Phd in BIOCHEMISTRY

Research: Mechanistic Insights into Antimicrobial Peptides as Novel Broad-Spectrum Drug Candidates Against Antibiotic-Resistance and Human Diseases

Education

PhD Student in Biochemistry (41st cycle) at the Department of Biochemical Sciences “Alessandro Rossi Fanelli” (CU027), Sapienza University of Rome. 11/2025 – present

Supervisor: Prof. Maria Luisa Mangoni

Master’s Degree in Chemical Sciences, curriculum “Chemistry for Life Sciences” – University of Naples “Federico II”
10/2021 – 03/2024 — Supervisor: Prof. Angela Duilio | Co-supervisor: Dr. Angela Di Somma — Final grade: 110/110 cum laude

Experimental thesis in Biochemistry: “Investigation on the molecular mechanism of Esc(1-21)-1c by functional proteomic.”

Main skills: differential and functional proteomics, LC-MS/MS, MRM analysis, molecular docking and structural modelling.

Bachelor’s Degree in Chemistry – University of Naples “Federico II”
10/2017 – 03/2021 — Supervisor: Prof. Angela Duilio — Final grade: 106/110

Experimental thesis in Biochemistry: “Functional study of the FtsZ protein on berberine derivatives.”

Main skills: recombinant protein production and purification, enzymatic assays, chromatographic techniques, MALDI-MS.

Professional Experience

Research Fellow – Department of Biochemical Sciences “A. Rossi Fanelli”, Sapienza University of Rome
01/10/2024 – 30/09/2025, Rome

Research activities within the PNRR project “Therapeutic and diagnostic innovation: new bioactive antimicrobial, targeted drug-delivery and genomic-based approach to monitor drug resistance”, funded by the European Union – Next Generation EU.

Scientific supervisor: Prof. Maria Luisa Mangoni.

Research Scholar – Istituto Pasteur Italia – Cenci Bolognetti Foundation
01/07/2024 – 30/09/2024, Rome

Research activities within the project “Small multifunctional membrane-active peptides to tackle drug-resistant respiratory and wound infections”, carried out at the Department of Biochemical Sciences “A. Rossi Fanelli”, Sapienza University of Rome.

Scientific supervisor: Prof. Maria Luisa Mangoni.

Trainee – ARPAC (Agenzia Regionale Protezione Ambientale Campania) 02/2023 – 04/2023, Naples/Pozzuoli

Activities:
-Determination of heavy metals and metalloids in real samples using ICP-OES and ICP-MS.
-Mercury analysis through thermal decomposition and atomic absorption spectrophotometry.
-Identification of micropollutants in environmental matrices by GC-MS.

Languages
Italian: native
English: B2 level