DANTE ROTILI

Professore associato


email: dante.rotili@uniroma1.it
telefono: 3332749347
edificio: CU019
stanza: 206

INFORMAZIONI PERSONALI
Nome/cognome: Dante Rotili
EDUCAZIONE E FORMAZIONE
4 Giugno 2007, Dottorato (PhD) di ricerca in Scienze Farmaceutiche, Università di Roma “La Sapienza”
19 Marzo 2003, Laurea cum laude in Chimica e Tecnologia Farmaceutiche, Università di Roma “La Sapienza”
ESPERIENZA DI RICERCA
Nel settembre 2020 il Dr. Rotili ha preso servizio in qualità di Professore Associato di Chimica Farmaceutica presso il Dipartimento di Chimica e Tecnologie del Farmaco della Facoltà di Farmacia e Medicina dell’Università degli Studi di Roma “La Sapienza”.
Nel luglio 2017 il Dr. Rotili ha conseguito l'abilitazione scientifica nazionale (ASN) alle funzioni di Professore di I Fascia per il settore concorsuale 03/D1 (settore scientifico-disciplinare CHIM/08-Chimica Farmaceutica).
Dall’1 Dicembre 2011 il Dr. Rotili è Ricercatore presso il Dipartimento di Chimica e Tecnologie del Farmaco dell’Università di Roma “La Sapienza”. Dal 6 Settembre 2010 al 30 Novembre 2011 il Dr. Rotili ha lavorato come Associato di Ricerca presso il Dipartimento di Chimica e Tecnologie del Farmaco dell’Università di Roma “La Sapienza”. Dall’1 Aprile 2009 al 5 Settembre 2010 il Dr. Rotili ha lavorato come Associato di Ricerca presso il Dipartimento di Chimica dell’Università di Oxford. Dall’1 Gennaio 2007 al 31 Marzo 2009 il Dr. Rotili ha lavorato come Post-doc presso il Dipartimento di Studi Farmaceutici dell’Università di Roma “La Sapienza”.
INTERESSI DI RICERCA
Dal 2003 l’attività di ricerca del Prof. Rotili si è focalizzata prevalentemente sulla progettazione e sintesi di modulatori di enzimi epigenetici (istone acetiltransferasi/deacetilasi, metiltransferasi/demetilasi e DNA e RNA metiltransferasi/demetilasi). Un altro campo di ricerca è stato lo sviluppo di inibitori della trascrittasi inversa umana e del virus HIV-1, di inibitori delle PARP, della anidrasi carbonica e della glutatione S-transferasi. Dal 2009 il Prof. Rotili è anche coinvolto nello sviluppo di sonde chemoproteomiche per la caratterizzazione funzionale di vari target epigenetici. Infine, dal 2015 il Prof. Rotili è anche coinvolto nello sviluppo di traccianti radioattivi per la chirurgia radio-guidata dei tumori e di enhancers boronati e fluorurati di protonterapia e Boron Neutron Capture Therapy (BNCT). Dal 2022 il Prof. Rotili si occupa delle applicazioni della spettrometria di massa nativa allo studio delle interazioni proteina-proteina, proteina-acido nucleico e proteina-ligando.
PRODUZIONE SCIENTIFICA
Il Prof. Rotili è autore di oltre 160 articoli scientifici, più di 50 comunicazioni poster ed oltre 10 comunicazioni orali in congressi nazionali e internazionali.
PREMI
1) Bentham Travel Grant per il “XX Simposio Internazionale in Chimica Farmaceutica (EFMC-ISMC 2008)”; 2) Premio Farmindustria 2011 per l’eccellenza in Chimica Farmaceutica; 3) Premio “Sapienza Ricerca 2011” per ricercatori Under 40.
PARAMETRI BIBLIOMETRICI
Scopus, aggiornato al 14 Gennaio 2024: H-index: 44; Citazioni totali: 5987.
Google Scholar, aggiornato al 14 Gennaio 2024: H-index: 51; Citazioni totali: 7715.


Produzione scientifica

11573/1716808 - 2024 - Transmission-Blocking Strategies for Malaria Eradication: Recent Advances in Small-Molecule Drug Development
Appetecchia, Federico; Fabbrizi, Emanuele; Fiorentino, Francesco; Consalvi, Sara; Biava, Mariangela; Poce, Giovanna; Rotili, Dante - 01g Articolo di rassegna (Review)
rivista: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. - - issn: 1424-8247 - wos: (0) - scopus: (0)

11573/1696800 - 2024 - Enhancing sensitivity of triple-negative breast cancer to DNA-damaging therapy through chemical inhibition of the m6A methyltransferase METTL3
Cesaro, Bianca; Iaiza, Alessia; Piscopo, Fabio; Tarullo, Marco; Cesari, Eleonora; Rotili, Dante; Mai, Antonello; Diana, Alberto; Londero, Michela; Del Giacco, Luca; Masetti, Riccardo; Di Leone, Alba; Naro, Chiara; Masciarelli, Silvia; Fontemaggi, Giulia; Sette, Claudio; Fazi, Francesco; Fatica, Alessandro - 01f Lettera, Nota
rivista: CANCER COMMUNICATIONS (London: BioMed Central) pp. 282-286 - issn: 2523-3548 - wos: WOS:001125441200001 (4) - scopus: 2-s2.0-85179653539 (3)

11573/1712923 - 2024 - M6A reduction relieves FUS-associated ALS granules
Di Timoteo, Gaia; Giuliani, Andrea; Setti, Adriano; Biagi, Martina C.; Lisi, Michela; Santini, Tiziana; Grandioso, Alessia; Mariani, Davide; Castagnetti, Francesco; Perego, Eleonora; Zappone, Sabrina; Lattante, Serena; Sabatelli, Mario; Rotili, Dante; Vicidomini, Giuseppe; Bozzoni, Irene - 01a Articolo in rivista
rivista: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. - - issn: 2041-1723 - wos: (0) - scopus: 2-s2.0-85195950842 (0)

11573/1710159 - 2024 - Uracil- and Pyridine-containing HDAC inhibitors displayed cytotoxicity in colorectal and glioblastoma cancer stem cells
Fiorentino, Francesco; Fabbrizi, Emanuele; Raucci, Alessia; Noce, Beatrice; Fioravanti, Rossella; Valente, Sergio; Paolini, Chantal; De Maria, Ruggero; Steinkühler, Christian; Gallinari, Paola; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. - - issn: 1860-7187 - wos: WOS:001214621100001 (0) - scopus: 2-s2.0-85191719139 (1)

11573/1711772 - 2024 - (Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling
Golovina, Anastasia; Proia, Eleonora; Fiorentino, Francesco; Yunin, Maxim; Kasatkina, Maria; Zigangirova, Nailya; Soloveva, Anna; Sysolyatina, Elena; Ermolaeva, Svetlana; Novikov, Roman; Silonov, Sergei; Pushkin, Sergei; Mladenović, Milan; Isakova, Julia; Belik, Albina; Nawrozkij, Maxim; Rotili, Dante; Ragno, Rino; Ivanov, Roman - 01a Articolo in rivista
rivista: ACS INFECTIOUS DISEASES (Washington, DC : American Chemical Society, 2015-) pp. 2127-2150 - issn: 2373-8227 - wos: WOS:001228938600001 (0) - scopus: 2-s2.0-85194084452 (0)

11573/1710806 - 2024 - The α-tubulin acetyltransferase ATAT1: structure, cellular functions, and its emerging role in human diseases
Iuzzolino, Angela; Pellegrini, Francesca Romana; Rotili, Dante; Degrassi, Francesca; Trisciuoglio, Daniela - 01g Articolo di rassegna (Review)
rivista: CELLULAR AND MOLECULAR LIFE SCIENCES (Basel: Birkhäuser 1997-) pp. - - issn: 1420-9071 - wos: WOS:001207262200003 (1) - scopus: 2-s2.0-85191030912 (1)

11573/1710803 - 2024 - A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection
Maure, Alexandra; Lawarée, Emeline; Fiorentino, Francesco; Pawlik, Alexandre; Gona, Saideep; Giraud-Gatineau, Alexandre; Eldridge, Matthew J. G.; Danckaert, Anne; Hardy, David; Frigui, Wafa; Keck, Camille; Gutierrez, Claude; Neyrolles, Olivier; Aulner, Nathalie; Mai, Antonello; Hamon, Mélanie; Barreiro, Luis B.; Brodin, Priscille; Brosch, Roland; Rotili, Dante; Tailleux, Ludovic - 01a Articolo in rivista
rivista: PLOS BIOLOGY (San Francisco, CA : Public Library of Science, c2003-) pp. - - issn: 1545-7885 - wos: WOS:001214097100008 (0) - scopus: 2-s2.0-85191815044 (0)

11573/1703580 - 2024 - Specific inhibitors of mitochondrial deacylase sirtuin 4 endowed with cellular activity
Pannek, M.; Alhalabi, Z.; Tomaselli, D.; Menna, M.; Fiorentino, F.; Robaa, D.; Weyand, M.; Puhlmann, M.; Tomassi, S.; Barreca, F.; Tafani, M.; Zaganjor, E.; Haigis, M. C.; Sippl, W.; Rotili, D.; Mai, A.; Steegborn, C. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 1843-1860 - issn: 1520-4804 - wos: WOS:001160605300001 (3) - scopus: 2-s2.0-85184667987 (3)

11573/1703586 - 2024 - Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer
Pecci, Valeria; Troisi, Fabiola; Aiello, Aurora; De Martino, Sara; Carlino, Angela; Fiorentino, Vincenzo; Ripoli, Cristian; Rotili, Dante; Pierconti, Francesco; Martini, Maurizio; Porru, Manuela; Pinto, Francesco; Mai, Antonello; Bassi, Pier Francesco; Grassi, Claudio; Gaetano, Carlo; Pontecorvi, Alfredo; Strigari, Lidia; Farsetti, Antonella; Nanni, Simona - 01a Articolo in rivista
rivista: CANCER CELL INTERNATIONAL ([London]: BioMed Central.) pp. - - issn: 1475-2867 - wos: WOS:001156914300001 (0) - scopus: 2-s2.0-85184414355 (0)

11573/1714195 - 2024 - Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1
Spizzichino, Sharon; Di Fonzo, Federica; Marabelli, Chiara; Tramonti, Angela; Chaves-Sanjuan, Antonio; Parroni, Alessia; Boumis, Giovanna; Liberati, Francesca Romana; Paone, Alessio; Montemiglio, Linda Celeste; Ardini, Matteo; Jakobi, Arjen J.; Bharadwaj, Alok; Swuec, Paolo; Tartaglia, Gian Gaetano; Paiardini, Alessandro; Contestabile, Roberto; Mai, Antonello; Rotili, Dante; Fiorentino, Francesco; Macone, Alberto; Giorgi, Alessandra; Tria, Giancarlo; Rinaldo, Serena; Bolognesi, Martino; Giardina, Giorgio; Cutruzzola, Francesca - 01a Articolo in rivista
rivista: MOLECULAR CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. - - issn: 1097-2765 - wos: (0) - scopus: (0)

11573/1661959 - 2023 - Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells
Ansari, Mohammad Salik Zeya; Stagni, Venturina; Iuzzolino, Angela; Rotili, Dante; Mai, Antonello; Del Bufalo, Donatella; Lavia, Patrizia; Degrassi, Francesca; Trisciuoglio, Daniela - 01a Articolo in rivista
rivista: CANCER GENE THERAPY (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 124-136 - issn: 0929-1903 - wos: WOS:000854955000001 (9) - scopus: 2-s2.0-85138300847 (9)

11573/1673946 - 2023 - Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery
Aventaggiato, Michele; Barreca, Federica; Vitiello, Laura; Vespa, Simone; Valente, Sergio; Rotili, Dante; Mai, Antonello; Lotti, Lavinia Vittoria; Sansone, Luigi; Russo, Matteo A.; Bizzarri, Mariano; Ferretti, Elisabetta; Tafani, Marco - 01a Articolo in rivista
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000947513100001 (2) - scopus: 2-s2.0-85149752388 (4)

11573/1694442 - 2023 - Hydroxamate-based compounds are potent inhibitors of Toxoplasma gondii HDAC biological activity
Boissavy, Tom; Rotili, Dante; Mouveaux, Thomas; Roger, Emmanuel; Aliouat, El Moukthar; Pierrot, Christine; Valente, Sergio; Mai, Antonello; Gissot, Mathieu - 01a Articolo in rivista
rivista: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (American Society for Microbiology:PO Box 11127:Birmingham, AL 35201:(800)633-4931, (205)995-1567, EMAIL: asm.nonmembers.subs@ebsco.com, INTERNET: http://www.asm.org, Fax: (205)995-1588) pp. e0066123- - issn: 0066-4804 - wos: WOS:001090003100001 (2) - scopus: (0)

11573/1674091 - 2023 - GreenMedChem- the challenge in the next decade toward eco-friendly compounds and processes in drug design
Castiello, Carola; Junghanns, Pierre; Mergel, Annika; Jacob, Claus; Ducho, Christian; Valente, Sergio; Rotili, Dante; Fioravanti, Rossella; Zwergel, Clemens; Mai, Antonello - 01g Articolo di rassegna (Review)
rivista: GREEN CHEMISTRY (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 2109-2169 - issn: 1463-9262 - wos: WOS:000946579600001 (23) - scopus: 2-s2.0-85150432512 (31)

11573/1677023 - 2023 - Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection
Fabbrizi, Emanuele; Fiorentino, Francesco; Carafa, Vincenzo; Altucci, Lucia; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 852- - issn: 2073-4409 - wos: WOS:000957394600001 (8) - scopus: 2-s2.0-85151108488 (15)

11573/1669898 - 2023 - Pyrimidine thioethers: A novel class of antidepressant agents, endowed with anxiolytic, performance enhancing and nootropic activity
Fioravanti, Rossella; Proia, Eleonora; Tyurenkov, Ivan N; Kurkin, Denis V; Bakulin, Dmitry A; Kovalev, Nikolay S; Sheikin, Dmitry S; Kirillov, Ivan A; Nawrozkij, Maxim B; Vernigora, Andrey A; Brunilina, Leila L; Fiorentino, Francesco; Mladenović, Milan; Rotili, Dante; Ragno, Rino - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ([Paris] : Elsevier, [198?]-) pp. 114902- - issn: 1768-3254 - wos: WOS:000993134500001 (0) - scopus: 2-s2.0-85141941686 (3)

