CARISSIMI Claudia
Dipartimento di Medicina Molecolare
Università degli Studi di Roma "La Sapienza"
claudia.carissimi@uniroma1.it
Titoli di studio
- Laurea SCIENZE BIOLOGICHE (vecchio ordinamento)- Università degli Studi di ROMA "La Sapienza"
- Dottore di ricerca in Genetica e biologia molecolare- Università degli Studi di ROMA "La Sapienza" -
Posizione
Ricercatore universitario a t.d. tipo B (SSD BIO-13)- Università degli Studi di ROMA "La Sapienza"- Dip. MEDICINA MOLECOLARE-Facoltà di Medicina e Farmacia
Attività didattica
Corso di laurea magistrale in Medicina e Chirurgia (corso B):
-Insegnamento: Biologia e Genetica (5 cfu, 60 ore, SSD: BIO/13)
-Coordinamento del corso integrato di Biologia e Genetica (CFU: 13, SSD: BIO/13)
-Membro della Commissione Tecnica di Programmazione didattico-pedagogica (CTP)
Elenco dei prodotti della ricerca:
Ilaria Laudadio, Alex Bastianelli, Valerio Fulci, Claudia Carissimi, Eleonora Colantoni, Francesca Palone, Roberta Vitali, Elisa Lorefice, Salvatore Cucchiara, Anna Negroni, Laura Stronati (2022). ZNF281 Promotes Colon Fibroblast Activation in TGFß1-Induced Gut Fibrosis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 23, ISSN: 1422-0067, doi: 10.3390/ijms231810261
Vitali, Roberta, Palone, Francesca, Armuzzi, Alessandro, Fulci, Valerio, Negroni, Anna, Carissimi, Claudia, Cucchiara, Salvatore, Stronati, Laura (2022). Proteomic analysis identifies three reliable biomarkers of intestinal inflammation in the stools of patients with Inflammatory Bowel Disease. JOURNAL OF CROHN'S AND COLITIS, ISSN: 1873-9946, doi: 10.1093/ecco-jcc/jjac110
Carissimi, Claudia, Laudadio, Ilaria, Lorefice, Elisa, Azzalin, Gianluca, De Paolis, Veronica, Fulci, Valerio (2021). Bisulfite miRNA-seq reveals widespread CpG and non-CpG 5-(hydroxy)methyl-Cytosine in human microRNAs. RNA BIOLOGY, ISSN: 1547-6286, doi: 10.1080/15476286.2021.1927423
De Paolis V., Lorefice E., Orecchini E., Carissimi C., Laudadio I., Fulci V. (2021). Epitranscriptomics: a new layer of microRNA regulation in cancer. CANCERS, vol. 13, ISSN: 2072-6694, doi: 10.3390/cancers13133372
Fulci, V, Carissimi, C, Laudadio, I (2021). COVID-19 and preparing for future ecological crises: hopes from metagenomics in facing current and future viral pandemic challenges. OMICS, vol. 25, p. 336-341, ISSN: 1536-2310, doi: 10.1089/omi.2021.0058
Putignani, Lorenza, Oliva, Salvatore, Isoldi, Sara, Del Chierico, Federica, Carissimi, Claudia, Laudadio, Ilaria, Cucchiara, Salvatore, Stronati, Laura (2021). Fecal and mucosal microbiota profiling in pediatric inflammatory bowel diseases. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, vol. Publish Ahead of Print, ISSN: 0954-691X, doi: 10.1097/MEG.0000000000002050
Valerio Fulci, Laura Stronati, Salvatore Cucchiara, Ilaria Laudadio, Claudia Carissimi (2021). Emerging roles of gut virome in pediatric diseases. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 22, ISSN: 1422-0067, doi: 10.3390/ijms22084127
Laudadio I, Cesi V, Carissimi C (2020). Metagenomics in Italy and Europe: three actionable challenges/prospects in 2020. OMICS, vol. 24, p. 122-123, ISSN: 1557-8100, doi: 10.1089/omi.2020.0006
Salvatore Oliva, Ilaria Laudadio, Valerio Fulci, ROSSETTI, DANILO, Sara Isoldi, Laura Stronati, Claudia Carissimi (2020). SERPINB12 as a possible marker of steroid dependency in children with eosinophilic esophagitis: a pilot study. DIGESTIVE AND LIVER DISEASE, vol. 52, p. 158-163, ISSN: 1590-8658, doi: 10.1016/j.dld.2019.08.018
Claudia Carissimi, Ilaria Laudadio, Francesca Palone, Valerio Fulci, Vincenzo Cesi, Cardona Francesco, Chiara Alfonsi, Salvatore Cucchiara, Sara Isoldi, Laura Stronati (2019). Functional analysis of gut microbiota and immunoinflammation in children with autism spectrum disorders. DIGESTIVE AND LIVER DISEASE, vol. 51, p. 1366-1374, ISSN: 1590-8658, doi: 10.1016/j.dld.2019.06.006
