DANIELA DE BIASE

Professore associato


email: daniela.debiase@uniroma1.it
telefono: 07731757230
edificio: LT007
stanza: 104

BIOSKETCH (per il CV completo e le attività ERASMUS fare riferimento al file scaricabile nel link in alto a destra):
Professore Associato di Biochimica - Sapienza Università di Roma, Dipartimento di Scienze e Biotecnologie Medico Chirurgiche
ASN nel 2021 a Professore Ordinario per BIO10 (Biochimica)

Laureata (con lode) presso l'Università La Sapienza di Roma, mi sono poi trasferita all'Università del Galles, College of Cardiff, Galles (UK) per svolgere ricerche nell' ambito del mio dottorato di ricerca in Biochimica, conseguito nel 1991. Dopo brevi soggiorni di ricerca presso l'Università di Cardiff (UK), il Biozentrum (Basilea, CH) e IPK (Gatersleben, DE) Ho assunto un incarico di ricerca e insegnamento (Ricercatore/Professore assistente) presso l'Università di Roma La Sapienza dove ho continuato la mia carriera scientifica.
Da ricercatore, ho ampliato le mie competenze anche alla biologia molecolare e alla microbiologia, lavorando sulla regolazione trascrizionale e sulla biochimica del sistema Gad, il principale sistema di resistenza agli acidi dell'Escherichia coli (commensale e patogeno) e di altri batteri enterici. Sono anche esperto di enzimi PLP-dipendenti, in particolare glutammato decarbossilasi (GAD) e GABA-transaminasi (GABA-T).

Sono uno dei massimi esperti nel campo delle risposte batteriche allo stress acido e ho scritto recensioni anche molto di recente su invito su riviste prestigiose e libri.
Fino al 16 ottobre 2023 sono stato Chiar e Grant Holder Scientific Representative della COST Action CA18113 "EuroMicropH" (https://www.cost.eu/actions/CA18113; https://euromicroph.eu/), una rete di scienziati provenienti da 33 paesi riuniti attorno al argomento "Understanding and exploiting the impacts of low pH on micro-organisms". L'Azione contava 240 membri.

Ad oggi ho formato nella ricerca oltre 30 studenti Master e supervisionato/co-supervisionato 11 studenti di dottorato.

ATTIVITÀ SCIENTIFICHE:
La mia ricerca è al crocevia tra microbiologia, biochimica/biologia molecolare e biotecnologie.
- Presidente dell'azione COST CA18113 "Understanding and exploiting the impacts of low pH on micro-organisms" (https://www.cost.eu/actions/CA18113), fino al 16 ottobre 2023.
- Esperto nel campo della risposta allo stress acido nei batteri
- Organizzatore di tre meeting dell'EFB sullo stress microbico (Kinsale, IE, aprile 2018; Roma, IT, online novembre 2020; Vienna, AT, settembre 2023).
- Organizzatore del Corso Avanzato Trends in Enzymology and Biocatalysis (Roma, IT, maggio 2019)
- Segretario Generale e Membro del Comitato Organizzatore del Meeting Regionale del World Health Summit (Sapienza, Roma, giugno 2022; https://www.regionalmeetingwhs2022.com/)
- Nel board editoriale delle seguenti riviste internazionali: Molecular Microbiology; Frontiers in Microbiology (Associate Editor, Microbial Physiology and Metabolism Section); Folia Microbiologica, Minerva Biotechnology and Biomolecular Research, Minerva Cardiology and Angiology.

Linee di ricerca e Progetti:
- Microbiologia-Biologia Molecolare: lavoro sulla regolazione trascrizionale e sulla biochimica dei sistemi glutammato e glutammina-dipendenti, i principali sistemi di resistenza agli acidi (AR) nell'Escherichia coli (commensale e patogeno) e in molti altri batteri enterici. Sono attualmente allo studio diverse interconnessioni tra diversi sistemi AR e altri processi fisiologici e legati allo stress (come la persistenza) in E. coli e altri batteri enterici.
In anni più recenti ha anche intrapreso studi su nuovi antimicrobici e sul microbioma nella salute e nelle malattie umane
- Biochimica: Esperto di enzimi PLP-dipendenti, in particolare glutammato decarbossilasi (GAD) e GABA-transaminasi (GABA-T) di origine mammifera e batterica. Le proprietà strutturali e il meccanismo catalitico del GAD sono studiati tramite mutagenesi sito-diretta, espressione e purificazione di varianti ricombinanti, studi cinetici e spettroscopici in combinazione con studi strutturali (questi ultimi in collaborazione).
- Biotecnologia: sfruttamento e ingegneria del GAD per applicazioni biotecnologiche, compresa la sintesi di molecole bioattive. Inoltre sta anche studiando la risposta allo stress acido in E. coli e altre specie batteriche per applicazioni nel settore alimentare e biotecnologico (Azione COST CA18113) nonché il metabolismo batterico per scopi di biorisanamento.
- Sono PI di un PRIN 2022 PNRR su "Investigation on the nanoparticles-driven controlled delivery of antimicrobial peptides to treat dermatological infections", una linea di ricerca sviluppata in collaborazione con il CNR e dermatologi del mio stesso Dipartimento.
- Ho partecipato attivamente al progetto NANO-LC finanziato dalla NATO SPP (2021-2023).
- Sono Work Package Leader di un progetto Erasmus KA2 (Partenariato per la Cooperazione) su eOSCE per l'innovazione digitale nella formazione medica (2022-2024).

Produzione scientifica

11573/1692869 - 2024 - Exploitation of microbial activities at low pH to enhance planetary health
Atasoy, Merve; Álvarez Ordóñez, Avelino; Cenian, Adam; Djukić-Vuković, Aleksandra; Lund, Peter A; Ozogul, Fatih; Trček, Janja; Ziv, Carmit; De Biase, Daniela - 01g Articolo di rassegna (Review)
rivista: FEMS MICROBIOLOGY REVIEWS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0168-6445 - wos: (0) - scopus: 2-s2.0-85186105003 (0)

11573/1701376 - 2024 - On the potential role of naturally occurring carboxylic organic acids as anti-infective agents. Opportunities and challenges
Mira, Nuno Pereira; Marshall, Robert; Pinheiro, Maria Joana F; Dieckmann, Ralf; Dahouk, Sascha Al; Skroza, Nevena; Rudnicka, Karolina; Lund, Peter A; De Biase, Daniela - 01g Articolo di rassegna (Review)
rivista: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (Decker Periodicals Publishing Incorporated:PO Box 620, LCD 1, Hamilton Ontario L8N 3K7 Canada:(800)568-7281, (905)522-7017, EMAIL: info@bcdecker.com, INTERNET: http://www.bcdecker.com, Fax: (888)311-4987 ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND, OXON, OX5 1GB) pp. 119-123 - issn: 1201-9712 - wos: WOS:001185803900001 (0) - scopus: 2-s2.0-85184906540 (0)

11573/1666652 - 2023 - Antibacterial activity of peptide derivatives of phosphinothricin against multidrug-resistant Klebsiella pneumoniae
Demiankova, Marija V.; Giovannercole, Fabio; Khomutov, Maxim A.; Salikhov, Arthur I.; Onillon, Laura; Valuev-Elliston, Vladimir T.; Vasilieva, Byazilya F.; Khurs, Elena N.; Gabrielyan, Nina I.; Kochetkov, Sergey N.; Efremenkova, Olga V.; De Biase, Daniela; Khomutov, Alex R. - 01a Articolo in rivista
rivista: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 1-13 - issn: 1420-3049 - wos: WOS:000932575000001 (2) - scopus: 2-s2.0-85147940943 (2)

