11573/1714682 - 2024 -
Pharmacological activation of SIRT3 modulates the response of cancer cells to acidic ph Aventaggiato, Michele; Arcangeli, Tania; Vernucci, Enza; Barreca, Federica; Sansone, Luigi; Pellegrini, Laura; Pontemezzo, Elena; Valente, Sergio; Fioravanti, Rossella; Antonio Russo, Matteo; Mai, Antonello; Tafani, Marco - 01a Articolo in rivista
paper: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. - - issn: 1424-8247 - wos: WOS:001256759700001 (0) - scopus: 2-s2.0-85197858664 (0)
11573/1717112 - 2024 -
HDAC3 genetic and pharmacologic inhibition radiosensitizes fusion positive rhabdomyosarcoma by promoting DNA double-strand breaks Cassandri, Matteo; Porrazzo, Antonella; Pomella, Silvia; Noce, Beatrice; Zwergel, Clemens; Aiello, Francesca Antonella; Vulcano, Francesca; Milazzo, Luisa; Camero, Simona; Pajalunga, Deborah; Spada, Massimo; Manzi, Valeria; Gravina, Giovanni Luca; Codenotti, Silvia; Piccione, Michela; Tomaciello, Miriam; Signore, Michele; Barillari, Giovanni; Marchese, Cinzia; Fanzani, Alessandro; De Angelis, Biagio; Quintarelli, Concetta; Vakoc, Christopher R.; Chen, Eleanor Y.; Megiorni, Francesca; Locatelli, Franco; Valente, Sergio; Mai, Antonello; Rota, Rossella; Marampon, Francesco - 01a Articolo in rivista
paper: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. - - issn: 2058-7716 - wos: WOS:001284933200001 (0) - scopus: 2-s2.0-85200542198 (1)
11573/1696800 - 2024 -
Enhancing sensitivity of triple-negative breast cancer to DNA-damaging therapy through chemical inhibition of the m6A methyltransferase METTL3 Cesaro, Bianca; Iaiza, Alessia; Piscopo, Fabio; Tarullo, Marco; Cesari, Eleonora; Rotili, Dante; Mai, Antonello; Diana, Alberto; Londero, Michela; Del Giacco, Luca; Masetti, Riccardo; Di Leone, Alba; Naro, Chiara; Masciarelli, Silvia; Fontemaggi, Giulia; Sette, Claudio; Fazi, Francesco; Fatica, Alessandro - 01f Lettera, Nota
paper: CANCER COMMUNICATIONS (London: BioMed Central) pp. 282-286 - issn: 2523-3548 - wos: WOS:001125441200001 (5) - scopus: 2-s2.0-85179653539 (7)
11573/1729425 - 2024 -
Activation and inhibition of sirtuins: From bench to bedside Fiorentino, Francesco; Fabbrizi, Emanuele; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
paper: MEDICINAL RESEARCH REVIEWS ([New York, N.Y.] : Wiley) pp. - - issn: 1098-1128 - wos: WOS:001303039100001 (1) - scopus: 2-s2.0-85202827159 (1)
11573/1710159 - 2024 -
Uracil- and Pyridine-containing HDAC inhibitors displayed cytotoxicity in colorectal and glioblastoma cancer stem cells Fiorentino, Francesco; Fabbrizi, Emanuele; Raucci, Alessia; Noce, Beatrice; Fioravanti, Rossella; Valente, Sergio; Paolini, Chantal; De Maria, Ruggero; Steinkühler, Christian; Gallinari, Paola; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. - - issn: 1860-7187 - wos: WOS:001214621100001 (1) - scopus: 2-s2.0-85191719139 (1)
11573/1712838 - 2024 -
m6A modification inhibits miRNAs’ intracellular function, favoring their extracellular export for intercellular communication Garbo, S.; D'andrea, D.; Colantoni, A.; Fiorentino, F.; Mai, A.; Ramos, A.; Tartaglia, G. G.; Tancredi, A.; Tripodi, M.; Battistelli, C. - 01a Articolo in rivista
paper: CELL REPORTS (Elsevier B.V.
Cambridge MA: Cell Press) pp. - - issn: 2211-1247 - wos: WOS:001255604000001 (0) - scopus: 2-s2.0-85195878545 (2)
11573/1701222 - 2024 -
SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process Lambona, Chiara; Zwergel, Clemens; Valente, Sergio; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1662-1689 - issn: 0022-2623 - wos: WOS:001160599300001 (13) - scopus: 2-s2.0-85183983381 (12)
11573/1710803 - 2024 -
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection Maure, Alexandra; Lawarée, Emeline; Fiorentino, Francesco; Pawlik, Alexandre; Gona, Saideep; Giraud-Gatineau, Alexandre; Eldridge, Matthew J. G.; Danckaert, Anne; Hardy, David; Frigui, Wafa; Keck, Camille; Gutierrez, Claude; Neyrolles, Olivier; Aulner, Nathalie; Mai, Antonello; Hamon, Mélanie; Barreiro, Luis B.; Brodin, Priscille; Brosch, Roland; Rotili, Dante; Tailleux, Ludovic - 01a Articolo in rivista
paper: PLOS BIOLOGY (San Francisco, CA : Public Library of Science, c2003-) pp. - - issn: 1545-7885 - wos: WOS:001214097100008 (1) - scopus: 2-s2.0-85191815044 (0)
11573/1703580 - 2024 -
Specific inhibitors of mitochondrial deacylase sirtuin 4 endowed with cellular activity Pannek, M.; Alhalabi, Z.; Tomaselli, D.; Menna, M.; Fiorentino, F.; Robaa, D.; Weyand, M.; Puhlmann, M.; Tomassi, S.; Barreca, F.; Tafani, M.; Zaganjor, E.; Haigis, M. C.; Sippl, W.; Rotili, D.; Mai, A.; Steegborn, C. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 1843-1860 - issn: 1520-4804 - wos: WOS:001160605300001 (4) - scopus: 2-s2.0-85184667987 (4)
11573/1703586 - 2024 -
Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer Pecci, Valeria; Troisi, Fabiola; Aiello, Aurora; De Martino, Sara; Carlino, Angela; Fiorentino, Vincenzo; Ripoli, Cristian; Rotili, Dante; Pierconti, Francesco; Martini, Maurizio; Porru, Manuela; Pinto, Francesco; Mai, Antonello; Bassi, Pier Francesco; Grassi, Claudio; Gaetano, Carlo; Pontecorvi, Alfredo; Strigari, Lidia; Farsetti, Antonella; Nanni, Simona - 01a Articolo in rivista
paper: CANCER CELL INTERNATIONAL ([London]: BioMed Central.) pp. - - issn: 1475-2867 - wos: WOS:001156914300001 (1) - scopus: 2-s2.0-85184414355 (4)
11573/1710160 - 2024 -
Heterocycles-containing HDAC inhibitors active in cancer. An overview of the last fifteen years Raucci, Alessia; Castiello, Carola; Mai, Antonello; Zwergel, Clemens; Valente, Sergio - 01g Articolo di rassegna (Review)
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1-53 - issn: 1860-7179 - wos: WOS:001300014900001 (2) - scopus: 2-s2.0-85202594031 (3)
11573/1714195 - 2024 -
Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1 Spizzichino, Sharon; Di Fonzo, Federica; Marabelli, Chiara; Tramonti, Angela; Chaves-Sanjuan, Antonio; Parroni, Alessia; Boumis, Giovanna; Liberati, Francesca Romana; Paone, Alessio; Montemiglio, Linda Celeste; Ardini, Matteo; Jakobi, Arjen J.; Bharadwaj, Alok; Swuec, Paolo; Tartaglia, Gian Gaetano; Paiardini, Alessandro; Contestabile, Roberto; Mai, Antonello; Rotili, Dante; Fiorentino, Francesco; Macone, Alberto; Giorgi, Alessandra; Tria, Giancarlo; Rinaldo, Serena; Bolognesi, Martino; Giardina, Giorgio; Cutruzzola, Francesca - 01a Articolo in rivista
paper: MOLECULAR CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 2682-2697 - issn: 1097-2765 - wos: WOS:001281962900001 (0) - scopus: 2-s2.0-85198588581 (1)
11573/1729153 - 2024 -
Off-target inhibition of human dihydroorotate dehydrogenase (hDHODH) highlights challenges in the development of fat mass and obesity-associated protein (FTO) inhibitors Tarullo, M.; Fernandez Rodriguez, G.; Iaiza, A.; Venezia, S.; Macone, A.; Incocciati, A.; Masciarelli, S.; Marchioni, M.; Giorgis, M.; Lolli, M. L.; Fornaseri, F.; Proietti, L.; Grebien, F.; Rosignoli, S.; Paiardini, A.; Rotili, D.; Mai, A.; Bochenkova, E.; Caflisch, A.; Fazi, F.; Fatica, A. - 01a Articolo in rivista
paper: ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (Washington DC: American Chemical Society) pp. - - issn: 2575-9108 - wos: WOS:001366197700001 (0) - scopus: 2-s2.0-85210408199 (0)
11573/1700487 - 2024 -
HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling Terri, Michela; Sandoval, Pilar; Bontempi, Giulio; Montaldo, Claudia; Tomero-Sanz, Henar; De Turris, Valeria; Trionfetti, Flavia; Pascual-Antón, Lucía; Clares-Pedrero, Irene; Battistelli, Cecilia; Valente, Sergio; Zwergel, Clemens; Mai, Antonello; Rosanò, Laura; Del Pozo, Miguel Ángel; Sánchez-Álvarez, Miguel; Cabañas, Carlos; Tripodi, Marco; López-Cabrera, Manuel; Strippoli, Raffaele - 01a Articolo in rivista
paper: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. - - issn: 1756-9966 - wos: WOS:001147742000001 (2) - scopus: 2-s2.0-85182865073 (2)
11573/1702828 - 2024 -
Mechanisms of mesothelial cell response to viral infections: HDAC1-3 inhibition blocks poly(I:C)-induced type I interferon response and modulates the mesenchymal/inflammatory phenotype Trionfetti, Flavia; Montaldo, Claudia; Caiello, Ivan; Bontempi, Giulio; Terri, Michela; Tiberi, Marta; Marchant, Vanessa; Domenici, Alessandro; Menè, Paolo; Cordani, Marco; Zwergel, Clemens; Prencipe, Giusi; Ruiz-Ortega, Marta; Valente, Sergio; Mai, Antonello; Tripodi, Marco; Strippoli, Raffaele - 01a Articolo in rivista
paper: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (Lausanne : Frontiers Media SA, 2011-) pp. - - issn: 2235-2988 - wos: WOS:001180097600001 (2) - scopus: 2-s2.0-85187169859 (1)
11573/1705172 - 2024 -
Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy Villares, Marie; Lourenço, Nelly; Ktorza, Ivan; Berthelet, Jérémy; Panagiotou, Aristeidis; Richard, Aurélie; Amo, Angélique; Koziy, Yulianna; Medjkane, Souhila; Valente, Sergio; Fioravanti, Rossella; Pioche-Durieu, Catherine; Lignière, Laurent; Chevreux, Guillaume; Mai, Antonello; Weitzman, Jonathan B. - 01a Articolo in rivista
paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. 1-14 - issn: 2041-1723 - wos: WOS:001185523200018 (1) - scopus: 2-s2.0-85187493170 (1)
11573/1729427 - 2024 -
Successes and challenges in the development of BD1-selective BET inhibitors: a patent review Viviano, Monica; Cipriano, Alessandra; Fabbrizi, Emanuele; Feoli, Alessandra; Castellano, Sabrina; Sbardella, Gianluca; Mai, Antonello; Milite, Ciro; Rotili, Dante - 01g Articolo di rassegna (Review)
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare
-London, United Kingdom: Ashley Publications Limited) pp. 529-545 - issn: 1354-3776 - wos: (0) - scopus: (0)
11573/1661959 - 2023 -
Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells Ansari, Mohammad Salik Zeya; Stagni, Venturina; Iuzzolino, Angela; Rotili, Dante; Mai, Antonello; Del Bufalo, Donatella; Lavia, Patrizia; Degrassi, Francesca; Trisciuoglio, Daniela - 01a Articolo in rivista
paper: CANCER GENE THERAPY (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 124-136 - issn: 0929-1903 - wos: WOS:000854955000001 (11) - scopus: 2-s2.0-85138300847 (12)
11573/1673946 - 2023 -
Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery Aventaggiato, Michele; Barreca, Federica; Vitiello, Laura; Vespa, Simone; Valente, Sergio; Rotili, Dante; Mai, Antonello; Lotti, Lavinia Vittoria; Sansone, Luigi; Russo, Matteo A.; Bizzarri, Mariano; Ferretti, Elisabetta; Tafani, Marco - 01a Articolo in rivista
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000947513100001 (2) - scopus: 2-s2.0-85149752388 (4)
11573/1687782 - 2023 -
SIRT5 Activation and Inorganic Phosphate Binding Reduce Cancer Cell Vitality by Modulating Autophagy/Mitophagy and ROS Barreca, Federica; Aventaggiato, Michele; Vitiello, Laura; Sansone, Luigi; Russo, Matteo Antonio; Mai, Antonello; Valente, Sergio; Tafani, Marco - 01a Articolo in rivista
paper: ANTIOXIDANTS (Basel: MDPI) pp. 1635- - issn: 2076-3921 - wos: WOS:001119091200001 (6) - scopus: 2-s2.0-85169132437 (7)
11573/1694442 - 2023 -
Hydroxamate-based compounds are potent inhibitors of Toxoplasma gondii HDAC biological activity Boissavy, Tom; Rotili, Dante; Mouveaux, Thomas; Roger, Emmanuel; Aliouat, El Moukthar; Pierrot, Christine; Valente, Sergio; Mai, Antonello; Gissot, Mathieu - 01a Articolo in rivista
paper: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (American Society for Microbiology:PO Box 11127:Birmingham, AL 35201:(800)633-4931, (205)995-1567, EMAIL: asm.nonmembers.subs@ebsco.com, INTERNET: http://www.asm.org, Fax: (205)995-1588) pp. e0066123- - issn: 0066-4804 - wos: WOS:001090003100001 (2) - scopus: (0)
11573/1674091 - 2023 -
GreenMedChem. The challenge in the next decade toward eco-friendly compounds and processes in drug design Castiello, Carola; Junghanns, Pierre; Mergel, Annika; Jacob, Claus; Ducho, Christian; Valente, Sergio; Rotili, Dante; Fioravanti, Rossella; Zwergel, Clemens; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: GREEN CHEMISTRY (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 2109-2169 - issn: 1463-9262 - wos: WOS:000946579600001 (42) - scopus: 2-s2.0-85150432512 (49)
11573/1662777 - 2023 -
Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells Di Bello, Elisabetta; Sian, Veronica; Bontempi, Giulio; Zwergel, Clemens; Fioravanti, Rossella; Noce, Beatrice; Castiello, Carola; Tomassi, Stefano; Corinti, Davide; Passeri, Daniela; Pellicciari, Roberto; Mercurio, Ciro; Varasi, Mario; Altucci, Lucia; Tripodi, Marco; Strippoli, Raffaele; Nebbioso, Angela; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 1-18 - issn: 0223-5234 - wos: WOS:000911596400001 (9) - scopus: 2-s2.0-85144323384 (9)
11573/1677023 - 2023 -
Emerging roles of SIRT5 in metabolism, cancer, and SARS-CoV-2 infection Fabbrizi, Emanuele; Fiorentino, Francesco; Carafa, Vincenzo; Altucci, Lucia; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 1-35 - issn: 2073-4409 - wos: WOS:000957394600001 (26) - scopus: 2-s2.0-85151108488 (28)
11573/1694364 - 2023 -
State of the art of carbonic anhydrase activators Fiorentino, Francesco; Carta, Fabrizio; Rotili, Dante; Mai, Antonello; Supuran, Claudiu T - 01m Editorial/Introduzione in rivista
paper: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 2025-2028 - issn: 1756-8919 - wos: WOS:001081530900001 (3) - scopus: 2-s2.0-85177103741 (3)
11573/1689870 - 2023 -
The role of structural biology in the design of sirtuin activators Fiorentino, Francesco; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
paper: CURRENT OPINION IN STRUCTURAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 102666- - issn: 0959-440X - wos: WOS:001057837700001 (5) - scopus: 2-s2.0-85169440750 (5)
11573/1669899 - 2023 -
METTL3 from target validation to the first small-molecule inhibitors. A medicinal chemistry journey Fiorentino, Francesco; Menna, Martina; Rotili, Dante; Valente, Sergio; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 1654-1677 - issn: 1520-4804 - wos: WOS:000932489700001 (34) - scopus: 2-s2.0-85147012551 (40)
11573/1677022 - 2023 -
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII Fiorentino, Francesco; Nocentini, Alessio; Rotili, Dante; Supuran, Claudiu T; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 1-9 - issn: 1475-6366 - wos: WOS:000949495200001 (4) - scopus: 2-s2.0-85150225921 (4)
11573/1677024 - 2023 -
Native mass spectrometry-directed drug discovery. Recent advances in investigating protein function and modulation Fiorentino, Francesco; Rotili, Dante; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: DRUG DISCOVERY TODAY (Elsevier Science Limited Trends Journals:PO Box 331, Haywards Heath RH16 3FG United Kingdom:011 44 1444 475651, EMAIL: ct.subs@rbi.co.uk, Fax: 011 44 1444 445423) pp. 1-14 - issn: 1359-6446 - wos: WOS:000955583400001 (9) - scopus: 2-s2.0-85150033652 (10)
11573/1681512 - 2023 -
First-in-class selective inhibitors of the lysine acetyltransferase KAT8 Fiorentino, Francesco; Sementilli, Sara; Menna, Martina; Turrisi, Federica; Tomassi, Stefano; Pellegrini, Francesca Romana; Iuzzolino, Angela; D'acunzo, Francesca; Feoli, Alessandra; Wapenaar, Hannah; Taraglio, Sophie; Fraschetti, Caterina; Del Bufalo, Donatella; Sbardella, Gianluca; Dekker, Frank J.; Paiardini, Alessandro; Trisciuoglio, Daniela; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 6591-6616 - issn: 1520-4804 - wos: WOS:000988858800001 (6) - scopus: 2-s2.0-85159627845 (6)
11573/1685964 - 2023 -
Histone deacetylase 10: A polyamine deacetylase from the crystal structure to the first inhibitors Lambona, Chiara; Zwergel, Clemens; Fioravanti, Rossella; Valente, Sergio; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: CURRENT OPINION IN STRUCTURAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 1-9 - issn: 0959-440X - wos: (0) - scopus: 2-s2.0-85166517965 (5)
11573/1695097 - 2023 -
BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress Marchant, Vanessa; Trionfetti, Flavia; Tejedor-Santamaria, Lucia; Rayego-Mateos, Sandra; Rotili, Dante; Bontempi, Giulio; Domenici, Alessandro; Menè, Paolo; Mai, Antonello; Martín-Cleary, Catalina; Ortiz, Alberto; Ramos, Adrian M.; Strippoli, Raffaele; Ruiz-Ortega, Marta - 01a Articolo in rivista
paper: ANTIOXIDANTS (Basel: MDPI) pp. 1-19 - issn: 2076-3921 - wos: WOS:001137851500001 (0) - scopus: 2-s2.0-85180466019 (0)
11573/1669922 - 2023 -
Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells Negri, Aide; Marozzi, Marina; Trisciuoglio, Daniela; Rotili, Dante; Mai, Antonello; Rizzi, Federica - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Abingdon Oxfordshire United Kingdom: Taylor & Francis
London: Gordon and Breach, 2002-) pp. 1-12 - issn: 1475-6374 - wos: WOS:000911853100001 (5) - scopus: 2-s2.0-85146193316 (8)
11573/1670227 - 2023 -
LSD1 inhibitors for cancer treatment: Focus on multi-target agents and compounds in clinical trials Noce, Beatrice; Di Bello, Elisabetta; Fioravanti, Rossella; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000935304500001 (32) - scopus: 2-s2.0-85148335525 (53)
11573/1658358 - 2023 -
Chemically diverse S. mansoni HDAC8 inhibitors reduced viability in worm larval and adult stages Noce, Beatrice; Di Bello, Elisabetta; Zwergel, Clemens; Fioravanti, Rossella; Valente, Sergio; Rotili, Dante; Masotti, Andrea; Ansari, Mohammad Salik Zeya; Trisciuoglio, Daniela; Chakrabarti, Alokta; Romier, Christophe; Robaa, Dina; Sippl, Wolfgang; Jung, Manfred; Häberli, Cécile; Keiser, Jennifer; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. - - issn: 1860-7179 - wos: WOS:000879912800001 (7) - scopus: 2-s2.0-85141693563 (7)
11573/1691312 - 2023 -
Targeting ROS production through inhibition of NADPH oxidases Reis, Joana; Gorgulla, Christoph; Massari, Marta; Marchese, Sara; Valente, Sergio; Noce, Beatrice; Basile, Lorenzo; Törner, Ricarda; Cox, Huel; Viennet, Thibault; Yang, Moon Hee; Ronan, Melissa M; Rees, Matthew G; Roth, Jennifer A; Capasso, Lucia; Nebbioso, Angela; Altucci, Lucia; Mai, Antonello; Arthanari, Haribabu; Mattevi, Andrea - 01a Articolo in rivista
paper: NATURE CHEMICAL BIOLOGY (New York, N.Y. : Nature Pub. Group, 2005-) pp. 1540-1550 - issn: 1552-4469 - wos: WOS:001090044900002 (9) - scopus: 2-s2.0-85174921719 (16)
11573/1689849 - 2023 -
Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa. Scribani Rossi, C; Eckartt, K; Scarchilli, E; Angeli, S; Price-Whelan, A; Di Matteo, A; Chevreuil, M; Raynal, B; Arcovito, A; Giacon, N; Fiorentino, F; Rotili, D; Mai, A; Espinosa-Urgel, M; Cutruzzola', F; Dietrich, Lep; Paone, A; Paiardini, A; Rinaldo, S - 01a Articolo in rivista
paper: MICROBIOLOGICAL RESEARCH (Urban & Fischer Verlag Jena:Postfach 100537, D-07705 Jena Germany:011 49 3641 626430, EMAIL: journals@urbanfischer.de, INTERNET: http://www.urbanfischer.de, Fax: 011 49 3641 626500) pp. 127498- - issn: 0944-5013 - wos: WOS:001097478000001 (6) - scopus: 2-s2.0-85173505521 (6)
11573/1696065 - 2023 -
HDAC1-3 inhibition increases SARS-CoV-2 replication and productive infection in lung mesothelial and epithelial cells Trionfetti, Flavia; Alonzi, Tonino; Bontempi, Giulio; Terri, Michela; Battistelli, Cecilia; Montaldo, Claudia; Repele, Federica; Rotili, Dante; Valente, Sergio; Zwergel, Clemens; Matusali, Giulia; Maggi, Fabrizio; Goletti, Delia; Tripodi, Marco; Mai, Antonello; Strippoli, Raffaele - 01a Articolo in rivista
paper: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (Lausanne : Frontiers Media SA, 2011-) pp. - - issn: 2235-2988 - wos: WOS:001130489700001 (4) - scopus: 2-s2.0-85180885673 (5)
11573/1694558 - 2023 -
SIRT6 Protects Against Lipopolysaccharide-Induced Inflammation in Human Pulmonary Lung Microvascular Endothelial Cells Wang, Jinping; Luo, Jinque; Rotili, Dante; Mai, Antonello; Steegborn, Clemens; Xu, Suowen; Jin, Zheng Gen - 01a Articolo in rivista
paper: INFLAMMATION (Springer Nature
New York, NY: Plenum Press) pp. - - issn: 0360-3997 - wos: WOS:001082492200001 (5) - scopus: 2-s2.0-85173797364 (5)
11573/1694680 - 2023 -
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase Zhou, Jujun; Deng, Youchao; Iyamu, Iredia D; Horton, John R; Yu, Dan; Hajian, Taraneh; Vedadi, Masoud; Rotili, Dante; Mai, Antonello; Blumenthal, Robert M; Zhang, Xing; Huang, Rong; Cheng, Xiaodong - 01a Articolo in rivista
paper: ACS CHEMICAL BIOLOGY (Washington, D.C. : American Chemical Society, c2006-) pp. 734-745 - issn: 1554-8937 - wos: WOS:000936764500001 (3) - scopus: 2-s2.0-85148863880 (3)
11573/1664753 - 2023 -
Systematic design of adenosine analogs as inhibitors of a clostridioides difficile-specific DNA adenine methyltransferase required for normal sporulation and persistence Zhou, Jujun; Horton, John R.; Menna, Martina; Fiorentino, Francesco; Ren, Ren; Yu, Dan; Hajian, Taraneh; Vedadi, Masoud; Mazzoccanti, Giulia; Ciogli, Alessia; Weinhold, Elmar; Hüben, Michael; Blumenthal, Robert M.; Zhang, Xing; Mai, Antonello; Rotili, Dante; Cheng, Xiaodong - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 934-950 - issn: 0022-2623 - wos: WOS:000907749800001 (5) - scopus: 2-s2.0-85145455635 (5)
11573/1684985 - 2023 -
Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells Zwergel, Clemens; Aventaggiato, Michele; Garbo, Sabrina; Di Bello, Elisabetta; Fassari, Bruno; Noce, Beatrice; Castiello, Carola; Lambona, Chiara; Barreca, Federica; Rotili, Dante; Fioravanti, Rossella; Schmalz, Thomas; Weyand, Michael; Niedermeier, Amelie; Tripodi, Marco; Colotti, Gianni; Steegborn, Clemens; Battistelli, Cecilia; Tafani, Marco; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9622-9641 - issn: 0022-2623 - wos: WOS:001027732800001 (9) - scopus: 2-s2.0-85165671509 (10)
11573/1659805 - 2023 -
PD-L1 small-molecule modulators: a new hope in epigenetic-based multidrug cancer therapy? Zwergel, Clemens; Fioravanti, Rossella; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: DRUG DISCOVERY TODAY (Elsevier Science Limited Trends Journals:PO Box 331, Haywards Heath RH16 3FG United Kingdom:011 44 1444 475651, EMAIL: ct.subs@rbi.co.uk, Fax: 011 44 1444 445423) pp. - - issn: 1359-6446 - wos: WOS:000917237100004 (13) - scopus: 2-s2.0-85141980634 (12)
11573/1659806 - 2022 -
Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells Bontempi, Giulio; Terri, Michela; Garbo, Sabrina; Montaldo, Claudia; Mariotti, Davide; Bordoni, Veronica; Valente, Sergio; Zwergel, Clemens; Mai, Antonello; Marchetti, Alessandra; Domenici, Alessandro; Menè, Paolo; Battistelli, Cecilia; Tripodi, Marco; Strippoli, Raffaele - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. 965- - issn: 2041-4889 - wos: WOS:000885083500004 (15) - scopus: 2-s2.0-85142134241 (13)
11573/1658360 - 2022 -
Histone lysine demethylase inhibition reprograms prostate cancer metabolism and mechanics Chianese, Ugo; Papulino, Chiara; Passaro, Eugenia; Evers, Tom Mj; Babaei, Mehrad; Toraldo, Antonella; De Marchi, Tommaso; Niméus, Emma; Carafa, Vincenzo; Nicoletti, Maria Maddalena; Del Gaudio, Nunzio; Iaccarino, Nunzia; Randazzo, Antonio; Rotili, Dante; Mai, Antonello; Cappabianca, Salvatore; Mashaghi, Alireza; Ciardiello, Fortunato; Altucci, Lucia; Benedetti, Rosaria - 01a Articolo in rivista
paper: MOLECULAR METABOLISM (Amsterdam : Elsevier) pp. 101561- - issn: 2212-8778 - wos: WOS:000844094200002 (5) - scopus: 2-s2.0-85136069603 (5)
11573/1643002 - 2022 -
Determinants of epigenetic resistance to HDAC inhibitors in dystrophic fibro-adipogenic progenitors Consalvi, S.; Tucciarone, L.; Macri, E.; De Bardi, M.; Picozza, M.; Salvatori, I.; Renzini, A.; Valente, S.; Mai, A.; Moresi, V.; Puri, P. L. - 01a Articolo in rivista
paper: EMBO REPORTS (Oxford : Oxford University Press, 2000-) pp. 1-19 - issn: 1469-221X - wos: WOS:000778177100001 (10) - scopus: 2-s2.0-85127391022 (10)
11573/1705179 - 2022 -
Novel Targeting of DNA Methyltransferase Activity Inhibits Ewing Sarcoma Cell Proliferation and Enhances Tumor Cell Sensitivity to DNA Damaging Drugs by Activating the DNA Damage Response Cristalli, C.; Manara, M. C.; Valente, S.; Pellegrini, E.; Bavelloni, A.; De Feo, A.; Blalock, W.; Di Bello, E.; Pineyro, D.; Merkel, A.; Esteller, M.; Tirado, O. M.; Mai, A.; Scotlandi, K. - 01a Articolo in rivista
paper: FRONTIERS IN ENDOCRINOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-2392 - wos: WOS:000811105900001 (9) - scopus: 2-s2.0-85132379050 (8)
11573/1644085 - 2022 -
Current HDAC inhibitors in clinical trials Di Bello, Elisabetta; Noce, Beatrice; Fioravanti, Rossella; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: CHIMIA (Swiss Chemical Society:Barenplatz 2, CH 3011 Bern Switzerland:011 41 31 3104090, EMAIL: info@swiss-chem-soc.ch, markus.straub@swiss-chem-soc.ch, INTERNET: http://www.swiss-chem-soc.ch, Fax: 011 41 31 3121678) pp. 1-6 - issn: 0009-4293 - wos: WOS:000929447400008 (12) - scopus: 2-s2.0-85132577121 (15)
11573/1650772 - 2022 -
Effects of structurally different HDAC inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni Di Bello, Elisabetta; Noce, Beatrice; Fioravanti, Rossella; Zwergel, Clemens; Valente, Sergio; Rotili, Dante; Fianco, Giulia; Trisciuoglio, Daniela; Mourão, Marina M; Sales, Policarpo; Lamotte, Suzanne; Prina, Eric; Späth, Gerald F; Häberli, Cécile; Keiser, Jennifer; Mai, Antonello - 01a Articolo in rivista
paper: ACS INFECTIOUS DISEASES (Washington, DC : American Chemical Society, 2015-) pp. 1356-1366 - issn: 2373-8227 - wos: WOS:000819851400001 (16) - scopus: 2-s2.0-85134360722 (17)
