Name and surname:
Bianca Maria Scicchitano
Place and date of birth Rome, 23/06/1966
Citizen Italian
e-mail: biancamaria.scicchitano@unicatt.it; bianca.scicchitano@gmail.com
Scopus Author ID:7801352865
ORCID ID: https://orcid.org/0000-0002-9599-6642
Current Position: Associate Professor, Faculty of Medicine and Surgery A.Gemelli, Department of Life Sciences and Public Health, Section of Histology and Embryology, Catholic University of Sacred Heart, Rome
Education/training
1985 High School diploma, Liceo Giulio Cesare di Roma.
1992 Degree in Biological Sciences, the University of Rome "La Sapienza", Italy
1998 Ph.D. in Morphogenetic and Cytological Sciences, Section of Histology and
Medical Embryology, Department of Anatomical, Histological, Medico-legal and Locomotor Apparatus Sciences, Faculty of Medicine and Surgery, Sapienza
University of Rome, Italy.
Positions
1997-1999 Research Fellow in Cutaneous Biology Research Center, Mass. General Hospital-East, Harvard Medical School, Boston, USA.
2000-2007 Senior post-Doc at the Section of Histology and Medical Embryology,
Department of Anatomical, Histological, Medico-legal Sciences and of the Locomotor Apparatus, Faculty of Medicine and Surgery, Sapienza University of
Rome, Italy
2009 - 2012 Head of the Real-Time PCR Laboratory in the Section of Histology and Medical Embryology, Department of Anatomical, Histological, Medico-legal
Sciences and of the Locomotor Apparatus, Faculty of Medicine and Surgery, Sapienza University of Rome, Italy.
2007-2011 Research Fellow - Project entitled "Signaling mechanisms in skeletal muscle catabolism" - at the Italian Space Agency, Via di Villa Grazioli 23, 00198 Rome.
2009-2011 Senior post-Doc at the Section of Histology and Medical Embryology, Department of Anatomical, Histological, Medico-legal Sciences and of the Locomotor Apparatus, Faculty of Medicine and Surgery, Sapienza University of
Rome, Italy
2011-2012 Research Fellow - Project entitled “Stem cell based approaches to muscle diseases” - at the Section of Histology and Medical Embryology, Department of
Anatomical, Histological, Medico-legal Sciences and of the Locomotor Apparatus, Faculty of Medicine and Surgery, Sapienza University of Rome, Italy.
2012-2017 Researcher Assistant (RTDA) Institute of Histology, Faculty of Medicine -Catholic University of the Sacred Heart, Largo Francesco Vito, 1 00168 Rome Italy.
2012-2014 Member of the Faculty Commission for the management of the study plan and the start of teaching activities of the Degree Course in Medicine and Surgery, Faculty of Medicine and Surgery “A. Gemelli”, Catholic University of the Sacred Heart of Rome.
From 2017- current Member of the Academic Committee of PhD program in Morphogenesis &
Tissue Engineering - Section of Histology and Medical Embryology, Department of Anatomical, Histological, Medico-legal Sciences and of the Locomotor Apparatus, Faculty of Medicine and Surgery, Sapienza University of
Rome, Italy.
2018-2021 Researcher Assistant (RTDB) Institute of Histology - Catholic University of the Sacred Heart, Largo Francesco Vito, 1 00168 Rome, Italy
From 2018 - 2022 Coordinator of the 1st year - Master Degree Course in Orthopedic Techniques, Medical School, Catholic University of the Sacred Heart, Largo Francesco Vito, 1 00168 Rome, Italy
From 2018 - 2022 Coordinator of Integrated Course of Biomedical Sciences, Master Degree Course in Orthopedic Techniques Medical School, Catholic University of the Sacred Heart, Largo Francesco Vito, 1 00168 Rome, Italy.
From 2018 - current Member of Joint Committee (AVA) - Master Degree Course in Orthopedic Techniques, Medical School, Catholic University of the Sacred Heart, Largo Francesco Vito, 1 00168 Rome, Italy.
From 2021 - current Member of Joint Committee (AVA) - Master Degree Course in Biotechnology for Personalized Medicine, Faculty of Medicine and Surgery “A. Gemelli”, Catholic University of the Sacred Heart of Rome.
From 2021 - current Coordinator of Integrated Course "Molecular Bases of Disease" in the Master's Degree Course in Biotechnology for Personalized Medicine, Faculty of Medicine and Surgery "A. Gemelli”, Catholic University of the Sacred Heart of Rome.
