AZADEH MONTASERI

Dottoranda

ciclo: XXXVI
email: montaseri.1978235@studenti.uniroma1.it
telefono: 0649766582
edificio: RM 004 Palazzina E (Ex casa del Fante) Via Antonio Scarpa 14/16
stanza: 5

supervisore: Prof. Antonio Filippini

Ricerca: Gli effetti degli inibitori di TPC2 sulla via dell'autofagia durante l'osteoblastogenesi e l'osteoclastogenesi

L'autofagia è coinvolta nell'osteogenesi e il suo disturbo è associato all'osteoporosi. Durante la differenziazione degli osteoclasti, l'espressione dei canali a due pori di tipo 2 (TPC2) aumenta e ci sono alcune prove che il silenziamento di TPC2 possa inibire l'espressione dei marcatori di autofagia. Anche un'altra famiglia di proteine chiamata galectine è coinvolta nell'osteogenesi e alcuni studi hanno riscontrato la cooperazione tra ULK1 e galectine durante la differenziazione delle cellule ossee. Sulla base di queste informazioni, gli obiettivi di questo studio sono: 1. Valutare gli effetti degli inibitori di TPC2 sulla via dell'autofagia nell'osteogenesi, 2. Comprendere la correlazione tra galectina e TPC2 durante l'osteogenesi, 3. Studio dei parametri ossei, TPC2 e l'espressione della galectina in topi beclin1 knockout.

Produzione scientifica

11573/1669745 - 2023 - Extracellular vesicles of immune cells; immunomodulatory impacts and therapeutic potentials (01a Articolo in rivista)
AZADEH MONTASERI
11573/1463717 - 2020 - The role of autophagy in osteoclast differentiation and bone resorption function (01g Articolo di rassegna (Review))
AZADEH MONTASERI, Claudia GIAMPIETRI, ANNA RICCIOLI, Antonio FILIPPINI
11573/1560123 - 2020 - Preparation and characterization of novel anti-inflammatory biological agents based on piroxicam-loaded poly-ε-caprolactone nano-particles for sustained NSAID delivery (01a Articolo in rivista)
AZADEH MONTASERI
11573/1558816 - 2020 - Differential biological behavior of fibroblasts and endothelial cells under aloe vera gel culturing (01a Articolo in rivista)
AZADEH MONTASERI
11573/1559729 - 2019 - An overview of advanced biocompatible and biomimetic materials for creation of replacement structures in the musculoskeletal systems: focusing on cartilage tissue engineering (01g Articolo di rassegna (Review))
AZADEH MONTASERI
11573/1559911 - 2019 - Cytotoxicity of universal dental adhesive systems: assessment in vitro assays on human gingival fibroblasts (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560127 - 2019 - Quercetin alleviates high glucose-induced damage on human umbilical vein endothelial cells by promoting autophagy (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560357 - 2019 - Biological effects of resin monomers on oral cell populations: descriptive analysis of literature (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560131 - 2018 - Synthesis and in vitro evaluation of thermosensitive hydrogel scaffolds based on (PNIPAAm-PCL-PEG-PCL-PNIPAAm)/Gelatin and (PCL-PEG-PCL)/Gelatin for use in cartilage tissue engineering (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560129 - 2018 - Mummy material can promote differentiation of adipose derived stem cells into osteoblast through enhancement of bone specific transcription factors expression (01a Articolo in rivista)
AZADEH MONTASERI
11573/1558941 - 2018 - Recent advances on biomedical applications of scaffolds in wound healing and dermal tissue engineering (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560141 - 2018 - Mummy prevents IL-1β-Induced inflammatory responses and cartilage matrix degradation via inhibition of NF-κB subunits gene expression in pellet culture system (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560125 - 2018 - Silibinin protects human endothelial cells from high glucose-induced injury by enhancing autophagic response (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560281 - 2017 - Rapamycin inhibits oxidative/nitrosative stress and enhances angiogenesis in high glucose-treated human umbilical vein endothelial cells: role of autophagy (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560135 - 2017 - Effect of hydroxychloroquine on oxidative/nitrosative status and angiogenesis in endothelial cells under high glucose condition (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560286 - 2017 - Conditioned medium of Wharton's jelly derived stem cells can enhance the cartilage specific genes expression by chondrocytes in monolayer and mass culture systems (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560321 - 2016 - Effects of continuous wave and fractionated diode laser on human fibroblast cancer and dermal normal cells by zinc phthalocyanine in photodynamic therapy: a comparative study (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560143 - 2016 - Impact of prunus cerasus on PGR and HAS2 in cumulus cells and fertility outcome (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560292 - 2015 - Evaluation of the melatonin and oxidative stress markers level in serum of fertile and infertile women (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560300 - 2013 - Serum Levels of Melatonin and Oxidative Stress Markers and Correlation between Them in Infertile Men (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560328 - 2011 - Curcumin modulates nuclear factor κB (nf-κB)-mediated inflammation in human tenocytes in vitro: Role of the phosphatidylinositol 3-kinase/Akt pathway (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560311 - 2011 - Study of Foeniculum vulgare Effect on Folliculogenesis in Female Mice (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560352 - 2011 - IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: Involvement of Src/PI-3k/AKT pathway (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560348 - 2010 - Recurrent Intracranial Haemangiopericytoma compatible to Synovial Sarcoma (01a Articolo in rivista)
AZADEH MONTASERI
11573/1560339 - 2009 - Letrozole stimulates the growth of human endometrial explants cultured in three-dimensional fibrin matrix (01a Articolo in rivista)
AZADEH MONTASERI