11573/1694364 - 2023 - State of the art of carbonic anhydrase activators
Fiorentino, Francesco; Carta, Fabrizio; Rotili, Dante; Mai, Antonello; Supuran, Claudiu T - 01m Editorial/Introduzione in rivista
rivista: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 2025-2028 - issn: 1756-8919 - wos: WOS:001081530900001 (3) - scopus: 2-s2.0-85177103741 (2)

11573/1689870 - 2023 - The role of structural biology in the design of sirtuin activators
Fiorentino, Francesco; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
rivista: CURRENT OPINION IN STRUCTURAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 102666- - issn: 0959-440X - wos: WOS:001057837700001 (4) - scopus: 2-s2.0-85169440750 (5)

11573/1669899 - 2023 - METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey
Fiorentino, Francesco; Menna, Martina; Rotili, Dante; Valente, Sergio; Mai, Antonello - 01g Articolo di rassegna (Review)
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 1654-1677 - issn: 1520-4804 - wos: WOS:000932489700001 (24) - scopus: 2-s2.0-85147012551 (31)

11573/1677022 - 2023 - Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII
Fiorentino, Francesco; Nocentini, Alessio; Rotili, Dante; Supuran, Claudiu T; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 2188147- - issn: 1475-6366 - wos: WOS:000949495200001 (4) - scopus: 2-s2.0-85150225921 (3)

11573/1677024 - 2023 - Native mass spectrometry-directed drug discovery: Recent advances in investigating protein function and modulation
Fiorentino, Francesco; Rotili, Dante; Mai, Antonello - 01g Articolo di rassegna (Review)
rivista: DRUG DISCOVERY TODAY (Elsevier Science Limited Trends Journals:PO Box 331, Haywards Heath RH16 3FG United Kingdom:011 44 1444 475651, EMAIL: ct.subs@rbi.co.uk, Fax: 011 44 1444 445423) pp. 103548- - issn: 1359-6446 - wos: WOS:000955583400001 (4) - scopus: 2-s2.0-85150033652 (7)

11573/1681512 - 2023 - First-in-class selective inhibitors of the lysine acetyltransferase KAT8
Fiorentino, Francesco; Sementilli, Sara; Menna, Martina; Turrisi, Federica; Tomassi, Stefano; Pellegrini, Francesca Romana; Iuzzolino, Angela; D'acunzo, Francesca; Feoli, Alessandra; Wapenaar, Hannah; Taraglio, Sophie; Fraschetti, Caterina; Del Bufalo, Donatella; Sbardella, Gianluca; Dekker, Frank J.; Paiardini, Alessandro; Trisciuoglio, Daniela; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 6591-6616 - issn: 1520-4804 - wos: WOS:000988858800001 (2) - scopus: 2-s2.0-85159627845 (3)

11573/1695097 - 2023 - BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress
Marchant, Vanessa; Trionfetti, Flavia; Tejedor-Santamaria, Lucia; Rayego-Mateos, Sandra; Rotili, Dante; Bontempi, Giulio; Domenici, Alessandro; Menè, Paolo; Mai, Antonello; Martín-Cleary, Catalina; Ortiz, Alberto; Ramos, Adrian M.; Strippoli, Raffaele; Ruiz-Ortega, Marta - 01a Articolo in rivista
rivista: ANTIOXIDANTS (Basel: MDPI) pp. 1-19 - issn: 2076-3921 - wos: WOS:001137851500001 (0) - scopus: 2-s2.0-85180466019 (0)

11573/1669922 - 2023 - Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells
Negri, Aide; Marozzi, Marina; Trisciuoglio, Daniela; Rotili, Dante; Mai, Antonello; Rizzi, Federica - 01a Articolo in rivista
rivista: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Abingdon Oxfordshire United Kingdom: Taylor & Francis London: Gordon and Breach, 2002-) pp. 2163242- - issn: 1475-6374 - wos: WOS:000911853100001 (5) - scopus: 2-s2.0-85146193316 (8)

11573/1658358 - 2023 - Chemically diverse S. mansoni HDAC8 inhibitors reduced viability in worm larval and adult stages
Noce, Beatrice; Di Bello, Elisabetta; Zwergel, Clemens; Fioravanti, Rossella; Valente, Sergio; Rotili, Dante; Masotti, Andrea; Ansari, Mohammad Salik Zeya; Trisciuoglio, Daniela; Chakrabarti, Alokta; Romier, Christophe; Robaa, Dina; Sippl, Wolfgang; Jung, Manfred; Häberli, Cécile; Keiser, Jennifer; Mai, Antonello - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. - - issn: 1860-7179 - wos: WOS:000879912800001 (6) - scopus: 2-s2.0-85141693563 (7)

11573/1689849 - 2023 - Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa.
Scribani Rossi, C; Eckartt, K; Scarchilli, E; Angeli, S; Price-Whelan, A; Di Matteo, A; Chevreuil, M; Raynal, B; Arcovito, A; Giacon, N; Fiorentino, F; Rotili, D; Mai, A; Espinosa-Urgel, M; Cutruzzola', F; Dietrich, Lep; Paone, A; Paiardini, A; Rinaldo, S - 01a Articolo in rivista
rivista: MICROBIOLOGICAL RESEARCH (Urban & Fischer Verlag Jena:Postfach 100537, D-07705 Jena Germany:011 49 3641 626430, EMAIL: journals@urbanfischer.de, INTERNET: http://www.urbanfischer.de, Fax: 011 49 3641 626500) pp. 127498- - issn: 0944-5013 - wos: WOS:001097478000001 (3) - scopus: 2-s2.0-85173505521 (3)

11573/1696065 - 2023 - HDAC1-3 inhibition increases SARS-CoV-2 replication and productive infection in lung mesothelial and epithelial cells
Trionfetti, Flavia; Alonzi, Tonino; Bontempi, Giulio; Terri, Michela; Battistelli, Cecilia; Montaldo, Claudia; Repele, Federica; Rotili, Dante; Valente, Sergio; Zwergel, Clemens; Matusali, Giulia; Maggi, Fabrizio; Goletti, Delia; Tripodi, Marco; Mai, Antonello; Strippoli, Raffaele - 01a Articolo in rivista
rivista: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (Lausanne : Frontiers Media SA, 2011-) pp. - - issn: 2235-2988 - wos: WOS:001130489700001 (3) - scopus: 2-s2.0-85180885673 (3)

11573/1694558 - 2023 - SIRT6 Protects Against Lipopolysaccharide-Induced Inflammation in Human Pulmonary Lung Microvascular Endothelial Cells
Wang, Jinping; Luo, Jinque; Rotili, Dante; Mai, Antonello; Steegborn, Clemens; Xu, Suowen; Jin, Zheng Gen - 01a Articolo in rivista
rivista: INFLAMMATION (Springer Nature New York, NY: Plenum Press) pp. - - issn: 0360-3997 - wos: WOS:001082492200001 (3) - scopus: 2-s2.0-85173797364 (4)

11573/1694680 - 2023 - Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase
Zhou, Jujun; Deng, Youchao; Iyamu, Iredia D; Horton, John R; Yu, Dan; Hajian, Taraneh; Vedadi, Masoud; Rotili, Dante; Mai, Antonello; Blumenthal, Robert M; Zhang, Xing; Huang, Rong; Cheng, Xiaodong - 01a Articolo in rivista
rivista: ACS CHEMICAL BIOLOGY (Washington, D.C. : American Chemical Society, c2006-) pp. 734-745 - issn: 1554-8937 - wos: WOS:000936764500001 (2) - scopus: 2-s2.0-85148863880 (2)

11573/1664753 - 2023 - Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence
Zhou, Jujun; Horton, John R.; Menna, Martina; Fiorentino, Francesco; Ren, Ren; Yu, Dan; Hajian, Taraneh; Vedadi, Masoud; Mazzoccanti, Giulia; Ciogli, Alessia; Weinhold, Elmar; Hüben, Michael; Blumenthal, Robert M.; Zhang, Xing; Mai, Antonello; Rotili, Dante; Cheng, Xiaodong - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 934-950 - issn: 0022-2623 - wos: WOS:000907749800001 (3) - scopus: 2-s2.0-85145455635 (4)

11573/1684985 - 2023 - Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells
Zwergel, Clemens; Aventaggiato, Michele; Garbo, Sabrina; Di Bello, Elisabetta; Fassari, Bruno; Noce, Beatrice; Castiello, Carola; Lambona, Chiara; Barreca, Federica; Rotili, Dante; Fioravanti, Rossella; Schmalz, Thomas; Weyand, Michael; Niedermeier, Amelie; Tripodi, Marco; Colotti, Gianni; Steegborn, Clemens; Battistelli, Cecilia; Tafani, Marco; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9622-9641 - issn: 0022-2623 - wos: WOS:001027732800001 (8) - scopus: 2-s2.0-85165671509 (7)

11573/1658360 - 2022 - Histone lysine demethylase inhibition reprograms prostate cancer metabolism and mechanics
Chianese, Ugo; Papulino, Chiara; Passaro, Eugenia; Evers, Tom Mj; Babaei, Mehrad; Toraldo, Antonella; De Marchi, Tommaso; Niméus, Emma; Carafa, Vincenzo; Nicoletti, Maria Maddalena; Del Gaudio, Nunzio; Iaccarino, Nunzia; Randazzo, Antonio; Rotili, Dante; Mai, Antonello; Cappabianca, Salvatore; Mashaghi, Alireza; Ciardiello, Fortunato; Altucci, Lucia; Benedetti, Rosaria - 01a Articolo in rivista
rivista: MOLECULAR METABOLISM (Amsterdam : Elsevier) pp. 101561- - issn: 2212-8778 - wos: WOS:000844094200002 (3) - scopus: 2-s2.0-85136069603 (3)

11573/1618409 - 2022 - Multimodal evaluation of 19F-BPA internalization in pancreatic cancer cells for boron capture and proton therapy potential applications
Ciardiello, A.; Altierix, S.; Ballarini, F.; Bocci, V.; Bortolussi, S.; Cansolino, L.; Carlotti, D.; Ciocca, M.; Faccini, R.; Facoetti, A.; Ferrari, C.; Ficcadenti, L.; Furfaro, E.; Giagu, S.; Iacoangeli, F.; Macioce, G.; Mancini-Terracciano, C.; Messina, A.; Milazzo, L.; Pacifico, S.; Piccolella, S.; Postuma, I.; Rotili, D.; Vercesi, V.; Voena, C.; Vulcano, F.; Capuani, S. - 01a Articolo in rivista
rivista: PHYSICA MEDICA (UK: Elsevier Pisa: Istituti Editoriali e Poligrafici Internazionali. Pisa Italy: Giardini Editori Stampatori) pp. 75-84 - issn: 1120-1797 - wos: WOS:000750944300002 (4) - scopus: 2-s2.0-85122230962 (3)

11573/1650772 - 2022 - Effects of structurally different HDAC inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni
Di Bello, Elisabetta; Noce, Beatrice; Fioravanti, Rossella; Zwergel, Clemens; Valente, Sergio; Rotili, Dante; Fianco, Giulia; Trisciuoglio, Daniela; Mourão, Marina M; Sales, Policarpo; Lamotte, Suzanne; Prina, Eric; Späth, Gerald F; Häberli, Cécile; Keiser, Jennifer; Mai, Antonello - 01a Articolo in rivista
rivista: ACS INFECTIOUS DISEASES (Washington, DC : American Chemical Society, 2015-) pp. 1356-1366 - issn: 2373-8227 - wos: WOS:000819851400001 (16) - scopus: 2-s2.0-85134360722 (16)

11573/1657352 - 2022 - Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5
Fiorentino, F.; Castiello, C.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9580-9606 - issn: 0022-2623 - wos: WOS:000835071900001 (20) - scopus: 2-s2.0-85135378527 (24)

11573/1638052 - 2022 - Sirtuin modulators: past, present, and future perspectives
Fiorentino, Francesco; Mautone, Nicola; Menna, Martina; D'acunzo, Francesca; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
rivista: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. - - issn: 1756-8919 - wos: WOS:000797024400001 (0) - scopus: 2-s2.0-85131771683 (20)

11573/1628944 - 2022 - Neuroprotective effects of PARP inhibitors in Drosophila models of Alzheimer’s disease
Maggiore, Anna; Casale, Assunta Maria; Toscanelli, Walter; Cappucci, Ugo; Rotili, Dante; Grieco, Maddalena; Gagné, Jean-Philippe; Poirier, Guy G.; D’Erme, Maria; Piacentini, Lucia - 01a Articolo in rivista
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000786053000001 (10) - scopus: 2-s2.0-85127837219 (11)

11573/1635728 - 2022 - Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models
Menna, M.; Fiorentino, F.; Marrocco, B.; Lucidi, A.; Tomassi, S.; Cilli, D.; Romanenghi, M.; Cassandri, M.; Pomella, S.; Pezzella, M.; Del Bufalo, D.; Zeya Ansari, M. S.; Tomasevic, N.; Mladenovic, M.; Viviano, M.; Sbardella, G.; Rota, R.; Trisciuoglio, D.; Minucci, S.; Mattevi, A.; Rotili, D.; Mai, A. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000804176200002 (15) - scopus: 2-s2.0-85129352278 (16)

11573/1613297 - 2022 - Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription
Minisini, Martina; Di Giorgio, Eros; Kerschbamer, Emanuela; Dalla, Emiliano; Faggiani, Massimo; Franforte, Elisa; Meyer-Almes, Franz-Josef; Ragno, Rino; Antonini, Lorenzo; Mai, Antonello; Fiorentino, Francesco; Rotili, Dante; Chinellato, Monica; Perin, Stefano; Cendron, Laura; Weichenberger, Christian X; Angelini, Alessandro; Brancolini, Claudio - 01a Articolo in rivista
rivista: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. - - issn: 0305-1048 - wos: WOS:000764227300001 (13) - scopus: 2-s2.0-85127539205 (14)

11573/1622839 - 2022 - A potent HDAC inhibitor blocks Toxoplasma gondii tachyzoite growth and profoundly disrupts parasite gene expression
Mouveaux, T.; Rotili, D.; Boissavy, T.; Roger, E.; Pierrot, C.; Mai, A.; Gissot, M. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 106526- - issn: 0924-8579 - wos: WOS:000784446400008 (12) - scopus: 2-s2.0-85124124624 (11)