From 2021 - current Coordinator of Integrated Course of Organic and Functional Systems II, 2° Year, Master's Degree Course in Medicine and Surgery in English language.
From 2022 - current Coordinator of 2° year, Master's Degree Course in Medicine and Surgery in English language.
From 2016 - current Member of the Supervisory Commission for the admission exams to the Single Cycle Degree Course in Medicine and Surgery “A. Gemelli”, Catholic University of the Sacred Heart of Rome.
2018-2019 Member of the Supervisory Commissions for the admission tests to the Degree Courses in Cosmetological Sciences and to the Degree Courses in Health Professions Faculty of Medicine and Surgery “A. Gemelli”, Catholic University of the Sacred Heart of Rome.
2019-2020 President of the Supervisory Commissions for the admission tests to the Degree Courses in Cosmetological Sciences and Technologies and to the Degree Courses in Health Professions Faculty of Medicine and Surgery “A. Gemelli”, Catholic University of the Sacred Heart of Rome.
2020 National Scientific Habilitation 2018 Associate Professor 05/H2 - HISTOLOGY
2023 National Scientific Habilitation 2023 Full Professor 05/H2 - HISTOLOGY
Affiliation to academies of recognized prestige
From 2014 - current Interuniversity Institute of Myology (IIM)
From 2015 - current Ordinary member of the Italian Society of Anatomy and Histology
Awards for scientific activity
2021 High quality publications award, 2021 Catholic University of the Sacred Heart
Teaching activity
From 2023 - current Professor of Histology – Lectures- School of Medicine, Catholic
University of the Sacred Heart, Rome, Italy
From 2012 - current Professor of Histology – Practical training- School of Medicine, Catholic
University of the Sacred Heart, Rome, Italy
2013 -2019 Professor of Histology – Practical training, 1° e 2° Year, Medicine and Surgery (English language), Catholic University of the Sacred Heart:
Molecules and Cells:
• Histology Techniques
• Epithelial Tissue
• Connective Tissue
• Blood
Organic and Functional Systems III
• Reproductive System
• Nervous System
From 2013 - current Professor of Histology Practicals, 1° e 2° Year, Medicine and Surgery (English language), Catholic University of the Sacred Heart:
Organic and Functional Systems I
• Skeletal Muscle System
• Heart
Organic and Functional Systems II
• Vascular - Lymphatic and Endocrine Systems
• Digestive System
• Respiratory System
• Urinary System
From 2017 - current Professor in the Degree Course “Nursing and Midwifery Science” – Catholic University of the Sacred Heart, Rome, Italy.
From 2017 - current Professor of Histology in the Degree Course “Orthopedic techniques” Catholic University of the Sacred Heart, Rome, Italy.
From 2017 - current Professor of Histology in the Degree Course “Cosmetology Sciences” Catholic University of the Sacred Heart Rome, Italy.
From 2018 - current Professor of Histology “Bone and Muscles” 1st year, Medicine and Surgery
(english language), Catholic University of the Sacred Heart, Rome, Italy.
From 2020- Current Professor of Histology and Embryology of Organic and Functional Systems II Course:
• Vascular - Lymphatic
• Respiratory System
From 2019 - Current Professor of "Stem cells and disease mechanisms” - Degree Course in Biotechnology Sciences, Catholic University of the Sacred Heart, Rome, Italy.
From 2023 - Current Reference Teacher Master degree in Medicine And Surgery ROMA-Università Cattolica del Sacro Cuore,
Funded Projects
2013-2015 Nutritional strategies to counteract the loss of muscle mass and function characteristic of senescent muscles 2015. Progetto di Ateneo- Linea D.3.2- Anno 2013, Catholic University of he Sacred Heart, Rome, Italy. Financing Euro 25,000.
2015-2017 Effects of dietary supplementation on epigenic regulation of sarcopenia.
Progetto di Ateneo - Linea D.3.2- Anno 2015, Catholic University of the
Sacred Heart, Rome, Italy. Financing Euro 30,000.
2018 Progetto di Ateneo LINEA D.3.1 2018
2019 Progetto di Ateneo LINEA D.3.1 2019
2021 Progetto di Ateneo LINEA D.3.1 2021
2021 Progetto di Ateneo LINEA D.1 2021
2023 Progetto di Ateneo LINEA D.1 2023
2023 Progetto di Ateneo LINEA D.3.1 2023
Editorial Activity
From 2018 - current Expert reviewer several international journals such as Antioxidants, Frontiers in Physiology, European Journal of Translational Myology, Journal Acta Medica Academica.