11573/1623778 - 2022 -
Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity Fioravanti, Rossella; Rodriguez, Veronica; Caroli, Jonatan; Chianese, Ugo; Benedetti, Rosaria; Di Bello, Elisabetta; Noce, Beatrice; Zwergel, Clemens; Corinti, Davide; Viña, Dolores; Altucci, Lucia; Mattevi, Andrea; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 973-985 - issn: 1475-6366 - wos: WOS:000771778600001 (1) - scopus: 2-s2.0-85126852334 (1)
11573/1657352 - 2022 -
Therapeutic potential and activity modulation of the protein lysine deacylase sirtuin 5 Fiorentino, F.; Castiello, C.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9580-9606 - issn: 0022-2623 - wos: WOS:000835071900001 (20) - scopus: 2-s2.0-85135378527 (29)
11573/1638052 - 2022 -
Sirtuin modulators: past, present, and future perspectives Fiorentino, Francesco; Mautone, Nicola; Menna, Martina; D'acunzo, Francesca; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
paper: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. - - issn: 1756-8919 - wos: WOS:000797024400001 (0) - scopus: 2-s2.0-85131771683 (20)
11573/1635728 - 2022 -
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models Menna, M.; Fiorentino, F.; Marrocco, B.; Lucidi, A.; Tomassi, S.; Cilli, D.; Romanenghi, M.; Cassandri, M.; Pomella, S.; Pezzella, M.; Del Bufalo, D.; Zeya Ansari, M. S.; Tomasevic, N.; Mladenovic, M.; Viviano, M.; Sbardella, G.; Rota, R.; Trisciuoglio, D.; Minucci, S.; Mattevi, A.; Rotili, D.; Mai, A. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000804176200002 (18) - scopus: 2-s2.0-85129352278 (18)
11573/1613297 - 2022 -
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription Minisini, Martina; Di Giorgio, Eros; Kerschbamer, Emanuela; Dalla, Emiliano; Faggiani, Massimo; Franforte, Elisa; Meyer-Almes, Franz-Josef; Ragno, Rino; Antonini, Lorenzo; Mai, Antonello; Fiorentino, Francesco; Rotili, Dante; Chinellato, Monica; Perin, Stefano; Cendron, Laura; Weichenberger, Christian X; Angelini, Alessandro; Brancolini, Claudio - 01a Articolo in rivista
paper: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485
Editore precedente:
Information Retrieval ltd., London) pp. - - issn: 0305-1048 - wos: WOS:000764227300001 (15) - scopus: 2-s2.0-85127539205 (15)
11573/1612791 - 2022 -
Inhibition of PKCθ Improves Dystrophic Heart Phenotype and Function in a Novel Model of DMD Cardiomyopathy Morroni, Jacopo; Schirone, Leonardo; Valenti, Valentina; Zwergel, Clemens; Riera, Carles Sánchez; Valente, Sergio; Vecchio, Daniele; Schiavon, Sonia; Ragno, Rino; Mai, Antonello; Sciarretta, Sebastiano; Lozanoska-Ochser, Biliana; Bouchè, Marina - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-16 - issn: 1422-0067 - wos: WOS:000772462700001 (1) - scopus: 2-s2.0-85124895071 (1)
11573/1622839 - 2022 -
A potent HDAC inhibitor blocks Toxoplasma gondii tachyzoite growth and profoundly disrupts parasite gene expression Mouveaux, T.; Rotili, D.; Boissavy, T.; Roger, E.; Pierrot, C.; Mai, A.; Gissot, M. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1-11 - issn: 0924-8579 - wos: WOS:000784446400008 (14) - scopus: 2-s2.0-85124124624 (14)
11573/1664310 - 2022 -
Modulation of virulence-associated traits in Aspergillus fumigatus by BET Inhibitor JQ1 Orekhova, Anastasia; De Angelis, Marta; Cacciotti, Andrea; Reverberi, Massimo; Rotili, Dante; Giorgi, Alessandra; Protto, Virginia; Bonincontro, Graziana; Fiorentino, Francesco; Zgoda, Victor; Mai, Antonello; Palamara, Anna Teresa; Simonetti, Giovanna - 01a Articolo in rivista
paper: MICROORGANISMS (Basel: MDPI) pp. 1-19 - issn: 2076-2607 - wos: WOS:000895665300001 (2) - scopus: 2-s2.0-85144917834 (4)
11573/1614439 - 2022 -
Cytoplasmic HDAC4 regulates the membrane repair mechanism in Duchenne muscular dystrophy Renzini, A.; Marroncelli, N.; Cavioli, G.; Di Francescantonio, S.; Forcina, L.; Lambridis, A.; Di Giorgio, E.; Valente, S.; Mai, A.; Brancolini, C.; Giampietri, C.; Magenta, A.; De Santa, F.; Adamo, S.; Coletti, D.; Moresi, V. - 01a Articolo in rivista
paper: JOURNAL OF CACHEXIA, SARCOPENIA AND MUSCLE (Heidelberg ; Berlin : Springer) pp. 1339-1359 - issn: 2190-5991 - wos: WOS:000755498900001 (13) - scopus: 2-s2.0-85124595217 (12)
11573/1622835 - 2022 -
The nitrobenzoxadiazole derivative NBDHEX behaves as plasmodium falciparum gametocyte selective inhibitor with malaria parasite transmission blocking activity Siciliano, G.; Di Paolo, V.; Rotili, D.; Migale, R.; Pedini, F.; Casella, M.; Camerini, S.; Dalzoppo, D.; Henderson, R.; Huijs, T.; Dechering, K. J.; Mai, A.; Caccuri, A. M.; Lalle, M.; Quintieri, L.; Alano, P. - 01a Articolo in rivista
paper: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. 1-19 - issn: 1424-8247 - wos: WOS:000825152000002 (5) - scopus: 2-s2.0-85123900571 (5)
11573/1657657 - 2022 -
Potent and Specific Activators for Mitochondrial Sirtuins Sirt3 and Sirt5 Suenkel, Benjamin; Valente, Sergio; Zwergel, Clemens; Weiss, Sandra; Di Bello, Elisabetta; Fioravanti, Rossella; Aventaggiato, Michele; Amorim, João A.; Garg, Neha; Kumar, Surinder; Lombard, David B.; Hu, Tuo; Singh, Pankaj K.; Tafani, Marco; Palmeira, Carlos M.; Sinclair, David; Mai, Antonello; Steegborn, Clemens - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 14015-14031 - issn: 0022-2623 - wos: WOS:000878509000001 (23) - scopus: 2-s2.0-85140303478 (26)
11573/1628559 - 2022 -
Biochemical functions and clinical characterizations of the sirtuins in diabetes-induced retinal pathologies Taurone, Samanta; De Ponte, Chiara; Rotili, Dante; De Santis, Elena; Mai, Antonello; Fiorentino, Francesco; Scarpa, Susanna; Artico, Marco; Micera, Alessandra - 01g Articolo di rassegna (Review)
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000782009200001 (13) - scopus: 2-s2.0-85127570606 (13)
11573/1623442 - 2022 -
Targeting the anti-apoptotic Bcl-2 family proteins: Machine learning virtual screening and biological evaluation of new small molecules Valentini, E.; D'aguanno, S.; Di Martile, M.; Montesano, C.; Ferraresi, V.; Patsilinakos, A.; Sabatino, M.; Antonini, L.; Chiacchiarini, M.; Valente, S.; Mai, A.; Colotti, G.; Ragno, R.; Trisciuoglio, D.; Del Bufalo, D. - 01a Articolo in rivista
paper: THERANOSTICS (Wyoming, N.S.W. : Ivyspring International Publisher, 2011-) pp. 2427-2444 - issn: 1838-7640 - wos: WOS:000766737800003 (22) - scopus: 2-s2.0-85126080507 (20)
11573/1503800 - 2021 -
Regulatory interplay between mir-181a-5p and estrogen receptor signaling cascade in breast cancer Benedetti, R.; Papulino, C.; Sgueglia, G.; Chianese, U.; De Marchi, T.; Iovino, F.; Rotili, D.; Mai, A.; Nimeus, E.; Aversana, C. D.; Altucci, L. - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. 1-19 - issn: 2072-6694 - wos: WOS:000614992800001 (10) - scopus: 2-s2.0-85100578967 (14)
11573/1503669 - 2021 -
Amphetamine modulation of long-term object recognition memory in rats: influence of stress Colucci, Paola; Santori, Alessia; Romanelli, Luca; Zwergel, Clemens; Mai, Antonello; Scaccianoce, Sergio; Campolongo, Patrizia - 01a Articolo in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000626890500001 (1) - scopus: 2-s2.0-85102336381 (0)
Fiorentino, F.; Carafa, V.; Favale, G.; Altucci, L.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
paper: CANCERS (Basel: MDPI) pp. 1-26 - issn: 2072-6694 - wos: WOS:000627939700001 (39) - scopus: 2-s2.0-85102076188 (42)
11573/1585511 - 2021 -
Emerging therapeutic potential of SIRT6 modulators Fiorentino, F.; Mai, A.; Rotili, D. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9732-9758 - issn: 0022-2623 - wos: WOS:000677581000007 (46) - scopus: 2-s2.0-85110981411 (45)
11573/1585447 - 2021 -
Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein-protein interactions Fiorentino, F.; Rotili, D.; Mai, A.; Bolla, J. R.; Robinson, C. V. - 01a Articolo in rivista
paper: CHEMICAL COMMUNICATIONS (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 10747-10750 - issn: 1359-7345 - wos: WOS:000700904000001 (9) - scopus: 2-s2.0-85117218452 (10)
11573/1585389 - 2021 -
Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives Fiorentino, Francesco; De Angelis, Marta; Menna, Martina; Rovere, Annarita; Maria Caccuri, Anna; D'acunzo, Francesca; Palamara, Anna Teresa; Nencioni, Lucia; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 2128-2138 - issn: 1475-6366 - wos: WOS:000700847900001 (5) - scopus: 2-s2.0-85116047224 (5)
11573/1611281 - 2021 -
Metabolic rewiring by loss of sirt5 promotes kras-induced pancreatic cancer progression Hu, T.; Shukla, S. K.; Vernucci, E.; He, C.; Wang, D.; King, R. J.; Jha, K.; Siddhanta, K.; Mullen, N. J.; Attri, K. S.; Murthy, D.; Chaika, N. V.; Thakur, R.; Mulder, S. E.; Pacheco, C. G.; Fu, X.; High, R. R.; Yu, F.; Lazenby, A.; Steegborn, C.; Lan, P.; Mehla, K.; Rotili, D.; Chaudhary, S.; Valente, S.; Tafani, M.; Mai, A.; Auwerx, J.; Verdin, E.; Tuveson, D.; Singh, P. K. - 01a Articolo in rivista
paper: GASTROENTEROLOGY (USA: Elsevier
Philadelphia, PA: W B Saunders Company) pp. 1584-1600 - issn: 0016-5085 - wos: WOS:000711484200002 (66) - scopus: 2-s2.0-85115084196 (70)
11573/1447549 - 2021 -
Downregulation of miR-326 and its host gene β-arrestin1 induces pro survival activity of E2F1 and promotes medulloblastoma growth Miele, Evelina; Po, Agnese; Mastronuzzi, Angela; Carai, Andrea; Besharat, Zein Mersini; Pediconi, Natalia; Abballe, Luana; Catanzaro, Giuseppina; Sabato, Claudia; De Smaele, Enrico; Canettieri, Gianluca; Di Marcotullio, Lucia; Vacca, Alessandra; Mai, Antonello; Levrero, Massimo; Pfister, Stefan M; Kool, Marcel; Giangaspero, Felice; Locatelli, Franco; Ferretti, Elisabetta - 01a Articolo in rivista
paper: MOLECULAR ONCOLOGY (Amsterdam : Elsevier Science) pp. - - issn: 1574-7891 - wos: WOS:000603687900001 (10) - scopus: 2-s2.0-85098446777 (9)
11573/1576703 - 2021 -
Sirt5 inhibition induces brown fat-like phenotype in 3t3-l1 preadipocytes Molinari, Francesca; Feraco, Alessandra; Mirabilii, Simone; Saladini, Serena; Sansone, Luigi; Vernucci, Enza; Tomaselli, Giada; Marzolla, Vincenzo; Rotili, Dante; A Russo, Matteo; Ricciardi, Maria Rosaria; Tafuri, Agostino; Mai, Antonello; Caprio, Massimiliano; Tafani, Marco; Armani, Andrea - 01a Articolo in rivista
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 1-17 - issn: 2073-4409 - wos: WOS:000654660100001 (21) - scopus: 2-s2.0-85107437198 (22)
11573/1564224 - 2021 -
Histone-deacetylase 8 drives the immune response and the growth of glioma Mormino, Alessandro; Cocozza, Germana; Fontemaggi, Giulia; Valente, Sergio; Esposito, Vincenzo; Santoro, Antonio; Bernardini, Giovanni; Santoni, Angela; Fazi, Francesco; Mai, Antonello; Limatola, Cristina; Garofalo, Stefano - 01a Articolo in rivista
paper: GLIA (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 1-17 - issn: 0894-1491 - wos: WOS:000678875900001 (17) - scopus: 2-s2.0-85111697220 (17)
11573/1601697 - 2021 -
First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53 Nowak, R. P.; Tumber, A.; Hendrix, E.; Ansari, M. S. Z.; Sabatino, M.; Antonini, L.; Andrijes, R.; Salah, E.; Mautone, N.; Pellegrini, F. R.; Simelis, K.; Kawamura, A.; Johansson, C.; Passeri, D.; Pellicciari, R.; Ciogli, A.; Del Bufalo, D.; Ragno, R.; Coleman, M. L.; Trisciuoglio, D.; Mai, A.; Oppermann, U.; Schofield, C. J.; Rotili, D. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 17031-17050 - issn: 0022-2623 - wos: WOS:000754727400006 (10) - scopus: 2-s2.0-85120646873 (12)
11573/1601812 - 2021 -
JQ1, inibitore delle proteine BET, riduce i fattori di virulenza e la patogenicità di
Aspergillus fumigatus. Orekhova, A.; De Angelis, M.; Protto, V.; Rotili, D.; Mai, A.; A. T., Palamara.; Simonetti, G - 04d Abstract in atti di convegno
conference: Nome convegno (Napoli)
book: 13° Congresso Nazionale della Società Italiana di Microbiologia Farmaceutica Obiettivi e Sfide della Microbiologia Moderna per la Difesa della Salute - ()
11573/1602903 - 2021 -
Sex-dependent effects of the drugs of abuse amphetamine and the smart drug 3,4-methylenedioxypyrovalerone on fear memory generalization in rats Riccardi, Eleonora; Blasi, Eleonora; Zwergel, Clemens; Mai, Antonello; Morena, Maria; Campolongo, Patrizia - 01a Articolo in rivista
paper: NEUROSCIENCE (Oxford: Elsevier Ltd.
Oxford; New York: Pergamon Press) pp. - - issn: 0306-4522 - wos: WOS:000888591600010 (3) - scopus: 2-s2.0-85122538831 (3)
11573/1564901 - 2021 -
Polycomb repressive complex 2 modulation through the development of EZH2–EED interaction inhibitors and EED binders Tomassi, Stefano; Romanelli, Annalisa; Zwergel, Clemens; Valente, Sergio; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 11774-11797 - issn: 0022-2623 - wos: WOS:000692012400002 (25) - scopus: 2-s2.0-85114048578 (31)
11573/1467228 - 2021 -
Novel Pyridine-Based Hydroxamates and 2'-Aminoanilides as Histone Deacetylase Inhibitors: Biochemical Profile and Anticancer Activity Zwergel, Clemens; Di Bello, Elisabetta; Fioravanti, Rossella; Conte, Mariarosaria; Nebbioso, Angela; Mazzone, Roberta; Brosch, Gerald; Mercurio, Ciro; Varasi, Mario; Altucci, Lucia; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 989-999 - issn: 1860-7179 - wos: WOS:000599084500001 (11) - scopus: 2-s2.0-85097525146 (10)
Zwergel, Clemens; Tomaselli, Daniela; Mai, Antonello - 02d Voce di Enciclopedia/Dizionario
book: Encyclopedia of Molecular Pharmacology - (978-3-030-21573-6)
11573/1408683 - 2020 -
The pan-sirtuin inhibitor MC2494 regulates mitochondrial function in a leukemia cell line Carafa, Vincenzo; Russo, Rosita; Della Torre, Laura; Cuomo, Francesca; Dell'aversana, Carmela; Sarno, Federica; Sgueglia, Giulia; Di Donato, Marzia; Rotili, Dante; Mai, Antonello; Nebbioso, Angela; Cobellis, Gilda; Chambery, Angela; Altucci, Lucia - 01a Articolo in rivista
paper: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. - - issn: 2234-943X - wos: WOS:000539644000001 (9) - scopus: 2-s2.0-85085984851 (9)
11573/1414757 - 2020 -
Discovery of the first human arylsulfatase a reversible inhibitor impairing mouse oocyte fertilization Caroselli, Silvia; Zwergel, Clemens; Pirolli, Adele; Sabatino, Manuela; Xu, Zhanjie; Kirsch, Gilbert; Mai, Antonello; Colotti, Gianni; Altieri, Fabio; Canipari, Rita; Valente, Sergio; Ragno, Rino - 01a Articolo in rivista
paper: ACS CHEMICAL BIOLOGY (AMERICAN CHEMICAL SOCiety, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036) pp. 1349-1357 - issn: 1554-8929 - wos: WOS:000543662300010 (4) - scopus: 2-s2.0-85086748074 (4)
11573/1434640 - 2020 -
CDK9 as a valuable target in cancer: from natural compounds inhibitors to current treatment in pediatric soft tissue sarcomas Cassandri, Matteo; Fioravanti, Rossella; Pomella, Silvia; Valente, Sergio; Rotili, Dante; Del Baldo, Giada; De Angelis, Biagio; Rota, Rossella; Mai, Antonello - 01a Articolo in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000565986100001 (27) - scopus: 2-s2.0-85089884656 (32)
11573/1429750 - 2020 -
Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni Coutinho Carneiro, V.; De Abreu Da Silva, I. C.; Amaral, M. S.; Pereira, A. S. A.; Silveira, G. O.; Pires, D. D. S.; Verjovski-Almeida, S.; Dekker, F. J.; Rotili, D.; Mai, A.; Lopes-Torres, E. J.; Robaa, D.; Sippl, W.; Pierce, R. J.; Borrello, M. T.; Ganesan, A.; Lancelot, J.; Thiengo, S.; Fernandez, M. A.; Vicentino, A. R. R.; Mourao, M. M.; Coelho, F. S.; Fantappie, M. R. - 01a Articolo in rivista
paper: PLOS NEGLECTED TROPICAL DISEASES (San Francisco, CA : Public Library of Science) pp. - - issn: 1935-2735 - wos: WOS:000547527200003 (6) - scopus: 2-s2.0-85087471659 (7)
11573/1418417 - 2020 -
The innovative potential of statins in cancer: new targets for new therapies Di Bello, Elisabetta; Zwergel, Clemens; Mai, Antonello; Valente, Sergio - 01g Articolo di rassegna (Review)
paper: FRONTIERS IN CHEMISTRY (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-2646 - wos: WOS:000546786300001 (78) - scopus: 2-s2.0-85087290374 (82)
11573/1382315 - 2020 -
Tranylcypromine-based LSD1 inhibitors: structure-activity relationships, antiproliferative effects in leukemia, and gene target modulation Fioravanti, R.; Romanelli, A.; Mautone, N.; Di Bello, E.; Rovere, A.; Corinti, D.; Zwergel, C.; Valente, S.; Rotili, D.; Botrugno, O. A.; Dessanti, P.; Vultaggio, S.; Vianello, P.; Cappa, A.; Binda, C.; Mattevi, A.; Minucci, S.; Mercurio, C.; Varasi, M.; Mai, A. - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 643-658 - issn: 1860-7179 - wos: WOS:000513271600001 (19) - scopus: 2-s2.0-85079446800 (22)
11573/1425034 - 2020 -
Targeting histone acetylation/deacetylation in parasites: an update (2017–2020) Fioravanti, Rossella; Mautone, Nicola; Rovere, Annarita; Rotili, Dante; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: CURRENT OPINION IN CHEMICAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 65-74 - issn: 1367-5931 - wos: WOS:000568781700011 (42) - scopus: 2-s2.0-85086940284 (44)
11573/1429805 - 2020 -
Properly substituted cyclic Bis-(2-bromobenzylidene) compounds behaved as dual p300/CARM1 Inhibitors and Induced apoptosis in cancer cells Fioravanti, Rossella; Tomassi, Stefano; Di Bello, Elisabetta; Romanelli, Annalisa; Plateroti, Andrea Maria; Benedetti, Rosaria; Conte, Mariarosaria; Novellino, Ettore; Altucci, Lucia; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI
Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:000558002500001 (4) - scopus: 2-s2.0-85088202424 (5)
11573/1585515 - 2020 -
Lysine acetyltransferase inhibitors from natural sources Fiorentino, F.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. 1-15 - issn: 1663-9812 - wos: WOS:000565346900001 (24) - scopus: 2-s2.0-85089907540 (26)
Fiorentino, Francesco; Mai, Antonello; Rotili, Dante - 02a Capitolo o Articolo
book: Histone modifications in therapy - (9780128164228)
11573/1503814 - 2020 -
Diphenylene Iodonium Is a Noncovalent MAO Inhibitor: A Biochemical and Structural Analysis Iacovino, L. G.; Reis, J.; Mai, A.; Binda, C.; Mattevi, A. - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1394-1397 - issn: 1860-7179 - wos: WOS:000539090800001 (6) - scopus: 2-s2.0-85086146476 (6)
11573/1401342 - 2020 -
Identification of Inhibitors to trypanosoma cruzi sirtuins based on compounds developed to human enzymes Matutino Bastos, Tanira; Botelho Pereira Soares, Milena; Haddad Franco, Caio; Alcântara, Laura; Antonini, Lorenzo; Sabatino, Manuela; Mautone, Nicola; Holanda Freitas-Junior, Lucio; Moraes, Carolina Borsoi; Ragno, Rino; Rotili, Dante; Schenkman, Sergio; Mai, Antonello; Silvio Moretti, Nilmar - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000539312100255 (10) - scopus: 2-s2.0-85085293622 (11)
11573/1384850 - 2020 -
Sirtuin modulators: where are we now? A review of patents from 2015 to 2019 Mautone, Nicola; Zwergel, Clemens; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare
-London, United Kingdom: Ashley Publications Limited) pp. - - issn: 1354-3776 - wos: WOS:000526337100001 (44) - scopus: 2-s2.0-85083571564 (45)
11573/1390392 - 2020 -
Altered mitochondrial function in cells carrying a premutation or unmethylated full mutation of the FMR1 gene Nobile, V.; Palumbo, F.; Lanni, S.; Ghisio, V.; Vitali, A.; Castagnola, M.; Marzano, V.; Maulucci, G.; De Angelis, C.; De Spirito, M.; Pacini, L.; D'andrea, L.; Ragno, R.; Stazi, G.; Valente, S.; Mai, A.; Chiurazzi, P.; Genuardi, M.; Neri, G.; Tabolacci, E. - 01a Articolo in rivista
paper: HUMAN GENETICS (Germany: Springer Verlag Germany) pp. 227-245 - issn: 0340-6717 - wos: WOS:000515839900006 (19) - scopus: 2-s2.0-85077526115 (18)
11573/1390388 - 2020 -
Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation Ravasio, R.; Ceccacci, E.; Nicosia, L.; Hosseini, A.; Rossi, P. L.; Barozzi, I.; Fornasari, L.; Zuffo, R. D.; Valente, S.; Fioravanti, R.; Mercurio, C.; Varasi, M.; Mattevi, A.; Mai, A.; Pavesi, G.; Bonaldi, T.; Minucci, S. - 01a Articolo in rivista
paper: SCIENCE ADVANCES (Washington, DC : American Association for the Advancement of Science, 2015-) pp. - - issn: 2375-2548 - wos: WOS:000525751400003 (55) - scopus: 2-s2.0-85083269142 (57)
11573/1390390 - 2020 -
A closer look into NADPH oxidase inhibitors: validation and insight into their mechanism of action Reis, J.; Massari, M.; Marchese, S.; Ceccon, M.; Aalbers, F. S.; Corana, F.; Valente, S.; Mai, A.; Magnani, F.; Mattevi, A. - 01a Articolo in rivista
paper: REDOX BIOLOGY (Amsterdam : Elsevier) pp. - - issn: 2213-2317 - wos: WOS:000537459900002 (62) - scopus: 2-s2.0-85079650979 (68)
11573/1394955 - 2020 -
Design of first-in-class dual EZH2/HDAC inhibitor: biochemical activity and biological evaluation in cancer cells Romanelli, Annalisa; Stazi, Giulia; Fioravanti, Rossella; Zwergel, Clemens; Di Bello, Elisabetta; Pomella, Silvia; Perrone, Clara; Battistelli, Cecilia; Strippoli, Raffaele; Tripodi, Marco; Del Bufalo, Donatella; Rota, Rossella; Trisciuoglio, Daniela; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 977-983 - issn: 1948-5875 - wos: WOS:000535281200056 (51) - scopus: 2-s2.0-85087681122 (54)
11573/1412895 - 2020 -
Detrimental effects of the 'bath salt' methylenedioxypyrovalerone on social play behavior in male rats Schiavi, Sara; Melancia, Francesca; Carbone, Emilia; Buzzelli, Valeria; Manduca, Antonia; Peinado, Patricia Jiménez; Zwergel, Clemens; Mai, Antonello; Campolongo, Patrizia; Vanderschuren, Louk J M J; Trezza, Viviana - 01a Articolo in rivista
paper: NEUROPSYCHOPHARMACOLOGY (Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680) pp. 2012-2019 - issn: 0893-133X - wos: WOS:000539813000001 (4) - scopus: 2-s2.0-85086048601 (6)
11573/1480930 - 2020 -
Recent advances in epigenetic proteolysis targeting chimeras (Epi-PROTACs) Tomaselli, D.; Mautone, N.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000591227400031 (16) - scopus: 2-s2.0-85089918812 (15)
11573/1408685 - 2020 -
Sirt4: a multifaceted enzyme at the crossroads of mitochondrial metabolism and cancer Tomaselli, D.; Steegborn, C.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
paper: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. - - issn: 2234-943X - wos: WOS:000531334700001 (55) - scopus: 2-s2.0-85083986337 (60)
11573/1389775 - 2020 -
From PARP1 to TNKS2 inhibition: A structure-based approach Tomassi, Stefano; Pfahler, Julian; Mautone, Nicola; Rovere, Annarita; Esposito, Chiara; Passeri, Daniela; Pellicciari, Roberto; Novellino, Ettore; Pannek, Martin; Steegborn, Clemens; Paiardini, Alessandro; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. - - issn: 1948-5875 - wos: WOS:000535281200039 (11) - scopus: 2-s2.0-85087107488 (9)
11573/1364390 - 2020 -
Novel quinoline compounds active in cancer cells through coupled DNA methyltransferase inhibition and degradation Zwergel, C.; Fioravanti, R.; Stazi, G.; Sarno, F.; Battistelli, C.; Romanelli, A.; Nebbioso, A.; Mendes, E.; Paulo, A.; Strippoli, R.; Tripodi, M.; Pechalrieu, D.; Arimondo, P. B.; De Luca, T.; Del Bufalo, D.; Trisciuoglio, D.; Altucci, L.; Valente, S.; Mai, A. - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000522477300193 (7) - scopus: 2-s2.0-85079504263 (7)
11573/1216108 - 2019 -
Acute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the rat Atehortua Martinez, Luisa Alessandra; Masniere, Cyriaque; Campolongo, Patrizia; Chasseigneaux, Stéphanie; Callebert, Jacques; Zwergel, Clemens; Mai, Antonello; Laplanche, Jean-Louis; Chen, Huixiong; Etheve-Quelquejeu, Mélanie; Mégarbane, Bruno; Benturquia, Nadia - 01a Articolo in rivista
paper: JOURNAL OF PSYCHOPHARMACOLOGY (Sage Publications Limited:6 Bonhill Street, London EC2A 4PU United Kingdom:011 44 207 3740645, EMAIL: journals@sagepub.co.uk, INTERNET: http://www.sagepub.co.uk/ltd_home.htm, Fax: 011 44 207 3748741) pp. 392-405 - issn: 0269-8811 - wos: WOS:000461559100013 (20) - scopus: 2-s2.0-85060763371 (21)
11573/1355613 - 2019 -
H19-dependent transcriptional regulation of β3 and β4 integrins upon estrogen and hypoxia favors metastatic potential in prostate cancer Bacci, L.; Aiello, A.; Ripoli, C.; Loria, R.; Pugliese, D.; Pierconti, F.; Rotili, D.; Strigari, L.; Pinto, F.; Bassi, P. F.; Mai, A.; Grassi, C.; Pontecorvi, A.; Falcioni, R.; Farsetti, A.; Nanni, S. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000484411100169 (23) - scopus: 2-s2.0-85071378179 (22)
11573/1355598 - 2019 -
Inhibition of histone demethylases LSD1 and UTX regulates ERα signaling in breast cancer Benedetti, R.; Dell'aversana, C.; De Marchi, T.; Rotili, D.; Liu, N. Q.; Novakovic, B.; Boccella, S.; Di Maro, S.; Cosconati, S.; Baldi, A.; Nimeus, E.; Schultz, J.; Hoglund, U.; Maione, S.; Papulino, C.; Chianese, U.; Iovino, F.; Federico, A.; Mai, A.; Stunnenberg, H. G.; Nebbioso, A.; Altucci, L. - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000507382100204 (36) - scopus: 2-s2.0-85077269849 (38)
11573/1193778 - 2019 -
Identification of novel quinazoline derivatives as potent antiplasmodial agents Bouchut, A; Rotili, D; Pierrot, C; Valente, S; Lafitte, S; Schultz, J; Hoglund, U; Mazzone, R; Lucidi, A; Fabrizi, G; Pechalrieu, D; Arimondo, Pb; Skinner-Adams, Ts; Chua, Mj; Andrews, Kt; Mai, A; Khalife, J. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 277-291 - issn: 0223-5234 - wos: WOS:000451498200018 (47) - scopus: 2-s2.0-85055197167 (49)
11573/1336693 - 2019 -
