Phd in MOLECULAR MEDICINE

email: claudio.talora@uniroma1.it
phone: +390649255674
building: B
room: 407

Present Position
Full Professor , Medical Laboratory Science MED/46

Education and training

Since 2020 Full Professor of Medical Laboratory Science MED/46 at the Department of Molecular Medicine University of Rome La Sapienza
2007-2020 Associate Professor of Pathology at the Department of Molecular Medicine University of Rome La Sapienza
2002-2007 Post-Doc; Department of Experimental Medicine, La Sapienza University of Rome, Rome, IT, Project: T cells development and transformation/keratinocytes growth and transformation.
1999-2002 Postdoctoral Fellow; Department of Dermatology, CBRC-MGH and Harvard Medical School
1997-1999 PhD student; Dep. of Genetic and Molecular Biology, La Sapienza University of Rome, Rome, IT
1996-1997 Research Associate Fellow; Regina Elena Cancer Institute, Rome, IT
1995 -La Sapienza University of Rome, Rome, Italy Laurea 1995 Biology

Major Research Interests
-molecular and cellular biology of cancer
-keratinocyte growth and differentiation control


Selected Publications (5 last years)

1. Functional cooperation between ASK1 and p21Waf1/Cip1 in the balance of cell-cycle arrest, cell death and tumorigenesis of stressed keratinocytes.
De Blasio C, Verma N, Moretti M, Cialfi S, Zonfrilli A, Franchitto M, Truglio F, De Smaele E, Ichijo H, Naguro I, Screpanti I, Talora C. Cell Death Discov. 2021 Apr 12;7(1):75.

2. Hypotonic, Acidic Oxidizing Solution Containing Hypochlorous Acid (HClO) as a Potential Treatment of Hailey-Hailey Disease.
Cialfi S, Calabro S, Franchitto M, Zonfrilli A, Screpanti I, Talora C. Molecules. 2019 Dec 4;24(24):4427.

3. PLK1 targets NOTCH1 during DNA damage and mitotic progression.
De Blasio C, Zonfrilli A, Franchitto M, Mariano G, Cialfi S, Verma N, Checquolo S, Bellavia D, Palermo R, Benelli D, Screpanti I, Talora C. J Biol Chem. 2019 Nov 22;294(47):17941-17950.

4.Kras/ADAM17-Dependent Jag1-ICD Reverse Signaling Sustains Colorectal Cancer Progression and Chemoresistance.
Pelullo M, Nardozza F, Zema S, Quaranta R, Nicoletti C, Besharat ZM, Felli MP, Cerbelli B, d'Amati G, Palermo R, Capalbo C, Talora C, Di Marcotullio L, Giannini G, Checquolo S, Screpanti I, Bellavia D. Cancer Res. 2019 Nov 1;79(21):5575-5586.

5.DNA Damage Stress: Cui Prodest?
Verma N, Franchitto M, Zonfrilli A, Cialfi S, Palermo R, Talora C. Int J Mol Sci. 2019 Mar 1;20(5):1073.