11573/1696800 - 2024 -
Enhancing sensitivity of triple-negative breast cancer to DNA-damaging therapy through chemical inhibition of the m6A methyltransferase METTL3 Cesaro, Bianca; Iaiza, Alessia; Piscopo, Fabio; Tarullo, Marco; Cesari, Eleonora; Rotili, Dante; Mai, Antonello; Diana, Alberto; Londero, Michela; Del Giacco, Luca; Masetti, Riccardo; Di Leone, Alba; Naro, Chiara; Masciarelli, Silvia; Fontemaggi, Giulia; Sette, Claudio; Fazi, Francesco; Fatica, Alessandro - 01f Lettera, Nota
rivista: CANCER COMMUNICATIONS (London: BioMed Central) pp. 282-286 - issn: 2523-3548 - wos: WOS:001125441200001 (1) - scopus: 2-s2.0-85179653539 (0)
11573/1712923 - 2024 -
M6A reduction relieves FUS-associated ALS granules Di Timoteo, Gaia; Giuliani, Andrea; Setti, Adriano; Biagi, Martina C.; Lisi, Michela; Santini, Tiziana; Grandioso, Alessia; Mariani, Davide; Castagnetti, Francesco; Perego, Eleonora; Zappone, Sabrina; Lattante, Serena; Sabatelli, Mario; Rotili, Dante; Vicidomini, Giuseppe; Bozzoni, Irene - 01a Articolo in rivista
rivista: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. - - issn: 2041-1723 - wos: (0) - scopus: 2-s2.0-85195950842 (0)
11573/1710159 - 2024 -
Uracil- and Pyridine-Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells Fiorentino, Francesco; Fabbrizi, Emanuele; Raucci, Alessia; Noce, Beatrice; Fioravanti, Rossella; Valente, Sergio; Paolini, Chantal; De Maria, Ruggero; Steinkühler, Christian; Gallinari, Paola; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. - - issn: 1860-7187 - wos: WOS:001214621100001 (0) - scopus: 2-s2.0-85191719139 (0)
11573/1711772 - 2024 -
(Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling Golovina, Anastasia; Proia, Eleonora; Fiorentino, Francesco; Yunin, Maxim; Kasatkina, Maria; Zigangirova, Nailya; Soloveva, Anna; Sysolyatina, Elena; Ermolaeva, Svetlana; Novikov, Roman; Silonov, Sergei; Pushkin, Sergei; Mladenović, Milan; Isakova, Julia; Belik, Albina; Nawrozkij, Maxim; Rotili, Dante; Ragno, Rino; Ivanov, Roman - 01a Articolo in rivista
rivista: ACS INFECTIOUS DISEASES (Washington, DC : American Chemical Society, 2015-) pp. 2127-2150 - issn: 2373-8227 - wos: WOS:001228938600001 (0) - scopus: 2-s2.0-85194084452 (0)
11573/1710806 - 2024 -
The α-tubulin acetyltransferase ATAT1: structure, cellular functions, and its emerging role in human diseases Iuzzolino, Angela; Pellegrini, Francesca Romana; Rotili, Dante; Degrassi, Francesca; Trisciuoglio, Daniela - 01g Articolo di rassegna (Review)
rivista: CELLULAR AND MOLECULAR LIFE SCIENCES (Basel: Birkhäuser 1997-) pp. - - issn: 1420-9071 - wos: WOS:001207262200003 (0) - scopus: 2-s2.0-85191030912 (0)
11573/1710803 - 2024 -
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection Maure, Alexandra; Lawarée, Emeline; Fiorentino, Francesco; Pawlik, Alexandre; Gona, Saideep; Giraud-Gatineau, Alexandre; Eldridge, Matthew J. G.; Danckaert, Anne; Hardy, David; Frigui, Wafa; Keck, Camille; Gutierrez, Claude; Neyrolles, Olivier; Aulner, Nathalie; Mai, Antonello; Hamon, Mélanie; Barreiro, Luis B.; Brodin, Priscille; Brosch, Roland; Rotili, Dante; Tailleux, Ludovic - 01a Articolo in rivista
rivista: PLOS BIOLOGY (San Francisco, CA : Public Library of Science, c2003-) pp. - - issn: 1545-7885 - wos: WOS:001214097100008 (0) - scopus: 2-s2.0-85191815044 (0)
11573/1703580 - 2024 -
Specific inhibitors of mitochondrial deacylase sirtuin 4 endowed with cellular activity Pannek, M.; Alhalabi, Z.; Tomaselli, D.; Menna, M.; Fiorentino, F.; Robaa, D.; Weyand, M.; Puhlmann, M.; Tomassi, S.; Barreca, F.; Tafani, M.; Zaganjor, E.; Haigis, M. C.; Sippl, W.; Rotili, D.; Mai, A.; Steegborn, C. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 1843-1860 - issn: 1520-4804 - wos: WOS:001160605300001 (2) - scopus: 2-s2.0-85184667987 (2)
11573/1703586 - 2024 -
Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer Pecci, Valeria; Troisi, Fabiola; Aiello, Aurora; De Martino, Sara; Carlino, Angela; Fiorentino, Vincenzo; Ripoli, Cristian; Rotili, Dante; Pierconti, Francesco; Martini, Maurizio; Porru, Manuela; Pinto, Francesco; Mai, Antonello; Bassi, Pier Francesco; Grassi, Claudio; Gaetano, Carlo; Pontecorvi, Alfredo; Strigari, Lidia; Farsetti, Antonella; Nanni, Simona - 01a Articolo in rivista
rivista: CANCER CELL INTERNATIONAL ([London]: BioMed Central.) pp. - - issn: 1475-2867 - wos: WOS:001156914300001 (0) - scopus: 2-s2.0-85184414355 (0)
11573/1714195 - 2024 -
Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1 Spizzichino, Sharon; Di Fonzo, Federica; Marabelli, Chiara; Tramonti, Angela; Chaves-Sanjuan, Antonio; Parroni, Alessia; Boumis, Giovanna; Liberati, Francesca Romana; Paone, Alessio; Montemiglio, Linda Celeste; Ardini, Matteo; Jakobi, Arjen J.; Bharadwaj, Alok; Swuec, Paolo; Tartaglia, Gian Gaetano; Paiardini, Alessandro; Contestabile, Roberto; Mai, Antonello; Rotili, Dante; Fiorentino, Francesco; Macone, Alberto; Giorgi, Alessandra; Tria, Giancarlo; Rinaldo, Serena; Bolognesi, Martino; Giardina, Giorgio; Cutruzzola, Francesca - 01a Articolo in rivista
rivista: MOLECULAR CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. - - issn: 1097-2765 - wos: (0) - scopus: (0)
11573/1661959 - 2023 -
Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells Ansari, Mohammad Salik Zeya; Stagni, Venturina; Iuzzolino, Angela; Rotili, Dante; Mai, Antonello; Del Bufalo, Donatella; Lavia, Patrizia; Degrassi, Francesca; Trisciuoglio, Daniela - 01a Articolo in rivista
rivista: CANCER GENE THERAPY (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 124-136 - issn: 0929-1903 - wos: WOS:000854955000001 (8) - scopus: 2-s2.0-85138300847 (8)
11573/1673946 - 2023 -
Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery Aventaggiato, Michele; Barreca, Federica; Vitiello, Laura; Vespa, Simone; Valente, Sergio; Rotili, Dante; Mai, Antonello; Lotti, Lavinia Vittoria; Sansone, Luigi; Russo, Matteo A.; Bizzarri, Mariano; Ferretti, Elisabetta; Tafani, Marco - 01a Articolo in rivista
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000947513100001 (2) - scopus: 2-s2.0-85149752388 (3)
11573/1694442 - 2023 -
Hydroxamate-based compounds are potent inhibitors of Toxoplasma gondii HDAC biological activity Boissavy, Tom; Rotili, Dante; Mouveaux, Thomas; Roger, Emmanuel; Aliouat, El Moukthar; Pierrot, Christine; Valente, Sergio; Mai, Antonello; Gissot, Mathieu - 01a Articolo in rivista
rivista: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (American Society for Microbiology:PO Box 11127:Birmingham, AL 35201:(800)633-4931, (205)995-1567, EMAIL: asm.nonmembers.subs@ebsco.com, INTERNET: http://www.asm.org, Fax: (205)995-1588) pp. e0066123- - issn: 0066-4804 - wos: WOS:001090003100001 (1) - scopus: (0)
11573/1674091 - 2023 -
GreenMedChem- the challenge in the next decade toward eco-friendly compounds and processes in drug design Castiello, Carola; Junghanns, Pierre; Mergel, Annika; Jacob, Claus; Ducho, Christian; Valente, Sergio; Rotili, Dante; Fioravanti, Rossella; Zwergel, Clemens; Mai, Antonello - 01g Articolo di rassegna (Review)
rivista: GREEN CHEMISTRY (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 2109-2169 - issn: 1463-9262 - wos: WOS:000946579600001 (19) - scopus: 2-s2.0-85150432512 (19)
11573/1677023 - 2023 -
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection Fabbrizi, Emanuele; Fiorentino, Francesco; Carafa, Vincenzo; Altucci, Lucia; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 852- - issn: 2073-4409 - wos: WOS:000957394600001 (7) - scopus: 2-s2.0-85151108488 (7)
11573/1669898 - 2023 -
Pyrimidine thioethers: A novel class of antidepressant agents, endowed with anxiolytic, performance enhancing and nootropic activity Fioravanti, Rossella; Proia, Eleonora; Tyurenkov, Ivan N; Kurkin, Denis V; Bakulin, Dmitry A; Kovalev, Nikolay S; Sheikin, Dmitry S; Kirillov, Ivan A; Nawrozkij, Maxim B; Vernigora, Andrey A; Brunilina, Leila L; Fiorentino, Francesco; Mladenović, Milan; Rotili, Dante; Ragno, Rino - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ([Paris] : Elsevier, [198?]-) pp. 114902- - issn: 1768-3254 - wos: WOS:000993134500001 (0) - scopus: 2-s2.0-85141941686 (2)
11573/1694364 - 2023 -
State of the art of carbonic anhydrase activators Fiorentino, Francesco; Carta, Fabrizio; Rotili, Dante; Mai, Antonello; Supuran, Claudiu T - 01m Editorial/Introduzione in rivista
rivista: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 2025-2028 - issn: 1756-8919 - wos: WOS:001081530900001 (3) - scopus: 2-s2.0-85177103741 (2)
11573/1689870 - 2023 -
The role of structural biology in the design of sirtuin activators Fiorentino, Francesco; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
rivista: CURRENT OPINION IN STRUCTURAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 102666- - issn: 0959-440X - wos: WOS:001057837700001 (3) - scopus: 2-s2.0-85169440750 (3)
11573/1669899 - 2023 -
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey Fiorentino, Francesco; Menna, Martina; Rotili, Dante; Valente, Sergio; Mai, Antonello - 01g Articolo di rassegna (Review)
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 1654-1677 - issn: 1520-4804 - wos: WOS:000932489700001 (11) - scopus: 2-s2.0-85147012551 (17)
11573/1677022 - 2023 -
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII Fiorentino, Francesco; Nocentini, Alessio; Rotili, Dante; Supuran, Claudiu T; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 2188147- - issn: 1475-6366 - wos: WOS:000949495200001 (4) - scopus: 2-s2.0-85150225921 (3)
11573/1677024 - 2023 -
Native mass spectrometry-directed drug discovery: Recent advances in investigating protein function and modulation Fiorentino, Francesco; Rotili, Dante; Mai, Antonello - 01g Articolo di rassegna (Review)
rivista: DRUG DISCOVERY TODAY (Elsevier Science Limited Trends Journals:PO Box 331, Haywards Heath RH16 3FG United Kingdom:011 44 1444 475651, EMAIL: ct.subs@rbi.co.uk, Fax: 011 44 1444 445423) pp. 103548- - issn: 1359-6446 - wos: WOS:000955583400001 (4) - scopus: 2-s2.0-85150033652 (4)
11573/1681512 - 2023 -
First-in-class selective inhibitors of the lysine acetyltransferase KAT8 Fiorentino, Francesco; Sementilli, Sara; Menna, Martina; Turrisi, Federica; Tomassi, Stefano; Pellegrini, Francesca Romana; Iuzzolino, Angela; D'acunzo, Francesca; Feoli, Alessandra; Wapenaar, Hannah; Taraglio, Sophie; Fraschetti, Caterina; Del Bufalo, Donatella; Sbardella, Gianluca; Dekker, Frank J.; Paiardini, Alessandro; Trisciuoglio, Daniela; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 6591-6616 - issn: 1520-4804 - wos: WOS:000988858800001 (2) - scopus: 2-s2.0-85159627845 (3)
11573/1695097 - 2023 -
BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress Marchant, Vanessa; Trionfetti, Flavia; Tejedor-Santamaria, Lucia; Rayego-Mateos, Sandra; Rotili, Dante; Bontempi, Giulio; Domenici, Alessandro; Menè, Paolo; Mai, Antonello; Martín-Cleary, Catalina; Ortiz, Alberto; Ramos, Adrian M.; Strippoli, Raffaele; Ruiz-Ortega, Marta - 01a Articolo in rivista
rivista: ANTIOXIDANTS (Basel: MDPI) pp. 1-19 - issn: 2076-3921 - wos: WOS:001137851500001 (0) - scopus: 2-s2.0-85180466019 (0)
11573/1669922 - 2023 -
Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells Negri, Aide; Marozzi, Marina; Trisciuoglio, Daniela; Rotili, Dante; Mai, Antonello; Rizzi, Federica - 01a Articolo in rivista
rivista: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Abingdon Oxfordshire United Kingdom: Taylor & Francis
London: Gordon and Breach, 2002-) pp. 2163242- - issn: 1475-6374 - wos: WOS:000911853100001 (5) - scopus: 2-s2.0-85146193316 (7)
