ANTONELLO MAI

Full professor

email: antonello.mai@uniroma1.it
phone: 0649913392
building: CU019
room: 152

NAME POSITION TITLE
ANTONELLO MAI FULL PROFESSOR

EDUCATION/TRAINING
INSTITUTION AND LOCATION DEGREE YEAR(S) FIELD OF STUDY
Sapienza University of Rome Pharmacy 1984 Pharmacy
Sapienza University of Rome PhD 1992 Medicinal Chemistry

RESEARCH AND PROFESSIONAL EXPERIENCE:
Positions
1987 Institute Pasteur-Cenci Bolognetti Foundation Fellow, Sapienza University of Rome
1988-1992 PhD student, Dept Medicinal Chemistry studies, Sapienza University of Rome
1990-1998 Technical Researcher, Dept Medicinal Chemistry studies, Sapienza University of Rome
1998-2011 Associate Professor, Dept Drug Chemistry and Technologies, Sapienza University of Rome
2011-today Full Professor, Dept Drug Chemistry and Technologies, Sapienza University of Rome

Honors
From 1992 member of Italian Chemical Society (SCI)
From 2003 Regional Editor of the ‘Mini Reviews in Medicinal Chemistry” (Bentham) and “Medicinal Chemistry” (Bentham)
2004-2009 member of the Executive Committee of the SCI Medicinal Chemistry Division
From 2008 member of the Scientific Committee of the PhD commission for the PhD course “Medicinal Chemistry” at Sapienza University of Rome.
2009-2015 member of the Scientific Committee of the European School of Medicinal Chemistry (ESMEC)
2010 member of the International Advisory Board for “ChemMedChem”, Wiley eds.
2012-2018 President of the Scientific Committee of the commission for the PhD course “Medicinal Chemistry” at Sapienza University of Rome.
2013-2019 President of the Degree Course in “Medicinal Chemistry and Technology”, Sapienza University of Rome.
From 2014: Member of the Sapienza Commission for accreditation of PhD Courses
From 2015: Chair Editor of “ChemMedChem”.
From 2016: System Expert of ANVUR for accreditation of italian Atenei
From 2018: Associate Editor of “Clinical Epigenetics” and “Journal of Enzyme Inhibition and Medicinal Chemistry”
2014-2022: Member of the Sapienza Commission for accreditation of PhD Courses

Prof. Antonello Mai is a professor of the following courses at the Faculty of Pharmacy and Medicine of Sapienza University of Rome involving Medicinal Chemistry: Medicinal Chemistry 1, Medicinal Chemistry 2, Medicinal Chemistry 3, Medicinal Chemistry and Toxicology Analysis, Pharmaceutical Biotechnology.
He has great expertise in 1) organic synthesis; 2) synthesis of new potential bio-active compounds, particularly in the field of epigenetics (inhibitors of DNMTs, HDACs [unselective and class-selective], HATs, sirtuins (inhibitors and activators), PRMTs, HKMTs, and KDMs), anticancer agents, antiviral agents (anti-human picornavirus compounds (disoxaril analogues), and anti-HIV-1 compounds belonging to the non-nucleoside reverse transcriptase inhibitor classes (DABOs, S-DABOs, DATNOs, F2-S-DABOs, Amino-DABOs), antibacterial (oxacine analogues), antimycobacterial (oxacine and U-100480 analogues) and antifungal (trichostatin A, pyrrolnitrin, and bifonazole analogues) agents, and CNS agents (pyrrolobenzodiazepines active as analgesic, antidepressant and nootropic compounds); 3) development of new methodology for the synthesis of heterocycles; 4) analysis and purification of organic mixtures; 5) study and characterization of organic molecules.

Scientific qualification (source: Scopus):
H-index: 64 (05.09.23)
n. publications: 358 (05.09.23)
n. Citations: 14,753 (05.09.23)

Last projects approved for funding:
2022 research project: Pasteur Institute - Cenci Bolognetti Foundation, two-year (2021-2022) project, title: “Epi-drugs for treatment of parasitic diseases”; role: Principal Investigator (PI). 40,000 euro.
2021 research project: Fondo Integrativo Speciale per la Ricerca (FISR) 2019, title: “Methylome Dysregulation in Cancer: a Synergistic Multidisciplinary Approach for Fighting (MeDyCa); role: Principal Investigator. 673,600 euro.
2017 research project: NIH 2017-2020, title: “Histone Lysine deMethylation: Structures, Inhibitions and Mechanisms (Project 00006104)”; role: co-investigator. $ 107,036.
2016 research project: AIRC 2016-2019, title: “Targeting histone demethylation for cancer therapy: development of new LSD1 inhibitors”; role: Principal Investigator. 286,000 euro.
2015 research project: PRIN (from Italian Government) 2015, title: “Epitargeting of Acute Myeloid Leukemia: a Synergistic Multidisciplinary Approach”; role: Principal Investigator. 81,500 euro.

