CECILIA BATTISTELLI

Associate professor


email: cecilia.battistelli@uniroma1.it
phone: +390649918236
building: 5 clinica Medica 2 piano Policlinico Umberto I
room: 217

CECILIA BATTISTELLI
Curriculum Vitae
Place: Roma
Date: 17/03/2022

Part I – General Information
Full Name Cecilia Battistelli
Citizenship Italian
Work Address Viale regina Elena 324, 00161, Roma
Phone Number +39 0649918236
E-mail cecilia.battistelli@uniroma1.it
Spoken Languages Italian (mother tongue), English, French

Part II – Education
University graduation 2007 Sapienza University of Rome Biological Sciences (Degree), full marks and honors
Thesis title: Analysis of the regulation of microRNAs biosynthesis.
Tutor: Prof. Irene Bozzoni, University of Rome "Sapienza"
University graduation 2008 Sapienza University of Rome Biology (LS: Genetics and Molecular Biology), full marks and honors
Thesis title: Mechanisms regulating p57kip2 expression during muscle differentiation: role of DNA methylation.
Tutors: Prof. Gabriella Augusti Tocco, University of Rome "Sapienza" and Prof. Rossella Maione, University of Rome "Sapienza”
Italian Biological Licensure (ESAME DI STATO) 2011 Sapienza University of Rome
PhD 2012 Sapienza University of Rome PhD in Human Biology and Genetics
Thesis title: MyoD regulates p57kip2 expression through a long-range chromatin interaction.
Tutor: Prof. Rossella Maione, University of Rome “Sapienza”

Part III – Appointments
IIIA – Academic Appointments
15/07/2021 14/07/2024 Sapienza University of Rome Ricercatore a tempo determinato (RTD) tipo B BIO13
01/05/2018 30/04/2021 Sapienza University of Rome Ricercatore a tempo determinato (RTD) tipo A BIO13
18/09/2018 18/09/2027 Abilitazione Scientifica Nazionale 05/F1 II FASCIA
1/1/2012 30/04/2018 Sapienza University of Rome Research Fellowship (PI: Prof. Marco Tripodi)


IIIB – Other Appointments
1/4/2017 31/05/2017 Pasteur Institute Italy- Cenci Bolognetti Foundation Research Fellowship (PI: Prof. Marco Tripodi)
1/1/2013 28/02/2013 Pasteur Institute Italy- Cenci Bolognetti Foundation Research Fellowship (PI: Prof. Marco Tripodi)
1/11/2011 31/12/2011 Pasteur Institute Italy- Cenci Bolognetti Foundation Research Fellowship (PI: Prof. Rossella Maione)

Part IV – Teaching experience
2018/2019 Sapienza University of Rome Medicina e Chirurgia (canale C)
Biologia e Genetica I, modulo di Biologia Cellulare (2cfu)
2018/2022 Sapienza University of Rome Tecniche di Fisiopatologia Cardio-circolatoria e Perfusione Cardiovascolare
Basi cellulari e molecolari della vita, modulo di Biologia Applicata (2cfu)
2018/2021 Sapienza University of Rome Tecniche Ortopediche
Scienze Biomediche I, modulo di Biologia (2cfu)
2019/2022 Sapienza University of Rome Ostetricia
Basi molecolari e cellulari della vita, modulo di Biologia applicata (2cfu)

Other Teaching experiences
2013-2022 Partecipation to ADE/lessons:
Laurea Magistrale “A” in Medicina e Chirurgia e del corso di Laurea Magistrale in Biotecnologie Mediche (Prof. M. Tripodi)
Corso di Laurea Magistrale a ciclo unico in Medicina e Chirurgia (Prof. R. Strippoli)
Corso di Laurea Magistrale “C” e del corso di Laurea Magistrale “F” in Medicina e Chirurgia (Prof.ssa F. Citarella)

ASN Simulation
Value Description Threshold
24 Numero articoli ultimi 5 anni 8 SECONDA FASCIA
977 Numero citazioni ultimi 10 anni 307 SECONDA FASCIA
16 H index ultimi 10 anni 8 SECONDA FASCIA
33 Numero articoli ultimi 10 anni 23 PRIMA FASCIA
977 Numero citazioni ultimi 15 anni 770 PRIMA FASCIA
16 H index ultimi 15 anni 15 PRIMA FASCIA
33 Numero articoli ultimi 10 anni 31 COMMISSARIO
977 Numero citazioni ultimi 15 anni 1163 COMMISSARIO
16 H index ultimi 15 anni 19 COMMISSARIO

Supervision of thesis
2017/2018 Sapienza University of Rome, Facoltà di farmacia e Medicina, Corso di laurea in Biotecnologie (1 student)
Thesis title: “Ruolo dello stretching meccanico nell’induzione della transizione epitelio-mesenchimale (EMT) nelle cellule peritoneali”
2019/2020 Erasmus Degree Project
Sapienza University of Rome and Universitat de Barcelona (Spain) (1 student)
Thesis title: “Exosome-mediated intercellular communication, the role of cellular RNA-binding proteins”
2020/2022 Sapienza University of Rome, Facoltà di farmacia e Medicina, Corso di laurea in Biotecnologie mediche (3 students)
Thesis title: “Studio del ruolo della modifica m6A sui microRNA espressi in cellule di epatocarcinoma”
2 ongoing thesis projects
2020/2021 Sapienza University of Rome, Facoltà di farmacia e Medicina, Corso di laurea in Farmacia (1 student)
Thesis title: “Studio degli effetti dell’inibizione della “Methyltransferase-like 3” in epatocarcinoma”.
2022 Erasmus Plus Project
Sapienza University of Rome and Istanbul Medeniyet University (2 students)

Participation to Doctorate programmes
Sept.2019/today Sapienza University of Rome PhD program in Human Biology and Medical Genetics

Supervision of national and international PhD thesis
2020 Universität des Saarlandes (Germany) Thesis title: Design and synthesis of novel ligands for serotonin (5-HT6) receptor and inhibitors of ABCB1 efflux pump
2021 Sapienza University of Rome 1 PhD Student (First year)

Part V – Society memberberships
Year Title
2015-2019 ABCD (Associazione di Biologia Cellulare e del Differenziamento)
2018-today Epigenetics Society
2013-2015 TEMTIA (The EMT International Association)
2020-today EVIta (Extracellular Vesicle Italy)

Oral Presentations
7-8/6/2021 INVITED SPEAKER III international AICC Exosome Meeting “Cell to cell delivery in cancer and therapy: a matter of carriers and messages” Virtual Event
6-8/11/2019 1st EVIta Symposium, Palermo
22-24/11/2018 ABCD Meeting: “Signal Transduction in Cancer”, Turin
23/11/2016 INVITED SPEAKER at the Bambino Gesù Children’s Hospital (Rome).
Seminar title: The Snail repressor recruits EZH2 to specific genomic sites through the enrolment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition
20-23/9/2016 – XIV FISV Congress – Rome 
30/9-1/10 2016 – XVII AIBG Congress – Cagliari
17-19/9/2015 – ABCD meeting – Bologna
7/9/2015 – RNA day 2015, the multi-faceted non coding RNA landscape – Rome
24-25-26-27/9/2014 – Congress FISV 2014- Pisa
12-13/9/2013 – Conference “RNA day 2013, the centrality of non coding RNA in gene-regulation”- Roma
12-13-14/10/2012 – 9° annual meeting IIM- Acaya, Lecce.
24-25-26/5/2012 – “Frontiers in molecular biology” SIBBM congress – Palermo.
4-5-6/6/2009 – “Frontiers in molecular biology” SIBBM Congress – Napoli.

Awards and Honors
Year Title
2019 EVIta (Extracellular Vesicle Italy) award (best oral presentation)
2018 AIRC award at the AIBG (Associazione Italiana Biologia e Genetica) Congress (young investigator award)
2013 TEMTIA (The EMT International Association) award (young investigator award)
2012 IIM (Italian Institute of Myology) award (best oral presentation)
2012 SIBBM (Società Italiana Biofisica Biologia Molecolare) award (best oral presentation)
2011 EMBO award (young investigator award)
2010 Collegio Ghislieri award (young investigator award)

Editorial activity
2016-2017
2017-2018 Academic Editor “Mediators of Inflammation”
Academic Editor “Frontiers in Pharmacology”
2019-2020 Academic Editor “Frontiers in Pharmacology”
2020 Academic Editor “Biomedicine”
2020 Review Editor for the Cellular Biochemistry section of “Frontiers in Cell and Developmental Biology” and of “Frontiers in Molecular Biosciences”

Peer Review activity
Peer review activity for the following journals:
Cell death and Differentiation, Oncogene, Cancers, Sensors, Molecules, Molecular Cancer, International Journal of Molecular Sciences, Cancer Medicine, Experimental and Molecular Pathology, Cellular Physiology and Biochemistry, Clinics and Research in Hepatology and Gastroenterology, Cells, Cell communication and Signalling, International Journal of Cancer, Cell Death and Disease, Gene, Genes, Pharmaceuticals, Oxidative Medicine and Cellular longevity, Cancer Gene Therapy, Frontiers in Cell and Developmental Biology, Cancer Cell International.