11573/1658358 - 2023 -
Chemically diverse S. mansoni HDAC8 inhibitors reduced viability in worm larval and adult stages Noce, Beatrice; Di Bello, Elisabetta; Zwergel, Clemens; Fioravanti, Rossella; Valente, Sergio; Rotili, Dante; Masotti, Andrea; Ansari, Mohammad Salik Zeya; Trisciuoglio, Daniela; Chakrabarti, Alokta; Romier, Christophe; Robaa, Dina; Sippl, Wolfgang; Jung, Manfred; Häberli, Cécile; Keiser, Jennifer; Mai, Antonello - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. - - issn: 1860-7179 - wos: WOS:000879912800001 (4) - scopus: 2-s2.0-85141693563 (4)
11573/1689849 - 2023 -
Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa. Scribani Rossi, C; Eckartt, K; Scarchilli, E; Angeli, S; Price-Whelan, A; Di Matteo, A; Chevreuil, M; Raynal, B; Arcovito, A; Giacon, N; Fiorentino, F; Rotili, D; Mai, A; Espinosa-Urgel, M; Cutruzzola', F; Dietrich, Lep; Paone, A; Paiardini, A; Rinaldo, S - 01a Articolo in rivista
rivista: MICROBIOLOGICAL RESEARCH (Urban & Fischer Verlag Jena:Postfach 100537, D-07705 Jena Germany:011 49 3641 626430, EMAIL: journals@urbanfischer.de, INTERNET: http://www.urbanfischer.de, Fax: 011 49 3641 626500) pp. 127498- - issn: 0944-5013 - wos: WOS:001097478000001 (0) - scopus: 2-s2.0-85173505521 (0)
11573/1696065 - 2023 -
HDAC1-3 inhibition increases SARS-CoV-2 replication and productive infection in lung mesothelial and epithelial cells Trionfetti, Flavia; Alonzi, Tonino; Bontempi, Giulio; Terri, Michela; Battistelli, Cecilia; Montaldo, Claudia; Repele, Federica; Rotili, Dante; Valente, Sergio; Zwergel, Clemens; Matusali, Giulia; Maggi, Fabrizio; Goletti, Delia; Tripodi, Marco; Mai, Antonello; Strippoli, Raffaele - 01a Articolo in rivista
rivista: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (Lausanne : Frontiers Media SA, 2011-) pp. - - issn: 2235-2988 - wos: WOS:001130489700001 (1) - scopus: (0)
11573/1694558 - 2023 -
SIRT6 Protects Against Lipopolysaccharide-Induced Inflammation in Human Pulmonary Lung Microvascular Endothelial Cells Wang, Jinping; Luo, Jinque; Rotili, Dante; Mai, Antonello; Steegborn, Clemens; Xu, Suowen; Jin, Zheng Gen - 01a Articolo in rivista
rivista: INFLAMMATION (Springer Nature
New York, NY: Plenum Press) pp. - - issn: 0360-3997 - wos: WOS:001082492200001 (3) - scopus: 2-s2.0-85173797364 (3)
11573/1694680 - 2023 -
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase Zhou, Jujun; Deng, Youchao; Iyamu, Iredia D; Horton, John R; Yu, Dan; Hajian, Taraneh; Vedadi, Masoud; Rotili, Dante; Mai, Antonello; Blumenthal, Robert M; Zhang, Xing; Huang, Rong; Cheng, Xiaodong - 01a Articolo in rivista
rivista: ACS CHEMICAL BIOLOGY (Washington, D.C. : American Chemical Society, c2006-) pp. 734-745 - issn: 1554-8937 - wos: WOS:000936764500001 (2) - scopus: 2-s2.0-85148863880 (2)
11573/1664753 - 2023 -
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence Zhou, Jujun; Horton, John R.; Menna, Martina; Fiorentino, Francesco; Ren, Ren; Yu, Dan; Hajian, Taraneh; Vedadi, Masoud; Mazzoccanti, Giulia; Ciogli, Alessia; Weinhold, Elmar; Hüben, Michael; Blumenthal, Robert M.; Zhang, Xing; Mai, Antonello; Rotili, Dante; Cheng, Xiaodong - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 934-950 - issn: 0022-2623 - wos: WOS:000907749800001 (2) - scopus: 2-s2.0-85145455635 (2)
11573/1684985 - 2023 -
Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells Zwergel, Clemens; Aventaggiato, Michele; Garbo, Sabrina; Di Bello, Elisabetta; Fassari, Bruno; Noce, Beatrice; Castiello, Carola; Lambona, Chiara; Barreca, Federica; Rotili, Dante; Fioravanti, Rossella; Schmalz, Thomas; Weyand, Michael; Niedermeier, Amelie; Tripodi, Marco; Colotti, Gianni; Steegborn, Clemens; Battistelli, Cecilia; Tafani, Marco; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9622-9641 - issn: 0022-2623 - wos: WOS:001027732800001 (7) - scopus: 2-s2.0-85165671509 (7)
11573/1658360 - 2022 -
Histone lysine demethylase inhibition reprograms prostate cancer metabolism and mechanics Chianese, Ugo; Papulino, Chiara; Passaro, Eugenia; Evers, Tom Mj; Babaei, Mehrad; Toraldo, Antonella; De Marchi, Tommaso; Niméus, Emma; Carafa, Vincenzo; Nicoletti, Maria Maddalena; Del Gaudio, Nunzio; Iaccarino, Nunzia; Randazzo, Antonio; Rotili, Dante; Mai, Antonello; Cappabianca, Salvatore; Mashaghi, Alireza; Ciardiello, Fortunato; Altucci, Lucia; Benedetti, Rosaria - 01a Articolo in rivista
rivista: MOLECULAR METABOLISM (Amsterdam : Elsevier) pp. 101561- - issn: 2212-8778 - wos: WOS:000844094200002 (2) - scopus: 2-s2.0-85136069603 (3)
11573/1618409 - 2022 -
Multimodal evaluation of 19F-BPA internalization in pancreatic cancer cells for boron capture and proton therapy potential applications Ciardiello, A.; Altierix, S.; Ballarini, F.; Bocci, V.; Bortolussi, S.; Cansolino, L.; Carlotti, D.; Ciocca, M.; Faccini, R.; Facoetti, A.; Ferrari, C.; Ficcadenti, L.; Furfaro, E.; Giagu, S.; Iacoangeli, F.; Macioce, G.; Mancini-Terracciano, C.; Messina, A.; Milazzo, L.; Pacifico, S.; Piccolella, S.; Postuma, I.; Rotili, D.; Vercesi, V.; Voena, C.; Vulcano, F.; Capuani, S. - 01a Articolo in rivista
rivista: PHYSICA MEDICA (UK: Elsevier
Pisa: Istituti Editoriali e Poligrafici Internazionali.
Pisa Italy: Giardini Editori Stampatori) pp. 75-84 - issn: 1120-1797 - wos: WOS:000750944300002 (3) - scopus: 2-s2.0-85122230962 (3)
11573/1650772 - 2022 -
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni Di Bello, Elisabetta; Noce, Beatrice; Fioravanti, Rossella; Zwergel, Clemens; Valente, Sergio; Rotili, Dante; Fianco, Giulia; Trisciuoglio, Daniela; Mourão, Marina M; Sales, Policarpo; Lamotte, Suzanne; Prina, Eric; Späth, Gerald F; Häberli, Cécile; Keiser, Jennifer; Mai, Antonello - 01a Articolo in rivista
rivista: ACS INFECTIOUS DISEASES (Washington, DC : American Chemical Society, 2015-) pp. 1356-1366-1366 - issn: 2373-8227 - wos: WOS:000819851400001 (15) - scopus: 2-s2.0-85134360722 (15)
11573/1657352 - 2022 -
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5 Fiorentino, F.; Castiello, C.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9580-9606 - issn: 0022-2623 - wos: WOS:000835071900001 (18) - scopus: 2-s2.0-85135378527 (21)
11573/1638052 - 2022 -
Sirtuin modulators: past, present, and future perspectives Fiorentino, Francesco; Mautone, Nicola; Menna, Martina; D'acunzo, Francesca; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
rivista: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. - - issn: 1756-8919 - wos: WOS:000797024400001 (0) - scopus: 2-s2.0-85131771683 (20)
11573/1628944 - 2022 -
Neuroprotective effects of PARP inhibitors in Drosophila models of Alzheimer’s disease Maggiore, Anna; Casale, Assunta Maria; Toscanelli, Walter; Cappucci, Ugo; Rotili, Dante; Grieco, Maddalena; Gagné, Jean-Philippe; Poirier, Guy G.; D’Erme, Maria; Piacentini, Lucia - 01a Articolo in rivista
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000786053000001 (9) - scopus: 2-s2.0-85127837219 (10)
11573/1635728 - 2022 -
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models Menna, M.; Fiorentino, F.; Marrocco, B.; Lucidi, A.; Tomassi, S.; Cilli, D.; Romanenghi, M.; Cassandri, M.; Pomella, S.; Pezzella, M.; Del Bufalo, D.; Zeya Ansari, M. S.; Tomasevic, N.; Mladenovic, M.; Viviano, M.; Sbardella, G.; Rota, R.; Trisciuoglio, D.; Minucci, S.; Mattevi, A.; Rotili, D.; Mai, A. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000804176200002 (15) - scopus: 2-s2.0-85129352278 (15)
11573/1613297 - 2022 -
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription Minisini, Martina; Di Giorgio, Eros; Kerschbamer, Emanuela; Dalla, Emiliano; Faggiani, Massimo; Franforte, Elisa; Meyer-Almes, Franz-Josef; Ragno, Rino; Antonini, Lorenzo; Mai, Antonello; Fiorentino, Francesco; Rotili, Dante; Chinellato, Monica; Perin, Stefano; Cendron, Laura; Weichenberger, Christian X; Angelini, Alessandro; Brancolini, Claudio - 01a Articolo in rivista
rivista: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485
Editore precedente:
Information Retrieval ltd., London) pp. - - issn: 0305-1048 - wos: WOS:000764227300001 (12) - scopus: 2-s2.0-85127539205 (11)
11573/1622839 - 2022 -
A potent HDAC inhibitor blocks Toxoplasma gondii tachyzoite growth and profoundly disrupts parasite gene expression Mouveaux, T.; Rotili, D.; Boissavy, T.; Roger, E.; Pierrot, C.; Mai, A.; Gissot, M. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 106526- - issn: 0924-8579 - wos: WOS:000784446400008 (12) - scopus: 2-s2.0-85124124624 (11)
11573/1664310 - 2022 -
Modulation of virulence-associated traits in Aspergillus fumigatus by BET Inhibitor JQ1 Orekhova, Anastasia; De Angelis, Marta; Cacciotti, Andrea; Reverberi, Massimo; Rotili, Dante; Giorgi, Alessandra; Protto, Virginia; Bonincontro, Graziana; Fiorentino, Francesco; Zgoda, Victor; Mai, Antonello; Palamara, Anna Teresa; Simonetti, Giovanna - 01a Articolo in rivista
rivista: MICROORGANISMS (Basel : MDPI) pp. 1-19 - issn: 2076-2607 - wos: WOS:000895665300001 (1) - scopus: 2-s2.0-85144917834 (2)
11573/1541295 - 2022 -
90Y-DOTA-nimotuzumab: synthesis of a promising β⁻ radiopharmaceutical Scotognella, T.; Maccora, D.; Bruno, I.; Chinol, M.; Castagnola, M.; Collamati, F.; Mancini-Terraciano, C.; Morganti, S.; Bocci, V.; Solfaroli-Camillocci, E.; Rotili, D; Cartoni, A; Fratoddi, I; Marini, F.; Venditti, I.; Faccini, R.; Giordano, A. - 01a Articolo in rivista
rivista: CURRENT RADIOPHARMACEUTICALS (Bentham Science Publishers Ltd) pp. 32-39 - issn: 1874-4710 - wos: WOS:000808516000004 (2) - scopus: 2-s2.0-85127163927 (2)
11573/1622835 - 2022 -
The Nitrobenzoxadiazole Derivative NBDHEX Behaves as Plasmodium falciparum Gametocyte Selective Inhibitor with Malaria Parasite Transmission Blocking Activity Siciliano, G.; Di Paolo, V.; Rotili, D.; Migale, R.; Pedini, F.; Casella, M.; Camerini, S.; Dalzoppo, D.; Henderson, R.; Huijs, T.; Dechering, K. J.; Mai, A.; Caccuri, A. M.; Lalle, M.; Quintieri, L.; Alano, P. - 01a Articolo in rivista
rivista: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. 168- - issn: 1424-8247 - wos: WOS:000825152000002 (4) - scopus: 2-s2.0-85123900571 (4)
11573/1628559 - 2022 -
Biochemical functions and clinical characterizations of the sirtuins in diabetes-induced retinal pathologies Taurone, Samanta; De Ponte, Chiara; Rotili, Dante; De Santis, Elena; Mai, Antonello; Fiorentino, Francesco; Scarpa, Susanna; Artico, Marco; Micera, Alessandra - 01g Articolo di rassegna (Review)
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000782009200001 (12) - scopus: 2-s2.0-85127570606 (12)
11573/1617428 - 2022 -
Hydrophilic gold nanoparticles as Anti-PD-L1 antibody carriers. Synthesis and interface properties Venditti, I.; Cartoni, A.; Cerra, S.; Fioravanti, R.; Salamone, T. A.; Sciubba, F.; Tabocchini, M. A.; Dini, V.; Battocchio, C.; Iucci, G.; Carlini, L.; Faccini, R.; Collamati, F.; Mancini T, C.; Solfaroli C, E.; Morganti, S.; Giordano, A.; Scotognella, T.; Maccora, D.; Rotili, D.; Marchese, C.; Anastasiadou, E.; Trivedi, P.; Fratoddi, I. - 01a Articolo in rivista
rivista: PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 1-12 - issn: 0934-0866 - wos: WOS:000753440400001 (9) - scopus: 2-s2.0-85124617698 (10)
11573/1503800 - 2021 -
Regulatory interplay between mir-181a-5p and estrogen receptor signaling cascade in breast cancer Benedetti, R.; Papulino, C.; Sgueglia, G.; Chianese, U.; De Marchi, T.; Iovino, F.; Rotili, D.; Mai, A.; Nimeus, E.; Aversana, C. D.; Altucci, L. - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. 1-19 - issn: 2072-6694 - wos: WOS:000614992800001 (9) - scopus: 2-s2.0-85100578967 (11)