Enzymatic and biological characterization of novel sirtuin modulators against cancer Carafa, V.; Poziello, A.; Torre, L. D.; Giovannelli, P.; Di Donato, M.; Safadeh, E.; Yu, Z.; Baldi, A.; Castoria, G.; Tomaselli, D.; Mai, A.; Rotili, D.; Nebbioso, A.; Altucci, L. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000502786800136 (11) - scopus: 2-s2.0-85074828780 (13)
11573/1333610 - 2019 -
Amphetamine and the Smart Drug 3,4-Methylenedioxypyrovalerone (MDPV) Induce Generalization of Fear Memory in Rats Colucci, Paola; Mancini, Giulia Federica; Santori, Alessia; Zwergel, Clemens; Mai, Antonello; Trezza, Viviana; Roozendaal, Benno; Campolongo, Patrizia - 01a Articolo in rivista
paper: FRONTIERS IN MOLECULAR NEUROSCIENCE (Lausanne: Frontiers Research Foundation, 2008-) pp. - - issn: 1662-5099 - wos: WOS:000502730100001 (11) - scopus: 2-s2.0-85076905906 (11)
11573/1390394 - 2019 -
The Protein Arginine Methyltransferases 1 and 5 affect Myc properties in glioblastoma stem cells Favia, A.; Salvatori, L.; Nanni, S.; Iwamoto-Stohl, L. K.; Valente, S.; Mai, A.; Scagnoli, F.; Fontanella, R. A.; Totta, P.; Nasi, S.; Illi, B. - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature
London: Nature Publishing Group) pp. 15925- - issn: 2045-2322 - wos: WOS:000493898100033 (32) - scopus: 2-s2.0-85074323285 (32)
11573/1336760 - 2019 -
DNA Methylation: Biological Implications and Modulation of Its Aberrant Dysregulation Lucidi, Alessia; Tomaselli, Daniela; Rotili, Dante; Mai, Antonello - 02a Capitolo o Articolo
book: The DNA, RNA, and Histone Methylomes - (978-3-030-14791-4; 978-3-030-14792-1)
11573/1390399 - 2019 -
Statins and histone deacetylase inhibitors affect lamin A/C - histone deacetylase 2 interaction in human cells Mattioli, Elisabetta; Andrenacci, Davide; Mai, Antonello; Valente, Sergio; Robijns, Joke; De Vos, Winnok H; Capanni, Cristina; Lattanzi, Giovanna - 01a Articolo in rivista
paper: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-634X - wos: WOS:000467197300001 (18) - scopus: 2-s2.0-85075855435 (15)
11573/1238934 - 2019 -
The emerging role of epigenetics in human autoimmune disorders Mazzone, Roberta; Zwergel, Clemens; Artico, Marco; Taurone, Samanta; Ralli, Massimo; Greco, Antonio; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. - - issn: 1868-7083 - wos: WOS:000459879000001 (178) - scopus: 2-s2.0-85062452532 (208)
11573/1336715 - 2019 -
Structure-reactivity relationships on substrates and inhibitors of the lysine deacylase sirtuin 2 from schistosoma mansoni (SmSirt2) Monaldi, Daria; Rotili, Dante; Julien Lancelot, ‡; Martin Marek, §; Nathalie Wössner, ∥; Lucidi, Alessia; Tomaselli, Daniela; Elizabeth Ramos-Morales, ‡; Christophe Romier, ∥; Pierce, ∥ Raymond J.; Mai, Antonello; And Manfred Jung, ‡ - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8733-8759 - issn: 0022-2623 - wos: WOS:000490355000005 (20) - scopus: 2-s2.0-85072924967 (19)
11573/1221842 - 2019 -
Effect of α-methoxy substitution on the anti-HIV activity of dihydropyrimidin-4(3 H)-ones Nawrozkij, Maxim B.; Forgione, Mariantonietta; Yablokov, Alexandre S.; Lucidi, Alessia; Tomaselli, Daniela; Patsilinakos, Alexandros; Panella, Cristina; Hailu, Gebremedhin S.; Kirillov, Ivan A.; Badia, Roger; Riveira-Munoz, Eva; Crespan, Emmanuele; Armijos Rivera, Jorge I.; Cirilli, Roberto; Ragno, Rino; Esté, José A.; Maga, Giovanni; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 604-621 - issn: 0022-2623 - wos: WOS:000457067600015 (14) - scopus: 2-s2.0-85059424455 (12)
11573/1336742 - 2019 -
α,γ-Diketocarboxylic acids and their esters act as carbonic anhydrase IX and XII selective inhibitors Nocentini, Alessio; Lucidi, Alessia; Perut, Francesca; Massa, Annamaria; Tomaselli, Daniela; Gratteri, Paola; Baldini, Nicola; Rotili, Dante; Mai, Antonello; Supuran, Claudiu T. - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 661-665 - issn: 1948-5875 - wos: WOS:000464767700047 (18) - scopus: 2-s2.0-85064255109 (19)
11573/1339733 - 2019 -
Epigenetic modulators as a new strategies to reduce Aspergillus pathogenicity Orekhova, Anastasia; D’Auria, F. D.; Rotili, D.; Mai, A.; Palamara, A. T.; Simonetti, G - 04f Poster
conference: 47° Congresso Nazionale della Società Italiana di Microbiologia (Roma)
book: 47° Congresso Nazionale della Società Italiana di Microbiologia - ()
11573/1390396 - 2019 -
Histone deacetylases contribute to excitotoxicity-triggered degeneration of retinal ganglion cells in vivo Schluter, A.; Aksan, B.; Fioravanti, R.; Valente, S.; Mai, A.; Mauceri, D. - 01a Articolo in rivista
paper: MOLECULAR NEUROBIOLOGY (Humana Press Incorporated:999 Riverview Drive, Suite 208:Totowa, NJ 07512:(973)256-1699, EMAIL: lglasner@humanapr.com, INTERNET: http://www.humanapress.com, Fax: (973)256-8341) pp. 8018-8034 - issn: 0893-7648 - wos: WOS:000494860800008 (23) - scopus: 2-s2.0-85067067374 (25)
11573/1355609 - 2019 -
Comparison of the effects of synthetic and plant-derived mTOR regulators on healthy human ovarian cells Sirotkin, A. V.; Adamcova, E.; Rotili, D.; Mai, A.; Mlyncek, M.; Mansour, L.; Alwasel, S.; Harrath, A. H. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF PHARMACOLOGY (AMSTERDAM, NETHERLANDS: ELSEVIER SCIENCE) pp. 70-78 - issn: 0014-2999 - wos: WOS:000468305200009 (1) - scopus: 2-s2.0-85063965408 (2)
11573/1339079 - 2019 -
Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype Stazi, G.; Taglieri, L.; Nicolai, Alice; Romanelli, A.; Fioravanti, R.; Morrone, S.; Sabatino, M.; Ragno, R.; Taurone, S.; Nebbioso, M.; Carletti, R.; Artico, M.; Valente, S.; Scarpa, S.; Mai, A. - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. 1-17 - issn: 1868-7083 - wos: WOS:000501362500004 (52) - scopus: 2-s2.0-85076062797 (50)
11573/1208206 - 2019 -
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells Stazi, Giulia; Battistelli, Cecilia; Piano, Valentina; Mazzone, Roberta; Marrocco, Biagina; Marchese, Sara; Louie, Sharon M.; Zwergel, Clemens; Antonini, Lorenzo; Patsilinakos, Alexandros; Ragno, Rino; Viviano, Monica; Sbardella, Gianluca; Ciogli, Alessia; Fabrizi, Giancarlo; Cirilli, Roberto; Strippoli, Raffaele; Marchetti, Alessandra; Tripodi, Marco; Nomura, Daniel K.; Mattevi, Andrea; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 722-735 - issn: 0223-5234 - wos: WOS:000458597300053 (16) - scopus: 2-s2.0-85058530369 (17)
11573/1416968 - 2019 -
Histone deacetylases as an epigenetic pillar for the development of hybrid inhibitors in cancer Stazi, Giulia; Fioravanti, Rossella; Mai, Antonello; Mattevi, Andrea; Valente, Sergio - 01g Articolo di rassegna (Review)
paper: CURRENT OPINION IN CHEMICAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 89-100 - issn: 1367-5931 - wos: WOS:000473839100012 (27) - scopus: 2-s2.0-85064167463 (30)
11573/1275490 - 2019 -
Epigenetic Pharmacology in Regenerative Medicine (Epi-Drugs) Stazi, Giulia; Zwergel, Clemens; Valente, Sergio; Mai, Antonello - 02a Capitolo o Articolo
book: Epigenetics and Regeneration - (9780128148792)
11573/1336730 - 2019 -
Epigenetic polypharmacology: a new frontier for epi-drug discovery Tomaselli, Daniela; Lucidi, Alessia; Rotili, Dante; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: MEDICINAL RESEARCH REVIEWS ([New York, N.Y.] : Wiley) pp. 190-244 - issn: 1098-1128 - wos: WOS:000534635500009 (80) - scopus: 2-s2.0-85075138650 (89)
11573/1355602 - 2019 -
Histone deacetylase inhibitors exert anti-tumor effects on human adherent and stem-like glioma cells 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis Was, H.; Krol, S. K.; Rotili, D.; Mai, A.; Wojtas, B.; Kaminska, B.; Maleszewska, M. - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. 11- - issn: 1868-7083 - wos: WOS:000456005400002 (57) - scopus: 2-s2.0-85060173887 (56)
Zwergel, Clemens; Rotili, Dante; Valente, Sergio; Mai, Antonello - 02a Capitolo o Articolo
book: Epigenetic Drug Discovery - (9783527343140; 9783527809257)
11573/1265927 - 2019 -
Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells Zwergel, Clemens; Schnekenburger, Michael; Sarno, Federica; Battistelli, Cecilia; Manara, Maria Cristina; Stazi, Giulia; Mazzone, Roberta; Fioravanti, Rossella; Gros, Christina; Ausseil, Frédéric; Florean, Cristina; Nebbioso, Angela; Strippoli, Raffaele; Ushijima, Toshikazu; Scotlandi, Katia; Tripodi, Marco; Arimondo, Paola B.; Altucci, Lucia; Diederich, Marc; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. - - issn: 1868-7083 - wos: WOS:000467227900001 (28) - scopus: 2-s2.0-85065468885 (32)
Blanquart, Christophe; Linot, Camille; Cartron, Pierre-Francois; Tomaselli, Daniela; Mai, Antonello; Bertrand, Philippe - 01a Articolo in rivista
paper: CURRENT MEDICINAL CHEMISTRY (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. - - issn: 0929-8673 - wos: WOS:000477048900011 (11) - scopus: 2-s2.0-85071053394 (15)
11573/1147229 - 2018 -
Effects of class II-selective histone deacetylase inhibitor on neuromuscular function and disease progression in SOD1-ALS mice Buonvicino, Daniela; Felici, Roberta; Ranieri, Giuseppe Antonio; Caramelli, Riccardo; Lapucci, Andrea; Cavone, Leonardo; Muzzi, Mirko; Di Pietro, Lorena; Bernardini, Camilla; Zwergel, Clemens; Valente, Sergio; Mai, Antonello; Chiarugi, Alberto - 01a Articolo in rivista
paper: NEUROSCIENCE (Oxford: Elsevier Ltd.
Oxford; New York: Pergamon Press) pp. 228-238 - issn: 0306-4522 - wos: WOS:000430884100020 (19) - scopus: 2-s2.0-85044974964 (19)
11573/1116555 - 2018 -
RIP1-HAT1-SirT complex identification and targeting in treatment and prevention of cancer Carafa, Vincenzo; Nebbioso, Angela; Cuomo, Francesca; Rotili, Dante; Cobellis, Gilda; Bontempo, Paola; Baldi, Alfonso; Spugnini, Enrico P.; Citro, Alfonso Gennaro; Chambery, Angela; Russo, Rosita; Ciana, Paolo; Maravigna, Luca; Shaik, Jani; Radaelli, Enrico; De Antonellis, Pasquale; Tarantino, Domenico; Pirolli, Adele; Ragno, Rino; Massimo Zollo, .; Stunnenberg, Hendrik G.; Mai, Antonello; Altucci, Lucia - 01a Articolo in rivista
paper: CLINICAL CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 2886-2900 - issn: 1078-0432 - wos: WOS:000435462700019 (37) - scopus: 2-s2.0-85052287980 (40)
11573/1115449 - 2018 -
KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2 Cocco, Elisa; Leo, Manuela; Canzonetta, Claudia; Di Vito, Serena; Mai, Antonello; Rotili, Dante; Di Napoli, Arianna; Vecchione, Andrea; De Nunzio, Cosimo; Filetici, Patrizia; Stoppacciaro, Antonella - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. 1-16 - issn: 1868-7083 - wos: WOS:000429840100001 (11) - scopus: 2-s2.0-85045003305 (16)
11573/1174048 - 2018 -
Six years (2012-2018) of researches on catalytic EZH2 inhibitors: the boom of the 2-pyridone compounds Fioravanti, R; Stazi, G; Zwergel, C; Valente, S; Mai, A. - 01a Articolo in rivista
paper: THE CHEMICAL RECORD (New York N.Y.: Wiley, c2000-) pp. 1818-1832 - issn: 1527-8999 - wos: WOS:000453386600014 (84) - scopus: 2-s2.0-85055289007 (87)
11573/1147231 - 2018 -
Lysine acetyltransferase inhibitors: structure-activity relationships and potential therapeutic implications Fiorentino, Francesco; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
paper: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 1067-1091 - issn: 1756-8919 - wos: WOS:000431874300008 (24) - scopus: 2-s2.0-85046873546 (24)
11573/1174039 - 2018 -
Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells Iachettini, Sara; Trisciuoglio, Daniela; Rotili, Dante; Lucidi, Alessia; Salvati, Erica; Zizza, Pasquale; Di Leo, Luca; Del Bufalo, Donatella; Rosa Ciriolo, Maria; Leonetti, Carlo; Steegborn, Clemens; Mai, Antonello; Rizzo, Angela; Annamaria Biroccio, And - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. 996- - issn: 2041-4889 - wos: WOS:000446267200026 (71) - scopus: 2-s2.0-85053859793 (80)
11573/1074176 - 2018 -
Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors Kalin, Jay H.; Wu, Muzhou; Gomez, Andrea V.; Song, Yun; Das, Jayanta; Hayward, Dawn; Adejola, Nkosi; Wu, Mingxuan; Panova, Izabela; Chung, Hye Jin; Kim, Edward; Roberts, Holly J.; Roberts, Justin M.; Prusevich, Polina; Jeliazkov, Jeliazko R.; Roy Burman, Shourya S.; Fairall, Louise; Milano, Charles; Eroglu, Abdulkerim; Proby, Charlotte M.; Dinkova-Kostova, Albena T.; Hancock, Wayne W.; Gray, Jeffrey J.; Bradner, James E.; Valente, Sergio; Mai, Antonello; Anders, Nicole M.; Rudek, Michelle A.; Hu, Yong; Ryu, Byungwoo; Schwabe, John W. R.; Mattevi, Andrea; Alani, Rhoda M.; Cole, Philip A. - 01a Articolo in rivista
paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. - - issn: 2041-1723 - wos: WOS:000419404200003 (206) - scopus: 2-s2.0-85040217796 (177)
11573/1147949 - 2018 -
A quinoline-based DNA methyltransferase inhibitor as a possible adjuvant in osteosarcoma therapy Manara, Maria Cristina; Valente, Sergio; Cristalli, Camilla; Nicoletti, Giordano; Landuzzi, Lorena; Zwergel, Clemens; Mazzone, Roberta; Stazi, Giulia; Arimondo, Paola B.; Pasello, Michela; Guerzoni, Clara; Picci, Piero; Nanni, Patrizia; Lollini, Pier-Luigi; Mai, Antonello; Scotlandi, Katia - 01a Articolo in rivista
paper: MOLECULAR CANCER THERAPEUTICS (Philadelphia, PA : American Association for Cancer Research, c2001-) pp. 1881-1892 - issn: 1535-7163 - wos: WOS:000444041300008 (32) - scopus: 2-s2.0-85053014459 (32)
11573/1147243 - 2018 -
Altered modulation of lamin A/C-HDAC2 interaction and p21 expression during oxidative stress response in HGPS Mattioli, Elisabetta; Andrenacci, Davide; Garofalo, Cecilia; Prencipe, Sabino; Scotlandi, Katia; Remondini, Daniel; Gentilini, Davide; Di Blasio, Anna Maria; Valente, Sergio; Scarano, Emanuela; Cicchilitti, Lucia; Piaggio, Giulia; Mai, Antonello; Lattanzi, Giovanna - 01a Articolo in rivista
paper: AGING CELL ([Oxford] : Blackwell Science Ltd, 2002-) pp. - - issn: 1474-9726 - wos: WOS:000445599100019 (34) - scopus: 2-s2.0-85052612287 (35)
11573/1147233 - 2018 -
Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells Mellini, Paolo; Marrocco, Biagina; Borovika, Diana; Polletta, Lucia; Carnevale, Ilaria; Saladini, Serena; Stazi, Giulia; Zwergel, Clemens; Trapencieris, Peteris; Ferretti, Elisabetta; Tafani, Marco; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: PHILOSOPHICAL TRANSACTIONS - ROYAL SOCIETY. BIOLOGICAL SCIENCES (Royal Society of London) pp. 20170150- - issn: 0962-8436 - wos: WOS:000430738400014 (20) - scopus: 2-s2.0-85045959069 (21)
11573/1147245 - 2018 -
Nucleocytoplasmic export of HDAC5 and SIRT2 downregulation: two epigenetic mechanisms by which antidepressants enhance synaptic plasticity markers Muñoz-Cobo, I.; Erburu, M. M.; Zwergel, C.; Cirilli, Raffaela; Mai, A.; Valente, S.; Puerta, E.; Tordera, Rosa M. - 01a Articolo in rivista
paper: PSYCHOPHARMACOLOGY (Heidelberg; Berlin: Springer) pp. 2831-2846 - issn: 0033-3158 - wos: WOS:000446140500005 (10) - scopus: 2-s2.0-85051492076 (9)
11573/1225570 - 2018 -
EZH2, HIF-1, and their inhibitors: An overview on pediatric cancers Papale, Marco; Ferretti, Elisabetta; Battaglia, Giuseppe; Bellavia, Diana; Mai, Antonello; Tafani, Marco - 01g Articolo di rassegna (Review)
paper: FRONTIERS IN PEDIATRICS (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-2360 - wos: WOS:000450498300001 (13) - scopus: 2-s2.0-85058208629 (13)
11573/1147237 - 2018 -
Combined HAT/EZH2 modulation leads to cancer-selective cell death Petraglia, Francesca; Singh, Abhishek A.; Carafa, Vincenzo; Nebbioso, Angela; Conte, Mariarosaria; Scisciola, Lucia; Valente, Sergio; Baldi, Alfonso; Mandoli, Amit; Petrizzi, Valeria Belsito; Ingenito, Concetta; De Falco, Sandro; Cicatiello, Valeria; Apicella, Ivana; Janssen-Megens, Eva M.; Kim, Bowon; Yi, Guoqiang; Logie, Colin; Heath, Simon; Ruvo, Menotti; Wierenga, Albertus T. J.; Flicek, Paul; Yaspo, Marie Laure; Della Valle, Veronique; Bernard, Olivier; Tomassi, Stefano; Novellino, Ettore; Feoli, Alessandra; Sbardella, Gianluca; Gut, Ivo; Vellenga, Edo; Stunnenberg, Hendrik G.; Mai, Antonello; Martens, Joost H. A.; Altucci, Lucia - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 25630-25646 - issn: 1949-2553 - wos: (0) - scopus: 2-s2.0-85047400725 (6)
11573/1120934 - 2018 -
HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal Rossi, Lucia; Battistelli, Cecilia; De Turris, Valeria; Noce, Valeria; Zwergel, Clemens; Valente, Sergio; Moioli, Alessandra; Manzione, Andrea; Palladino, Marco; Bordoni, Veronica; Domenici, Alessandro; Mene', Paolo; Mai, Antonello; Tripodi, Marco; Strippoli, Raffaele - 01a Articolo in rivista
paper: OPEN ACCESS SCIENTIFIC REPORTS (Los Angeles, CA : OMICS Publishing Group, [2012]-) pp. - - issn: 2332-2675 - wos: WOS:000433547600053 (24) - scopus: 2-s2.0-85048002226 (26)
11573/1065694 - 2018 -
Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches Sabatino, Manuela; Rotili, Dante; Patsilinakos, Alexandros; Forgione, Mariantonietta; Tomaselli, Daniela; Alby, Fréderic; Arimondo, Paola B.; Mai, Antonello; Ragno, Rino - 01a Articolo in rivista
paper: JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (-SPRINGER, VAN GODEWIJCKSTRAAT 30, DORDRECHT, NETHERLANDS, 3311 GZ
-Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: frontoffice@wkap.nl, kluweronline@wkap.nl, INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254) pp. 435-458 - issn: 0920-654X - wos: WOS:000425293300003 (15) - scopus: 2-s2.0-85041359880 (16)
11573/1147239 - 2018 -
Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia Singh, Abhishek A.; Petraglia, Francesca; Nebbioso, Angela; Yi, Guoqiang; Conte, Mariarosaria; Valente, Sergio; Mandoli, Amit; Scisciola, Lucia; Lindeboom, Rik; Kerstens, Hinri; Janssen-Megens, Eva M.; Pourfarzad, Farzin; Habibi, Ehsan; Berentsen, Kim; Kim, Bowon; Logie, Colin; Heath, Simon; Wierenga, Albertus T. J.; Clarke, Laura; Flicek, Paul; Jansen, Joop H.; Kuijpers, Taco; Yaspo, Marie Laure; Della Valle, Veronique; Bernard, Olivier; Gut, Ivo; Vellenga, Edo; Stunnenberg, Hendrik G.; Mai, Antonello; Altucci, Lucia; Martens, Joost H. A. - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 25647-25660 - issn: 1949-2553 - wos: (0) - scopus: 2-s2.0-85047385574 (13)
11573/1202973 - 2018 -
Application of small epigenetic modulators in pediatric medulloblastoma Zwergel, Clemens; Romanelli, Annalisa; Stazi, Giulia; Besharat, Zein Mersini; Catanzaro, Giuseppina; Tafani, Marco; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: FRONTIERS IN PEDIATRICS (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-2360 - wos: WOS:000452081000001 (13) - scopus: 2-s2.0-85058706178 (15)
11573/1147235 - 2018 -
Trends of LSD1 inhibitors in viral infections Zwergel, Clemens; Stazi, Giulia; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 1133-1135 - issn: 1756-8919 - wos: WOS:000433568500001 (10) - scopus: 2-s2.0-85048066484 (10)
11573/955900 - 2017 -
Essential oil extraction, chemical analysis and anti-candida activity of calamintha nepeta (L.) Savi subsp. glandulosa (Req.) ball-new approaches Božovic, Mijat; Garzoli, Stefania; Sabatino, Manuela; Pepi, Federico; Baldisserotto, Anna; Andreotti, Elisa; Romagnoli, Carlo; Mai, Antonello; Manfredini, Stefano; Ragno, Rino - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI
Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:000395552400017 (30) - scopus: 2-s2.0-85013989667 (38)
11573/1602341 - 2017 -
Corrigendum: Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma Coni, S.; Mancuso, A. B.; Di Magno, L.; Sdruscia, G.; Manni, S.; Serrao, S. M.; Rotili, D.; Spiombi, E.; Bufalieri, F.; Petroni, M.; Kusio-Kobialka, M.; De Smaele, E.; Ferretti, E.; Capalbo, C.; Mai, A.; Niewiadomski, P.; Screpanti, I.; Di Marcotullio, L.; Canettieri, G. - 01b Commento, Erratum, Replica e simili
paper: SCIENTIFIC REPORTS (London: Springer Nature
London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000399974300001 (5) - scopus: 2-s2.0-85068766477 (4)
11573/946157 - 2017 -
Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma. Coni, Sonia; Mancuso, Anna Barbara; Di Magno, L; Sdruscia, Giulia; Manni, Simona; Serrao, Silvia Maria; Rotili, Dante; Spiombi, Eleonora; Bufalieri, Francesca; Petroni, Marialaura; Kusio Kobialka, M; De Smaele, Enrico; Ferretti, Elisabetta; Capalbo, Carlo; Mai, Antonello; Niewiadomski, P; Screpanti, Isabella; Di Marcotullio, Lucia; Canettieri, Gianluca - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature
London: Nature Publishing Group) pp. 44079- - issn: 2045-2322 - wos: WOS:000396136700001 (54) - scopus: 2-s2.0-85014895304 (54)
11573/1147224 - 2017 -
Attenuation of diet-induced obesity and induction of white fat browning with a chemical inhibitor of histone deacetylases Ferrari, A.; Fiorino, E.; Longo, R.; Barilla, S.; Mitro, N.; Cermenati, G.; Giudici, M.; Caruso, D.; Mai, A.; Guerrini, U.; De Fabiani, E.; Crestani, M. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF OBESITY (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 289-298 - issn: 0307-0565 - wos: WOS:000394143700012 (39) - scopus: 2-s2.0-85006511908 (44)
11573/944092 - 2017 -
A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability. Fulci, C; Rotili, Dante; De Luca, A; Stella, L; Morozzo Della Rocca, B; Forgione, M; Di Paolo, V; Mai, Antonello; Falconi, M; Quintieri, L; Caccuri, Am; 7, . - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 240-247 - issn: 1475-6366 - wos: WOS:000392591100017 (19) - scopus: 2-s2.0-85015590345 (19)
11573/1027812 - 2017 -
Lysine deacetylase inhibitors in parasites: past, present, and future perspectives. Hailu, Gs; Robaa, D; Forgione, M; Sippl, W; Rotili, D; Mai, A. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4780-4804 - issn: 0022-2623 - wos: WOS:000404202200002 (73) - scopus: 2-s2.0-85021131721 (76)
11573/1092479 - 2017 -
Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice Lapucci, Andrea; Cavone, Leonardo; Buonvicino, Daniela; Felici, Roberta; Gerace, Elisabetta; Zwergel, Clemens; Valente, Sergio; Mai, Antonello; Chiarugi, Alberto - 01a Articolo in rivista
paper: NEUROSCIENCE LETTERS (Limerick Ireland: Elsevier Science Ireland Limited) pp. 120-125 - issn: 0304-3940 - wos: WOS:000409288600019 (19) - scopus: 2-s2.0-85026360880 (22)
11573/1192249 - 2017 -
Structure-activity relationships on cynnamoyl derivatives as inhibitors of p300 Histone acetyltransferase Madia, Valentina Noemi; Benedetti, Rosaria; Letizia Barreca, Maria; Ngo, Liza; Pescatori, Luca; Messore, Antonella; Pupo, Giovanni; Saccoliti, Francesco; Valente, Sergio; Mai, Antonello; Scipione, Luigi; George Zheng, Yujun; Tintori, Cristina; Botta, Maurizio; Cecchetti, Violetta; Altucci, Lucia; Di Santo, Roberto; Costi, Roberta - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1359-1368 - issn: 1860-7187 - wos: WOS:000429592300014 (10) - scopus: 2-s2.0-85017448829 (9)
11573/972511 - 2017 -
Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy Mazzone, Roberta; Zwergel, Clemens; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. 1-15 - issn: 1868-7083 - wos: WOS:000403112500004 (112) - scopus: 2-s2.0-85020006586 (119)
11573/1017610 - 2017 -
The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells Miele, Evelina; Valente, Sergio; Alfano, Vincenzo; Silvano, Marianna; Mellini, Paolo; Borovika, Diana; Marrocco, Biagina; Po, Agnese; Besharat, Zein Mersini; Catanzaro, Giuseppina; Battaglia, Giuseppe; Abballe, Luana; Zwergel, Clemens; Stazi, Giulia; Milite, Ciro; Castellano, Sabrina; Tafani, Marco; Trapencieris, Peteris; Mai, Antonello; Ferretti, Elisabetta - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 68557-68570- - issn: 1949-2553 - wos: WOS:000410790500145 (36) - scopus: 2-s2.0-85040235337 (38)
11573/947675 - 2017 -
Development of 1,2,4-oxadiazoles as potent and selective inhibitors of the human deacetylase sirtuin 2: structure-activity relationship, X-ray crystal structure, and anticancer activity Moniot, S; Forgione, M; Lucidi, Alessia; Hailu, Gebremedhin Solomon; Nebbioso, A; Carafa, V; Baratta, F; Altucci, L; Giacché, N; Passeri, D; Pellicciari, R; Mai, Antonello; Steegborn, C; Rotili, Dante - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2344-2360 - issn: 0022-2623 - wos: WOS:000397546000013 (80) - scopus: 2-s2.0-85016147565 (84)
11573/944090 - 2017 -
Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity. Ourailidou, Me; Lenoci, A; Zwergel, Clemens; Rotili, Dante; Mai, Antonello; Dekker, F. J. 4. - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 847-856 - issn: 0968-0896 - wos: WOS:000394201900004 (9) - scopus: 2-s2.0-85008433321 (10)
11573/1418429 - 2017 -
Metabolite profiling of ascidian Styela plicata using LC–MS with multivariate statistical analysis and their antitumor activity Palanisamy, S. K.; Trisciuoglio, D.; Zwergel, C.; Del Bufalo, D.; Mai, A. - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 614-623 - issn: 1475-6366 - wos: WOS:000399579300001 (15) - scopus: 2-s2.0-85015046419 (16)
11573/1027813 - 2017 -
Crystal structures of the mitochondrial deacylase Sirtuin 4 reveal isoform-specific acyl recognition and regulation features. Pannek, M; Simic, Z; Fuszard, M; Meleshin, M; Rotili, D; Mai, A; Schutkowski, M; Steegborn, C. - 01a Articolo in rivista
paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. - - issn: 2041-1723 - wos: WOS:000415262500001 (73) - scopus: 2-s2.0-85034035870 (76)
11573/1017602 - 2017 -