Part VI – Funding Information [grants as PI-principal investigator or I-investigator]

2008 “Differenziamento miogenico e neuronale: fattori di regolazione”. (I) Ricerche UNIVERSITARIE (ex ricerche di ATENEO) codice C26A082MNW.
2009-2011 Interplay between myogenic factors and cell cycle control. (I) Istituto Pasteur – Fondazione Cenci Bolognetti
2012-2014 Transcriptional regulation through long-range chromatin interactions in muscle cells: the CDKN1C-KCNQ1 locus. (I) Istituto Pasteur – Fondazione Cenci Bolognetti
2014-2016 Dissecting HNF4and Snail functions in hepatocyte reprogramming: role in liver cancer and fibrosis (I) AIRC Investigator Grant n.IG14114
2017-2019 Developing ncRNAs-based strategies to counteract epithelial tumour progression and metastasis (I) AIRC Investigator Grant n.IG18843
2019 Molecular strategies to antagonize the epithelial to mesenchymal transition (EMT) by interfering with the function of the lncRNA Hotair (I) Ricerche UNIVERSITARIE
(ex ricerche di ATENEO) codice RM11916B6A80C2CF
2018 Study of tissue environmental cues inactivating the master regulator of hepatocyte differentiation, Hepatocyte Nuclear Factor 4, in liver diseases (I) Ricerche
UNIVERSITARIE (ex ricerche di ATENEO) codice RM1181643646188C
2021 Deciphering the role of m6A on HOTAIR function and EV-compartmentalization (PI) SEED PNR- Finanziamento di progetti di ricerca su temi di interesse trasversale
per il PNR

Part VII – Research Activities
Keywords
Transcriptional factors
Cell plasticity
Chromatin
ncRNAs
Cell differentiation
Tumorigenesis
Epithelial-to-mesenchymal transition
Epigenetics
Brief Description
I am interested in molecular mechanisms controlling cell plasticity. In particular I focused my investigation in mechanisms controlling cell differentiation, epithelial-to-mesenchymal transition and tumour onset and dissemination. My collaborators and I elucidated the role of MyoD in the control of p57 (a cyclin-dependent kinase inhibitor) during muscle differentiation through the direct binding to the chromatin, and of CTCF in the reorganization of chromatin structure in the same phenomenon. In three recent studies, I projected, developed and then elucidated with my team members the role and regulation of a lncRNA, HOTAIR, in the progression of epithelial-to-mesenchymal transition. Specifically, I found that this lncRNA binds to the chromatin, together with the transcriptional factor Snail, in order to recruit chromatin modifiers on the promoters of epithelial genes. Then I focused on its transcriptional regulation, mainly mediated by another transcriptional factor, HNF4a, that binds to its promoter and enhancer and modifies a higher-order chromatin structure promoting HOTAIR transcription. More recently I designed a strategy to counteract HOTAIR function in epithelial-to-mesenchymal transition through an RNA-based approach counteracting HOTAIR-Snail interaction and chromatin modifications on the promoter regions of Snail-target epithelial genes.
I am presently involved in research projects related to the identification of RNA-binding proteins interacting with microRNAs and responsible for microRNAs loading inside extracellular vesicles, specifically into exosomes. In this scenario I am also investigating the role of epitranscriptomics in modulating microRNA-protein interaction both in epithelial-to-mesenchymal transition and during differentiation.
Moreover, I have been implicated in the development and biological application of different epigenetic drugs able to modulate gene expression both in epithelial-to-mesenchymal transition and in tumorigenesis. With respect to this aspect, I focused on the use different inhibitors of chromatin modifiers (DNA methyltransferases, Histone deacetylases, Polycomb repressive complex 2) in order to verify whether they could restore epithelial cell features (and epithelial genes expression rescue) without affecting transcription factor binding to the promoters of several epithelial genes.

Scientific network:
Dr. Chiara Agrati, Istituto Nazionale per le Malattie Infettive "L.Spallanzani", Rome (INMI)
Prof. Andres Ramos, University College of London
Prof. Antonello Mai, Sapienza University of Rome
Prof. Frank J. Gonzalez, Center for Cancer Research, National Cancer Institute, Bethesda
Dr. Rosaria Benedetti, Università degli Studi della Campania "Luigi Vanvitelli, Naples
Prof. Miguel A. Del Pozo, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid
Prof. Manuel Lopez-Cabrera, Centro De Biología Molecular Severo Ochoa, Madrid
Prof. Jadwiga Handzlik, Jagiellonian University, Kraków, Poland
Prof. Claus Jacob, Universität des Saarlandes, Saarbrücken, Germany
Dr. Daniela Trisciuoglio, Italian National Research Council, Rome (CNR)
Dr. Loredana Cifaldi, University of Rome Tor Vergata

Part VIII – Summary of Scientific Achievements (papers published from 2012 to 2022)
Product type Number Data Base
Papers [international] 38 Scopus
https://www.scopus.com/author/submit/profile.uri?authorId=55371458900
2012 2022
Papers [international] 40 Google Scholar
https://scholar.google.it/citations?user=RTOf_14AAAAJ&hl=it&authuser=1&oi=ao
2012 2022

Scopus* Google Scholar*
Total Impact factor 268.036 268.036
Impact factor per product 7.05 6.70
First name products 12 13
Last name products 3 4
Corresponding author products 4 5
Total Citations 968 1185
Average Citations per Product. 25.47 29.63
Hirsch (H) index 16 17
Normalized H index** 1.14 1.21

All data were updated on 17/03/2022
*IF 2021
**H index divided by the academic seniority.

Part IX – Publications:
1) MyoD regulates p57kip2 expression by interacting with a distant cis-element and modifying a higher order chromatin structure
Authors: A. Busanello*, C. Battistelli*, M. Carbone, C. Mostocotto and R. Maione
*First authors
Nucleic Acids Res.2012 Sep 1;40(17):8266-75. doi:10.1093/nar/gks619. Epub 2012 Jun 26.PMID: 22740650
Journal: Nucleic Acids Research; IF 2012: 8.278

2) Functional interplay between MyoD and CTCF in regulating long-range chromatin interactions during differentiation
Authors: C. Battistelli, A. Busanello and R. Maione
J Cell Sci. 2014 Sep 1;127(Pt 17):3757-67. doi: 10.1242/jcs.149427. Epub 2014 Jul 7. PMID: 25002401 Journal: Journal of Cell Science; IF 2014: 5.432

3) Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29
Authors: C. Cicchini, V. de Nonno, C. Battistelli, A. M. Cozzolino, M. De Santis Puzzonia, S. A. Ciafrè, C. Brocker, F. J. Gonzalez, L. Amicone, and M. Tripodi
Biochim Biophys Acta. 2015 Aug;1849(8):919-29. doi: 10.1016/j.bbagrm.2015.05.005. Epub 2015 May 21.
PMID: 26003733
Journal: Biochimica et Biophysica Acta - Gene Regulatory Mechanisms; IF 2015: 5.373

4) Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes
Authors: A. M. Cozzolino, V. Noce, C. Battistelli, A. Marchetti, G. Grassi, C. Cicchini, M. Tripodi, and L. Amicone
Stem Cells Int. 2016;2016:5481493. doi: 10.1155/2016/5481493. Epub 2016 Jan 12. PMID: 27057172 Journal: Stem Cells International; IF 2016: 3.540

5) Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis
Authors: R. Strippoli, R. Moreno-Vicente, C. Battistelli, C. Cicchini, V. Noce, L. Amicone, A. Marchetti, M. A. del Pozo, and M. Tripodi
Stem Cells Int. 2016;2016:3543678. doi: 10.1155/2016/3543678. Epub 2016 Jan 31. PMID: 26941801 Journal: Stem Cells International; IF 2016: 3.540

6) The RNA-Binding Protein SYNCRIP Is a Component of the Hepatocyte Exosomal Machinery Controlling MicroRNA Sorting
Authors: L. Santangelo, G. Giurato, C. Cicchini, C. Montaldo, C. Mancone, R. Tarallo, C. Battistelli, T. Alonzi, A. Weisz, and M. Tripodi
Cell Rep. 2016 Oct 11;17(3):799-808. doi: 10.1016/j.celrep.2016.09.031. PMID: 27732855
Journal: Cell Reports; IF 2016: 8.282

7) A cross-talk between DNA methylation and H3 lysine 9 dimethylation at the KvDMR1 region controls the induction of Cdkn1c in muscle cells
Authors: O. Andresini, A. Ciotti, M. N. Rossi, C. Battistelli, M. Carbone, and R. Maione
Epigenetics. 2016 Nov;11(11):791-803. doi: 10.1080/15592294.2016.1230576. Epub 2016 Sep 9. PMID: 27611768
Journal: Epigenetics; IF 2016: 4.394

8) Functional Roles and Therapeutic Applications of Exosomes in Hepatocellular Carcinoma
Authors: L. Santangelo, C. Battistelli, C. Montaldo, F. Citarella, R. Strippoli and C. Cicchini
Biomed Res Int. 2017;2017:2931813. doi: 10.1155/2017/2931813. Epub 2017 Feb 7. PMID: 28265569 Journal: BioMed Research International; IF 2017: 2.583

9) The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition
Authors: C. Battistelli, C. Cicchini, L. Santangelo, A. Tramontano, L. Grassi, F. J. Gonzalez, V. de Nonno, G. Grassi, L. Amicone and M. Tripodi
Oncogene. 2017 Feb 16;36(7):942-955. doi: 10.1038/onc.2016.260. Epub 2016 Jul 25. PMID: 27452518 Journal: Oncogene; IF 2017: 6.854

10) SMO inhibition modulates cellular plasticity and invasiveness in colorectal cancer
Authors: P. Magistri*, C. Battistelli*, R. Strippoli, N. Petrucciani, T. Pellinen, L. Rossi, L. Mangogna, P. Aurello, F. D’Angelo, M. Tripodi, G. Ramacciato and G. Nigri
*First authors
Front Pharmacol. 2018 Feb 2;8:956. doi: 10.3389/fphar.2017.00956. eCollection 2017. PMID: 29456503 Journal: Frontiers in Pharmacology; IF 2018: 3.831