Fiorentino, F.; Carafa, V.; Favale, G.; Altucci, L.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
rivista: CANCERS (Basel: MDPI) pp. 1-26 - issn: 2072-6694 - wos: WOS:000627939700001 (33) - scopus: 2-s2.0-85102076188 (35)
11573/1585511 - 2021 -
Emerging Therapeutic Potential of SIRT6 Modulators Fiorentino, F.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9732-9758 - issn: 0022-2623 - wos: WOS:000677581000007 (38) - scopus: 2-s2.0-85110981411 (37)
11573/1585447 - 2021 -
Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein-protein interactions Fiorentino, F.; Rotili, D.; Mai, A.; Bolla, J. R.; Robinson, C. V. - 01a Articolo in rivista
rivista: CHEMICAL COMMUNICATIONS (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 10747-10750 - issn: 1359-7345 - wos: WOS:000700904000001 (8) - scopus: 2-s2.0-85117218452 (9)
11573/1585389 - 2021 -
Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives Fiorentino, Francesco; De Angelis, Marta; Menna, Martina; Rovere, Annarita; Maria Caccuri, Anna; D'acunzo, Francesca; Palamara, Anna Teresa; Nencioni, Lucia; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 2128-2138 - issn: 1475-6366 - wos: WOS:000700847900001 (5) - scopus: 2-s2.0-85116047224 (5)
11573/1611281 - 2021 -
Metabolic rewiring by loss of sirt5 promotes kras-induced pancreatic cancer progression Hu, T.; Shukla, S. K.; Vernucci, E.; He, C.; Wang, D.; King, R. J.; Jha, K.; Siddhanta, K.; Mullen, N. J.; Attri, K. S.; Murthy, D.; Chaika, N. V.; Thakur, R.; Mulder, S. E.; Pacheco, C. G.; Fu, X.; High, R. R.; Yu, F.; Lazenby, A.; Steegborn, C.; Lan, P.; Mehla, K.; Rotili, D.; Chaudhary, S.; Valente, S.; Tafani, M.; Mai, A.; Auwerx, J.; Verdin, E.; Tuveson, D.; Singh, P. K. - 01a Articolo in rivista
rivista: GASTROENTEROLOGY (USA: Elsevier
Philadelphia, PA: W B Saunders Company) pp. 1584-1600 - issn: 0016-5085 - wos: WOS:000711484200002 (52) - scopus: 2-s2.0-85115084196 (53)
11573/1576703 - 2021 -
Sirt5 inhibition induces brown fat-like phenotype in 3t3-l1 preadipocytes Molinari, Francesca; Feraco, Alessandra; Mirabilii, Simone; Saladini, Serena; Sansone, Luigi; Vernucci, Enza; Tomaselli, Giada; Marzolla, Vincenzo; Rotili, Dante; A Russo, Matteo; Ricciardi, Maria Rosaria; Tafuri, Agostino; Mai, Antonello; Caprio, Massimiliano; Tafani, Marco; Armani, Andrea - 01a Articolo in rivista
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 1-17 - issn: 2073-4409 - wos: WOS:000654660100001 (14) - scopus: 2-s2.0-85107437198 (18)
11573/1601697 - 2021 -
First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53 Nowak, R. P.; Tumber, A.; Hendrix, E.; Ansari, M. S. Z.; Sabatino, M.; Antonini, L.; Andrijes, R.; Salah, E.; Mautone, N.; Pellegrini, F. R.; Simelis, K.; Kawamura, A.; Johansson, C.; Passeri, D.; Pellicciari, R.; Ciogli, A.; Del Bufalo, D.; Ragno, R.; Coleman, M. L.; Trisciuoglio, D.; Mai, A.; Oppermann, U.; Schofield, C. J.; Rotili, D. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 17031-17050 - issn: 0022-2623 - wos: WOS:000754727400006 (8) - scopus: 2-s2.0-85120646873 (9)
11573/1601812 - 2021 -
JQ1, inibitore delle proteine BET, riduce i fattori di virulenza e la patogenicità di
Aspergillus fumigatus. Orekhova, A.; De Angelis, M.; Protto, V.; Rotili, D.; Mai, A.; A. T., Palamara.; Simonetti, G - 04d Abstract in atti di convegno
congresso: Nome convegno (Napoli)
libro: 13° Congresso Nazionale della Società Italiana di Microbiologia Farmaceutica Obiettivi e Sfide della Microbiologia Moderna per la Difesa della Salute - ()
11573/1408683 - 2020 -
The pan-sirtuin inhibitor MC2494 regulates mitochondrial function in a leukemia cell line Carafa, Vincenzo; Russo, Rosita; Della Torre, Laura; Cuomo, Francesca; Dell'aversana, Carmela; Sarno, Federica; Sgueglia, Giulia; Di Donato, Marzia; Rotili, Dante; Mai, Antonello; Nebbioso, Angela; Cobellis, Gilda; Chambery, Angela; Altucci, Lucia - 01a Articolo in rivista
rivista: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. - - issn: 2234-943X - wos: WOS:000539644000001 (8) - scopus: 2-s2.0-85085984851 (8)
11573/1434640 - 2020 -
CDK9 as a valuable target in cancer: from natural compounds inhibitors to current treatment in pediatric soft tissue sarcomas Cassandri, Matteo; Fioravanti, Rossella; Pomella, Silvia; Valente, Sergio; Rotili, Dante; Del Baldo, Giada; De Angelis, Biagio; Rota, Rossella; Mai, Antonello - 01a Articolo in rivista
rivista: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000565986100001 (19) - scopus: 2-s2.0-85089884656 (24)
11573/1387842 - 2020 -
Radioguided surgery with β− radiation in pancreatic Neuroendocrine tumors: a feasibility study Collamati, F.; Maccora, D.; Alfieri, S.; Bocci, V; Cartoni, A.; Collarino, A.; De Simoni, M.; Fischetti, M.; Fratoddi, I.; Giordano, A.; Mancini-Terracciano, C.; Mirabelli, R.; Morganti, S.; Quero, G.; Rotili, D.; Scotognella, T.; Solfaroli Camillocci, E.; Traini, G.; Venditti, I.; Faccini, R. - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature
London: Nature Publishing Group) pp. 1-10 - issn: 2045-2322 - wos: WOS:000563275200010 (6) - scopus: 2-s2.0-85080868854 (7)
11573/1429750 - 2020 -
Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni Coutinho Carneiro, V.; De Abreu Da Silva, I. C.; Amaral, M. S.; Pereira, A. S. A.; Silveira, G. O.; Pires, D. D. S.; Verjovski-Almeida, S.; Dekker, F. J.; Rotili, D.; Mai, A.; Lopes-Torres, E. J.; Robaa, D.; Sippl, W.; Pierce, R. J.; Borrello, M. T.; Ganesan, A.; Lancelot, J.; Thiengo, S.; Fernandez, M. A.; Vicentino, A. R. R.; Mourao, M. M.; Coelho, F. S.; Fantappie, M. R. - 01a Articolo in rivista
rivista: PLOS NEGLECTED TROPICAL DISEASES (San Francisco, CA : Public Library of Science) pp. - - issn: 1935-2735 - wos: WOS:000547527200003 (6) - scopus: 2-s2.0-85087471659 (7)
11573/1429748 - 2020 -
Characterization of water-soluble esters of nitrobenzoxadiazole-based GSTP1-1 inhibitors for cancer treatment Di Paolo, V.; Fulci, C.; Rotili, D.; De Luca, A.; Tomassi, S.; Serra, M.; Scimeca, M.; Geroni, C.; Quintieri, L.; Caccuri, A. M. - 01a Articolo in rivista
rivista: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited
-London ; New York : Pergamon Press, 1958-) pp. 114060- - issn: 0006-2952 - wos: WOS:000551658300022 (6) - scopus: 2-s2.0-85086125526 (6)
11573/1382315 - 2020 -
Tranylcypromine-based LSD1 inhibitors: structure-activity relationships, antiproliferative effects in leukemia, and gene target modulation Fioravanti, R.; Romanelli, A.; Mautone, N.; Di Bello, E.; Rovere, A.; Corinti, D.; Zwergel, C.; Valente, S.; Rotili, D.; Botrugno, O. A.; Dessanti, P.; Vultaggio, S.; Vianello, P.; Cappa, A.; Binda, C.; Mattevi, A.; Minucci, S.; Mercurio, C.; Varasi, M.; Mai, A. - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 643-658 - issn: 1860-7179 - wos: WOS:000513271600001 (19) - scopus: 2-s2.0-85079446800 (21)
11573/1425034 - 2020 -
Targeting histone acetylation/deacetylation in parasites: an update (2017–2020) Fioravanti, Rossella; Mautone, Nicola; Rovere, Annarita; Rotili, Dante; Mai, Antonello - 01g Articolo di rassegna (Review)
rivista: CURRENT OPINION IN CHEMICAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 65-74 - issn: 1367-5931 - wos: WOS:000568781700011 (38) - scopus: 2-s2.0-85086940284 (37)
11573/1585515 - 2020 -
Lysine Acetyltransferase Inhibitors From Natural Sources Fiorentino, F.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
rivista: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. 1243- - issn: 1663-9812 - wos: WOS:000565346900001 (21) - scopus: 2-s2.0-85089907540 (23)
Fiorentino, Francesco; Mai, Antonello; Rotili, Dante - 02a Capitolo o Articolo
libro: Histone Modifications in Therapy - (9780128164228)
11573/1401342 - 2020 -
Identification of Inhibitors to trypanosoma cruzi sirtuins based on compounds developed to human enzymes Matutino Bastos, Tanira; Botelho Pereira Soares, Milena; Haddad Franco, Caio; Alcântara, Laura; Antonini, Lorenzo; Sabatino, Manuela; Mautone, Nicola; Holanda Freitas-Junior, Lucio; Moraes, Carolina Borsoi; Ragno, Rino; Rotili, Dante; Schenkman, Sergio; Mai, Antonello; Silvio Moretti, Nilmar - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000539312100255 (9) - scopus: 2-s2.0-85085293622 (9)
11573/1384850 - 2020 -
Sirtuin modulators: where are we now? A review of patents from 2015 to 2019 Mautone, Nicola; Zwergel, Clemens; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
rivista: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare
-London, United Kingdom: Ashley Publications Limited) pp. - - issn: 1354-3776 - wos: WOS:000526337100001 (40) - scopus: 2-s2.0-85083571564 (40)
11573/1480930 - 2020 -
Recent advances in epigenetic proteolysis targeting chimeras (Epi-PROTACs) Tomaselli, D.; Mautone, N.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000591227400031 (14) - scopus: 2-s2.0-85089918812 (14)
11573/1408685 - 2020 -
Sirt4: a multifaceted enzyme at the crossroads of mitochondrial metabolism and cancer Tomaselli, D.; Steegborn, C.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
rivista: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. - - issn: 2234-943X - wos: WOS:000531334700001 (46) - scopus: 2-s2.0-85083986337 (48)
11573/1389775 - 2020 -
From PARP1 to TNKS2 inhibition: A structure-based approach Tomassi, Stefano; Pfahler, Julian; Mautone, Nicola; Rovere, Annarita; Esposito, Chiara; Passeri, Daniela; Pellicciari, Roberto; Novellino, Ettore; Pannek, Martin; Steegborn, Clemens; Paiardini, Alessandro; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
rivista: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. - - issn: 1948-5875 - wos: WOS:000535281200039 (8) - scopus: 2-s2.0-85087107488 (8)
11573/1355613 - 2019 -
H19-dependent transcriptional regulation of β3 and β4 integrins upon estrogen and hypoxia favors metastatic potential in prostate cancer Bacci, L.; Aiello, A.; Ripoli, C.; Loria, R.; Pugliese, D.; Pierconti, F.; Rotili, D.; Strigari, L.; Pinto, F.; Bassi, P. F.; Mai, A.; Grassi, C.; Pontecorvi, A.; Falcioni, R.; Farsetti, A.; Nanni, S. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000484411100169 (22) - scopus: 2-s2.0-85071378179 (21)
11573/1355598 - 2019 -
Inhibition of histone demethylases LSD1 and UTX regulates ERα signaling in breast cancer Benedetti, R.; Dell'aversana, C.; De Marchi, T.; Rotili, D.; Liu, N. Q.; Novakovic, B.; Boccella, S.; Di Maro, S.; Cosconati, S.; Baldi, A.; Nimeus, E.; Schultz, J.; Hoglund, U.; Maione, S.; Papulino, C.; Chianese, U.; Iovino, F.; Federico, A.; Mai, A.; Stunnenberg, H. G.; Nebbioso, A.; Altucci, L. - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000507382100204 (33) - scopus: 2-s2.0-85077269849 (36)
11573/1193778 - 2019 -
Identification of novel quinazoline derivatives as potent antiplasmodial agents Bouchut, A; Rotili, D; Pierrot, C; Valente, S; Lafitte, S; Schultz, J; Hoglund, U; Mazzone, R; Lucidi, A; Fabrizi, G; Pechalrieu, D; Arimondo, Pb; Skinner-Adams, Ts; Chua, Mj; Andrews, Kt; Mai, A; Khalife, J. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 277-291 - issn: 0223-5234 - wos: WOS:000451498200018 (45) - scopus: 2-s2.0-85055197167 (48)
11573/1336693 - 2019 -
Enzymatic and biological characterization of novel sirtuin modulators against cancer Carafa, V.; Poziello, A.; Torre, L. D.; Giovannelli, P.; Di Donato, M.; Safadeh, E.; Yu, Z.; Baldi, A.; Castoria, G.; Tomaselli, D.; Mai, A.; Rotili, D.; Nebbioso, A.; Altucci, L. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000502786800136 (9) - scopus: 2-s2.0-85074828780 (11)
