Research: Molecular dissection of Notch3-Pin1 cross-talk to overcome platinum resistance in Ovarian Cancer
PRESENT POSITION
PhD Student
Department of Molecular Medicine - Sapienza Univeristy of Rome
EDUCATION AND CAREER
2021 - today: PhD Student, Department of Molecular Medicine - Spaienza University of Rome (Italy)
2019 - 2021: Master of Study, curriculum in "Genetics and Molecular Biology" at Sapienza University of Rome (Italy) - Final Mark: 110/110 cum Laude
2016 - 2019: BSc in "Biology" at Università degli studi di Salerno (Italy) - Final Mark: 110/110 cum Laude
2011 - 2016: High School, Liceo Scientifico Francesco Severi, Salerno (Italy) - Final Mark: 100/100
CONFERENCES PARTECIPATION
•EACR 2022 CONGRESS, SEVILLE 20-23 JUNE (POSTER)
BIANCA NATIELLO, MARIA VALERIA GIULI, ANGELICA MANCUSI, ISABELLA SCREPANTI AND SAULA CHECQUOLO.
“MOLECULAR DISSECTION OF GSK3Β-WWP2 CROSSTALK TO DOWNREGULATE NOTCH3 ACTIVITY IN OVARIAN CANCER”.
•SIPMeT YOUNG SCIENTIST MEETING 2022 – “Pathophysiology of disease”, ANCONA 22-24 SEPTEMBER (e-POSTER)
BIANCA NATIELLO, MARIA VALERIA GIULI, ANGELICA MANCUSI, ISABELLA SCREPANTI AND SAULA CHECQUOLO.
“MOLECULAR DISSECTION OF GSK3Β-WWP2 CROSSTALK TO DOWNREGULATE NOTCH3 ACTIVITY IN ABCD 2023 CONGRESS, Paestum 20-21 september (poster)
•ABCD 2023 CONGRESS, Paestum 20-21 september (POSTER)
Bianca Natiello, Maria Valeria Giuli , Angelica Mancusi and Saula checquolo.
“Uncovering the molecular mechanism governing Pin1-WWP2 antagonistic interplay on Notch3 in Ovarian Cancer”.
•The Notch meeting XII 2023, Athens 1-5 october (POSTER)
Bianca Natiello, MARIA VALERIA GIULI, Angelica mancusi and Saula checquolo.
“Uncovering the molecular mechanism governing Pin1-WWP2 antagonistic
interplay on Notch3 in Ovarian Cancer”.
AWARDS AND GRANTS
(2023) Winner of the grant "Avvio alla ricerca - tipo 1" for deserving students – grant provided by “Sapienza”.
PUBBLICATIONS with IF
Giuli MV […] Natiello B et al., international J of Pharmaceutics 2023 dic s0378-5173(23)01094-3. DOI: 10.1016/j.ijpharm.2023.123672
COMPETENCES
EXPERTISE IN TECHNIQUES OF CELLULAR AND MOLECULAR BIOLOGY:
Cell culture, in vitro treatments
RNA interference
Transient transfection by liposome transefction
Lentiviral and retroviral transduction
Immunoprecipitation
Western blot
PCR, RT-PCR, qRT-PCR
Immnufluorescence assay
EXPERTISE IN IN VIVO STUDIES:
Minimally invasive training procedures withouth anaesthesia- mice