Selected Last 3-years Peer-reviewed Publications
1. Fiorentino F, Menna M, Rotili D, Valente S, Mai A. METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. J Med Chem. 2023 Jan 24. doi: 10.1021/acs.jmedchem.2c01601. PMID: 36370994.
2. Negri A, Marozzi M, Trisciuoglio D, Rotili D, Mai A, Rizzi F. Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2163242. doi: 10.1080/14756366.2022.2163242.
3. Zhou J, Horton JR, Menna M, Fiorentino F, Ren R, Yu D, Hajian T, Vedadi M, Mazzoccanti G, Ciogli A, Weinhold E, Hüben M, Blumenthal RM, Zhang X, Mai A, Rotili D, Cheng X. Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. J Med Chem. 2023 Jan 12;66(1):934-950. doi: 10.1021/acs.jmedchem.2c01789.
4. Di Bello E, Sian V, Bontempi G, Zwergel C, Fioravanti R, Noce B, Castiello C, Tomassi S, Corinti D, Passeri D, Pellicciari R, Mercurio C, Varasi M, Altucci L, Tripodi M, Strippoli R, Nebbioso A, Valente S, Mai A. Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells. Eur J Med Chem. 2023 Feb 5;247:115022. doi: 10.1016/j.ejmech.2022.115022.
5. Orekhova A, De Angelis M, Cacciotti A, Reverberi M, Rotili D, Giorgi A, Protto V, Bonincontro G, Fiorentino F, Zgoda V, Mai A, Palamara AT, Simonetti G. Modulation of Virulence-Associated Traits in Aspergillus fumigatus by BET Inhibitor JQ1. Microorganisms. 2022 Nov 18;10(11):2292. doi: 10.3390/microorganisms10112292.
6. Zwergel C, Fioravanti R, Mai A. PD-L1 small-molecule modulators: A new hope in epigenetic-based multidrug cancer therapy? Drug Discov Today. 2023 Feb;28(2):103435. doi: 10.1016/j.drudis.2022.103435.
7. Bontempi G, Terri M, Garbo S, Montaldo C, Mariotti D, Bordoni V, Valente S, Zwergel C, Mai A, Marchetti A, Domenici A, Menè P, Battistelli C, Tripodi M, Strippoli R. Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells. Cell Death Dis. 2022 Nov 17;13(11):965. doi: 10.1038/s41419-022-05398-0.
8. Noce B, Di Bello E, Zwergel C, Fioravanti R, Valente S, Rotili D, Masotti A, Ansari MSZ, Trisciuoglio D, Chakrabarti A, Romier C, Robaa D, Sippl W, Jung M, Häberli C, Keiser J, Mai A. Chemically Diverse S. mansoni HDAC8 Inhibitors Reduced Viability in Worm Larval and Adult Stages. ChemMedChem. 2022 Oct 17. doi: 10.1002/cmdc.202200510.
9. Suenkel B, Valente S, Zwergel C, Weiss S, Di Bello E, Fioravanti R, Aventaggiato M, Amorim JA, Garg N, Kumar S, Lombard DB, Hu T, Singh PK, Tafani M, Palmeira CM, Sinclair D, Mai A, Steegborn C. Potent and Specific Activators for Mitochondrial Sirtuins Sirt3 and Sirt5. J Med Chem. 2022, 65(20),14015-14031. doi: 10.1021/acs.jmedchem.2c01215.
10. Ansari MSZ, Stagni V, Iuzzolino A, Rotili D, Mai A, Del Bufalo D, Lavia P, Degrassi F, Trisciuoglio D. Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells. Cancer Gene Ther. 2022 Sep 18. doi: 10.1038/s41417-022-00524-8.
11. Chianese U, Papulino C, Passaro E, Evers TM, Babaei M, Toraldo A, De Marchi T, Niméus E, Carafa V, Nicoletti MM, Del Gaudio N, Iaccarino N, Randazzo A, Rotili D, Mai A, Cappabianca S, Mashaghi A, Ciardiello F, Altucci L, Benedetti R. Histone lysine demethylase inhibition reprograms prostate cancer metabolism and mechanics. Mol Metab. 2022, 64:101561. doi: 10.1016/j.molmet.2022.101561.
12. Fiorentino F, Castiello C, Mai A, Rotili D. Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5. J Med Chem. 2022, 65(14):9580-9606. doi: 10.1021/acs.jmedchem.2c00687.
13. Di Bello E, Noce B, Fioravanti R, Zwergel C, Valente S, Rotili D, Fianco G, Trisciuoglio D, Mourão MM, Sales P Jr, Lamotte S, Prina E, Späth GF, Häberli C, Keiser J, Mai A. Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni. ACS Infect Dis. 2022, 8(7):1356-1366. doi: 10.1021/acsinfecdis.2c00232.
14. Cristalli C, Manara MC, Valente S, Pellegrini E, Bavelloni A, De Feo A, Blalock W, Di Bello E, Piñeyro D, Merkel A, Esteller M, Tirado OM, Mai A, Scotlandi K. Novel Targeting of DNA Methyltransferase Activity Inhibits Ewing Sarcoma Cell Proliferation and Enhances Tumor Cell Sensitivity to DNA Damaging Drugs by Activating the DNA Damage Response. Front Endocrinol (Lausanne). 2022, 13:876602. doi: 10.3389/fendo.2022.876602.
15. Fiorentino F, Mautone N, Menna M, D'Acunzo F, Mai A, Rotili D. Sirtuin modulators: past, present, and future perspectives. Future Med Chem. 2022, 14(12):915-939. doi: 10.4155/fmc-2022-0031.
16. Menna M, Fiorentino F, Marrocco B, Lucidi A, Tomassi S, Cilli D, Romanenghi M, Cassandri M, Pomella S, Pezzella M, Del Bufalo D, Zeya Ansari MS, Tomašević N, Mladenović M, Viviano M, Sbardella G, Rota R, Trisciuoglio D, Minucci S, Mattevi A, Rotili D, Mai A. Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models. Eur J Med Chem. 2022, 237:114410. doi: 10.1016/j.ejmech.2022.114410. PMID: 35525212.
17. Consalvi S, Tucciarone L, Macrì E, De Bardi M, Picozza M, Salvatori I, Renzini A, Valente S, Mai A, Moresi V, Puri PL. Determinants of epigenetic resistance to HDAC inhibitors in dystrophic fibro-adipogenic progenitors. EMBO Rep. 2022 Apr 4:e54721. doi: 10.15252/embr.202254721
18. Fioravanti R, Rodriguez V, Caroli J, Chianese U, Benedetti R, Di Bello E, Noce B, Zwergel C, Corinti D, Viña D, Altucci L, Mattevi A, Valente S, Mai A. Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity. J Enzyme Inhib Med Chem. 2022 Dec;37(1):973-985. doi: 10.1080/14756366.2022.2052869.
19. Valentini E, D'Aguanno S, Di Martile M, Montesano C, Ferraresi V, Patsilinakos A, Sabatino M, Antonini L, Chiacchiarini M, Valente S, Mai A, Colotti G, Ragno R, Trisciuoglio D, Del Bufalo D. Targeting the anti-apoptotic Bcl-2 family proteins: machine learning virtual screening and biological evaluation of new small molecules. Theranostics. 2022 Feb 28;12(5):2427-2444. doi: 10.7150/thno.64233.
20. Morroni J, Schirone L, Valenti V, Zwergel C, Riera CS, Valente S, Vecchio D, Schiavon S, Ragno R, Mai A, Sciarretta S, Lozanoska-Ochser B, Bouchè M. Inhibition of PKCθ Improves Dystrophic Heart Phenotype and Function in a Novel Model of DMD Cardiomyopathy. Int J Mol Sci. 2022 Feb 18;23(4):2256. doi: 10.3390/ijms23042256.
21. Siciliano G, Di Paolo V, Rotili D, Migale R, Pedini F, Casella M, Camerini S, Dalzoppo D, Henderson R, Huijs T, Dechering KJ, Mai A, Caccuri AM, Lalle M, Quintieri L, Alano P. The Nitrobenzoxadiazole Derivative NBDHEX Behaves as Plasmodium falciparum Gametocyte Selective Inhibitor with Malaria Parasite Transmission Blocking Activity. Pharmaceuticals (Basel). 2022 Jan 29;15(2):168. doi: 10.3390/ph15020168.
22. Renzini A, Marroncelli N, Cavioli G, Di Francescantonio S, Forcina L, Lambridis A, Di Giorgio E, Valente S, Mai A, Brancolini C, Giampietri C, Magenta A, De Santa F, Adamo S, Coletti D, Moresi V. Cytoplasmic HDAC4 regulates the membrane repair mechanism in Duchenne muscular dystrophy. J Cachexia Sarcopenia Muscle. 2022 Apr;13(2):1339-1359. doi: 10.1002/jcsm.12891.
23. Minisini M, Di Giorgio E, Kerschbamer E, Dalla E, Faggiani M, Franforte E, Meyer-Almes FJ, Ragno R, Antonini L, Mai A, Fiorentino F, Rotili D, Chinellato M, Perin S, Cendron L, Weichenberger CX, Angelini A, Brancolini C. Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription. Nucleic Acids Res. 2022 Mar 21;50(5):2566-2586. doi: 10.1093/nar/gkac081.
24. Mouveaux T, Rotili D, Boissavy T, Roger E, Pierrot C, Mai A, Gissot M. A potent HDAC inhibitor blocks Toxoplasma gondii tachyzoite growth and profoundly disrupts parasite gene expression. Int J Antimicrob Agents. 2022 Mar;59(3):106526. doi: 10.1016/j.ijantimicag.2022.106526.
25. Nowak RP, Tumber A, Hendrix E, Ansari MSZ, Sabatino M, Antonini L, Andrijes R, Salah E, Mautone N, Pellegrini FR, Simelis K, Kawamura A, Johansson C, Passeri D, Pellicciari R, Ciogli A, Del Bufalo D, Ragno R, Coleman ML, Trisciuoglio D, Mai A, Oppermann U, Schofield CJ, Rotili D. First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53. J Med Chem. 2021 Dec 9;64(23):17031-17050. doi: 10.1021/acs.jmedchem.1c00605.
26. Fiorentino F, Rotili D, Mai A, Bolla JR, Robinson CV. Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein-protein interactions. Chem Commun (Camb). 2021 Oct 14;57(82):10747-10750. doi: 10.1039/d1cc04186j.
27. Fiorentino F, De Angelis M, Menna M, Rovere A, Caccuri AM, D'Acunzo F, Palamara AT, Nencioni L, Rotili D, Mai A. Anti-influenza A virus activity and structure-activity relationship of a series of nitrobenzoxadiazole derivatives. J Enzyme Inhib Med Chem. 2021 Dec;36(1):2128-2138. doi: 10.1080/14756366.2021.1982932.
28. Tomassi S, Romanelli A, Zwergel C, Valente S, Mai A. Polycomb Repressive Complex 2 Modulation through the Development of EZH2-EED Interaction Inhibitors and EED Binders. J Med Chem. 2021 Aug 26;64(16):11774-11797. doi: 10.1021/acs.jmedchem.1c00226.
29. Mormino A, Cocozza G, Fontemaggi G, Valente S, Esposito V, Santoro A, Bernardini G, Santoni A, Fazi F, Mai A, Limatola C, Garofalo S. Histone-deacetylase 8 drives the immune response and the growth of glioma. Glia. 2021 Nov;69(11):2682-2698. doi: 10.1002/glia.24065.
30. Hu T, Shukla SK, Vernucci E, He C, Wang D, King RJ, Jha K, Siddhanta K, Mullen NJ, Attri KS, Murthy D, Chaika NV, Thakur R, Mulder SE, Pacheco CG, Fu X, High RR, Yu F, Lazenby A, Steegborn C, Lan P, Mehla K, Rotili D, Chaudhary S, Valente S, Tafani M, Mai A, Auwerx J, Verdin E, Tuveson D, Singh PK. Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression. Gastroenterology. 2021 Nov;161(5):1584-1600. doi: 10.1053/j.gastro.2021.06.045.
31. Fiorentino F, Mai A, Rotili D. Emerging Therapeutic Potential of SIRT6 Modulators. J Med Chem. 2021 Jul 22;64(14):9732-9758. doi: 10.1021/acs.jmedchem.1c00601.
32. Molinari F, Feraco A, Mirabilii S, Saladini S, Sansone L, Vernucci E, Tomaselli G, Marzolla V, Rotili D, Russo MA, Ricciardi MR, Tafuri A, Mai A, Caprio M, Tafani M, Armani A. SIRT5 Inhibition Induces Brown Fat-Like Phenotype in 3T3-L1 Preadipocytes. Cells. 2021 May 7;10(5):1126. doi: 10.3390/cells10051126.
33. Fiorentino F, Carafa V, Favale G, Altucci L, Mai A, Rotili D. The Two-Faced Role of SIRT6 in Cancer. Cancers (Basel). 2021 Mar 8;13(5):1156. doi: 10.3390/cancers13051156.
34. Benedetti R, Papulino C, Sgueglia G, Chianese U, De Marchi T, Iovino F, Rotili D, Mai A, Niméus E, Dell' Aversana C, Altucci L. Regulatory Interplay between miR-181a-5p and Estrogen Receptor Signaling Cascade in Breast Cancer. Cancers (Basel). 2021 Feb 1;13(3):543. doi: 10.3390/cancers13030543.
35. Zwergel C, Di Bello E, Fioravanti R, Conte M, Nebbioso A, Mazzone R, Brosch G, Mercurio C, Varasi M, Altucci L, Valente S, Mai A. Novel Pyridine-Based Hydroxamates and 2'-Aminoanilides as Histone Deacetylase Inhibitors: Biochemical Profile and Anticancer Activity. ChemMedChem. 2021 Mar 18;16(6):989-999. doi: 10.1002/cmdc.202000854.