11573/1678268 - 2023 - Physical, chemical, and sensory properties of water kefir produced from Aronia melanocarpa juice and pomace
Esatbeyoglu, Tuba; Fischer, Annik; Legler, Alessandra; Oner, Manolya E.; Wolken, Henrik; Köpsel, Magdalena; Ozogul, Yesim; Özyurt, Gülsün; De Biase, Daniela; Ozogul, Fatih - 01a Articolo in rivista
rivista: FOOD CHEMISTRY X ([Amsterdam]: Elsevier B.V.) pp. - - issn: 2590-1575 - wos: WOS:001044050700001 (6) - scopus: 2-s2.0-85153383568 (6)

11573/1689259 - 2023 - A desmethylphosphinothricin dipeptide derivative effectively inhibits Escherichia coli and Bacillus subtilis growth
Khomutov, Maxim A.; Giovannercole, Fabio; Onillon, Laura; Demiankova, Marija V.; Vasilieva, Byazilya F.; Salikhov, Arthur I.; Kochetkov, Sergey N.; Efremenkova, Olga V.; Khomutov, Alex R.; De Biase, Daniela - 01a Articolo in rivista
rivista: BIOMOLECULES (Basel: MDPI) pp. - - issn: 2218-273X - wos: WOS:001122435700001 (0) - scopus: 2-s2.0-85175060479 (0)

11573/1701377 - 2023 - EuroMicropH open meeting. Understanding and exploiting the Impacts of low pH on micro-organisms. Programme and abstracts
Steiger, Matthias; De Biase, Daniela; Lund, Peter - 04b Atto di convegno in volume
congresso: Open Meeting: Understanding and exploiting the impacts of low pH on microorganisms (Vienna, Austria)
libro: EuroMicropH Open Meeting: Understanding and Exploiting the Impacts of Low pH on Micro-organisms. Programme and Abstracts - ()

11573/1685200 - 2023 - White light thermoplasmonic activated gold nanorod arrays enable the photo-thermal disinfection of medical tools from bacterial contamination
Zaccagnini, F.; Radomski, P.; Sforza, M. L.; Ziolkowski, P.; Lim, S. -I.; Jeong, K. -U.; Mikielewicz, D.; Godman, N. P.; Evans, D. R.; Slagle, J. E.; Mcconney, M. E.; De Biase, D.; Petronella, F.; De Sio, L. - 01a Articolo in rivista
rivista: JOURNAL OF MATERIALS CHEMISTRY. B (Cambridge : RSC Publishing, 2012-) pp. 1-14 - issn: 2050-750X - wos: WOS:001016188700001 (3) - scopus: 2-s2.0-85164335812 (4)

11573/1655151 - 2022 - A COST Action on microbial responses to low pH: developing links and sharing resources across the academic-industrial divide
Azizi, Tamir; De Araujo, Laurine Carvalho; Cetecioglu, Zeynep; Clancy, Aisha J; Feger, Marie L; Liran, Oded; O'byrne, Conor; Sanka, Immanuel; Scheler, Ott; Sedlakova-Kadukova, Jana; Ziv, Carmit; De Biase, Daniela; Lund, Peter A - 01a Articolo in rivista
rivista: NEW BIOTECHNOLOGY (Amsterdam : Elsevier Life Science) pp. 64-70 - issn: 1871-6784 - wos: WOS:000870458100001 (1) - scopus: 2-s2.0-85138819464 (1)

11573/1628031 - 2022 - Impact of the gastrointestinal tract microbiota on cardiovascular health and pathophysiology
De Biase, Daniela; Biondi Zoccai, Giuseppe; Gunaydin Akyildiz, Aysenur - 01g Articolo di rassegna (Review)
rivista: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320) pp. 13-30 - issn: 0160-2446 - wos: WOS:000821237600002 (1) - scopus: 2-s2.0-85133260153 (1)

11573/1589596 - 2022 - Landscape of stress response and virulence genes among listeria monocytogenes strains
De Biase, Daniela; Lakicevic, Brankica; Den Besten, Heidy - 01g Articolo di rassegna (Review)
rivista: FRONTIERS IN MICROBIOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. 1-16 - issn: 1664-302X - wos: WOS:000750637800001 (18) - scopus: 2-s2.0-85124087224 (20)

11573/1651587 - 2022 - Microbial stress: From model organisms to applications in food, microbiotechnology and medicine
Djukic-Vukovic, Aleksandra P.; De Biase, Daniela; Adrian Lund, Peter; Pereira Mira, Nuno; Sedlakova-Kadukova:, Jana - 06a Curatela

11573/1643081 - 2022 - Editorial: Microbial stress. From model organisms to application in food, microbiotechnology and medicine
Djukic-Vukovic, Aleksandra P.; Mira, Nuno P.; Sedlakova-Kadukova, Jana; De Biase, Daniela; Lund, Peter A. - 01m Editorial/Introduzione in rivista
rivista: FRONTIERS IN MICROBIOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. 1-3 - issn: 1664-302X - wos: WOS:000823104500001 (0) - scopus: 2-s2.0-85133937047 (0)

11573/1652009 - 2022 - Label-free and reusable antibody-functionalized gold nanorod arrays for the rapid detection of Escherichia coli cells in a water dispersion
Petronella, Francesca; De Biase, Daniela; Zaccagnini, Federica; Verrina, Vanessa; Lim, Seok-In; Jeong, Kwang-Un; Miglietta, Selenia; Petrozza, Vincenzo; Scognamiglio, Viviana; Godman, Nicholas P.; Evans, Dean R.; Mcconney, Michael; De Sio, Luciano - 01a Articolo in rivista
rivista: ENVIRONMENTAL SCIENCE. NANO (Cambridge : Royal Society of Chemistry, 2014- Country of publication UNITED KINGDOM) pp. 3343-3360 - issn: 2051-8161 - wos: WOS:000839596400001 (15) - scopus: 2-s2.0-85136314551 (20)

11573/1474402 - 2021 - Management of chronic stable angina. Modern microbiomedical research provides insights into Traditional Chinese Medicine treatments
De Biase, Daniela; Biondi-Zoccai, Giuseppe; Versaci, Francesco; Frati, Giacomo - 01b Commento, Erratum, Replica e simili
rivista: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320) pp. 421-423 - issn: 0160-2446 - wos: WOS:000658820600002 (0) - scopus: 2-s2.0-85103992492 (0)

11573/1583914 - 2021 - Stress survival islets contribute to clonal and serotype-specific differences in L. monocytogenes
Lakicevic, B; De Biase, D; Velebit, B; Mitrovic, R; Jankovic, V; Milojevic, L; Ruppitsch, W - 04c Atto di convegno in rivista
rivista: IOP CONFERENCE SERIES. EARTH AND ENVIRONMENTAL SCIENCE (IOP electronic journals) pp. - - issn: 1755-1315 - wos: (0) - scopus: 2-s2.0-85120423822 (0)
congresso: 61st International Meat Industry Conference (Zlatibor, Serbia)