EZH2 inhibitors: a patent review (2014-2016) Stazi, Giulia; Zwergel, Clemens; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare
-London, United Kingdom: Ashley Publications Limited) pp. 797-813 - issn: 1354-3776 - wos: WOS:000405302700004 (37) - scopus: 2-s2.0-85020639378 (39)
11573/1027810 - 2017 -
The relevance of Ki calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor. Wapenaar, H; Van Den Bosch, T; Leus, Ngj; Van Der Wouden, Pe; Eleftheriadis, N; Hermans, J; Hailu, Gs; Rotili, D; Mai, A; Dömling, A; Bischoff, R; Haisma, Hj; Dekker, F. J. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 480-486 - issn: 0223-5234 - wos: WOS:000403993500041 (6) - scopus: 2-s2.0-85019413230 (7)
11573/944091 - 2017 -
Structural basis of sirtuin 6 activation by synthetic small molecules. You, W; Rotili, Dante; Li, Tm; Kambach, C; Meleshin, M; Schutkowski, M; Chua, Kf; Mai, Antonello; Steegborn, C. 1. - 01a Articolo in rivista
paper: ANGEWANDTE CHEMIE. INTERNATIONAL EDITION (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 1007-1011 - issn: 1433-7851 - wos: WOS:000394997200011 (121) - scopus: 2-s2.0-85006998900 (131)
11573/955887 - 2017 -
Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells Zwergel, Clemens; Czepukojc, Brigitte; Evain Bana, Emilie; Xu, Zhanjie; Stazi, Giulia; Mori, Mattia; Patsilinakos, Alexandros; Mai, Antonello; Botta, Bruno; Ragno, Rino; Bagrel, Denise; Kirsch, Gilbert; Meiser, Peter; Jacob, Claus; Montenarh, Mathias; Valente, Sergio - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 316-333 - issn: 0223-5234 - wos: WOS:000401677500027 (25) - scopus: 2-s2.0-85017548581 (27)
11573/884147 - 2016 -
Sirtuin functions and modulation: from chemistry to the clinic Carafa, Vincenzo; Rotili, Dante; Forgione, Mariantonietta; Cuomo, Francesca; Serretiello, Enrica; Hailu, Gebremedhin Solomon; Jarho, Elina; Lahtela Kakkonen, Maija; Mai, Antonello; Altucci, Lucia - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. 1-21 - issn: 1868-7083 - wos: WOS:000376856700001 (288) - scopus: 2-s2.0-84973864104 (304)
11573/884154 - 2016 -
Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells Chano, Tokuhiro; Avnet, Sofia; Kusuzaki, Katsuyuki; Bonuccelli, Gloria; Sonveaux, Pierre; Rotili, Dante; Mai, Antonello; Baldini, Nicola - 01a Articolo in rivista
paper: AMERICAN JOURNAL OF CANCER RESEARCH (Madison, WI: Published by e-Century Publishing Corporation, Madison) pp. 859-875 - issn: 2156-6976 - wos: WOS:000384444300002 (31) - scopus: 2-s2.0-84991518619 (34)
11573/851423 - 2016 -
Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model Di Liddo, Rosa; Valente, Sergio; Taurone, Samanta; Zwergel, Clemens; Marrocco, Biagina; Turchetta, Rosaria; Conconi, Maria Teresa; Scarpa, Carlotta; Bertalot, Thomas; Schrenk, Sandra; Mai, Antonello; Artico, Marco - 01a Articolo in rivista
paper: AUTOIMMUNITY (Amsterdam; New York: Harwood Academic Publishers.) pp. 1-11 - issn: 0891-6934 - wos: (0) - scopus: 2-s2.0-84955134169 (19)
11573/884170 - 2016 -
Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells Di Martile, Marta; Desideri, Marianna; De Luca, Teresa; Gabellini, Chiara; Buglioni, Simonetta; Eramo, Adriana; Sette, Giovanni; Milella, Michele Stanislaw; Rotili, Dante; Mai, Antonello; Carradori, Simone; Secci, Daniela; De Maria, Ruggero; Del Bufalo, Donatella; Trisciuoglio, Daniela - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 11332-11348 - issn: 1949-2553 - wos: WOS:000375678300047 (38) - scopus: 2-s2.0-84962019515 (39)
11573/884122 - 2016 -
Progress in the development of lysine methyltransferase SETD8 inhibitors Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Rescigno, Donatella; Mai, Antonello; Castellano, Sabrina; Sbardella, Gianluca - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1680-1685 - issn: 1860-7179 - wos: WOS:000383579700002 (16) - scopus: 2-s2.0-84983335802 (17)
11573/931824 - 2016 -
MC1568 inhibits HDAC6/8 activity and influenza A virus replication in lung epithelial cells: Role of Hsp90 acetylation Panella, Simona; Marcocci, Maria Elena; Celestino, Ignacio; Valente, Sergio; Zwergel, Clemens; Li Puma, Domenica Donatella; Nencioni, Lucia; Mai, Antonello; Palamara, Anna Teresa; Simonetti, Giovanna - 01a Articolo in rivista
paper: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 2017-2031 - issn: 1756-8919 - wos: WOS:000386339500004 (30) - scopus: 2-s2.0-84994010342 (33)
11573/894534 - 2016 -
Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features Speranzini, Valentina; Rotili, Dante; Ciossani, Giuseppe; Pilotto, Simona; Marrocco, Biagina; Forgione, Mariantonietta; Lucidi, Alessia; Forneris, Federico; Mehdipour, Parinaz; Velankar, Sameer; Mai, Antonello; Mattevi, Andrea - 01a Articolo in rivista
paper: SCIENCE ADVANCES (Washington, DC : American Association for the Advancement of Science, 2015-) pp. - - issn: 2375-2548 - wos: WOS:000383734400025 (59) - scopus: 2-s2.0-85020596495 (60)
11573/870518 - 2016 -
LSD1 inhibitors: a patent review (2010-2015) Stazi, Giulia; Zwergel, Clemens; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare
-London, United Kingdom: Ashley Publications Limited) pp. 565-580 - issn: 1354-3776 - wos: WOS:000374900000003 (47) - scopus: 2-s2.0-84961644830 (48)
11573/1147226 - 2016 -
The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery Stunnenberg, Hendrik G.; Abrignani, Sergio; Adams, David; De Almeida, Melanie; Altucci, Lucia; Amin, Viren; Amit, Ido; Antonarakis, Stylianos E.; Aparicio, Samuel; Arima, Takahiro; Arrigoni, Laura; Arts, Rob; Asnafi, Vahid; Badosa, Manel Esteller; Bae, Jae-Bum; Bassler, Kevin; Beck, Stephan; Berkman, Benjamin; Bernstein, Bradley E.; Bilenky, Mikhail; Bird, Adrian; Bock, Christoph; Boehm, Bernhard; Bourque, Guillaume; Breeze, Charles E.; Brors, Benedikt; Bujold, David; Burren, Oliver; Bussemakers, Marion J.; Butterworth, Adam; Campo, Elias; Carrillo-De-Santa-Pau, Enrique; Chadwick, Lisa; Chan, Kui Ming; Chen, Wei; Cheung, Tom H.; Chiapperino, Luca; Choi, Nak Hyen; Chung, Ho-Ryun; Clarke, Laura; Connors, Joseph M.; Cronet, Philippe; Danesh, John; Dermitzakis, Manolis; Drewes, Gerard; Durek, Pawel; Dyke, Stephanie; Dylag, Tomasz; Eaves, Connie J.; Ebert, Peter; Eils, Roland; Eils, Jürgen; Ennis, Catherine A.; Enver, Tariq; Feingold, Elise A.; Felder, Bärbel; Ferguson-Smith, Anne; Fitzgibbon, Jude; Flicek, Paul; Foo, Roger S. -Y.; Fraser, Peter; Frontini, Mattia; Furlong, Eileen; Gakkhar, Sitanshu; Gasparoni, Nina; Gasparoni, Gilles; Geschwind, Daniel H.; Glažar, Petar; Graf, Thomas; Grosveld, Frank; Guan, Xin-Yuan; Guigo, Roderic; Gut, Ivo G.; Hamann, Alf; Han, Bok-Ghee; Harris, R. Alan; Heath, Simon; Helin, Kristian; Hengstler, Jan G.; Heravi-Moussavi, Alireza; Herrup, Karl; Hill, Steven; Hilton, Jason A.; Hitz, Benjamin C.; Horsthemke, Bernhard; Hu, Ming; Hwang, Joo-Yeon; Ip, Nancy Y.; Ito, Takashi; Javierre, Biola-Maria; Jenko, Sasa; Jenuwein, Thomas; Joly, Yann; Jones, Steven J. M.; Kanai, Yae; Kang, Hee Gyung; Karsan, Aly; Kiemer, Alexandra K.; Kim, Song Cheol; Kim, Bong-Jo; Kim, Hyeon-Hoe; Kimura, Hiroshi; Kinkley, Sarah; Klironomos, Filippos; Koh, In-Uk; Kostadima, Myrto; Kressler, Christopher; Kreuzhuber, Roman; Kundaje, Anshul; Küppers, Ralf; Larabell, Carolyn; Lasko, Paul; Lathrop, Mark; Lee, Daniel H. S.; Lee, Suman; Lehrach, Hans; Leitão, Elsa; Lengauer, Thomas; Lernmark, Åke; Leslie, R. David; Leung, Gilberto K. K.; Leung, Danny; Loeffler, Markus; Ma, Yussanne; Mai, Antonello; Manke, Thomas; Marcotte, Eric R.; Marra, Marco A.; Martens, Joost H. A.; Martin-Subero, Jose Ignacio; Maschke, Karen; Merten, Christoph; Milosavljevic, Aleksandar; Minucci, Saverio; Mitsuyama, Totai; Moore, Richard A.; Müller, Fabian; Mungall, Andrew J.; Netea, Mihai G.; Nordström, Karl; Norstedt, Irene; Okae, Hiroaki; Onuchic, Vitor; Ouellette, Francis; Ouwehand, Willem; Pagani, Massimiliano; Pancaldi, Vera; Pap, Thomas; Pastinen, Tomi; Patel, Ronak; Paul, Dirk S.; Pazin, Michael J.; Pelicci, Pier Giuseppe; Phillips, Anthony G.; Polansky, Julia; Porse, Bo; Pospisilik, J. Andrew; Prabhakar, Shyam; Procaccini, Dena C.; Radbruch, Andreas; Rajewsky, Nikolaus; Rakyan, Vardham; Reik, Wolf; Ren, Bing; Richardson, David; Richter, Andreas; Rico, Daniel; Roberts, David J.; Rosenstiel, Philip; Rothstein, Mark; Salhab, Abdulrahman; Sasaki, Hiroyuki; Satterlee, John S.; Sauer, Sascha; Schacht, Claudia; Schmidt, Florian; Schmitz, Gerd; Schreiber, Stefan; Schröder, Christopher; Schübeler, Dirk; Schultze, Joachim L.; Schulyer, Ronald P.; Schulz, Marcel; Seifert, Martin; Shirahige, Katsuhiko; Siebert, Reiner; Sierocinski, Thomas; Siminoff, Laura; Sinha, Anupam; Soranzo, Nicole; Spicuglia, Salvatore; Spivakov, Mikhail; Steidl, Christian; Strattan, J. Seth; Stratton, Michael; Südbeck, Peter; Sun, Hao; Suzuki, Narumi; Suzuki, Yutaka; Tanay, Amos; Torrents, David; Tyson, Frederick L.; Ulas, Thomas; Ullrich, Sebastian; Ushijima, Toshikazu; Valencia, Alfonso; Vellenga, Edo; Vingron, Martin; Wallace, Chris; Wallner, Stefan; Walter, Jörn; Wang, Huating; Weber, Stephanie; Weiler, Nina; Weller, Andreas; Weng, Andrew; Wilder, Steven; Wiseman, Sam M.; Wu, Angela R.; Wu, Zhenguo; Xiong, Jieyi; Yamashita, Yasuhiro; Yang, Xinyi; Yap, Desmond Y.; Yip, Kevin Y.; Yip, Stephen; Yoo, Jae-Il; Zerbino, Daniel; Zipprich, Gideon; Hirst, Martin - 01a Articolo in rivista
paper: CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 1145-1149 - issn: 0092-8674 - wos: WOS:000389470100004 (272) - scopus: 2-s2.0-84995912090 (312)
11573/870523 - 2016 -
1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells Valente, Sergio; Mellini, Paolo; Spallotta, Francesco; Carafa, Vincenzo; Nebbioso, Angela; Polletta, Lucia; Carnevale, Ilaria; Saladini, Serena; Trisciuoglio, Daniela; Gabellini, Chiara; Tardugno, Maria; Zwergel, Clemens; Cencioni, Chiara; Atlante, Sandra; Moniot, Sébastien; Steegborn, Clemens; Budriesi, Roberta; Tafani, Marco; Del Bufalo, Donatella; Altucci, Lucia; Gaetano, Carlo; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1471-1491 - issn: 0022-2623 - wos: WOS:000371103600016 (59) - scopus: 2-s2.0-84959335947 (63)
11573/884171 - 2016 -
The histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases Van Den Bosch, Thea; Boichenko, Alexander; Leus, Niek G. J.; Ourailidou, Maria E.; Wapenaar, Hannah; Rotili, Dante; Mai, Antonello; Imhof, Axel; Bischoff, Rainer; Haisma, Hidde J.; Dekker, Frank J. - 01a Articolo in rivista
paper: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited
-London ; New York : Pergamon Press, 1958-) pp. 130-140 - issn: 0006-2952 - wos: WOS:000371446300011 (41) - scopus: 2-s2.0-84958753301 (51)
11573/856751 - 2016 -
Discovery of a novel inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) as orally active antitumor agent Vianello, Paola; Botrugno, Oronza A; Cappa, Anna; Dal Zuffo, Roberto; Dessanti, Paola; Mai, Antonello; Marrocco, Biagina; Mattevi, Andrea; Meroni, Giuseppe; Minucci, Saverio; Stazi, Giulia; Thaler, Florian; Trifiró, Paolo; Valente, Sergio; Villa, Manuela; Varasi, Mario; Mercurio, Ciro - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1501-1517 - issn: 0022-2623 - wos: WOS:000371103600018 (66) - scopus: 2-s2.0-84959421233 (68)
11573/870553 - 2016 -
DNA methyltransferases Inhibitors from natural sources Zwergel, Clemens; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: CURRENT TOPICS IN MEDICINAL CHEMISTRY (Hilversum : Bentham Science Publishers) pp. 680-696 - issn: 1568-0266 - wos: WOS:000364586000004 (50) - scopus: 2-s2.0-84983215072 (57)
11573/884227 - 2015 -
Identification of structural features of 2-alkylidene-1,3-dicarbonyl derivatives that induce inhibition and/or activation of histone acetyltransferases KAT3B/p300 and KAT2B/PCAF Castellano, Sabrina; Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Mai, Antonello; Novellino, Ettore; Tosco, Alessandra; Sbardella, Gianluca - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 144-157 - issn: 1860-7179 - wos: WOS:000346766700014 (18) - scopus: 2-s2.0-84919779703 (22)
11573/884213 - 2015 -
Sirtuin function in aging heart and vessels Cencioni, Chiara; Spallotta, Francesco; Mai, Antonello; Martelli, Fabio; Farsetti, Antonella; Zeiher, Andreas M.; Gaetano, Carlo - 01a Articolo in rivista
paper: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 55-61 - issn: 0022-2828 - wos: WOS:000356839100007 (75) - scopus: 2-s2.0-84937970546 (81)
11573/884205 - 2015 -
A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts De Luca, Anastasia; Rotili, Dante; Carpanese, Debora; Lenoci, Alessia; Calderan, Laura; Scimeca, Manuel; Mai, Antonello; Bonanno, Elena; Rosato, Antonio; Geroni, Cristina; Quintieri, Luigi; Caccuri, Anna Maria - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 4126-4143 - issn: 1949-2553 - wos: WOS:000352696200052 (26) - scopus: 2-s2.0-84924251939 (27)
11573/884185 - 2015 -
Chronic stress and antidepressant induced changes in Hdac5 and Sirt2 affect synaptic plasticity Erburu, M.; Muñoz Cobo, I.; Domínguez Andrés, J.; Beltran, E.; Suzuki, T.; Mai, Antonello; Valente, Sergio; Puerta, E.; Tordera, R. M. - 01a Articolo in rivista
paper: EUROPEAN NEUROPSYCHOPHARMACOLOGY (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 2036-2048 - issn: 0924-977X - wos: WOS:000369152500020 (53) - scopus: 2-s2.0-84947494371 (56)
11573/784167 - 2015 -
Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells G., Di Pompo; M., Salerno; Rotili, Dante; Valente, Sergio; Zwergel, Clemens; S., Avnet; G., Lattanzi; N., Baldini; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4073-4079 - issn: 0022-2623 - wos: WOS:000354911200031 (55) - scopus: 2-s2.0-84929378676 (56)
11573/884194 - 2015 -
A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib Graziani, Grazia; Artuso, Simona; De Luca, Anastasia; Muzi, Alessia; Rotili, Dante; Scimeca, Manuel; Atzori, Maria Grazia; Ceci, Claudia; Mai, Antonello; Leonetti, Carlo; Levati, Lauretta; Bonanno, Elena; Tentori, Lucio; Caccuri, Anna Maria - 01a Articolo in rivista
paper: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited
-London ; New York : Pergamon Press, 1958-) pp. 16-27 - issn: 0006-2952 - wos: WOS:000353858800002 (30) - scopus: 2-s2.0-84930886228 (31)
11573/884225 - 2015 -
New insights on the mechanism of quinoline-based DNA methyltransferase inhibitors Gros, Christina; Fleury, Laurence; Nahoum, Virginie; Faux, Céline; Valente, Sergio; Labella, Donatella; Cantagrel, Frédéric; Rilova, Elodie; Bouhlel, Mohamed Amine; David Cordonnier, Marie Hélène; Dufau, Isabelle; Ausseil, Frédéric; Mai, Antonello; Mourey, Lionel; Lacroix, Laurent; Arimondo, Paola B. - 01a Articolo in rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 6293-6302 - issn: 0021-9258 - wos: WOS:000350732500035 (47) - scopus: 2-s2.0-84924897991 (52)
11573/870559 - 2015 -
Abstract 2946: Effects of two novel quinoline-based non-nucleoside DNA methyltransferase inhibitors against bone sarcomas Manara, Maria Cristina; Valente, Sergio; Cristalli, Camilla; Baricordi, Cristina; Zwergel, Clemens; Arimondo, Paola B; Picci, Piero; Mai, Antonello; Scotlandi, Katia - 04d Abstract in atti di convegno
paper: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 2946-2946 - issn: 0008-5472 - wos: WOS:000371578506091 (0) - scopus: (0)
11573/884196 - 2015 -
A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach Milite, Ciro; Feoli, Alessandra; Sasaki, Kazuki; La Pietra, Valeria; Balzano, Amodio Luca; Marinelli, Luciana; Mai, Antonello; Novellino, Ettore; Castellano, Sabrina; Tosco, Alessandra; Sbardella, Gianluca - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2779-2798 - issn: 0022-2623 - wos: WOS:000351971800013 (44) - scopus: 2-s2.0-84925957014 (47)
11573/856754 - 2015 -
Discovery of inhibitors for the ether lipid-generating enzyme AGPS as anti-cancer agents Piano, Valentina; Benjamin, Daniel I.; Valente, Sergio; Nenci, Simone; Marrocco, Biagina; Mai, Antonello; Aliverti, Alessandro; Nomura, Daniel K; Mattevi, Andrea - 01a Articolo in rivista
paper: ACS CHEMICAL BIOLOGY (AMERICAN CHEMICAL SOCiety, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036) pp. 2589-2597 - issn: 1554-8929 - wos: WOS:000365462700020 (49) - scopus: 2-s2.0-84947909618 (49)
11573/789900 - 2015 -
SIRT5 regulation of ammonia-induced autophagy and mitophagy Polletta, Lucia; Vernucci, Enza; Carnevale, Ilaria; Arcangeli, Tania; Rotili, Dante; Palmerio, Silvia; Steegborn, Clemens; Nowak, Theresa; Schutkowski, Mike; Pellegrini, Laura; Sansone, Luigi; Villanova, Lidia; Runci, Alessandra; Pucci, Bruna; Morgante, Emanuela; Fini, Massimo; Mai, Antonello; Russo, Matteo A; Tafani, Marco - 01a Articolo in rivista
paper: AUTOPHAGY (Landes Bioscience Georgetown TX 78628) pp. 253-270 - issn: 1554-8627 - wos: WOS:000352778700007 (231) - scopus: 2-s2.0-84943265499 (236)
11573/680651 - 2015 -
Synthesis and structure-activity relationship of new cytotoxic agents targeting human glutathione-S-transferases. Rotili, Dante; De Luca, A; Tarantino, D; Pezzola, S; Forgione, Mariantonietta; Morozzo Della Rocca, B; Falconi, M; Mai, Antonello; Caccuri, A. M. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 156-171 - issn: 0223-5234 - wos: WOS:000348003500017 (32) - scopus: 2-s2.0-84908450815 (34)
11573/784164 - 2015 -
Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation S., Pilotto; V., Speranzini; M., Tortorici; D., Durand; A., Fish; Valente, Sergio; F., Forneris; Mai, Antonello; T. K., Sixma; P., Vachette; A., Mattevi - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 2752-2757 - issn: 0027-8424 - wos: WOS:000350224900048 (71) - scopus: 2-s2.0-84924368105 (74)
11573/781696 - 2015 -
Pure diastereomers of a tranylcypromine-based LSD1 inhibitor: enzyme selectivity and in-cell studies Valente, Sergio; Veronica, Rodriguez; Ciro, Mercurio; Paola, Vianello; Bruna, Saponara; Roberto, Cirilli; Giuseppe, Ciossani; Labella, Donatella; Marrocco, Biagina; Ruoppolo, Giovanni; Oronza A., Botrugno; Paola, Dessanti; Saverio, Minucci; Andrea, Mattevi; Mario, Varasi; Mai, Antonello - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 173-177 - issn: 1948-5875 - wos: WOS:000349652000012 (21) - scopus: 2-s2.0-84922867052 (18)
11573/781693 - 2015 -
Pure enantiomers of benzoylamino-tranylcypromine: LSD1 inhibition, gene modulation in human leukemia cells and effects on clonogenic potential of murine promyelocytic blasts Valente, Sergio; Veronica, Rodriguez; Mercurio, Ciro; Vianello, Paola; Saponara, Bruna; Cirilli, Roberto; Ciossani, Giuseppe; Labella, Donatella; Marrocco, Biagina; Monaldi, Daria; Ruoppolo, Giovanni; Tilset, Mats; Botrugno, Oronza A.; Dessanti, Paola; Minucci, Saverio; Mattevi, Andrea; Varasi, Mario; Mai, Antonello - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 163-174 - issn: 0223-5234 - wos: WOS:000353730900016 (27) - scopus: 2-s2.0-84924406877 (30)
11573/779609 - 2015 -
Pyrrole- and indole-containing tranylcypromine derivatives as novel lysine-specific demethylase 1 inhibitors active on cancer cells. Veronica, Rodriguez; Valente, Sergio; Stefano, Rovida; Rotili, Dante; Stazi, Giulia; Lucidi, Alessia; Giuseppe, Ciossani; Andrea, Mattevi; Oronza A., Botrugno; Paola, Dessanti; Ciro, Mercurio; Paola, Vianello; Saverio, Minucci; Mario, Varasi; Mai, Antonello - 01a Articolo in rivista
paper: MEDCHEMCOMM (Cambridge : Royal Society of Chemistry, 2010-) pp. 665-670 - issn: 2040-2503 - wos: WOS:000352903400023 (22) - scopus: 2-s2.0-84928004801 (24)
11573/884188 - 2015 -
Targeting lysine deacetylases (KDACs) in parasites Wang, Qi; Rosa, Bruce A.; Nare, Bakela; Powell, Kerrie; Valente, Sergio; Rotili, Dante; Mai, Antonello; Marshall, Garland R.; Mitreva, Makedonka - 01a Articolo in rivista
paper: PLOS NEGLECTED TROPICAL DISEASES (San Francisco, CA : Public Library of Science) pp. e000426- - issn: 1935-2727 - wos: WOS:000363031200020 (40) - scopus: 2-s2.0-84943193825 (43)
11573/884182 - 2015 -
Enzyme kinetics and inhibition of histone acetyltransferase KAT8 Wapenaar, Hannah; Van Der Wouden, Petra E; Groves, Matthew R; Rotili, Dante; Mai, Antonello; Dekker, Frank J. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ([Paris] : Elsevier, [198?]-) pp. 289-296 - issn: 1768-3254 - wos: WOS:000364891400020 (28) - scopus: 2-s2.0-84945264596 (30)
11573/870535 - 2015 -
Emerging approaches for histone deacetylase inhibitor drug discovery Zwergel, Clemens; Valente, Sergio; Jacob, Claus; Mai, Antonello - 01a Articolo in rivista
paper: EXPERT OPINION ON DRUG DISCOVERY (--London United Kingdom:Informa Healthcare
-London : Informa Healthcare, 2006-.) pp. 599-613 - issn: 1746-0441 - wos: WOS:000355006600004 (63) - scopus: 2-s2.0-84929928202 (70)
11573/557642 - 2014 -
Reversible acetylation regulates vascular endothelial growth factor receptor-2 activity A., Zecchin; L., Pattarini; M. I., Gutierrez; M., Mano; Mai, Antonello; Valente, Sergio; M. P., Myers; S., Pantano; M., Giacca - 01a Articolo in rivista
paper: JOURNAL OF MOLECULAR CELL BIOLOGY (Shanghai : Journal of Molecular Cell Biology Editorial Office Oxford University Press) pp. 116-127 - issn: 1674-2788 - wos: WOS:000336081100003 (30) - scopus: 2-s2.0-84899675551 (32)
11573/1155213 - 2014 -
Sirtuins blunt reactive gliosis in an in vitro model of Alzheimer’s disease. Bronzuoli, Maria Rosanna; Scuderi, Caterina; Stecca, Claudia; Rotili, Dante; Valente, Sergio; Cugno, Michele; Mai, Antonello; Steardo, Luca. - 04d Abstract in atti di convegno
conference: 17° Simposio SIF Dottorandi, Assegnisti di Ricerca Postdottorandi e Specializzandi in Farmacologia e Scienze Affini (Rimini)
book: 17° Simposio SIF Dottorandi, Assegnisti di Ricerca Postdottorandi e Specializzandi in Farmacologia e Scienze Affini. - ()
11573/665415 - 2014 -
Novel inhibitors of human histone deacetylases: Design, synthesis and bioactivity of 3-alkenoylcoumarines C., Seidel; M., Schnekenburger; Zwergel, Clemens; F., Gaascht; Mai, Antonello; M., Dicato; G., Kirsch; Valente, Sergio; M., Diederich - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 3797-3801 - issn: 0960-894X - wos: WOS:000340565900024 (43) - scopus: 2-s2.0-84905916821 (48)
11573/685071 - 2014 -
Evaluation of a large library of (thiazol-2-yl)hydrazones and analogues as histone acetyltransferase inhibitors: Enzyme and cellular studies. Carradori, S; Rotili, Dante; De Monte, Celeste; Lenoci, A; D'ascenzio, M; Rodriguez, V; Filetici, Patrizia; Miceli, M; Nebbioso, A; Altucci, L; Secci, Daniela; Mai, Antonello - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 569-578 - issn: 0223-5234 - wos: WOS:000337985400049 (49) - scopus: 2-s2.0-84900559630 (56)
11573/557645 - 2014 -
Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS Ciarapica, R.; Carcarino, E.; Adesso, L.; De Salvo, Maria; Bracaglia, G.; Leoncini, P. P.; Dall'agnese, A.; Verginelli, F.; Milano, G. M.; Boldrini, R.; Inserra, A.; Stifani, S.; Screpanti, Isabella; Marquez, V. E.; Valente, Sergio; Mai, Antonello; Puri, P. L.; Locatelli, F.; Palacios, D.; Rota, R. - 01a Articolo in rivista
paper: BMC CANCER (London: BioMed Central, [2001]-) pp. 139- - issn: 1471-2407 - wos: WOS:000332528100001 (51) - scopus: 2-s2.0-84898597003 (58)
11573/670458 - 2014 -
The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx) Ciarapica, R.; De Salvo, Maria; Carcarino, E.; Bracaglia, G.; Adesso, Laura; Leoncini, P. P.; Dall'agnese, A.; Walters, Z. S.; Verginelli, F.; De Sio, L.; Boldrini, R.; Inserra, A.; Bisogno, G.; Rosolen, A.; Alaggio, R.; Ferrari, A.; Collini, P.; Locatelli, M.; Stifani, S.; Screpanti, Isabella; Rutella, S.; Yu, Q.; Marquez, V. E.; Shipley, J.; Valente, Sergio; Mai, Antonello; Miele, L.; Puri, P. L.; Locatelli, F.; Palacios, D.; Rota, R. - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 4173-4184 - issn: 0950-9232 - wos: WOS:000340595700008 (56) - scopus: 2-s2.0-84905868284 (61)
11573/884235 - 2014 -
Histone modifications, stem cells and prostate cancer Crea, Francesco; Clermont, Pier Luc; Mai, Antonello; Helgason, Cheryl D. - 01a Articolo in rivista
paper: CURRENT PHARMACEUTICAL DESIGN (Hilversum : Bentham Science Publishers) pp. 1687-97- - issn: 1873-4286 - wos: WOS:000334311500012 (11) - scopus: 2-s2.0-84903744315 (11)
11573/556419 - 2014 -
Context-Selective Death of Acute Myeloid Leukemia Cells Triggered by the Novel Hybrid Retinoid-HDAC Inhibitor MC2392. De Bellis, F; Carafa, V; Conte, M; Rotili, Dante; Petraglia, F; Matarese, F; Françoijs, Kj; Ablain, J; Valente, Sergio; Castellano, R; Goubard, A; Collette, Y; Mandoli, A; Martens, Jh; De Thé, H; Nebbioso, A; Mai, Antonello; Stunnenberg, Hg; Altucci, L. - 01a Articolo in rivista
paper: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 2328-2339 - issn: 0008-5472 - wos: WOS:000334584200020 (28) - scopus: 2-s2.0-84899541163 (33)
11573/884228 - 2014 -
Dissecting histone deacetylase role in pulmonary arterial smooth muscle cell proliferation and migration Galletti, Margherita; Cantoni, Silvia; Zambelli, Filippo; Valente, Sabrina; Palazzini, Massimiliano; Manes, Alessandra; Pasquinelli, Gianandrea; Mai, Antonello; Galiè, Nazzareno; Ventura, Carlo - 01a Articolo in rivista
paper: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited
-London ; New York : Pergamon Press, 1958-) pp. 181-190 - issn: 0006-2952 - wos: WOS:000341070800006 (25) - scopus: 2-s2.0-84906791178 (27)
11573/664054 - 2014 -