11573/1355615 - 2019 -
Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis Di Paolo, V.; Fulci, C.; Rotili, D.; Sciarretta, F.; Lucidi, A.; Morozzo Della Rocca, B.; De Luca, A.; Rosato, A.; Quintieri, L.; Caccuri, A. M. - 01a Articolo in rivista
rivista: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 1131-1139 - issn: 1475-6366 - wos: WOS:000476871200001 (7) - scopus: 2-s2.0-85067475804 (8)
11573/1336760 - 2019 -
DNA Methylation: Biological Implications and Modulation of Its Aberrant Dysregulation Lucidi, Alessia; Tomaselli, Daniela; Rotili, Dante; Mai, Antonello - 02a Capitolo o Articolo
libro: The DNA, RNA, and Histone Methylomes - (978-3-030-14791-4; 978-3-030-14792-1)
11573/1306441 - 2019 -
Gold nanoparticles and nanorods in nuclear medicine: a mini review Maccora, Daria; Dini, Valentina; Battocchio, Chiara; Fratoddi, Ilaria; Cartoni, Antonella; Rotili, Dante; Castagnola, Massimo; Faccini, Riccardo; Bruno, Isabella; Scotognella, Teresa; Giordano, Alessandro; Venditti, Iole - 01g Articolo di rassegna (Review)
rivista: APPLIED SCIENCES (Basel: MDPI AG, 2011-) pp. - - issn: 2076-3417 - wos: WOS:000484444100026 (44) - scopus: 2-s2.0-85071043073 (49)
11573/1336715 - 2019 -
Structure-reactivity relationships on substrates and inhibitors of the lysine deacylase sirtuin 2 from schistosoma mansoni (SmSirt2) Monaldi, Daria; Rotili, Dante; Julien Lancelot, ‡; Martin Marek, §; Nathalie Wössner, ∥; Lucidi, Alessia; Tomaselli, Daniela; Elizabeth Ramos-Morales, ‡; Christophe Romier, ∥; Pierce, ∥ Raymond J.; Mai, Antonello; And Manfred Jung, ‡ - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8733-8759 - issn: 0022-2623 - wos: WOS:000490355000005 (19) - scopus: 2-s2.0-85072924967 (17)
11573/1221842 - 2019 -
Effect of α-methoxy substitution on the anti-HIV activity of dihydropyrimidin-4(3 H)-ones Nawrozkij, Maxim B.; Forgione, Mariantonietta; Yablokov, Alexandre S.; Lucidi, Alessia; Tomaselli, Daniela; Patsilinakos, Alexandros; Panella, Cristina; Hailu, Gebremedhin S.; Kirillov, Ivan A.; Badia, Roger; Riveira-Munoz, Eva; Crespan, Emmanuele; Armijos Rivera, Jorge I.; Cirilli, Roberto; Ragno, Rino; Esté, José A.; Maga, Giovanni; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 604-621 - issn: 0022-2623 - wos: WOS:000457067600015 (14) - scopus: 2-s2.0-85059424455 (12)
11573/1336742 - 2019 -
α,γ-Diketocarboxylic acids and their esters act as carbonic anhydrase IX and XII selective inhibitors Nocentini, Alessio; Lucidi, Alessia; Perut, Francesca; Massa, Annamaria; Tomaselli, Daniela; Gratteri, Paola; Baldini, Nicola; Rotili, Dante; Mai, Antonello; Supuran, Claudiu T. - 01a Articolo in rivista
rivista: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 661-665 - issn: 1948-5875 - wos: WOS:000464767700047 (18) - scopus: 2-s2.0-85064255109 (19)
11573/1339733 - 2019 -
Epigenetic modulators as a new strategies to reduce Aspergillus pathogenicity Orekhova, Anastasia; D’Auria, F. D.; Rotili, D.; Mai, A.; Palamara, A. T.; Simonetti, G - 04f Poster
congresso: 47° Congresso Nazionale della Società Italiana di Microbiologia (Roma)
libro: 47° Congresso Nazionale della Società Italiana di Microbiologia - ()
11573/1355611 - 2019 -
Effects of glutathione transferase-targeting nitrobenzoxadiazole compounds in relation to PD-L1 status in human melanoma cells Sciarretta, F.; Fulci, C.; Palumbo, C.; Rotili, D.; Tentori, L.; Graziani, G.; Caccuri, A. M. - 01a Articolo in rivista
rivista: CHEMOTHERAPY (S Karger AG:Allschwilerstrasse 10, CH-4009 Basel Switzerland:011 41 61 3061111, EMAIL: orders@karger.ch, INTERNET: http://www.karger.com, Fax: 011 41 61 3061234) pp. 138-145 - issn: 0009-3157 - wos: WOS:000501814700004 (5) - scopus: 2-s2.0-85074343924 (5)
11573/1355609 - 2019 -
Comparison of the effects of synthetic and plant-derived mTOR regulators on healthy human ovarian cells Sirotkin, A. V.; Adamcova, E.; Rotili, D.; Mai, A.; Mlyncek, M.; Mansour, L.; Alwasel, S.; Harrath, A. H. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF PHARMACOLOGY (AMSTERDAM, NETHERLANDS: ELSEVIER SCIENCE) pp. 70-78 - issn: 0014-2999 - wos: WOS:000468305200009 (1) - scopus: 2-s2.0-85063965408 (2)
11573/1336730 - 2019 -
Epigenetic polypharmacology: a new frontier for epi-drug discovery Tomaselli, Daniela; Lucidi, Alessia; Rotili, Dante; Mai, Antonello - 01g Articolo di rassegna (Review)
rivista: MEDICINAL RESEARCH REVIEWS ([New York, N.Y.] : Wiley) pp. 190-244 - issn: 1098-1128 - wos: WOS:000534635500009 (69) - scopus: 2-s2.0-85075138650 (80)
11573/1355619 - 2019 -
Histone Acetyltransferase Enzymes: From Biological Implications to Most Relevant Inhibitors Trisciuoglio, Daniela; Rotili, Dante - 02a Capitolo o Articolo
libro: Topics in medicinal chemistry - ()
11573/1355602 - 2019 -
Histone deacetylase inhibitors exert anti-tumor effects on human adherent and stem-like glioma cells 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis Was, H.; Krol, S. K.; Rotili, D.; Mai, A.; Wojtas, B.; Kaminska, B.; Maleszewska, M. - 01a Articolo in rivista
rivista: CLINICAL EPIGENETICS (Berlin : Springer) pp. 11- - issn: 1868-7083 - wos: WOS:000456005400002 (53) - scopus: 2-s2.0-85060173887 (51)
Zwergel, Clemens; Rotili, Dante; Valente, Sergio; Mai, Antonello - 02a Capitolo o Articolo
libro: Epigenetic Drug Discovery - (9783527343140; 9783527809257)
11573/1116555 - 2018 -
RIP1-HAT1-SirT complex identification and targeting in treatment and prevention of cancer Carafa, Vincenzo; Nebbioso, Angela; Cuomo, Francesca; Rotili, Dante; Cobellis, Gilda; Bontempo, Paola; Baldi, Alfonso; Spugnini, Enrico P.; Citro, Alfonso Gennaro; Chambery, Angela; Russo, Rosita; Ciana, Paolo; Maravigna, Luca; Shaik, Jani; Radaelli, Enrico; De Antonellis, Pasquale; Tarantino, Domenico; Pirolli, Adele; Ragno, Rino; Massimo Zollo, .; Stunnenberg, Hendrik G.; Mai, Antonello; Altucci, Lucia - 01a Articolo in rivista
rivista: CLINICAL CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 2886-2900 - issn: 1078-0432 - wos: WOS:000435462700019 (34) - scopus: 2-s2.0-85052287980 (36)
11573/1115449 - 2018 -
KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2 Cocco, Elisa; Leo, Manuela; Canzonetta, Claudia; Di Vito, Serena; Mai, Antonello; Rotili, Dante; Di Napoli, Arianna; Vecchione, Andrea; De Nunzio, Cosimo; Filetici, Patrizia; Stoppacciaro, Antonella - 01a Articolo in rivista
rivista: CLINICAL EPIGENETICS (Berlin : Springer) pp. 1-16 - issn: 1868-7083 - wos: WOS:000429840100001 (10) - scopus: 2-s2.0-85045003305 (12)
11573/1147231 - 2018 -
Lysine acetyltransferase inhibitors: structure-activity relationships and potential therapeutic implications Fiorentino, Francesco; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
rivista: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 1067-1091 - issn: 1756-8919 - wos: WOS:000431874300008 (24) - scopus: 2-s2.0-85046873546 (23)
11573/1174039 - 2018 -
Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells Iachettini, Sara; Trisciuoglio, Daniela; Rotili, Dante; Lucidi, Alessia; Salvati, Erica; Zizza, Pasquale; Di Leo, Luca; Del Bufalo, Donatella; Rosa Ciriolo, Maria; Leonetti, Carlo; Steegborn, Clemens; Mai, Antonello; Rizzo, Angela; Annamaria Biroccio, And - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. 996- - issn: 2041-4889 - wos: WOS:000446267200026 (64) - scopus: 2-s2.0-85053859793 (72)
11573/1118719 - 2018 -
Mass spectrometry characterization of DOTA-Nimotuzumab conjugate as precursor of an innovative β − tracer suitable in radio-guided surgery Martelli, C.; Marzano, V.; Marini, F.; Scotognella, T.; Fratoddi, I.; Venditti, I; Rotili, D.; Solfaroli C., E.; Collamati, F.; Mancini T., C.; Morganti, S.; Maccora, D.; Faccini, R.; Cartoni, A; Giordano, A.; Castagnola, M. - 01a Articolo in rivista
rivista: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (Oxford ; New York : Pergamon Press
Amsterdam : Elsevier Science) pp. 8-15 - issn: 0731-7085 - wos: WOS:000435228400002 (5) - scopus: 2-s2.0-85046479862 (6)
11573/1065694 - 2018 -
Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches Sabatino, Manuela; Rotili, Dante; Patsilinakos, Alexandros; Forgione, Mariantonietta; Tomaselli, Daniela; Alby, Fréderic; Arimondo, Paola B.; Mai, Antonello; Ragno, Rino - 01a Articolo in rivista
rivista: JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (-SPRINGER, VAN GODEWIJCKSTRAAT 30, DORDRECHT, NETHERLANDS, 3311 GZ
-Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: frontoffice@wkap.nl, kluweronline@wkap.nl, INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254) pp. 435-458 - issn: 0920-654X - wos: WOS:000425293300003 (16) - scopus: 2-s2.0-85041359880 (15)
11573/1602341 - 2017 -
Corrigendum: Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma Coni, S.; Mancuso, A. B.; Di Magno, L.; Sdruscia, G.; Manni, S.; Serrao, S. M.; Rotili, D.; Spiombi, E.; Bufalieri, F.; Petroni, M.; Kusio-Kobialka, M.; De Smaele, E.; Ferretti, E.; Capalbo, C.; Mai, A.; Niewiadomski, P.; Screpanti, I.; Di Marcotullio, L.; Canettieri, G. - 01b Commento, Erratum, Replica e simili
rivista: SCIENTIFIC REPORTS (London: Springer Nature
London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000399974300001 (5) - scopus: 2-s2.0-85068766477 (4)
11573/946157 - 2017 -
Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma. Coni, Sonia; Mancuso, Anna Barbara; Di Magno, L; Sdruscia, Giulia; Manni, Simona; Serrao, Silvia Maria; Rotili, Dante; Spiombi, Eleonora; Bufalieri, Francesca; Petroni, Marialaura; Kusio Kobialka, M; De Smaele, Enrico; Ferretti, Elisabetta; Capalbo, Carlo; Mai, Antonello; Niewiadomski, P; Screpanti, Isabella; Di Marcotullio, Lucia; Canettieri, Gianluca - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature
London: Nature Publishing Group) pp. 44079- - issn: 2045-2322 - wos: WOS:000396136700001 (54) - scopus: 2-s2.0-85014895304 (54)
11573/944093 - 2017 -
The nitrobenzoxadiazole derivative MC3181 blocks melanoma invasion and metastasis. De Luca, A; Carpanese, D; Rapanotti, Mc; Viguria, Tm; Forgione, Ma; Rotili, Dante; Fulci, C; Iorio, E; Quintieri, L; Chimenti, S; Bianchi, L; Rosato, A; Caccuri, A. M. 1. - 01a Articolo in rivista
rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 15520-15538 - issn: 1949-2553 - wos: WOS:000396013700106 (17) - scopus: 2-s2.0-85014078650 (17)
11573/944092 - 2017 -
A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability. Fulci, C; Rotili, Dante; De Luca, A; Stella, L; Morozzo Della Rocca, B; Forgione, M; Di Paolo, V; Mai, Antonello; Falconi, M; Quintieri, L; Caccuri, Am; 7, . - 01a Articolo in rivista
rivista: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 240-247 - issn: 1475-6366 - wos: WOS:000392591100017 (18) - scopus: 2-s2.0-85015590345 (18)
11573/1027812 - 2017 -
Lysine deacetylase inhibitors in parasites: past, present, and future perspectives. Hailu, Gs; Robaa, D; Forgione, M; Sippl, W; Rotili, D; Mai, A. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4780-4804 - issn: 0022-2623 - wos: WOS:000404202200002 (67) - scopus: 2-s2.0-85021131721 (71)
11573/1027154 - 2017 -
Feasibility of beta-particle radioguided surgery for a variety of “nuclear medicine” radionuclides Mancini Terracciano, C; Donnarumma, R; Bencivenga, G.; Bocci, V.; Cartoni, A.; Collamati, F.; Fratoddi, I.; Giordano, A.; Indovina, L.; Maccora, D.; Marafini, M.; Mirabelli, R.; Morganti, S.; Rotili, D.; Russomando, A.; Scotognella, T.; Solfaroli C, E.; Toppi, M; Traini, G.; Venditti, I.; Faccini, R. - 01a Articolo in rivista
rivista: PHYSICA MEDICA (UK: Elsevier
Pisa: Istituti Editoriali e Poligrafici Internazionali.