11) Hepatitis C virus direct-acting antivirals therapy impacts on extracellular vesicles microRNAs content and on their immunomodulating properties
Authors: L. Santangelo, V. Bordoni, C. Montaldo, E. Cimini, A. Zingoni, C. Battistelli, G. D’Offizi, M. R. Capobianchi, A. Santoni, M. Tripodi and C. Agrati
Liver Int. 2018 Oct;38(10):1741-1750. doi: 10.1111/liv.13700. Epub 2018 Feb 24. PMID: 29359389
Journal: Liver International; IF 2018: 5.542

12) A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets
Authors: F. Hobor, A. Dallmann, N. J. Ball, C. Cicchini, C. Battistelli, R. W. Ogrodowicz, E. Christodoulou, S. R. Martin, A. Castello, M. Tripodi, I. A. Taylor and A. Ramos
Nat Commun. 2018 Feb 26;9(1):831. doi: 10.1038/s41467-018-03182-3. PMID: 29483512
Journal: Nature Communications; IF 2018: 11.878

13) HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal
Authors: L. Rossi*, C. Battistelli*, V. de Turris, V. Noce, C. Zwergel, S. Valente, A. Moioli, A. Manzione, M. Palladino, V. Bordoni, A. Domenici, P. Menè, A. Mai, M. Tripodi and R. Strippoli
*First authors
Sci Rep. 2018 May 31;8(1):8492. doi: 10.1038/s41598-018-26319-2. PMID: 29855565
Journal: Scientific Reports; IF 2018: 4.011

14) TGFβ impairs HNF1α functional activity in Epithelial-to-Mesenchymal Transition interfering with the recruitment of CBP/p300 acetyltransferases
Authors: F. Bisceglia*, C. Battistelli*, V. Noce, C. Montaldo, A. Zammataro, R. Strippoli, M. Tripodi, L. Amicone and A. Marchetti
*First authors
Front Pharmacol. 2019 Aug 30;10:942. doi: 10.3389/fphar.2019.00942. eCollection 2019. PMID: 31543815 Journal: Frontiers in Pharmacology; IF 2019: 4.225

15) Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells
Authors: G. Stazi*, C. Battistelli*, V. Piano, R. Mazzone, B. Marrocco, S. Marchese, S. M. Louie, C. Zwergel, L. Antonini, A. Patsilinakos, R. Ragno, M. Viviano, G. Sbardella, A. Ciogli, G. Fabrizi, R. Cirilli, R. Strippoli, A. Marchetti, M. Tripodi, D. K. Nomura, A. Mattevi, A. Mai and S. Valente
*First authors
Eur J Med Chem. 2019 Feb 1;163:722-735. doi: 10.1016/j.ejmech.2018.11.050. Epub 2018 Nov 28. PMID: 30576903
Journal: European Journal of Medicinal Chemistry; IF 2019: 5.572

16) The lncRNA HOTAIR transcription is controlled by HNF4α-induced chromatin topology modulation
Authors: C. Battistelli, G. Sabarese, L. Santangelo, C. Montaldo, F. J. Gonzalez, M. Tripodi and C. Cicchini
Cell Death Differ. 2019 May;26(5):890-901. doi: 10.1038/s41418-018-0170-z. Epub 2018 Aug 28. PMID: 30154449
Journal: Cell Death and Differentiation; IF 2019: 10.717

17) Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells
Authors: C. Zwergel, M. Schnekenburger, F. Sarno, C. Battistelli, M. C. Manara, G. Stazi, R. Mazzone, R. Fioravanti, C. Gros, F. Ausseil, C. Florean, A. Nebbioso, R. Strippoli, T. Ushijima, K. Scotlandi, M. Tripodi, P. B. Arimondo, L. Altucci, M. Diederich, A. Mai and S. Valente
Clin Epigenetics. 2019 May 6;11(1):68. doi: 10.1186/s13148-019-0663-8. PMID: 31060628
Journal: Clinical Epigenetics; IF 2019: 5.028

18) Caveolin1 and YAP drive mechanically-induced mesothelial to mesenchymal transition and fibrosis
Authors: R. Strippoli, P. Sandoval, R. Moreno-Vicente, L. Rossi, C. Battistelli, M. Terri, L. Pascual-Antón, M. Loureiro, F. Matteini, E. Calvo, J. A. Jiménez-Heffernan, M. J. Gómez, V. Jiménez-Jiménez, F. Sánchez-Cabo, J. Vázquez, M. Tripodi, M. López-Cabrera and M. Á. del Pozo
Cell Death Dis. 2020 Aug 3;11(8):647. doi: 10.1038/s41419-020-02822-1. PMID: 32811813
Journal: Cell Death and Disease; IF 2020: 6.304

19) The innovative potential of selenium-containing agents for fighting cancer and viral infections
Authors: W. Ali, R. Benedetti, J. Handzlik, C. Zwergel and C. Battistelli
Accepted manuscript (19/10/2020), in press, https://doi.org/10.1016/j.drudis.2020.10.014
Journal: Drug Discovery Today; IF 2020: 7.321

20) Design and functional validation of a mutant variant of the lncRNA HOTAIR to counteract Snail function in Epithelial-to-Mesenchymal Transition
Authors: C. Battistelli#, S. Garbo, V. Riccioni, C. Montaldo, L. Santangelo, A. Vandelli, R. Strippoli, G. G. Tartaglia, M. Tripodi# and C. Cicchini
#Corresponding authors
Accepted manuscript (27/10/2020), in press.
Journal: Cancer Research; IF 2020: 9.727

21) Spike-in SILAC proteomic approach reveals the vitronectin as an early molecular signature of liver fibrosis in hepatitis C infections with hepatic iron overload.
Authors: Montaldo C, Mattei S, Baiocchini A, Rotiroti N, Del Nonno F, Pucillo LP, Cozzolino AM, Battistelli C, Amicone L, Ippolito G, van Noort V, Conigliaro A, Alonzi T, Tripodi M, Mancone C.
Proteomics. 2014 May;14(9):1107-15. doi: 10.1002/pmic.201300422. PMID: 24616218
Journal: Proteomics; IF 2014 3.807

22) Poly(ADP-ribosyl)ation is required to modulate chromatin changes at c-MYC promoter during emergence from quiescence.
Authors: Mostocotto C, Carbone M, Battistelli C, Ciotti A, Amati P, Maione R.
PLoS One. 2014 Jul 21;9(7):e102575. doi: 10.1371/journal.pone.0102575. eCollection 2014. PMID: 25047032
Journal: Plos One; IF 2014 3.234

23) SETDB1 is a new promising target in HCC therapy.
Authors: Cicchini C, Battistelli C, Tripodi M.
Chin Clin Oncol. 2016 Dec;5(6):73. doi: 10.21037/cco.2016.05.04. Epub 2016 Jun 3. PMID: 27334461
Journal: Chin Clin Oncol.; IF 2016 n.d.

24) Targeting of polycombs to DNA in EMT.
Authors: Battistelli C, Tripodi M, Cicchini C.
Oncotarget. 2017 Aug 12;8(35):57936-57937. doi: 10.18632/oncotarget.20211. eCollection 2017 Aug 29.
PMID: 28938527
Journal: Oncotarget; IF 2017 n.d.

25) Promotion of proliferation and metastasis of hepatocellular carcinoma by LncRNA00673 based on the targeted-regulation of notch signaling pathway
Authors: P Magistri 1, C Battistelli, G Assirati, F Mereu, G Tarantino, G P Guerrini, R Ballarin, F Di Benedetto
Eur Rev Med Pharmacol Sci. 2017 Oct;21(19):4261-4262. PMID: 29077173
Journal: Eur Rev Med Pharmacol Sci. IF 2017: 2.387

26) The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter.
Authors: Fazi B, Garbo S, Toschi N, Mangiola A, Lombari M, Sicari D, Battistelli C, Galardi S, Michienzi A, Trevisi G, Harari-Steinfeld R, Cicchini C, Ciafrè SA.
Oncotarget. 2018 Feb 14;9(21):15512-15525. doi: 10.18632/oncotarget.24496. eCollection 2018 Mar 20. PMID: 29643989
Journal: Oncotarget; IF 2018 n.d

27) YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation.
Authors: Noce V, Battistelli C, Cozzolino AM, Consalvi V, Cicchini C, Strippoli R, Tripodi M, Marchetti A, Amicone L.
Cell Death Dis. 2019 Oct 10;10(10):768. doi: 10.1038/s41419-019-2000-8. PMID: 31601778
Journal: Cell Death and Disease; IF 2019: 6.304

28) Molecular Mechanisms and New Therapeutic Targets in Epithelial to Mesenchymal Transition (EMT) and Fibrosis.
Authors: Battistelli C, Diederich M, Keane TJ, Sandoval P, Valente S, Strippoli R.
Front Pharmacol. 2020 Jan 16;10:1556. doi: 10.3389/fphar.2019.01556. eCollection 2019. PMID: 32009960
Journal: Frontiers in Pharmacology; IF 2020: 4.225

29) Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation.
Authors: Zwergel C, Fioravanti R, Stazi G, Sarno F, Battistelli C, Romanelli A, Nebbioso A, Mendes E, Paulo A, Strippoli R, Tripodi M, Pechalrieu D, Arimondo PB, De Luca T, Del Bufalo D, Trisciuoglio D, Altucci L, Valente S, Mai A.
Cancers (Basel). 2020 Feb 14;12(2):447. doi: 10.3390/cancers12020447. PMID: 32075099
Journal: Cancers; IF 2020: 6.126

30) Design of First-in-Class Dual EZH2/HDAC Inhibitor: Biochemical Activity and Biological Evaluation in Cancer Cells.
Authors: Romanelli A, Stazi G, Fioravanti R, Zwergel C, Di Bello E, Pomella S, Perrone C, Battistelli C, Strippoli R, Tripodi M, Del Bufalo D, Rota R, Trisciuoglio D, Mai A, Valente S.
ACS Med Chem Lett. 2020 Mar 19;11(5):977-983. doi: 10.1021/acsmedchemlett.0c00014. eCollection 2020 May 14. PMID: 32435414
Journal: ACS Medicinal Chemistry Letters; IF 2020: 3.975

31) Discovery of phenylselenoether-hydantoin hybrids as ABCB1 efflux pump modulating agents with cytotoxic and antiproliferative actions in resistant T-lymphoma.
Authors: Ali W, Spengler G, Kincses A, Nové M, Battistelli C, Latacz G, Starek M, Dąbrowska M, Honkisz-Orzechowska E, Romanelli A, Rasile MM, Szymańska E, Jacob C, Zwergel C, Handzlik J.
Eur J Med Chem. 2020 Aug 15;200:112435. doi: 10.1016/j.ejmech.2020.112435. Epub 2020 May 15. PMID: 32505850
Journal: European Journal of Medicinal Chemistry; IF 2020: 5.572

32) Poly(ADP-ribose) Polymerase 1 (PARP1) restrains MyoD-dependent gene expression during muscle differentiation.
Authors: Matteini F, Andresini O, Petrai S, Battistelli C, Rossi MN, Maione R.
Sci Rep. 2020 Sep 15;10(1):15086. doi: 10.1038/s41598-020-72155-8. PMID: 32934320
Journal: Scientific Reports; IF 2020: 3.998

33) Nutlin-3a enhances Natural Killer cell-mediated killing of neuroblastoma by restoring p53-dependent expression of ligands for NKG2D and DNAM-1 receptors
Authors: I. Veneziani, P. Infante, E. Ferretti, O. Melaiu, C. Battistelli, V. Lucarini, M. Compagnone, C. Nicoletti, A. Castellano, S. Petrini, M. Ognibene, A. Pezzolo, L. Di Marcotullio, L. Moretta, R. Bei, V. Pistoia, D. Fruci, V. Barnaba, F. Locatelli, and L. Cifaldi
Cancer Immunology Research, 2021, 9(2), pp. 170–183
Journal: Cancer Immunology Resarch, IF 2020: 8.728

34) Natural Product Epigenetic Modulators and Inhibitors
Authors: Ntie-Kang, F., Karaman Mayack, B., Valente, S., Battistelli, C.
Frontiers in Pharmacology, 2021, 12, 651395
Journal: Frontiers in Pharmacology; IF 2020: 4.225

35) A novel RNA-based approach to counteract EMT
Authors. Garbo S., Tripodi M., Battistelli C.
Journal: Oncoscience; IF 2020: 3.16

36) SYNCRIP Modulates the Epithelial-Mesenchymal Transition in Hepatocytes and HCC Cells
Authors: Riccioni, V., Trionfetti, F., Montaldo, C., Garbo, S., Marocco, F,. Battistelli, C., Marchetti, A., Strippoli, R., Amicone, L., Cicchini, C., Tripodi, M.
Journal: International Journal of Molecular Sciences; IF 2021: 5.923

37) Fibrogenic signals persist in DAA-treated HCV patients after sustained virological response.
Authors: Montaldo, C., Terri, M., Riccioni, V., Battistelli, C., Bordoni, V., D'Offizi, G., Prado, M.G., Trionfetti, F., Vescovo, T., Tartaglia, E., Strippoli, R., Agrati, C., Tripodi M.
Journal: Journal of Hepatology; IF 2021: 25.083

38) m6A RNA methylation and beyond–the epigenetic machinery and potential treatment options
Authors: Garbo, S., Zwergel, C., Battistelli, C.
Journal: Drug discovery today; IF 2021: 7.851


Research products

11573/1712838 - 2024 - m6A modification inhibits miRNAs’ intracellular function, favoring their extracellular export for intercellular communication
Garbo, S.; D'andrea, D.; Colantoni, A.; Fiorentino, F.; Mai, A.; Ramos, A.; Tartaglia, G. G.; Tancredi, A.; Tripodi, M.; Battistelli, C. - 01a Articolo in rivista
paper: CELL REPORTS (Elsevier B.V. Cambridge MA: Cell Press) pp. - - issn: 2211-1247 - wos: (0) - scopus: 2-s2.0-85195878545 (1)

11573/1712250 - 2024 - Selenium-containing compounds. A new hope for innovative treatments in Alzheimer’s disease and Parkinson’s disease
Pyka, Patryk; Garbo, Sabrina; Fioravanti, Rossella; Jacob, Claus; Hittinger, Marius; Handzlik, Jadwiga; Zwergel, Clemens; Battistelli, Cecilia - 01g Articolo di rassegna (Review)
paper: DRUG DISCOVERY TODAY (Elsevier Science Limited Trends Journals:PO Box 331, Haywards Heath RH16 3FG United Kingdom:011 44 1444 475651, EMAIL: ct.subs@rbi.co.uk, Fax: 011 44 1444 445423) pp. 1-16 - issn: 1359-6446 - wos: WOS:001332975900001 (0) - scopus: 2-s2.0-85196322621 (3)

11573/1716603 - 2024 - Unlocking the potential of higher-molecular-weight 5-HT7R ligands. Synthesis, affinity, and ADMET examination
Pyka, Patryk; Garbo, Sabrina; Murzyn, Aleksandra; Satała, Grzegorz; Janusz, Artur; Górka, Michał; Pietruś, Wojciech; Mituła, Filip; Popiel, Delfina; Wieczorek, Maciej; Palmisano, Biagio; Raucci, Alessia; Bojarski, Andrzej J.; Zwergel, Clemens; Szymańska, Ewa; Kucwaj-Brysz, Katarzyna; Battistelli, Cecilia; Handzlik, Jadwiga; Podlewska, Sabina - 01a Articolo in rivista
paper: BIOORGANIC CHEMISTRY (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 1-20 - issn: 0045-2068 - wos: WOS:001284368500001 (0) - scopus: 2-s2.0-85199923673 (0)

11573/1700590 - 2024 - First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT6 Agents with a Beneficial Neuroprotective Profile against Alzheimer's Disease
Pyka, Patryk; Haberek, Wawrzyniec; Więcek, Małgorzata; Szymanska, Ewa; Ali, Wesam; Cios, Agnieszka; Jastrzębska-Więsek, Magdalena; Satała, Grzegorz; Podlewska, Sabina; Di Giacomo, Silvia; Di Sotto, Antonella; Garbo, Sabrina; Karcz, Tadeusz; Lambona, Chiara; Marocco, Francesco; Latacz, Gniewomir; Sudoł-Tałaj, Sylwia; Mordyl, Barbara; Głuch-Lutwin, Monika; Siwek, Agata; Czarnota-Łydka, Kinga; Gogola, Dawid; Olejarz-Maciej, Agnieszka; Wilczyńska-Zawal, Natalia; Honkisz-Orzechowska, Ewelina; Starek, Małgorzata; Dąbrowska, Monika; Kucwaj-Brysz, Katarzyna; Fioravanti, Rossella; Nasim, Muhammad Jawad; Hittinger, Marius; Partyka, Anna; Wesołowska, Anna; Battistelli, Cecilia; Zwergel, Clemens; Handzlik, Jadwiga - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 1580-1610 - issn: 1520-4804 - wos: WOS:001151429000001 (5) - scopus: 2-s2.0-85182565496 (7)

11573/1700487 - 2024 - HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling
Terri, Michela; Sandoval, Pilar; Bontempi, Giulio; Montaldo, Claudia; Tomero-Sanz, Henar; De Turris, Valeria; Trionfetti, Flavia; Pascual-Antón, Lucía; Clares-Pedrero, Irene; Battistelli, Cecilia; Valente, Sergio; Zwergel, Clemens; Mai, Antonello; Rosanò, Laura; Del Pozo, Miguel Ángel; Sánchez-Álvarez, Miguel; Cabañas, Carlos; Tripodi, Marco; López-Cabrera, Manuel; Strippoli, Raffaele - 01a Articolo in rivista
paper: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. - - issn: 1756-9966 - wos: WOS:001147742000001 (1) - scopus: 2-s2.0-85182865073 (1)

11573/1690688 - 2023 - Interaction of Garcinia cambogia (Gaertn.) Desr. and Drugs as a Possible Mechanism of Liver Injury: The Case of Montelukast
Di Giacomo, Silvia; Di Sotto, Antonella; Percaccio, Ester; Scuotto, Erica; Battistelli, Cecilia; Mazzanti, Gabriela; Menniti-Ippolito, Francesca; Ippoliti, Ilaria - 01a Articolo in rivista
paper: ANTIOXIDANTS (Basel: MDPI) pp. 1-23 - issn: 2076-3921 - wos: WOS:001072869500001 (0) - scopus: 2-s2.0-85172195272 (0)