PRMT1 arginine methyltransferase accumulates in cytoplasmic bodies that respond to selective inhibition and DNA damage J., Suchánková; S., Legartová; P., Sehnalová; S., Kozubek; Valente, Sergio; Labella, Donatella; Mai, Antonello; C., Eckerich; F. O., Fackelmayer; D. V., Sorokin; E., Bártová - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF HISTOCHEMISTRY (Pavia : PagePress Publications, 2010) pp. 139-151 - issn: 2038-8306 - wos: WOS:000338624700013 (10) - scopus: 2-s2.0-84899705373 (9)
11573/556417 - 2014 -
Quinoline-based p300 histone acetyltransferase inhibitors with pro-apoptotic activity in human leukemia U937 cells. Lenoci, Alessia; Tomassi, S; Conte, M; Benedetti, R; Rodriguez, V; Carradori, Simone; Secci, Daniela; Castellano, S; Sbardella, G; Filetici, P; Novellino, E; Altucci, L; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 542-548 - issn: 1860-7187 - wos: WOS:000331795500010 (26) - scopus: 2-s2.0-84896698147 (27)
Mai, Antonello - 01m Editorial/Introduzione in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 415-417 - issn: 1860-7179 - wos: (0) - scopus: 2-s2.0-84896725631 (12)
11573/665613 - 2014 -
Sirtuin modulators: an updated patent review (2012 - 2014) P., Mellini; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare
-London, United Kingdom: Ashley Publications Limited) pp. 5-15 - issn: 1354-3776 - wos: WOS:000346742700002 (48) - scopus: 2-s2.0-84919458504 (50)
11573/665612 - 2014 -
Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: A novel class of irreversible inhibitors of histone demethylase KDM1A P., Vianello; O. A., Botrugno; A., Cappa; G., Ciossani; P., Dessanti; Mai, Antonello; A., Mattevi; G., Meroni; S., Minucci; F., Thaler; M., Tortorici; P., Trifiró; Valente, Sergio; M., Villa; M., Varasi; C., Mercurio - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 352-363 - issn: 0223-5234 - wos: WOS:000343781800032 (49) - scopus: 2-s2.0-84906839626 (48)
11573/542432 - 2014 -
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities Rotili, Dante; Stefano, Tomassi; Mariarosaria, Conte; Rosaria, Benedetti; Marcello, Tortorici; Giuseppe, Ciossani; Valente, Sergio; Marrocco, Biagina; Labella, Donatella; Ettore, Novellino; Andrea, Mattevi; Lucia, Altucci; Tumber, Anthony; Yapp, Clarence; N. F., King Oliver; Richard J., Hopkinson; Akane, Kawamura; J., Schofield Christopher; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 42-55 - issn: 0022-2623 - wos: WOS:000329677800004 (96) - scopus: 2-s2.0-84892565144 (105)
11573/681257 - 2014 -
Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity. Rotili, Dante; Tarantino, D; Marrocco, Biagina; Gros, C; Masson, V; Poughon, V; Ausseil, F; Chang, Y; Labella, D; Cosconati, S; Di Maro, S; Novellino, E; Schnekenburger, M; Grandjenette, C; Bouvy, C; Diederich, M; Cheng, X; Arimondo, Pb; Mai, Antonello - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. - - issn: 1932-6203 - wos: WOS:000338213300096 (32) - scopus: 2-s2.0-84901487126 (35)
11573/681252 - 2014 -
Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes Rotili, Dante; Tarantino, D; Nawrozkij, Mb; Babushkin, As; Botta, G; Marrocco, Biagina; Cirilli, R; Menta, Sergio; Badia, R; Crespan, E; Ballante, Flavio; Ragno, Rino; Esté, Ja; Maga, G; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5212-5225 - issn: 0022-2623 - wos: WOS:000338184100018 (18) - scopus: 2-s2.0-84903515653 (18)
11573/643824 - 2014 -
Sirtuin modulators control reactive gliosis in an in vitro model of alzheimer's disease Scuderi, Caterina; Stecca, Claudia; Bronzuoli, Maria Rosanna; Rotili, Dante; Valente, Sergio; Mai, Antonello; Steardo, Luca - 01a Articolo in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000347086800001 (52) - scopus: 2-s2.0-84904631078 (56)
11573/553541 - 2014 -
I kappa B kinase (IKK)-epsilon targets interferon regulatory factor 1 in activated T lymphocytes. Sgarbanti, M; Marsili, G; Remoli, Al; Stellacci, E; Mai, Antonello; Rotili, Dante; Perrotti, E; Acchioni, C; Orsatti, R; Iraci, N; Ferrari, M; Borsetti, A; Hiscott, J; Battistini, A. - 01a Articolo in rivista
paper: MOLECULAR AND CELLULAR BIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 1054-1065 - issn: 0270-7306 - wos: WOS:000331995800012 (28) - scopus: 2-s2.0-84894284462 (30)
11573/664060 - 2014 -
1,3,4-Oxadiazole-Containing Histone Deacetylase Inhibitors: Anticancer Activities in Cancer Cells Valente, Sergio; D., Trisciuoglio; T., De Luca; A., Nebbioso; Labella, Donatella; Lenoci, Alessia; C., Bigogno; G. M., Dondio; M., Miceli; G., Brosch; D., Del Bufalo; L., Altucci; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6259-6265 - issn: 0022-2623 - wos: WOS:000339540800033 (124) - scopus: 2-s2.0-84904962606 (127)
11573/664047 - 2014 -
Small-molecule inhibitors of histone deacetylase for the treatment of cancer and non-cancer diseases: a patent review (2011 - 2013). Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare
-London, United Kingdom: Ashley Publications Limited) pp. 401-415 - issn: 1354-3776 - wos: WOS:000333098200003 (45) - scopus: 2-s2.0-84896470334 (45)
11573/547528 - 2014 -
Selective Non-nucleoside Inhibitors of Human DNA Methyltransferases Active in Cancer Including in Cancer Stem Cells Valente, Sergio; Yiwei, Liu; Michael, Schnekenburger; Zwergel, Clemens; Sandro, Cosconati; Christina, Gros; Maria, Tardugno; Donatella, Labella; Cristina, Florean; Steven, Minden; Hideharu, Hashimoto; Yanqi, Chang; Xing, Zhang; Gilbert, Kirsch; Ettore, Novellino; Paola B., Arimondo; Miele, Evelina; Ferretti, Elisabetta; Gulino, Alberto; Marc, Diederich; Xiaodong, Cheng; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 701-713 - issn: 0022-2623 - wos: WOS:000331493000013 (107) - scopus: 2-s2.0-84894065301 (116)
11573/884229 - 2014 -
Identification of NuRSERY, a new functional HDAC complex composed by HDAC5, GATA1, EKLF and pERK present in human erythroid cells Varricchio, Lilian; Dell'aversana, Carmela; Nebbioso, Angela; Migliaccio, Giovanni; Altucci, Lucia; Mai, Antonello; Grazzini, Giuliano; Bieker, James J.; Migliaccio, Anna Rita - 01a Articolo in rivista
paper: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 112-122 - issn: 1357-2725 - wos: WOS:000335611500016 (25) - scopus: 2-s2.0-84896531605 (31)
11573/884231 - 2014 -
The histone acetylase activator pentadecylidenemalonate 1b rescues proliferation and differentiation in the human cardiac mesenchymal cells of type 2 diabetic patients Vecellio, Matteo; Spallotta, Francesco; Nanni, Simona; Colussi, Claudia; Cencioni, Chiara; Derlet, Anja; Bassetti, Beatrice; Tilenni, Manuela; Carena, Maria Cristina; Farsetti, Antonella; Sbardella, Gianluca; Castellano, Sabrina; Mai, Antonello; Martelli, Fabio; Pompilio, Giulio; Capogrossi, Maurizio C.; Rossini, Alessandra; Dimmeler, Stefanie; Zeiher, Andreas; Gaetano, Carlo - 01a Articolo in rivista
paper: DIABETES (American Diabetes Association:National Service Center, 1701 North Beaureguard Street:Alexandria, VA 22311:(800)232-3472, (703)549-1500, INTERNET: http://www.diabetes.org/diabetscare, Fax: (703)549-6995) pp. 2132-2147 - issn: 0012-1797 - wos: WOS:000336643900037 (60) - scopus: 2-s2.0-84899824083 (63)
11573/513469 - 2013 -
A Nitric Oxide-dependent crosstalk between class I and III Histone Deacetylases accelerates skin repair. 2. Spallotta, F.; Cencioni, C.; Straino, S.; Nanni, S.; Rosati, J.; Artuso, S.; Manni, I.; Colussi, C.; Piaggio, G.; Martelli, F.; Valente, Sergio; Mai, Antonello; Capogrossi, M. C.; Farsetti, A.; Gaetano, C. - 01a Articolo in rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 11004-11012 - issn: 0021-9258 - wos: WOS:000317915500007 (66) - scopus: 2-s2.0-84876580701 (72)
11573/525990 - 2013 -
Oxidative stress and epigenetic regulation in ageing and age-related diseases Chiara, Cencioni; Spallotta, Francesco; Fabio, Martelli; Valente, Sergio; Mai, Antonello; Zeiher Am, Gaetano C. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 17643-17663 - issn: 1661-6596 - wos: WOS:000328623900021 (154) - scopus: 2-s2.0-84883479431 (180)
11573/513467 - 2013 -
Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue. Galmozzi, A.; Mitro, N.; Ferrari, A.; Gers, E.; Gilardi, F.; Godio, C.; Cermenati, G.; Gualerzi, A.; Donetti, E.; Rotili, Dante; Valente, Sergio; Guerrini, U.; Caruso, D.; Mai, Antonello; Saez, E.; De Fabiani, E.; Crestani, M. - 01a Articolo in rivista
paper: DIABETES (American Diabetes Association:National Service Center, 1701 North Beaureguard Street:Alexandria, VA 22311:(800)232-3472, (703)549-1500, INTERNET: http://www.diabetes.org/diabetscare, Fax: (703)549-6995) pp. 732-742 - issn: 0012-1797 - wos: WOS:000315556400017 (187) - scopus: 2-s2.0-84869106554 (203)
11573/513468 - 2013 -
Class II HDAC Inhibition Hampers Hepatic Stellate Cell Activation by Induction of MicroRNA-29 Inge, Mannaerts; Nathalie, Eysackers; Oscar O., Onyema; Katrien Van, Beneden; Valente, Sergio; Mai, Antonello; Margarete, Odenthal; Leo A., Van Grunsven - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e55786- - issn: 1932-6203 - wos: WOS:000314610600159 (62) - scopus: 2-s2.0-84873122711 (68)
11573/884236 - 2013 -
Screen of pseudopeptidic inhibitors of human sirtuins 1-3: Two lead compounds with antiproliferative effects in cancer cells Mellini, Paolo; Kokkola, Tarja; Suuronen, Tiina; Salo, Heikki S.; Tolvanen, Laura; Mai, Antonello; Lahtela Kakkonen, Maija; Jarho, Elina M. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6681-6695 - issn: 0022-2623 - wos: WOS:000330097400013 (30) - scopus: 2-s2.0-84884225041 (33)
11573/525042 - 2013 -
Detrimental effect of class-selective histone deacetylase inhibitors during tissue regeneration following hindlimb ischemia Spallotta, F.; Silvia, Tardivo; Nanni, S.; Rosati, J. D.; Straino, S.; Mai, Antonello; Vecellio, M.; Valente, Sergio; Capogrossi, M. C.; Farsetti, A.; Martone, Julie; Bozzoni, Irene; Pontecorvi, A.; Gaetano, C.; Colussi, C. - 01a Articolo in rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 22915-22929 - issn: 0021-9258 - wos: WOS:000330598200004 (27) - scopus: 2-s2.0-84881396773 (26)
11573/884239 - 2013 -
Protein recognition by short peptide reversible inhibitors of the chromatin-modifying LSD1/CoREST lysine demethylase Tortorici, Marcello; Borrello, Maria Teresa; Tardugno, Maria; Chiarelli, Laurent R.; Pilotto, Simona; Ciossani, Giuseppe; Vellore, Nadeem A.; Bailey, Sarah G.; Cowan, Jonathan; O'connell, Maria; Crabb, Simon J.; Packham, Graham; Mai, Antonello; Baron, Riccardo; Ganesan, A.; Mattevi, Andrea - 01a Articolo in rivista
paper: ACS CHEMICAL BIOLOGY (AMERICAN CHEMICAL SOCiety, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036) pp. 1677-1682 - issn: 1554-8929 - wos: WOS:000323363000004 (59) - scopus: 2-s2.0-84880777273 (61)
11573/514588 - 2013 -
tert-Butylcarbamate-Containing Histone Deacetylase Inhibitors: Apoptosis Induction, Cytodifferentiation, and Antiproliferative Activities in Cancer Cells. Valente, Sergio; Trisciuoglio, D; Tardugno, M; Benedetti, R; Labella, Donatella; Secci, Daniela; Mercurio, C; Boggio, R; Tomassi, S; Di Maro, S; Novellino, E; Altucci, L; Del Bufalo, D; Mai, Antonello; Cosconati, S. - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. - - issn: 1860-7179 - wos: WOS:000318245300013 (16) - scopus: 2-s2.0-84877064105 (18)
11573/525043 - 2013 -
Reactivity of 4-vinyl-2H-1-benzopyran-2-ones in diels-alder cycloaddition reactions: Access to coumarin-based polycycles with Cdc25 phosphatase-inhibiting activity Valente, Sergio; Zhanjie, Xu; Emilie, Bana; Zwergel, Clemens; Mai, Antonello; Jacob, Claus; Peter, Meiser; Denyse, Bagrel; Artur M. S., Silva; Kirsch, Gilbert - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 2869-2877 - issn: 1434-193X - wos: WOS:000318803200018 (11) - scopus: 2-s2.0-84877688906 (12)
11573/870542 - 2013 -
Novel benzofuran-chromone and -coumarin derivatives: Synthesis and biological activity in K562 human leukemia cells Zwergel, Clemens; Valente, Sergio; Salvato, Angela; Xu, Zhanjie; Talhi, Oualid; Mai, Antonello; Silva, Artur; Altucci, Lucia; Kirsch, Gilbert - 01a Articolo in rivista
paper: MEDCHEMCOMM (Cambridge : Royal Society of Chemistry, 2010-) pp. 1571-1579 - issn: 2040-2503 - wos: WOS:000327461300005 (47) - scopus: 2-s2.0-84888154287 (51)
11573/442878 - 2012 -
An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases Anup K., Upadhyay; Rotili, Dante; Ji Woong, Han; Ruogu, Hu; Yanqi, Chang; Donatella, Labella; Xing, Zhang; Young Sup, Yoon; Mai, Antonello; Xiaodong, Cheng - 01a Articolo in rivista
paper: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD,
-London; New York: Academic Press.) pp. 319-327 - issn: 0022-2836 - wos: WOS:000301313600001 (44) - scopus: 2-s2.0-84862777760 (47)
11573/513465 - 2012 -
Identification of Small-Molecule Enhancers of Arginine Methylation Catalyzed by Coactivator-Associated Arginine Methyltransferase 1. Castellano, S.; Spannhoff, A.; Milite, C.; Dal Piaz, F.; Cheng, D.; Tosco, A.; Viviano, M.; Yamani, A.; Cianciulli, A.; Sala, M.; Cura, V.; Cavarelli, J.; Novellino, E.; Mai, Antonello; Bedford, M. T.; Sbardella, G. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9875-9890 - issn: 0022-2623 - wos: WOS:000311461500040 (25) - scopus: 2-s2.0-84869995779 (27)
11573/485037 - 2012 -
P300/CBP associated factor regulates nitroglycerin-dependent arterial relaxation by nε-lysine acetylation of contractile proteins Colussi, C.; Scopece, A.; Vitale, S.; Spallotta, F.; Mattiussi, S.; Rosati, J.; Illi, B.; Mai, Antonello; Castellano, S.; Sbardella, Gianluca; Farsetti, A.; C, Gaetano; Mc, Capogrossi - 01a Articolo in rivista
paper: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY (-PHILADELPHIA, USA: LIPPINCOTT WILLIAMS & WILKINS
-Dallas, TX : The Association, c1995-) pp. 2435-2443 - issn: 1079-5642 - wos: WOS:000308811200013 (28) - scopus: 2-s2.0-84866630451 (28)
11573/485018 - 2012 -
BLUEPRINT to decode the epigenetic signature written in blood. David, Adams; Lucia, Altucci; Stylianos E., Antonarakis; Ballesteros, Juan; Beck, Stephan; Bird, Adrian; Christoph, Bock; Bernhard, Boehm; Elias, Campo; Andrea, Caricasole; Fredrik, Dahl; Emmanouil T., Dermitzakis; Tariq, Enver; Manel, Esteller; Estivill, Xavier; Anne Ferguson, Smith; Fitzgibbon, Jude; Flicek, Paul; Claudia, Giehl; Thomas, Graf; Frank, Grosveld; Roderic, Guigo; Ivo, Gut; Kristian, Helin; Jarvius, Jonas; Ralf, Kuppers; Lehrach, Hans; Thomas, Lengauer; Åke, Lernmark; David Leslie Markus, Loeffler; Elizabeth, Macintyre; Mai, Antonello; Joost H. A., Martens; Saverio, Minucci; H., Ouwehand Willem; Pier Giuseppe, Pelicci; Helene, Pendeville; Porse, Bo; Vardhman, Rakyan; Reik, Wolf; Schrappe, Martin; Dirk, Schubeler; Seifert, Martin; Siebert, Reiner; David, Simmons; Nicole, Soranzo; Salvatore, Spicuglia; Michael, Stratton; Hendrik G., Stunnenberg; Amos, Tanay; David, Torrents; Alfonso, Valencia; Vellenga, Edo; Jorn Walter Martin, Vingron; Spike, Willcocks - 01a Articolo in rivista
paper: NATURE BIOTECHNOLOGY (New York, NY : Nature Pub. Co., [1996-) pp. 224-226 - issn: 1087-0156 - wos: WOS:000301303800012 (232) - scopus: 2-s2.0-84857980747 (260)
11573/513462 - 2012 -
The emerging role of histone lysine demethylases in prostate cancer Francesco, Crea; Lei, Sun; Mai, Antonello; Y. T., Chiang; William L., Farrar; Romano, Danesi; Cheryl D., Helgason - 01a Articolo in rivista
paper: MOLECULAR CANCER (London: BioMed Central-Springer) pp. 52-52 - issn: 1476-4598 - wos: WOS:000308750200001 (66) - scopus: 2-s2.0-84864510460 (76)
11573/884285 - 2012 -
Screening assays for epigenetic targets using native histones as substrates Hauser, Alexander Thomas; Bissinger, Elisabeth Maria; Metzger, Eric; Repenning, Antje; Bauer, Uta Maria; Mai, Antonello; Schüle, Roland; Jung, Manfred - 01a Articolo in rivista
paper: JOURNAL OF BIOMOLECULAR SCREENING (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 18-26 - issn: 1087-0571 - wos: WOS:000298886900003 (16) - scopus: 2-s2.0-84857326796 (18)
11573/485036 - 2012 -
Amino acid starvation induces reactivation of silenced transgenes and latent HIV-1 provirus via down-regulation of histone deacetylase 4 (HDAC4) I., Palmisano; G., Della Chiara; R. L., D'ambrosio; C., Huichalaf; P., Brambilla; S., Corbetta; M., Riba; R., Piccirillo; Valente, Sergio; G., Casari; Mai, Antonello; F., Martinelli Boneschi; D., Gabellini; G., Poli; M. V., Schiaffino - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. E2284-E2293 - issn: 0027-8424 - wos: WOS:000308085200011 (32) - scopus: 2-s2.0-84865194183 (35)
11573/485021 - 2012 -
Highlights of the Keystone Symposium: sirtuins in metabolism, aging and disease Michele M., Maxwell; Julien Francisco Zaldivar, Jolissaint; Mai, Antonello; Tiago F., Outeiro; Aleksey G., Kazanstev - 01a Articolo in rivista
paper: EMBO MOLECULAR MEDICINE (Chichester : Wiley-Blackwell, 2009-) pp. 557-560 - issn: 1757-4676 - wos: WOS:000305943600005 (4) - scopus: 2-s2.0-84863480943 (3)
11573/895421 - 2012 -
6-(Arylmethyl)pyrimidin-4(3H)-ones: Anthology and prospects of highly efficient anti-HIV agents Novakov, I. A.; Artico, M.; Mai, Antonello; Rotili, Dante; Orlinson, B. S.; Brunilina, L. L.; Nawrozkij, M. B. - 01a Articolo in rivista
paper: RUSSIAN CHEMICAL BULLETIN (- New York : SPRINGER
-New York : Consultants Bureau, c1993-) pp. 1399-1418 - issn: 1066-5285 - wos: WOS:000321771700009 (11) - scopus: 2-s2.0-84887395127 (11)
11573/495328 - 2012 -
Carprofen Analogues as Sirtuin Inhibitors: Enzyme and Cellular Studies Paolo, Mellini; Vincenzo, Carafa; Barbara Di, Rienzo; Rotili, Dante; De Vita, Daniela; Roberto, Cirilli; Bruno, Gallinella; Donatella Paola, Provvisiero; Salvatore Di, Maro; Ettore, Novellino; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1905-1908 - issn: 1860-7187 - wos: WOS:000310485200005 (14) - scopus: 2-s2.0-84868149996 (15)
11573/455654 - 2012 -
2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies. Rotili, Dante; A., Samuele; Domenico, Tarantino; Ragno, Rino; Musmuca, Ira; Ballante, Flavio; G., Botta; Morera, Ludovica; Pierini, Marco; R., Cirilli; M. B., Nawrozkij; E., Gonzalez; B., Clotet; Marino, Artico; J. A., Este; G., Maga; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 3558-3562 - issn: 1520-4804 - wos: WOS:000302591100058 (29) - scopus: 2-s2.0-84859804994 (31)
11573/485200 - 2012 -
Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells. Rotili, Dante; Tarantino, D; Carafa, V; Paolini, C; Schemies, J; Jung, M; Botta, G; Di Maro, S; Novellino, E; Steinkühler, C; De Maria, R; Gallinari, P; Altucci, L; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8193-8197 - issn: 0022-2623 - wos: WOS:000309153500023 (32) - scopus: 2-s2.0-84866849116 (35)
11573/759461 - 2012 -
Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells. Rotili, Dante; Tarantino, D; Nebbioso, A; Paolini, C; Huidobro, C; Lara, E; Mellini, P; Lenoci, Alessia; Pezzi, R; Botta, G; Lahtela Kakkonen, M; Poso, A; Steinkühler, C; Gallinari, P; De Maria, R; Fraga, M; Esteller, M; Altucci, L; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 10937-10947 - issn: 0022-2623 - wos: WOS:000312681100009 (81) - scopus: 2-s2.0-84871662210 (84)
11573/477299 - 2012 -
Histone Deacetylase Inhibitors: Structure-Based Modeling and Isoform-Selectivity Prediction Silvestri, Laura; Ballante, Flavio; Mai, Antonello; R., Marshall Garland; Ragno, Rino - 01a Articolo in rivista
paper: JOURNAL OF CHEMICAL INFORMATION AND MODELING (AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036) pp. 2215-2235 - issn: 1549-9596 - wos: WOS:000308254200031 (25) - scopus: 2-s2.0-84865466261 (24)
11573/513460 - 2012 -
Developing novel non-hydroxamate histone deacetylase inhibitors: the chelidamic warhead. Valente, Sergio; Conte, M.; Tardugno, M.; Nebbioso, A; Tinari, G.; Altucci, L.; Mai, Antonello - 01a Articolo in rivista
paper: MEDCHEMCOMM (Cambridge : Royal Society of Chemistry, 2010-) pp. 298-304 - issn: 2040-2503 - wos: WOS:000301966800004 (6) - scopus: 2-s2.0-84857707526 (7)
11573/455694 - 2012 -
Identification of PR-SET7 and EZH2 selective inhibitors inducing cell death in human leukemia U937 cells Valente, Sergio; Ilaria, Lepore; Carmela, Dell'aversa; Maria, Tardugno; Sabrina, Castellano; Gianluca, Sbardella; Stefano, Tomassi; Salvatore Di, Maro; Ettore, Novellino; Di Santo, Roberto; Costi, Roberta; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
paper: BIOCHIMIE (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 2308-2313 - issn: 0300-9084 - wos: WOS:000310929200011 (22) - scopus: 2-s2.0-84867395419 (26)
11573/485203 - 2012 -
p300/CBP-associated factor selectively regulates the extinction of conditioned fear. W., Wei; C. M., Coelho; X., Li; R., Marek; S., Yan; S., Anderson; D., Meyers; C., Mukherjee; G., Sbardella; S., Castellano; C., Milite; Rotili, Dante; Mai, Antonello; P. A., Cole; P., Sah; M. S., Kobor; T. W., Bredy - 01a Articolo in rivista
paper: THE JOURNAL OF NEUROSCIENCE (Baltimore MD: Society of Neuroscience) pp. 11930-11941 - issn: 0270-6474 - wos: WOS:000308213900003 (72) - scopus: 2-s2.0-84865472870 (77)
11573/391029 - 2011 -
Sirtinol Treatment Reduces Inflammation in Human Dermal Microvascular Endothelial Cells Angela, Orecchia; Claudia, Scarponi; Di Felice, Francesca; Cesarini, Elisa; Simona, Avitabile; Mai, Antonello; Mauro, Maria Luisa; Valentina, Sirri; Giovanna, Zambruno; Cristina, Albanesi; Camilloni, Giorgio; Cristina M., Failla - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e24307- - issn: 1932-6203 - wos: WOS:000294803200013 (61) - scopus: 2-s2.0-80052638751 (66)
11573/458436 - 2011 -
EPIGENETIC MODULATION OF PGC-1a ACTIVITY BY GCN5 INHIBITORS: WO2010007085 Carradori, Simone; Secci, Daniela; Mai, Antonello - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare
-London, United Kingdom: Ashley Publications Limited) pp. 1651-1656 - issn: 1354-3776 - wos: WOS:000294966800007 (9) - scopus: 2-s2.0-80053007226 (9)
11573/380081 - 2011 -
Nε-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart Colussi, C; Rosati, J; Straino, S; Spallotta, F; Berni, R; Stilli, D; Rossi, S; Musso, E; Macchi, E; Mai, Antonello; Sbardella, G; Castellano, S; Chimenti, Cristina; Frustaci, Andrea; Nebbioso, A; Altucci, L; Capogrossi, Mc; Gaetano, C. - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (Editore National Academy of Sciences a Washington, DC) pp. 2795-2800 - issn: 1091-6490 - wos: WOS:000287377000035 (88) - scopus: 2-s2.0-79952613152 (89)
11573/414595 - 2011 -
Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: Enzyme selectivity and cellular activity Donghang, Cheng; Valente, Sergio; Sabrina, Castellano; Gianluca, Sbardella; Di Santo, Roberto; Costi, Roberta; Mark T., Bedford; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4928-4932 - issn: 0022-2623 - wos: WOS:000292479600049 (66) - scopus: 2-s2.0-79960191524 (72)
11573/443817 - 2011 -
Application of 3 μm particle-based amylose-derived chiral stationary phases for the enantioseparation of potential histone deacetylase inhibitors. Ferretti, R; Mai, Antonello; Gallinella, B; Zanitti, L; Valente, Sergio; Cirilli, R. - 01a Articolo in rivista
paper: JOURNAL OF CHROMATOGRAPHY A (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 8394-8398 - issn: 0021-9673 - wos: WOS:000297036000012 (19) - scopus: 2-s2.0-80054874258 (19)
11573/442881 - 2011 -
Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors Gianluca, Sbardella; Mai, Antonello; Sara, Bartolini; Sabrina, Castellano; Roberto, Cirilli; Rotili, Dante; Ciro, Milite; Marisabella, Santoriello; Serena, Orlando; Ilaria, Sciamanna; Annalucia, Serafino; Patrizia, Lavia; Corrado, Spadafora - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5927-5936 - issn: 0022-2623 - wos: WOS:000294077300023 (12) - scopus: 2-s2.0-80051873043 (14)
11573/884287 - 2011 -
Specific control of pancreatic endocrine β- and δ-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9 Lenoir, Olivia; Flosseau, Kathleen; Ma, Feng Xia; Blondeau, Bertrand; Mai, Antonello; Bassel Duby, Rhonda; Ravassard, Philippe; Olson, Eric N.; Haumaitre, Cécile; Scharfmann, Raphaël - 01a Articolo in rivista
paper: DIABETES (American Diabetes Association:National Service Center, 1701 North Beaureguard Street:Alexandria, VA 22311:(800)232-3472, (703)549-1500, INTERNET: http://www.diabetes.org/diabetscare, Fax: (703)549-6995) pp. 2861-2871 - issn: 0012-1797 - wos: WOS:000296954600025 (112) - scopus: 2-s2.0-80755168896 (122)
11573/1147220 - 2011 -
Identification of specific and semi-specific SIRT inhibitors through computer-aided studies Mai, Antonello - 01m Editorial/Introduzione in rivista
paper: AGING (Impact Journals LLC) pp. 819-820 - issn: 1945-4589 - wos: WOS:000296798400002 (1) - scopus: 2-s2.0-84864021601 (1)
11573/884294 - 2011 -
Hydroxamic acids: Biological properties and potential uses as therapeutic agents Mai, Antonello - 02a Capitolo o Articolo
book: PATAI - The chemistry of hydroxylamines, oximes and hydroxamic acids - ()
11573/378540 - 2011 -
Gold drug auranofin restricts the viral reservoir in the monkey AIDS model and induces containment of viral load following ART suspension Mark G., Lewis; Sandrina, Dafonseca; N., Chamont; Nicolas, Chomont; Palamara, Anna Teresa; Tardugno, Maria; Mai, Antonello; Matt, Collins; Wendeline L., Wagner; Jake Yalley, Ogunro; Jack, Greenhouse; Barbara, Chirullo; Sandro, Norelli; Enrico, Garaci; Andrea, Savarino - 01a Articolo in rivista
paper: AIDS (- Wolters Kluwer Health, Inc.