11573/1569327 - 2021 - Nanotechnology-based biosensor for the detection of harmful pathogens in potable water
Petronella, F.; De Angelis, M.; De Biase, D.; Lim, S. -I.; Jeong, K. -U.; Godman, N.; Evans, D.; Mcconney, M.; De Sio, L. - 04b Atto di convegno in volume
congresso: 8th IEEE International Workshop on Metrology for AeroSpace, MetroAeroSpace 2021 (Online)
libro: 2021 IEEE International Workshop on Metrology for AeroSpace, MetroAeroSpace 2021 - Proceedings - (978-1-7281-7556-0)

11573/1436346 - 2020 - Enzymatic kinetic resolution of desmethylphosphinothricin indicates that phosphinic group is a bioisostere of carboxyl group
De Biase, Daniela; Cappadocio, Francesca; Pennacchietti, Eugenia; Giovannercole, Fabio; Coluccia, Antonio; Vepsäläinen, Jouko; Khomutov, Alex - 01a Articolo in rivista
rivista: COMMUNICATIONS CHEMISTRY ([London]: [Macmillan Publishers Ltd part of Springer Nature], 2018-) pp. - - issn: 2399-3669 - wos: WOS:000619266000001 (4) - scopus: 2-s2.0-85090780766 (4)

11573/1439124 - 2020 - Microbial stress. From sensing to intracellular and population responses
De Biase, Daniela; Morrissey, John; O'byrne, Conor - 06a Curatela

11573/1422115 - 2020 - Editorial. Microbial stress. From sensing to intracellular and population responses
De Biase, Daniela; O'byrne, Conor; Morrissey, John - 01m Editorial/Introduzione in rivista
rivista: FRONTIERS IN MICROBIOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-302X - wos: WOS:000561674200001 (1) - scopus: 2-s2.0-85089522602 (1)

11573/1438886 - 2020 - Understanding how micro-organisms respond to acid pH is central to their control and successful exploitation
Lund, Peter A.; De Biase, Daniela; Liran, Oded; Scheler, Ott; Mira, Nuno P.; Cetecioglu, Zeynep; Noriega Fernández, Estefania; Bover-Cid, Sara; Hall, Rebecca A.; Sauer, Michael; O'byrne, Conor P. - 01g Articolo di rassegna (Review)
rivista: FRONTIERS IN MICROBIOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-302X - wos: WOS:000579386900001 (77) - scopus: 2-s2.0-85092689804 (91)

11573/1291656 - 2019 - Advanced course trends in enzymology and biocatalysis
De Biase, Daniela - 04b Atto di convegno in volume
congresso: Trends in Enzymology and Biocatalysis (Rome, Italy)
libro: Advanced Course: Trends in Enzymology and Biocatalysis - Programme and Abstracts - (9788894389111)

11573/1316295 - 2019 - Biochemical Insights into Glutamate decarboxylase from Mycobacterium tuberculosis
Giovannercole, Fabio; Blanchard, John; De Biase, Daniela - 04f Poster
congresso: 8th Congress of European Microbiologists - FEMS2019 (Glasgow, Scotland)
libro: ABSTRACT BOOK - 8th Congress of European Microbiologists - FEMS2019 - ()

11573/1320399 - 2019 - Lethality of Brucella microti in a murine model of infection depends on the wbkE gene involved in O-polysaccharide synthesis
Ouahrani-Bettache, Safia; Jiménez De Bagüés, María P.; De La Garza, Jorge; Freddi, Luca; Bueso, Juan P.; Lyonnais, Sébastien; Al Dahouk, Sascha; De Biase, Daniela; Köhler, Stephan; Occhialini, Alessandra - 01a Articolo in rivista
rivista: VIRULENCE (Austin, Tex.: Landes Bioscience) pp. 868-878 - issn: 2150-5594 - wos: WOS:000495016500001 (7) - scopus: 2-s2.0-85074283831 (7)

11573/1316291 - 2019 - The glutamine-depend acid resistance system in neutralophilic bacteria
Pennacchietti, Eugenia; D’Alonzo, Chiara; Freddi, Luca; Occhialini, Alessandra; De Biase, Daniela - 04f Poster
congresso: 8th Congress of European Microbiologists - FEMS2019 (Glasgow, Scotland)
libro: ABSTRACT BOOK: 8th Congress of European Microbiologists - FEMS2019 - ()

11573/1120858 - 2018 - Biochemical characterization of Glutamate decarboxylase from Mycobacterium tuberculosis
Giovannercole, Fabio; Koci, Marcel; Blanchard, John; De Biase, Daniela - 04d Abstract in atti di convegno
congresso: Microbial Stress: from Systems to Molecules and Back (4th International Conference) (Kinsale, Co. Cork, Ireland)
libro: Microbial Stress: from Systems to Molecules and Back - ()

11573/1182908 - 2018 - Effect of temperature, pH and plasmids on in vitro biofilm formation in Escherichia coli
Mathlouthi, Ahmed; Pennacchietti, Eugenia; De Biase, Daniela - 01a Articolo in rivista
rivista: ACTA NATURAE (Moscow : Park-media) pp. 129-132 - issn: 2075-8251 - wos: WOS:000466708100016 (18) - scopus: 2-s2.0-85062973916 (20)

11573/1120864 - 2018 - Glutaminase activity and glutamine-dependent acid resistance in enteric bacteria
Pennacchietti, Eugenia; D’Alonzo, Chiara; Freddi, Luca; Occhialini, Alessandra; De Biase, Daniela - 04d Abstract in atti di convegno
congresso: Microbial Stress: from Systems to Molecules and Back (4th International Conference) (Kinsale, Co. Cork, Ireland)
libro: Microbial Stress: from Systems to Molecules and back - ()

11573/1187111 - 2018 - The glutaminase-dependent acid resistance system. Qualitative and quantitative assays and analysis of its distribution in enteric bacteria
Pennacchietti, Eugenia; D’Alonzo, Chiara; Freddi, Luca; Occhialini, Alessandra; De Biase, Daniela - 01a Articolo in rivista
rivista: FRONTIERS IN MICROBIOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. 1-17 - issn: 1664-302X - wos: WOS:000450176900001 (28) - scopus: 2-s2.0-85056695409 (31)

11573/1020435 - 2017 - Role of the glutamine-dependent acid resistance system of Brucella spp. in response to extreme acid stress
Freddi, Luca; Damiano Maria, Alessandra; Pennacchietti, Eugenia; Köhler, Stephan; De Biase, Daniela; Occhialini, Alessandra - 04d Abstract in atti di convegno
congresso: FEMS 2017, 7th Congress of European Microbiologists (Valencia (Spain))
libro: FEMS 2017, 7th Congress of European Microbiologists - ()

11573/1018245 - 2017 - The Glutaminase-dependent system confers extreme acid resistance to new species and atypical strains of Brucella
Freddi, Luca; Damiano, Maria A.; Chaloin, Laurent; Pennacchietti, Eugenia; Al Dahouk, Sascha; Köhler, Stephan; De Biase, Daniela; Occhialini, Alessandra - 01a Articolo in rivista
rivista: FRONTIERS IN MICROBIOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-302X - wos: WOS:000415145100001 (9) - scopus: 2-s2.0-85034031931 (10)

11573/955970 - 2017 - On the effect of alkaline pH and cofactor availability in the conformational and oligomeric state of Escherichia coli glutamate decarboxylase
Giovannercole, Fabio; Mérigoux, C; Zamparelli, Carlotta; Verzili, Daniela; Grassini, Gaia; Buckle, M; Vachette, P; De Biase, Daniela - 01a Articolo in rivista
rivista: PROTEIN ENGINEERING, DESIGN & SELECTION (Oxford : Oxford University Press) pp. 235-244 - issn: 1741-0134 - wos: WOS:000401753500012 (3) - scopus: 2-s2.0-85019684999 (3)