2018 Participation in the drafting and publication of the volume "Fondamenti di istologia e cenni di embriologia" Casa Editrice Piccin
2019 Curatore dell'opera: Moore- Lo sviluppo prenatale dell’uomo – XI Edizione
From 2019 - current Member of the Editorial Board of the following journals: Antioxidants, European Journal of Translational Myology.
2021 Guest Editor for the Special Issue “The Role of Skeletal Muscle in Neuromuscular Diseases: From Cellular and Molecular Players to Therapeutic Interventions” in the journal Cells.
2021 Guest Editor for the Special Issue "Musculoskeletal Aging and Sarcopenia in the Elderly" in the journal Geriatrics
PUBBLICATIONS
H-index 23 Citations 1,453 WoS
H-index 21 Citations 1,409 Scopus
H-index 26 Citations 2209 Google Scholar
1. Fard D, Barbiera A, Dobrowolny G, Tamagnone L, Scicchitano BM.
Semaphorins: Missing Signals in Age-dependent Alteration of Neuromuscular Junctions and Skeletal Muscle Regeneration.
Aging Dis. 2023 Sep 3. doi: 10.14336/AD.2023.0801. Online ahead of print.
2. Gesualdi L, Berardini M, Scicchitano BM, Castaldo C, Bizzarri M, Filippini A, Riccioli A, Schiraldi C, Ferranti F, Liguoro D, Mancini R, Ricci G, Catizone A.
ERK Signaling Pathway Is Constitutively Active in NT2D1 Non-Seminoma Cells and Its Inhibition Impairs Basal and HGF-Activated Cell Proliferation.
Biomedicines. 2023 Jul 4;11(7):1894. doi: 10.3390/biomedicines11071894.
3. Fard D, Testa E, Panzeri V, Rizzolio S, Bianchetti G, Napolitano V, Masciarelli S, Fazi F, Maulucci G, Scicchitano BM, Sette C, Viscomi MT, Tamagnone L. SEMA6C: a novel adhesion-independent FAK and YAP activator, required for cancer cell viability and growth. Cell Mol Life Sci. 2023 Mar 31;80(4):111. doi: 10.1007/s00018-023-04756-1
4. Barbiera A, Sorrentino S, Fard D, Lepore E, Sica G, Dobrowolny G, Tamagnone L, Scicchitano BM. Taurine Administration Counteracts Aging-Associated Impingement of Skeletal Muscle Regeneration by Reducing Inflammation and Oxidative Stress. Antioxidants (Basel). 2022 May 21;11(5):1016. doi: 10.3390/antiox11051016.
5. Dobrowolny G, Scicchitano BM. The Role of Skeletal Muscle in Neuromuscular Diseases: From Cellular and Molecular Players to Therapeutic Interventions. Cells. 2022 Apr 3;11(7):1207. doi: 10.3390/cells11071207.
6. Scicchitano BM, Bouchè M, Nervi C, Coletti D. A tribute to Professor Sergio Adamo, Full Professor of Histology and Embryology at Sapienza University, Rome. Eur J Transl Myol. 2022 Mar 3;32(1). doi: 10.4081/ejtm.2022.10434. PMID: 35244364.
7. Gesualdi, L; Leonetti, E; Cucina, A; Scicchitano, BM; Sorrentino, S; Tarsitano, MG; Isidori, A; Bizzarri, M; Filippini, A; Riccioli, A; Cammarota, M; Gigantino, V; Ricci, G; Catizone, A. Re: The PI3K/AKT Pathway Is Activated by HGF in NT2D1 Non-Seminoma Cells and Has a Role in the Modulation of Their Malignant Behavior Editorial Comment
Mar 2022 | JOURNAL OF UROLOGY 207 (3), pp.738-738.
8. Casola I, Scicchitano BM, Lepore E, Mandillo S, Golini E, Nicoletti C, Barberi L, Dobrowolny G, Musarò A. Circulating myomiRs in Muscle Denervation: From Surgical to ALS Pathological Condition. Cells. 2021 Aug 10;10(8):2043. doi: 10.3390/cells10082043. PMID: 34440812; PMCID: PMC8393851.
