico; Po, Agnese; Maria Anna, Sico; Alimandi, Maurizio; Giannini, Giuseppe; Maroder, Marella; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
rivista: NATURE CELL BIOLOGY (Nature America Incorporated:345 Park Avenue South, 6th Floor:New York, NY 10010:(888)331-6288, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: (212)689-9108) pp. 1415-U68 - issn: 1465-7392 - wos: WOS:000242419800018 (243) - scopus: 2-s2.0-33751503224 (251)

11573/55669 - 2006 - Alternative splicing of ErbB-4 cdytoplasmic domain and regulation by hedgehog signaling identità distinct medulloblastoma subsets.
Ferretti, E; Di Marcotullio, L; Gessi, M; Mattei, T; Greco, A; Po, Agnese; De Smaele, Enrico; Giangaspero, Felice; Riccardi, R; Di Rocco, C; Pazzaglia, S; Maroder, M; Alimandi, Maurizio; Screpanti, I; And Gulino A., Roma; Italy, - 04a Atto di comunicazione a congresso
libro: EMBO WORKSHOP ON HEDGEHOG-GLI SIGNALING IN CANCER AND STEM CELLS. - ()

11573/362834 - 2006 - Alternative splicing of the ErbB-4 cytoplasmic domain and its regulation by hedgehog signaling identify distinct medulloblastoma subsets
Ferretti, Elisabetta; Di Marcotullio, Lucia; M., Gessi; T., Mattei; Greco, Azzura; Po, Agnese; De Smaele, Enrico; Giangaspero, Felice; R., Riccardi; C., Di Rocco; S., Pazzaglia; Maroder, Marella; Alimandi, Maurizio; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 7267-7273 - issn: 0950-9232 - wos: WOS:000242244700005 (40) - scopus: 2-s2.0-33751307615 (39)

11573/334484 - 2006 - Pharmacological activation of mGlu4 metabotropic glutamate receptors inhibits the growth of medulloblastomas
Iacovelli, Luisa; Arcella, A.; Battaglia, G.; Pazzaglia, S.; Aronica, E.; Spinsanti, Paola; Caruso, Alessandra Sebastiana Maria; De Smaele, Enrico; Saran, A.; Gulino, Alberto; D'onofrio, M.; Giangaspero, Felice; Nicoletti, Ferdinando - 01a Articolo in rivista
rivista: THE JOURNAL OF NEUROSCIENCE (Baltimore MD: Society of Neuroscience) pp. 8388-8397 - issn: 0270-6474 - wos: WOS:000239678800020 (68) - scopus: 2-s2.0-33748186195 (72)

11573/431889 - 2005 - Hedgehog antagonist REN(KCTD11) regulates proliferation and apoptosis of developing granule cell progenitors.
Argenti, Beatrice; R., Gallo; Di Marcotullio, Lucia; Ferretti, Elisabetta; Napolitano, Maddalena; Canterini, Sonia; De Smaele, Enrico; Greco, Azzura; Fiorenza, Maria Teresa; Maroder, Marella; Screpanti, Isabella; E., Alesse; Gulino, Alberto - 01a Articolo in rivista
rivista: THE JOURNAL OF NEUROSCIENCE (Baltimore MD: Society of Neuroscience) pp. 8338-8346 - issn: 0270-6474 - wos: WOS:000231718600024 (64) - scopus: 2-s2.0-24744446807 (65)

11573/231246 - 2005 - Hedgehog checkpoints in medulloblastoma: the chromosome 17p-deletion paradigm.
Ferretti, Elisabetta; De Smaele, Enrico; Di Marcotullio, Lucia; Screpanti, Isabella; Gulino, Alberto - 01a Articolo in rivista
rivista: TRENDS IN MOLECULAR MEDICINE (London: Elsevier Science, 2001-) pp. 537-545 - issn: 1471-4914 - wos: WOS:000234320800004 (58) - scopus: 2-s2.0-28244467388 (62)

11573/146978 - 2004 - Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species.
C. G., Pham; C., Bubici; F., Zazzeroni; S., Papa; J., Jones; K., Alvarez; S., Jayawardena; De Smaele, Enrico; R., Cong; C., Beaumont; F. M., Torti; S. V., Torti; G., Franzoso - 01a Articolo in rivista
rivista: CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 529-542 - issn: 0092-8674 - wos: WOS:000225183200011 (553) - scopus: 2-s2.0-8344260568 (583)

11573/232498 - 2004 - Chromosome 17p Deletion in Human Medulloblastoma: A Missing Checkpoint in the Hedgehog Pathway
De Smaele, Enrico; Di Marcotullio, Lucia; Ferretti, Elisabetta; Screpanti, Isabella; Alesse, E; Gulino, Alberto - 01a Articolo in rivista
rivista: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 1263-1266 - issn: 1538-4101 - wos: WOS:000225590800015 (33) - scopus: 2-s2.0-13944275921 (32)

11573/233088 - 2004 - REN KCTD11 is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma.
Di Marcotullio, Lucia; Ferretti, Elisabetta; De Smaele, Enrico; Argenti, B.; Mincione, C.; Zazzeroni, F.; Gallo, R.; Masuelli, Laura; Napolitano, Maddalena; Maroder, Marella; Modesti, A.; Giangaspero, Felice; Screpanti, Isabella; Alesse, E.; Gulino, Alberto - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 10833-10838 - issn: 0027-8424 - wos: WOS:000222842700062 (155) - scopus: 2-s2.0-3242722919 (163)