11573/1020433 - 2017 - Biochemical characterization of a variant of Escherichia coli glutamate decarboxylase with improved GABA production at alkaline pH.
Giovannercole, Fabio; Pennacchietti, Eugenia; De Biase, Daniela - 04d Abstract in atti di convegno
congresso: FEMS2017: 7th Congress of European Microbiologists (Valencia (Spain))
libro: FEMS2017: 7th Congress of European Microbiologists - ()

11573/954770 - 2017 - Glutamate decarboxylase in bacteria
Giovannercole, Fabio; Pennacchietti, Eugenia; De Biase, Daniela - 02a Capitolo o Articolo
libro: The Handbook of Microbial Metabolism of Amino Acids - (9781780647234)

11573/954768 - 2017 - The yhiM gene codes for an inner membrane protein involved in GABA export in Escherichia coli
Tramonti, Angela; De Santis, Fiorenzo; Pennacchietti, Eugenia; De Biase, Daniela - 01a Articolo in rivista
rivista: AIMS MICROBIOLOGY (Springfield, MO : AIMS Press, [2015]-) pp. 71-87 - issn: 2471-1888 - wos: WOS:000396631200006 (3) - scopus: 2-s2.0-85056717936 (2)

11573/956175 - 2016 - The role of an active site aspartate residue in the catalytic activity of Glutamate decarboxylase from Escherichia coli.
Giovannercole, Fabio; Pennacchietti, Eugenia; Grassini, Gaia; De Biase, Daniela - 04d Abstract in atti di convegno
congresso: The biochemistry and chemistry of biocatalysis: From understanding to design (Oulu, Finlandia)
libro: The biochemistry and chemistry of biocatalysis: From understanding to design - ()

11573/954766 - 2016 - Convenient syntheses of phosphinic analogues of γ-aminobutyric- and glutamic acids
Khomutov, M. A.; Formanovsky, A. A.; Mikhura, I. V.; Vepsalainen, J.; Kochetkov, S. N.; De Biase, Daniela; Khomutov, A. R. - 01a Articolo in rivista
rivista: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY (Consultants Bureau:A Division of Plenum Publishing Corporation, 233 Spring Street, Sixth Floor:New York, NY 10013:(800)221-9369, (212)620-8082, Fax: (212)463-0742) pp. 672-676 - issn: 1068-1620 - wos: WOS:000393044600012 (2) - scopus: 2-s2.0-85010065516 (2)

11573/954769 - 2016 - Acid survival mechanisms in neutralophilic bacteria
Pennacchietti, Eugenia; Giovannercole, Fabio; De Biase, Daniela - 02a Capitolo o Articolo
libro: Stress and environmental regulation of gene expression and adaptation in bacteria - (9781119004813; 9781119004882)

11573/880563 - 2016 - Bicyclic γ-amino acids as inhibitors of γ-aminobutyrate aminotransferase
Pinto, Andrea; Tamborini, Lucia; Pennacchietti, Eugenia; Coluccia, Antonio; Silvestri, Romano; Cullia, Gregorio; De Micheli, Carlo; Conti, Paola; De Biase, Daniela - 01a Articolo in rivista
rivista: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 295-301 - issn: 1475-6366 - wos: WOS:000368719800014 (13) - scopus: 2-s2.0-84955443104 (13)

11573/1020428 - 2015 - Role of the glutamate decarboxylase(GAD)-dependent system of Brucella spp. in the resistance to extreme acid stess
Damiano Maria, Alessandra; Freddi, Luca; Bastianelli, Daniela; Pennacchietti, Eugenia; Al Dahouk, Sascha; Köhler, Stephan; De Biase, Daniela; Occhialini, Alessandra - 04d Abstract in atti di convegno
congresso: Microbial Stress: from Molecules to Systems (Sitges (Spain))
libro: Microbial Stress: from Molecules to Systems - ()

11573/954765 - 2015 - The Escherichia coli acid stress response and its significance for pathogenesis
De Biase, Daniela; Lund, Peter A. - 01g Articolo di rassegna (Review)
rivista: ADVANCES IN APPLIED MICROBIOLOGY (New York, Academic Press, 1959-) pp. 49-88 - issn: 0065-2164 - wos: WOS:000405620400002 (46) - scopus: 2-s2.0-84942410842 (47)

11573/780412 - 2015 - Biochemical and spectroscopic properties of Brucella microti glutamate decarboxylase, a key component of the glutamate-dependent acid resistance system
Grassini, Gaia; Pennacchietti, Eugenia; F., Cappadocio; A., Occhialini; De Biase, Daniela - 01a Articolo in rivista
rivista: FEBS OPENBIO (Amsterdam : Elsevier) pp. 209-218 - issn: 2211-5463 - wos: WOS:000366999300027 (11) - scopus: 2-s2.0-84925457556 (10)

11573/657065 - 2015 - Glutamate decarboxylase-dependent acid resistance in Brucella spp.. Distribution and contribution to fitness under extremely acidic conditions
M. A., Damiano; Bastianelli, Daniela; S., Al Dahouk; S., Kohler; A., Cloeckaert; De Biase, Daniela; A., Occhialini - 01a Articolo in rivista
rivista: APPLIED AND ENVIRONMENTAL MICROBIOLOGY ([Washington]: American Society for Microbiology) pp. 578-586 - issn: 0099-2240 - wos: WOS:000347377500013 (33) - scopus: 2-s2.0-84920712672 (34)

11573/556744 - 2014 - Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis
Itamar, Kass; David E., Hoke; M. G. S., Costa; Cyril F., Reboul; B. T., Porebski; N. P., Cowieson; Herve, Leh; Pennacchietti, Eugenia; J., Mccoey; Oded, Kleifeld; Carla Borri, Voltattorni; David, Langley; Brendan, Roome; Ian R., Mackay; Daniel, Christ; David, Perahia; M., Buckle; Paiardini, Alessandro; De Biase, Daniela; A. M., Buckle - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. E2524-E2529 - issn: 0027-8424 - wos: WOS:000337760600005 (31) - scopus: 2-s2.0-84903461226 (33)

11573/556736 - 2014 - Coping with low pH. Molecular strategies in neutralophilic bacteria
Peter, Lund; Tramonti, Angela; De Biase, Daniela - 01g Articolo di rassegna (Review)
rivista: FEMS MICROBIOLOGY REVIEWS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1091-1125 - issn: 0168-6445 - wos: WOS:000345075600002 (306) - scopus: 2-s2.0-84924930823 (333)

11573/639210 - 2014 - Role oƒ GABA metabolism enzymes during stress, aging and apoptosis in budding yeast, Saccharomyces cerevisiae
Stirpe, Mariarita; Palermo, Vanessa; A., Tramonti; De Biase, Daniela; Mazzoni, Cristina - 04a Atto di comunicazione a congresso
congresso: 10th International Meeting on Yeast Apoptosis (IMYA) (Goeborg (Sweden))
libro: 10th International Meeting on Yeast Apoptosis (IMYA) - ()

11573/556937 - 2013 - `Some like it acid': how Escherichia coli glutamate decarboxylase controls its intracellular activity in response to acid stress
De Biase, Daniela - 04c Atto di convegno in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 92-93 - issn: 1742-4658 - wos: WOS:000325919200294 (0) - scopus: (0)
congresso: 38th Congress of the Federation-of-European-Biochemical-Societies (FEBS) (Saint Petersburg, RUSSIA)