Ilaria Laudadio, Valerio Fulci, Laura Stronati, Claudia Carissimi (2019). Next generation metagenomics: methodological challenges and opportunities. OMICS, vol. 23, p. 327-333, ISSN: 1557-8100, doi: 10.1089/omi.2019.0073
Laudadio, Ilaria, Carissimi, Claudia, Fulci, Valerio (2019). How RNAi machinery enters the world of telomerase. CELL CYCLE, vol. 18, p. 1056-1067, ISSN: 1538-4101, doi: 10.1080/15384101.2019.1609834
Laudadio, Ilaria, Orso, Francesca, Azzalin, Gianluca, Calabrò, Carlo, Berardinelli, Francesco, Coluzzi, Elisa, Gioiosa, Silvia, Taverna, Daniela, Sgura, Antonella, Carissimi, Claudia, Fulci, Valerio (2019). AGO2 promotes telomerase activity and interaction between the telomerase components TERT and TERC. EMBO REPORTS, vol. 20, ISSN: 1469-3178, doi: 10.15252/embr.201845969
Salvatore Oliva, Claudia Carissimi, Ilaria Laudadio, Valerio Fulci, Danilo Rossetti, Sara Isoldi, Salvatore Cucchiara, Laura Stronati (2019). Sa1295 – Serpinb12 As a Possible Marker of Steroid Dependency in Children with Eosinophilic Esophagitis: A Pilot Study. GASTROENTEROLOGY, vol. 156, p. S-309, ISSN: 0837-0036, doi: 10.1016/S0016-5085(19)37593-6
Ilaria Laudadio, Sara Formichetti, Silvia Gioiosa, Filippos Klironomos, Nikolaus Rajewsky, GiuseppeMacino, Claudia Carissimi, Valerio Fulci (2018). Characterization of transcription termination associated-RNAs (TTSa-RNAs): new insights into their biogenesis, tailing and expression in primary tumors. INTERNATIONAL JOURNAL OF GENOMICS, vol. 2018, ISSN: 2314-4378, doi: 10.1155/2018/1243858
Ilaria Laudadio, Valerio Fulci, Francesca Palone, Laura Stronati, Salvatore Cucchiara, Claudia Carissimi (2018). Quantitative assessment of shotgun metagenomics and 16S rDNA amplicon sequencing in the study of Human Gut Microbiome. OMICS, vol. 22, p. 248-254, ISSN: 1557-8100, doi: 10.1089/omi.2018.0013
CARISSIMI, Claudia, COLOMBO, TERESA, AZZALIN, Gianluca, CIPOLLETTA, EMANUELA, LAUDADIO, ILARIA, MACINO, Giuseppe, FULCI, Valerio (2016). Comprehensive RNA dataset of AGO2 associated RNAs in Jurkat cells following miR-21 over-expression. DATA IN BRIEF, vol. 7, p. 604-606, ISSN: 2352-3409, doi: 10.1016/j.dib.2016.02.041
GIOIOSA, SILVIA, VERDUCI, LORENA, AZZALIN, Gianluca, CARISSIMI, Claudia, FULCI, Valerio, MACINO, Giuseppe (2016). Microarray dataset of Jurkat cells following miR-93 over-expression. DATA IN BRIEF, vol. 8, p. 575-8-578, ISSN: 2352-3409, doi: 10.1016/j.dib.2016.06.001
CARISSIMI, Claudia, LAUDADIO, ILARIA, CIPOLLETTA, EMANUELA, GIOIOSA, SILVIA, Mihailovich M, Bonaldi T, MACINO, Giuseppe, FULCI, Valerio (2015). ARGONAUTE2 cooperates with SWI/SNF complex to determine nucleosome occupancy at human Transcription Start Sites.. NUCLEIC ACIDS RESEARCH, vol. 43, p. 1498-1512, ISSN: 1362-4962, doi: 10.1093/nar/gku1387
Krell, J, Stebbing, J, Frampton, Ae, CARISSIMI, Claudia, Harding, V, De Giorgio, A, FULCI, Valerio, MACINO, Giuseppe, COLOMBO, TERESA, Castellano, L. (2015). The role of TP53 in miRNA loading onto AGO2 and in remodelling the miRNA-mRNA interaction network. In: Spring Meeting for Clinician Scientists in Training 2015. THE LANCET, vol. 385 Suppl 1, p. S15, ISSN: 0140-6736, ..., doi: 10.1016/S0140-6736(15)60330-0
Krell, Jonathan, Stebbing, Justin, CARISSIMI, Claudia, Dabrowska, Aleksandra, de Giorgio, Alexander, Frampton, Adam Enver, Harding, Victoria, FULCI, Valerio, MACINO, Giuseppe, Colombo, Teresa, Castellano, Leandro (2015). TP53 regulates miRNA association with AGO2 to remodel the miRNA-mRNA interaction network. GENOME RESEARCH, p. gr.191759.115-..., ISSN: 1088-9051, doi: 10.1101/gr.191759.115