11573/1664310 - 2022 - Modulation of virulence-associated traits in Aspergillus fumigatus by BET Inhibitor JQ1
Orekhova, Anastasia; De Angelis, Marta; Cacciotti, Andrea; Reverberi, Massimo; Rotili, Dante; Giorgi, Alessandra; Protto, Virginia; Bonincontro, Graziana; Fiorentino, Francesco; Zgoda, Victor; Mai, Antonello; Palamara, Anna Teresa; Simonetti, Giovanna - 01a Articolo in rivista
rivista: MICROORGANISMS (Basel: MDPI) pp. 1-19 - issn: 2076-2607 - wos: WOS:000895665300001 (1) - scopus: 2-s2.0-85144917834 (2)

11573/1541295 - 2022 - 90Y-DOTA-nimotuzumab: synthesis of a promising β⁻ radiopharmaceutical
Scotognella, T.; Maccora, D.; Bruno, I.; Chinol, M.; Castagnola, M.; Collamati, F.; Mancini-Terraciano, C.; Morganti, S.; Bocci, V.; Solfaroli-Camillocci, E.; Rotili, D; Cartoni, A; Fratoddi, I; Marini, F.; Venditti, I.; Faccini, R.; Giordano, A. - 01a Articolo in rivista
rivista: CURRENT RADIOPHARMACEUTICALS (Bentham Science Publishers Ltd) pp. 32-39 - issn: 1874-4710 - wos: WOS:000808516000004 (2) - scopus: 2-s2.0-85127163927 (2)

11573/1622835 - 2022 - The Nitrobenzoxadiazole Derivative NBDHEX Behaves as Plasmodium falciparum Gametocyte Selective Inhibitor with Malaria Parasite Transmission Blocking Activity
Siciliano, G.; Di Paolo, V.; Rotili, D.; Migale, R.; Pedini, F.; Casella, M.; Camerini, S.; Dalzoppo, D.; Henderson, R.; Huijs, T.; Dechering, K. J.; Mai, A.; Caccuri, A. M.; Lalle, M.; Quintieri, L.; Alano, P. - 01a Articolo in rivista
rivista: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. 168- - issn: 1424-8247 - wos: WOS:000825152000002 (4) - scopus: 2-s2.0-85123900571 (5)

11573/1628559 - 2022 - Biochemical functions and clinical characterizations of the sirtuins in diabetes-induced retinal pathologies
Taurone, Samanta; De Ponte, Chiara; Rotili, Dante; De Santis, Elena; Mai, Antonello; Fiorentino, Francesco; Scarpa, Susanna; Artico, Marco; Micera, Alessandra - 01g Articolo di rassegna (Review)
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000782009200001 (12) - scopus: 2-s2.0-85127570606 (13)

11573/1617428 - 2022 - Hydrophilic gold nanoparticles as Anti-PD-L1 antibody carriers. Synthesis and interface properties
Venditti, I.; Cartoni, A.; Cerra, S.; Fioravanti, R.; Salamone, T. A.; Sciubba, F.; Tabocchini, M. A.; Dini, V.; Battocchio, C.; Iucci, G.; Carlini, L.; Faccini, R.; Collamati, F.; Mancini T, C.; Solfaroli C, E.; Morganti, S.; Giordano, A.; Scotognella, T.; Maccora, D.; Rotili, D.; Marchese, C.; Anastasiadou, E.; Trivedi, P.; Fratoddi, I. - 01a Articolo in rivista
rivista: PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 1-12 - issn: 0934-0866 - wos: WOS:000753440400001 (9) - scopus: 2-s2.0-85124617698 (10)

11573/1503800 - 2021 - Regulatory interplay between mir-181a-5p and estrogen receptor signaling cascade in breast cancer
Benedetti, R.; Papulino, C.; Sgueglia, G.; Chianese, U.; De Marchi, T.; Iovino, F.; Rotili, D.; Mai, A.; Nimeus, E.; Aversana, C. D.; Altucci, L. - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. 1-19 - issn: 2072-6694 - wos: WOS:000614992800001 (9) - scopus: 2-s2.0-85100578967 (11)

11573/1541036 - 2021 - The two-faced role of sirt6 in cancer
Fiorentino, F.; Carafa, V.; Favale, G.; Altucci, L.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
rivista: CANCERS (Basel: MDPI) pp. 1-26 - issn: 2072-6694 - wos: WOS:000627939700001 (34) - scopus: 2-s2.0-85102076188 (37)

11573/1585511 - 2021 - Emerging Therapeutic Potential of SIRT6 Modulators
Fiorentino, F.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9732-9758 - issn: 0022-2623 - wos: WOS:000677581000007 (39) - scopus: 2-s2.0-85110981411 (40)

11573/1585447 - 2021 - Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein-protein interactions
Fiorentino, F.; Rotili, D.; Mai, A.; Bolla, J. R.; Robinson, C. V. - 01a Articolo in rivista
rivista: CHEMICAL COMMUNICATIONS (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 10747-10750 - issn: 1359-7345 - wos: WOS:000700904000001 (9) - scopus: 2-s2.0-85117218452 (10)

11573/1585389 - 2021 - Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives
Fiorentino, Francesco; De Angelis, Marta; Menna, Martina; Rovere, Annarita; Maria Caccuri, Anna; D'acunzo, Francesca; Palamara, Anna Teresa; Nencioni, Lucia; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 2128-2138 - issn: 1475-6366 - wos: WOS:000700847900001 (5) - scopus: 2-s2.0-85116047224 (5)

11573/1611281 - 2021 - Metabolic rewiring by loss of sirt5 promotes kras-induced pancreatic cancer progression
Hu, T.; Shukla, S. K.; Vernucci, E.; He, C.; Wang, D.; King, R. J.; Jha, K.; Siddhanta, K.; Mullen, N. J.; Attri, K. S.; Murthy, D.; Chaika, N. V.; Thakur, R.; Mulder, S. E.; Pacheco, C. G.; Fu, X.; High, R. R.; Yu, F.; Lazenby, A.; Steegborn, C.; Lan, P.; Mehla, K.; Rotili, D.; Chaudhary, S.; Valente, S.; Tafani, M.; Mai, A.; Auwerx, J.; Verdin, E.; Tuveson, D.; Singh, P. K. - 01a Articolo in rivista
rivista: GASTROENTEROLOGY (USA: Elsevier Philadelphia, PA: W B Saunders Company) pp. 1584-1600 - issn: 0016-5085 - wos: WOS:000711484200002 (53) - scopus: 2-s2.0-85115084196 (61)

11573/1576703 - 2021 - Sirt5 inhibition induces brown fat-like phenotype in 3t3-l1 preadipocytes
Molinari, Francesca; Feraco, Alessandra; Mirabilii, Simone; Saladini, Serena; Sansone, Luigi; Vernucci, Enza; Tomaselli, Giada; Marzolla, Vincenzo; Rotili, Dante; A Russo, Matteo; Ricciardi, Maria Rosaria; Tafuri, Agostino; Mai, Antonello; Caprio, Massimiliano; Tafani, Marco; Armani, Andrea - 01a Articolo in rivista
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 1-17 - issn: 2073-4409 - wos: WOS:000654660100001 (18) - scopus: 2-s2.0-85107437198 (19)

11573/1601697 - 2021 - First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53
Nowak, R. P.; Tumber, A.; Hendrix, E.; Ansari, M. S. Z.; Sabatino, M.; Antonini, L.; Andrijes, R.; Salah, E.; Mautone, N.; Pellegrini, F. R.; Simelis, K.; Kawamura, A.; Johansson, C.; Passeri, D.; Pellicciari, R.; Ciogli, A.; Del Bufalo, D.; Ragno, R.; Coleman, M. L.; Trisciuoglio, D.; Mai, A.; Oppermann, U.; Schofield, C. J.; Rotili, D. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 17031-17050 - issn: 0022-2623 - wos: WOS:000754727400006 (8) - scopus: 2-s2.0-85120646873 (9)

11573/1601812 - 2021 - JQ1, inibitore delle proteine BET, riduce i fattori di virulenza e la patogenicità di Aspergillus fumigatus.
Orekhova, A.; De Angelis, M.; Protto, V.; Rotili, D.; Mai, A.; A. T., Palamara.; Simonetti, G - 04d Abstract in atti di convegno
congresso: Nome convegno (Napoli)
libro: 13° Congresso Nazionale della Società Italiana di Microbiologia Farmaceutica Obiettivi e Sfide della Microbiologia Moderna per la Difesa della Salute - ()

11573/1408683 - 2020 - The pan-sirtuin inhibitor MC2494 regulates mitochondrial function in a leukemia cell line
Carafa, Vincenzo; Russo, Rosita; Della Torre, Laura; Cuomo, Francesca; Dell'aversana, Carmela; Sarno, Federica; Sgueglia, Giulia; Di Donato, Marzia; Rotili, Dante; Mai, Antonello; Nebbioso, Angela; Cobellis, Gilda; Chambery, Angela; Altucci, Lucia - 01a Articolo in rivista
rivista: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. - - issn: 2234-943X - wos: WOS:000539644000001 (8) - scopus: 2-s2.0-85085984851 (9)

11573/1434640 - 2020 - CDK9 as a valuable target in cancer: from natural compounds inhibitors to current treatment in pediatric soft tissue sarcomas
Cassandri, Matteo; Fioravanti, Rossella; Pomella, Silvia; Valente, Sergio; Rotili, Dante; Del Baldo, Giada; De Angelis, Biagio; Rota, Rossella; Mai, Antonello - 01a Articolo in rivista
rivista: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000565986100001 (22) - scopus: 2-s2.0-85089884656 (27)

11573/1387842 - 2020 - Radioguided surgery with β− radiation in pancreatic Neuroendocrine tumors: a feasibility study
Collamati, F.; Maccora, D.; Alfieri, S.; Bocci, V; Cartoni, A.; Collarino, A.; De Simoni, M.; Fischetti, M.; Fratoddi, I.; Giordano, A.; Mancini-Terracciano, C.; Mirabelli, R.; Morganti, S.; Quero, G.; Rotili, D.; Scotognella, T.; Solfaroli Camillocci, E.; Traini, G.; Venditti, I.; Faccini, R. - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 1-10 - issn: 2045-2322 - wos: WOS:000563275200010 (6) - scopus: 2-s2.0-85080868854 (7)

11573/1429750 - 2020 - Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni
Coutinho Carneiro, V.; De Abreu Da Silva, I. C.; Amaral, M. S.; Pereira, A. S. A.; Silveira, G. O.; Pires, D. D. S.; Verjovski-Almeida, S.; Dekker, F. J.; Rotili, D.; Mai, A.; Lopes-Torres, E. J.; Robaa, D.; Sippl, W.; Pierce, R. J.; Borrello, M. T.; Ganesan, A.; Lancelot, J.; Thiengo, S.; Fernandez, M. A.; Vicentino, A. R. R.; Mourao, M. M.; Coelho, F. S.; Fantappie, M. R. - 01a Articolo in rivista
rivista: PLOS NEGLECTED TROPICAL DISEASES (San Francisco, CA : Public Library of Science) pp. - - issn: 1935-2735 - wos: WOS:000547527200003 (6) - scopus: 2-s2.0-85087471659 (7)

11573/1429748 - 2020 - Characterization of water-soluble esters of nitrobenzoxadiazole-based GSTP1-1 inhibitors for cancer treatment
Di Paolo, V.; Fulci, C.; Rotili, D.; De Luca, A.; Tomassi, S.; Serra, M.; Scimeca, M.; Geroni, C.; Quintieri, L.; Caccuri, A. M. - 01a Articolo in rivista
rivista: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited -London ; New York : Pergamon Press, 1958-) pp. 114060- - issn: 0006-2952 - wos: WOS:000551658300022 (7) - scopus: 2-s2.0-85086125526 (8)

11573/1382315 - 2020 - Tranylcypromine-based LSD1 inhibitors: structure-activity relationships, antiproliferative effects in leukemia, and gene target modulation
Fioravanti, R.; Romanelli, A.; Mautone, N.; Di Bello, E.; Rovere, A.; Corinti, D.; Zwergel, C.; Valente, S.; Rotili, D.; Botrugno, O. A.; Dessanti, P.; Vultaggio, S.; Vianello, P.; Cappa, A.; Binda, C.; Mattevi, A.; Minucci, S.; Mercurio, C.; Varasi, M.; Mai, A. - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 643-658 - issn: 1860-7179 - wos: WOS:000513271600001 (19) - scopus: 2-s2.0-85079446800 (21)

11573/1425034 - 2020 - Targeting histone acetylation/deacetylation in parasites: an update (2017–2020)
Fioravanti, Rossella; Mautone, Nicola; Rovere, Annarita; Rotili, Dante; Mai, Antonello - 01g Articolo di rassegna (Review)
rivista: CURRENT OPINION IN CHEMICAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 65-74 - issn: 1367-5931 - wos: WOS:000568781700011 (38) - scopus: 2-s2.0-85086940284 (41)

11573/1585515 - 2020 - Lysine acetyltransferase inhibitors from natural sources
Fiorentino, F.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
rivista: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. 1-15 - issn: 1663-9812 - wos: WOS:000565346900001 (21) - scopus: 2-s2.0-85089907540 (25)

11573/1585513 - 2020 - HAT inhibitors in cancer therapy
Fiorentino, Francesco; Mai, Antonello; Rotili, Dante - 02a Capitolo o Articolo
libro: Histone Modifications in Therapy - (9780128164228)

11573/1401342 - 2020 - Identification of Inhibitors to trypanosoma cruzi sirtuins based on compounds developed to human enzymes
Matutino Bastos, Tanira; Botelho Pereira Soares, Milena; Haddad Franco, Caio; Alcântara, Laura; Antonini, Lorenzo; Sabatino, Manuela; Mautone, Nicola; Holanda Freitas-Junior, Lucio; Moraes, Carolina Borsoi; Ragno, Rino; Rotili, Dante; Schenkman, Sergio; Mai, Antonello; Silvio Moretti, Nilmar - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000539312100255 (9) - scopus: 2-s2.0-85085293622 (10)

11573/1384850 - 2020 - Sirtuin modulators: where are we now? A review of patents from 2015 to 2019
Mautone, Nicola; Zwergel, Clemens; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
rivista: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. - - issn: 1354-3776 - wos: WOS:000526337100001 (40) - scopus: 2-s2.0-85083571564 (42)