-London : Lippincott Williams & Wilkins
-London : Gower Academic Journals, 1987-) pp. 1347-1356 - issn: 0269-9370 - wos: WOS:000292183900001 (73) - scopus: 2-s2.0-79960014190 (78)
11573/442885 - 2011 -
Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3'-C-methyladenosine in leukaemia cells. Meli, M; Tolomeo, M; Grifantini, M; Mai, Antonello; Cappellacci, L; Petrelli, R; Rotili, Dante; Ferro, A; Saiko, P; Szekeres, T; Dusonchet, L. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF ONCOLOGY (National Hellenic Research Foundation:48 Vas Constatinou Avenue, Athens 11635 Greece:011 30 1 7241505, Fax: 011 30 1 7241505Editore attuale:PROFESSOR D A SPANDIDOS, 1, S MERKOURI ST, EDITORIAL OFFICE,, ATHENS, GREECE, 116 35.
Editore precedente:Editorial Academy of the International Journal of Oncology.) pp. - - issn: 1019-6439 - wos: WOS:000289815800026 (9) - scopus: 2-s2.0-79954993415 (9)
11573/379234 - 2011 -
Modulation of the activity of histone acetyltransferases by long chain alkylidenemalonates (LoCAMs) Milite, C; Castellano, S; Benedetti, R; Tosco, A; Ciliberti, C; Vicidomini, C; Boully, L; Franci, G; Altucci, L; Mai, Antonello; Sbardella, G. - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 3690-3701 - issn: 0968-0896 - wos: WOS:000291477600010 (28) - scopus: 2-s2.0-79958265044 (29)
11573/379664 - 2011 -
Biological Effects of MC2050, a Quinazoline-Based PARP-1 Inhibitor, in Human Neuroblastoma and EBV-Positive Burkitt's Lymphoma Cells Mosca, Luciana; Rotili, Dante; Tempera, Italo; Masci, Alessandra; Fontana, Mario; Chiaraluce, Roberta; Mastromarino, Paola; D'erme, Maria; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 606-611 - issn: 1860-7179 - wos: WOS:000288814900006 (12) - scopus: 2-s2.0-79953056639 (11)
11573/418879 - 2011 -
Identification of Small-Molecule Inhibitors of the XendoU Endoribonucleases Family Ragno, Rino; Gioia, Ubaldo; Pietro, Laneve; Bozzoni, Irene; Mai, Antonello; Elisa, Caffarelli - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1797-1805 - issn: 1860-7179 - wos: WOS:000296417000007 (8) - scopus: 2-s2.0-80053427016 (9)
11573/442676 - 2011 -
Photoactivable peptides for identifying enzyme-substrate and protein-protein interactions. Rotili, Dante; Altun, M; Hamed, Rb; Loenarz, C; Thalhammer, A; Hopkinson, Rj; Tian, Ym; Ratcliffe, Pj; Mai, Antonello; Kessler, Bm; Schofield, C. J. - 01a Articolo in rivista
paper: CHEMICAL COMMUNICATIONS (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 1488-1490 - issn: 1359-7345 - wos: WOS:000286389500026 (5) - scopus: 2-s2.0-78751521073 (5)
11573/442886 - 2011 -
Targeting histone demethylases: A new avenue for the fight against cancer Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
paper: GENES & CANCER (Thousand Oaks, CA: SAGE Publications) pp. 663-679 - issn: 1947-6019 - wos: (0) - scopus: 2-s2.0-80054787805 (177)
11573/442882 - 2011 -
A Photoreactive Small-Molecule Probe for 2-Oxoglutarate Oxygenases Rotili, Dante; Mikael, Altun; Akane, Kawamura; Alexander, Wolf; Roman, Fischer; I. K., Leung; Mukram M, Mackeen; Ya Min, Tian; Peter J, Ratcliffe; Mai, Antonello; Benedikt M, Kessler; Christopher J, Schofield - 01a Articolo in rivista
paper: CHEMISTRY & BIOLOGY (Current Science:400 Market Street, Suite 700:Philadelphia, PA 19106:(800)427-1796, (215)574-2266, EMAIL: info@phl.cursci.com, INTERNET: http://www-current-science-group.com, Fax: (215)574-2225) pp. 642-654 - issn: 1074-5521 - wos: WOS:000291499600013 (43) - scopus: 2-s2.0-79957487715 (45)
11573/379781 - 2011 -
Diarylpyrimidine-Dihydrobenzyloxopyrimidine Hybrids: New, Wide-Spectrum Anti-HIV-1 Agents Active at (Sub)-Nanomolar Level. Rotili, Dante; Tarantino, D; Artico, M; Nawrozkij, Mb; Gonzalez Ortega, E; Clotet, B; Samuele, A; Este, Ja; Maga, G; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3091-3096 - issn: 0022-2623 - wos: WOS:000289697800043 (48) - scopus: 2-s2.0-79955455754 (53)
11573/442679 - 2011 -
Simplification of the tetracyclic SIRT1-selective inhibitor MC2141: Coumarin- and pyrimidine-based SIRT1/2 inhibitors with different selectivity profile Rotili, Dante; Vincenzo, Carafa; Domenico, Tarantino; Giorgia, Botta; Angela, Nebbioso; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 3659-3668 - issn: 0968-0896 - wos: WOS:000291477600007 (28) - scopus: 2-s2.0-79958261783 (31)
11573/379790 - 2011 -
PHARMACOLOGICAL INHIBITION OF HDAC6 ATTENUATES ENDOTHELIAL BARRIER DYSFUNCTION INDUCED BY THROMBIN Saito, S; Lasky, Ja; Guo, W; Nguyen, H; Mai, Antonello; Danchuk, S; Sullivan, De; Shan, B. - 01a Articolo in rivista
paper: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 630-634 - issn: 0006-291X - wos: WOS:000291293200022 (24) - scopus: 2-s2.0-79956216267 (25)
11573/884288 - 2011 -
HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer Stronach, Euan A; Alfraidi, Albandri; Rama, Nona; Datler, Christoph; Studd, James B.; Agarwal, Roshan; Guney, Tankut G.; Gourley, Charlie; Hennessy, Bryan T.; Mills, Gordon B.; Mai, Antonello; Brown, Robert; Dina, Roberto; Gabra, Hani - 01a Articolo in rivista
paper: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 4412-4422 - issn: 0008-5472 - wos: WOS:000292287300012 (147) - scopus: 2-s2.0-79959895071 (149)
11573/525044 - 2011 -
Histone deacetylase inhibitors (epigenetic alterations)Targeted Therapies for Hepatocellular Carcinoma Valente, Sergio; Mai, Antonello - 02a Capitolo o Articolo
book: Targeted Therapies for Hepatocellular Carcinoma - (9781780840628)
11573/436635 - 2011 -
Novel Reversible Monoamine Oxidase A Inhibitors: Highly Potent and Selective 3-(1H-Pyrrol-3-yl)-2-oxazolidinones Valente, Sergio; S., Tomassi; Tempera, Giampiero; Saccoccio, Stefania; Agostinelli, Enzo; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8228-8232 - issn: 0022-2623 - wos: WOS:000297445400024 (37) - scopus: 2-s2.0-82555187393 (37)
11573/356064 - 2011 -
Novel Cinnamyl Hydroxyamides and 2-Aminoanilides as Histone Deacetylase Inhibitors: Apoptotic Induction and Cytodifferentiation Activity Valente, Sergio; Tardugno, Maria; Mariarosaria, Conte; Roberto, Cirilli; Andrea, Perrone; Ragno, Rino; Simeoni, Silvia; Tramontano, Anna; Massa, Silvio; Angela, Nebbioso; Marco, Miceli; Gianluigi, Franci; Gerald, Brosch; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 698-712 - issn: 1860-7179 - wos: WOS:000288814900016 (17) - scopus: 2-s2.0-79953046146 (18)
11573/379616 - 2011 -
Discovery, Synthesis, and Pharmacological Evaluation of Spiropiperidine Hydroxamic Acid Based Derivatives as Structurally Novel Histone Deacetylase (HDAC) Inhibitors. Varasi, M; Thaler, F; Abate, A; Bigogno, C; Boggio, R; Carenzi, G; Cataudella, T; Dal Zuffo, R; Fulco, Mc; Rozio, Mg; Mai, Antonello; Dondio, G; Minucci, S; Mercurio, C. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3051-3064 - issn: 0022-2623 - wos: WOS:000289697800038 (48) - scopus: 2-s2.0-79955451248 (54)
11573/434969 - 2010 -
HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation A., Nebbioso; C., Dell'aversana; A., Bugge; R., Sarno; Valente, Sergio; Rotili, Dante; F., Manzo; D., Teti; S., Mandrup; P., Ciana; A., Maggi; Mai, Antonello; H., Gronemeyer; L., Altucci - 01a Articolo in rivista
paper: JOURNAL OF MOLECULAR ENDOCRINOLOGY (Pubblicata da:
SOC ENDOCRINOLOGY, 22 APEX COURT, WOODLANDS, BRADLEY STOKE, BRISTOL, ENGLAND, BS32 4JT
primo editore:
Journal of Endocrinology Limited:17 18 Courtyard Woodlands, Bristol BS12 4NQ United Kingdom:011 44 117 9616046, EMAIL: sxa15@psu.edu, INTERNET: http://www.psu.edu, Fax: 011 44 117 9616071) pp. 219-228 - issn: 0952-5041 - wos: WOS:000282528800005 (52) - scopus: 2-s2.0-77957824326 (56)
11573/365281 - 2010 -
Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases LSD1 and LSD2 Claudia, Binda; Valente, Sergio; Mauro, Romanenghi; Simona, Pilotto; Roberto, Cirilli; Aristotele, Karytinos; Giuseppe, Ciossani; Oronza A., Botrugno; Federico, Forneris; Maria, Tardugno; Dale E., Edmondson; Saverio, Minucci; Andrea, Mattevi; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ([Washington, USA: American Chemical Society] 1879-) pp. 6827-6833 - issn: 0002-7863 - wos: WOS:000277721500044 (236) - scopus: 2-s2.0-77952355653 (256)
11573/13665 - 2010 -
Histone deacetylase inhibitors: Keeping momentum for neuromuscular and cardiovascular diseases treatment Claudia, Colussi; Barbara, Illi; Jessica, Rosati; Spallotta, Francesco; Antonella, Farsetti; Annalisa, Grasselli; Mai, Antonello; Capogrossi Mc, Gaetano C. - 01g Articolo di rassegna (Review)
paper: PHARMACOLOGICAL RESEARCH (Attuale:ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 24-28 OVAL RD, LONDON, ENGLAND, NW1 7DX
Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 3-10 - issn: 1043-6618 - wos: WOS:000278613800002 (39) - scopus: 2-s2.0-77952880971 (41)
11573/13728 - 2010 -
Proteomic profile of differentially expressed plasma proteins from dystrophic mice and following suberoylanilide hydroxamic acid treatment Colussi, C.; Banfi, C.; Brioschi, M.; Tremoli, E.; Straino, S.; Spallotta, F.; Mai, Antonello; Rotili, Dante; Capogrossi Mc, Gaetano C. - 01a Articolo in rivista
paper: PROTEOMICS. CLINICAL APPLICATIONS (Weinheim : Wiley-VCH-Verl.) pp. 71-83 - issn: 1862-8346 - wos: WOS:000274264900007 (30) - scopus: 2-s2.0-77951727320 (31)
11573/13666 - 2010 -
The histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces cardiac arrhythmias in dystrophic mice Colussi, C.; Berni, R.; Rosati, J.; Straino, S.; Vitale, S.; Spallotta, F.; Baruffi, S.; Bocchi, L.; Delucchi, F.; Rossi, S.; Savi, M.; Rotili, Dante; Quaini, F.; Macchi, E.; Stilli, D.; Musso, E.; Mai, Antonello; Capogrossi Mc, Gaetano C. - 01a Articolo in rivista
paper: CARDIOVASCULAR RESEARCH (editore attuale:
ELSEVIER SCIENCE BV, PO BOX 211, AMSTERDAM, NETHERLANDS, 1000 AE
primo editore:
BMJ / British Medical Journal Publishing Group:PO Box 299, London WC1H 9TD United Kingdom:011 44 20 73836270, EMAIL: subscriptions@bmjgroup.com, INTERNET: http://www.bmjpg.com/bmj, Fax: 011 44 20 73836402) pp. 73-82 - issn: 0008-6363 - wos: WOS:000278690000012 (40) - scopus: 2-s2.0-77955165005 (42)
11573/434968 - 2010 -
TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration Daniela, Palacios; Mozzetta, Chiara; Silvia, Consalvi; Giuseppina, Caretti; Valentina, Saccone; Valentina, Proserpio; Victor E., Marquez; Valente, Sergio; Mai, Antonello; Sonia V., Forcales; Vittorio, Sartorelli; Pier Lorenzo, Puri - 01a Articolo in rivista
paper: CELL STEM CELL (Cambridge: Cell Press (an imprint of Elsevier)) pp. 455-469 - issn: 1934-5909 - wos: WOS:000283270600008 (318) - scopus: 2-s2.0-77957357566 (341)
11573/12800 - 2010 -
Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation E., Borbone; M. T., Berlingieri; F., De Bellis; A., Nebbioso; G., Chiappetta; Mai, Antonello; L., Altucci; A., Fusco - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 105-116 - issn: 0950-9232 - wos: WOS:000273373500010 (66) - scopus: 2-s2.0-73849114072 (69)
11573/13428 - 2010 -
Synthesis and Biological Evaluation of N-Hydroxyphenylacrylamides and
N-Hydroxypyridin-2-ylacrylamides as Novel Histone Deacetylase Inhibitors Florian, Thaler; Andrea, Colombo; Mai, Antonello; Raffaella, Amici; Chiara, Bigogno; Roberto, Boggio; Anna, Cappa; Simone, Carrara; Tiziana, Cataudella; Fulvia, Fusar; Eleonora, Gianti; Samuele Joppolo Di, Ventimiglia; Maurizio, Moroni; Davide, Munari; Gilles, Pain; Nickolas, Regalia; Luca, Sartori; Stefania, Vultaggio; Giulio, Dondio; Stefania, Gagliardi; Saverio, Minucci; Ciro, Mercurio; Mario, Varasi - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 822-839 - issn: 0022-2623 - wos: WOS:000273672100028 (29) - scopus: 2-s2.0-77249133651 (30)
11573/13724 - 2010 -
Synthesis and Biological Characterization of Amidopropenyl Hydroxamates as HDAC Inhibitors Florian, Thaler; Mario, Varasi; Andrea, Colombo; Roberto, Boggio; Davide, Munari; Nickolas, Regalia; Marco G, Rozio; Veronica, Reali; Anna E, Resconi; Mai, Antonello; Stefania, Gagliardi; Giulio, Dondio; Saverio, Minucci; Ciro, Mercurio - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1359-1372 - issn: 1860-7179 - wos: WOS:000281061300021 (13) - scopus: 2-s2.0-77955098441 (14)
11573/12804 - 2010 -
Histone deacetylase-3 Activation Promotes TNF-α Expression in Cardiomyocytes During
Lipopolysaccharide Stimulation Huaqing, Zhu; Limei, Shan; Peter W., Schiller; Mai, Antonello; Tianqing, Peng - 01a Articolo in rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 9429-9436 - issn: 0021-9258 - wos: WOS:000276165900015 (82) - scopus: 2-s2.0-77951226550 (91)
11573/121815 - 2010 -
Combining 3-D QSAR with Ligand Based and Structure Based Alignment Procedures for in Silico Screening of New Hepatitis C Virus NS5B Polymerase Inhibitors I., Musmuca; A., Caroli; Mai, Antonello; N., Kaushik Basu; P., Arora; Ragno, Rino - 01a Articolo in rivista
paper: JOURNAL OF CHEMICAL INFORMATION AND MODELING (AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036) pp. 662-676 - issn: 1549-9596 - wos: WOS:000276915200020 (48) - scopus: 2-s2.0-77951993951 (58)
11573/12801 - 2010 -
Lysine Acetylation Regulates Bruton’s Tyrosine Kinase in B
Cell Activation Liu, Z; Mai, Antonello; Sun, J. - 01a Articolo in rivista
paper: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 244-254 - issn: 0022-1767 - wos: WOS:000272985300029 (12) - scopus: 2-s2.0-73949137382 (12)
11573/884290 - 2010 -
Small-molecule chromatin-modifying agents: Therapeutic applications Mai, Antonello - 01a Articolo in rivista
paper: EPIGENOMICS (London: Future Medicine, 2009-) pp. 307-324 - issn: 1750-1911 - wos: WOS:000278299100014 (25) - scopus: 2-s2.0-77954139965 (30)
11573/442677 - 2010 -
Characterization of Sirtuin Inhibitors in Nematodes Expressing a Muscular Dystrophy Protein Reveals Muscle Cell and Behavioral Protection by Specific Sirtinol Analogues Matthieu Y., Pasco; Rotili, Dante; Lucia, Altucci; Francesca, Farina; Guy A., Rouleau; Mai, Antonello; Christian, Neri - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1407-1411 - issn: 0022-2623 - wos: WOS:000274270900047 (37) - scopus: 2-s2.0-77249153712 (40)
11573/456124 - 2010 -
The specific character of the reaction of derivatives of 2-thioxo-2,3-dihydropyrimidin-4(1H)-one with iodomethane and alkyl chloromethyl sulfides. Novakov, Ia; Orlinson, B; Nawrozkij, Mb; Mai, Antonello; Artico, Marino; Rotili, Dante; Eremiychuk, As; Gordeeva, Ea; Brunilina, Ll; Este, J. A. - 01a Articolo in rivista
paper: CHEMISTRY OF HETEROCYCLIC COMPOUNDS (Consultants Bureau:A Division of Plenum Publishing Corporation, 233 Spring Street, Sixth Floor:New York, NY 10013:(800)221-9369, (212)620-8082, Fax: (212)463-0742) pp. - - issn: 0009-3122 - wos: WOS:000279454900010 (1) - scopus: 2-s2.0-77954638922 (0)
11573/895420 - 2010 -
Evaluation of histone deacetylases as drug targets in Huntington's disease models Quinti, Luisa; Chopra, Vanita; Rotili, Dante; Valente, Sergio; Amore, Allison; Franci, Gianluigi; Meade, Sarah; Valenza, Marta; Altucci, Lucia; Maxwell, Michele M.; Cattaneo, Elena; Hersch, Steven; Mai, Antonello; Kazantsev, Aleksey - 02a Capitolo o Articolo
book: PLOS CURRENTS - ()
11573/229854 - 2010 -
Chemogenomic profiling of the cellular effects associated with histone H3 acetylation impairment by a quinoline-derived compound Roberta, Ruotolo; Federica, Tosi; Stefano, Vernarecci; Ballario, Paola; Mai, Antonello; Patrizia, Filetici; Simone, Ottonello - 01a Articolo in rivista
paper: GENOMICS (Amsterdam The Netherlands; Boston: Elsevier
:Orlando, FL: Academic Press Incorporated) pp. 272-280 - issn: 0888-7543 - wos: WOS:000283894300003 (11) - scopus: 2-s2.0-78649448009 (10)
11573/456116 - 2010 -
Identification of Tri- and Tetracyclic Pyrimidinediones as Sirtuin Inhibitors Rotili, Dante; Tarantino, Domenico; Vincenzo, Carafa; Ester, Lara; Sarah, Meade; Giorgia, Botta; Angela, Nebbioso; Jorg, Schemies; Manfred, Jung; Aleksey G, Kazantsev; Manel, Esteller; Mario F, Fraga; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 674-677 - issn: 1860-7179 - wos: WOS:000277725100005 (47) - scopus: 2-s2.0-77951697156 (46)
11573/230646 - 2010 -
Design, Synthesis and Biological Evaluation of Carboxy
Analogues of Arginine Methyltransferase Inhibitor 1
(AMI-1) Sabrina, Castellano; Ciro, Milite; Ragno, Rino; Silvia, Simeoni; Mai, Antonello; Vittorio, Limongelli; Ettore, Novellino; Ingo, Bauer; Gerald, Brosch; Astrid, Spannhoff; Donghang, Cheng; Mark T., Bedford; Gianluca, Sbardella - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 398-414 - issn: 1860-7179 - wos: WOS:000275521200009 (57) - scopus: 2-s2.0-77249086700 (62)
11573/193713 - 2010 -
HDACi di classe II inibiscono la resistenza indotta in vitro al fluconazolo in Cryptococcus spp Simonetti, Giovanna; D'auria, Felicia Diodata; Panella, Simona; S., Di Meo; Passariello, Claudio; Mai, Antonello; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
book: 8° Congresso della Società Italiana di Microbiologia Farmaceutica - ()
11573/229552 - 2010 -
Nitric oxide determines mesodermic differentiation of mouse embryonic stem cells by activating class IIa histone deacetylases: potential therapeutic implications in a mouse model of hindlimb ischemia Spallotta, F; Rosati, J; Straino, S; Nanni, S; Grasselli, A; Ambrosino, V; Rotili, Dante; Valente, Sergio; Farsetti, A; Mai, Antonello; Capogrossi, Mc; Gaetano, C; Illi, B. - 01a Articolo in rivista
paper: STEM CELLS (Alphamed Press Incorporated:1 Prestige Place, Suite 290:Miamisburg, OH 45342:(937)291-2355, EMAIL: alphamedpress@alphamedpress.com, INTERNET: http://www.alphamedpress.com, Fax: (937)291-4229) pp. 431-442 - issn: 1066-5099 - wos: WOS:000277093700006 (50) - scopus: 2-s2.0-77950581254 (50)
11573/229551 - 2009 -
Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence Andrea, Savarino; Mai, Antonello; Sandro, Norelli; Sary El, Daker; Valente, Sergio; Rotili, Dante; Lucia, Altucci; Palamara, Anna Teresa; Enrico, Garaci - 01a Articolo in rivista
paper: RETROVIROLOGY (London : BioMed Central) pp. 52-52 - issn: 1742-4690 - wos: WOS:000267430700001 (96) - scopus: 2-s2.0-67649259174 (97)
11573/13145 - 2009 -
Chiral HPLC separation and absolute configuration of novel S-DABO derivatives. Cirilli, R; Ferretti, R; La Torre, F; Borioni, A; Fares, V; Camalli, M; Faggi, C; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
paper: CHIRALITY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 604-612 - issn: 0899-0042 - wos: WOS:000267250300007 (10) - scopus: 2-s2.0-67649403720 (11)
11573/360441 - 2009 -
Modulatori epigenetici: potenziali target per strategie terapeutiche innovative Di Vincenzo, N; Simonetti, Giovanna; Passariello, Claudio; Nencioni, Lucia; Panella, Simona; Mai, Antonello; Garaci, E; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
book: Giornate del Dipartimento di Scienze di Sanità Pubblica "G. Sanarelli" - ()
11573/12747 - 2009 -
Histone acetyltransferase inhibitors and preclinical studies Fabio, Manzo; Francesco Paolo, Tambaro; Mai, Antonello; A., Altucci - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare
-London, United Kingdom: Ashley Publications Limited) pp. 761-774 - issn: 1354-3776 - wos: WOS:000267103900003 (89) - scopus: 2-s2.0-67649379393 (93)
11573/456128 - 2009 -
Reactions of 6-benzyl-5-methyl-2-(methylsulfanyl)pyrimidin-4(3H)-one with aliphatic and aliphatic-aromatic amines I. A., Novakov; B. S., Orlinson; Mai, Antonello; Artico, Marino; Rotili, Dante; M. B., Navrotskii; E. A., Gordeeva; E. N., Savel'ev - 01a Articolo in rivista
paper: RUSSIAN JOURNAL OF ORGANIC CHEMISTRY (pubblicata da:
MAIK NAUKA/INTERPERIODICA, C/O KLUWER ACADEMIC-PLENUM PUBLISHERS, 233 SPRING ST, NEW YORK, USA, NY, 10013-1578) pp. 773-776 - issn: 1070-4280 - wos: WOS:000266829300021 (5) - scopus: 2-s2.0-67049164618 (3)
11573/360909 - 2009 -
Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect. Lara, E; Mai, Antonello; Calvanese, V; Altucci, L; Lopez Nieva, P; Martinez Chantar, Ml; Varela Rey, M; Rotili, Dante; Nebbioso, A; Ropero, S; Montoya, G; Oyarzabal, J; Velasco, S; Serrano, M; Witt, M; Villar Garea, A; Inhof, A; Mato, Jm; Esteller, M; Fraga, Mf - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 781-791 - issn: 0950-9232 - wos: WOS:000263320000001 (219) - scopus: 2-s2.0-60149091562 (239)
11573/456126 - 2009 -
Stereoselective synthesis of 2-substituted 6-[1-(2,6-difluorophenyl)ethyl]-5-methylpyrimidin-4(3H)-ones. Mai, Antonello; Artico, Marino; Rotili, Dante; Novakov, Ia; Orlinson, Bs; Navrotskii, Mb; Eremiichuk, As; Gordeeva, E. A. - 01a Articolo in rivista
paper: RUSSIAN JOURNAL OF ORGANIC CHEMISTRY (pubblicata da:
MAIK NAUKA/INTERPERIODICA, C/O KLUWER ACADEMIC-PLENUM PUBLISHERS, 233 SPRING ST, NEW YORK, USA, NY, 10013-1578) pp. 1531-1534 - issn: 1070-4280 - wos: WOS:000271810500019 (1) - scopus: 2-s2.0-70450201365 (0)
11573/13146 - 2009 -
Epi-drugs to fight cancer: From chemistry to cancer treatment, the road ahead Mai, Antonello; Lucia, Altucci - 01a Articolo in rivista
paper: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 199-213 - issn: 1357-2725 - wos: WOS:000262620400025 (165) - scopus: 2-s2.0-56149090684 (180)
11573/361722 - 2009 -
Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases Mai, Antonello; Rotili, Dante; Tarantino, Domenico; Angela, Nebbioso; Sabrina, Castellano; Gianluca, Sbardella; Marc, Tini; Lucia, Altucci - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 1132-1135 - issn: 0960-894X - wos: WOS:000263295200021 (67) - scopus: 2-s2.0-59749103028 (72)
11573/442678 - 2009 -
Histone deacetylase inhibitors and neurodegenerative disorders: Holding the promise Mai, Antonello; Rotili, Dante; Valente, Sergio; Aleksey, Kazantsev - 01a Articolo in rivista
paper: CURRENT PHARMACEUTICAL DESIGN (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 3940-3957 - issn: 1381-6128 - wos: WOS:000271385600003 (69) - scopus: 2-s2.0-70649108817 (70)
11573/229211 - 2009 -
New pyrrole-based histone deacetylase inhibitors: Binding mode, enzyme- and cell-based investigations Mai, Antonello; Valente, Sergio; Angela, Nebbioso; Simeoni, Silvia; Ragno, Rino; Silvio, Massa; Gerald, Brosch; Floriana De, Bellis; Fabio, Manzo; Lucia, Altucci - 01a Articolo in rivista
paper: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 235-247 - issn: 1357-2725 - wos: WOS:000262620400028 (25) - scopus: 2-s2.0-55949088703 (27)
11573/12799 - 2009 -
Study of 1,4-Dihydropyridine Structural Scaffold: Discovery of Novel Sirtuin Activators and Inhibitors Mai, Antonello; Valente, Sergio; Sarah, Meade; Vincenzo, Carafa; Maria, Tardugno; Angela, Nebbioso; Andrea, Galmozzi; Nico, Mitro; Emma De, Fabiani; Lucia, Altucci; Aleksey, Kazantsev - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5496-5504 - issn: 0022-2623 - wos: WOS:000269655500022 (151) - scopus: 2-s2.0-69949096844 (157)
11573/12746 - 2009 -
Pyrrole-Based Hydroxamates and 2-Aminoanilides: Histone Deacetylase Inhibition and Cellular Activities Mariarosaria, Conte; Maria, Tardugno; Silvio, Massa; Angela, Nebbioso; Lucia, Altucci; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1411-1415 - issn: 1860-7179 - wos: WOS:000270027800002 (10) - scopus: 2-s2.0-69749113873 (10)
11573/13427 - 2009 -
Histone post-translational modifications by HPLC-ESI-MS after HT29 cell treatment with HDAC inhibitors Marina, Naldi; Natalia, Calonghi; Lanfranco, Masotti; Carola, Parolin; Valente, Sergio; Mai, Antonello; Vincenza, Andrisano - 01a Articolo in rivista
paper: PROTEOMICS (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 5437-5445 - issn: 1615-9853 - wos: WOS:000273515000006 (23) - scopus: 2-s2.0-73149088831 (26)
11573/434973 - 2009 -
Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes. Nebbioso, A; Manzo, F; Miceli, M; Conte, M; Manente, L; Baldi, A; De Luca, A; Rotili, Dante; Valente, Sergio; Mai, Antonello; Usiello, A; Gronemeyer, H; Altucci, L. - 01a Articolo in rivista
paper: EMBO REPORTS (Oxford : Oxford University Press, 2000-) pp. 776-782 - issn: 1469-221X - wos: WOS:000267599700022 (119) - scopus: 2-s2.0-67650083046 (120)
11573/227010 - 2009 -
Non-cancer uses of histone deacetylase inhibitors: effects on infectious diseases and β-hemoglobinopathies Rotili, Dante; Simonetti, Giovanna; A., Savarino; Palamara, Anna Teresa; Migliaccio, A. R.; Mai, Antonello - 01a Articolo in rivista
paper: CURRENT TOPICS IN MEDICINAL CHEMISTRY (Hilversum : Bentham Science Publishers) pp. 272-291 - issn: 1568-0266 - wos: WOS:000265798300006 (39) - scopus: 2-s2.0-65449142086 (47)
11573/358514 - 2009 -
Inibitori delle Istone Deacetilasi di Classe II riducono la replicazione del virus influenzale in vitro Simonetti, Giovanna; Panella, Simona; Nencioni, Lucia; Mai, Antonello; Garaci, E; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