11573/502098 - 2013 - The elusive but pathogenic peptidoglycan of chlamydiae
Di Pietro, Marisa; De Santis, Fiorenzo; De Biase, Daniela; Sessa, Rosa - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF INFLAMMATION (Biolife, Silvi Marina) pp. 257-260 - issn: 1721-727X - wos: WOS:000318128100026 (7) - scopus: 2-s2.0-84879990055 (6)

11573/540617 - 2013 - Biochemical characterization of glutamic acid decarboxylase from Brucella microti
Grassini, Gaia; Pennacchietti, Eugenia; De Biase, Daniela - 04d Abstract in atti di convegno
congresso: 25a Riunione Nazionale "A. Castellani" dei Dottorandi di Ricerca in Discipline Biochimiche (Brallo di Pregola (PV))
libro: 25a Riunione Nazionale "A. Castellani" dei Dottorandi di Ricerca in Discipline Biochimiche - ()

11573/479452 - 2012 - The Glutamic Acid Decarboxylase System of the New Species Brucella microti Contributes to Its Acid Resistance and to Oral Infection of Mice
A., Occhialini; M. P., Jimenez De Bagues; B., Saadeh; Bastianelli, Daniela; N., Hanna; De Biase, Daniela; S., Kohler - 01a Articolo in rivista
rivista: THE JOURNAL OF INFECTIOUS DISEASES (University of Chicago Press:PO Box 37005, Journals Division:Chicago, IL 60637:(877)705-1878, (877)705-1878, (773)753-2247, EMAIL: subscriptions@press.uchicago.edu, INTERNET: http://www.press.uchicago.edu, Fax: (877)705-1879, (773)753-0811) pp. 1424-1432 - issn: 0022-1899 - wos: WOS:000309930700015 (28) - scopus: 2-s2.0-84867540124 (29)

11573/508757 - 2012 - C–C Bond Formation and Decarboxylation
Bonamore, Alessandra; Macone, Alberto; Kroutil, Wolfgang; Seisser, Birgit; Lammens, Tijs M.; De Biase, Daniela; Franssen, Maurice C. R.; Scott, Elinor L.; Sanders, Johan P. M.; Miyamoto, Kenji; Kourist, Robert; Yoshida, Shosuke; Ohta, Hiromichi; Tian, Jie; Li, Heng; Gao, Wen-Yun; Shanmuganathan, Saravanakumar; Natalia, D.; Greiner, Lasse; Domínguez De Maria, Pablo; He, Yan-Hong; Guan, Zhi; Cai, Jian-Feng - 02a Capitolo o Articolo
libro: Practical Methods for Biocatalysis and Biotransformations 2 - (9781119943426; 9781119991397)

11573/512467 - 2012 - What makes E. coli glutamate decarboxylase an amazing object for basic and biotech research
De Biase, Daniela - 04d Abstract in atti di convegno
congresso: Trends in Enzymology (4th Edition) (Gottingen)
libro: Trends in Enzymology (4th Edition) - ()

11573/512470 - 2012 - Beyond acid resistance: identification of novel targets of the regulators of the gad system in Escherichia coli
De Biase, Daniela - 04d Abstract in atti di convegno
congresso: Microbial stress from Molecules to Systems (2nd International Conference) (Belgirate (Italy))
libro: Microbial stress from Molecules to Systems (2nd International Conference) - ()

11573/481058 - 2012 - Glutamate decarboxylase-dependent acid resistance in orally acquired bacteria: Function, distribution and biomedical implications of the gadBC operon
De Biase, Daniela; Pennacchietti, Eugenia - 01a Articolo in rivista
rivista: MOLECULAR MICROBIOLOGY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 770-786 - issn: 0950-382X - wos: WOS:000311605600003 (121) - scopus: 2-s2.0-84871726559 (127)

11573/474245 - 2012 - Analysis of gene expression in penicillin G induced persistence of Chlamydia pneumoniae
Di Pietro, Marisa; A., Tramonti; De Santis, Fiorenzo; De Biase, Daniela; Schiavoni, Giovanna; Filardo, Simone; Zagaglia, Carlo; Sessa, Rosa - 01a Articolo in rivista
rivista: JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS (Wichtig Editore:Via Friuli 72 74, I 20135 Milan Italy:011 39 02 5455122, 011 39 2 55195443, EMAIL: info@wichtig-publisher.com, INTERNET: http://www.wichtig-publisher.com, Fax: 011 39 2 55195971) pp. 277-284 - issn: 0393-974X - wos: WOS:000307034900013 (20) - scopus: 2-s2.0-84865028130 (20)

11573/512466 - 2012 - Unusual structural and spectroscopic properties of an alanine transaminase from Escherichia coli
Grassini, Gaia; Pennacchietti, Eugenia; De Biase, Daniela - 04d Abstract in atti di convegno
congresso: Trends in Enzymology 2012 (4th Edition) (Gottingen)
libro: Trends in Enzymology 2012 (4th Edition) - ()

11573/423521 - 2012 - Endangered North Atlantic right whales (Eubalaena glacialis) experience repeated, concurrent exposure to multiple environmental neurotoxins produced by marine algae
Gregory J., Doucette; Christina M., Mikulski; Kristen L., King; Patricia B., Roth; Zhihong, Wang; Leandro, Lf; Stacey L., Degrasse; Kevin D., White; De Biase, Daniela; Roxanne M., Gillett; Rosalind M., Rolland - 01a Articolo in rivista
rivista: ENVIRONMENTAL RESEARCH (Amsterdam: Elsevier Orlando, FL: Academic Press Incorporated) pp. 67-76 - issn: 0013-9351 - wos: WOS:000299804800008 (35) - scopus: 2-s2.0-84856211933 (39)

11573/484406 - 2012 - Intracellular NADPH Levels Affect the Oligomeric State of the Glucose 6-Phosphate Dehydrogenase
Saliola, Michele; Tramonti, A.; Lanini, Claudio; Cialfi, S.; De Biase, Daniela; Falcone, Claudio - 01a Articolo in rivista
rivista: EUKARYOTIC CELL (WASHINGTON, USA: AMER SOC MICROBIOLOGY) pp. 1503-1511 - issn: 1535-9778 - wos: WOS:000311778600008 (19) - scopus: 2-s2.0-84870436960 (23)

11573/69672 - 2011 - Activators of the Glutamate-Dependent Acid Resistance System Alleviate Deleterious Effects of YidC Depletion in Escherichia coli
Z., Yu; M., Bekker; A., Tramonti; G. M., Cook; P., Van Ulsen; D. J., Scheffers; J., Teixeira De Mattos; De Biase, Daniela; J., Luirink - 01a Articolo in rivista
rivista: JOURNAL OF BACTERIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 1308-1316 - issn: 0021-9193 - wos: WOS:000287696100003 (6) - scopus: 2-s2.0-79952381058 (6)

11573/417538 - 2010 - Glutamate-based acid resistance in Escherichia coli: biochemical and regulatory aspects
De Biase, Daniela - 04d Abstract in atti di convegno
congresso: Society for general microbiology Autumn meeting 2010 (University of Nottingham, Jubilee Campus)