Pisa Italy: Giardini Editori Stampatori) pp. 127-133 - issn: 1120-1797 - wos: WOS:000417655800016 (22) - scopus: 2-s2.0-85036555361 (25)
11573/947675 - 2017 -
Development of 1,2,4-oxadiazoles as potent and selective inhibitors of the human deacetylase sirtuin 2: structure-activity relationship, X-ray crystal structure, and anticancer activity Moniot, S; Forgione, M; Lucidi, Alessia; Hailu, Gebremedhin Solomon; Nebbioso, A; Carafa, V; Baratta, F; Altucci, L; Giacché, N; Passeri, D; Pellicciari, R; Mai, Antonello; Steegborn, C; Rotili, Dante - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2344-2360 - issn: 0022-2623 - wos: WOS:000397546000013 (77) - scopus: 2-s2.0-85016147565 (80)
11573/944090 - 2017 -
Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity. Ourailidou, Me; Lenoci, A; Zwergel, Clemens; Rotili, Dante; Mai, Antonello; Dekker, F. J. 4. - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 847-856 - issn: 0968-0896 - wos: WOS:000394201900004 (9) - scopus: 2-s2.0-85008433321 (10)
11573/1027813 - 2017 -
Crystal structures of the mitochondrial deacylase Sirtuin 4 reveal isoform-specific acyl recognition and regulation features. Pannek, M; Simic, Z; Fuszard, M; Meleshin, M; Rotili, D; Mai, A; Schutkowski, M; Steegborn, C. - 01a Articolo in rivista
rivista: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. - - issn: 2041-1723 - wos: WOS:000415262500001 (70) - scopus: 2-s2.0-85034035870 (73)
11573/1017768 - 2017 -
Y3+ embedded in polymeric nanoparticles: Morphology, dimension and stability of composite colloidal system Venditti, I; Cartoni, A.; Fontana, L.; Testa, G.; Scaramuzzo, F. A.; Faccini, R.; Mancini Terracciano, C.; Solfaroli Camillocci, E.; Morganti, S.; Giordano, A.; Scotognella, T.; Rotili, D.; Dini, V.; Marini, F.; Fratoddi, I - 01a Articolo in rivista
rivista: COLLOIDS AND SURFACES. A, PHYSICOCHEMICAL AND ENGINEERING ASPECTS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 125-131 - issn: 0927-7757 - wos: WOS:000412065600018 (20) - scopus: 2-s2.0-85020137711 (20)
11573/1027810 - 2017 -
The relevance of Ki calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor. Wapenaar, H; Van Den Bosch, T; Leus, Ngj; Van Der Wouden, Pe; Eleftheriadis, N; Hermans, J; Hailu, Gs; Rotili, D; Mai, A; Dömling, A; Bischoff, R; Haisma, Hj; Dekker, F. J. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 480-486 - issn: 0223-5234 - wos: WOS:000403993500041 (5) - scopus: 2-s2.0-85019413230 (6)
11573/944091 - 2017 -
Structural basis of sirtuin 6 activation by synthetic small molecules. You, W; Rotili, Dante; Li, Tm; Kambach, C; Meleshin, M; Schutkowski, M; Chua, Kf; Mai, Antonello; Steegborn, C. 1. - 01a Articolo in rivista
rivista: ANGEWANDTE CHEMIE. INTERNATIONAL EDITION (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 1007-1011 - issn: 1433-7851 - wos: WOS:000394997200011 (114) - scopus: 2-s2.0-85006998900 (122)
11573/884147 - 2016 -
Sirtuin functions and modulation: from chemistry to the clinic Carafa, Vincenzo; Rotili, Dante; Forgione, Mariantonietta; Cuomo, Francesca; Serretiello, Enrica; Hailu, Gebremedhin Solomon; Jarho, Elina; Lahtela Kakkonen, Maija; Mai, Antonello; Altucci, Lucia - 01a Articolo in rivista
rivista: CLINICAL EPIGENETICS (Berlin : Springer) pp. 1-21 - issn: 1868-7083 - wos: WOS:000376856700001 (263) - scopus: 2-s2.0-84973864104 (277)
11573/884154 - 2016 -
Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells Chano, Tokuhiro; Avnet, Sofia; Kusuzaki, Katsuyuki; Bonuccelli, Gloria; Sonveaux, Pierre; Rotili, Dante; Mai, Antonello; Baldini, Nicola - 01a Articolo in rivista
rivista: AMERICAN JOURNAL OF CANCER RESEARCH (Madison, WI: Published by e-Century Publishing Corporation, Madison) pp. 859-875 - issn: 2156-6976 - wos: WOS:000384444300002 (29) - scopus: 2-s2.0-84991518619 (31)
11573/884170 - 2016 -
Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells Di Martile, Marta; Desideri, Marianna; De Luca, Teresa; Gabellini, Chiara; Buglioni, Simonetta; Eramo, Adriana; Sette, Giovanni; Milella, Michele Stanislaw; Rotili, Dante; Mai, Antonello; Carradori, Simone; Secci, Daniela; De Maria, Ruggero; Del Bufalo, Donatella; Trisciuoglio, Daniela - 01a Articolo in rivista
rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 11332-11348 - issn: 1949-2553 - wos: WOS:000375678300047 (37) - scopus: 2-s2.0-84962019515 (38)
11573/871180 - 2016 -
c-Jun N-terminal kinase activation by nitrobenzoxadiazoles leads to late-stage autophagy inhibition Palumbo, Camilla; De Luca, Anastasia; Rosato, Nicola; Forgione, Mariantonietta; Rotili, Dante; Caccuri, Anna Maria - 01a Articolo in rivista
rivista: JOURNAL OF TRANSLATIONAL MEDICINE (London: BioMed Central, London) pp. - - issn: 1479-5876 - wos: WOS:000369219900001 (23) - scopus: 2-s2.0-84958170303 (23)
11573/894532 - 2016 -
At long last potent and selective KDM5 inhibitors Rotili, Dante; Mattevi, Andrea - 01a Articolo in rivista
rivista: CELL CHEMICAL BIOLOGY (Amsterdam : Elsevier
Cambridge, MA : Cell Press) pp. 749-751 - issn: 2451-9456 - wos: WOS:000381509200001 (4) - scopus: 2-s2.0-84984910817 (4)
11573/894534 - 2016 -
Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features Speranzini, Valentina; Rotili, Dante; Ciossani, Giuseppe; Pilotto, Simona; Marrocco, Biagina; Forgione, Mariantonietta; Lucidi, Alessia; Forneris, Federico; Mehdipour, Parinaz; Velankar, Sameer; Mai, Antonello; Mattevi, Andrea - 01a Articolo in rivista
rivista: SCIENCE ADVANCES (Washington, DC : American Association for the Advancement of Science, 2015-) pp. - - issn: 2375-2548 - wos: WOS:000383734400025 (59) - scopus: 2-s2.0-85020596495 (60)
11573/884171 - 2016 -
The histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases Van Den Bosch, Thea; Boichenko, Alexander; Leus, Niek G. J.; Ourailidou, Maria E.; Wapenaar, Hannah; Rotili, Dante; Mai, Antonello; Imhof, Axel; Bischoff, Rainer; Haisma, Hidde J.; Dekker, Frank J. - 01a Articolo in rivista
rivista: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited
-London ; New York : Pergamon Press, 1958-) pp. 130-140 - issn: 0006-2952 - wos: WOS:000371446300011 (39) - scopus: 2-s2.0-84958753301 (50)
11573/884205 - 2015 -
A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts De Luca, Anastasia; Rotili, Dante; Carpanese, Debora; Lenoci, Alessia; Calderan, Laura; Scimeca, Manuel; Mai, Antonello; Bonanno, Elena; Rosato, Antonio; Geroni, Cristina; Quintieri, Luigi; Caccuri, Anna Maria - 01a Articolo in rivista
rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 4126-4143 - issn: 1949-2553 - wos: WOS:000352696200052 (23) - scopus: 2-s2.0-84924251939 (26)
11573/784167 - 2015 -
Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells G., Di Pompo; M., Salerno; Rotili, Dante; Valente, Sergio; Zwergel, Clemens; S., Avnet; G., Lattanzi; N., Baldini; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4073-4079 - issn: 0022-2623 - wos: WOS:000354911200031 (53) - scopus: 2-s2.0-84929378676 (52)
11573/884194 - 2015 -
A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib Graziani, Grazia; Artuso, Simona; De Luca, Anastasia; Muzi, Alessia; Rotili, Dante; Scimeca, Manuel; Atzori, Maria Grazia; Ceci, Claudia; Mai, Antonello; Leonetti, Carlo; Levati, Lauretta; Bonanno, Elena; Tentori, Lucio; Caccuri, Anna Maria - 01a Articolo in rivista
rivista: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited
-London ; New York : Pergamon Press, 1958-) pp. 16-27 - issn: 0006-2952 - wos: WOS:000353858800002 (29) - scopus: 2-s2.0-84930886228 (29)
11573/789900 - 2015 -
SIRT5 regulation of ammonia-induced autophagy and mitophagy Polletta, Lucia; Vernucci, Enza; Carnevale, Ilaria; Arcangeli, Tania; Rotili, Dante; Palmerio, Silvia; Steegborn, Clemens; Nowak, Theresa; Schutkowski, Mike; Pellegrini, Laura; Sansone, Luigi; Villanova, Lidia; Runci, Alessandra; Pucci, Bruna; Morgante, Emanuela; Fini, Massimo; Mai, Antonello; Russo, Matteo A; Tafani, Marco - 01a Articolo in rivista
rivista: AUTOPHAGY (Landes Bioscience Georgetown TX 78628) pp. 253-270 - issn: 1554-8627 - wos: WOS:000352778700007 (209) - scopus: 2-s2.0-84943265499 (219)
11573/680651 - 2015 -
Synthesis and structure-activity relationship of new cytotoxic agents targeting human glutathione-S-transferases. Rotili, Dante; De Luca, A; Tarantino, D; Pezzola, S; Forgione, Mariantonietta; Morozzo Della Rocca, B; Falconi, M; Mai, Antonello; Caccuri, A. M. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 156-171 - issn: 0223-5234 - wos: WOS:000348003500017 (30) - scopus: 2-s2.0-84908450815 (33)
11573/779609 - 2015 -
Pyrrole- and indole-containing tranylcypromine derivatives as novel lysine-specific demethylase 1 inhibitors active on cancer cells. Veronica, Rodriguez; Valente, Sergio; Stefano, Rovida; Rotili, Dante; Stazi, Giulia; Lucidi, Alessia; Giuseppe, Ciossani; Andrea, Mattevi; Oronza A., Botrugno; Paola, Dessanti; Ciro, Mercurio; Paola, Vianello; Saverio, Minucci; Mario, Varasi; Mai, Antonello - 01a Articolo in rivista
rivista: MEDCHEMCOMM (Cambridge : Royal Society of Chemistry, 2010-) pp. 665-670 - issn: 2040-2503 - wos: WOS:000352903400023 (22) - scopus: 2-s2.0-84928004801 (23)
11573/884188 - 2015 -
Targeting lysine deacetylases (KDACs) in parasites Wang, Qi; Rosa, Bruce A.; Nare, Bakela; Powell, Kerrie; Valente, Sergio; Rotili, Dante; Mai, Antonello; Marshall, Garland R.; Mitreva, Makedonka - 01a Articolo in rivista
rivista: PLOS NEGLECTED TROPICAL DISEASES (San Francisco, CA : Public Library of Science) pp. e000426- - issn: 1935-2727 - wos: WOS:000363031200020 (38) - scopus: 2-s2.0-84943193825 (41)
11573/884182 - 2015 -
Enzyme kinetics and inhibition of histone acetyltransferase KAT8 Wapenaar, Hannah; Van Der Wouden, Petra E; Groves, Matthew R; Rotili, Dante; Mai, Antonello; Dekker, Frank J. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ([Paris] : Elsevier, [198?]-) pp. 289-296 - issn: 1768-3254 - wos: WOS:000364891400020 (26) - scopus: 2-s2.0-84945264596 (28)
11573/1155213 - 2014 -
Sirtuins blunt reactive gliosis in an in vitro model of Alzheimer’s disease. Bronzuoli, Maria Rosanna; Scuderi, Caterina; Stecca, Claudia; Rotili, Dante; Valente, Sergio; Cugno, Michele; Mai, Antonello; Steardo, Luca. - 04d Abstract in atti di convegno
congresso: 17° Simposio SIF Dottorandi, Assegnisti di Ricerca Postdottorandi e Specializzandi in Farmacologia e Scienze Affini (Rimini)