9. Pelosi L, Berardinelli MG, Forcina L, Ascenzi F, Rizzuto E, Sandri M, De Benedetti F, Scicchitano BM, Musarò A. Sustained Systemic Levels of IL-6 Impinge Early Muscle Growth and Induce Muscle Atrophy and Wasting in Adulthood. Cells. 2021 Jul 18;10(7):1816. doi: 10.3390/cells10071816. PMID: 34359985; PMCID: PMC8306542.
10. Dobrowolny G, Barbiera A, Sica G, Scicchitano BM. Age-Related Alterations at Neuromuscular Junction: Role of Oxidative Stress and Epigenetic Modifications. Cells. 2021 May 24;10(6):1307. doi: 10.3390/cells10061307. PMID: 34074012; PMCID: PMC8225025.
11. Dobrowolny G, Martone J, Lepore E, Casola I, Petrucci A, Inghilleri M, Morlando M, Colantoni A, Scicchitano BM, Calvo A, Bisogni G, Chiò A, Sabatelli M, Bozzoni I, Musarò A. A longitudinal study defined circulating microRNAs as reliable biomarkers for disease prognosis and progression in ALS human patients. Cell Death Discov. 2021 Jan 11;7(1):4.
12. Barbiera A, Sorrentino S, Lepore E, Carfì A, Sica G, Dobrowolny G, Scicchitano BM. Taurine Attenuates Catabolic Processes Related to the Onset of Sarcopenia. Int J Mol Sci. 2020 Nov 23;21(22):8865. doi: 10.3390/ijms21228865.
13. Gesualdi L, Leonetti E, Cucina A, Scicchitano BM, Sorrentino S, Tarsitano MG, Isidori A, Bizzarri M, Filippini A, Riccioli A, Cammarota M, Gigantino V, Ricci G, Catizone A. The PI3K/AKT Pathway Is Activated by HGF in NT2D1 Non-Seminoma Cells and Has a Role in the Modulation of Their Malignant Behavior. Int J Mol Sci. 2020 Nov 17;21(22):8669. doi: 10.3390/ijms21228669.
14. Barbiera A, Pelosi L, Sica G, Scicchitano BM. Nutrition and microRNAs: Novel Insights to Fight Sarcopenia. Antioxidants (Basel). 2020 Oct 2;9(10):951. doi: 10.3390/antiox9100951.
15. Colapietro A, Gravina GL, Petragnano F, Fasciani I, Scicchitano BM. Antitumorigenic Effects of Inhibiting Ephrin Receptor Kinase Signaling by GLPG1790 against Colorectal Cancer Cell Lines In Vitro and In Vivo. J Oncol. 2020;2020:9342732. Published 2020 Feb 27. doi:10.1155/2020/9342732.
16. Forcina L, Miano C, Scicchitano BM, et al. Increased Circulating Levels of Interleukin-6 Affect the Redox Balance in Skeletal Muscle. Oxid Med Cell Longev. 2019;2019:3018584. Published 2019 Nov 16. doi:10.1155/2019/3018584.
17. Sorrentino S, Barbiera A, Proietti G, Sica G, Adamo S, Scicchitano BM. Inhibition of Phosphoinositide 3-Kinase/Protein Kinase B Signaling Hampers the Vasopressin-dependent Stimulation of Myogenic Differentiation. Int J Mol Sci. 2019;20(17):4188. Published 2019 Aug 27. doi:10.3390/ijms20174188.
18. Marampon F, Di Nisio V, Pietrantoni I, Petragnano F, Fasciani I, Scicchitano BM, et al. Pro-differentiating and radiosensitizing effects of inhibiting HDACs by PXD-101 (Belinostat) in in vitro and in vivo models of human rhabdomyosarcoma cell lines. Cancer Lett. 2019;461:90-101.
19. Musarò A, Scicchitano BM. Counteracting sarcopenia: the role of IGF-1 isoforms. Aging (Albany NY). 2019;11(11):3410-3411. doi:10.18632/aging.102027.
20. D'Alessio A, Proietti G, Sica G, Scicchitano BM. Pathological and Molecular Features of Glioblastoma and Its Peritumoral Tissue. Cancers (Basel). 2019;11(4):469. Published 2019 Apr 3. doi:10.3390/cancers11040469.