11573/1480930 - 2020 - Recent advances in epigenetic proteolysis targeting chimeras (Epi-PROTACs)
Tomaselli, D.; Mautone, N.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000591227400031 (14) - scopus: 2-s2.0-85089918812 (15)

11573/1408685 - 2020 - Sirt4: a multifaceted enzyme at the crossroads of mitochondrial metabolism and cancer
Tomaselli, D.; Steegborn, C.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
rivista: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. - - issn: 2234-943X - wos: WOS:000531334700001 (47) - scopus: 2-s2.0-85083986337 (50)

11573/1389775 - 2020 - From PARP1 to TNKS2 inhibition: A structure-based approach
Tomassi, Stefano; Pfahler, Julian; Mautone, Nicola; Rovere, Annarita; Esposito, Chiara; Passeri, Daniela; Pellicciari, Roberto; Novellino, Ettore; Pannek, Martin; Steegborn, Clemens; Paiardini, Alessandro; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
rivista: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. - - issn: 1948-5875 - wos: WOS:000535281200039 (8) - scopus: 2-s2.0-85087107488 (8)

11573/1355613 - 2019 - H19-dependent transcriptional regulation of β3 and β4 integrins upon estrogen and hypoxia favors metastatic potential in prostate cancer
Bacci, L.; Aiello, A.; Ripoli, C.; Loria, R.; Pugliese, D.; Pierconti, F.; Rotili, D.; Strigari, L.; Pinto, F.; Bassi, P. F.; Mai, A.; Grassi, C.; Pontecorvi, A.; Falcioni, R.; Farsetti, A.; Nanni, S. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000484411100169 (22) - scopus: 2-s2.0-85071378179 (21)

11573/1355598 - 2019 - Inhibition of histone demethylases LSD1 and UTX regulates ERα signaling in breast cancer
Benedetti, R.; Dell'aversana, C.; De Marchi, T.; Rotili, D.; Liu, N. Q.; Novakovic, B.; Boccella, S.; Di Maro, S.; Cosconati, S.; Baldi, A.; Nimeus, E.; Schultz, J.; Hoglund, U.; Maione, S.; Papulino, C.; Chianese, U.; Iovino, F.; Federico, A.; Mai, A.; Stunnenberg, H. G.; Nebbioso, A.; Altucci, L. - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000507382100204 (34) - scopus: 2-s2.0-85077269849 (36)

11573/1193778 - 2019 - Identification of novel quinazoline derivatives as potent antiplasmodial agents
Bouchut, A; Rotili, D; Pierrot, C; Valente, S; Lafitte, S; Schultz, J; Hoglund, U; Mazzone, R; Lucidi, A; Fabrizi, G; Pechalrieu, D; Arimondo, Pb; Skinner-Adams, Ts; Chua, Mj; Andrews, Kt; Mai, A; Khalife, J. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 277-291 - issn: 0223-5234 - wos: WOS:000451498200018 (46) - scopus: 2-s2.0-85055197167 (48)

11573/1336693 - 2019 - Enzymatic and biological characterization of novel sirtuin modulators against cancer
Carafa, V.; Poziello, A.; Torre, L. D.; Giovannelli, P.; Di Donato, M.; Safadeh, E.; Yu, Z.; Baldi, A.; Castoria, G.; Tomaselli, D.; Mai, A.; Rotili, D.; Nebbioso, A.; Altucci, L. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000502786800136 (11) - scopus: 2-s2.0-85074828780 (13)

11573/1355615 - 2019 - Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis
Di Paolo, V.; Fulci, C.; Rotili, D.; Sciarretta, F.; Lucidi, A.; Morozzo Della Rocca, B.; De Luca, A.; Rosato, A.; Quintieri, L.; Caccuri, A. M. - 01a Articolo in rivista
rivista: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 1131-1139 - issn: 1475-6366 - wos: WOS:000476871200001 (7) - scopus: 2-s2.0-85067475804 (8)

11573/1336760 - 2019 - DNA Methylation: Biological Implications and Modulation of Its Aberrant Dysregulation
Lucidi, Alessia; Tomaselli, Daniela; Rotili, Dante; Mai, Antonello - 02a Capitolo o Articolo
libro: The DNA, RNA, and Histone Methylomes - (978-3-030-14791-4; 978-3-030-14792-1)

11573/1306441 - 2019 - Gold nanoparticles and nanorods in nuclear medicine: a mini review
Maccora, Daria; Dini, Valentina; Battocchio, Chiara; Fratoddi, Ilaria; Cartoni, Antonella; Rotili, Dante; Castagnola, Massimo; Faccini, Riccardo; Bruno, Isabella; Scotognella, Teresa; Giordano, Alessandro; Venditti, Iole - 01g Articolo di rassegna (Review)
rivista: APPLIED SCIENCES (Basel: MDPI AG, 2011-) pp. - - issn: 2076-3417 - wos: WOS:000484444100026 (44) - scopus: 2-s2.0-85071043073 (49)

11573/1336715 - 2019 - Structure-reactivity relationships on substrates and inhibitors of the lysine deacylase sirtuin 2 from schistosoma mansoni (SmSirt2)
Monaldi, Daria; Rotili, Dante; Julien Lancelot, ‡; Martin Marek, §; Nathalie Wössner, ∥; Lucidi, Alessia; Tomaselli, Daniela; Elizabeth Ramos-Morales, ‡; Christophe Romier, ∥; Pierce, ∥ Raymond J.; Mai, Antonello; And Manfred Jung, ‡ - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8733-8759 - issn: 0022-2623 - wos: WOS:000490355000005 (20) - scopus: 2-s2.0-85072924967 (19)

11573/1221842 - 2019 - Effect of α-methoxy substitution on the anti-HIV activity of dihydropyrimidin-4(3 H)-ones
Nawrozkij, Maxim B.; Forgione, Mariantonietta; Yablokov, Alexandre S.; Lucidi, Alessia; Tomaselli, Daniela; Patsilinakos, Alexandros; Panella, Cristina; Hailu, Gebremedhin S.; Kirillov, Ivan A.; Badia, Roger; Riveira-Munoz, Eva; Crespan, Emmanuele; Armijos Rivera, Jorge I.; Cirilli, Roberto; Ragno, Rino; Esté, José A.; Maga, Giovanni; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 604-621 - issn: 0022-2623 - wos: WOS:000457067600015 (14) - scopus: 2-s2.0-85059424455 (12)

11573/1336742 - 2019 - α,γ-Diketocarboxylic acids and their esters act as carbonic anhydrase IX and XII selective inhibitors
Nocentini, Alessio; Lucidi, Alessia; Perut, Francesca; Massa, Annamaria; Tomaselli, Daniela; Gratteri, Paola; Baldini, Nicola; Rotili, Dante; Mai, Antonello; Supuran, Claudiu T. - 01a Articolo in rivista
rivista: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 661-665 - issn: 1948-5875 - wos: WOS:000464767700047 (18) - scopus: 2-s2.0-85064255109 (19)

11573/1339733 - 2019 - Epigenetic modulators as a new strategies to reduce Aspergillus pathogenicity
Orekhova, Anastasia; D’Auria, F. D.; Rotili, D.; Mai, A.; Palamara, A. T.; Simonetti, G - 04f Poster
congresso: 47° Congresso Nazionale della Società Italiana di Microbiologia (Roma)
libro: 47° Congresso Nazionale della Società Italiana di Microbiologia - ()

11573/1355611 - 2019 - Effects of glutathione transferase-targeting nitrobenzoxadiazole compounds in relation to PD-L1 status in human melanoma cells
Sciarretta, F.; Fulci, C.; Palumbo, C.; Rotili, D.; Tentori, L.; Graziani, G.; Caccuri, A. M. - 01a Articolo in rivista
rivista: CHEMOTHERAPY (S Karger AG:Allschwilerstrasse 10, CH-4009 Basel Switzerland:011 41 61 3061111, EMAIL: orders@karger.ch, INTERNET: http://www.karger.com, Fax: 011 41 61 3061234) pp. 138-145 - issn: 0009-3157 - wos: WOS:000501814700004 (5) - scopus: 2-s2.0-85074343924 (5)

11573/1355609 - 2019 - Comparison of the effects of synthetic and plant-derived mTOR regulators on healthy human ovarian cells
Sirotkin, A. V.; Adamcova, E.; Rotili, D.; Mai, A.; Mlyncek, M.; Mansour, L.; Alwasel, S.; Harrath, A. H. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF PHARMACOLOGY (AMSTERDAM, NETHERLANDS: ELSEVIER SCIENCE) pp. 70-78 - issn: 0014-2999 - wos: WOS:000468305200009 (1) - scopus: 2-s2.0-85063965408 (2)

11573/1336730 - 2019 - Epigenetic polypharmacology: a new frontier for epi-drug discovery
Tomaselli, Daniela; Lucidi, Alessia; Rotili, Dante; Mai, Antonello - 01g Articolo di rassegna (Review)
rivista: MEDICINAL RESEARCH REVIEWS ([New York, N.Y.] : Wiley) pp. 190-244 - issn: 1098-1128 - wos: WOS:000534635500009 (72) - scopus: 2-s2.0-85075138650 (81)

11573/1355619 - 2019 - Histone Acetyltransferase Enzymes: From Biological Implications to Most Relevant Inhibitors
Trisciuoglio, Daniela; Rotili, Dante - 02a Capitolo o Articolo
libro: Topics in medicinal chemistry - ()

11573/1355602 - 2019 - Histone deacetylase inhibitors exert anti-tumor effects on human adherent and stem-like glioma cells 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis
Was, H.; Krol, S. K.; Rotili, D.; Mai, A.; Wojtas, B.; Kaminska, B.; Maleszewska, M. - 01a Articolo in rivista
rivista: CLINICAL EPIGENETICS (Berlin : Springer) pp. 11- - issn: 1868-7083 - wos: WOS:000456005400002 (53) - scopus: 2-s2.0-85060173887 (52)

11573/1275422 - 2019 - Sirtuins as drug targets
Zwergel, Clemens; Rotili, Dante; Valente, Sergio; Mai, Antonello - 02a Capitolo o Articolo
libro: Epigenetic Drug Discovery - (9783527343140; 9783527809257)

11573/1116555 - 2018 - RIP1-HAT1-SirT complex identification and targeting in treatment and prevention of cancer
Carafa, Vincenzo; Nebbioso, Angela; Cuomo, Francesca; Rotili, Dante; Cobellis, Gilda; Bontempo, Paola; Baldi, Alfonso; Spugnini, Enrico P.; Citro, Alfonso Gennaro; Chambery, Angela; Russo, Rosita; Ciana, Paolo; Maravigna, Luca; Shaik, Jani; Radaelli, Enrico; De Antonellis, Pasquale; Tarantino, Domenico; Pirolli, Adele; Ragno, Rino; Massimo Zollo, .; Stunnenberg, Hendrik G.; Mai, Antonello; Altucci, Lucia - 01a Articolo in rivista
rivista: CLINICAL CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 2886-2900 - issn: 1078-0432 - wos: WOS:000435462700019 (35) - scopus: 2-s2.0-85052287980 (38)

11573/1115449 - 2018 - KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2
Cocco, Elisa; Leo, Manuela; Canzonetta, Claudia; Di Vito, Serena; Mai, Antonello; Rotili, Dante; Di Napoli, Arianna; Vecchione, Andrea; De Nunzio, Cosimo; Filetici, Patrizia; Stoppacciaro, Antonella - 01a Articolo in rivista
rivista: CLINICAL EPIGENETICS (Berlin : Springer) pp. 1-16 - issn: 1868-7083 - wos: WOS:000429840100001 (10) - scopus: 2-s2.0-85045003305 (12)

11573/1147231 - 2018 - Lysine acetyltransferase inhibitors: structure-activity relationships and potential therapeutic implications
Fiorentino, Francesco; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
rivista: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 1067-1091 - issn: 1756-8919 - wos: WOS:000431874300008 (24) - scopus: 2-s2.0-85046873546 (24)

11573/1174039 - 2018 - Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells
Iachettini, Sara; Trisciuoglio, Daniela; Rotili, Dante; Lucidi, Alessia; Salvati, Erica; Zizza, Pasquale; Di Leo, Luca; Del Bufalo, Donatella; Rosa Ciriolo, Maria; Leonetti, Carlo; Steegborn, Clemens; Mai, Antonello; Rizzo, Angela; Annamaria Biroccio, And - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. 996- - issn: 2041-4889 - wos: WOS:000446267200026 (67) - scopus: 2-s2.0-85053859793 (75)

11573/1118719 - 2018 - Mass spectrometry characterization of DOTA-Nimotuzumab conjugate as precursor of an innovative β − tracer suitable in radio-guided surgery
Martelli, C.; Marzano, V.; Marini, F.; Scotognella, T.; Fratoddi, I.; Venditti, I; Rotili, D.; Solfaroli C., E.; Collamati, F.; Mancini T., C.; Morganti, S.; Maccora, D.; Faccini, R.; Cartoni, A; Giordano, A.; Castagnola, M. - 01a Articolo in rivista
rivista: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (Oxford ; New York : Pergamon Press Amsterdam : Elsevier Science) pp. 8-15 - issn: 0731-7085 - wos: WOS:000435228400002 (5) - scopus: 2-s2.0-85046479862 (6)

11573/1065694 - 2018 - Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches
Sabatino, Manuela; Rotili, Dante; Patsilinakos, Alexandros; Forgione, Mariantonietta; Tomaselli, Daniela; Alby, Fréderic; Arimondo, Paola B.; Mai, Antonello; Ragno, Rino - 01a Articolo in rivista
rivista: JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (-SPRINGER, VAN GODEWIJCKSTRAAT 30, DORDRECHT, NETHERLANDS, 3311 GZ -Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: frontoffice@wkap.nl, kluweronline@wkap.nl, INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254) pp. 435-458 - issn: 0920-654X - wos: WOS:000425293300003 (16) - scopus: 2-s2.0-85041359880 (15)