Research products

11573/1714682 - 2024 - Pharmacological activation of SIRT3 modulates the response of cancer cells to acidic ph
Aventaggiato, Michele; Arcangeli, Tania; Vernucci, Enza; Barreca, Federica; Sansone, Luigi; Pellegrini, Laura; Pontemezzo, Elena; Valente, Sergio; Fioravanti, Rossella; Antonio Russo, Matteo; Mai, Antonello; Tafani, Marco - 01a Articolo in rivista
paper: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. - - issn: 1424-8247 - wos: WOS:001256759700001 (0) - scopus: 2-s2.0-85197858664 (0)

11573/1717112 - 2024 - HDAC3 genetic and pharmacologic inhibition radiosensitizes fusion positive rhabdomyosarcoma by promoting DNA double-strand breaks
Cassandri, Matteo; Porrazzo, Antonella; Pomella, Silvia; Noce, Beatrice; Zwergel, Clemens; Aiello, Francesca Antonella; Vulcano, Francesca; Milazzo, Luisa; Camero, Simona; Pajalunga, Deborah; Spada, Massimo; Manzi, Valeria; Gravina, Giovanni Luca; Codenotti, Silvia; Piccione, Michela; Tomaciello, Miriam; Signore, Michele; Barillari, Giovanni; Marchese, Cinzia; Fanzani, Alessandro; De Angelis, Biagio; Quintarelli, Concetta; Vakoc, Christopher R.; Chen, Eleanor Y.; Megiorni, Francesca; Locatelli, Franco; Valente, Sergio; Mai, Antonello; Rota, Rossella; Marampon, Francesco - 01a Articolo in rivista
paper: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. - - issn: 2058-7716 - wos: WOS:001284933200001 (0) - scopus: 2-s2.0-85200542198 (1)

11573/1696800 - 2024 - Enhancing sensitivity of triple-negative breast cancer to DNA-damaging therapy through chemical inhibition of the m6A methyltransferase METTL3
Cesaro, Bianca; Iaiza, Alessia; Piscopo, Fabio; Tarullo, Marco; Cesari, Eleonora; Rotili, Dante; Mai, Antonello; Diana, Alberto; Londero, Michela; Del Giacco, Luca; Masetti, Riccardo; Di Leone, Alba; Naro, Chiara; Masciarelli, Silvia; Fontemaggi, Giulia; Sette, Claudio; Fazi, Francesco; Fatica, Alessandro - 01f Lettera, Nota
paper: CANCER COMMUNICATIONS (London: BioMed Central) pp. 282-286 - issn: 2523-3548 - wos: WOS:001125441200001 (5) - scopus: 2-s2.0-85179653539 (7)

11573/1729425 - 2024 - Activation and inhibition of sirtuins: From bench to bedside
Fiorentino, Francesco; Fabbrizi, Emanuele; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
paper: MEDICINAL RESEARCH REVIEWS ([New York, N.Y.] : Wiley) pp. - - issn: 1098-1128 - wos: WOS:001303039100001 (1) - scopus: 2-s2.0-85202827159 (1)

11573/1710159 - 2024 - Uracil- and Pyridine-containing HDAC inhibitors displayed cytotoxicity in colorectal and glioblastoma cancer stem cells
Fiorentino, Francesco; Fabbrizi, Emanuele; Raucci, Alessia; Noce, Beatrice; Fioravanti, Rossella; Valente, Sergio; Paolini, Chantal; De Maria, Ruggero; Steinkühler, Christian; Gallinari, Paola; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. - - issn: 1860-7187 - wos: WOS:001214621100001 (1) - scopus: 2-s2.0-85191719139 (1)

11573/1712838 - 2024 - m6A modification inhibits miRNAs’ intracellular function, favoring their extracellular export for intercellular communication
Garbo, S.; D'andrea, D.; Colantoni, A.; Fiorentino, F.; Mai, A.; Ramos, A.; Tartaglia, G. G.; Tancredi, A.; Tripodi, M.; Battistelli, C. - 01a Articolo in rivista
paper: CELL REPORTS (Elsevier B.V. Cambridge MA: Cell Press) pp. - - issn: 2211-1247 - wos: WOS:001255604000001 (0) - scopus: 2-s2.0-85195878545 (2)

11573/1701222 - 2024 - SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process
Lambona, Chiara; Zwergel, Clemens; Valente, Sergio; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1662-1689 - issn: 0022-2623 - wos: WOS:001160599300001 (13) - scopus: 2-s2.0-85183983381 (12)