21. Ascenzi F, Barberi L, Dobrowolny G, Villa Nova Bacurau A, Nicoletti C, Rizzuto E, Rosenthal N, Scicchitano BM, Musarò A. Effects of IGF-1 isoforms on muscle growth and sarcopenia. Aging Cell. 2019;18(3):e12954. doi:10.1111/acel.12954.
22. Forcina L, Miano C, Scicchitano BM, Musarò A. Signals from the Niche: Insights into the Role of IGF-1 and IL-6 in Modulating Skeletal Muscle Fibrosis. Cells. 2019;8(3):232. Published 2019 Mar 11. doi:10.3390/cells8030232.
23. Sajer S, Guardiero GS, Scicchitano BM. Myokines in Home-Based Functional Electrical Stimulation-Induced Recovery of Skeletal Muscle in Elderly and Permanent Denervation. Eur J Transl Myol. 2018;28(4):7905. Published 2018 Nov 16. doi:10.4081/ejtm.2018.7905.
24. Scicchitano BM, Sorrentino S, Proietti G, et al. Levetiracetam enhances the temozolomide effect on glioblastoma stem cell proliferation and apoptosis. Cancer Cell Int. 2018;18:136. Published 2018 Sep 10. doi:10.1186/s12935-018-0626-8.
25. Scicchitano BM, Dobrowolny G, Sica G, Musarò A. Molecular Insights into Muscle Homeostasis, Atrophy and Wasting. Curr Genomics. 2018;19(5):356-369. doi:10.2174/1389202919666180101153911.
26. Dobrowolny G, Lepore E, Martini M, Barberi L, Nunn A, Scicchitano BM, Musarò A.. Metabolic Changes Associated With Muscle Expression of SOD1G93A. Front Physiol. 2018;9:831. Published 2018 Jul 10. doi:10.3389/fphys.2018.0083.
27. Dobrowolny G, Martini M, Scicchitano BM, et al. Muscle Expression of SOD1G93A Triggers the Dismantlement of Neuromuscular Junction via PKC-Theta. Antioxid Redox Signal. 2018;28(12):1105-1119. doi:10.1089/ars.2017.7054.
28. Scicchitano BM, Pelosi L, Sica G, Musarò A. The physiopathologic role of oxidative stress in skeletal muscle. Mech Ageing Dev. 2018;170:37-44. doi:10.1016/j.mad.2017.08.009.
29. Scicchitano BM, Sica G. The Beneficial Effects of Taurine to Counteract Sarcopenia. Curr Protein Pept Sci. 2018;19(7):673-680. doi:10.2174/1389203718666161122113609.
30. Pelosi L, Forcina L, Nicoletti C, Scicchitano BM, Musarò A. Increased Circulating Levels of Interleukin-6 Induce Perturbation in Redox-Regulated Signaling Cascades in Muscle of Dystrophic Mice. Oxid Med Cell Longev. 2017;2017:1987218. doi:10.1155/2017/1987218.
31. Sciandra F, Scicchitano BM, Signorino G, et al. Evaluation of the effect of a floxed Neo cassette within the dystroglycan (Dag1) gene. BMC Res Notes. 2017;10(1):601. Published 2017 Nov 21. doi:10.1186/s13104-017-2926-9
32. Scicchitano BM, Sica G, Musarò A. Stem Cells and Tissue Niche: Two Faces of the Same Coin of Muscle Regeneration. Eur J Transl Myol. 2016;26(4):6125. Published 2016 Nov 25. doi:10.4081/ejtm.2016.6125
33. Barberi L, Scicchitano BM, Musaro A. Molecular and Cellular Mechanisms of Muscle Aging and Sarcopenia and Effects of Electrical Stimulation in Seniors. Eur J Transl Myol. 2015;25(4):231-236. Published 2015 Aug 25. doi:10.4081/ejtm.2015.5227
34. Sica, G; Lama, G; Colabianchi, A; D'Alessio, A; Proietti, G; Angelucci, C; Scicchitano, BM; Mangiola, A; Binda, E; Vescovi, A; Maira, G. CHARACTERIZATION OF CANCER STEM CELLS DERIVED FROM GLIOBLASTOMA AND PERITUMOR TISSUE. Oct 2014 | ANTICANCER RESEARCH 34 (10), pp.6164-6165.
35. Scicchitano BM, Faraldi M, Musarò A. The Proteolytic Systems of Muscle Wasting. Recent Adv DNA Gene Seq. 2015;9(1):26-35. doi:10.2174/2352092209999150911121502.