11573/1663202 - 2023 - Selenium-containing agents acting on cancer. A new hope?
Garbo, Sabrina; Di Giacomo, Silvia; Łażewska, Dorota; Honkisz-Orzechowska, Ewelina; Di Sotto, Antonella; Fioravanti, Rossella; Zwergel, Clemens; Battistelli, Cecilia - 01g Articolo di rassegna (Review)
paper: PHARMACEUTICS (Basel: MDPI, 2009-) pp. 1-32 - issn: 1999-4923 - wos: WOS:000915696500001 (20) - scopus: 2-s2.0-85146819962 (18)

11573/1680927 - 2023 - Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity
Ippolito, Francesca; Consalvi, Veronica; Noce, Valeria; Battistelli, Cecilia; Cicchini, Carla; Tripodi, Marco; Amicone, Laura; Marchetti, Alessandra - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. 1-14 - issn: 2041-4889 - wos: WOS:000937972600002 (4) - scopus: 2-s2.0-85146405660 (4)

11573/1696065 - 2023 - HDAC1-3 inhibition increases SARS-CoV-2 replication and productive infection in lung mesothelial and epithelial cells
Trionfetti, Flavia; Alonzi, Tonino; Bontempi, Giulio; Terri, Michela; Battistelli, Cecilia; Montaldo, Claudia; Repele, Federica; Rotili, Dante; Valente, Sergio; Zwergel, Clemens; Matusali, Giulia; Maggi, Fabrizio; Goletti, Delia; Tripodi, Marco; Mai, Antonello; Strippoli, Raffaele - 01a Articolo in rivista
paper: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (Lausanne : Frontiers Media SA, 2011-) pp. - - issn: 2235-2988 - wos: WOS:001130489700001 (3) - scopus: 2-s2.0-85180885673 (3)

11573/1684985 - 2023 - Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells
Zwergel, Clemens; Aventaggiato, Michele; Garbo, Sabrina; Di Bello, Elisabetta; Fassari, Bruno; Noce, Beatrice; Castiello, Carola; Lambona, Chiara; Barreca, Federica; Rotili, Dante; Fioravanti, Rossella; Schmalz, Thomas; Weyand, Michael; Niedermeier, Amelie; Tripodi, Marco; Colotti, Gianni; Steegborn, Clemens; Battistelli, Cecilia; Tafani, Marco; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9622-9641 - issn: 0022-2623 - wos: WOS:001027732800001 (9) - scopus: 2-s2.0-85165671509 (9)

11573/1655432 - 2022 - Seleno-vs. thioether triazine derivatives in search for new anticancer agents overcoming multidrug resistance in lymphoma
Ali, Wesam; Garbo, Sabrina; Kincses, Annamária; Nové, Márta; Spengler, Gabriella; Di Bello, Elisabetta; Honkisz-Orzechowska, Ewelina; Karcz, Tadeusz; Szymańska, Ewa; Żesławska, Ewa; Starek, Małgorzata; Dąbrowska, Monika; Nitek, Wojciech; Kucwaj-Brysz, Katarzyna; Pyka, Patryk; Fioravanti, Rossella; Jacob, Claus; Battistelli, Cecilia; Zwergel, Clemens; Handzlik, Jadwiga - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000870590900002 (13) - scopus: 2-s2.0-85139065541 (13)

11573/1714681 - 2022 - Editorial: Molecular mechanisms and new therapeutic targets in epithelial to mesenchymal transition (EMT) and fibrosis, volume II
Battistelli, C.; Diederich, M.; Keane, T. J.; Sandoval, P.; Valente, S.; Strippoli, R. - 01m Editorial/Introduzione in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000860329800001 (0) - scopus: 2-s2.0-85138346687 (0)

11573/1680930 - 2022 - Persistence of fibrogenic process in direct-acting antiviral (DAA) treated patients?
Battistelli, C.; Tripodi, M. - 01f Lettera, Nota
paper: EXRNA (London: BioMed Central Ltd) pp. 15-15 - issn: 2398-0060 - wos: (0) - scopus: 2-s2.0-85134047038 (0)

11573/1660735 - 2022 - MyoD-Induced Trans-Differentiation: A Paradigm for Dissecting the Molecular Mechanisms of Cell Commitment, Differentiation and Reprogramming
Battistelli, Cecilia; Garbo, Sabrina; Maione, Rossella - 01g Articolo di rassegna (Review)
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 3435- - issn: 2073-4409 - wos: WOS:000882621300001 (6) - scopus: 2-s2.0-85141777972 (9)

11573/1659806 - 2022 - Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells
Bontempi, Giulio; Terri, Michela; Garbo, Sabrina; Montaldo, Claudia; Mariotti, Davide; Bordoni, Veronica; Valente, Sergio; Zwergel, Clemens; Mai, Antonello; Marchetti, Alessandra; Domenici, Alessandro; Menè, Paolo; Battistelli, Cecilia; Tripodi, Marco; Strippoli, Raffaele - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. 965- - issn: 2041-4889 - wos: WOS:000885083500004 (10) - scopus: 2-s2.0-85142134241 (13)

11573/1650846 - 2022 - Next RNA therapeutics: the mine of non-coding
Garbo, Sabrina; Maione, Rossella; Tripodi, Marco; Battistelli, Cecilia - 01g Articolo di rassegna (Review)
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000825641900001 (36) - scopus: 2-s2.0-85133395869 (38)

11573/1680931 - 2022 - lncRNA HOTAIR functions and therapeutic perspectives
Garbo, Sabrina; Tripodi, Marco; Battistelli, Cecilia - 01h Abstract in rivista
paper: ONCOSCIENCE (Impact Journals LLC -) pp. 49-51 - issn: 2331-4737 - wos: (0) - scopus: (0)

11573/1605129 - 2022 - SYNCRIP Modulates the Epithelial-Mesenchymal Transition in Hepatocytes and HCC Cells
Riccioni, V.; Trionfetti, F.; Montaldo, C.; Garbo, S.; Marocco, F.; Battistelli, C.; Marchetti, A.; Strippoli, R.; Amicone, L.; Cicchini, C.; Tripodi, M. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 913- - issn: 1661-6596 - wos: WOS:000748109700001 (7) - scopus: 2-s2.0-85122801338 (7)

11573/1627263 - 2022 - SYNCRIP modulates the epithelial-mesenchymal transition in hepatocytes and HCC Cells
Riccioni, V.; Trionfetti, F.; Montaldo, C.; Garbo, S.; Marocco, F.; Battistelli, C.; Marchetti, A.; Strippoli, R.; Amicone, L.; Cicchini, C.; Tripodi, M. - 04f Poster
conference: ABCD National Ph.D. Meeting (Salerno; Italy)
book: National Ph.D. Meeting Abstracts book - ()

11573/1657751 - 2022 - A novel microRNA signature for the detection of melanoma by liquid biopsy
Sabato, Claudia; Noviello, Teresa Maria Rosaria; Covre, Alessia; Coral, Sandra; Caruso, Francesca Pia; Besharat, Zein Mersini; Splendiani, Elena; Masuelli, Laura; Battistelli, Cecilia; Vacca, Alessandra; Catanzaro, Giuseppina; Po, Agnese; Anichini, Andrea; Maio, Michele; Ceccarelli, Michele; Di Giacomo, Anna Maria; Ferretti, Elisabetta - 01a Articolo in rivista
paper: JOURNAL OF TRANSLATIONAL MEDICINE (London: BioMed Central, London) pp. - - issn: 1479-5876 - wos: WOS:000868387300003 (11) - scopus: 2-s2.0-85139885995 (12)

11573/1467236 - 2021 - The innovative potential of selenium-containing agents for fighting cancer and viral infections
Ali, W.; Benedetti, R.; Handzlik, J.; Zwergel, C.; Battistelli, C. - 01g Articolo di rassegna (Review)
paper: DRUG DISCOVERY TODAY (Elsevier Science Limited Trends Journals:PO Box 331, Haywards Heath RH16 3FG United Kingdom:011 44 1444 475651, EMAIL: ct.subs@rbi.co.uk, Fax: 011 44 1444 445423) pp. 256-263 - issn: 1359-6446 - wos: WOS:000632655800011 (49) - scopus: 2-s2.0-85096386344 (53)

11573/1565876 - 2021 - Editorial: new approaches to tackle EMT and fibrosis: from epigenetics to nanotechnology
Battistelli, Cecilia; Cordani, Marco; Diederich, Marc; Somoza, Álvaro; Valente, Sergio; Strippoli, Raffaele - 01m Editorial/Introduzione in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000686867300001 (1) - scopus: 2-s2.0-85113221898 (0)

11573/1471921 - 2021 - Design and functional validation of a mutant variant of the lncRNA HOTAIR to counteract Snail function in Epithelial-to-Mesenchymal Transition
Battistelli, Cecilia; Garbo, Sabrina; Riccioni, Veronica; Montaldo, Claudia; Santangelo, Laura; Vandelli, Andrea; Strippoli, Raffaele; Tartaglia, Gian Gaetano; Tripodi, Marco; Cicchini, Carla - 01a Articolo in rivista
paper: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 103-113 - issn: 0008-5472 - wos: WOS:000606529700011 (38) - scopus: 2-s2.0-85100339265 (41)

11573/1613679 - 2021 - A novel RNA-based approach to counteract EMT
Garbo, Sabrina; Tripodi, Marco; Battistelli, Cecilia - 01m Editorial/Introduzione in rivista
paper: ONCOSCIENCE (Impact Journals LLC -) pp. 53-54 - issn: 2331-4737 - wos: (0) - scopus: (0)