11573/1710803 - 2024 - A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection
Maure, Alexandra; Lawarée, Emeline; Fiorentino, Francesco; Pawlik, Alexandre; Gona, Saideep; Giraud-Gatineau, Alexandre; Eldridge, Matthew J. G.; Danckaert, Anne; Hardy, David; Frigui, Wafa; Keck, Camille; Gutierrez, Claude; Neyrolles, Olivier; Aulner, Nathalie; Mai, Antonello; Hamon, Mélanie; Barreiro, Luis B.; Brodin, Priscille; Brosch, Roland; Rotili, Dante; Tailleux, Ludovic - 01a Articolo in rivista
paper: PLOS BIOLOGY (San Francisco, CA : Public Library of Science, c2003-) pp. - - issn: 1545-7885 - wos: WOS:001214097100008 (1) - scopus: 2-s2.0-85191815044 (0)

11573/1703580 - 2024 - Specific inhibitors of mitochondrial deacylase sirtuin 4 endowed with cellular activity
Pannek, M.; Alhalabi, Z.; Tomaselli, D.; Menna, M.; Fiorentino, F.; Robaa, D.; Weyand, M.; Puhlmann, M.; Tomassi, S.; Barreca, F.; Tafani, M.; Zaganjor, E.; Haigis, M. C.; Sippl, W.; Rotili, D.; Mai, A.; Steegborn, C. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 1843-1860 - issn: 1520-4804 - wos: WOS:001160605300001 (4) - scopus: 2-s2.0-85184667987 (4)

11573/1703586 - 2024 - Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer
Pecci, Valeria; Troisi, Fabiola; Aiello, Aurora; De Martino, Sara; Carlino, Angela; Fiorentino, Vincenzo; Ripoli, Cristian; Rotili, Dante; Pierconti, Francesco; Martini, Maurizio; Porru, Manuela; Pinto, Francesco; Mai, Antonello; Bassi, Pier Francesco; Grassi, Claudio; Gaetano, Carlo; Pontecorvi, Alfredo; Strigari, Lidia; Farsetti, Antonella; Nanni, Simona - 01a Articolo in rivista
paper: CANCER CELL INTERNATIONAL ([London]: BioMed Central.) pp. - - issn: 1475-2867 - wos: WOS:001156914300001 (1) - scopus: 2-s2.0-85184414355 (4)

11573/1710160 - 2024 - Heterocycles-containing HDAC inhibitors active in cancer. An overview of the last fifteen years
Raucci, Alessia; Castiello, Carola; Mai, Antonello; Zwergel, Clemens; Valente, Sergio - 01g Articolo di rassegna (Review)
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1-53 - issn: 1860-7179 - wos: WOS:001300014900001 (2) - scopus: 2-s2.0-85202594031 (3)

11573/1714195 - 2024 - Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1
Spizzichino, Sharon; Di Fonzo, Federica; Marabelli, Chiara; Tramonti, Angela; Chaves-Sanjuan, Antonio; Parroni, Alessia; Boumis, Giovanna; Liberati, Francesca Romana; Paone, Alessio; Montemiglio, Linda Celeste; Ardini, Matteo; Jakobi, Arjen J.; Bharadwaj, Alok; Swuec, Paolo; Tartaglia, Gian Gaetano; Paiardini, Alessandro; Contestabile, Roberto; Mai, Antonello; Rotili, Dante; Fiorentino, Francesco; Macone, Alberto; Giorgi, Alessandra; Tria, Giancarlo; Rinaldo, Serena; Bolognesi, Martino; Giardina, Giorgio; Cutruzzola, Francesca - 01a Articolo in rivista
paper: MOLECULAR CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 2682-2697 - issn: 1097-2765 - wos: WOS:001281962900001 (0) - scopus: 2-s2.0-85198588581 (1)

11573/1729153 - 2024 - Off-target inhibition of human dihydroorotate dehydrogenase (hDHODH) highlights challenges in the development of fat mass and obesity-associated protein (FTO) inhibitors
Tarullo, M.; Fernandez Rodriguez, G.; Iaiza, A.; Venezia, S.; Macone, A.; Incocciati, A.; Masciarelli, S.; Marchioni, M.; Giorgis, M.; Lolli, M. L.; Fornaseri, F.; Proietti, L.; Grebien, F.; Rosignoli, S.; Paiardini, A.; Rotili, D.; Mai, A.; Bochenkova, E.; Caflisch, A.; Fazi, F.; Fatica, A. - 01a Articolo in rivista
paper: ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (Washington DC: American Chemical Society) pp. - - issn: 2575-9108 - wos: WOS:001366197700001 (0) - scopus: 2-s2.0-85210408199 (0)

11573/1700487 - 2024 - HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling
Terri, Michela; Sandoval, Pilar; Bontempi, Giulio; Montaldo, Claudia; Tomero-Sanz, Henar; De Turris, Valeria; Trionfetti, Flavia; Pascual-Antón, Lucía; Clares-Pedrero, Irene; Battistelli, Cecilia; Valente, Sergio; Zwergel, Clemens; Mai, Antonello; Rosanò, Laura; Del Pozo, Miguel Ángel; Sánchez-Álvarez, Miguel; Cabañas, Carlos; Tripodi, Marco; López-Cabrera, Manuel; Strippoli, Raffaele - 01a Articolo in rivista
paper: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. - - issn: 1756-9966 - wos: WOS:001147742000001 (2) - scopus: 2-s2.0-85182865073 (2)

11573/1702828 - 2024 - Mechanisms of mesothelial cell response to viral infections: HDAC1-3 inhibition blocks poly(I:C)-induced type I interferon response and modulates the mesenchymal/inflammatory phenotype
Trionfetti, Flavia; Montaldo, Claudia; Caiello, Ivan; Bontempi, Giulio; Terri, Michela; Tiberi, Marta; Marchant, Vanessa; Domenici, Alessandro; Menè, Paolo; Cordani, Marco; Zwergel, Clemens; Prencipe, Giusi; Ruiz-Ortega, Marta; Valente, Sergio; Mai, Antonello; Tripodi, Marco; Strippoli, Raffaele - 01a Articolo in rivista
paper: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (Lausanne : Frontiers Media SA, 2011-) pp. - - issn: 2235-2988 - wos: WOS:001180097600001 (2) - scopus: 2-s2.0-85187169859 (1)

11573/1705172 - 2024 - Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy
Villares, Marie; Lourenço, Nelly; Ktorza, Ivan; Berthelet, Jérémy; Panagiotou, Aristeidis; Richard, Aurélie; Amo, Angélique; Koziy, Yulianna; Medjkane, Souhila; Valente, Sergio; Fioravanti, Rossella; Pioche-Durieu, Catherine; Lignière, Laurent; Chevreux, Guillaume; Mai, Antonello; Weitzman, Jonathan B. - 01a Articolo in rivista
paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. 1-14 - issn: 2041-1723 - wos: WOS:001185523200018 (1) - scopus: 2-s2.0-85187493170 (1)

11573/1729427 - 2024 - Successes and challenges in the development of BD1-selective BET inhibitors: a patent review
Viviano, Monica; Cipriano, Alessandra; Fabbrizi, Emanuele; Feoli, Alessandra; Castellano, Sabrina; Sbardella, Gianluca; Mai, Antonello; Milite, Ciro; Rotili, Dante - 01g Articolo di rassegna (Review)
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 529-545 - issn: 1354-3776 - wos: (0) - scopus: (0)

11573/1661959 - 2023 - Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells
Ansari, Mohammad Salik Zeya; Stagni, Venturina; Iuzzolino, Angela; Rotili, Dante; Mai, Antonello; Del Bufalo, Donatella; Lavia, Patrizia; Degrassi, Francesca; Trisciuoglio, Daniela - 01a Articolo in rivista
paper: CANCER GENE THERAPY (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 124-136 - issn: 0929-1903 - wos: WOS:000854955000001 (11) - scopus: 2-s2.0-85138300847 (12)