36. Costa A, Rossi E, Scicchitano BM, Coletti D, Moresi V, Adamo S. Neurohypophyseal Hormones: Novel Actors of Striated Muscle Development and Homeostasis. Eur J Transl Myol. 2014;24(3):3790. Published 2014 Sep 22. doi:10.4081/ejtm.2014.3790.
37. Costa A, Toschi A, Murfuni I, Pelosi L, Sica G, Adamo S, Scicchitano BM.. Local overexpression of V1a-vasopressin receptor enhances regeneration in tumor necrosis factor-induced muscle atrophy. Biomed Res Int. 2014;2014:235426. doi:10.1155/2014/235426.
38. Barberi L, Scicchitano BM, De Rossi M, et al. Age-dependent alteration in muscle regeneration: the critical role of tissue niche. Biogerontology. 2013;14(3):273-292. doi:10.1007/s10522-013-9429-4.
39. Toschi A, Severi A, Coletti D, Catizone A, Musarò A, Molinaro M, Nervi C, Adamo S, Scicchitano BM. Skeletal muscle regeneration in mice is stimulated by local overexpression of V1a-vasopressin receptor. Mol Endocrinol. 2011;25(9):1661-1673. doi:10.1210/me.2011-1049.
40. Scicchitano BM, Rizzuto E, Musarò A. Counteracting muscle wasting in aging and neuromuscular diseases: the critical role of IGF-1. Aging (Albany NY). 2009;1(5):451-457. Published 2009 May 13. doi:10.18632/aging.100050.
41. Berardi E, Aulino P, Murfuni I, Toschi A, Padula F, Scicchitano BM, Coletti D, Adamo S.. Skeletal muscle is enriched in hematopoietic stem cells and not inflammatory cells in cachectic mice. Neurol Res. 2008;30(2):160-169. doi:10.1179/174313208X281046.
42. Moresi V, Pristerà A, Scicchitano BM, et al. Tumor necrosis factor-alpha inhibition of skeletal muscle regeneration is mediated by a caspase-dependent stem cell response. Stem Cells. 2008;26(4):997-1008. doi:10.1634/stemcells.2007-0493.
43. Weiner L, Han R, Scicchitano BM, et al. Dedicated epithelial recipient cells determine pigmentation patterns. Cell. 2007;130(5):932-942. doi:10.1016/j.cell.2007.07.024.
44. Musarò A, Giacinti C, Pelosi L, Dobrowolny G, Barberi L, Nardis C, Coletti D, Scicchitano BM, Adamo S, Molinaro M. Stem cell-mediated muscle regeneration and repair in aging and neuromuscular diseases. Eur J Histochem. 2007;51 Suppl 1:35-43.
45. Scicchitano BM, Spath L, Musarò A, et al. Vasopressin-dependent myogenic cell differentiation is mediated by both Ca2+/calmodulin-dependent kinase and calcineurin pathways. Mol Biol Cell. 2005;16(8):3632-3641. doi:10.1091/mbc.e05-01-0055.
46. Weiner, L; Han, R; Scicchitano, BM; Lee, D (Lee, D) ; Brissette, JL. The Foxn1 transcription factor converts epithelial cells into targets for pigmentation. 65th Annual Meeting of the Society-for-Investigative-Dermatology. Mar 2004 | JOURNAL OF INVESTIGATIVE DERMATOLOGY 122 (3), pp.A154-A154.
47. Scicchitano BM, Spath L, Musarò A, Molinaro M, Adamo S, Nervi C. AVP induces myogenesis through the transcriptional activation of the myocyte enhancer factor 2. Mol Endocrinol. 2002;16(6):1407-1416. doi:10.1210/mend.16.6.0854.
48. Minotti S, Scicchitano BM, Nervi C, et al. Vasopressin and insulin-like growth factors synergistically induce myogenesis in serum-free medium. Cell Growth Differ. 1998;9(2):155-163.
49. Benedetti L, Levin AA, Scicchitano BM, et al. Characterization of the retinoid binding properties of the major fusion products present in acute promyelocytic leukemia cells. Blood. 1997;90(3):1175-1185.
50. Benedetti L, Grignani F, Scicchitano BM, et al. Retinoid-induced differentiation of acute promyelocytic leukemia involves PML-RARalpha-mediated increase of type II transglutaminase. Blood. 1996;87(5):1939-1950.
Rome April 24, 2023 Signature