11573/1602341 - 2017 - Corrigendum: Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma
Coni, S.; Mancuso, A. B.; Di Magno, L.; Sdruscia, G.; Manni, S.; Serrao, S. M.; Rotili, D.; Spiombi, E.; Bufalieri, F.; Petroni, M.; Kusio-Kobialka, M.; De Smaele, E.; Ferretti, E.; Capalbo, C.; Mai, A.; Niewiadomski, P.; Screpanti, I.; Di Marcotullio, L.; Canettieri, G. - 01b Commento, Erratum, Replica e simili
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000399974300001 (5) - scopus: 2-s2.0-85068766477 (4)

11573/946157 - 2017 - Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.
Coni, Sonia; Mancuso, Anna Barbara; Di Magno, L; Sdruscia, Giulia; Manni, Simona; Serrao, Silvia Maria; Rotili, Dante; Spiombi, Eleonora; Bufalieri, Francesca; Petroni, Marialaura; Kusio Kobialka, M; De Smaele, Enrico; Ferretti, Elisabetta; Capalbo, Carlo; Mai, Antonello; Niewiadomski, P; Screpanti, Isabella; Di Marcotullio, Lucia; Canettieri, Gianluca - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 44079- - issn: 2045-2322 - wos: WOS:000396136700001 (54) - scopus: 2-s2.0-85014895304 (54)

11573/944093 - 2017 - The nitrobenzoxadiazole derivative MC3181 blocks melanoma invasion and metastasis.
De Luca, A; Carpanese, D; Rapanotti, Mc; Viguria, Tm; Forgione, Ma; Rotili, Dante; Fulci, C; Iorio, E; Quintieri, L; Chimenti, S; Bianchi, L; Rosato, A; Caccuri, A. M. 1. - 01a Articolo in rivista
rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 15520-15538 - issn: 1949-2553 - wos: WOS:000396013700106 (17) - scopus: 2-s2.0-85014078650 (18)

11573/944092 - 2017 - A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability.
Fulci, C; Rotili, Dante; De Luca, A; Stella, L; Morozzo Della Rocca, B; Forgione, M; Di Paolo, V; Mai, Antonello; Falconi, M; Quintieri, L; Caccuri, Am; 7, . - 01a Articolo in rivista
rivista: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 240-247 - issn: 1475-6366 - wos: WOS:000392591100017 (18) - scopus: 2-s2.0-85015590345 (18)

11573/1027812 - 2017 - Lysine deacetylase inhibitors in parasites: past, present, and future perspectives.
Hailu, Gs; Robaa, D; Forgione, M; Sippl, W; Rotili, D; Mai, A. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4780-4804 - issn: 0022-2623 - wos: WOS:000404202200002 (69) - scopus: 2-s2.0-85021131721 (76)

11573/1027154 - 2017 - Feasibility of beta-particle radioguided surgery for a variety of “nuclear medicine” radionuclides
Mancini Terracciano, C; Donnarumma, R; Bencivenga, G.; Bocci, V.; Cartoni, A.; Collamati, F.; Fratoddi, I.; Giordano, A.; Indovina, L.; Maccora, D.; Marafini, M.; Mirabelli, R.; Morganti, S.; Rotili, D.; Russomando, A.; Scotognella, T.; Solfaroli C, E.; Toppi, M; Traini, G.; Venditti, I.; Faccini, R. - 01a Articolo in rivista
rivista: PHYSICA MEDICA (UK: Elsevier Pisa: Istituti Editoriali e Poligrafici Internazionali. Pisa Italy: Giardini Editori Stampatori) pp. 127-133 - issn: 1120-1797 - wos: WOS:000417655800016 (22) - scopus: 2-s2.0-85036555361 (25)

11573/947675 - 2017 - Development of 1,2,4-oxadiazoles as potent and selective inhibitors of the human deacetylase sirtuin 2: structure-activity relationship, X-ray crystal structure, and anticancer activity
Moniot, S; Forgione, M; Lucidi, Alessia; Hailu, Gebremedhin Solomon; Nebbioso, A; Carafa, V; Baratta, F; Altucci, L; Giacché, N; Passeri, D; Pellicciari, R; Mai, Antonello; Steegborn, C; Rotili, Dante - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2344-2360 - issn: 0022-2623 - wos: WOS:000397546000013 (79) - scopus: 2-s2.0-85016147565 (81)

11573/944090 - 2017 - Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity.
Ourailidou, Me; Lenoci, A; Zwergel, Clemens; Rotili, Dante; Mai, Antonello; Dekker, F. J. 4. - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 847-856 - issn: 0968-0896 - wos: WOS:000394201900004 (9) - scopus: 2-s2.0-85008433321 (10)

11573/1027813 - 2017 - Crystal structures of the mitochondrial deacylase Sirtuin 4 reveal isoform-specific acyl recognition and regulation features.
Pannek, M; Simic, Z; Fuszard, M; Meleshin, M; Rotili, D; Mai, A; Schutkowski, M; Steegborn, C. - 01a Articolo in rivista
rivista: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. - - issn: 2041-1723 - wos: WOS:000415262500001 (72) - scopus: 2-s2.0-85034035870 (74)

11573/1017768 - 2017 - Y3+ embedded in polymeric nanoparticles: Morphology, dimension and stability of composite colloidal system
Venditti, I; Cartoni, A.; Fontana, L.; Testa, G.; Scaramuzzo, F. A.; Faccini, R.; Mancini Terracciano, C.; Solfaroli Camillocci, E.; Morganti, S.; Giordano, A.; Scotognella, T.; Rotili, D.; Dini, V.; Marini, F.; Fratoddi, I - 01a Articolo in rivista
rivista: COLLOIDS AND SURFACES. A, PHYSICOCHEMICAL AND ENGINEERING ASPECTS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 125-131 - issn: 0927-7757 - wos: WOS:000412065600018 (20) - scopus: 2-s2.0-85020137711 (20)

11573/1027810 - 2017 - The relevance of Ki calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor.
Wapenaar, H; Van Den Bosch, T; Leus, Ngj; Van Der Wouden, Pe; Eleftheriadis, N; Hermans, J; Hailu, Gs; Rotili, D; Mai, A; Dömling, A; Bischoff, R; Haisma, Hj; Dekker, F. J. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 480-486 - issn: 0223-5234 - wos: WOS:000403993500041 (6) - scopus: 2-s2.0-85019413230 (6)

11573/944091 - 2017 - Structural basis of sirtuin 6 activation by synthetic small molecules.
You, W; Rotili, Dante; Li, Tm; Kambach, C; Meleshin, M; Schutkowski, M; Chua, Kf; Mai, Antonello; Steegborn, C. 1. - 01a Articolo in rivista
rivista: ANGEWANDTE CHEMIE. INTERNATIONAL EDITION (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 1007-1011 - issn: 1433-7851 - wos: WOS:000394997200011 (116) - scopus: 2-s2.0-85006998900 (127)

11573/884147 - 2016 - Sirtuin functions and modulation: from chemistry to the clinic
Carafa, Vincenzo; Rotili, Dante; Forgione, Mariantonietta; Cuomo, Francesca; Serretiello, Enrica; Hailu, Gebremedhin Solomon; Jarho, Elina; Lahtela Kakkonen, Maija; Mai, Antonello; Altucci, Lucia - 01a Articolo in rivista
rivista: CLINICAL EPIGENETICS (Berlin : Springer) pp. 1-21 - issn: 1868-7083 - wos: WOS:000376856700001 (269) - scopus: 2-s2.0-84973864104 (288)

11573/884154 - 2016 - Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells
Chano, Tokuhiro; Avnet, Sofia; Kusuzaki, Katsuyuki; Bonuccelli, Gloria; Sonveaux, Pierre; Rotili, Dante; Mai, Antonello; Baldini, Nicola - 01a Articolo in rivista
rivista: AMERICAN JOURNAL OF CANCER RESEARCH (Madison, WI: Published by e-Century Publishing Corporation, Madison) pp. 859-875 - issn: 2156-6976 - wos: WOS:000384444300002 (29) - scopus: 2-s2.0-84991518619 (32)

11573/884170 - 2016 - Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells
Di Martile, Marta; Desideri, Marianna; De Luca, Teresa; Gabellini, Chiara; Buglioni, Simonetta; Eramo, Adriana; Sette, Giovanni; Milella, Michele Stanislaw; Rotili, Dante; Mai, Antonello; Carradori, Simone; Secci, Daniela; De Maria, Ruggero; Del Bufalo, Donatella; Trisciuoglio, Daniela - 01a Articolo in rivista
rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 11332-11348 - issn: 1949-2553 - wos: WOS:000375678300047 (37) - scopus: 2-s2.0-84962019515 (38)

11573/871180 - 2016 - c-Jun N-terminal kinase activation by nitrobenzoxadiazoles leads to late-stage autophagy inhibition
Palumbo, Camilla; De Luca, Anastasia; Rosato, Nicola; Forgione, Mariantonietta; Rotili, Dante; Caccuri, Anna Maria - 01a Articolo in rivista
rivista: JOURNAL OF TRANSLATIONAL MEDICINE (London: BioMed Central, London) pp. - - issn: 1479-5876 - wos: WOS:000369219900001 (23) - scopus: 2-s2.0-84958170303 (23)

11573/894532 - 2016 - At long last potent and selective KDM5 inhibitors
Rotili, Dante; Mattevi, Andrea - 01a Articolo in rivista
rivista: CELL CHEMICAL BIOLOGY (Amsterdam : Elsevier Cambridge, MA : Cell Press) pp. 749-751 - issn: 2451-9456 - wos: WOS:000381509200001 (4) - scopus: 2-s2.0-84984910817 (4)

11573/894534 - 2016 - Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features
Speranzini, Valentina; Rotili, Dante; Ciossani, Giuseppe; Pilotto, Simona; Marrocco, Biagina; Forgione, Mariantonietta; Lucidi, Alessia; Forneris, Federico; Mehdipour, Parinaz; Velankar, Sameer; Mai, Antonello; Mattevi, Andrea - 01a Articolo in rivista
rivista: SCIENCE ADVANCES (Washington, DC : American Association for the Advancement of Science, 2015-) pp. - - issn: 2375-2548 - wos: WOS:000383734400025 (59) - scopus: 2-s2.0-85020596495 (60)

11573/884171 - 2016 - The histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases
Van Den Bosch, Thea; Boichenko, Alexander; Leus, Niek G. J.; Ourailidou, Maria E.; Wapenaar, Hannah; Rotili, Dante; Mai, Antonello; Imhof, Axel; Bischoff, Rainer; Haisma, Hidde J.; Dekker, Frank J. - 01a Articolo in rivista
rivista: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited -London ; New York : Pergamon Press, 1958-) pp. 130-140 - issn: 0006-2952 - wos: WOS:000371446300011 (39) - scopus: 2-s2.0-84958753301 (50)

11573/884205 - 2015 - A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts
De Luca, Anastasia; Rotili, Dante; Carpanese, Debora; Lenoci, Alessia; Calderan, Laura; Scimeca, Manuel; Mai, Antonello; Bonanno, Elena; Rosato, Antonio; Geroni, Cristina; Quintieri, Luigi; Caccuri, Anna Maria - 01a Articolo in rivista
rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 4126-4143 - issn: 1949-2553 - wos: WOS:000352696200052 (23) - scopus: 2-s2.0-84924251939 (26)

11573/784167 - 2015 - Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells
G., Di Pompo; M., Salerno; Rotili, Dante; Valente, Sergio; Zwergel, Clemens; S., Avnet; G., Lattanzi; N., Baldini; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4073-4079 - issn: 0022-2623 - wos: WOS:000354911200031 (55) - scopus: 2-s2.0-84929378676 (54)

11573/884194 - 2015 - A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib
Graziani, Grazia; Artuso, Simona; De Luca, Anastasia; Muzi, Alessia; Rotili, Dante; Scimeca, Manuel; Atzori, Maria Grazia; Ceci, Claudia; Mai, Antonello; Leonetti, Carlo; Levati, Lauretta; Bonanno, Elena; Tentori, Lucio; Caccuri, Anna Maria - 01a Articolo in rivista
rivista: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited -London ; New York : Pergamon Press, 1958-) pp. 16-27 - issn: 0006-2952 - wos: WOS:000353858800002 (29) - scopus: 2-s2.0-84930886228 (29)

11573/789900 - 2015 - SIRT5 regulation of ammonia-induced autophagy and mitophagy
Polletta, Lucia; Vernucci, Enza; Carnevale, Ilaria; Arcangeli, Tania; Rotili, Dante; Palmerio, Silvia; Steegborn, Clemens; Nowak, Theresa; Schutkowski, Mike; Pellegrini, Laura; Sansone, Luigi; Villanova, Lidia; Runci, Alessandra; Pucci, Bruna; Morgante, Emanuela; Fini, Massimo; Mai, Antonello; Russo, Matteo A; Tafani, Marco - 01a Articolo in rivista
rivista: AUTOPHAGY (Landes Bioscience Georgetown TX 78628) pp. 253-270 - issn: 1554-8627 - wos: WOS:000352778700007 (218) - scopus: 2-s2.0-84943265499 (223)

11573/680651 - 2015 - Synthesis and structure-activity relationship of new cytotoxic agents targeting human glutathione-S-transferases.
Rotili, Dante; De Luca, A; Tarantino, D; Pezzola, S; Forgione, Mariantonietta; Morozzo Della Rocca, B; Falconi, M; Mai, Antonello; Caccuri, A. M. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 156-171 - issn: 0223-5234 - wos: WOS:000348003500017 (31) - scopus: 2-s2.0-84908450815 (33)

11573/779609 - 2015 - Pyrrole- and indole-containing tranylcypromine derivatives as novel lysine-specific demethylase 1 inhibitors active on cancer cells.
Veronica, Rodriguez; Valente, Sergio; Stefano, Rovida; Rotili, Dante; Stazi, Giulia; Lucidi, Alessia; Giuseppe, Ciossani; Andrea, Mattevi; Oronza A., Botrugno; Paola, Dessanti; Ciro, Mercurio; Paola, Vianello; Saverio, Minucci; Mario, Varasi; Mai, Antonello - 01a Articolo in rivista
rivista: MEDCHEMCOMM (Cambridge : Royal Society of Chemistry, 2010-) pp. 665-670 - issn: 2040-2503 - wos: WOS:000352903400023 (22) - scopus: 2-s2.0-84928004801 (23)