libro: 17° Simposio SIF Dottorandi, Assegnisti di Ricerca Postdottorandi e Specializzandi in Farmacologia e Scienze Affini. - ()
11573/685071 - 2014 -
Evaluation of a large library of (thiazol-2-yl)hydrazones and analogues as histone acetyltransferase inhibitors: Enzyme and cellular studies. Carradori, S; Rotili, Dante; De Monte, Celeste; Lenoci, A; D'ascenzio, M; Rodriguez, V; Filetici, Patrizia; Miceli, M; Nebbioso, A; Altucci, L; Secci, Daniela; Mai, Antonello - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 569-578 - issn: 0223-5234 - wos: WOS:000337985400049 (46) - scopus: 2-s2.0-84900559630 (53)
11573/556419 - 2014 -
Context-Selective Death of Acute Myeloid Leukemia Cells Triggered by the Novel Hybrid Retinoid-HDAC Inhibitor MC2392. De Bellis, F; Carafa, V; Conte, M; Rotili, Dante; Petraglia, F; Matarese, F; Françoijs, Kj; Ablain, J; Valente, Sergio; Castellano, R; Goubard, A; Collette, Y; Mandoli, A; Martens, Jh; De Thé, H; Nebbioso, A; Mai, Antonello; Stunnenberg, Hg; Altucci, L. - 01a Articolo in rivista
rivista: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 2328-2339 - issn: 0008-5472 - wos: WOS:000334584200020 (28) - scopus: 2-s2.0-84899541163 (33)
11573/556417 - 2014 -
Quinoline-based p300 histone acetyltransferase inhibitors with pro-apoptotic activity in human leukemia U937 cells. Lenoci, Alessia; Tomassi, S; Conte, M; Benedetti, R; Rodriguez, V; Carradori, Simone; Secci, Daniela; Castellano, S; Sbardella, G; Filetici, P; Novellino, E; Altucci, L; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 542-548 - issn: 1860-7187 - wos: WOS:000331795500010 (26) - scopus: 2-s2.0-84896698147 (27)
11573/542432 - 2014 -
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities Rotili, Dante; Stefano, Tomassi; Mariarosaria, Conte; Rosaria, Benedetti; Marcello, Tortorici; Giuseppe, Ciossani; Valente, Sergio; Marrocco, Biagina; Labella, Donatella; Ettore, Novellino; Andrea, Mattevi; Lucia, Altucci; Tumber, Anthony; Yapp, Clarence; N. F., King Oliver; Richard J., Hopkinson; Akane, Kawamura; J., Schofield Christopher; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 42-55 - issn: 0022-2623 - wos: WOS:000329677800004 (93) - scopus: 2-s2.0-84892565144 (102)
11573/681257 - 2014 -
Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity. Rotili, Dante; Tarantino, D; Marrocco, Biagina; Gros, C; Masson, V; Poughon, V; Ausseil, F; Chang, Y; Labella, D; Cosconati, S; Di Maro, S; Novellino, E; Schnekenburger, M; Grandjenette, C; Bouvy, C; Diederich, M; Cheng, X; Arimondo, Pb; Mai, Antonello - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. - - issn: 1932-6203 - wos: WOS:000338213300096 (31) - scopus: 2-s2.0-84901487126 (35)
11573/681252 - 2014 -
Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes Rotili, Dante; Tarantino, D; Nawrozkij, Mb; Babushkin, As; Botta, G; Marrocco, Biagina; Cirilli, R; Menta, Sergio; Badia, R; Crespan, E; Ballante, Flavio; Ragno, Rino; Esté, Ja; Maga, G; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5212-5225 - issn: 0022-2623 - wos: WOS:000338184100018 (18) - scopus: 2-s2.0-84903515653 (18)
11573/643824 - 2014 -
Sirtuin modulators control reactive gliosis in an in vitro model of alzheimer's disease Scuderi, Caterina; Stecca, Claudia; Bronzuoli, Maria Rosanna; Rotili, Dante; Valente, Sergio; Mai, Antonello; Steardo, Luca - 01a Articolo in rivista
rivista: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000347086800001 (51) - scopus: 2-s2.0-84904631078 (56)
11573/553541 - 2014 -
I kappa B kinase (IKK)-epsilon targets interferon regulatory factor 1 in activated T lymphocytes. Sgarbanti, M; Marsili, G; Remoli, Al; Stellacci, E; Mai, Antonello; Rotili, Dante; Perrotti, E; Acchioni, C; Orsatti, R; Iraci, N; Ferrari, M; Borsetti, A; Hiscott, J; Battistini, A. - 01a Articolo in rivista
rivista: MOLECULAR AND CELLULAR BIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 1054-1065 - issn: 0270-7306 - wos: WOS:000331995800012 (28) - scopus: 2-s2.0-84894284462 (30)
11573/513467 - 2013 -
Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue. Galmozzi, A.; Mitro, N.; Ferrari, A.; Gers, E.; Gilardi, F.; Godio, C.; Cermenati, G.; Gualerzi, A.; Donetti, E.; Rotili, Dante; Valente, Sergio; Guerrini, U.; Caruso, D.; Mai, Antonello; Saez, E.; De Fabiani, E.; Crestani, M. - 01a Articolo in rivista
rivista: DIABETES (American Diabetes Association:National Service Center, 1701 North Beaureguard Street:Alexandria, VA 22311:(800)232-3472, (703)549-1500, INTERNET: http://www.diabetes.org/diabetscare, Fax: (703)549-6995) pp. 732-742 - issn: 0012-1797 - wos: WOS:000315556400017 (178) - scopus: 2-s2.0-84869106554 (195)
11573/525206 - 2013 -
PARP-1 Modulates Amyloid Beta Peptide-Induced Neuronal Damage Martire, Sara; Fuso, Andrea; Rotili, Dante; Tempera, Italo; Giordano, Cesare Giovanni; Ivana De, Zottis; Alessia, Muzi; Patrizia, Vernole; Grazia, Graziani; Emanuela, Lococo; Faraldi, Martina; Maras, Bruno; Scarpa, Sigfrido; Mosca, Luciana; D'erme, Maria - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e72169- - issn: 1932-6203 - wos: WOS:000325025200005 (54) - scopus: 2-s2.0-84884573236 (65)
11573/525223 - 2013 -
ROLE OF POLY(ADP-RIBOSE)POLYMERASE IN AMYLOID BETA TOXICITY AND ALZHEIMER DISEASE Mosca, Luciana; Fuso, Andrea; Martire, Sara; Rotili, Dante; Giordano, Cesare Giovanni; Emanuela, Lococo; Faraldi, Martina; P., Vernole; G., Graziani; Francioso, Antonio; Maras, Bruno; M., D'erme - 04a Atto di comunicazione a congresso
congresso: AD/PD 2013 (Firenze)
libro: Abstract book - ()
11573/442878 - 2012 -
An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases Anup K., Upadhyay; Rotili, Dante; Ji Woong, Han; Ruogu, Hu; Yanqi, Chang; Donatella, Labella; Xing, Zhang; Young Sup, Yoon; Mai, Antonello; Xiaodong, Cheng - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD,
-London; New York: Academic Press.) pp. 319-327 - issn: 0022-2836 - wos: WOS:000301313600001 (44) - scopus: 2-s2.0-84862777760 (47)
11573/511464 - 2012 -
PARP-1 inhibition decreases Beta-Amyloid-induced neurodegeneration: a cellular and animal model study Martire, Sara; Fuso, Andrea; Rotili, Dante; A., Muzi; Giordano, Cesare Giovanni; P., Vernole; E., Lococo; Faraldi, Martina; Masci, Alessandra; Miele, Adriana Erica; G., Graziani; Scarpa, Sigfrido; Mosca, Luciana; D'erme, Maria - 04c Atto di convegno in rivista
rivista: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. S182- - issn: 0891-5849 - wos: WOS:000209480800378 (0) - scopus: (0)
congresso: 16th SFRRI Biennial Meeting (London)
11573/895421 - 2012 -
6-(Arylmethyl)pyrimidin-4(3H)-ones: Anthology and prospects of highly efficient anti-HIV agents Novakov, I. A.; Artico, M.; Mai, Antonello; Rotili, Dante; Orlinson, B. S.; Brunilina, L. L.; Nawrozkij, M. B. - 01a Articolo in rivista
rivista: RUSSIAN CHEMICAL BULLETIN (- New York : SPRINGER
-New York : Consultants Bureau, c1993-) pp. 1399-1418 - issn: 1066-5285 - wos: WOS:000321771700009 (11) - scopus: 2-s2.0-84887395127 (11)
11573/495328 - 2012 -
Carprofen Analogues as Sirtuin Inhibitors: Enzyme and Cellular Studies Paolo, Mellini; Vincenzo, Carafa; Barbara Di, Rienzo; Rotili, Dante; De Vita, Daniela; Roberto, Cirilli; Bruno, Gallinella; Donatella Paola, Provvisiero; Salvatore Di, Maro; Ettore, Novellino; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1905-1908 - issn: 1860-7187 - wos: WOS:000310485200005 (14) - scopus: 2-s2.0-84868149996 (15)
11573/455654 - 2012 -
2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies. Rotili, Dante; A., Samuele; Domenico, Tarantino; Ragno, Rino; Musmuca, Ira; Ballante, Flavio; G., Botta; Morera, Ludovica; Pierini, Marco; R., Cirilli; M. B., Nawrozkij; E., Gonzalez; B., Clotet; Marino, Artico; J. A., Este; G., Maga; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 3558-3562 - issn: 1520-4804 - wos: WOS:000302591100058 (29) - scopus: 2-s2.0-84859804994 (31)
11573/485200 - 2012 -
Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells. Rotili, Dante; Tarantino, D; Carafa, V; Paolini, C; Schemies, J; Jung, M; Botta, G; Di Maro, S; Novellino, E; Steinkühler, C; De Maria, R; Gallinari, P; Altucci, L; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8193-8197 - issn: 0022-2623 - wos: WOS:000309153500023 (28) - scopus: 2-s2.0-84866849116 (32)
11573/759461 - 2012 -
Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells. Rotili, Dante; Tarantino, D; Nebbioso, A; Paolini, C; Huidobro, C; Lara, E; Mellini, P; Lenoci, Alessia; Pezzi, R; Botta, G; Lahtela Kakkonen, M; Poso, A; Steinkühler, C; Gallinari, P; De Maria, R; Fraga, M; Esteller, M; Altucci, L; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 10937-10947 - issn: 0022-2623 - wos: WOS:000312681100009 (75) - scopus: 2-s2.0-84871662210 (78)
11573/485203 - 2012 -
p300/CBP-associated factor selectively regulates the extinction of conditioned fear. W., Wei; C. M., Coelho; X., Li; R., Marek; S., Yan; S., Anderson; D., Meyers; C., Mukherjee; G., Sbardella; S., Castellano; C., Milite; Rotili, Dante; Mai, Antonello; P. A., Cole; P., Sah; M. S., Kobor; T. W., Bredy - 01a Articolo in rivista
rivista: THE JOURNAL OF NEUROSCIENCE (Baltimore MD: Society of Neuroscience) pp. 11930-11941 - issn: 0270-6474 - wos: WOS:000308213900003 (69) - scopus: 2-s2.0-84865472870 (75)
11573/442881 - 2011 -
Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors Gianluca, Sbardella; Mai, Antonello; Sara, Bartolini; Sabrina, Castellano; Roberto, Cirilli; Rotili, Dante; Ciro, Milite; Marisabella, Santoriello; Serena, Orlando; Ilaria, Sciamanna; Annalucia, Serafino; Patrizia, Lavia; Corrado, Spadafora - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5927-5936 - issn: 0022-2623 - wos: WOS:000294077300023 (12) - scopus: 2-s2.0-80051873043 (14)
11573/442885 - 2011 -
Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3'-C-methyladenosine in leukaemia cells. Meli, M; Tolomeo, M; Grifantini, M; Mai, Antonello; Cappellacci, L; Petrelli, R; Rotili, Dante; Ferro, A; Saiko, P; Szekeres, T; Dusonchet, L. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF ONCOLOGY (National Hellenic Research Foundation:48 Vas Constatinou Avenue, Athens 11635 Greece:011 30 1 7241505, Fax: 011 30 1 7241505Editore attuale:PROFESSOR D A SPANDIDOS, 1, S MERKOURI ST, EDITORIAL OFFICE,, ATHENS, GREECE, 116 35.
