Dottorato in BIOLOGIA UMANA E GENETICA MEDICA

Ricerca: Cell-autonomous and non Cell autonomous responses to replication stress in normal and tumor cells

01/11/2024 – Present PhD Student in Human Biology and Medical Genetics Project: “Cell-autonomous and non Cell autonomous responses to replication stress in normal and tumor cells” Istituto Superiore di Sanità & Sapienza University of Rome, Italy WORKING EXPERIENCE INTERNSHIP 01/04/2024 – 31/10/2024 Research Fellowship for Graduates Environment and Health Department, Istituto Superiore di Sanità, Rome Research activity focused on DNA replication mechanisms and the role of the WRN protein in maintaining genome stability. 09/2022 – 01/2024 Master’s Thesis Internship Mechanisms, Biomarkers and Models Unit, DAMSA Department Istituto Superiore di Sanità, Rome Project: “Role of WRN phosphorylation in the regulation of DSB repair in S-phase” 08/11/2019 – 11/12/2019 Training Internship Istituto Zooprofilattico Sperimentale della Sicilia EDUCATION AND TRAINING 17/01/2024 Master’s Degree in Genetics and Molecular Biology (LM-6) Sapienza University of Rome, Italy Thesis: “Functional correlation studies between the WRN protein and the SAMHD1 protein” 19/10/2022 Bachelor of Music – Piano (First Level Academic Diploma) Conservatorio “Arcangelo Corelli”, Messina 23/03/2021 Bachelor’s Degree in Biological Sciences University of Messina, Italy Thesis: “BRCA1 and BRCA2 in tumor development” 02/06/2017 High School Diploma – Classical Studies Liceo Classico “Luigi Valli”, Barcellona Pozzo di Gotto (ME) LICENSES AND CERTIFICATIONS 2024 Professional License: Biologist Sapienza University of Rome Registered in the Order of Biologists Lazio–Abruzzo (02/2025) Registration No.: AA_101039 SEMINARS, CONFERENCES AND TRAINING ACTIVITIES 2025 • 11/09/2025 — Seminar From Genomics to Diabetes Precision Medicine? Speaker: Philippe Froguel – Sapienza University of Rome • 22/05/2025 — Seminar SMARCAL1 as a Dual Regulator of Innate Signaling and PD-L1 Expression Promoting Tumor Immune Evasion Speaker: Giuseppe Leuzzi – Sapienza University of Rome • 05/05/2025 — Seminar The Genetics of Centenarians Informs Aging Research: Insights from SIRT6 Speaker: Manlio Vinciguerra – Sapienza University of Rome • 17/04/2025 — Seminar Ten Years of Reprogramming: From Transcriptional Trajectories to Organoids Speaker: Davide Cacchiarelli – Sapienza University of Rome • 11/03/2025 — Seminar Metamorphosis of Prenatal Genetic Diagnosis: A Journey Through Science and the Future Speaker: Antonio Novelli – Sapienza University of Rome • 24/11/2025 — Workshop Young Researchers and Oncology Research: Tumor Microenvironment and Immunity Istituto Superiore di Sanità – Department of Oncology and Molecular Medicine 2024 • 02/12/2024 — Conference Hijacking the “Good” Pathways: Cancer, Immunity and Therapeutic Approaches Speakers: Simon Bucazki, Veronica Veschi, Ilaria Malanchi, Alessandra Boletta, Barbara Stecca, Michele Ardolino, Paola Arimondo, Luca Scorrano, Antonella Sistigu, Claudio Mauro, Angrisani, Novelli, Sangiolo Sapienza University of Rome • Technical consulting activity for a molecular cloning kit – Aurogene • 02/02/2024 — Course Getting Started with Genomics: Next Generation Sequencing Essentials – Novogene • 25–27/01/2024 — Course Genomics: Advanced Technologies – FISV, Milan 2023 • 28/11/2023 — Conference Bridging Immunity to Cancer – Istituto Superiore di Sanità, Rome • ISS Conferences (Rome, 2023): o In vitro digestion of nanomaterials for OECD Guidance Document (07/03/2023) o Self-care for Healthcare Professionals (03/03/2023) 2019 • 08/07/2019 — Course Workplace Safety and Laboratory Safety – University of Messina