11573/884188 - 2015 - Targeting lysine deacetylases (KDACs) in parasites
Wang, Qi; Rosa, Bruce A.; Nare, Bakela; Powell, Kerrie; Valente, Sergio; Rotili, Dante; Mai, Antonello; Marshall, Garland R.; Mitreva, Makedonka - 01a Articolo in rivista
rivista: PLOS NEGLECTED TROPICAL DISEASES (San Francisco, CA : Public Library of Science) pp. e000426- - issn: 1935-2727 - wos: WOS:000363031200020 (38) - scopus: 2-s2.0-84943193825 (42)

11573/884182 - 2015 - Enzyme kinetics and inhibition of histone acetyltransferase KAT8
Wapenaar, Hannah; Van Der Wouden, Petra E; Groves, Matthew R; Rotili, Dante; Mai, Antonello; Dekker, Frank J. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ([Paris] : Elsevier, [198?]-) pp. 289-296 - issn: 1768-3254 - wos: WOS:000364891400020 (26) - scopus: 2-s2.0-84945264596 (28)

11573/1155213 - 2014 - Sirtuins blunt reactive gliosis in an in vitro model of Alzheimer’s disease.
Bronzuoli, Maria Rosanna; Scuderi, Caterina; Stecca, Claudia; Rotili, Dante; Valente, Sergio; Cugno, Michele; Mai, Antonello; Steardo, Luca. - 04d Abstract in atti di convegno
congresso: 17° Simposio SIF Dottorandi, Assegnisti di Ricerca Postdottorandi e Specializzandi in Farmacologia e Scienze Affini (Rimini)
libro: 17° Simposio SIF Dottorandi, Assegnisti di Ricerca Postdottorandi e Specializzandi in Farmacologia e Scienze Affini. - ()

11573/685071 - 2014 - Evaluation of a large library of (thiazol-2-yl)hydrazones and analogues as histone acetyltransferase inhibitors: Enzyme and cellular studies.
Carradori, S; Rotili, Dante; De Monte, Celeste; Lenoci, A; D'ascenzio, M; Rodriguez, V; Filetici, Patrizia; Miceli, M; Nebbioso, A; Altucci, L; Secci, Daniela; Mai, Antonello - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 569-578 - issn: 0223-5234 - wos: WOS:000337985400049 (47) - scopus: 2-s2.0-84900559630 (53)

11573/556419 - 2014 - Context-Selective Death of Acute Myeloid Leukemia Cells Triggered by the Novel Hybrid Retinoid-HDAC Inhibitor MC2392.
De Bellis, F; Carafa, V; Conte, M; Rotili, Dante; Petraglia, F; Matarese, F; Françoijs, Kj; Ablain, J; Valente, Sergio; Castellano, R; Goubard, A; Collette, Y; Mandoli, A; Martens, Jh; De Thé, H; Nebbioso, A; Mai, Antonello; Stunnenberg, Hg; Altucci, L. - 01a Articolo in rivista
rivista: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 2328-2339 - issn: 0008-5472 - wos: WOS:000334584200020 (28) - scopus: 2-s2.0-84899541163 (33)

11573/556417 - 2014 - Quinoline-based p300 histone acetyltransferase inhibitors with pro-apoptotic activity in human leukemia U937 cells.
Lenoci, Alessia; Tomassi, S; Conte, M; Benedetti, R; Rodriguez, V; Carradori, Simone; Secci, Daniela; Castellano, S; Sbardella, G; Filetici, P; Novellino, E; Altucci, L; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 542-548 - issn: 1860-7187 - wos: WOS:000331795500010 (26) - scopus: 2-s2.0-84896698147 (27)

11573/542432 - 2014 - Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities
Rotili, Dante; Stefano, Tomassi; Mariarosaria, Conte; Rosaria, Benedetti; Marcello, Tortorici; Giuseppe, Ciossani; Valente, Sergio; Marrocco, Biagina; Labella, Donatella; Ettore, Novellino; Andrea, Mattevi; Lucia, Altucci; Tumber, Anthony; Yapp, Clarence; N. F., King Oliver; Richard J., Hopkinson; Akane, Kawamura; J., Schofield Christopher; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 42-55 - issn: 0022-2623 - wos: WOS:000329677800004 (94) - scopus: 2-s2.0-84892565144 (103)

11573/681257 - 2014 - Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity.
Rotili, Dante; Tarantino, D; Marrocco, Biagina; Gros, C; Masson, V; Poughon, V; Ausseil, F; Chang, Y; Labella, D; Cosconati, S; Di Maro, S; Novellino, E; Schnekenburger, M; Grandjenette, C; Bouvy, C; Diederich, M; Cheng, X; Arimondo, Pb; Mai, Antonello - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. - - issn: 1932-6203 - wos: WOS:000338213300096 (31) - scopus: 2-s2.0-84901487126 (35)

11573/681252 - 2014 - Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes
Rotili, Dante; Tarantino, D; Nawrozkij, Mb; Babushkin, As; Botta, G; Marrocco, Biagina; Cirilli, R; Menta, Sergio; Badia, R; Crespan, E; Ballante, Flavio; Ragno, Rino; Esté, Ja; Maga, G; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5212-5225 - issn: 0022-2623 - wos: WOS:000338184100018 (18) - scopus: 2-s2.0-84903515653 (18)

11573/643824 - 2014 - Sirtuin modulators control reactive gliosis in an in vitro model of alzheimer's disease
Scuderi, Caterina; Stecca, Claudia; Bronzuoli, Maria Rosanna; Rotili, Dante; Valente, Sergio; Mai, Antonello; Steardo, Luca - 01a Articolo in rivista
rivista: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000347086800001 (52) - scopus: 2-s2.0-84904631078 (56)

11573/553541 - 2014 - I kappa B kinase (IKK)-epsilon targets interferon regulatory factor 1 in activated T lymphocytes.
Sgarbanti, M; Marsili, G; Remoli, Al; Stellacci, E; Mai, Antonello; Rotili, Dante; Perrotti, E; Acchioni, C; Orsatti, R; Iraci, N; Ferrari, M; Borsetti, A; Hiscott, J; Battistini, A. - 01a Articolo in rivista
rivista: MOLECULAR AND CELLULAR BIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 1054-1065 - issn: 0270-7306 - wos: WOS:000331995800012 (28) - scopus: 2-s2.0-84894284462 (30)

11573/513467 - 2013 - Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue.
Galmozzi, A.; Mitro, N.; Ferrari, A.; Gers, E.; Gilardi, F.; Godio, C.; Cermenati, G.; Gualerzi, A.; Donetti, E.; Rotili, Dante; Valente, Sergio; Guerrini, U.; Caruso, D.; Mai, Antonello; Saez, E.; De Fabiani, E.; Crestani, M. - 01a Articolo in rivista
rivista: DIABETES (American Diabetes Association:National Service Center, 1701 North Beaureguard Street:Alexandria, VA 22311:(800)232-3472, (703)549-1500, INTERNET: http://www.diabetes.org/diabetscare, Fax: (703)549-6995) pp. 732-742 - issn: 0012-1797 - wos: WOS:000315556400017 (183) - scopus: 2-s2.0-84869106554 (198)

11573/525206 - 2013 - PARP-1 Modulates Amyloid Beta Peptide-Induced Neuronal Damage
Martire, Sara; Fuso, Andrea; Rotili, Dante; Tempera, Italo; Giordano, Cesare Giovanni; Ivana De, Zottis; Alessia, Muzi; Patrizia, Vernole; Grazia, Graziani; Emanuela, Lococo; Faraldi, Martina; Maras, Bruno; Scarpa, Sigfrido; Mosca, Luciana; D'erme, Maria - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e72169- - issn: 1932-6203 - wos: WOS:000325025200005 (55) - scopus: 2-s2.0-84884573236 (65)

11573/525223 - 2013 - ROLE OF POLY(ADP-RIBOSE)POLYMERASE IN AMYLOID BETA TOXICITY AND ALZHEIMER DISEASE
Mosca, Luciana; Fuso, Andrea; Martire, Sara; Rotili, Dante; Giordano, Cesare Giovanni; Emanuela, Lococo; Faraldi, Martina; P., Vernole; G., Graziani; Francioso, Antonio; Maras, Bruno; M., D'erme - 04a Atto di comunicazione a congresso
congresso: AD/PD 2013 (Firenze)
libro: Abstract book - ()

11573/442878 - 2012 - An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases
Anup K., Upadhyay; Rotili, Dante; Ji Woong, Han; Ruogu, Hu; Yanqi, Chang; Donatella, Labella; Xing, Zhang; Young Sup, Yoon; Mai, Antonello; Xiaodong, Cheng - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, -London; New York: Academic Press.) pp. 319-327 - issn: 0022-2836 - wos: WOS:000301313600001 (44) - scopus: 2-s2.0-84862777760 (47)

11573/511464 - 2012 - PARP-1 inhibition decreases Beta-Amyloid-induced neurodegeneration: a cellular and animal model study
Martire, Sara; Fuso, Andrea; Rotili, Dante; A., Muzi; Giordano, Cesare Giovanni; P., Vernole; E., Lococo; Faraldi, Martina; Masci, Alessandra; Miele, Adriana Erica; G., Graziani; Scarpa, Sigfrido; Mosca, Luciana; D'erme, Maria - 04c Atto di convegno in rivista
rivista: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. S182- - issn: 0891-5849 - wos: WOS:000209480800378 (0) - scopus: (0)
congresso: 16th SFRRI Biennial Meeting (London)

11573/895421 - 2012 - 6-(Arylmethyl)pyrimidin-4(3H)-ones: Anthology and prospects of highly efficient anti-HIV agents
Novakov, I. A.; Artico, M.; Mai, Antonello; Rotili, Dante; Orlinson, B. S.; Brunilina, L. L.; Nawrozkij, M. B. - 01a Articolo in rivista
rivista: RUSSIAN CHEMICAL BULLETIN (- New York : SPRINGER -New York : Consultants Bureau, c1993-) pp. 1399-1418 - issn: 1066-5285 - wos: WOS:000321771700009 (11) - scopus: 2-s2.0-84887395127 (11)

11573/495328 - 2012 - Carprofen Analogues as Sirtuin Inhibitors: Enzyme and Cellular Studies
Paolo, Mellini; Vincenzo, Carafa; Barbara Di, Rienzo; Rotili, Dante; De Vita, Daniela; Roberto, Cirilli; Bruno, Gallinella; Donatella Paola, Provvisiero; Salvatore Di, Maro; Ettore, Novellino; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1905-1908 - issn: 1860-7187 - wos: WOS:000310485200005 (14) - scopus: 2-s2.0-84868149996 (15)

11573/455654 - 2012 - 2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies.
Rotili, Dante; A., Samuele; Domenico, Tarantino; Ragno, Rino; Musmuca, Ira; Ballante, Flavio; G., Botta; Morera, Ludovica; Pierini, Marco; R., Cirilli; M. B., Nawrozkij; E., Gonzalez; B., Clotet; Marino, Artico; J. A., Este; G., Maga; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 3558-3562 - issn: 1520-4804 - wos: WOS:000302591100058 (29) - scopus: 2-s2.0-84859804994 (31)

11573/485200 - 2012 - Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells.
Rotili, Dante; Tarantino, D; Carafa, V; Paolini, C; Schemies, J; Jung, M; Botta, G; Di Maro, S; Novellino, E; Steinkühler, C; De Maria, R; Gallinari, P; Altucci, L; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8193-8197 - issn: 0022-2623 - wos: WOS:000309153500023 (28) - scopus: 2-s2.0-84866849116 (35)

11573/759461 - 2012 - Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells.
Rotili, Dante; Tarantino, D; Nebbioso, A; Paolini, C; Huidobro, C; Lara, E; Mellini, P; Lenoci, Alessia; Pezzi, R; Botta, G; Lahtela Kakkonen, M; Poso, A; Steinkühler, C; Gallinari, P; De Maria, R; Fraga, M; Esteller, M; Altucci, L; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 10937-10947 - issn: 0022-2623 - wos: WOS:000312681100009 (76) - scopus: 2-s2.0-84871662210 (82)

11573/485203 - 2012 - p300/CBP-associated factor selectively regulates the extinction of conditioned fear.
W., Wei; C. M., Coelho; X., Li; R., Marek; S., Yan; S., Anderson; D., Meyers; C., Mukherjee; G., Sbardella; S., Castellano; C., Milite; Rotili, Dante; Mai, Antonello; P. A., Cole; P., Sah; M. S., Kobor; T. W., Bredy - 01a Articolo in rivista
rivista: THE JOURNAL OF NEUROSCIENCE (Baltimore MD: Society of Neuroscience) pp. 11930-11941 - issn: 0270-6474 - wos: WOS:000308213900003 (71) - scopus: 2-s2.0-84865472870 (76)

11573/442881 - 2011 - Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors
Gianluca, Sbardella; Mai, Antonello; Sara, Bartolini; Sabrina, Castellano; Roberto, Cirilli; Rotili, Dante; Ciro, Milite; Marisabella, Santoriello; Serena, Orlando; Ilaria, Sciamanna; Annalucia, Serafino; Patrizia, Lavia; Corrado, Spadafora - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5927-5936 - issn: 0022-2623 - wos: WOS:000294077300023 (12) - scopus: 2-s2.0-80051873043 (14)

11573/442885 - 2011 - Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3'-C-methyladenosine in leukaemia cells.
Meli, M; Tolomeo, M; Grifantini, M; Mai, Antonello; Cappellacci, L; Petrelli, R; Rotili, Dante; Ferro, A; Saiko, P; Szekeres, T; Dusonchet, L. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF ONCOLOGY (National Hellenic Research Foundation:48 Vas Constatinou Avenue, Athens 11635 Greece:011 30 1 7241505, Fax: 011 30 1 7241505Editore attuale:PROFESSOR D A SPANDIDOS, 1, S MERKOURI ST, EDITORIAL OFFICE,, ATHENS, GREECE, 116 35. Editore precedente:Editorial Academy of the International Journal of Oncology.) pp. - - issn: 1019-6439 - wos: WOS:000289815800026 (9) - scopus: 2-s2.0-79954993415 (9)

11573/511590 - 2011 - Apoptotic events are modulated by poly(ADP-ribose)polymerase in cellular and animal models of Alzheimer disease
Mosca, Luciana; Fuso, Andrea; Aureli, Cristina; Martire, Sara; Masci, Alessandra; Rotili, Dante; De Leo, Alessandra; Giordano, Cesare Giovanni; Scarpa, Sigfrido; D'erme, Maria - 04a Atto di comunicazione a congresso
libro: Abstract book - ()