11573/1673946 - 2023 - Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery
Aventaggiato, Michele; Barreca, Federica; Vitiello, Laura; Vespa, Simone; Valente, Sergio; Rotili, Dante; Mai, Antonello; Lotti, Lavinia Vittoria; Sansone, Luigi; Russo, Matteo A.; Bizzarri, Mariano; Ferretti, Elisabetta; Tafani, Marco - 01a Articolo in rivista
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000947513100001 (2) - scopus: 2-s2.0-85149752388 (4)

11573/1687782 - 2023 - SIRT5 Activation and Inorganic Phosphate Binding Reduce Cancer Cell Vitality by Modulating Autophagy/Mitophagy and ROS
Barreca, Federica; Aventaggiato, Michele; Vitiello, Laura; Sansone, Luigi; Russo, Matteo Antonio; Mai, Antonello; Valente, Sergio; Tafani, Marco - 01a Articolo in rivista
paper: ANTIOXIDANTS (Basel: MDPI) pp. 1635- - issn: 2076-3921 - wos: WOS:001119091200001 (6) - scopus: 2-s2.0-85169132437 (7)

11573/1694442 - 2023 - Hydroxamate-based compounds are potent inhibitors of Toxoplasma gondii HDAC biological activity
Boissavy, Tom; Rotili, Dante; Mouveaux, Thomas; Roger, Emmanuel; Aliouat, El Moukthar; Pierrot, Christine; Valente, Sergio; Mai, Antonello; Gissot, Mathieu - 01a Articolo in rivista
paper: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (American Society for Microbiology:PO Box 11127:Birmingham, AL 35201:(800)633-4931, (205)995-1567, EMAIL: asm.nonmembers.subs@ebsco.com, INTERNET: http://www.asm.org, Fax: (205)995-1588) pp. e0066123- - issn: 0066-4804 - wos: WOS:001090003100001 (2) - scopus: (0)

11573/1674091 - 2023 - GreenMedChem. The challenge in the next decade toward eco-friendly compounds and processes in drug design
Castiello, Carola; Junghanns, Pierre; Mergel, Annika; Jacob, Claus; Ducho, Christian; Valente, Sergio; Rotili, Dante; Fioravanti, Rossella; Zwergel, Clemens; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: GREEN CHEMISTRY (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 2109-2169 - issn: 1463-9262 - wos: WOS:000946579600001 (42) - scopus: 2-s2.0-85150432512 (49)

11573/1662777 - 2023 - Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells
Di Bello, Elisabetta; Sian, Veronica; Bontempi, Giulio; Zwergel, Clemens; Fioravanti, Rossella; Noce, Beatrice; Castiello, Carola; Tomassi, Stefano; Corinti, Davide; Passeri, Daniela; Pellicciari, Roberto; Mercurio, Ciro; Varasi, Mario; Altucci, Lucia; Tripodi, Marco; Strippoli, Raffaele; Nebbioso, Angela; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 1-18 - issn: 0223-5234 - wos: WOS:000911596400001 (9) - scopus: 2-s2.0-85144323384 (9)

11573/1677023 - 2023 - Emerging roles of SIRT5 in metabolism, cancer, and SARS-CoV-2 infection
Fabbrizi, Emanuele; Fiorentino, Francesco; Carafa, Vincenzo; Altucci, Lucia; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 1-35 - issn: 2073-4409 - wos: WOS:000957394600001 (26) - scopus: 2-s2.0-85151108488 (28)

11573/1694364 - 2023 - State of the art of carbonic anhydrase activators
Fiorentino, Francesco; Carta, Fabrizio; Rotili, Dante; Mai, Antonello; Supuran, Claudiu T - 01m Editorial/Introduzione in rivista
paper: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 2025-2028 - issn: 1756-8919 - wos: WOS:001081530900001 (3) - scopus: 2-s2.0-85177103741 (3)

11573/1689870 - 2023 - The role of structural biology in the design of sirtuin activators
Fiorentino, Francesco; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
paper: CURRENT OPINION IN STRUCTURAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 102666- - issn: 0959-440X - wos: WOS:001057837700001 (5) - scopus: 2-s2.0-85169440750 (5)

11573/1669899 - 2023 - METTL3 from target validation to the first small-molecule inhibitors. A medicinal chemistry journey
Fiorentino, Francesco; Menna, Martina; Rotili, Dante; Valente, Sergio; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 1654-1677 - issn: 1520-4804 - wos: WOS:000932489700001 (34) - scopus: 2-s2.0-85147012551 (40)

11573/1677022 - 2023 - Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII
Fiorentino, Francesco; Nocentini, Alessio; Rotili, Dante; Supuran, Claudiu T; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 1-9 - issn: 1475-6366 - wos: WOS:000949495200001 (4) - scopus: 2-s2.0-85150225921 (4)

11573/1677024 - 2023 - Native mass spectrometry-directed drug discovery. Recent advances in investigating protein function and modulation
Fiorentino, Francesco; Rotili, Dante; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: DRUG DISCOVERY TODAY (Elsevier Science Limited Trends Journals:PO Box 331, Haywards Heath RH16 3FG United Kingdom:011 44 1444 475651, EMAIL: ct.subs@rbi.co.uk, Fax: 011 44 1444 445423) pp. 1-14 - issn: 1359-6446 - wos: WOS:000955583400001 (9) - scopus: 2-s2.0-85150033652 (10)

11573/1681512 - 2023 - First-in-class selective inhibitors of the lysine acetyltransferase KAT8
Fiorentino, Francesco; Sementilli, Sara; Menna, Martina; Turrisi, Federica; Tomassi, Stefano; Pellegrini, Francesca Romana; Iuzzolino, Angela; D'acunzo, Francesca; Feoli, Alessandra; Wapenaar, Hannah; Taraglio, Sophie; Fraschetti, Caterina; Del Bufalo, Donatella; Sbardella, Gianluca; Dekker, Frank J.; Paiardini, Alessandro; Trisciuoglio, Daniela; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 6591-6616 - issn: 1520-4804 - wos: WOS:000988858800001 (6) - scopus: 2-s2.0-85159627845 (6)

11573/1685964 - 2023 - Histone deacetylase 10: A polyamine deacetylase from the crystal structure to the first inhibitors
Lambona, Chiara; Zwergel, Clemens; Fioravanti, Rossella; Valente, Sergio; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: CURRENT OPINION IN STRUCTURAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 1-9 - issn: 0959-440X - wos: (0) - scopus: 2-s2.0-85166517965 (5)

11573/1695097 - 2023 - BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress
Marchant, Vanessa; Trionfetti, Flavia; Tejedor-Santamaria, Lucia; Rayego-Mateos, Sandra; Rotili, Dante; Bontempi, Giulio; Domenici, Alessandro; Menè, Paolo; Mai, Antonello; Martín-Cleary, Catalina; Ortiz, Alberto; Ramos, Adrian M.; Strippoli, Raffaele; Ruiz-Ortega, Marta - 01a Articolo in rivista
paper: ANTIOXIDANTS (Basel: MDPI) pp. 1-19 - issn: 2076-3921 - wos: WOS:001137851500001 (0) - scopus: 2-s2.0-85180466019 (0)

11573/1669922 - 2023 - Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells
Negri, Aide; Marozzi, Marina; Trisciuoglio, Daniela; Rotili, Dante; Mai, Antonello; Rizzi, Federica - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Abingdon Oxfordshire United Kingdom: Taylor & Francis London: Gordon and Breach, 2002-) pp. 1-12 - issn: 1475-6374 - wos: WOS:000911853100001 (5) - scopus: 2-s2.0-85146193316 (8)

11573/1670227 - 2023 - LSD1 inhibitors for cancer treatment: Focus on multi-target agents and compounds in clinical trials
Noce, Beatrice; Di Bello, Elisabetta; Fioravanti, Rossella; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000935304500001 (32) - scopus: 2-s2.0-85148335525 (53)