VERDUCI, LORENA, AZZALIN, Gianluca, GIOIOSA, SILVIA, CARISSIMI, Claudia, LAUDADIO, ILARIA, FULCI, Valerio, MACINO, Giuseppe (2015). microRNA-181a enhances cell proliferation in Acute Lymphoblastic Leukemia by targeting EGR1. LEUKEMIA RESEARCH, ISSN: 0145-2126, doi: 10.1016/j.leukres.2015.01.010
CARISSIMI, Claudia, CARUCCI, Nicoletta, COLOMBO, TERESA, PICONESE, SILVIA, AZZALIN, Gianluca, CIPOLLETTA, EMANUELA, CITARELLA, Franca, BARNABA, Vincenzo, MACINO, Giuseppe, FULCI, Valerio (2014). miR-21 is a negative modulator of T-cell activation. BIOCHIMIE, p. ..., ISSN: 0300-9084, doi: 10.1016/j.biochi.2014.09.021
CARISSIMI, Claudia, FULCI, Valerio, NASI, SERGIO, Montalban, Enrica, Mattugini, Nicola, Ciarapica, Roberta, Provenzano, Claudia, SAVINO, MAURO, SCAGNOLI, FIORELLA, Prosperini, Gianluca, Matrone, Carmela, Calissano, Pietro (2014). MiR-21 is an Ngf-modulated MicroRNA That supports Ngf signaling and regulates neuronal degeneration in PC12 cells. NEUROMOLECULAR MEDICINE, vol. 16, p. 415-430, ISSN: 1535-1084, doi: 10.1007/s12017-014-8292-z
CURTALE G, CITARELLA, Franca, CARISSIMI, Claudia, GOLDONI M, CARUCCI N, FULCI, Valerio, FRANCESCHINI D, MELONI F, BARNABA, Vincenzo, MACINO, Giuseppe (2010). An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and AICD in T lymphocytes. BLOOD, vol. 115 (2), p. 265-273, ISSN: 0006-4971, doi: 10.1182/blood-2009-06-225987
Curtale, G., CITARELLA, Franca, CARISSIMI, Claudia, Carucci, N., FULCI, Valerio, Franceschini, D., Meloni, F., BARNABA, Vincenzo, MACINO, Giuseppe (2010). An Emerging Player in the Adaptive Immune Response: MicroRNA-146a is a modulator of IL-2 expression and AICD in T lymphocytes. In: 44th Annual Scientific Meeting of the European Society for Clinical Investigation, Bari, Italy, 24-27 February 2010. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, vol. 40, p. 52, Wiley Online Library, ISSN: 0014-2972, Bari, Italy,, 24-27 February 2010
CARISSIMI, Claudia, FULCI, Valerio, MACINO, Giuseppe (2009). MicroRNAs: Novel regulators of immunity.. AUTOIMMUNITY REVIEWS, vol. 8(6), p. 520-524, ISSN: 1568-9972, doi: 10.1016/j.autrev.2009.01.008
GABANELLA F, BUTCHBACH ME, SAIEVA L, CARISSIMI, Claudia, BURGHES AH, PELLIZZONI L. (2007). Ribonucleoprotein Assembly Defects Correlate with Spinal Muscular Atrophy Severity and Preferentially Affect a Subset of Spliceosomal snRNPs. PLOS ONE, vol. 2(9), ISSN: 1932-6203
CARISSIMI, Claudia, SAIEVA L, BACCON J, CHIARELLA P, MAIOLICA A, SAWYER A, RAPPSILBER J, PELLIZZONI L. (2006). Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assembly. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 281(12), p. 8126-8134, ISSN: 0021-9258, doi: 10.1093/hmg/ddi390
CARISSIMI, Claudia, SAIEVA L, GABANELLA F, PELLIZZONI L. (2006). Gemin8 is required for the architecture and function of the survival motor neuron complex.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 281(48), p. 37009-37016, ISSN: 0021-9258
CARISSIMI, Claudia, BACCON J, STRACCIA M, CHIARELLA P, MAIOLICA A, SAWYER A, RAPPSILBER J, PELLIZZONI L. (2005). Unrip is a component of SMN complexes active in snRNP assembly.. FEBS LETTERS, vol. 579(11), p. 2348-2354, ISSN: 0014-5793
GABANELLA F, CARISSIMI, Claudia, USIELLO A, PELLIZZONI L. (2005). The activity of the spinal muscular atrophy protein is regulated during development and cellular differentiation.. HUMAN MOLECULAR GENETICS, vol. 14(23), p. 3629-3642, ISSN: 0964-6906
CARDINALI B, CARISSIMI, Claudia, GRAVINA P, PIERANDREI AMALDI P. (2003). La protein is associated with terminal oligopyrimidine mRNAs in actively translating polysomes.. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 278(37), p. 35145-35151, ISSN: 0021-9258