Editore precedente:Editorial Academy of the International Journal of Oncology.) pp. - - issn: 1019-6439 - wos: WOS:000289815800026 (9) - scopus: 2-s2.0-79954993415 (9)
11573/511590 - 2011 -
Apoptotic events are modulated by poly(ADP-ribose)polymerase in cellular and animal models of Alzheimer disease Mosca, Luciana; Fuso, Andrea; Aureli, Cristina; Martire, Sara; Masci, Alessandra; Rotili, Dante; De Leo, Alessandra; Giordano, Cesare Giovanni; Scarpa, Sigfrido; D'erme, Maria - 04a Atto di comunicazione a congresso
libro: Abstract book - ()
11573/511592 - 2011 -
PARP activation modulates apoptosis events in cellular and animal models of Alzheimer disease Mosca, Luciana; Martire, Sara; Fuso, Andrea; D., Beyaie; Masci, Alessandra; Rotili, Dante; De Leo, Alessandra; Consalvi, Valerio; Giordano, Cesare Giovanni; Scarpa, Sigfrido; D'erme, Maria - 04a Atto di comunicazione a congresso
congresso: Molecular Mechanisms of Neurodegeneration (Milan, Italy,)
libro: Abstract book - ()
11573/379664 - 2011 -
Biological Effects of MC2050, a Quinazoline-Based PARP-1 Inhibitor, in Human Neuroblastoma and EBV-Positive Burkitt's Lymphoma Cells Mosca, Luciana; Rotili, Dante; Tempera, Italo; Masci, Alessandra; Fontana, Mario; Chiaraluce, Roberta; Mastromarino, Paola; D'erme, Maria; Mai, Antonello - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 606-611 - issn: 1860-7179 - wos: WOS:000288814900006 (12) - scopus: 2-s2.0-79953056639 (11)
11573/442676 - 2011 -
Photoactivable peptides for identifying enzyme-substrate and protein-protein interactions. Rotili, Dante; Altun, M; Hamed, Rb; Loenarz, C; Thalhammer, A; Hopkinson, Rj; Tian, Ym; Ratcliffe, Pj; Mai, Antonello; Kessler, Bm; Schofield, C. J. - 01a Articolo in rivista
rivista: CHEMICAL COMMUNICATIONS (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 1488-1490 - issn: 1359-7345 - wos: WOS:000286389500026 (5) - scopus: 2-s2.0-78751521073 (5)
11573/442886 - 2011 -
Targeting histone demethylases: A new avenue for the fight against cancer Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
rivista: GENES & CANCER (Thousand Oaks, CA: SAGE Publications) pp. 663-679 - issn: 1947-6019 - wos: (0) - scopus: 2-s2.0-80054787805 (173)
11573/442882 - 2011 -
A Photoreactive Small-Molecule Probe for 2-Oxoglutarate Oxygenases Rotili, Dante; Mikael, Altun; Akane, Kawamura; Alexander, Wolf; Roman, Fischer; I. K., Leung; Mukram M, Mackeen; Ya Min, Tian; Peter J, Ratcliffe; Mai, Antonello; Benedikt M, Kessler; Christopher J, Schofield - 01a Articolo in rivista
rivista: CHEMISTRY & BIOLOGY (Current Science:400 Market Street, Suite 700:Philadelphia, PA 19106:(800)427-1796, (215)574-2266, EMAIL: info@phl.cursci.com, INTERNET: http://www-current-science-group.com, Fax: (215)574-2225) pp. 642-654 - issn: 1074-5521 - wos: WOS:000291499600013 (43) - scopus: 2-s2.0-79957487715 (45)
11573/379781 - 2011 -
Diarylpyrimidine-Dihydrobenzyloxopyrimidine Hybrids: New, Wide-Spectrum Anti-HIV-1 Agents Active at (Sub)-Nanomolar Level. Rotili, Dante; Tarantino, D; Artico, M; Nawrozkij, Mb; Gonzalez Ortega, E; Clotet, B; Samuele, A; Este, Ja; Maga, G; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3091-3096 - issn: 0022-2623 - wos: WOS:000289697800043 (47) - scopus: 2-s2.0-79955455754 (52)
11573/442679 - 2011 -
Simplification of the tetracyclic SIRT1-selective inhibitor MC2141: Coumarin- and pyrimidine-based SIRT1/2 inhibitors with different selectivity profile Rotili, Dante; Vincenzo, Carafa; Domenico, Tarantino; Giorgia, Botta; Angela, Nebbioso; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 3659-3668 - issn: 0968-0896 - wos: WOS:000291477600007 (26) - scopus: 2-s2.0-79958261783 (29)
11573/434969 - 2010 -
HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation A., Nebbioso; C., Dell'aversana; A., Bugge; R., Sarno; Valente, Sergio; Rotili, Dante; F., Manzo; D., Teti; S., Mandrup; P., Ciana; A., Maggi; Mai, Antonello; H., Gronemeyer; L., Altucci - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR ENDOCRINOLOGY (Pubblicata da:
SOC ENDOCRINOLOGY, 22 APEX COURT, WOODLANDS, BRADLEY STOKE, BRISTOL, ENGLAND, BS32 4JT
primo editore:
Journal of Endocrinology Limited:17 18 Courtyard Woodlands, Bristol BS12 4NQ United Kingdom:011 44 117 9616046, EMAIL: sxa15@psu.edu, INTERNET: http://www.psu.edu, Fax: 011 44 117 9616071) pp. 219-228 - issn: 0952-5041 - wos: WOS:000282528800005 (51) - scopus: 2-s2.0-77957824326 (55)
11573/13728 - 2010 -
Proteomic profile of differentially expressed plasma proteins from dystrophic mice and following suberoylanilide hydroxamic acid treatment Colussi, C.; Banfi, C.; Brioschi, M.; Tremoli, E.; Straino, S.; Spallotta, F.; Mai, Antonello; Rotili, Dante; Capogrossi Mc, Gaetano C. - 01a Articolo in rivista
rivista: PROTEOMICS. CLINICAL APPLICATIONS (Weinheim : Wiley-VCH-Verl.) pp. 71-83 - issn: 1862-8346 - wos: WOS:000274264900007 (29) - scopus: 2-s2.0-77951727320 (30)
11573/13666 - 2010 -
The histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces cardiac arrhythmias in dystrophic mice Colussi, C.; Berni, R.; Rosati, J.; Straino, S.; Vitale, S.; Spallotta, F.; Baruffi, S.; Bocchi, L.; Delucchi, F.; Rossi, S.; Savi, M.; Rotili, Dante; Quaini, F.; Macchi, E.; Stilli, D.; Musso, E.; Mai, Antonello; Capogrossi Mc, Gaetano C. - 01a Articolo in rivista
rivista: CARDIOVASCULAR RESEARCH (editore attuale:
ELSEVIER SCIENCE BV, PO BOX 211, AMSTERDAM, NETHERLANDS, 1000 AE
primo editore:
BMJ / British Medical Journal Publishing Group:PO Box 299, London WC1H 9TD United Kingdom:011 44 20 73836270, EMAIL: subscriptions@bmjgroup.com, INTERNET: http://www.bmjpg.com/bmj, Fax: 011 44 20 73836402) pp. 73-82 - issn: 0008-6363 - wos: WOS:000278690000012 (40) - scopus: 2-s2.0-77955165005 (42)
11573/442677 - 2010 -
Characterization of Sirtuin Inhibitors in Nematodes Expressing a Muscular Dystrophy Protein Reveals Muscle Cell and Behavioral Protection by Specific Sirtinol Analogues Matthieu Y., Pasco; Rotili, Dante; Lucia, Altucci; Francesca, Farina; Guy A., Rouleau; Mai, Antonello; Christian, Neri - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1407-1411 - issn: 0022-2623 - wos: WOS:000274270900047 (35) - scopus: 2-s2.0-77249153712 (36)
11573/456124 - 2010 -
The specific character of the reaction of derivatives of 2-thioxo-2,3-dihydropyrimidin-4(1H)-one with iodomethane and alkyl chloromethyl sulfides. Novakov, Ia; Orlinson, B; Nawrozkij, Mb; Mai, Antonello; Artico, Marino; Rotili, Dante; Eremiychuk, As; Gordeeva, Ea; Brunilina, Ll; Este, J. A. - 01a Articolo in rivista
rivista: CHEMISTRY OF HETEROCYCLIC COMPOUNDS (Consultants Bureau:A Division of Plenum Publishing Corporation, 233 Spring Street, Sixth Floor:New York, NY 10013:(800)221-9369, (212)620-8082, Fax: (212)463-0742) pp. - - issn: 0009-3122 - wos: WOS:000279454900010 (1) - scopus: 2-s2.0-77954638922 (0)
11573/895420 - 2010 -
Evaluation of histone deacetylases as drug targets in Huntington's disease models Quinti, Luisa; Chopra, Vanita; Rotili, Dante; Valente, Sergio; Amore, Allison; Franci, Gianluigi; Meade, Sarah; Valenza, Marta; Altucci, Lucia; Maxwell, Michele M.; Cattaneo, Elena; Hersch, Steven; Mai, Antonello; Kazantsev, Aleksey - 02a Capitolo o Articolo
libro: PLOS CURRENTS - ()
11573/456116 - 2010 -
Identification of Tri- and Tetracyclic Pyrimidinediones as Sirtuin Inhibitors Rotili, Dante; Tarantino, Domenico; Vincenzo, Carafa; Ester, Lara; Sarah, Meade; Giorgia, Botta; Angela, Nebbioso; Jorg, Schemies; Manfred, Jung; Aleksey G, Kazantsev; Manel, Esteller; Mario F, Fraga; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 674-677 - issn: 1860-7179 - wos: WOS:000277725100005 (46) - scopus: 2-s2.0-77951697156 (45)
11573/229552 - 2010 -
Nitric oxide determines mesodermic differentiation of mouse embryonic stem cells by activating class IIa histone deacetylases: potential therapeutic implications in a mouse model of hindlimb ischemia Spallotta, F; Rosati, J; Straino, S; Nanni, S; Grasselli, A; Ambrosino, V; Rotili, Dante; Valente, Sergio; Farsetti, A; Mai, Antonello; Capogrossi, Mc; Gaetano, C; Illi, B. - 01a Articolo in rivista
rivista: STEM CELLS (Alphamed Press Incorporated:1 Prestige Place, Suite 290:Miamisburg, OH 45342:(937)291-2355, EMAIL: alphamedpress@alphamedpress.com, INTERNET: http://www.alphamedpress.com, Fax: (937)291-4229) pp. 431-442 - issn: 1066-5099 - wos: WOS:000277093700006 (48) - scopus: 2-s2.0-77950581254 (47)
11573/229551 - 2009 -
Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence Andrea, Savarino; Mai, Antonello; Sandro, Norelli; Sary El, Daker; Valente, Sergio; Rotili, Dante; Lucia, Altucci; Palamara, Anna Teresa; Enrico, Garaci - 01a Articolo in rivista
rivista: RETROVIROLOGY (London : BioMed Central) pp. 52-52 - issn: 1742-4690 - wos: WOS:000267430700001 (96) - scopus: 2-s2.0-67649259174 (97)
11573/13145 - 2009 -
Chiral HPLC separation and absolute configuration of novel S-DABO derivatives. Cirilli, R; Ferretti, R; La Torre, F; Borioni, A; Fares, V; Camalli, M; Faggi, C; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
rivista: CHIRALITY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 604-612 - issn: 0899-0042 - wos: WOS:000267250300007 (10) - scopus: 2-s2.0-67649403720 (11)
11573/456128 - 2009 -
Reactions of 6-benzyl-5-methyl-2-(methylsulfanyl)pyrimidin-4(3H)-one with aliphatic and aliphatic-aromatic amines I. A., Novakov; B. S., Orlinson; Mai, Antonello; Artico, Marino; Rotili, Dante; M. B., Navrotskii; E. A., Gordeeva; E. N., Savel'ev - 01a Articolo in rivista
rivista: RUSSIAN JOURNAL OF ORGANIC CHEMISTRY (pubblicata da:
MAIK NAUKA/INTERPERIODICA, C/O KLUWER ACADEMIC-PLENUM PUBLISHERS, 233 SPRING ST, NEW YORK, USA, NY, 10013-1578) pp. 773-776 - issn: 1070-4280 - wos: WOS:000266829300021 (5) - scopus: 2-s2.0-67049164618 (3)
11573/360909 - 2009 -
Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect. Lara, E; Mai, Antonello; Calvanese, V; Altucci, L; Lopez Nieva, P; Martinez Chantar, Ml; Varela Rey, M; Rotili, Dante; Nebbioso, A; Ropero, S; Montoya, G; Oyarzabal, J; Velasco, S; Serrano, M; Witt, M; Villar Garea, A; Inhof, A; Mato, Jm; Esteller, M; Fraga, Mf - 01a Articolo in rivista
rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 781-791 - issn: 0950-9232 - wos: WOS:000263320000001 (212) - scopus: 2-s2.0-60149091562 (231)
11573/456126 - 2009 -
Stereoselective synthesis of 2-substituted 6-[1-(2,6-difluorophenyl)ethyl]-5-methylpyrimidin-4(3H)-ones. Mai, Antonello; Artico, Marino; Rotili, Dante; Novakov, Ia; Orlinson, Bs; Navrotskii, Mb; Eremiichuk, As; Gordeeva, E. A. - 01a Articolo in rivista
rivista: RUSSIAN JOURNAL OF ORGANIC CHEMISTRY (pubblicata da:
MAIK NAUKA/INTERPERIODICA, C/O KLUWER ACADEMIC-PLENUM PUBLISHERS, 233 SPRING ST, NEW YORK, USA, NY, 10013-1578) pp. 1531-1534 - issn: 1070-4280 - wos: WOS:000271810500019 (1) - scopus: 2-s2.0-70450201365 (0)
11573/361722 - 2009 -
Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases Mai, Antonello; Rotili, Dante; Tarantino, Domenico; Angela, Nebbioso; Sabrina, Castellano; Gianluca, Sbardella; Marc, Tini; Lucia, Altucci - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 1132-1135 - issn: 0960-894X - wos: WOS:000263295200021 (63) - scopus: 2-s2.0-59749103028 (67)
11573/442678 - 2009 -
Histone deacetylase inhibitors and neurodegenerative disorders: Holding the promise Mai, Antonello; Rotili, Dante; Valente, Sergio; Aleksey, Kazantsev - 01a Articolo in rivista
rivista: CURRENT PHARMACEUTICAL DESIGN (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 3940-3957 - issn: 1381-6128 - wos: WOS:000271385600003 (69) - scopus: 2-s2.0-70649108817 (70)
11573/434973 - 2009 -
Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes. Nebbioso, A; Manzo, F; Miceli, M; Conte, M; Manente, L; Baldi, A; De Luca, A; Rotili, Dante; Valente, Sergio; Mai, Antonello; Usiello, A; Gronemeyer, H; Altucci, L. - 01a Articolo in rivista
rivista: EMBO REPORTS (Oxford : Oxford University Press, 2000-) pp. 776-782 - issn: 1469-221X - wos: WOS:000267599700022 (117) - scopus: 2-s2.0-67650083046 (119)
11573/227010 - 2009 -