11573/1658358 - 2023 - Chemically diverse S. mansoni HDAC8 inhibitors reduced viability in worm larval and adult stages
Noce, Beatrice; Di Bello, Elisabetta; Zwergel, Clemens; Fioravanti, Rossella; Valente, Sergio; Rotili, Dante; Masotti, Andrea; Ansari, Mohammad Salik Zeya; Trisciuoglio, Daniela; Chakrabarti, Alokta; Romier, Christophe; Robaa, Dina; Sippl, Wolfgang; Jung, Manfred; Häberli, Cécile; Keiser, Jennifer; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. - - issn: 1860-7179 - wos: WOS:000879912800001 (7) - scopus: 2-s2.0-85141693563 (7)

11573/1691312 - 2023 - Targeting ROS production through inhibition of NADPH oxidases
Reis, Joana; Gorgulla, Christoph; Massari, Marta; Marchese, Sara; Valente, Sergio; Noce, Beatrice; Basile, Lorenzo; Törner, Ricarda; Cox, Huel; Viennet, Thibault; Yang, Moon Hee; Ronan, Melissa M; Rees, Matthew G; Roth, Jennifer A; Capasso, Lucia; Nebbioso, Angela; Altucci, Lucia; Mai, Antonello; Arthanari, Haribabu; Mattevi, Andrea - 01a Articolo in rivista
paper: NATURE CHEMICAL BIOLOGY (New York, N.Y. : Nature Pub. Group, 2005-) pp. 1540-1550 - issn: 1552-4469 - wos: WOS:001090044900002 (9) - scopus: 2-s2.0-85174921719 (16)

11573/1689849 - 2023 - Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa.
Scribani Rossi, C; Eckartt, K; Scarchilli, E; Angeli, S; Price-Whelan, A; Di Matteo, A; Chevreuil, M; Raynal, B; Arcovito, A; Giacon, N; Fiorentino, F; Rotili, D; Mai, A; Espinosa-Urgel, M; Cutruzzola', F; Dietrich, Lep; Paone, A; Paiardini, A; Rinaldo, S - 01a Articolo in rivista
paper: MICROBIOLOGICAL RESEARCH (Urban & Fischer Verlag Jena:Postfach 100537, D-07705 Jena Germany:011 49 3641 626430, EMAIL: journals@urbanfischer.de, INTERNET: http://www.urbanfischer.de, Fax: 011 49 3641 626500) pp. 127498- - issn: 0944-5013 - wos: WOS:001097478000001 (6) - scopus: 2-s2.0-85173505521 (6)

11573/1696065 - 2023 - HDAC1-3 inhibition increases SARS-CoV-2 replication and productive infection in lung mesothelial and epithelial cells
Trionfetti, Flavia; Alonzi, Tonino; Bontempi, Giulio; Terri, Michela; Battistelli, Cecilia; Montaldo, Claudia; Repele, Federica; Rotili, Dante; Valente, Sergio; Zwergel, Clemens; Matusali, Giulia; Maggi, Fabrizio; Goletti, Delia; Tripodi, Marco; Mai, Antonello; Strippoli, Raffaele - 01a Articolo in rivista
paper: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (Lausanne : Frontiers Media SA, 2011-) pp. - - issn: 2235-2988 - wos: WOS:001130489700001 (4) - scopus: 2-s2.0-85180885673 (5)

11573/1694558 - 2023 - SIRT6 Protects Against Lipopolysaccharide-Induced Inflammation in Human Pulmonary Lung Microvascular Endothelial Cells
Wang, Jinping; Luo, Jinque; Rotili, Dante; Mai, Antonello; Steegborn, Clemens; Xu, Suowen; Jin, Zheng Gen - 01a Articolo in rivista
paper: INFLAMMATION (Springer Nature New York, NY: Plenum Press) pp. - - issn: 0360-3997 - wos: WOS:001082492200001 (5) - scopus: 2-s2.0-85173797364 (5)

11573/1694680 - 2023 - Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase
Zhou, Jujun; Deng, Youchao; Iyamu, Iredia D; Horton, John R; Yu, Dan; Hajian, Taraneh; Vedadi, Masoud; Rotili, Dante; Mai, Antonello; Blumenthal, Robert M; Zhang, Xing; Huang, Rong; Cheng, Xiaodong - 01a Articolo in rivista
paper: ACS CHEMICAL BIOLOGY (Washington, D.C. : American Chemical Society, c2006-) pp. 734-745 - issn: 1554-8937 - wos: WOS:000936764500001 (3) - scopus: 2-s2.0-85148863880 (3)

11573/1664753 - 2023 - Systematic design of adenosine analogs as inhibitors of a clostridioides difficile-specific DNA adenine methyltransferase required for normal sporulation and persistence
Zhou, Jujun; Horton, John R.; Menna, Martina; Fiorentino, Francesco; Ren, Ren; Yu, Dan; Hajian, Taraneh; Vedadi, Masoud; Mazzoccanti, Giulia; Ciogli, Alessia; Weinhold, Elmar; Hüben, Michael; Blumenthal, Robert M.; Zhang, Xing; Mai, Antonello; Rotili, Dante; Cheng, Xiaodong - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 934-950 - issn: 0022-2623 - wos: WOS:000907749800001 (5) - scopus: 2-s2.0-85145455635 (5)

11573/1684985 - 2023 - Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells
Zwergel, Clemens; Aventaggiato, Michele; Garbo, Sabrina; Di Bello, Elisabetta; Fassari, Bruno; Noce, Beatrice; Castiello, Carola; Lambona, Chiara; Barreca, Federica; Rotili, Dante; Fioravanti, Rossella; Schmalz, Thomas; Weyand, Michael; Niedermeier, Amelie; Tripodi, Marco; Colotti, Gianni; Steegborn, Clemens; Battistelli, Cecilia; Tafani, Marco; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9622-9641 - issn: 0022-2623 - wos: WOS:001027732800001 (9) - scopus: 2-s2.0-85165671509 (10)

11573/1659805 - 2023 - PD-L1 small-molecule modulators: a new hope in epigenetic-based multidrug cancer therapy?
Zwergel, Clemens; Fioravanti, Rossella; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: DRUG DISCOVERY TODAY (Elsevier Science Limited Trends Journals:PO Box 331, Haywards Heath RH16 3FG United Kingdom:011 44 1444 475651, EMAIL: ct.subs@rbi.co.uk, Fax: 011 44 1444 445423) pp. - - issn: 1359-6446 - wos: WOS:000917237100004 (13) - scopus: 2-s2.0-85141980634 (12)

11573/1659806 - 2022 - Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells
Bontempi, Giulio; Terri, Michela; Garbo, Sabrina; Montaldo, Claudia; Mariotti, Davide; Bordoni, Veronica; Valente, Sergio; Zwergel, Clemens; Mai, Antonello; Marchetti, Alessandra; Domenici, Alessandro; Menè, Paolo; Battistelli, Cecilia; Tripodi, Marco; Strippoli, Raffaele - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. 965- - issn: 2041-4889 - wos: WOS:000885083500004 (15) - scopus: 2-s2.0-85142134241 (13)

11573/1658360 - 2022 - Histone lysine demethylase inhibition reprograms prostate cancer metabolism and mechanics
Chianese, Ugo; Papulino, Chiara; Passaro, Eugenia; Evers, Tom Mj; Babaei, Mehrad; Toraldo, Antonella; De Marchi, Tommaso; Niméus, Emma; Carafa, Vincenzo; Nicoletti, Maria Maddalena; Del Gaudio, Nunzio; Iaccarino, Nunzia; Randazzo, Antonio; Rotili, Dante; Mai, Antonello; Cappabianca, Salvatore; Mashaghi, Alireza; Ciardiello, Fortunato; Altucci, Lucia; Benedetti, Rosaria - 01a Articolo in rivista
paper: MOLECULAR METABOLISM (Amsterdam : Elsevier) pp. 101561- - issn: 2212-8778 - wos: WOS:000844094200002 (5) - scopus: 2-s2.0-85136069603 (5)