11573/145361 - 2004 - Gadd45beta mediates the nf-kappab suppression of jnk signalling by targeting mkk7/jnkk2
Papa, S; Zazzeroni, F; Bubici, C; Jayawardena, S; Alvarez, K; Matsuda, S; Nguyen D., U; Pham C., G; Nelsbach A., H; Melis, T; De Smaele, Enrico; Tang W., J; D'adamio, L; Franzoso, G. - 01a Articolo in rivista
rivista: NATURE CELL BIOLOGY (Nature America Incorporated:345 Park Avenue South, 6th Floor:New York, NY 10010:(888)331-6288, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: (212)689-9108) pp. 146-153 - issn: 1465-7392 - wos: WOS:000188668300014 (287) - scopus: 2-s2.0-1642602694 (306)

11573/255490 - 2003 - Protection by herpes simplex virus glycoprotein D against Fas-mediated apoptosis: role of nuclear factor kappaB.
M. A., Medici; M. T., Sciortino; D., Perri; C., Amici; E., Avitabile; M., Ciotti; E., Balestrieri; De Smaele, Enrico; G., Franzoso; A., Mastino - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 36059-36067 - issn: 0021-9258 - wos: WOS:000185318300025 (84) - scopus: 2-s2.0-0141704330 (92)

11573/146716 - 2003 - Gadd45 beta mediates the protective effects of CD40 costimulation against Fas-induced apoptosis
Zazzeroni, F; Papa, S; Algeciras Schimnich, A; Alvarez, K; Melis, T; Bubici, C; Majewski, N; Hay, N; De Smaele, Enrico; Peter, Me; Franzoso, G. - 01a Articolo in rivista
rivista: BLOOD (New York: Elsevier Inc. [Washington DC etc.]: American Society of Hematology) pp. 3270-3279 - issn: 0006-4971 - wos: WOS:000186149400036 (75) - scopus: 2-s2.0-0142152436 (80)

11573/146451 - 2003 - Cell signalling (communication arising) - Cell survival and a Gadd45-factor deficiency - Reply
Zazzeroni, F; Papa, S; De Smaele, Enrico; Franzoso, G. - 01a Articolo in rivista
rivista: NATURE (London: Nature Pubihing. Group-Springer Nature Limited -London : Macmillan, 1869- -New York, NY; Nature America Incorporated) pp. 742-742 - issn: 0028-0836 - wos: WOS:000184733900029 (8) - scopus: 2-s2.0-0041466007 (7)

11573/145366 - 2002 - c-FLIP efficiently rescues TRAF-2(-/-) cells from TNF-induced apoptosis
Guiet, C; Silvestri, E; De Smaele, Enrico; Franzoso, G; Vito, P. - 01a Articolo in rivista
rivista: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 138-144 - issn: 1350-9047 - wos: WOS:000173620100008 (30) - scopus: 2-s2.0-85047696993 (31)

11573/145363 - 2002 - Regulation of the gadd45β promoter by NF-kB
Jin, R; De Smaele, Enrico; Zazzeroni, F; Nguyen D., U; Papa, S; Jones, J; Cox, C; Gelinas, C; And Franzoso, G. - 01a Articolo in rivista
rivista: DNA AND CELL BIOLOGY (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 491-503 - issn: 1044-5498 - wos: WOS:000176825900001 (62) - scopus: 2-s2.0-0035983901 (69)

11573/145360 - 2001 - Induction of gadd45β by NF-kB down-regulates pro-apoptotic JNK signaling
De Smaele, Enrico; Zazzeroni, F; Papa, S; Nguyen D., U; Jin, R; Jones, J; Cong, R; And Franzoso, G. - 01a Articolo in rivista
rivista: NATURE (London: Nature Pubihing. Group-Springer Nature Limited -London : Macmillan, 1869- -New York, NY; Nature America Incorporated) pp. 308-313 - issn: 0028-0836 - wos: WOS:000172150700044 (635) - scopus: 2-s2.0-0035889252 (680)

11573/146453 - 1999 - Identification of nuclei from apoptotic, necrotic, and viable lymphoid cells by using multiparameter flow cytometry
Matteucci, C; Grelli, S; De Smaele, Enrico; Fontana, C; Mastino, A. - 01a Articolo in rivista
rivista: CYTOMETRY (Society for Analytical Cytology:60 Revere Drive, Suite 500:Northbrook, IL 60062:(847)480-0899, EMAIL: isac@sherwood-group.com, INTERNET: http://www.isac-net.org, Fax: (847)480-9282) pp. 145-153 - issn: 0196-4763 - wos: WOS:000078231200006 (60) - scopus: 2-s2.0-0033080812 (63)

11573/189685 - 1997 - Identificazione di cellule infettate da virus influenzale mediante citometria a flusso
Grelli, S.; De Smaele, Enrico; Matteucci, C.; Osman, N.; Savini, P.; Palamara, Anna Teresa; Garaci, E.; Mastino, A. - 04a Atto di comunicazione a congresso
libro: 26° Congresso Nazionale della Società italiana di Microbiologia - ()

11573/145628 - 1997 - Immunological events during the early phase of infection with Schistosoma mansoni in mice
S., Grelli; C., Matteucci; D., Cioli; L. H., El Sayed; N., Adam; H., Ghoneim; De Smaele, Enrico; C., Favalli; E., Garaci; A., Mastino - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY (- London : SAGE Publications Ltd - Chieti : Biomedical Research Press, 1988-) pp. 205-211 - issn: 0394-6320 - wos: WOS:000071163800006 (2) - scopus: 2-s2.0-13144275276 (1)

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