11573/538608 - 2009 - ASPETTI MOLECOLARI DELLA FORMA PERSISTENTE DI CHLAMYDIA PNEUMONIAE
De Santis, Fiorenzo; Schiavoni, Giovanna; Di Pietro, Marisa; De Biase, Daniela; A., Tramonti; Zagaglia, Carlo; Del Piano, Massimo; Sessa, Rosa - 04b Atto di convegno in volume
congresso: 37° Congresso della Società Italiana di Microbiologia SIM (Torino)
libro: Bollettino della SIM - ()

11573/364628 - 2009 - Mutation of His465 alters the pH-dependent spectroscopic properties of Escherichia coli glutamate decarboxylase and broadens the range of its activity towards more alkaline pH.
Pennacchietti, Eugenia; Lammens, Tm; Capitani, G; Franssen, Mc; John, Ra; Bossa, Francesco; De Biase, Daniela - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 31587-31596 - issn: 0021-9258 - wos: WOS:000271572700013 (43) - scopus: 2-s2.0-70450233413 (48)

11573/49558 - 2009 - The application of glutamic acid alpha-decarboxylase for the valorization of glutamic acid
T. M., Lammens; De Biase, Daniela; Mcr, Franssen; E. L., Scott; Jpm, Sanders - 01a Articolo in rivista
rivista: GREEN CHEMISTRY (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 1562-1567 - issn: 1463-9262 - wos: WOS:000270542400014 (89) - scopus: 2-s2.0-70350041751 (90)

11573/227185 - 2008 - Transcription of the Listeria monocytogenes fri gene is growth-phase dependent and is repressed directly by Fur, the ferric uptake regulator
Francesca, Fiorini; Stefanini, Simonetta; Valenti, Piera; Chiancone, Emilia; De Biase, Daniela - 01a Articolo in rivista
rivista: GENE (Amsterdam Netherlands: Elsevier BV) pp. 113-121 - issn: 0378-1119 - wos: WOS:000254727200015 (28) - scopus: 2-s2.0-40649086144 (27)

11573/362030 - 2008 - GadX/GadW-dependent regulation of the Escherichia coli acid fitness island: transcriptional control at the gadY-gadW divergent promoters and identification of four novel 42 bp GadX/GadW-specific binding sites.
Tramonti, A; De Canio, M; De Biase, Daniela - 01a Articolo in rivista
rivista: MOLECULAR MICROBIOLOGY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 965-982 - issn: 0950-382X - wos: WOS:000260194300017 (86) - scopus: 2-s2.0-54249135920 (95)

11573/419188 - 2006 - Expression of frm, the gene encoding for Listeria monocytogenes Dps (DNA Binding Protein from Starved Cells) is influenced by iron availability and is repressed by the ferric uptake regulator, Fur.
F., Fiorini; De Biase, Daniela; C., Morea; Valenti, Piera; Chiancone, Emilia; Stefanini, Simonetta - 04d Abstract in atti di convegno
congresso: Molecular Microbiology: Dynamics, Evolution and Expression of Prokaryotic Genomes (Heidelberg, Germany)

11573/363998 - 2006 - Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Heinz, Gut; Pennacchietti, Eugenia; John, Ra; Bossa, Francesco; Guido, Capitani; De Biase, Daniela; M. G., Gruetter - 01a Articolo in rivista
rivista: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 2643-2651 - issn: 0261-4189 - wos: WOS:000238709400036 (87) - scopus: 2-s2.0-33745752814 (85)

11573/365236 - 2006 - Mechanism of transcription activation exerted by GadX and GadW at the gadA and gadBC gene promoters of the glutamate-based acid resistance system in Escherichia coli
Tramonti, A; De Canio, M; Delany, I; Scarlato, V; De Biase, Daniela - 01a Articolo in rivista
rivista: JOURNAL OF BACTERIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 8118-8127 - issn: 0021-9193 - wos: WOS:000242275600016 (56) - scopus: 2-s2.0-33751555223 (60)

11573/69669 - 2005 - Structural model of human GAD65: prediction and interpretation of biochemical and immunological features
Capitani, G; De Biase, Daniela; Gut, H; Ahmed, S; Gruetter, Mg - 01a Articolo in rivista
rivista: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 7-14 - issn: 0887-3585 - wos: WOS:000227360600002 (10) - scopus: 2-s2.0-14744273934 (10)

11573/419574 - 2005 - THE GLUTAMATE-BASED ACID RESISTANCE SYSTEM IN ESCHERICHIA COLI: CHARACTERIZATION OF THE TWO MAJOR STRUCTURAL COMPONENTS
De Biase, Daniela; C., Aurizi; Pennacchietti, Eugenia; Bossa, Francesco; G., Capitani; H., Gut; M. G., Gruetter; R. A., John - 04d Abstract in atti di convegno
congresso: 1st International Conference on Environmental, Industrial and Applied Microbiology (Badajoz, Spain)

11573/69670 - 2005 - Antagonistic role of H-NS and GadX in the regulation of the glutamate decarboxylase-dependent acid resistance system in Escherichia coli
M., Giangrossi; S., Zattoni; A., Tramonti; De Biase, Daniela; M., Falconi - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 21498-21505 - issn: 0021-9258 - wos: WOS:000229438800071 (45) - scopus: 2-s2.0-20444417420 (47)

11573/12292 - 2004 - Structures of GABA aminotransferase, a pyridoxal 5'-phosphate and [2Fe-2S] cluster containing enzyme, complexed with -EthynylGABA and with the antiepilepsy drug vigabatrin.
Storici, P; De Biase, Daniela; Bossa, Francesco; Bruno, S; Mozzarelli, A; Peneff, C; Silverman R., B; Schirmer, T. - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 363-373 - issn: 0021-9258 - wos: WOS:000187555300044 (123) - scopus: 2-s2.0-0347052772 (135)

11573/360271 - 2003 - Stability and oligomerization of recombinant GadX, a transcriptional activator of the Escherichia coli glutamate decarboxylase system
A., Tramonti; M., De Canio; Bossa, Francesco; De Biase, Daniela - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (Tokyo ; Oxford ; New York ; London ; Amsterdam ; Shannon ; Paris : Elsevier) pp. 376-380 - issn: 1570-9639 - wos: WOS:000182549400063 (16) - scopus: 2-s2.0-0037974543 (17)
congresso: 3rd International Symposium on Vitamin B6, PQQ, Carbonyl Catalysis and Quinoproteins (SOUTHAMPTON, ENGLAND)

11573/254178 - 2003 - Crystal structure and functional analysis of Escherichia coli glutamate decarboxylase
G., Capitani; De Biase, Daniela; C., Aurizi; H., Gut; Bossa, Francesco; M. G., Gruetter - 01a Articolo in rivista
rivista: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 4027-4037 - issn: 0261-4189 - wos: WOS:000184784100001 (185) - scopus: 2-s2.0-0041465717 (192)

11573/254798 - 2003 - The critical structural role of a highly conserved histidine residue in group II amino acid decarboxylases
Guido, Capitani; Angela, Tramonti; Bossa, Francesco; Markus G., Grutter; De Biase, Daniela - 01a Articolo in rivista
rivista: FEBS LETTERS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 41-44 - issn: 0014-5793 - wos: WOS:000186444000008 (9) - scopus: 2-s2.0-0142184508 (9)