11573/1643002 - 2022 - Determinants of epigenetic resistance to HDAC inhibitors in dystrophic fibro-adipogenic progenitors
Consalvi, S.; Tucciarone, L.; Macri, E.; De Bardi, M.; Picozza, M.; Salvatori, I.; Renzini, A.; Valente, S.; Mai, A.; Moresi, V.; Puri, P. L. - 01a Articolo in rivista
paper: EMBO REPORTS (Oxford : Oxford University Press, 2000-) pp. 1-19 - issn: 1469-221X - wos: WOS:000778177100001 (10) - scopus: 2-s2.0-85127391022 (10)

11573/1705179 - 2022 - Novel Targeting of DNA Methyltransferase Activity Inhibits Ewing Sarcoma Cell Proliferation and Enhances Tumor Cell Sensitivity to DNA Damaging Drugs by Activating the DNA Damage Response
Cristalli, C.; Manara, M. C.; Valente, S.; Pellegrini, E.; Bavelloni, A.; De Feo, A.; Blalock, W.; Di Bello, E.; Pineyro, D.; Merkel, A.; Esteller, M.; Tirado, O. M.; Mai, A.; Scotlandi, K. - 01a Articolo in rivista
paper: FRONTIERS IN ENDOCRINOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-2392 - wos: WOS:000811105900001 (9) - scopus: 2-s2.0-85132379050 (8)

11573/1644085 - 2022 - Current HDAC inhibitors in clinical trials
Di Bello, Elisabetta; Noce, Beatrice; Fioravanti, Rossella; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: CHIMIA (Swiss Chemical Society:Barenplatz 2, CH 3011 Bern Switzerland:011 41 31 3104090, EMAIL: info@swiss-chem-soc.ch, markus.straub@swiss-chem-soc.ch, INTERNET: http://www.swiss-chem-soc.ch, Fax: 011 41 31 3121678) pp. 1-6 - issn: 0009-4293 - wos: WOS:000929447400008 (12) - scopus: 2-s2.0-85132577121 (15)

11573/1650772 - 2022 - Effects of structurally different HDAC inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni
Di Bello, Elisabetta; Noce, Beatrice; Fioravanti, Rossella; Zwergel, Clemens; Valente, Sergio; Rotili, Dante; Fianco, Giulia; Trisciuoglio, Daniela; Mourão, Marina M; Sales, Policarpo; Lamotte, Suzanne; Prina, Eric; Späth, Gerald F; Häberli, Cécile; Keiser, Jennifer; Mai, Antonello - 01a Articolo in rivista
paper: ACS INFECTIOUS DISEASES (Washington, DC : American Chemical Society, 2015-) pp. 1356-1366 - issn: 2373-8227 - wos: WOS:000819851400001 (16) - scopus: 2-s2.0-85134360722 (17)

11573/1623778 - 2022 - Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity
Fioravanti, Rossella; Rodriguez, Veronica; Caroli, Jonatan; Chianese, Ugo; Benedetti, Rosaria; Di Bello, Elisabetta; Noce, Beatrice; Zwergel, Clemens; Corinti, Davide; Viña, Dolores; Altucci, Lucia; Mattevi, Andrea; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 973-985 - issn: 1475-6366 - wos: WOS:000771778600001 (1) - scopus: 2-s2.0-85126852334 (1)

11573/1657352 - 2022 - Therapeutic potential and activity modulation of the protein lysine deacylase sirtuin 5
Fiorentino, F.; Castiello, C.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9580-9606 - issn: 0022-2623 - wos: WOS:000835071900001 (20) - scopus: 2-s2.0-85135378527 (29)

11573/1638052 - 2022 - Sirtuin modulators: past, present, and future perspectives
Fiorentino, Francesco; Mautone, Nicola; Menna, Martina; D'acunzo, Francesca; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
paper: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. - - issn: 1756-8919 - wos: WOS:000797024400001 (0) - scopus: 2-s2.0-85131771683 (20)

11573/1635728 - 2022 - Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models
Menna, M.; Fiorentino, F.; Marrocco, B.; Lucidi, A.; Tomassi, S.; Cilli, D.; Romanenghi, M.; Cassandri, M.; Pomella, S.; Pezzella, M.; Del Bufalo, D.; Zeya Ansari, M. S.; Tomasevic, N.; Mladenovic, M.; Viviano, M.; Sbardella, G.; Rota, R.; Trisciuoglio, D.; Minucci, S.; Mattevi, A.; Rotili, D.; Mai, A. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000804176200002 (18) - scopus: 2-s2.0-85129352278 (18)

11573/1613297 - 2022 - Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription
Minisini, Martina; Di Giorgio, Eros; Kerschbamer, Emanuela; Dalla, Emiliano; Faggiani, Massimo; Franforte, Elisa; Meyer-Almes, Franz-Josef; Ragno, Rino; Antonini, Lorenzo; Mai, Antonello; Fiorentino, Francesco; Rotili, Dante; Chinellato, Monica; Perin, Stefano; Cendron, Laura; Weichenberger, Christian X; Angelini, Alessandro; Brancolini, Claudio - 01a Articolo in rivista
paper: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. - - issn: 0305-1048 - wos: WOS:000764227300001 (15) - scopus: 2-s2.0-85127539205 (15)

11573/1612791 - 2022 - Inhibition of PKCθ Improves Dystrophic Heart Phenotype and Function in a Novel Model of DMD Cardiomyopathy
Morroni, Jacopo; Schirone, Leonardo; Valenti, Valentina; Zwergel, Clemens; Riera, Carles Sánchez; Valente, Sergio; Vecchio, Daniele; Schiavon, Sonia; Ragno, Rino; Mai, Antonello; Sciarretta, Sebastiano; Lozanoska-Ochser, Biliana; Bouchè, Marina - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-16 - issn: 1422-0067 - wos: WOS:000772462700001 (1) - scopus: 2-s2.0-85124895071 (1)

11573/1622839 - 2022 - A potent HDAC inhibitor blocks Toxoplasma gondii tachyzoite growth and profoundly disrupts parasite gene expression
Mouveaux, T.; Rotili, D.; Boissavy, T.; Roger, E.; Pierrot, C.; Mai, A.; Gissot, M. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1-11 - issn: 0924-8579 - wos: WOS:000784446400008 (14) - scopus: 2-s2.0-85124124624 (14)

11573/1664310 - 2022 - Modulation of virulence-associated traits in Aspergillus fumigatus by BET Inhibitor JQ1
Orekhova, Anastasia; De Angelis, Marta; Cacciotti, Andrea; Reverberi, Massimo; Rotili, Dante; Giorgi, Alessandra; Protto, Virginia; Bonincontro, Graziana; Fiorentino, Francesco; Zgoda, Victor; Mai, Antonello; Palamara, Anna Teresa; Simonetti, Giovanna - 01a Articolo in rivista
paper: MICROORGANISMS (Basel: MDPI) pp. 1-19 - issn: 2076-2607 - wos: WOS:000895665300001 (2) - scopus: 2-s2.0-85144917834 (4)

11573/1614439 - 2022 - Cytoplasmic HDAC4 regulates the membrane repair mechanism in Duchenne muscular dystrophy
Renzini, A.; Marroncelli, N.; Cavioli, G.; Di Francescantonio, S.; Forcina, L.; Lambridis, A.; Di Giorgio, E.; Valente, S.; Mai, A.; Brancolini, C.; Giampietri, C.; Magenta, A.; De Santa, F.; Adamo, S.; Coletti, D.; Moresi, V. - 01a Articolo in rivista
paper: JOURNAL OF CACHEXIA, SARCOPENIA AND MUSCLE (Heidelberg ; Berlin : Springer) pp. 1339-1359 - issn: 2190-5991 - wos: WOS:000755498900001 (13) - scopus: 2-s2.0-85124595217 (12)