book: 37° CONGRESSO NAZIONALE DELLA SOCIETA' ITALIANA DI MICROBIOLOGIA - ()
11573/361898 - 2008 -
Histone deacetylase inhibitors and hemoglobin F induction in beta-thalassemia A. R., Migliaccio; Rotili, Dante; A., Nebbioso; G., Atweh; Mai, Antonello - 01a Articolo in rivista
paper: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 2341-2347 - issn: 1357-2725 - wos: WOS:000259134100002 (13) - scopus: 2-s2.0-48349094044 (17)
11573/13144 - 2008 -
HDAC-class II specific inhibition involves HDAC proteasome-dependent degradation mediated by RANBP2 Annamaria, Scognamiglio; Angela, Nebbioso; Fabio, Manzo; Valente, Sergio; Mai, Antonello; Lucia, Altucci - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 2030-2038 - issn: 0167-4889 - wos: WOS:000259917200036 (47) - scopus: 2-s2.0-50849143144 (49)
11573/13367 - 2008 -
HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment C., Colussi; Mozzetta, Chiara; A., Gurtner; B., Illi; J., Rosati; S., Straino; G., Ragone; M., Pescatori; G., Zaccagnini; A., Antonini; G., Minetti; F., Martelli; G., Piaggio; P., Gallinari; C., Steinkulher; E., Clementi; C., Dell'aversana; L., Altucci; Mai, Antonello; M. C., Capogrossi; Gaetano C., Puri Pl - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 19183-19187 - issn: 0027-8424 - wos: WOS:000261706600031 (223) - scopus: 2-s2.0-58049221125 (233)
11573/359674 - 2008 -
SIRTUINS, THE NAD-DEPENDENT HISTONE DEACETYLASES, AS NEW THERAPEUTIC TARGETS IN TUMOR ANGIOGENESIS Chiani, Francesco; Orecchia, A; Cesarini, Elisa; Avitabile, S; Scarponi, C; Albanesi, C; Mai, Antonello; Zambruno, G; Camilloni, Giorgio; Failla, C. - 04a Atto di comunicazione a congresso
book: 50th Annual Meeting of Italian Cancer Society - ()
11573/363940 - 2008 -
Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases Gianluca, Sbardella; Sabrina, Castellano; Caterina, Vicidomini; Rotili, Dante; Angela, Nebbioso; Marco, Miceli; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 2788-2792 - issn: 0960-894X - wos: WOS:000255444300005 (82) - scopus: 2-s2.0-42949089945 (88)
11573/358405 - 2008 -
Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling Illi, B.; Dello Russo, Claudio; Colussi, C.; Rosati, J.; Pallaoro, M.; Spallotta, F.; Rotili, Dante; Valente, Sergio; Ragone, G.; Martelli, F.; Biglioli, P.; Steinkuhler, C.; Gallinari, P.; Mai, Antonello; Capogrossi, M. C.; Gaetano, C. - 01a Articolo in rivista
paper: CIRCULATION RESEARCH (Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320
PRimo editore:
Baltimore, Md. : Grune & Stratton, c1953-) pp. 51-58 - issn: 0009-7330 - wos: WOS:000252217400009 (97) - scopus: 2-s2.0-37849010584 (102)
11573/13425 - 2008 -
Epigenetric Multiple Ligands: Mixed Histone/Protein Methyltransferase, Acetyltransferase, and Class III Deacetylase (Sirtuin) Inhibitors Mai, A.; Cheng, D; Bedford, M. T.; Valente, S; Nebbioso, A; Perrone, A; Brosch, G; Sbardella, G; De Bellis, F; Miceli, M; Altucci, L - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2279-2290 - issn: 0022-2623 - wos: WOS:000254709100033 (122) - scopus: 2-s2.0-41849146748 (128)
11573/363936 - 2008 -
Novel uracil-based 2-aminoanilide and 2-aminoanilide-like derivatives: Histone deacetylase inhibition and in-cell activities Mai, Antonello; Andrea, Perrone; Angela, Nebbioso; Rotili, Dante; Valente, Sergio; Maria, Tardugno; Silvio, Massa; Floriana De, Bellis; Lucia, Altucci - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 2530-2535 - issn: 0960-894X - wos: WOS:000255246400002 (25) - scopus: 2-s2.0-41849089386 (28)
11573/363647 - 2008 -
5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile. Nawrozkij, Mb; Rotili, Dante; Tarantino, Domenico; Botta, G; Eremiychuk, As; Musmuca, Ira; Ragno, Rino; Samuele, A; Zanoli, S; Armand Ugón, M; Clotet Codina, I; Novakov, Ia; Orlinson, Bs; Maga, G; Esté, Ja; Artico, Marino; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4641-4652 - issn: 0022-2623 - wos: WOS:000258289800033 (54) - scopus: 2-s2.0-49449113636 (57)
11573/365241 - 2008 -
Class II-selective histone deacetylase inhibitors. Part 2: Alignment-independent GRIND 3-D QSAR, homology and docking studies Ragno, Rino; Silvia, Simeoni; Rotili, Dante; Antonella, Caroli; Giorgia, Botta; Gerald, Brosch; Silvio, Massa; Mai, Antonello - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 621-632 - issn: 0223-5234 - wos: WOS:000254777400019 (38) - scopus: 2-s2.0-40049110686 (46)
11573/362098 - 2008 -
Substrate-induced stable enzyme-inhibitor complex formation allows tight binding of novel 2-aminopyrimidin-4(3H)-ones to drug-resistant HIV-1 reverse transcriptase mutants. Samuele, A; Facchini, M; Rotili, Dante; Mai, Antonello; Artico, Marino; Armand Ugón, M; Esté, Ja; Maga, G. - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1412-1418 - issn: 1860-7179 - wos: WOS:000259628300014 (9) - scopus: 2-s2.0-54849438319 (9)
11573/226594 - 2008 -
Modulatori epigenetici: una via alternativa nella terapia delle infezioni fungine sistemiche Simonetti, Giovanna; Palamara, Anna Teresa; Passariello, Claudio; Di Vincenzo, N; Mai, Antonello; Garaci, E. - 04a Atto di comunicazione a congresso
book: Bollettino della SIM - ()
11573/13369 - 2008 -
Specific Activity of Class II Histone Deacetylases in Human Breast Cancer Cells V., Duong; C., Bret; L., Altucci; Mai, Antonello; C., Duraffourd; J., Loubersac; P. O., Harmand; S., Bonnet; Valente, Sergio; T., Maudelonde; V., Cavailles; N., Boulle - 01a Articolo in rivista
paper: MOLECULAR CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 1908-1919 - issn: 1541-7786 - wos: WOS:000261824800011 (84) - scopus: 2-s2.0-57749101152 (92)
11573/519300 - 2007 -
Sirtuins modulate the inflammation response in skin microvascular endothelial cells C. M., Failla; Chiani, Francesco; A., Orecchia; C., Albanesi; Cesarini, Elisa; C., Scarponi; Mai, Antonello; G., Zambruno; Camilloni, Giorgio - 04b Atto di convegno in volume
paper: JOURNAL OF INVESTIGATIVE DERMATOLOGY (Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680) pp. S88-S88 - issn: 0022-202X - wos: WOS:000249933400527 (0) - scopus: (0)
conference: 37th Annual Meeting of the European-Society-for-Dermatological-Research (Zurich; Switzerland)
book: JOURNAL OF INVESTIGATIVE DERMATOLOGY - ()
11573/13081 - 2007 -
The therapeutic uses of chromatin-modifying agents Mai, Antonello - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC TARGETS (--London United Kingdom:Informa Healthcare
-London : Ashley, 2002-.) pp. 835-851 - issn: 1472-8222 - wos: WOS:000247105600011 (50) - scopus: 2-s2.0-34250316675 (56)
11573/363321 - 2007 -
Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains Mai, Antonello; Artico, Marino; Rotili, Dante; Tarantino, Domenico; Clotet Codina, I; Armand Ugón, M; Ragno, Rino; Simeoni, S; Sbardella, G; Nawrozkij, M. B.; Samuele, A; Maga, G; Esté, J. A. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5412-5424 - issn: 0022-2623 - wos: WOS:000250557100019 (58) - scopus: 2-s2.0-35848949355 (62)
11573/362130 - 2007 -
Identification of two new synthetic histone deacetylase inhibitors that modulate globin gene expression in erythroid cells from healthy donors and patients with thalassemia Mai, Antonello; K., Jelicic; Rotili, Dante; A., Di Noia; E., Alfani; Valente, Sergio; L., Altucci; A., Nebbioso; S., Massa; R., Galanello; G., Brosch; A. R., Migliaccio; G., Migliaccio - 01a Articolo in rivista
paper: MOLECULAR PHARMACOLOGY (American Society for Pharmacology and Experimental Therapeutics:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7024, EMAIL: pstoute@aspet.org, INTERNET: http://www.aspet.org, Fax: (301)634-7099) pp. 1111-1123 - issn: 0026-895X - wos: WOS:000250385300004 (29) - scopus: 2-s2.0-35548933854 (30)
11573/365178 - 2007 -
Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans Mai, Antonello; Rotili, Dante; Massa, Silvio; Gerald, Brosch; Simonetti, Giovanna; Passariello, Claudio; Palamara, Anna Teresa - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 1221-1225 - issn: 0960-894X - wos: WOS:000244943300017 (80) - scopus: 2-s2.0-33846938126 (85)
11573/240206 - 2007 -
Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors Mai, Antonello; Valente, Sergio; Donghang, Cheng; Andrea, Perrone; Ragno, Rino; Simeoni, Silvia; Gianluca, Sbardella; Gerald, Brosch; Mark T, Bedford - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 987-991 - issn: 1860-7179 - wos: WOS:000248065600003 (53) - scopus: 2-s2.0-41849112166 (52)
11573/364545 - 2007 -
Novel pyrrole-containing histone deacetylase inhibitors endowed with cytodifferentiation activity Mai, Antonello; Valente, Sergio; Rotili, Dante; Silvio, Massa; Giorgia, Botta; Gerald, Brosch; Marco, Miceli; Angela, Nebbioso; Lucia, Altucci - 01a Articolo in rivista
paper: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 1510-1522 - issn: 1357-2725 - wos: WOS:000248566700025 (14) - scopus: 2-s2.0-34447268739 (14)
11573/51617 - 2007 -
Docking and 3-D QSAR Studies on SIRT2 Inhibitors: A GRID/GOLPE Approach on Different Series of Compounds. Ragno, Rino; Mai, Antonello; Simeoni, Silvia; Caroli, Antonia; Rotili, Dante; Botta, Giorgia - 04a Atto di comunicazione a congresso
conference: Frontiers in CNS and Oncology Medicinal Chemistry, ACS-EFMC (Siena, Italy)
book: Frontiers in CNS and Oncology Medicinal Chemistry, ACS-EFMC - ()
11573/51660 - 2007 -
New Aroyl-Pyrrolyl-Hydroxy-Amides APHAs: Class I and II Histone Deacetylase Inhibiting Activity and Binding Mode Analysis through Molecular Docking Experiments Ragno, Rino; Mai, Antonello; Simeoni, Silvia; Caroli, Antonia; Valente, Sergio; Perrone, Andrea - 04a Atto di comunicazione a congresso
conference: Frontiers in CNS and Oncology Medicinal Chemistry, ACS-EFMC (Siena, Italy)
book: Frontiers in CNS and Oncology Medicinal Chemistry, ACS-EFMC - ()
11573/239247 - 2007 -
Small Molecole Inhibitors of Histone Arginine Methyltransferases: Homology Modeling, Molecular Docking, Binding Mode Analysis, and Biological Evaluation. Ragno, Rino; Silvia, Simeoni; Sabrina, Castellano; Caterina, Vicidomini; Mai, Antonello; Tramontano, Anna; Claudia, Bonaccini; Patrick, Trojer; D., Ingo Bauer; Gerald, Brosch; Gianluca, Sbardella - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1241-1253 - issn: 0022-2623 - wos: WOS:000244895900016 (94) - scopus: 2-s2.0-33947685838 (102)
11573/361993 - 2007 -
Slow-, tight-binding HIV-1 reverse transcriptase non-nucleoside inhibitors highly active against drug-resistant mutants Reynel, Cancio; Mai, Antonello; Rotili, Dante; Marino, Artico; Gianluca, Sbardella; Imma Clotet, Codina; José A, Este; Emmanuele, Crespan; Samantha, Zanoli; Ulrich, Hubscher; Silvio, Spadari; Giovanni, Maga - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 445-448 - issn: 1860-7179 - wos: WOS:000246011500006 (20) - scopus: 2-s2.0-34547939030 (22)
11573/237899 - 2007 -
Regolazione epigenetica in Candida albicans: potenziale target per strategie terapeutiche innovative Simonetti, Giovanna; Passariello, Claudio; N., Di Vincenzo; Mai, Antonello; E., Garaci; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
book: 35° CONGRESSO NAZIONALE SOCIETA' ITALIANA DI MICROBIOLOGIA - ()
11573/362194 - 2007 -
Histone deacetylase inhibitors may reduce pathogenicity and virulence in Candida albicans Simonetti, Giovanna; Passariello, Claudio; Rotili, Dante; Mai, Antonello; Enrico, Garaci; Palamara, Anna Teresa - 01a Articolo in rivista
paper: FEMS YEAST RESEARCH (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1371-1380 - issn: 1567-1356 - wos: WOS:000250298000018 (42) - scopus: 2-s2.0-35448985401 (43)
11573/12852 - 2007 -
Quinoline Derivative MC1626, a Putative GCN5 Histone Acetyltransferase (HAT) Inhibitor, Exhinits HAT-Independent Activity against Toxoplasma gondii Smith, At; Livingston, Mr; Mai, Antonello; Filetici, P; Queener, Sf; Sullivan W. J., Jr - 01a Articolo in rivista
paper: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (American Society for Microbiology:PO Box 11127:Birmingham, AL 35201:(800)633-4931, (205)995-1567, EMAIL: asm.nonmembers.subs@ebsco.com, INTERNET: http://www.asm.org, Fax: (205)995-1588) pp. 1109-1111 - issn: 0066-4804 - wos: WOS:000244665500050 (29) - scopus: 2-s2.0-33847681408 (32)
11573/362375 - 2006 -
Analytical and semipreparative high performance liquid chromatography separation of stereoisomers of novel 3,4-dihydropyrimidin-4(3H)-one derivatives on the immobilised amylose-based Chiralpack IA chiral stationary phase. Cirilli, R; Ferretti, R; Gallinella, B; La Torre, F; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
paper: JOURNAL OF SEPARATION SCIENCE (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 1399-1406 - issn: 1615-9306 - wos: WOS:000239291200011 (27) - scopus: 2-s2.0-33746470231 (29)
11573/12796 - 2006 -
Inhibition of Histone Deacetylase Class I but not Class II is Critical for the Sensitization of Leukemic Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis Inoue, S; Mai, Antonello; Dyer, Js; Cohen, Gm - 01a Articolo in rivista
paper: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 6785-6792 - issn: 0008-5472 - wos: WOS:000238825800044 (121) - scopus: 2-s2.0-33746144518 (129)
11573/358996 - 2006 -
Small-Molecule Inhibitors of Histone Acetyltransferase Activity: Identification and Biological Properties Mai, A; Rotili, D.; Tarantino, D; Ornaghi, P; Tosi, F; Vicidomini, C; Sbardella, G; Nebbioso, A; Miceli, M; Altucci, L; Filetici, P - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6897-6907 - issn: 0022-2623 - wos: WOS:000241894000031 (123) - scopus: 2-s2.0-33750989910 (130)
11573/12854 - 2006 -
Identification of small molecules inhibitors of GCN5 histone acetyltransferase activity Mai, Antonello; Rotili, Dante; Ornaghi, P; Tosi, F; Vicidomini, C; Sbardella, G; Nebbioso, A; Altucci, L; Filetici, P. - 01a Articolo in rivista
paper: ARKIVOC (ARKAT USA INC, C/O ALAN R KATRITZKY, UNIV FLORIDA, DEPT CHEMISTRY, PO BOX 117200, GAINESVILLE, USA, FL, 32611) pp. 24-37 - issn: 1551-7004 - wos: WOS:000242574600004 (6) - scopus: 2-s2.0-33744470562 (7)
11573/363353 - 2006 -
Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors Mai, Antonello; Silvio, Massa; Rotili, Dante; Silvia, Simeoni; Ragno, Rino; Giorgia, Botta; Angela, Nebbioso; Marco, Miceli; Lucia, Altucci; Gerald, Brosch - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6046-6056 - issn: 0022-2623 - wos: WOS:000240826200019 (58) - scopus: 2-s2.0-33749258885 (57)
11573/234238 - 2006 -
Aroyl-pyrrolyl hydroxyamides: Influence of pyrrole C4-phenylacetyl substitution on histone deacetylase inhibition Mai, Antonello; Silvio, Massa; Valente, Sergio; Silvia, Simeoni; Ragno, Rino; Patrizia, Bottoni; Roberto, Scatena; Gerald, Brosch - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 225-237 - issn: 1860-7179 - wos: WOS:000202945600008 (22) - scopus: 2-s2.0-33646483786 (23)
11573/234818 - 2006 -
3-D QSAR Studies on Histone Deacetylase Inhibitors. A GOLPE/GRID Approach on Different Series of Compounds. Ragno, Rino; Simeoni, S; Valente, Sergio; Massa, S; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF CHEMICAL INFORMATION AND MODELING (AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036) pp. 1420-1430 - issn: 1549-9596 - wos: WOS:000237658400053 (42) - scopus: 2-s2.0-33745356936 (46)
11573/366703 - 2006 -
One-Pot, High Yielding Synthesis of Novel Dihydrothiazolo[3,2-a]pyrimidinones Rotili, Dante; Mai, Antonello; Ambrogio, I; G., Fabrizi - 01a Articolo in rivista
paper: SYNTHETIC COMMUNICATIONS (New York, NY : Taylor & Francis
New York, NY: Marcel Dekker Incorporated) pp. 495-500 - issn: 0039-7911 - wos: WOS:000234819600013 (0) - scopus: 2-s2.0-31744445689 (1)
11573/363623 - 2006 -
6-Alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): Novel Regulators of Cell Differentiation and Proliferation Sbardella, G; Bartolini, S; Castellano, S; Artico, Marino; Paesano, N; Rotili, Dante; Spadafora, C; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1073-1080 - issn: 1860-7179 - wos: WOS:000202946300006 (13) - scopus: 2-s2.0-33750284393 (14)
11573/197018 - 2006 -
Nuove strategie per il superamento della farmaco-resistenza in Candida albicans Simonetti, Giovanna; Passariello, Claudio; N., Di Vincenzo; V., Sgherri; Mai, Antonello; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
book: 3° Congresso Nazionale della Società Italiana di Microbiologia Farmaceutica - ()
11573/365771 - 2005 -
3-(1H-Pyrrol-2-yl)-2-oxazolidinones as novel monoamine oxidase type A inhibitors. Mai, A; Artico, M.; Valente, S; Sbardella, G; Turini, P; Befani, O; Dalla Vedova, L; Agostinelli, E - 01a Articolo in rivista
paper: MEDICINAL CHEMISTRY (Bentham Science Publishers Ltd) pp. 117-124 - issn: 1573-4064 - wos: (0) - scopus: 2-s2.0-33846116762 (8)
11573/236120 - 2005 -
5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family Mai, Antonello; Artico, Marino; Ragno, Rino; Gianluca, Sbardella; Silvio, Massa; Chiara, Musiu; Massimo, Mura; Flavia, Marturana; Alessandra, Cadeddu; Giovanni, Maga; Paolo La, Colla - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 2065-2077 - issn: 0968-0896 - wos: WOS:000227576700017 (51) - scopus: 2-s2.0-13844316071 (55)
11573/526020 - 2005 -
Histone Deacetylation in Epigenetics: An Attractive Target for Anticancer Therapy Mai, Antonello; Massa, S; Rotili, Dante; Cerbara, I; Valente, Sergio; Pezzi, R; Simeoni, S; Ragno, Rino - 01a Articolo in rivista
paper: MEDICINAL RESEARCH REVIEWS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 261-309 - issn: 0198-6325 - wos: WOS:000228224900001 (303) - scopus: 2-s2.0-16844362441 (321)
11573/13036 - 2005 -
Synthesis and biological evaluation of 2-, 3-, and 4-acylaminocinnamyl-N-hydroxyamides as novel synthetic HDAC inhibitors. Mai, Antonello; S., Massa; R., Pezzi; P., Loidl; G., Brosch; Valente, Sergio - 01a Articolo in rivista
paper: MEDICINAL CHEMISTRY (Bentham Science Publishers Ltd) pp. 245-254 - issn: 1573-4064 - wos: (0) - scopus: 2-s2.0-25144492801 (27)
11573/364675 - 2005 -
Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides Mai, Antonello; Silvio, Massa; Riccardo, Pezzi; Silvia, Simeoni; Rotili, Dante; Angela, Nebbioso; Annamaria, Scognamiglio; Lucia, Altucci; Peter, Loidl; Gerald, Brosch - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3344-3353 - issn: 0022-2623 - wos: WOS:000228871700031 (189) - scopus: 2-s2.0-20944435415 (195)
11573/364679 - 2005 -
Exploring the connection unit in the HDAC inhibitor pharmacophore model: Novel uracil-based hydroxamates Mai, Antonello; Silvio, Massa; Rotili, Dante; Riccardo, Pezzi; Patrizia, Bottoni; Roberto, Scatena; Joachim, Meraner; Gerald, Brosch - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 4656-4661 - issn: 0960-894X - wos: WOS:000232465900002 (45) - scopus: 2-s2.0-25144444434 (48)
11573/364994 - 2005 -
Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (sirtuin) inhibitors Mai, Antonello; Silvio, Massa; Siva, Lavu; Riccardo, Pezzi; Silvia, Simeoni; Ragno, Rino; Mariotti, Francesca Romana; Chiani, Francesco; Camilloni, Giorgio; David A., Sinclair - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 7789-7795 - issn: 0022-2623 - wos: WOS:000233654900028 (152) - scopus: 2-s2.0-28144438533 (162)
11573/363627 - 2005 -
A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast Prisca, Ornaghi; Rotili, Dante; Gianluca, Sbardella; Mai, Antonello; Patrizia, Filetici - 01a Articolo in rivista
paper: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited
-London ; New York : Pergamon Press, 1958-) pp. 911-917 - issn: 0006-2952 - wos: WOS:000231663100011 (36) - scopus: 2-s2.0-23744453206 (38)
11573/364674 - 2005 -
6-[1-(2,6-difluorophenyl)ethyl]pyrimidinones antagonize cell proliferation and induce cell differentiation by inhibiting (a nontelomeric) endogenous reverse transcriptase Sara, Bartolini; Mai, Antonello; Artico, Marino; Nicola, Paesano; Rotili, Dante; Corrado, Spadafora; Gianluca, Sbardella - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6776-6778 - issn: 0022-2623 - wos: WOS:000233017300003 (51) - scopus: 2-s2.0-27444434731 (51)
11573/197017 - 2005 -
Attività di inibitori sintetici di istone deacetilasi sull'acquisizione di resistenza agli azolici in Candida albicans Simonetti, Giovanna; Passariello, Claudio; Mai, Antonello; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
book: 33° Congresso Nazionale Società Italiana di Microbiologia - ()
11573/240328 - 2004 -
Synthesis and biochemical evaluation of (R)-5-acyloxymethyl- and (S)-5-acylaminomethyl-3-(1H-pyrrol-1-yl)-2-oxazolidinones as new anti-monoamine oxidase (anti-MAO) agents. Mai, Antonello; Artico, Marino; Valente, Sergio; I., Cerbara; Befani, Olivia; Turini, Paola; L., Dalla Vedova; Agostinelli, Enzo - 01a Articolo in rivista
paper: ARKIVOC (ARKAT USA INC, C/O ALAN R KATRITZKY, UNIV FLORIDA, DEPT CHEMISTRY, PO BOX 117200, GAINESVILLE, USA, FL, 32611) pp. 23-43 - issn: 1551-7004 - wos: WOS:000222493900004 (6) - scopus: (0)
11573/13659 - 2004 -
Antimalarial and Antileishmanial Activities of Aroyl-pyrrolyl-hydroxy-amides, a New Class of Histone Deacetylase Inhibitors Mai, Antonello; I., Cerbara; Valente, Sergio; S., Massa; L. A., Walker; B. L., Tekwani - 01a Articolo in rivista
paper: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (American Society for Microbiology:PO Box 11127:Birmingham, AL 35201:(800)633-4931, (205)995-1567, EMAIL: asm.nonmembers.subs@ebsco.com, INTERNET: http://www.asm.org, Fax: (205)995-1588) pp. 1435-1436 - issn: 0066-4804 - wos: WOS:000220658600060 (49) - scopus: 2-s2.0-1642460965 (50)
11573/234811 - 2004 -
3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 2. Effect of Pyrrole-C2 and/or -C4 Substitutions on Biological Activity Mai, Antonello; S., Massa; I., Cerbara; Valente, Sergio; Ragno, Rino; P., Bottoni; R., Scatena; P., Loidl; G., Brosch - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1098-1109 - issn: 0022-2623 - wos: WOS:000189151500005 (60) - scopus: 2-s2.0-1242273835 (67)
11573/189567 - 2004 -
Synthesis and evaluation of sirtinol analogues as yeast Sir2 and human SIRT inhibitors Pezzi, R.; Rotili, D.; Simeoni, S.; Ragno, Rino; Mariotti, Francesca Romana; Chiani, Francesco; Camilloni, Giorgio; Massa, S.; Mai, Antonello - 04a Atto di comunicazione a congresso
book: XVIII International Symposium on Medicinal Chemistry - ()
11573/237666 - 2004 -
Computer-Aided Design, Synthesis, and Anti-HIV-1 Activity in Vitro of 2-Alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as Novel Potent Non-Nucleoside Reverse Transcriptase Inhibitors, Also Active Against the Y181C Variant Ragno, Rino; Mai, Antonello; G., Sbardella; Artico, Marino; S., Massa; C., Musiu; M., Mura; F., Marturana; A., Cadeddu; P., La Colla - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 928-934 - issn: 0022-2623 - wos: WOS:000188831300015 (82) - scopus: 2-s2.0-10744230514 (91)
11573/434777 - 2004 -
3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 3. Discovery of novel lead compounds through structure-based drug design and docking studies. Ragno, Rino; Mai, Antonello; Massa, S; Cerbara, I; Valente, Sergio; Bottoni, P; Scatena, R; Jesacher, F; Loidl, P; Brosch, G. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. - - issn: 0022-2623 - wos: WOS:000220038700008 (64) - scopus: 2-s2.0-12144291023 (69)
11573/884300 - 2004 -
Synthesis and in vitro antimycobacterial activity of novel 3-(1H-pyrrol-1-yl)-2-oxazolidinone analogues of PNU-100480 Sbardella, Gianluca; Mai, Antonello; Artico, Marino; Loddo, Roberta; Setzu, Maria Grazia; La Colla, Paolo - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 1537-1541 - issn: 0960-894X - wos: WOS:000220334000035 (63) - scopus: 2-s2.0-1542284725 (66)
11573/1147217 - 2004 -
New 6-nitroquinolones: synthesis and antimicrobial activities Sbardella, Gianluca; Mai, Antonello; Artico, Marino; Setzu, Maria Giovanna; Poni, Graziella; La Colla, Paolo - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001
Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 463-471 - issn: 0014-827X - wos: (0) - scopus: 2-s2.0-2642513828 (19)
11573/120507 - 2003 -
Synthesis and biological evaluation of enantiomerically pure pyrrolyl- oxazolidinones as a new class of potent and selective monoamine oxidase type A inhibitors. Mai, Antonello; Artico, Marino; M., Esposito; Ragno, Rino; G., Sbardella; S., Massa - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001
Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 231-241 - issn: 0014-827X - wos: (0) - scopus: 2-s2.0-0037373722 (25)
11573/218667 - 2003 -