11573/1552435 - 2021 - m6A RNA methylation and beyond - the epigenetic machinery and potential treatment options
Garbo, Sabrina; Zwergel, Clemens; Battistelli, Cecilia - 01g Articolo di rassegna (Review)
paper: DRUG DISCOVERY TODAY (Elsevier Science Limited Trends Journals:PO Box 331, Haywards Heath RH16 3FG United Kingdom:011 44 1444 475651, EMAIL: ct.subs@rbi.co.uk, Fax: 011 44 1444 445423) pp. 2559-2574 - issn: 1359-6446 - wos: WOS:000721315300009 (58) - scopus: 2-s2.0-85108951501 (58)

11573/1571274 - 2021 - Fibrogenic signals persist in DAA-treated HCV patients after sustained virological response
Montaldo, Claudia; Terri, Michela; Riccioni, Veronica; Battistelli, Cecilia; Bordoni, Veronica; D'offizi, Gianpiero; Prado, Maria Giulia; Trionfetti, Flavia; Vescovo, Tiziana; Tartaglia, Eleonora; Strippoli, Raffaele; Agrati, Chiara; Tripodi, Marco - 01a Articolo in rivista
paper: JOURNAL OF HEPATOLOGY (Blackwell Munksgaard:PO Box 2148, Periodicals Department, DK-1016 Copenhagen K Denmark:011 45 33 755913, EMAIL: agentservices@oxon.blackwellpublishing.com, INTERNET: http://www.blackwellmunksgaard.com, Fax: 011 45 77 333377) pp. 1301-1311 - issn: 0168-8278 - wos: WOS:000727375100007 (20) - scopus: 2-s2.0-85114987180 (28)

11573/1613681 - 2021 - Editorial: Natural Product Epigenetic Modulators and Inhibitors
Ntie-Kang, Fidele; Karaman Mayack, Berin; Valente, Sergio; Battistelli, Cecilia - 01m Editorial/Introduzione in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000629965700001 (2) - scopus: 2-s2.0-85102865581 (4)

11573/1471927 - 2021 - Nutlin-3a enhances natural killer cell-mediated killing of neuroblastoma by restoring p53-dependent expression of ligands for NKG2D and DNAM-1 receptors
Veneziani, Irene; Infante, Paola; Ferretti, Elisa; Melaiu, Ombretta; Battistelli, Cecilia; Lucarini, Valeria; Compagnone, Mirco; Nicoletti, Carmine; Castellano, Aurora; Petrini, Stefania; Ognibene, Marzia; Pezzolo, Annalisa; Di Marcotullio, Lucia; Bei, Roberto; Moretta, Lorenzo; Pistoia, Vito; Fruci, Doriana; Barnaba, Vincenzo; Locatelli, Franco; Cifaldi, Loredana - 01a Articolo in rivista
paper: CANCER IMMUNOLOGY RESEARCH (American Association for Cancer Research, Inc. (AACR), 615 Chestnut St., 17th Floor Philadelphia, PA 19106-4404; Phone: (215) 440-9300 or Toll Free: (866) 423-3965; Fax: (215) 446-7289; E-mail: cancerimmunolres@aacr.org.) pp. 170-183 - issn: 2326-6066 - wos: WOS:000618209900006 (21) - scopus: 2-s2.0-85100390757 (31)

11573/1406895 - 2020 - Discovery of phenylselenoether-hydantoin hybrids as ABCB1 efflux pump modulating agents with cytotoxic and antiproliferative actions in resistant T-lymphoma
Ali, Wesam; Spengler, Gabriella; Kincses, Annamária; Nové, Márta; Battistelli, Cecilia; Latacz, Gniewomir; Starek, Małgorzata; Dąbrowska, Monika; Honkisz-Orzechowska, Ewelina; Romanelli, Annalisa; Rasile, Manuela Monica; Szymańska, Ewa; Jacob, Claus; Zwergel, Clemens; Handzlik, Jadwiga - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000546723400026 (31) - scopus: 2-s2.0-85085687764 (35)

11573/1361035 - 2020 - Molecular mechanisms and new therapeutic targets in epithelial to mesenchymal transition (EMT) and fibrosis
Battistelli, Cecilia; Diederich, Marc; Keane, Tj; Sandoval, Pilar; Valente, Sergio; Strippoli, Raffaele - 01m Editorial/Introduzione in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000510209700001 (2) - scopus: 2-s2.0-85078745922 (2)

11573/1438956 - 2020 - Poly(ADP-ribose) Polymerase 1 (PARP1) restrains MyoD-dependent gene expression during muscle differentiation
Matteini, Francesca; Andresini, Oriella; Petrai, Stefano; Battistelli, Cecilia; Rossi, Marianna Nicoletta; Maione, Rossella - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000573753200026 (7) - scopus: 2-s2.0-85090991653 (7)

11573/1394955 - 2020 - Design of first-in-class dual EZH2/HDAC inhibitor: biochemical activity and biological evaluation in cancer cells
Romanelli, Annalisa; Stazi, Giulia; Fioravanti, Rossella; Zwergel, Clemens; Di Bello, Elisabetta; Pomella, Silvia; Perrone, Clara; Battistelli, Cecilia; Strippoli, Raffaele; Tripodi, Marco; Del Bufalo, Donatella; Rota, Rossella; Trisciuoglio, Daniela; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 977-983 - issn: 1948-5875 - wos: WOS:000535281200056 (48) - scopus: 2-s2.0-85087681122 (51)

11573/1435589 - 2020 - Caveolin1 and YAP drive mechanically induced mesothelial to mesenchymal transition and fibrosis
Strippoli, Raffaele; Sandoval, Pilar; Moreno-Vicente, Roberto; Rossi, Lucia; Battistelli, Cecilia; Terri, Michela; Pascual-Antón, Lucía; Loureiro, Marta; Matteini, Francesca; Calvo, Enrique; 9, José Antonio Jiménez-Heffernan; José Gómez 10, Manuel; Jiménez-Jiménez, Victor; Sánchez-Cabo, Fátima; Vázquez, Jesús; Tripodi, Marco; López-Cabrera, Manuel; Ángel Del Pozo, Miguel - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000579809200002 (32) - scopus: 2-s2.0-85089528848 (32)

11573/1364390 - 2020 - Novel quinoline compounds active in cancer cells through coupled DNA methyltransferase inhibition and degradation
Zwergel, C.; Fioravanti, R.; Stazi, G.; Sarno, F.; Battistelli, C.; Romanelli, A.; Nebbioso, A.; Mendes, E.; Paulo, A.; Strippoli, R.; Tripodi, M.; Pechalrieu, D.; Arimondo, P. B.; De Luca, T.; Del Bufalo, D.; Trisciuoglio, D.; Altucci, L.; Valente, S.; Mai, A. - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000522477300193 (7) - scopus: 2-s2.0-85079504263 (7)

11573/1137806 - 2019 - The lncRNA HOTAIR transcription is controlled by HNF4α-induced chromatin topology modulation
Battistelli, Cecilia; Sabarese, Giovanna; Santangelo, Laura; Montaldo, Claudia; Gonzalez, Frank J; Tripodi, Marco; Cicchini, Carla - 01a Articolo in rivista
paper: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 890-901 - issn: 1350-9047 - wos: WOS:000463873100009 (61) - scopus: 2-s2.0-85052935306 (63)

11573/1308040 - 2019 - TGFβ impairs HNF1α functional activity in Epithelial-to-Mesenchymal Transition interfering with the recruitment of CBP/p300 acetyltransferases
Bisceglia, Francesca; Battistelli, Cecilia; Noce, Valeria; Montaldo, Claudia; Zammataro, Agatino; Strippoli, Raffaele; Tripodi, Marco; Amicone, Laura; Marchetti, Alessandra - 01a Articolo in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000483322300001 (10) - scopus: 2-s2.0-85070663914 (11)

11573/1680928 - 2019 - In vivo Bioluminescence-Based Monitoring of Liver Metastases from Colorectal Cancer: An Experimental Model
Magistri, Paolo; Battistelli, Cecilia; Toietta, Gabriele; Strippoli, Raffaele; Sagnotta, Andrea; Forgione, Antonello; Di Benedetto, Fabrizio; Uccini, Stefania; Vittorioso, Paola; D'angelo, Francesco; Aurello, Paolo; Ramacciato, Giovanni; Nigri, Giuseppe - 01a Articolo in rivista
paper: JOURNAL OF MICROSCOPY AND ULTRASTRUCTURE (Elsevier B.V.) pp. 136-140 - issn: 2213-879X - wos: (0) - scopus: 2-s2.0-85095753295 (4)

11573/1321281 - 2019 - YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation
Noce, Valeria; Battistelli, Cecilia; Cozzolino, Angela Maria; Consalvi, Veronica; Cicchini, Carla; Strippoli, Raffaele; Tripodi, Marco; Marchetti, Alessandra; Amicone, Laura - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000490001800007 (29) - scopus: 2-s2.0-85073113246 (30)

11573/1208206 - 2019 - Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells
Stazi, Giulia; Battistelli, Cecilia; Piano, Valentina; Mazzone, Roberta; Marrocco, Biagina; Marchese, Sara; Louie, Sharon M.; Zwergel, Clemens; Antonini, Lorenzo; Patsilinakos, Alexandros; Ragno, Rino; Viviano, Monica; Sbardella, Gianluca; Ciogli, Alessia; Fabrizi, Giancarlo; Cirilli, Roberto; Strippoli, Raffaele; Marchetti, Alessandra; Tripodi, Marco; Nomura, Daniel K.; Mattevi, Andrea; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 722-735 - issn: 0223-5234 - wos: WOS:000458597300053 (15) - scopus: 2-s2.0-85058530369 (17)