11573/251239 - 2002 - The expression of the dodecameric ferritin in Listeria spp. is induced by iron limitation and stationary growth phase
Mario, Polidoro; De Biase, Daniela; Benedetta, Montagnini; Laura, Guarrera; Stefano, Cavallo; Valenti, Piera; Stefanini, Simonetta; Chiancone, Emilia - 01a Articolo in rivista
rivista: GENE (Amsterdam Netherlands: Elsevier BV) pp. 121-128 - issn: 0378-1119 - wos: WOS:000178785300013 (38) - scopus: 2-s2.0-0037151781 (38)

11573/256146 - 2002 - Contribution of Lys276 to the conformational flexibility of the active site of glutamate decarboxylase from Escherichia coli
Tramonti, A.; John, R. A.; Bossa, Francesco; De Biase, Daniela - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF BIOCHEMISTRY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 4913-4920 - issn: 0014-2956 - wos: WOS:000178608400001 (20) - scopus: 2-s2.0-0036411892 (20)

11573/365378 - 2002 - Functional characterization and regulation of gadX, a gene encoding an AraCXylS-like transcriptional activator of the Escherichia coli glutamic acid decarboxylase system
Tramonti, A; Visca, P; M., De Canio; Falconi, M; De Biase, Daniela - 01a Articolo in rivista
rivista: JOURNAL OF BACTERIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 2603-2613 - issn: 0021-9193 - wos: WOS:000175415800005 (117) - scopus: 2-s2.0-0036237890 (120)

11573/50375 - 2001 - Allosteric communication of tryptophan synthase: functional and regulatory properties of the betaSer178Pro mutant.
Marabotti, A; De Biase, Daniela; Tramonti, A; Bettati, S; Mozzarelli, A. - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 17747-17753 - issn: 0021-9258 - wos: WOS:000168866500019 (28) - scopus: 2-s2.0-0035947566 (28)

11573/136346 - 2000 - GABA-aminotransferase, a target for antiepileptic drug therapy.
Storici, P.; Capitani, G.; De Biase, Daniela; John, R. A.; Jansonius, J. N.; Schirmer, T. - 02a Capitolo o Articolo
libro: Biochemistry and Molecular Biology of Vitamin B6 and PQQ Dependent Proteins - (9783764361457)

11573/248116 - 2000 - Environmental stimuli and regulatory factors affecting the expression of the glutamic acid decarboxylase system in Escherichia coli
Tramonti, A; Visca, P; Bossa, Francesco; De Biase, Daniela - 02a Capitolo o Articolo
libro: Biochemistry and Molecular Biology of Vitamin B6 and PQQ dependent proteins - (9783764361457)

11573/257247 - 1999 - The response to stationary-phase stress conditions in Escherichia coli: role and regulation of the glutamic acid decarboxylase system
De Biase, Daniela; Angela, Tramonti; Bossa, Francesco; Paolo, Visca - 01a Articolo in rivista
rivista: MOLECULAR MICROBIOLOGY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 1198-1211 - issn: 0950-382X - wos: WOS:000081174600009 (215) - scopus: 2-s2.0-0033037702 (233)

11573/241743 - 1999 - Expression and activity of cyclic and linear analogues of esculentin-1, an antimicrobial peptide from amphibian skin.
Ponti, Donatella; Mignogna, Giuseppina; Mangoni, Maria Luisa; De Biase, Daniela; Simmaco, Maurizio; Barra, Donatella - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF BIOCHEMISTRY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 921-927 - issn: 0014-2956 - wos: WOS:000081810900037 (53) - scopus: 2-s2.0-0033178536 (56)

11573/393739 - 1999 - Crystal structure of GABA-aminotransferase, a target for antiepileptic drug therapy.
Storici, P; Capitani, G; De Biase, Daniela; Moser, M; John, Ra; Jansonius, Jn; Schirmer, T. - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 8628-8634 - issn: 0006-2960 - wos: WOS:000081440400005 (77) - scopus: 2-s2.0-0033529338 (85)

11573/247395 - 1998 - The roles of His-167 and His-275 in the reaction catalyzed by glutamate decarboxylase from Escherichia coli
A., Tramonti; De Biase, Daniela; A., Giartosio; Bossa, Francesco; John, Ra - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 1939-1945 - issn: 0021-9258 - wos: WOS:000071595200017 (16) - scopus: 2-s2.0-0031936207 (16)

11573/245005 - 1998 - Purification and characterization of recombinant rabbit cytosolic serine hydroxymethyltransferase
Di Salvo, Martino Luigi; S., Delle Fratte; De Biase, Daniela; Bossa, Francesco; Verne, Schirch - 01a Articolo in rivista
rivista: PROTEIN EXPRESSION AND PURIFICATION (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445 ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, USA, CA, 92101-4495) pp. 177-183 - issn: 1046-5928 - wos: WOS:000074951500006 (25) - scopus: 2-s2.0-0032126946 (25)

11573/247032 - 1998 - CRYSTALLIZATION AND PRELIMINARY X-RAY ANALYSIS OF THE BETA-ISOFORM OF GLUTAMATE DECARBOXYLASE FROM ESCHERICHIA COLI.
Malashkevich, Vn; De Biase, Daniela; Markovic Housley, Z; Schlunegger, Mp; Bossa, Francesco; Jansonius, Jn - 01a Articolo in rivista
rivista: ACTA CRYSTALLOGRAPHICA. SECTION D, BIOLOGICAL CRYSTALLOGRAPHY (Blackwell Munksgaard:PO Box 2148, Periodicals Department, DK-1016 Copenhagen K Denmark:011 45 33 755913, EMAIL: agentservices@oxon.blackwellpublishing.com, INTERNET: http://www.blackwellmunksgaard.com, Fax: 011 45 77 333377) pp. 1020-1022 - issn: 0907-4449 - wos: WOS:000075952200042 (5) - scopus: 2-s2.0-0032169851 (5)

11573/247394 - 1996 - Isolation, overexpression, and biochemical characterization of the two isoforms of glutamic acid decarboxylase from Escherichia coli
De Biase, Daniela; A., Tramonti; John, Ra; Bossa, Francesco - 01a Articolo in rivista
rivista: PROTEIN EXPRESSION AND PURIFICATION (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445 ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, USA, CA, 92101-4495) pp. 430-438 - issn: 1046-5928 - wos: WOS:A1996VX14300006 (87) - scopus: 2-s2.0-0030470440 (92)

11573/75300 - 1996 - Half-site reactivity of bovine serum amine oxidase. Chemical identity of two sites.
De Biase, Daniela; Agostinelli, Enzo; De Matteis, G.; Mondovi', Bruno; Morpurgo, L. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF BIOCHEMISTRY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 93-99 - issn: 0014-2956 - wos: WOS:A1996UD77400011 (31) - scopus: 2-s2.0-0029944727 (34)

11573/50380 - 1995 - PRIMARY STRUCTURE AND TISSUE DISTRIBUTION OF HUMAN 4-AMINOBUTYRATE AMINOTRANSFERASE
De Biase, Daniela; Barra, Donatella; Simmaco, Maurizio; John, Ra; Bossa, Francesco - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF BIOCHEMISTRY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 476-480 - issn: 0014-2956 - wos: WOS:A1995QB85100059 (26) - scopus: 2-s2.0-0028832108 (26)

11573/384161 - 1995 - Active site model for gamma-aminobutyrate aminotransferase explains substrate specificity and inhibitor reactivities
Toney, Md; Pascarella, Stefano; De Biase, Daniela - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. 2366-2374 - issn: 0961-8368 - wos: WOS:A1995TE28700015 (21) - scopus: 2-s2.0-0028783806 (28)