11573/511592 - 2011 - PARP activation modulates apoptosis events in cellular and animal models of Alzheimer disease
Mosca, Luciana; Martire, Sara; Fuso, Andrea; D., Beyaie; Masci, Alessandra; Rotili, Dante; De Leo, Alessandra; Consalvi, Valerio; Giordano, Cesare Giovanni; Scarpa, Sigfrido; D'erme, Maria - 04a Atto di comunicazione a congresso
congresso: Molecular Mechanisms of Neurodegeneration (Milan, Italy,)
libro: Abstract book - ()

11573/379664 - 2011 - Biological Effects of MC2050, a Quinazoline-Based PARP-1 Inhibitor, in Human Neuroblastoma and EBV-Positive Burkitt's Lymphoma Cells
Mosca, Luciana; Rotili, Dante; Tempera, Italo; Masci, Alessandra; Fontana, Mario; Chiaraluce, Roberta; Mastromarino, Paola; D'erme, Maria; Mai, Antonello - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 606-611 - issn: 1860-7179 - wos: WOS:000288814900006 (12) - scopus: 2-s2.0-79953056639 (11)

11573/442676 - 2011 - Photoactivable peptides for identifying enzyme-substrate and protein-protein interactions.
Rotili, Dante; Altun, M; Hamed, Rb; Loenarz, C; Thalhammer, A; Hopkinson, Rj; Tian, Ym; Ratcliffe, Pj; Mai, Antonello; Kessler, Bm; Schofield, C. J. - 01a Articolo in rivista
rivista: CHEMICAL COMMUNICATIONS (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 1488-1490 - issn: 1359-7345 - wos: WOS:000286389500026 (5) - scopus: 2-s2.0-78751521073 (5)

11573/442886 - 2011 - Targeting histone demethylases: A new avenue for the fight against cancer
Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
rivista: GENES & CANCER (Thousand Oaks, CA: SAGE Publications) pp. 663-679 - issn: 1947-6019 - wos: (0) - scopus: 2-s2.0-80054787805 (173)

11573/442882 - 2011 - A Photoreactive Small-Molecule Probe for 2-Oxoglutarate Oxygenases
Rotili, Dante; Mikael, Altun; Akane, Kawamura; Alexander, Wolf; Roman, Fischer; I. K., Leung; Mukram M, Mackeen; Ya Min, Tian; Peter J, Ratcliffe; Mai, Antonello; Benedikt M, Kessler; Christopher J, Schofield - 01a Articolo in rivista
rivista: CHEMISTRY & BIOLOGY (Current Science:400 Market Street, Suite 700:Philadelphia, PA 19106:(800)427-1796, (215)574-2266, EMAIL: info@phl.cursci.com, INTERNET: http://www-current-science-group.com, Fax: (215)574-2225) pp. 642-654 - issn: 1074-5521 - wos: WOS:000291499600013 (43) - scopus: 2-s2.0-79957487715 (45)

11573/379781 - 2011 - Diarylpyrimidine-Dihydrobenzyloxopyrimidine Hybrids: New, Wide-Spectrum Anti-HIV-1 Agents Active at (Sub)-Nanomolar Level.
Rotili, Dante; Tarantino, D; Artico, M; Nawrozkij, Mb; Gonzalez Ortega, E; Clotet, B; Samuele, A; Este, Ja; Maga, G; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3091-3096 - issn: 0022-2623 - wos: WOS:000289697800043 (47) - scopus: 2-s2.0-79955455754 (52)

11573/442679 - 2011 - Simplification of the tetracyclic SIRT1-selective inhibitor MC2141: Coumarin- and pyrimidine-based SIRT1/2 inhibitors with different selectivity profile
Rotili, Dante; Vincenzo, Carafa; Domenico, Tarantino; Giorgia, Botta; Angela, Nebbioso; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 3659-3668 - issn: 0968-0896 - wos: WOS:000291477600007 (28) - scopus: 2-s2.0-79958261783 (30)

11573/434969 - 2010 - HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation
A., Nebbioso; C., Dell'aversana; A., Bugge; R., Sarno; Valente, Sergio; Rotili, Dante; F., Manzo; D., Teti; S., Mandrup; P., Ciana; A., Maggi; Mai, Antonello; H., Gronemeyer; L., Altucci - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR ENDOCRINOLOGY (Pubblicata da: SOC ENDOCRINOLOGY, 22 APEX COURT, WOODLANDS, BRADLEY STOKE, BRISTOL, ENGLAND, BS32 4JT primo editore: Journal of Endocrinology Limited:17 18 Courtyard Woodlands, Bristol BS12 4NQ United Kingdom:011 44 117 9616046, EMAIL: sxa15@psu.edu, INTERNET: http://www.psu.edu, Fax: 011 44 117 9616071) pp. 219-228 - issn: 0952-5041 - wos: WOS:000282528800005 (51) - scopus: 2-s2.0-77957824326 (55)

11573/13728 - 2010 - Proteomic profile of differentially expressed plasma proteins from dystrophic mice and following suberoylanilide hydroxamic acid treatment
Colussi, C.; Banfi, C.; Brioschi, M.; Tremoli, E.; Straino, S.; Spallotta, F.; Mai, Antonello; Rotili, Dante; Capogrossi Mc, Gaetano C. - 01a Articolo in rivista
rivista: PROTEOMICS. CLINICAL APPLICATIONS (Weinheim : Wiley-VCH-Verl.) pp. 71-83 - issn: 1862-8346 - wos: WOS:000274264900007 (29) - scopus: 2-s2.0-77951727320 (31)

11573/13666 - 2010 - The histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces cardiac arrhythmias in dystrophic mice
Colussi, C.; Berni, R.; Rosati, J.; Straino, S.; Vitale, S.; Spallotta, F.; Baruffi, S.; Bocchi, L.; Delucchi, F.; Rossi, S.; Savi, M.; Rotili, Dante; Quaini, F.; Macchi, E.; Stilli, D.; Musso, E.; Mai, Antonello; Capogrossi Mc, Gaetano C. - 01a Articolo in rivista
rivista: CARDIOVASCULAR RESEARCH (editore attuale: ELSEVIER SCIENCE BV, PO BOX 211, AMSTERDAM, NETHERLANDS, 1000 AE primo editore: BMJ / British Medical Journal Publishing Group:PO Box 299, London WC1H 9TD United Kingdom:011 44 20 73836270, EMAIL: subscriptions@bmjgroup.com, INTERNET: http://www.bmjpg.com/bmj, Fax: 011 44 20 73836402) pp. 73-82 - issn: 0008-6363 - wos: WOS:000278690000012 (40) - scopus: 2-s2.0-77955165005 (42)

11573/442677 - 2010 - Characterization of Sirtuin Inhibitors in Nematodes Expressing a Muscular Dystrophy Protein Reveals Muscle Cell and Behavioral Protection by Specific Sirtinol Analogues
Matthieu Y., Pasco; Rotili, Dante; Lucia, Altucci; Francesca, Farina; Guy A., Rouleau; Mai, Antonello; Christian, Neri - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1407-1411 - issn: 0022-2623 - wos: WOS:000274270900047 (35) - scopus: 2-s2.0-77249153712 (38)

11573/456124 - 2010 - The specific character of the reaction of derivatives of 2-thioxo-2,3-dihydropyrimidin-4(1H)-one with iodomethane and alkyl chloromethyl sulfides.
Novakov, Ia; Orlinson, B; Nawrozkij, Mb; Mai, Antonello; Artico, Marino; Rotili, Dante; Eremiychuk, As; Gordeeva, Ea; Brunilina, Ll; Este, J. A. - 01a Articolo in rivista
rivista: CHEMISTRY OF HETEROCYCLIC COMPOUNDS (Consultants Bureau:A Division of Plenum Publishing Corporation, 233 Spring Street, Sixth Floor:New York, NY 10013:(800)221-9369, (212)620-8082, Fax: (212)463-0742) pp. - - issn: 0009-3122 - wos: WOS:000279454900010 (1) - scopus: 2-s2.0-77954638922 (0)

11573/895420 - 2010 - Evaluation of histone deacetylases as drug targets in Huntington's disease models
Quinti, Luisa; Chopra, Vanita; Rotili, Dante; Valente, Sergio; Amore, Allison; Franci, Gianluigi; Meade, Sarah; Valenza, Marta; Altucci, Lucia; Maxwell, Michele M.; Cattaneo, Elena; Hersch, Steven; Mai, Antonello; Kazantsev, Aleksey - 02a Capitolo o Articolo
libro: PLOS CURRENTS - ()

11573/456116 - 2010 - Identification of Tri- and Tetracyclic Pyrimidinediones as Sirtuin Inhibitors
Rotili, Dante; Tarantino, Domenico; Vincenzo, Carafa; Ester, Lara; Sarah, Meade; Giorgia, Botta; Angela, Nebbioso; Jorg, Schemies; Manfred, Jung; Aleksey G, Kazantsev; Manel, Esteller; Mario F, Fraga; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 674-677 - issn: 1860-7179 - wos: WOS:000277725100005 (47) - scopus: 2-s2.0-77951697156 (46)

11573/229552 - 2010 - Nitric oxide determines mesodermic differentiation of mouse embryonic stem cells by activating class IIa histone deacetylases: potential therapeutic implications in a mouse model of hindlimb ischemia
Spallotta, F; Rosati, J; Straino, S; Nanni, S; Grasselli, A; Ambrosino, V; Rotili, Dante; Valente, Sergio; Farsetti, A; Mai, Antonello; Capogrossi, Mc; Gaetano, C; Illi, B. - 01a Articolo in rivista
rivista: STEM CELLS (Alphamed Press Incorporated:1 Prestige Place, Suite 290:Miamisburg, OH 45342:(937)291-2355, EMAIL: alphamedpress@alphamedpress.com, INTERNET: http://www.alphamedpress.com, Fax: (937)291-4229) pp. 431-442 - issn: 1066-5099 - wos: WOS:000277093700006 (48) - scopus: 2-s2.0-77950581254 (47)

11573/229551 - 2009 - Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence
Andrea, Savarino; Mai, Antonello; Sandro, Norelli; Sary El, Daker; Valente, Sergio; Rotili, Dante; Lucia, Altucci; Palamara, Anna Teresa; Enrico, Garaci - 01a Articolo in rivista
rivista: RETROVIROLOGY (London : BioMed Central) pp. 52-52 - issn: 1742-4690 - wos: WOS:000267430700001 (96) - scopus: 2-s2.0-67649259174 (97)

11573/13145 - 2009 - Chiral HPLC separation and absolute configuration of novel S-DABO derivatives.
Cirilli, R; Ferretti, R; La Torre, F; Borioni, A; Fares, V; Camalli, M; Faggi, C; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
rivista: CHIRALITY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 604-612 - issn: 0899-0042 - wos: WOS:000267250300007 (10) - scopus: 2-s2.0-67649403720 (11)

11573/456128 - 2009 - Reactions of 6-benzyl-5-methyl-2-(methylsulfanyl)pyrimidin-4(3H)-one with aliphatic and aliphatic-aromatic amines
I. A., Novakov; B. S., Orlinson; Mai, Antonello; Artico, Marino; Rotili, Dante; M. B., Navrotskii; E. A., Gordeeva; E. N., Savel'ev - 01a Articolo in rivista
rivista: RUSSIAN JOURNAL OF ORGANIC CHEMISTRY (pubblicata da: MAIK NAUKA/INTERPERIODICA, C/O KLUWER ACADEMIC-PLENUM PUBLISHERS, 233 SPRING ST, NEW YORK, USA, NY, 10013-1578) pp. 773-776 - issn: 1070-4280 - wos: WOS:000266829300021 (5) - scopus: 2-s2.0-67049164618 (3)

11573/360909 - 2009 - Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.
Lara, E; Mai, Antonello; Calvanese, V; Altucci, L; Lopez Nieva, P; Martinez Chantar, Ml; Varela Rey, M; Rotili, Dante; Nebbioso, A; Ropero, S; Montoya, G; Oyarzabal, J; Velasco, S; Serrano, M; Witt, M; Villar Garea, A; Inhof, A; Mato, Jm; Esteller, M; Fraga, Mf - 01a Articolo in rivista
rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 781-791 - issn: 0950-9232 - wos: WOS:000263320000001 (216) - scopus: 2-s2.0-60149091562 (235)

11573/456126 - 2009 - Stereoselective synthesis of 2-substituted 6-[1-(2,6-difluorophenyl)ethyl]-5-methylpyrimidin-4(3H)-ones.
Mai, Antonello; Artico, Marino; Rotili, Dante; Novakov, Ia; Orlinson, Bs; Navrotskii, Mb; Eremiichuk, As; Gordeeva, E. A. - 01a Articolo in rivista
rivista: RUSSIAN JOURNAL OF ORGANIC CHEMISTRY (pubblicata da: MAIK NAUKA/INTERPERIODICA, C/O KLUWER ACADEMIC-PLENUM PUBLISHERS, 233 SPRING ST, NEW YORK, USA, NY, 10013-1578) pp. 1531-1534 - issn: 1070-4280 - wos: WOS:000271810500019 (1) - scopus: 2-s2.0-70450201365 (0)

11573/361722 - 2009 - Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases
Mai, Antonello; Rotili, Dante; Tarantino, Domenico; Angela, Nebbioso; Sabrina, Castellano; Gianluca, Sbardella; Marc, Tini; Lucia, Altucci - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 1132-1135 - issn: 0960-894X - wos: WOS:000263295200021 (65) - scopus: 2-s2.0-59749103028 (70)

11573/442678 - 2009 - Histone deacetylase inhibitors and neurodegenerative disorders: Holding the promise
Mai, Antonello; Rotili, Dante; Valente, Sergio; Aleksey, Kazantsev - 01a Articolo in rivista
rivista: CURRENT PHARMACEUTICAL DESIGN (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 3940-3957 - issn: 1381-6128 - wos: WOS:000271385600003 (69) - scopus: 2-s2.0-70649108817 (70)

11573/434973 - 2009 - Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes.
Nebbioso, A; Manzo, F; Miceli, M; Conte, M; Manente, L; Baldi, A; De Luca, A; Rotili, Dante; Valente, Sergio; Mai, Antonello; Usiello, A; Gronemeyer, H; Altucci, L. - 01a Articolo in rivista
rivista: EMBO REPORTS (Oxford : Oxford University Press, 2000-) pp. 776-782 - issn: 1469-221X - wos: WOS:000267599700022 (118) - scopus: 2-s2.0-67650083046 (120)