11573/1265927 - 2019 - Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells
Zwergel, Clemens; Schnekenburger, Michael; Sarno, Federica; Battistelli, Cecilia; Manara, Maria Cristina; Stazi, Giulia; Mazzone, Roberta; Fioravanti, Rossella; Gros, Christina; Ausseil, Frédéric; Florean, Cristina; Nebbioso, Angela; Strippoli, Raffaele; Ushijima, Toshikazu; Scotlandi, Katia; Tripodi, Marco; Arimondo, Paola B.; Altucci, Lucia; Diederich, Marc; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. - - issn: 1868-7083 - wos: WOS:000467227900001 (27) - scopus: 2-s2.0-85065468885 (30)

11573/1120944 - 2018 - The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter
Fazi, Barbara; Garbo, Sabrina; Toschi, Nicola; Mangiola, Annunziato; Lombari, Malinska; Sicari, Daria; Battistelli, Cecilia; Galardi, Silvia; Michienzi, Alessandro; Trevisi, Gianluca; Harari-Steinfeld, Rona; Cicchini, Carla; Ciafrè, Silvia Anna - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 15512-15525 - issn: 1949-2553 - wos: (0) - scopus: 2-s2.0-85044251177 (40)

11573/1073253 - 2018 - A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets
Hobor, Fruzsina; Dallmann, Andre; Ball, Neil J.; Cicchini, Carla; Battistelli, Cecilia; Ogrodowicz, Roksana W.; Christodoulou, Evangelos; Martin, Stephen R.; Castello, Alfredo; Tripodi, Marco; Taylor, Ian A.; Ramos, Andres - 01a Articolo in rivista
paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. - - issn: 2041-1723 - wos: WOS:000426049100004 (85) - scopus: 2-s2.0-85043235442 (86)

11573/1069660 - 2018 - SMO inhibition modulates cellular plasticity and invasiveness in colorectal cancer
Magistri, Paolo; Battistelli, Cecilia; Strippoli, Raffaele; Petrucciani, Niccolò; Pellinen, Teijo; Rossi, Lucia; Mangogna, Livia Maria; Aurello, Paolo; D'angelo, Francesco; Tripodi, Marco; Ramacciato, Giovanni; Nigri, Giuseppe - 01a Articolo in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. 1-13 - issn: 1663-9812 - wos: WOS:000423986600001 (27) - scopus: 2-s2.0-85041821519 (28)

11573/1120934 - 2018 - HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal
Rossi, Lucia; Battistelli, Cecilia; De Turris, Valeria; Noce, Valeria; Zwergel, Clemens; Valente, Sergio; Moioli, Alessandra; Manzione, Andrea; Palladino, Marco; Bordoni, Veronica; Domenici, Alessandro; Mene', Paolo; Mai, Antonello; Tripodi, Marco; Strippoli, Raffaele - 01a Articolo in rivista
paper: OPEN ACCESS SCIENTIFIC REPORTS (Los Angeles, CA : OMICS Publishing Group, [2012]-) pp. - - issn: 2332-2675 - wos: WOS:000433547600053 (23) - scopus: 2-s2.0-85048002226 (25)

11573/1080338 - 2018 - Hepatitis C virus direct-acting antivirals therapy impacts on extracellular vesicles microRNAs content and on their immunomodulating properties
Santangelo, Laura; Bordoni, Veronica; Montaldo, Claudia; Cimini, Eleonora; Zingoni, Alessandra; Battistelli, Cecilia; D'offizi, Gianpiero; Capobianchi, Maria R.; Santoni, Angela; Tripodi, Marco; Agrati, Chiara - 01a Articolo in rivista
paper: LIVER INTERNATIONAL (-MALDEN, USA: WILEY-BLACKWELL PUBLISHING -Copenhagen K Denmark: Blackwell Munksgaard) pp. 1741-1750 - issn: 1478-3223 - wos: WOS:000445622400006 (40) - scopus: 2-s2.0-85042376688 (43)

11573/882097 - 2017 - The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition
Battistelli, Cecilia; Cicchini, Carla; Santangelo, L.; Tramontano, Anna; Grassi, L.; Gonzalez, F. J.; De Nonno, Valeria; Grassi, Germana; Amicone, Laura; Tripodi, Marco - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 1-1 - issn: 0950-9232 - wos: WOS:000394169100007 (133) - scopus: 2-s2.0-84979641106 (146)
conference: XVII congresso nazionale AIBG (Associazione Italiana di Biologia e Genetica Generale e Molecolare) (Cagliari)

11573/1696381 - 2017 - The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition
Battistelli, Cecilia; Cicchini, Carla; Santangelo, Laura; Tramontano, Anna; Grassi, L; Gonzalez, Frank J; De Nonno, Valeria; Grassi, G; Amicone, L; Tripodi, Marco - 01a Articolo in rivista
paper: ONCOGENE (Basingstoke: Nature Publishing Group.) pp. 942-955 - issn: 1476-5594 - wos: WOS:000394169100007 (132) - scopus: 2-s2.0-84979641106 (145)

11573/1073251 - 2017 - Targeting of polycombs to DNA in EMT
Battistelli, Cecilia; Tripodi, Marco; Cicchini, Carla - 01m Editorial/Introduzione in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 57936-57937 - issn: 1949-2553 - wos: WOS:000408941900002 (4) - scopus: 2-s2.0-85029073203 (4)

11573/1158807 - 2017 - Promotion of proliferation and metastasis of hepatocellular carcinoma by LncRNA00673 based on the targeted-regulation of notch signaling pathway
Magistri, P; Battistelli, C; Assirati, G; Mereu, F; Tarantino, G; Guerrini, Gp; Ballarin, R; Di Benedetto, F - 01a Articolo in rivista
paper: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES (Roma: Verduci publisher) pp. 4261-4262- - issn: 2284-0729 - wos: WOS:000415151500001 (1) - scopus: 2-s2.0-85042871693 (1)

11573/946056 - 2017 - Functional Roles and Therapeutic Applications of Exosomes in Hepatocellular Carcinoma
Santangelo, Laura; Battistelli, Cecilia; Montaldo, Claudia; Citarella, Franca; Strippoli, Raffaele; Cicchini, Carla - 01a Articolo in rivista
paper: BIOMED RESEARCH INTERNATIONAL ([London]: [Hindawi] Cairo: Hindawi Publishing Corporation) pp. - - issn: 2314-6133 - wos: WOS:000394850800001 (24) - scopus: 2-s2.0-85013276849 (26)

11573/928129 - 2016 - A cross-talk between DNA methylation and H3 lysine 9 dimethylation at the KvDMR1 region controls the induction of Cdkn1c in muscle cells
Andresini, Oriella; Ciotti, Agnese; Rossi, Marianna Nicoletta; Battistelli, Cecilia; Carbone, Mariarosaria; Maione, Rossella - 01a Articolo in rivista
paper: EPIGENETICS (Georgetown, TX : Landes Bioscience,) pp. 791-803 - issn: 1559-2294 - wos: WOS:000388622200003 (14) - scopus: 2-s2.0-84992184136 (14)

11573/895280 - 2016 - The lncRNA HOTAIR links the repressor Snail to epigenetic modifications of specific genomic sites in Epithelial-to-Mesenchymal Transition
Battistelli, C.; Cicchini, Carla; Santangelo, L.; Tramontano, Anna; Tripodi, Marco - 04d Abstract in atti di convegno
conference: XIV FISV (Federazione Italiana Scienze della Vita) Congress (Roma)
book: FISV - Federazione Italiana Scienze della Vita Program and Abstracts of the XIV FISV CONGRESS - ()

11573/960510 - 2016 - SETDB1 is a new promising target in HCC therapy
Cicchini, Carla; Battistelli, Cecilia; Tripodi, Marco - 01a Articolo in rivista
paper: CHINESE CLINICAL ONCOLOGY (Hong Kong : AME Publishing Company) pp. 1-3 - issn: 2304-3865 - wos: WOS:000393128000002 (2) - scopus: 2-s2.0-84994212683 (3)

11573/848794 - 2016 - Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes
Cozzolino, Angela Maria; Noce, Valeria; Battistelli, Cecilia; Marchetti, Alessandra; Grassi, Germana; Cicchini, Carla; Tripodi, Marco; Amicone, Laura - 01a Articolo in rivista
paper: STEM CELLS INTERNATIONAL (Cairo: Hindawi Publishing Corporation) pp. 1-12 - issn: 1687-966X - wos: WOS:000368844000001 (57) - scopus: 2-s2.0-84971261585 (65)

11573/895279 - 2016 - The RNA binding protein SYNCRIP controls microRNAs sorting in exosomes
L., Santangelo*; G., Giurato*; Cicchini, Carla; C., Montaldo; Mancone, Carmine; R., Tarallo; Battistelli, Cecilia; T., Alonzi; A., Weisz; Tripodi, Marco - 04d Abstract in atti di convegno
conference: XIV FISV (Federazione Italiana Scienze della Vita) Congress (Roma)
book: FISV - Federazione Italiana Scienze della Vita Program and Abstracts of the XIV FISV CONGRESS - ()