11573/50382 - 1993 - Sequence studies on pyridoxal phosphate-dependent enzymes.
Bossa, Francesco; Maras, Bruno; De Biase, Daniela; John, Ra; Barra, Donatella - 01a Articolo in rivista
rivista: BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY (Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331) pp. 143-148 - issn: 0885-4513 - wos: WOS:A1993MB80100004 (2) - scopus: 2-s2.0-84982000880 (2)

11573/50383 - 1993 - Isolation and cloning of the gene from Escherichia coli encoding glutamate decarboxylase
De Biase, Daniela; Simmaco, Maurizio; Sweeney, G; Barra, Donatella; Bossa, Francesco; John, Ra - 01a Articolo in rivista
rivista: BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY (Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331) pp. 139-142 - issn: 0885-4513 - wos: WOS:A1993MB80100003 (7) - scopus: 2-s2.0-84981994611 (9)

11573/190511 - 1993 - Immunohistochemical localization of neutral protease inhibitors in the hamster skeletal muscle.
De Santis, Elena; Nori, S. L.; Toesca, A; Pompili, Elena; De Biase, Daniela; Ippoliti, F; De Renzis, G; Fumagalli, Lorenzo - 04d Abstract in atti di convegno
congresso: XIth International Symposium on Morphological Sciences (Barcelona (Spain))

11573/197207 - 1993 - Immunohistochemical localization of two proteinase inhibitors in normal skeletal muscle fibres.
Fumagalli, Lorenzo; Nori, S. L.; Toesca, A; De Biase, Daniela; Pompili, Elena; De Santis, Elena; De Renzis, G. - 04d Abstract in atti di convegno
rivista: EUROPEAN JOURNAL OF NEUROSCIENCE (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. - - issn: 0953-816X - wos: (0) - scopus: (0)
congresso: 16th Annual Meeting of the European Neuroscience Association (Madrid (Spain))

11573/50384 - 1992 - Protein structure of pig liver 4-aminobutyrate aminotransferase and comparison with cDNA deduced sequence.
De Biase, Daniela; Maras, Bruno; Bossa, Francesco; Barra, Donatella; John, Ra - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF BIOCHEMISTRY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 351-357 - issn: 0014-2956 - wos: WOS:A1992JM09700019 (22) - scopus: 2-s2.0-0026730877 (20)

11573/134129 - 1991 - The mechanism of inactivation of ornithine and GABA-transaminases by GABA analogs
De Biase, Daniela; Barra, Donatella; Bolton, J. B.; Bossa, Francesco; John, R. A. - 02a Capitolo o Articolo
libro: Enzymes Dependent on Pyrodoxal phosphate and Other Carbonyl Compounds as Cofactors - ()

11573/50385 - 1991 - CHEMISTRY OF THE INACTIVATION OF 4-AMINOBUTYRATE AMINOTRANSFERASE BY THE ANTIEPILEPTIC DRUG VIGABATRIN
De Biase, Daniela; Barra, Donatella; Bossa, Francesco; P., Pucci; John, Ra - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 20056-20061 - issn: 0021-9258 - wos: WOS:A1991GM03900031 (47) - scopus: 2-s2.0-0025723984 (56)

11573/49339 - 1991 - A chromophore in glutamate decarboxylase has been wrongly identified as PQQ
De Biase, Daniela; Maras, Bruno; John, Ra - 01a Articolo in rivista
rivista: FEBS LETTERS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 120-122 - issn: 0014-5793 - wos: WOS:A1991EY74000029 (14) - scopus: 2-s2.0-0026007616 (12)

11573/50386 - 1991 - MECHANISM OF INACTIVATION AND IDENTIFICATION OF SITES OF MODIFICATION OF ORNITHINE AMINOTRANSFERASE BY 4-AMINOHEX-5-YNOATE
De Biase, Daniela; Simmaco, Maurizio; Barra, Donatella; Bossa, Francesco; Michael, Hewlins; John, Ra - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 2239-2246 - issn: 0006-2960 - wos: WOS:A1991EZ60200029 (11) - scopus: 2-s2.0-0026101156 (8)

11573/134127 - 1991 - Evidence that glutamate decarboxylase and ornithine aminotransferase are not quinoproteins.
John, R. A.; De Biase, Daniela; Maras, Bruno - 02a Capitolo o Articolo
libro: Enzymes Dependent on Pyridoxal phosphate and Other Carbonyl Compounds as Cofactors. - ()

11573/49340 - 1990 - Crystallization and preliminary X-ray analysis of gamma-aminobutyric acid transaminase
Markovic Housley, Z.; Schirmer, T.; Fol, B.; Jansonius, J. N.; De Biase, Daniela; John, R. A. - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, -London; New York: Academic Press.) pp. 821-823 - issn: 0022-2836 - wos: WOS:A1990DV75000006 (2) - scopus: 2-s2.0-0025091665 (6)

11573/49341 - 1990 - Automated amino acid analysis using pre-column derivatization with dansyl chloride and reversed-phase high performance liquid chromatography
Simmaco, Maurizio; De Biase, Daniela; Barra, Donatella; Bossa, Francesco - 01a Articolo in rivista
rivista: JOURNAL OF CHROMATOGRAPHY (Amsterdam : Elsevier) pp. 129-138 - issn: 0021-9673 - wos: WOS:A1990CZ69600010 (43) - scopus: 2-s2.0-0025235392 (50)

11573/49342 - 1990 - Purification and characterization of bioactive peptides from the skin extract of Rana esculenta.
Simmaco, Maurizio; De Biase, Daniela; Severini, C; Aita, M; Falconieri Erspamer, G; Barra, Donatella; Bossa, Francesco - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 318-323 - issn: 0006-3002 - wos: WOS:A1990CW64300017 (58) - scopus: 2-s2.0-0025095549 (57)

11573/49550 - 1990 - Six novel tachykinin- and bombesin-related peptides from the skin of the australian frog Pseudophryne guntheri.
Simmaco, Maurizio; Severini, C; De Biase, Daniela; Barra, Donatella; Bossa, Francesco; Roberts, Jd; Melchiorri, P; Erspamer, V. - 01a Articolo in rivista
rivista: PEPTIDES (Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680) pp. 299-304 - issn: 0196-9781 - wos: WOS:A1990CY61100018 (37) - scopus: 2-s2.0-0025253089 (38)

11573/49551 - 1989 - Stoichiometry and stability of the adduct formed between human 4-aminobutyrate aminotransferase and 4-aminohex-5-enoate: sequence of a labelled peptide.
De Biase, Daniela; Bolton, Jb; Barra, Donatella; Bossa, Francesco; John, Ra - 01a Articolo in rivista
rivista: BIOCHIMIE (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 491-495 - issn: 0300-9084 - wos: WOS:A1989U884100011 (9) - scopus: 2-s2.0-0024311568 (8)

11573/243643 - 1988 - In situ treatment of proteins prior to sequence analysis
Schinina', Maria Eugenia; De Biase, Daniela; Bossa, Francesco; Barra, Donatella - 01a Articolo in rivista
rivista: JOURNAL OF PROTEIN CHEMISTRY (Plenum Press:Book Customer Service, 233 Spring Street:New York, NY 10013:(212)620-8471, (212)620-8000, EMAIL: info@plenum.com, INTERNET: http://www.plenum.com, Fax: (212)807-1047) pp. 284-286 - issn: 0277-8033 - wos: WOS:A1988P167300088 (9) - scopus: (0)

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma