Dottorato in EXPERIMENTAL MEDICINE

Dr. Beatrice Simeone is a Specialist Physician in Cardiovascular Diseases and a PhD candidate of the 39th cycle of the PhD Program in Experimental Medicine at Sapienza University of Rome, where she conducts her research under the supervision of Professor Sebastiano Sciarretta, her current academic tutor and mentor. Her clinical and scientific activity is focused on clinical, translational, and molecular cardiology, with particular interest in heart failure, cardiomyopathies, cardiac amyloidosis, prognostic stratification, and the biological mechanisms involved in the progression of cardiovascular diseases, with a specific focus on autophagy processes. She is currently working as a staff cardiologist at the Cardiac Intensive Care Unit (UTIC)/University Cardiology Unit of ICOT Hospital in Latina, where she is involved in the management of cardiac patients in both inpatient settings, including intensive care, and outpatient clinics. Her experience particularly includes the diagnosis, treatment, and follow-up of patients with heart failure, cardiomyopathies, arrhythmias, coronary syndromes, pericarditis, and myocarditis, as well as clinical activity in specialized outpatient clinics dedicated to heart failure, cardiomyopathies, cardio-oncology, and cardiac amyloidosis. She also has advanced expertise in cardiovascular imaging and in the main non-invasive and semi-invasive diagnostic techniques, including advanced echocardiography, transesophageal echocardiography, stress echocardiography, Holter ECG monitoring, and provocative testing. After graduating with honors in Medicine and Surgery from Sapienza University of Rome, she completed her specialization with honors in Cardiovascular Diseases at the University of Perugia and obtained a second-level Master’s degree in Cardiac Intensive Care from the University of Florence, consolidating a training path focused on the management of complex and critically ill cardiac patients. As part of her PhD, since 2026 she has been carrying out a research period at the Karolinska Institutet in Stockholm as a Visiting PhD Student, under the supervision of Professor Gianluigi Savarese, in a highly advanced clinical research environment focused on heart failure. This experience is particularly centered on the clinical and prognostic phenotyping of patients with heart failure, the analysis of large cardiovascular registries, including the Swedish Heart Failure Registry, and the application of big data approaches to identify clinical profiles, disease trajectories, and potential determinants of therapeutic response. This research activity complements her translational work, with the aim of linking molecular mechanisms—including those related to autophagy—to their clinical and prognostic implications in patients with complex cardiovascular diseases. Her scientific activity is documented by publications in international peer-reviewed journals and participation in national and international conferences, also as a speaker, particularly in the fields of heart failure, cardiovascular imaging, cardiac amyloidosis, and translational research in cardiology.