Non-cancer uses of histone deacetylase inhibitors: effects on infectious diseases and β-hemoglobinopathies Rotili, Dante; Simonetti, Giovanna; A., Savarino; Palamara, Anna Teresa; Migliaccio, A. R.; Mai, Antonello - 01a Articolo in rivista
rivista: CURRENT TOPICS IN MEDICINAL CHEMISTRY (Hilversum : Bentham Science Publishers) pp. 272-291 - issn: 1568-0266 - wos: WOS:000265798300006 (37) - scopus: 2-s2.0-65449142086 (45)
11573/361898 - 2008 -
Histone deacetylase inhibitors and hemoglobin F induction in beta-thalassemia A. R., Migliaccio; Rotili, Dante; A., Nebbioso; G., Atweh; Mai, Antonello - 01a Articolo in rivista
rivista: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 2341-2347 - issn: 1357-2725 - wos: WOS:000259134100002 (12) - scopus: 2-s2.0-48349094044 (16)
11573/363940 - 2008 -
Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases Gianluca, Sbardella; Sabrina, Castellano; Caterina, Vicidomini; Rotili, Dante; Angela, Nebbioso; Marco, Miceli; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 2788-2792 - issn: 0960-894X - wos: WOS:000255444300005 (81) - scopus: 2-s2.0-42949089945 (87)
11573/358405 - 2008 -
Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling Illi, B.; Dello Russo, Claudio; Colussi, C.; Rosati, J.; Pallaoro, M.; Spallotta, F.; Rotili, Dante; Valente, Sergio; Ragone, G.; Martelli, F.; Biglioli, P.; Steinkuhler, C.; Gallinari, P.; Mai, Antonello; Capogrossi, M. C.; Gaetano, C. - 01a Articolo in rivista
rivista: CIRCULATION RESEARCH (Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320
PRimo editore:
Baltimore, Md. : Grune & Stratton, c1953-) pp. 51-58 - issn: 0009-7330 - wos: WOS:000252217400009 (96) - scopus: 2-s2.0-37849010584 (100)
11573/363936 - 2008 -
Novel uracil-based 2-aminoanilide and 2-aminoanilide-like derivatives: Histone deacetylase inhibition and in-cell activities Mai, Antonello; Andrea, Perrone; Angela, Nebbioso; Rotili, Dante; Valente, Sergio; Maria, Tardugno; Silvio, Massa; Floriana De, Bellis; Lucia, Altucci - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 2530-2535 - issn: 0960-894X - wos: WOS:000255246400002 (25) - scopus: 2-s2.0-41849089386 (28)
11573/363647 - 2008 -
5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile. Nawrozkij, Mb; Rotili, Dante; Tarantino, Domenico; Botta, G; Eremiychuk, As; Musmuca, Ira; Ragno, Rino; Samuele, A; Zanoli, S; Armand Ugón, M; Clotet Codina, I; Novakov, Ia; Orlinson, Bs; Maga, G; Esté, Ja; Artico, Marino; Mai, Antonello - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4641-4652 - issn: 0022-2623 - wos: WOS:000258289800033 (53) - scopus: 2-s2.0-49449113636 (57)
11573/365241 - 2008 -
Class II-selective histone deacetylase inhibitors. Part 2: Alignment-independent GRIND 3-D QSAR, homology and docking studies Ragno, Rino; Silvia, Simeoni; Rotili, Dante; Antonella, Caroli; Giorgia, Botta; Gerald, Brosch; Silvio, Massa; Mai, Antonello - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 621-632 - issn: 0223-5234 - wos: WOS:000254777400019 (38) - scopus: 2-s2.0-40049110686 (46)
11573/362098 - 2008 -
Substrate-induced stable enzyme-inhibitor complex formation allows tight binding of novel 2-aminopyrimidin-4(3H)-ones to drug-resistant HIV-1 reverse transcriptase mutants. Samuele, A; Facchini, M; Rotili, Dante; Mai, Antonello; Artico, Marino; Armand Ugón, M; Esté, Ja; Maga, G. - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1412-1418 - issn: 1860-7179 - wos: WOS:000259628300014 (9) - scopus: 2-s2.0-54849438319 (9)
11573/363321 - 2007 -
Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains Mai, Antonello; Artico, Marino; Rotili, Dante; Tarantino, Domenico; Clotet Codina, I; Armand Ugón, M; Ragno, Rino; Simeoni, S; Sbardella, G; Nawrozkij, M. B.; Samuele, A; Maga, G; Esté, J. A. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5412-5424 - issn: 0022-2623 - wos: WOS:000250557100019 (58) - scopus: 2-s2.0-35848949355 (62)
11573/362130 - 2007 -
Identification of two new synthetic histone deacetylase inhibitors that modulate globin gene expression in erythroid cells from healthy donors and patients with thalassemia Mai, Antonello; K., Jelicic; Rotili, Dante; A., Di Noia; E., Alfani; Valente, Sergio; L., Altucci; A., Nebbioso; S., Massa; R., Galanello; G., Brosch; A. R., Migliaccio; G., Migliaccio - 01a Articolo in rivista
rivista: MOLECULAR PHARMACOLOGY (American Society for Pharmacology and Experimental Therapeutics:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7024, EMAIL: pstoute@aspet.org, INTERNET: http://www.aspet.org, Fax: (301)634-7099) pp. 1111-1123 - issn: 0026-895X - wos: WOS:000250385300004 (29) - scopus: 2-s2.0-35548933854 (30)
11573/365178 - 2007 -
Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans Mai, Antonello; Rotili, Dante; Massa, Silvio; Gerald, Brosch; Simonetti, Giovanna; Passariello, Claudio; Palamara, Anna Teresa - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 1221-1225 - issn: 0960-894X - wos: WOS:000244943300017 (79) - scopus: 2-s2.0-33846938126 (84)
11573/364545 - 2007 -
Novel pyrrole-containing histone deacetylase inhibitors endowed with cytodifferentiation activity Mai, Antonello; Valente, Sergio; Rotili, Dante; Silvio, Massa; Giorgia, Botta; Gerald, Brosch; Marco, Miceli; Angela, Nebbioso; Lucia, Altucci - 01a Articolo in rivista
rivista: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 1510-1522 - issn: 1357-2725 - wos: WOS:000248566700025 (14) - scopus: 2-s2.0-34447268739 (14)
11573/51617 - 2007 -
Docking and 3-D QSAR Studies on SIRT2 Inhibitors: A GRID/GOLPE Approach on Different Series of Compounds. Ragno, Rino; Mai, Antonello; Simeoni, Silvia; Caroli, Antonia; Rotili, Dante; Botta, Giorgia - 04a Atto di comunicazione a congresso
congresso: Frontiers in CNS and Oncology Medicinal Chemistry, ACS-EFMC (Siena, Italy)
libro: Frontiers in CNS and Oncology Medicinal Chemistry, ACS-EFMC - ()
11573/361993 - 2007 -
Slow-, tight-binding HIV-1 reverse transcriptase non-nucleoside inhibitors highly active against drug-resistant mutants Reynel, Cancio; Mai, Antonello; Rotili, Dante; Marino, Artico; Gianluca, Sbardella; Imma Clotet, Codina; José A, Este; Emmanuele, Crespan; Samantha, Zanoli; Ulrich, Hubscher; Silvio, Spadari; Giovanni, Maga - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 445-448 - issn: 1860-7179 - wos: WOS:000246011500006 (20) - scopus: 2-s2.0-34547939030 (22)
11573/362194 - 2007 -
Histone deacetylase inhibitors may reduce pathogenicity and virulence in Candida albicans Simonetti, Giovanna; Passariello, Claudio; Rotili, Dante; Mai, Antonello; Enrico, Garaci; Palamara, Anna Teresa - 01a Articolo in rivista
rivista: FEMS YEAST RESEARCH (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1371-1380 - issn: 1567-1356 - wos: WOS:000250298000018 (41) - scopus: 2-s2.0-35448985401 (41)
11573/362375 - 2006 -
Analytical and semipreparative high performance liquid chromatography separation of stereoisomers of novel 3,4-dihydropyrimidin-4(3H)-one derivatives on the immobilised amylose-based Chiralpack IA chiral stationary phase. Cirilli, R; Ferretti, R; Gallinella, B; La Torre, F; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
rivista: JOURNAL OF SEPARATION SCIENCE (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 1399-1406 - issn: 1615-9306 - wos: WOS:000239291200011 (27) - scopus: 2-s2.0-33746470231 (29)
11573/358996 - 2006 -
Small-Molecule Inhibitors of Histone Acetyltransferase Activity: Identification and Biological Properties Mai, A; Rotili, D.; Tarantino, D; Ornaghi, P; Tosi, F; Vicidomini, C; Sbardella, G; Nebbioso, A; Miceli, M; Altucci, L; Filetici, P - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6897-6907 - issn: 0022-2623 - wos: WOS:000241894000031 (121) - scopus: 2-s2.0-33750989910 (128)
11573/12854 - 2006 -
Identification of small molecules inhibitors of GCN5 histone acetyltransferase activity Mai, Antonello; Rotili, Dante; Ornaghi, P; Tosi, F; Vicidomini, C; Sbardella, G; Nebbioso, A; Altucci, L; Filetici, P. - 01a Articolo in rivista
rivista: ARKIVOC (ARKAT USA INC, C/O ALAN R KATRITZKY, UNIV FLORIDA, DEPT CHEMISTRY, PO BOX 117200, GAINESVILLE, USA, FL, 32611) pp. 24-37 - issn: 1551-7004 - wos: WOS:000242574600004 (6) - scopus: 2-s2.0-33744470562 (7)
11573/363353 - 2006 -
Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors Mai, Antonello; Silvio, Massa; Rotili, Dante; Silvia, Simeoni; Ragno, Rino; Giorgia, Botta; Angela, Nebbioso; Marco, Miceli; Lucia, Altucci; Gerald, Brosch - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6046-6056 - issn: 0022-2623 - wos: WOS:000240826200019 (59) - scopus: 2-s2.0-33749258885 (57)
11573/366703 - 2006 -
One-Pot, High Yielding Synthesis of Novel Dihydrothiazolo[3,2-a]pyrimidinones Rotili, Dante; Mai, Antonello; Ambrogio, I; G., Fabrizi - 01a Articolo in rivista
rivista: SYNTHETIC COMMUNICATIONS (New York, NY : Taylor & Francis
New York, NY: Marcel Dekker Incorporated) pp. 495-500 - issn: 0039-7911 - wos: WOS:000234819600013 (0) - scopus: 2-s2.0-31744445689 (1)
11573/363623 - 2006 -
6-Alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): Novel Regulators of Cell Differentiation and Proliferation Sbardella, G; Bartolini, S; Castellano, S; Artico, Marino; Paesano, N; Rotili, Dante; Spadafora, C; Mai, Antonello - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1073-1080 - issn: 1860-7179 - wos: WOS:000202946300006 (13) - scopus: 2-s2.0-33750284393 (14)
11573/526020 - 2005 -
Histone Deacetylation in Epigenetics: An Attractive Target for Anticancer Therapy Mai, Antonello; Massa, S; Rotili, Dante; Cerbara, I; Valente, Sergio; Pezzi, R; Simeoni, S; Ragno, Rino - 01a Articolo in rivista
rivista: MEDICINAL RESEARCH REVIEWS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 261-309 - issn: 0198-6325 - wos: WOS:000228224900001 (300) - scopus: 2-s2.0-16844362441 (315)
11573/364675 - 2005 -
Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides Mai, Antonello; Silvio, Massa; Riccardo, Pezzi; Silvia, Simeoni; Rotili, Dante; Angela, Nebbioso; Annamaria, Scognamiglio; Lucia, Altucci; Peter, Loidl; Gerald, Brosch - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3344-3353 - issn: 0022-2623 - wos: WOS:000228871700031 (187) - scopus: 2-s2.0-20944435415 (194)
11573/364679 - 2005 -
Exploring the connection unit in the HDAC inhibitor pharmacophore model: Novel uracil-based hydroxamates Mai, Antonello; Silvio, Massa; Rotili, Dante; Riccardo, Pezzi; Patrizia, Bottoni; Roberto, Scatena; Joachim, Meraner; Gerald, Brosch - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 4656-4661 - issn: 0960-894X - wos: WOS:000232465900002 (43) - scopus: 2-s2.0-25144444434 (48)
11573/363627 - 2005 -
A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast Prisca, Ornaghi; Rotili, Dante; Gianluca, Sbardella; Mai, Antonello; Patrizia, Filetici - 01a Articolo in rivista
rivista: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited
-London ; New York : Pergamon Press, 1958-) pp. 911-917 - issn: 0006-2952 - wos: WOS:000231663100011 (35) - scopus: 2-s2.0-23744453206 (37)
11573/364674 - 2005 -
6-[1-(2,6-difluorophenyl)ethyl]pyrimidinones antagonize cell proliferation and induce cell differentiation by inhibiting (a nontelomeric) endogenous reverse transcriptase Sara, Bartolini; Mai, Antonello; Artico, Marino; Nicola, Paesano; Rotili, Dante; Corrado, Spadafora; Gianluca, Sbardella - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6776-6778 - issn: 0022-2623 - wos: WOS:000233017300003 (51) - scopus: 2-s2.0-27444434731 (51)
11573/189567 - 2004 -
Synthesis and evaluation of sirtinol analogues as yeast Sir2 and human SIRT inhibitors Pezzi, R.; Rotili, D.; Simeoni, S.; Ragno, Rino; Mariotti, Francesca Romana; Chiani, Francesco; Camilloni, Giorgio; Massa, S.; Mai, Antonello - 04a Atto di comunicazione a congresso
libro: XVIII International Symposium on Medicinal Chemistry - ()
11573/366839 - 2003 -
Discovery of (Aryloxo propenyl)pyrrolyl Hydroxyamides as Selective Inhibitors of Class IIa Histone Deacetylase Homologue HD1-A Mai, Antonello; Massa, S.; Pezzi, R.; Rotili, Dante; Loidl, P.; Brosch, G. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4826-4829 - issn: 0022-2623 - wos: WOS:000186347400004 (62) - scopus: 2-s2.0-0242362600 (66)