11573/227010 - 2009 - Non-cancer uses of histone deacetylase inhibitors: effects on infectious diseases and β-hemoglobinopathies
Rotili, Dante; Simonetti, Giovanna; A., Savarino; Palamara, Anna Teresa; Migliaccio, A. R.; Mai, Antonello - 01a Articolo in rivista
rivista: CURRENT TOPICS IN MEDICINAL CHEMISTRY (Hilversum : Bentham Science Publishers) pp. 272-291 - issn: 1568-0266 - wos: WOS:000265798300006 (37) - scopus: 2-s2.0-65449142086 (47)

11573/361898 - 2008 - Histone deacetylase inhibitors and hemoglobin F induction in beta-thalassemia
A. R., Migliaccio; Rotili, Dante; A., Nebbioso; G., Atweh; Mai, Antonello - 01a Articolo in rivista
rivista: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 2341-2347 - issn: 1357-2725 - wos: WOS:000259134100002 (13) - scopus: 2-s2.0-48349094044 (17)

11573/363940 - 2008 - Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases
Gianluca, Sbardella; Sabrina, Castellano; Caterina, Vicidomini; Rotili, Dante; Angela, Nebbioso; Marco, Miceli; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 2788-2792 - issn: 0960-894X - wos: WOS:000255444300005 (82) - scopus: 2-s2.0-42949089945 (88)

11573/358405 - 2008 - Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling
Illi, B.; Dello Russo, Claudio; Colussi, C.; Rosati, J.; Pallaoro, M.; Spallotta, F.; Rotili, Dante; Valente, Sergio; Ragone, G.; Martelli, F.; Biglioli, P.; Steinkuhler, C.; Gallinari, P.; Mai, Antonello; Capogrossi, M. C.; Gaetano, C. - 01a Articolo in rivista
rivista: CIRCULATION RESEARCH (Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320 PRimo editore: Baltimore, Md. : Grune & Stratton, c1953-) pp. 51-58 - issn: 0009-7330 - wos: WOS:000252217400009 (96) - scopus: 2-s2.0-37849010584 (100)

11573/363936 - 2008 - Novel uracil-based 2-aminoanilide and 2-aminoanilide-like derivatives: Histone deacetylase inhibition and in-cell activities
Mai, Antonello; Andrea, Perrone; Angela, Nebbioso; Rotili, Dante; Valente, Sergio; Maria, Tardugno; Silvio, Massa; Floriana De, Bellis; Lucia, Altucci - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 2530-2535 - issn: 0960-894X - wos: WOS:000255246400002 (25) - scopus: 2-s2.0-41849089386 (28)

11573/363647 - 2008 - 5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile.
Nawrozkij, Mb; Rotili, Dante; Tarantino, Domenico; Botta, G; Eremiychuk, As; Musmuca, Ira; Ragno, Rino; Samuele, A; Zanoli, S; Armand Ugón, M; Clotet Codina, I; Novakov, Ia; Orlinson, Bs; Maga, G; Esté, Ja; Artico, Marino; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4641-4652 - issn: 0022-2623 - wos: WOS:000258289800033 (54) - scopus: 2-s2.0-49449113636 (57)

11573/365241 - 2008 - Class II-selective histone deacetylase inhibitors. Part 2: Alignment-independent GRIND 3-D QSAR, homology and docking studies
Ragno, Rino; Silvia, Simeoni; Rotili, Dante; Antonella, Caroli; Giorgia, Botta; Gerald, Brosch; Silvio, Massa; Mai, Antonello - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 621-632 - issn: 0223-5234 - wos: WOS:000254777400019 (38) - scopus: 2-s2.0-40049110686 (46)

11573/362098 - 2008 - Substrate-induced stable enzyme-inhibitor complex formation allows tight binding of novel 2-aminopyrimidin-4(3H)-ones to drug-resistant HIV-1 reverse transcriptase mutants.
Samuele, A; Facchini, M; Rotili, Dante; Mai, Antonello; Artico, Marino; Armand Ugón, M; Esté, Ja; Maga, G. - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1412-1418 - issn: 1860-7179 - wos: WOS:000259628300014 (9) - scopus: 2-s2.0-54849438319 (9)

11573/363321 - 2007 - Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains
Mai, Antonello; Artico, Marino; Rotili, Dante; Tarantino, Domenico; Clotet Codina, I; Armand Ugón, M; Ragno, Rino; Simeoni, S; Sbardella, G; Nawrozkij, M. B.; Samuele, A; Maga, G; Esté, J. A. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5412-5424 - issn: 0022-2623 - wos: WOS:000250557100019 (58) - scopus: 2-s2.0-35848949355 (62)

11573/362130 - 2007 - Identification of two new synthetic histone deacetylase inhibitors that modulate globin gene expression in erythroid cells from healthy donors and patients with thalassemia
Mai, Antonello; K., Jelicic; Rotili, Dante; A., Di Noia; E., Alfani; Valente, Sergio; L., Altucci; A., Nebbioso; S., Massa; R., Galanello; G., Brosch; A. R., Migliaccio; G., Migliaccio - 01a Articolo in rivista
rivista: MOLECULAR PHARMACOLOGY (American Society for Pharmacology and Experimental Therapeutics:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7024, EMAIL: pstoute@aspet.org, INTERNET: http://www.aspet.org, Fax: (301)634-7099) pp. 1111-1123 - issn: 0026-895X - wos: WOS:000250385300004 (29) - scopus: 2-s2.0-35548933854 (30)

11573/365178 - 2007 - Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans
Mai, Antonello; Rotili, Dante; Massa, Silvio; Gerald, Brosch; Simonetti, Giovanna; Passariello, Claudio; Palamara, Anna Teresa - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 1221-1225 - issn: 0960-894X - wos: WOS:000244943300017 (79) - scopus: 2-s2.0-33846938126 (85)

11573/364545 - 2007 - Novel pyrrole-containing histone deacetylase inhibitors endowed with cytodifferentiation activity
Mai, Antonello; Valente, Sergio; Rotili, Dante; Silvio, Massa; Giorgia, Botta; Gerald, Brosch; Marco, Miceli; Angela, Nebbioso; Lucia, Altucci - 01a Articolo in rivista
rivista: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 1510-1522 - issn: 1357-2725 - wos: WOS:000248566700025 (14) - scopus: 2-s2.0-34447268739 (14)

11573/51617 - 2007 - Docking and 3-D QSAR Studies on SIRT2 Inhibitors: A GRID/GOLPE Approach on Different Series of Compounds.
Ragno, Rino; Mai, Antonello; Simeoni, Silvia; Caroli, Antonia; Rotili, Dante; Botta, Giorgia - 04a Atto di comunicazione a congresso
congresso: Frontiers in CNS and Oncology Medicinal Chemistry, ACS-EFMC (Siena, Italy)
libro: Frontiers in CNS and Oncology Medicinal Chemistry, ACS-EFMC - ()

11573/361993 - 2007 - Slow-, tight-binding HIV-1 reverse transcriptase non-nucleoside inhibitors highly active against drug-resistant mutants
Reynel, Cancio; Mai, Antonello; Rotili, Dante; Marino, Artico; Gianluca, Sbardella; Imma Clotet, Codina; José A, Este; Emmanuele, Crespan; Samantha, Zanoli; Ulrich, Hubscher; Silvio, Spadari; Giovanni, Maga - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 445-448 - issn: 1860-7179 - wos: WOS:000246011500006 (20) - scopus: 2-s2.0-34547939030 (22)

11573/362194 - 2007 - Histone deacetylase inhibitors may reduce pathogenicity and virulence in Candida albicans
Simonetti, Giovanna; Passariello, Claudio; Rotili, Dante; Mai, Antonello; Enrico, Garaci; Palamara, Anna Teresa - 01a Articolo in rivista
rivista: FEMS YEAST RESEARCH (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1371-1380 - issn: 1567-1356 - wos: WOS:000250298000018 (41) - scopus: 2-s2.0-35448985401 (42)

11573/362375 - 2006 - Analytical and semipreparative high performance liquid chromatography separation of stereoisomers of novel 3,4-dihydropyrimidin-4(3H)-one derivatives on the immobilised amylose-based Chiralpack IA chiral stationary phase.
Cirilli, R; Ferretti, R; Gallinella, B; La Torre, F; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
rivista: JOURNAL OF SEPARATION SCIENCE (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 1399-1406 - issn: 1615-9306 - wos: WOS:000239291200011 (27) - scopus: 2-s2.0-33746470231 (29)

11573/358996 - 2006 - Small-Molecule Inhibitors of Histone Acetyltransferase Activity: Identification and Biological Properties
Mai, A; Rotili, D.; Tarantino, D; Ornaghi, P; Tosi, F; Vicidomini, C; Sbardella, G; Nebbioso, A; Miceli, M; Altucci, L; Filetici, P - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6897-6907 - issn: 0022-2623 - wos: WOS:000241894000031 (121) - scopus: 2-s2.0-33750989910 (129)

11573/12854 - 2006 - Identification of small molecules inhibitors of GCN5 histone acetyltransferase activity
Mai, Antonello; Rotili, Dante; Ornaghi, P; Tosi, F; Vicidomini, C; Sbardella, G; Nebbioso, A; Altucci, L; Filetici, P. - 01a Articolo in rivista
rivista: ARKIVOC (ARKAT USA INC, C/O ALAN R KATRITZKY, UNIV FLORIDA, DEPT CHEMISTRY, PO BOX 117200, GAINESVILLE, USA, FL, 32611) pp. 24-37 - issn: 1551-7004 - wos: WOS:000242574600004 (6) - scopus: 2-s2.0-33744470562 (7)

11573/363353 - 2006 - Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors
Mai, Antonello; Silvio, Massa; Rotili, Dante; Silvia, Simeoni; Ragno, Rino; Giorgia, Botta; Angela, Nebbioso; Marco, Miceli; Lucia, Altucci; Gerald, Brosch - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6046-6056 - issn: 0022-2623 - wos: WOS:000240826200019 (59) - scopus: 2-s2.0-33749258885 (57)

11573/366703 - 2006 - One-Pot, High Yielding Synthesis of Novel Dihydrothiazolo[3,2-a]pyrimidinones
Rotili, Dante; Mai, Antonello; Ambrogio, I; G., Fabrizi - 01a Articolo in rivista
rivista: SYNTHETIC COMMUNICATIONS (New York, NY : Taylor & Francis New York, NY: Marcel Dekker Incorporated) pp. 495-500 - issn: 0039-7911 - wos: WOS:000234819600013 (0) - scopus: 2-s2.0-31744445689 (1)

11573/363623 - 2006 - 6-Alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): Novel Regulators of Cell Differentiation and Proliferation
Sbardella, G; Bartolini, S; Castellano, S; Artico, Marino; Paesano, N; Rotili, Dante; Spadafora, C; Mai, Antonello - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1073-1080 - issn: 1860-7179 - wos: WOS:000202946300006 (13) - scopus: 2-s2.0-33750284393 (14)

11573/526020 - 2005 - Histone Deacetylation in Epigenetics: An Attractive Target for Anticancer Therapy
Mai, Antonello; Massa, S; Rotili, Dante; Cerbara, I; Valente, Sergio; Pezzi, R; Simeoni, S; Ragno, Rino - 01a Articolo in rivista
rivista: MEDICINAL RESEARCH REVIEWS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 261-309 - issn: 0198-6325 - wos: WOS:000228224900001 (302) - scopus: 2-s2.0-16844362441 (320)

11573/364675 - 2005 - Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides
Mai, Antonello; Silvio, Massa; Riccardo, Pezzi; Silvia, Simeoni; Rotili, Dante; Angela, Nebbioso; Annamaria, Scognamiglio; Lucia, Altucci; Peter, Loidl; Gerald, Brosch - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3344-3353 - issn: 0022-2623 - wos: WOS:000228871700031 (187) - scopus: 2-s2.0-20944435415 (195)

11573/364679 - 2005 - Exploring the connection unit in the HDAC inhibitor pharmacophore model: Novel uracil-based hydroxamates
Mai, Antonello; Silvio, Massa; Rotili, Dante; Riccardo, Pezzi; Patrizia, Bottoni; Roberto, Scatena; Joachim, Meraner; Gerald, Brosch - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 4656-4661 - issn: 0960-894X - wos: WOS:000232465900002 (45) - scopus: 2-s2.0-25144444434 (48)

11573/363627 - 2005 - A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast
Prisca, Ornaghi; Rotili, Dante; Gianluca, Sbardella; Mai, Antonello; Patrizia, Filetici - 01a Articolo in rivista
rivista: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited -London ; New York : Pergamon Press, 1958-) pp. 911-917 - issn: 0006-2952 - wos: WOS:000231663100011 (36) - scopus: 2-s2.0-23744453206 (38)

11573/364674 - 2005 - 6-[1-(2,6-difluorophenyl)ethyl]pyrimidinones antagonize cell proliferation and induce cell differentiation by inhibiting (a nontelomeric) endogenous reverse transcriptase
Sara, Bartolini; Mai, Antonello; Artico, Marino; Nicola, Paesano; Rotili, Dante; Corrado, Spadafora; Gianluca, Sbardella - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6776-6778 - issn: 0022-2623 - wos: WOS:000233017300003 (51) - scopus: 2-s2.0-27444434731 (51)

11573/189567 - 2004 - Synthesis and evaluation of sirtinol analogues as yeast Sir2 and human SIRT inhibitors
Pezzi, R.; Rotili, D.; Simeoni, S.; Ragno, Rino; Mariotti, Francesca Romana; Chiani, Francesco; Camilloni, Giorgio; Massa, S.; Mai, Antonello - 04a Atto di comunicazione a congresso
libro: XVIII International Symposium on Medicinal Chemistry - ()

11573/366839 - 2003 - Discovery of (Aryloxo propenyl)pyrrolyl Hydroxyamides as Selective Inhibitors of Class IIa Histone Deacetylase Homologue HD1-A
Mai, Antonello; Massa, S.; Pezzi, R.; Rotili, Dante; Loidl, P.; Brosch, G. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4826-4829 - issn: 0022-2623 - wos: WOS:000186347400004 (62) - scopus: 2-s2.0-0242362600 (66)

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