3-(1H-pyrrol-2- and –3-yl)-2-oxazolidinones as novel potent and selective monoamine oxidase type A inhibitors. Mai, Antonello; Cervara, I.; Valente, Sergio; Artico, Marino; Sbardella, G.; Befani, Olivia; Turini, Paola; Agostinelli, Enzo - 13a Altro ministeriale
11573/204734 - 2003 -
3-(1H-pyrrol-2- and –3-yl)-2-oxazolidinones as novel potent and selective monoamine oxidase type A inhibitors. Mai, Antonello; I., Cervara; Valente, Sergio; Artico, Marino; G., Sbardella; Befani, Olivia; Turini, Paola; Agostinelli, Enzo - 04a Atto di comunicazione a congresso
book: 8th International Congress on Amino Acids and Proteins - ()
11573/366839 - 2003 -
Discovery of (Aryloxo propenyl)pyrrolyl Hydroxyamides as Selective Inhibitors of Class IIa Histone Deacetylase Homologue HD1-A Mai, Antonello; Massa, S.; Pezzi, R.; Rotili, Dante; Loidl, P.; Brosch, G. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4826-4829 - issn: 0022-2623 - wos: WOS:000186347400004 (61) - scopus: 2-s2.0-0242362600 (66)
11573/254722 - 2003 -
3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-alkylamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 1. Design, Synthesis, Biological Evaluation, and Binding Mode Studies Performed through Three Different Docking Procedures Mai, Antonello; S., Massa; Ragno, Rino; I., Cerbara; F., Jesacher; P., Loidl; G., Brosch - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 512-524 - issn: 0022-2623 - wos: WOS:000180836600008 (107) - scopus: 2-s2.0-0037434511 (121)
11573/53426 - 2003 -
Chemical Manipulations on 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-alkylamides, a New Class of Synthetic Histone Deacetylase Inhibitors: Towards an Histone Class Selectivity? Mai, Antonello; Silvio, Massa; Ilaria, Cerbara; Ragno, Rino; Peter, Loidl; Gerald, Brosch - 04a Atto di comunicazione a congresso
book: APOPTOSIS 2003 - ()
11573/884301 - 2003 -
Role of endogenous reverse transcriptase in murine early embryo development Pittoggi, Carmine; Sciamanna, Ilaria; Mattei, Elisabetta; Beraldi, Rosanna; Lobascio, Anna Maria; Mai, Antonello; Quaglia, Maria Giovanna; Lorenzini, Rodolfo; Spadafora, Corrado - 01a Articolo in rivista
paper: MOLECULAR REPRODUCTION AND DEVELOPMENT (New York N.Y.: Wiley) pp. 225-236 - issn: 1040-452X - wos: WOS:000185632800003 (64) - scopus: 2-s2.0-0141571160 (61)
11573/53414 - 2002 -
Synthesis and Biological Evaluation of Enantiomerically Pure 3-(1H-Pyrrol-1-yl)-2-oxazolidinones as a New Class of Potent and Selective Monoamine Oxidase Type A Inhibitors G., Sbardella; Mai, Antonello; Artico, Marino; S., Massa; Ragno, Rino; M., Esposito; O., Befani; V., Giovannini; B., Mondov - 04a Atto di comunicazione a congresso
book: XVIIth International Symposium on Medical Chemistry - ()
11573/252009 - 2002 -
3-(1H-pyrrol-1-yl)-2-oxazolidinones as reversible, highly potent, and selective inhibitors of monoamine oxidase type A. Mai, Antonello; Artico, M.; Esposito, M.; Sbardella, G.; Massa, S.; Befani, O.; Turini, Paola; Giovannini, V.; Mondovi', Bruno - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1180-1183 - issn: 0022-2623 - wos: WOS:000174506200003 (49) - scopus: 2-s2.0-0037075787 (49)
11573/53416 - 2002 -
Computer-Aided Design of Novel Aroyl-pyrrolyl-hydroxy-alkylamide (APHA) Derivatives as New Synthetic Histone Deacetylase Inhibitors Mai, Antonello; I., Cerbara; S., Massa; Ragno, Rino; G., Sbardella; F., Jesacher; P., Loidl; G., Brosch - 04a Atto di comunicazione a congresso
book: XVIIth International Symposium on Medical Chemistry - ()
11573/254380 - 2002 -
Binding Mode Analysis of 3-(4-Benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: a New Synthetic Histone Deacetylase Inhibitor Inducing Histone Hyperacetylation, Growth Inhibition, and Terminal Cell Differentiation Mai, Antonello; Massa, S.; Ragno, Rino; Esposito, M.; Sbardella, G.; Nocca, G.; Scatena, R.; Jesacher, F.; Loidl, P.; Brosch, G. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1778-1784 - issn: 0022-2623 - wos: WOS:000175168700006 (64) - scopus: 2-s2.0-0037171823 (70)
11573/12979 - 2001 -
A new facile and expeditious synthesis of N-hydroxy-N\'-phenyloctanediamide, a potent inducer of terminal cytodifferentiation Mai, Antonello; Esposito, M; Sbardella, G; Massa, S. - 01a Articolo in rivista
paper: ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL (Organic Preparations and Procedures Incorporated:PO Box 610009:Newton Highlands, MA 02161:(617)287-6130, EMAIL: jp.anselme@umb.edu, Fax: (617)287-6030) pp. 391-394 - issn: 0030-4948 - wos: WOS:000169959200013 (54) - scopus: 2-s2.0-0035536590 (57)
11573/248287 - 2001 -
Structure-Based Design, Synthesis and Biological Evaluation of Conformationally Restricted Novel 2-Alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as Non-nucleoside Inhibitors of HIV-1 Reverse Transcriptase Mai, Antonello; Sbardella, G; Artico, Marino; Ragno, Rino; Massa, S; Novellino, E; Greco, G; Lavecchia, A; Musiu, C; La Colla, M; Murgioni, C; La Colla, P. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2544-2554 - issn: 0022-2623 - wos: WOS:000170167700007 (85) - scopus: 2-s2.0-0035797356 (97)
11573/13654 - 2001 -
3,4-Dihydro-2-alkoxy-6-benzyl-oxopyrimidines (DABOs): Development of a Potent Class of Non-nucleoside Reverse Transcriptase Inhibitors Marongiu, M. E.; Pani, A.; Musiu, C.; La Colla, P.; Mai, Antonello; Sbardella, G.; Massa, S.; Artico, M. - 02a Capitolo o Articolo
book: Recent developments in antiviral research - (817895012X)
11573/12978 - 2001 -
3-(4-aroyl-1h-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors Massa, S; Mai, Antonello; Sbardella, G; Esposito, M; Ragno, Rino; Loidl, P; Brosch, G. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2069-2072 - issn: 0022-2623 - wos: WOS:000169367000004 (73) - scopus: 2-s2.0-0035927427 (82)
11573/13590 - 2001 -
DABOs as candidates to prevent mucosal HIV transmission Pani, A; Musiu, C; Loi A., G; Mai, Antonello; Loddo, R; La Colla, P; Marongiu, M. E. - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 51-59 - issn: 0956-3202 - wos: (0) - scopus: 2-s2.0-0034815526 (27)
11573/253561 - 2001 -
Chiral resolution and molecular modeling investigation of rac-2-cyclopentylthio-6-[1-(2,6-difluorophenyl)ethyl]-3,4-dihydro-5- methylpyrimidin-4(3H)-one (MC-1047), a potent anti-HIV-1 reverse transcriptase agent of the DABO class. Quaglia, M. G.; Mai, Antonello; Sbardella, G.; Artico, Marino; Ragno, Rino; Massa, S.; Del Piano, D.; Setzu, G.; Doratiotto, S.; Cotichini, V. - 01a Articolo in rivista
paper: CHIRALITY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 75-80 - issn: 0899-0042 - wos: WOS:000166596300002 (27) - scopus: 2-s2.0-0035146092 (31)
11573/255442 - 2001 -
Structure-activity relationship studies on new DABOs: effect of substitutions at pyrimidine C-5 and C-6 positions on anti-HIV-1 activity Sbardella, G.; Mai, Antonello; Artico, M.; Chimenti, Paola; Massa, S.; Loddo, R.; Marongiu, M. E.; La Colla, P.; Pani, A. - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 37-50 - issn: 0956-3202 - wos: WOS:000176040800002 (28) - scopus: 2-s2.0-0034975054 (29)
11573/254785 - 2000 -
Does the 2-methylthiomethyl substituent really confer high anti-HIV-1 activity to S-DABOs ? Sbardella, G; Mai, Antonello; Artico, Marino; Massa, S; Marceddu, T; Vargiu, L; Marongiu M., E; La Colla, P. - 01a Articolo in rivista
paper: MEDICINAL CHEMISTRY RESEARCH (Birkhauser Boston Incorporated:c/o Springer Verlag, PO Box 2485:Secaucus, NJ 07096:(800)777-4643, (973)348-4033, Fax: (973)348-4505) pp. 30-39 - issn: 1054-2523 - wos: (0) - scopus: 2-s2.0-0033943608 (28)
11573/247380 - 1999 -
Nitroquinolones with Broad-Spectrum Antimycobacterial Activity in Vitro. Artico, Marino; Mai, Antonello; Sbardella, G; Massa, S; Musiu, C; Lostia, S; Demontis, F; La Colla, P. - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 1651-1656 - issn: 0960-894X - wos: WOS:000080896500005 (24) - scopus: 2-s2.0-0033591758 (33)
11573/256812 - 1999 -
5-alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3,4-dihydropyrimidin-4(3h)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives Mai, Antonello; Artico, Marino; Sbardella, G.; Massa, S.; Novellino, E.; Greco, G.; Loi, A. G.; Tramontano, E.; Marongiu, M. E.; La Colla, P. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 619-627 - issn: 0022-2623 - wos: WOS:000078826300011 (108) - scopus: 2-s2.0-0033602141 (123)
11573/256998 - 1999 -
N-[4-(1,1'-Biphenylyl)methyl]-4-(4-thiomorpholinylmethyl)benzenamines, a New Class of Synthetic Antituberculosis Agents Active Against Mycobacterium Avium. Mai, Antonello; Sbardella, G.; Artico, Marino; Massa, S.; Lampis, G.; Deidda, D.; Pompei, R. - 01a Articolo in rivista
paper: MEDICINAL CHEMISTRY RESEARCH (Birkhauser Boston Incorporated:c/o Springer Verlag, PO Box 2485:Secaucus, NJ 07096:(800)777-4643, (973)348-4033, Fax: (973)348-4505) pp. 149-161 - issn: 1054-2523 - wos: WOS:000080663900001 (1) - scopus: 2-s2.0-0032996022 (1)
11573/242616 - 1998 -
CRYSTAL STRUCTURE OF 2-[5-(4-CARBETOXYPHENOXY)PENTANOYL]-5-CHLOROTHIOPHENE, C18H19O4ClS A., Ettorre; Artico, Marino; Mai, Antonello; Ragno, Rino; Porretta, Giulio Cesare; S., Massa - 01a Articolo in rivista
paper: ZEITSCHRIFT FUR KRISTALLOGRAPHIE (R Oldenbourg Verlag:Rosenheimerstrasse 145, D 81671 Munich Germany:011 49 89 45051229, INTERNET: http://www.oldenbourg.de, Fax: 011 49 89 45051207) pp. 129-130 - issn: 0044-2968 - wos: (0) - scopus: (0)
11573/257184 - 1998 -
N-[4-(1,1'-Biphenyl)methyl]-4-(4-thiomorpholinylmethyl)benzenamines as non-oxazolidinone analogues of antimycobacterial U-100480. Artico, Marino; Mai, Antonello; Sbardella, G; Massa, S; Lampis, G; Deidda, D; Pompei, R. - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 1493-1498 - issn: 0960-894X - wos: WOS:000074291800010 (16) - scopus: 2-s2.0-0032537533 (20)
11573/12752 - 1998 -
crystal structure of 3,4-dihydro-6-(3\'-methylbenzyl)-2-((1-methylpropyl)thio)-4-oxopyrimidine (S-dabo 618), C16H20N2OS and 3,4-dihydro-2-((1-methylpropyl)thio)-6-(2-naphthylmethyl)-4-oxopyrimidine (datno 774), C19H20N2OS, two HIV-1 reverse transcriptase inhibitors Ettorre, A; Mai, Antonello; Sbardella, G; Artico, M; La Colla, P; Massa, S. - 01a Articolo in rivista
paper: ZEITSCHRIFT FUR KRISTALLOGRAPHIE (R Oldenbourg Verlag:Rosenheimerstrasse 145, D 81671 Munich Germany:011 49 89 45051229, INTERNET: http://www.oldenbourg.de, Fax: 011 49 89 45051207) pp. 593-595 - issn: 0044-2968 - wos: WOS:000074680700076 (4) - scopus: (0)
11573/1147212 - 1997 -
Arylketotetramethylene analogues of disoxaril with anti-human rhinovirus 14 activity Mai, A.; Artico, M.; Sbardella, G.; Massa, S.; De Montis, Andrea; Puddu, I.; Musiu, C.; La Colla, P. - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 235-242 - issn: 0956-3202 - wos: WOS:A1997WY39600007 (1) - scopus: 2-s2.0-0031009277 (2)
11573/12973 - 1997 -
dihydro(alkylthio)(naphthylmethyl)oxopyrimidines: novel non-nucleoside reverse transcriptase inhibitors of the S-DABO series Mai, Antonello; Artico, M; Sbardella, G; Quartarone, S; Massa, S; Loi A., G; De Montis, A; Scintu, F; Putzolu, M; La Colla, P. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1447-1454 - issn: 0022-2623 - wos: WOS:A1997WY39500005 (111) - scopus: 2-s2.0-15444340492 (125)
11573/244117 - 1996 -
Investigation on QSAR and Binding Mode of a New Class of Human Rhinovirus-14 Inhibitors by CoMFA and Docking Experiments. Artico, Marino; M., Botta; F., Corelli; Mai, Antonello; S., Massa; Ragno, Rino - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 1715-1724 - issn: 0968-0896 - wos: WOS:A1996VU12500017 (8) - scopus: 2-s2.0-0030272824 (10)
11573/247245 - 1996 -
6-(3-methylbenzyl)-2-(2-methylpropyl)thio-4(3h)-pyrimidinone (dabo 622) Ettorre, A; Mai, Antonello; Artico, Marino; Massa, S; De Montis, A; La Colla, P. - 01a Articolo in rivista
paper: ACTA CRYSTALLOGRAPHICA. SECTION C, CRYSTAL STRUCTURE COMMUNICATIONS (Blackwell Munksgaard:PO Box 2148, Periodicals Department, DK-1016 Copenhagen K Denmark:011 45 33 755913, EMAIL: agentservices@oxon.blackwellpublishing.com, INTERNET: http://www.blackwellmunksgaard.com, Fax: 011 45 77 333377) pp. 2115-2117 - issn: 0108-2701 - wos: WOS:A1996VG08200099 (14) - scopus: 2-s2.0-0030213813 (16)
11573/247246 - 1996 -
Methyl-2-thienylketopolymethyleneoxyphenyl derivatives of alkyl-substituted 4,5-dihydro-oxazoles with anti-human picornavirus activity. Mai, Antonello; Artico, Marino; S., Massa; Ragno, Rino; A., De Montis; S., Corrias; M. G., Spiga; P., La Colla - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 213-220 - issn: 0956-3202 - wos: WOS:A1996UX10500007 (3) - scopus: 2-s2.0-0029901071 (3)
11573/246586 - 1995 -
Synthesis and anti-HIV-1 Activity of Thio Analogues of Dihydro alkoxybenzyl oxopyrimidines Mai, Antonello; Artico, Marino; Sbardella, G; Massa, S; Loi A., G; Tramontano, E; Scano, P; La Colla, P. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3258-3263 - issn: 0022-2623 - wos: (0) - scopus: 2-s2.0-0029095334 (113)
11573/246108 - 1995 -
Pyrrolobenzodiazepines with antinociceptive activity: synthesis and pharmacological activities. Mai, Antonello; Di Santo, Roberto; Massa, S.; Artico, Marino; Pantaleoni, G. C.; Giorgi, R.; Coppolino, M. F.; Barracchini, A. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 593-601 - issn: 0223-5234 - wos: WOS:A1995RK67200008 (15) - scopus: 2-s2.0-0029075894 (17)
11573/12749 - 1995 -
(((thienylcarbonyl)alkyl)oxy)phenyl)- and (((pyrrylcarbonyl)alkyl)oxy)phenyl)oxazoline derivatives with potent and selective antihuman rhinovirus activity Massa, S; Corelli, F; Mai, Antonello; Ragno, Rino; De Montis, A; Loi A., G; Corrias, S; Marongiu M., E; La Colla, P.; Artico, Marino - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 803-809 - issn: 0022-2623 - wos: WOS:A1995QL25400007 (6) - scopus: 2-s2.0-0028923893 (7)
11573/244102 - 1995 -
synthesis and antiviral activity of new 3,4-dihydro-2-alkoxy-6-benzyl-4-oxopyrimidines (DABOs), specific inhibitors of human immunodeficiency virus type 1 Massa, S; Mai, Antonello; Artico, Marino; Sbardella, G; Tramontano, E. E.; Loi, A. G.; Scano, P; La Colla, P. - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 1-8 - issn: 0956-3202 - wos: WOS:A1995QA06000001 (62) - scopus: 2-s2.0-0028869436 (68)
11573/246474 - 1995 -
Comparative Molecular Field Analysis of New Human Rhinovirus-14 Inhibitors Ragno, Rino; M., Botta; F., Corelli; Mai, Antonello; S., Massa; G. C., Porretta; M., Artico - 02a Capitolo o Articolo
book: QSAR AND MOLECULAR MODELLING: CONCEPTS, COMPUTATIONAL TOOLS AND BIOLOGICAL APPLICATIONS - ()
11573/247326 - 1994 -
ANTIFUNGAL AGENTS .7. DICHLOROPHENYLPYRRYLIMIDAZOLYLMETHANE DERIVATIVES - SYNTHESIS AND ANTIFUNGAL ACTIVITIES Massa, S.; Mai, Antonello; Ragno, Rino; Porretta, G. C.; Retico, A.; Simonetti, Giovanna; Artico, M. - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001
Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 51-55 - issn: 0014-827X - wos: WOS:A1994NB74600007 (1) - scopus: 2-s2.0-0028302844 (1)
11573/12688 - 1994 -
Characterization of the anti-HIV-1 activity of 3,4-dihydro-2-alkoxy-6-benzyl-4-oxopyrimidines (DABOs), new non-nucleoside reverse transcriptase inhibitors Tramontano, E; Marongiu M., E; De Montis, A; Loi A., G; Artico, M; Massa, S; Mai, Antonello; La Colla, P. - 01a Articolo in rivista
paper: NEW MICROBIOLOGICA (-Pavia : Edizioni Internazionali, 2004
precedente:
-Bologna: Luigi Ponzio e figlio) pp. 269-279 - issn: 1121-7138 - wos: (0) - scopus: 2-s2.0-0028522917 (35)
11573/14239 - 1993 -
3,4-dihydro-2-alkoxy-6-benzyl-4-oxopyrimidines (DABOs): a new class of specific inhibitors of human immunodeficiency virus type 1 Artico, M; Massa, S; Mai, Antonello; Marongiu M., E; Piras, G; Tramontano, E; La Colla, P. - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 361-368 - issn: 0956-3202 - wos: WOS:A1993ME94900008 (92) - scopus: 2-s2.0-0027521797 (97)
11573/247026 - 1993 -
Antifungal Agents. 4. Synthesis of neo-Isopyrrolnitrin and other 3-Aryl-4-nitro-1H-pyrroles via TosMIC. Massa, S; Di Santo, Roberto; Costi, Roberta; Mai, Antonello; Artico, M; Retico, A; Apuzzo, G; Artico, M; Simonetti, Giovanna - 01a Articolo in rivista
paper: MEDICINAL CHEMISTRY RESEARCH (Birkhauser Boston Incorporated:c/o Springer Verlag, PO Box 2485:Secaucus, NJ 07096:(800)777-4643, (973)348-4033, Fax: (973)348-4505) pp. 192-199 - issn: 1054-2523 - wos: (0) - scopus: (0)
11573/247239 - 1993 -
5,6-dihydro-4H-pyrrolo(1,2-a)(1,4)benzodiazepine-4,4-diacetic acid diethyl ester, an useful synthon for the synthesis of new polycyclic nitrogen systems of pharmacological interest Massa, S; Mai, Antonello; Di Santo, Roberto; Artico, M. - 01a Articolo in rivista
paper: JOURNAL OF HETEROCYCLIC CHEMISTRY (Hetero Corporation:PO Box 170:Provo, UT 84603:(801)400-7373, EMAIL: jhetchem@yahoo.com, Fax: (801)356-7373) pp. 897-903 - issn: 0022-152X - wos: WOS:A1993MD59700009 (6) - scopus: 2-s2.0-0027453311 (8)
11573/14961 - 1993 -
Synthesis and antifungal activities of aryl-1H-pyrrol-2-yl-1H-imidazol-1-yl-methane derivatives with unsaturated chains Massa, S; Ragno, Rino; Porretta G., C; Mai, Antonello; Retico, A; Artico, M; Simonetti, N. - 01a Articolo in rivista
paper: ARCHIV DER PHARMAZIE (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 539-546 - issn: 0365-6233 - wos: WOS:A1993MB51500008 (12) - scopus: 2-s2.0-0027525303 (9)
11573/14962 - 1992 -
one-pot synthesis of novel spiro-annelated pyrrole-containing heterocyclic system from suitable synthons Artico, M; Massa, S; Mai, Antonello; Silvestri, R; Stefancich, G. - 01a Articolo in rivista
paper: JOURNAL OF HETEROCYCLIC CHEMISTRY (Hetero Corporation:PO Box 170:Provo, UT 84603:(801)400-7373, EMAIL: jhetchem@yahoo.com, Fax: (801)356-7373) pp. 241-245 - issn: 0022-152X - wos: (0) - scopus: (0)
11573/14963 - 1992 -
pyrrolobenzodiazepines and related systems. 2. synthesis and biological properties of isonoraptazepine derivatives Massa, S; Artico, M; Mai, Antonello; Corelli, F; Botta, M; Tafi, A; Pantaleoni, G. C.; Giorgi, R; Coppolino, M. F.; Cagnotto, A; Skorupska, M. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4533-4541 - issn: 0022-2623 - wos: WOS:A1992KA52000004 (21) - scopus: 2-s2.0-0027052394 (22)
11573/14543 - 1992 -
synthesis of pyrazole analogues of isoaptazepine Massa, S; Artico, M; Mai, Antonello; Mancuso, A; Corelli, F. - 01a Articolo in rivista
paper: JOURNAL OF HETEROCYCLIC CHEMISTRY (Hetero Corporation:PO Box 170:Provo, UT 84603:(801)400-7373, EMAIL: jhetchem@yahoo.com, Fax: (801)356-7373) pp. 1851-1854 - issn: 0022-152X - wos: (0) - scopus: (0)
11573/257032 - 1992 -
Pyrrylphenylethanones Related to Cathinone and Lefetamine : Synthesis and Pharmacological Activities. Massa, S; Di Santo, Roberto; Mai, Antonello; Artico, M; Pantaleoni G., C; Giorgi, R; Coppolino, M. F. - 01a Articolo in rivista
paper: ARCHIV DER PHARMAZIE (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 403-409 - issn: 0365-6233 - wos: WOS:A1992JF69600006 (2) - scopus: 2-s2.0-0026655175 (3)
11573/245036 - 1991 -
Synthesis of New Disoxaril Analogues with Potent and Selective Anti-Human Rhinovirus 14 Activity S., Massa; M., Artico; Mai, Antonello; Ragno, Rino; F., Corelli; A., Pani; M. E., Marongiu; E., Tramontano; P., La Colla - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 575-578 - issn: 0960-894X - wos: (0) - scopus: 2-s2.0-0026045626 (5)
11573/247522 - 1990 -
Synthesis and Antimicrobial and Cytotoxic Activities of Pyrrole-containing Analogues of Trichostatin A. Massa, S.; Artico, M.; Corelli, F.; Mai, Antonello; Di Santo, Roberto; Cortes, S.; Marongiu, M. E.; Pani, A.; La Colla, P. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2845-2849 - issn: 0022-2623 - wos: WOS:A1990EA37400026 (27) - scopus: 2-s2.0-0025102721 (29)
11573/14236 - 1990 -
pyrrolobenzodiazepine and related systems. I. synthesis and pharmacological evaluation of new 5,6-dihydro-4H-pyrrolo(1,2-a)(1,4)benzodiazepine derivatives Massa, S; Artico, M; Mai, Antonello; Corelli, F; Pantaleoni G., C; Giorgi, R; Ottaviani, D; Cagnotto, A. - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001
Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 1265-1281 - issn: 0014-827X - wos: WOS:A1990ET90100002 (11) - scopus: 2-s2.0-0025666693 (11)
11573/14309 - 1990 -
spiro-(4H-pyrrolo(1,2-a)(1,4)benzodiazepine-4,4\'-piperidine)derivatives as potential nootropic agents: a simple one-pot synthesis Massa, S; Mai, Antonello; Artico, M. - 01a Articolo in rivista
paper: SYNTHETIC COMMUNICATIONS (New York, NY : Taylor & Francis
New York, NY: Marcel Dekker Incorporated) pp. 3537-3545 - issn: 0039-7911 - wos: WOS:A1990FD73600018 (10) - scopus: (0)
11573/13360 - 1990 -
heterocyclic system. XI. synthesis of 1H,4H-pyrazolo(4,3-b)pyrrolizine and 2H,4H-pyrazolo(4,3-b)pyrrolizine derivatives Massa, S; Mai, Antonello; Artico, M; Corelli, F. - 01a Articolo in rivista
paper: JOURNAL OF HETEROCYCLIC CHEMISTRY (Hetero Corporation:PO Box 170:Provo, UT 84603:(801)400-7373, EMAIL: jhetchem@yahoo.com, Fax: (801)356-7373) pp. 1805-1808 - issn: 0022-152X - wos: WOS:A1990EF97000053 (6) - scopus: 2-s2.0-0025081354 (7)
11573/470241 - 1990 -
Research on antibacterial and antifungal agents. XIII. Synthesis and antimicrobial activity of 1-arylmethyl-4-aryl-1H-pyrrole-3-carboxylic acids Silvio, Massa; Di Santo, Roberto; Mai, Antonello; M., Botta; Artico, Marco; S., Panico; Giovanna, Simonetti - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001
Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 833-846 - issn: 0014-827X - wos: WOS:A1990EA52000002 (20) - scopus: 2-s2.0-0025153041 (18)
11573/14308 - 1989 -
acidi 5-aroil-5,6-diidro-4H-pirrolo(1,2-a)(1,4)benzodiazepin-4-carbossilici: sintesi ed attività analgesica e neurocomportamentale Massa, S; Corelli, F; Artico, M; Mai, Antonello; Silvestri, R. - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001
Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 109-123 - issn: 0014-827X - wos: WOS:A1989U409700002 (12) - scopus: 2-s2.0-0024473787 (10)
11573/14235 - 1989 -
research on antibacterial and antifungal agents. XI. new antibacterial quinolones related to pirfloxacin Massa, S; Corelli, F; Mai, Antonello; Artico, M; Panico, S; Simonetti, N. - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001
Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 779-793 - issn: 0014-827X - wos: WOS:A1989AV95900002 (4) - scopus: 2-s2.0-0024424105 (4)
11573/14234 - 1989 -
syntheses of 3b,4,6,7-tetrahydro-5H,9H-pyrazino(2,1-c)pyrrolo(1,2-a)(1,4)benzodiazepine, a valuable precursor of potential central nervous system agents Massa, S; Mai, Antonello; Artico, M; Corelli, F; Botta, M. - 01a Articolo in rivista
paper: TETRAHEDRON (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 2763-2772 - issn: 0040-4020 - wos: WOS:A1989U501500024 (22) - scopus: (0)
11573/14241 - 1989 -
synthesis and antifungal activities of 1-(p-methyl-a-(4-(1H-pyrrol-1-yl)phenyl)benzyl)azoles and some related products Massa, S; Stefancich, G; Corelli, F; Silvestri, R; Mai, Antonello; Artico, M; Panico, S; Simonetti, N. - 01a Articolo in rivista
paper: ARCHIV DER PHARMAZIE (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 369-373 - issn: 0365-6233 - wos: (0) - scopus: 2-s2.0-0024678155 (14)
11573/14240 - 1988 -
synthesis of a new tetracyclic system related to aptazapine (CGS 7525A) by one-pot double annelation Massa, S; Mai, Antonello; Corelli, F. - 01a Articolo in rivista
paper: TETRAHEDRON LETTERS (Oxford; New York; Paris; Frankfurt: Pergamon Press, 1959-) pp. 6471-6474 - issn: 0040-4039 - wos: WOS:A1988R414700025 (14) - scopus: 2-s2.0-0024239164 (14)
11573/14960 - 1987 -
vitamina C: attività a livello del sistema nervoso centrale Barretta, V.; Mai, Antonello - 01a Articolo in rivista
paper: GIORNALE DI MEDICINA MILITARE (M D Uff AMM Spec G Medicina MI:via Marsala 104, 00185 Rome Italy:011 39 6 47357939) pp. 223-227 - issn: 0017-0364 - wos: (0) - scopus: (0)
11573/14233 - 1987 -
ricerche su composti antibatterici ed antifungini. Nota VIII - sintesi ed attività antifungina di derivati pirrolici correlati con la tricostatina A Corelli, F; Massa, S; Stefancich, G; Mai, Antonello; Artico, M; Panico, S; Simonetti, N. - 01a Articolo in rivista
paper: IL FARMACO. EDIZIONE SCIENTIFICA (Editoriale II Farmaco:PO Box 227, 27100 Pavia Italy:(0382)23.061) pp. 893-903 - issn: 0430-0920 - wos: WOS:A1987M184000003 (9) - scopus: 2-s2.0-0023554206 (9)
11573/14232 - 1986 -
cromatografia: aspetti termodinamici Barretta, V.; Mai, Antonello - 01a Articolo in rivista
paper: GIORNALE DI MEDICINA MILITARE (M D Uff AMM Spec G Medicina MI:via Marsala 104, 00185 Rome Italy:011 39 6 47357939) pp. 448-451 - issn: 0017-0364 - wos: (0) - scopus: (0)