11573/960504 - 2016 - The RNA-Binding Protein SYNCRIP Is a Component of the Hepatocyte Exosomal Machinery Controlling MicroRNA Sorting
Santangelo, Laura; Giurato, Giorgio; Cicchini, Carla; Montaldo, Claudia; Mancone, Carmine; Tarallo, Roberta; Battistelli, Cecilia; Alonzi, Tonino; Weisz, Alessandro; Tripodi, Marco - 01a Articolo in rivista
paper: CELL REPORTS (Elsevier B.V. Cambridge MA: Cell Press) pp. 799-808 - issn: 2211-1247 - wos: WOS:000385852300017 (419) - scopus: 2-s2.0-84992197875 (446)

11573/867038 - 2016 - Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis
Strippoli, Raffaele; Moreno Vicente, Roberto; Battistelli, Cecilia; Cicchini, Carla; Noce, Valeria; Amicone, Laura; Marchetti, Alessandra; Del Pozo, Miguel Angel; Tripodi, Marco - 01g Articolo di rassegna (Review)
paper: STEM CELLS INTERNATIONAL (SAGE-Hindawi) pp. - - issn: 1687-9678 - wos: WOS:000373040900001 (111) - scopus: 2-s2.0-84959440932 (122)

11573/895462 - 2015 - A lncRNA-mediated interaction between Snail and Ezh2 governs epigenetic modifications causal to EMT of the hepatocyte
Battistelli, Cecilia; Cicchini, Carla; Santangelo, Laura; Tramontano, Anna; Amicone, Laura; Tripodi, Marco - 04d Abstract in atti di convegno
conference: Coding and non-coding functions of the genome (3rd Barcelona Conferences on Epigenetics and Cancer (BCEC)) (Barcellona (Spagna))

11573/895463 - 2015 - A lncRNA-mediated interaction between Snail and Ezh2 governs epigenetic modifications causal to EMT of the hepatocyte
Battistelli, Cecilia; Cicchini, Carla; Santangelo, Laura; Tramontano, Anna; Amicone, Laura; Tripodi, Marco - 04d Abstract in atti di convegno
conference: ABCD (Associazione di Biologia Cellulare e del Differenziamento) biennial congress 2015 (Bologna (IT))
book: ABCD congress 2015, The biennial congress of italian association of cell biology and differentiation - ()

11573/895465 - 2015 - A lncRNA-mediated interaction between Snail and Ezh2 governs epigenetic modifications causal to EMT of the hepatocyte
Battistelli, Cecilia; Cicchini, Carla; Santangelo, Laura; Tramontano, Anna; Amicone, Laura; Tripodi, Marco - 04d Abstract in atti di convegno
conference: The multi-faceted non coding RNA landscape – RNA day 2015, organizzato dal dipartimento di Biologia e biotecnologie “Charles Darwin”, in collaborazione con l’istituto di Biologia e patologia molecolari del Consiglio nazionale delle ricerche (Cnr). (Roma)

11573/789121 - 2015 - Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29
Cicchini, Carla; De Nonno, Valeria; Battistelli, Cecilia; Cozzolino, Angela Maria; De Santis Puzzonia, Marco; Ciafrè, Silvia Anna; Brocker, Chad; Gonzalez, Frank J.; Amicone, Laura; Tripodi, Marco - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS (Amsterdam-UK : Elsevier) pp. 919-929 - issn: 1874-9399 - wos: WOS:000358969000002 (53) - scopus: 2-s2.0-84935031617 (59)

11573/895466 - 2014 - DNMT3s and miRs-29 in EMT/MET dynamics: a role for HNF4α
Battistelli, C.; Cicchini, Carla; De Nonno, V.; De Santis Puzzonia, M.; Ciafrè, S. A.; Amicone, Laura; Tripodi, Marco - 04d Abstract in atti di convegno
conference: FISV (Federazione Italiana Scienze della Vita) 2014-XIII Congress (Pisa (IT))

11573/577384 - 2014 - Functional interplay between MyoD and CTCF in regulating long-range chromatin interactions during differentiation
Battistelli, Cecilia; Busanello, Anna; Maione, Rossella - 01a Articolo in rivista
paper: JOURNAL OF CELL SCIENCE (The Company of Biologists Limited:Bidder Building, 140 Cowley Road, Cambridge CB4 0DL United Kingdom:011 44 1223 420482, EMAIL: mandy@thecob.demon.co.uk, INTERNET: http://www.biologists.com, Fax: 011 44 1223 423353) pp. 3757-3767 - issn: 0021-9533 - wos: WOS:000341698300012 (33) - scopus: 2-s2.0-84906877432 (35)

11573/895281 - 2014 - Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29
Cicchini, Carla; V., De Nonno; Battistelli, Cecilia; A. M., Cozzolino; S. A., Ciafrè; Amicone, Laura; Tripodi, Marco - 04a Atto di comunicazione a congresso
conference: XVI Congresso Nazionale ASSOCIAZIONE ITALIANA DI BIOLOGIA E GENETICA GENERALE E MOLECOLARE (Napoli (IT))

11573/549762 - 2014 - Spike-in SILAC proteomic approach reveals the vitronectin as an early molecular signature of liver fibrosis in Hepatitis C infections with hepatic iron overload
Claudia, Montaldo; Simone, Mattei; Andrea, Baiocchini; Nicolina, Rotiroti; Franca Del Nonno, ; Leopoldo Paolo Pucillo, ; Angela Maria Cozzolino, ; Battistelli, Cecilia; Amicone, Laura; Giuseppe, Ippolito; Vera Van Noort, ; Alice, Conigliaro; Tonino, Alonzi; Tripodi, Marco; Mancone, Carmine - 01a Articolo in rivista
paper: PROTEOMICS (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 1107-1115 - issn: 1615-9853 - wos: WOS:000334290600019 (12) - scopus: 2-s2.0-84898630514 (12)

11573/853589 - 2014 - Identification of the molecular events underlying liver stem cell choices at the branch of epithelial/mesenchymal differentiation
Cozzolino, A. M.; Noce, Valeria; Battistelli, Cecilia; Grassi, Germana; Cicchini, Carla; Amicone And M. Tripodi, L. Amicone And M. Tripodi - 04d Abstract in atti di convegno
conference: Stem Cell Research Italy (Salerno)

11573/853565 - 2014 - Role of different matrix stiffness on RLSCS (resident liver stem cells) fate. School of Pure and Applied Biophysicson "Nanomechanics in biomolecular adhesion" Gennaio27-31, 2014, Venezia, Italy
Cozzolino, Angela Maria; Noce, Valeria; Battistelli, Cecilia; Grassi, Germana; Santangelo, Laura; Amicone And M. Tripodi, L. Amicone And M. Tripodi - 04f Poster
conference: School of Pure and Applied Biophysicson "Nanomechanics in biomolecular adhesion" (Venice)

11573/577385 - 2014 - Poly(ADP-ribosyl)ation is required to modulate chromatin changes at c-MYC promoter during emergence from quiescence.
Mostocotto, Cassandra; Carbone, Maria Rosaria; Battistelli, Cecilia; Ciotti, Agnese; Amati, Paolo; Maione, Rossella - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. ......-...... - issn: 1932-6203 - wos: WOS:000339558100046 (11) - scopus: 2-s2.0-84904537468 (12)

11573/576384 - 2014 - Advances toward hepatic tissue engineering
Tripodi, Marco; A. M., Cozzolino; V., Costa; Conigliaro, Alice; Battistelli, Cecilia; Strippoli, Raffaele; Cicchini, Carla; Amicone, Laura - 04c Atto di convegno in rivista
paper: JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (Chichester, West Sussex, UK : John Wiley & Sons) pp. 8 (Suppl. 1): 6--8 (Suppl. 1): -38. - issn: 1932-6254 - wos: WOS:000337612600069 (0) - scopus: (0)
conference: Keynote Presentations ()

11573/572779 - 2013 - Role of DNMT3s and miR-29 family members in TGF-β mediated EMT
Battistelli, C.; Cicchini, Carla; De Nonno, V.; Ciafrè, S. A.; Amicone, Laura; Tripodi, Marco - 04a Atto di comunicazione a congresso
conference: TEMTIA 2013 The 6th International EMT Meeting (Alicante, Spain)
book: TEMTIA 2013 - The 6th International EMT Meeting - ()

11573/572784 - 2013 - Epigenetic mechanisms in TGF-β mediated EMT: role for DNMT3a and miR-29 family members.
Cicchini, Carla; De Nonno, V.; Battistelli, C.; Ciafrè, S. A.; Amicone, Laura; Tripodi, Marco - 04d Abstract in atti di convegno
conference: The ABCD (the italian association of cell biology and differentiation) Congress 2013 (Ravenna, Italy)
book: ABCD National Congress 2013 - ()

11573/572781 - 2013 - DNMT3s and miR-29 family members control EMT/MET dynamics in hepatocytes integrating the Snail/ HNF4a circuitry
De Nonno, V.; Battistelli, C.; Cozzolino, A. M.; Ciafrè, S. A.; Amicone, Laura; Cicchini, Carla; Tripodi, Marco - 04f Poster
conference: Barcelona Conferences on Epigenetics and Cancer:challenges, opportunities and perspectives. (Barcelona)
book: Barcelona Conferences on Epigenetics and Cancer:challenges, opportunities and perspectives. - ()

11573/456804 - 2012 - MyoD regulates p57kip2 expression by interacting with a distant cis-element and modifying a higher order chromatin structure
Busanello, Anna; Battistelli, Cecilia; Carbone, Maria Rosaria; Mostocotto, Cassandra; Maione, Rossella - 01a Articolo in rivista
paper: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. 8266-8275 - issn: 0305-1048 - wos: WOS:000309464300017 (30) - scopus: 2-s2.0-84866921328 (30)

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