11573/1622835 - 2022 - The nitrobenzoxadiazole derivative NBDHEX behaves as plasmodium falciparum gametocyte selective inhibitor with malaria parasite transmission blocking activity
Siciliano, G.; Di Paolo, V.; Rotili, D.; Migale, R.; Pedini, F.; Casella, M.; Camerini, S.; Dalzoppo, D.; Henderson, R.; Huijs, T.; Dechering, K. J.; Mai, A.; Caccuri, A. M.; Lalle, M.; Quintieri, L.; Alano, P. - 01a Articolo in rivista
paper: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. 1-19 - issn: 1424-8247 - wos: WOS:000825152000002 (5) - scopus: 2-s2.0-85123900571 (5)

11573/1657657 - 2022 - Potent and Specific Activators for Mitochondrial Sirtuins Sirt3 and Sirt5
Suenkel, Benjamin; Valente, Sergio; Zwergel, Clemens; Weiss, Sandra; Di Bello, Elisabetta; Fioravanti, Rossella; Aventaggiato, Michele; Amorim, João A.; Garg, Neha; Kumar, Surinder; Lombard, David B.; Hu, Tuo; Singh, Pankaj K.; Tafani, Marco; Palmeira, Carlos M.; Sinclair, David; Mai, Antonello; Steegborn, Clemens - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 14015-14031 - issn: 0022-2623 - wos: WOS:000878509000001 (23) - scopus: 2-s2.0-85140303478 (26)

11573/1628559 - 2022 - Biochemical functions and clinical characterizations of the sirtuins in diabetes-induced retinal pathologies
Taurone, Samanta; De Ponte, Chiara; Rotili, Dante; De Santis, Elena; Mai, Antonello; Fiorentino, Francesco; Scarpa, Susanna; Artico, Marco; Micera, Alessandra - 01g Articolo di rassegna (Review)
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000782009200001 (13) - scopus: 2-s2.0-85127570606 (13)

11573/1623442 - 2022 - Targeting the anti-apoptotic Bcl-2 family proteins: Machine learning virtual screening and biological evaluation of new small molecules
Valentini, E.; D'aguanno, S.; Di Martile, M.; Montesano, C.; Ferraresi, V.; Patsilinakos, A.; Sabatino, M.; Antonini, L.; Chiacchiarini, M.; Valente, S.; Mai, A.; Colotti, G.; Ragno, R.; Trisciuoglio, D.; Del Bufalo, D. - 01a Articolo in rivista
paper: THERANOSTICS (Wyoming, N.S.W. : Ivyspring International Publisher, 2011-) pp. 2427-2444 - issn: 1838-7640 - wos: WOS:000766737800003 (22) - scopus: 2-s2.0-85126080507 (20)

11573/1503800 - 2021 - Regulatory interplay between mir-181a-5p and estrogen receptor signaling cascade in breast cancer
Benedetti, R.; Papulino, C.; Sgueglia, G.; Chianese, U.; De Marchi, T.; Iovino, F.; Rotili, D.; Mai, A.; Nimeus, E.; Aversana, C. D.; Altucci, L. - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. 1-19 - issn: 2072-6694 - wos: WOS:000614992800001 (10) - scopus: 2-s2.0-85100578967 (14)

11573/1503669 - 2021 - Amphetamine modulation of long-term object recognition memory in rats: influence of stress
Colucci, Paola; Santori, Alessia; Romanelli, Luca; Zwergel, Clemens; Mai, Antonello; Scaccianoce, Sergio; Campolongo, Patrizia - 01a Articolo in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000626890500001 (1) - scopus: 2-s2.0-85102336381 (0)

11573/1541036 - 2021 - The two-faced role of SIRT6 in cancer
Fiorentino, F.; Carafa, V.; Favale, G.; Altucci, L.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
paper: CANCERS (Basel: MDPI) pp. 1-26 - issn: 2072-6694 - wos: WOS:000627939700001 (39) - scopus: 2-s2.0-85102076188 (42)

11573/1585511 - 2021 - Emerging therapeutic potential of SIRT6 modulators
Fiorentino, F.; Mai, A.; Rotili, D. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9732-9758 - issn: 0022-2623 - wos: WOS:000677581000007 (46) - scopus: 2-s2.0-85110981411 (45)

11573/1585447 - 2021 - Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein-protein interactions
Fiorentino, F.; Rotili, D.; Mai, A.; Bolla, J. R.; Robinson, C. V. - 01a Articolo in rivista
paper: CHEMICAL COMMUNICATIONS (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 10747-10750 - issn: 1359-7345 - wos: WOS:000700904000001 (9) - scopus: 2-s2.0-85117218452 (10)

11573/1585389 - 2021 - Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives
Fiorentino, Francesco; De Angelis, Marta; Menna, Martina; Rovere, Annarita; Maria Caccuri, Anna; D'acunzo, Francesca; Palamara, Anna Teresa; Nencioni, Lucia; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 2128-2138 - issn: 1475-6366 - wos: WOS:000700847900001 (5) - scopus: 2-s2.0-85116047224 (5)

11573/1611281 - 2021 - Metabolic rewiring by loss of sirt5 promotes kras-induced pancreatic cancer progression
Hu, T.; Shukla, S. K.; Vernucci, E.; He, C.; Wang, D.; King, R. J.; Jha, K.; Siddhanta, K.; Mullen, N. J.; Attri, K. S.; Murthy, D.; Chaika, N. V.; Thakur, R.; Mulder, S. E.; Pacheco, C. G.; Fu, X.; High, R. R.; Yu, F.; Lazenby, A.; Steegborn, C.; Lan, P.; Mehla, K.; Rotili, D.; Chaudhary, S.; Valente, S.; Tafani, M.; Mai, A.; Auwerx, J.; Verdin, E.; Tuveson, D.; Singh, P. K. - 01a Articolo in rivista
paper: GASTROENTEROLOGY (USA: Elsevier Philadelphia, PA: W B Saunders Company) pp. 1584-1600 - issn: 0016-5085 - wos: WOS:000711484200002 (66) - scopus: 2-s2.0-85115084196 (70)

11573/1447549 - 2021 - Downregulation of miR-326 and its host gene β-arrestin1 induces pro survival activity of E2F1 and promotes medulloblastoma growth
Miele, Evelina; Po, Agnese; Mastronuzzi, Angela; Carai, Andrea; Besharat, Zein Mersini; Pediconi, Natalia; Abballe, Luana; Catanzaro, Giuseppina; Sabato, Claudia; De Smaele, Enrico; Canettieri, Gianluca; Di Marcotullio, Lucia; Vacca, Alessandra; Mai, Antonello; Levrero, Massimo; Pfister, Stefan M; Kool, Marcel; Giangaspero, Felice; Locatelli, Franco; Ferretti, Elisabetta - 01a Articolo in rivista
paper: MOLECULAR ONCOLOGY (Amsterdam : Elsevier Science) pp. - - issn: 1574-7891 - wos: WOS:000603687900001 (10) - scopus: 2-s2.0-85098446777 (9)

11573/1576703 - 2021 - Sirt5 inhibition induces brown fat-like phenotype in 3t3-l1 preadipocytes
Molinari, Francesca; Feraco, Alessandra; Mirabilii, Simone; Saladini, Serena; Sansone, Luigi; Vernucci, Enza; Tomaselli, Giada; Marzolla, Vincenzo; Rotili, Dante; A Russo, Matteo; Ricciardi, Maria Rosaria; Tafuri, Agostino; Mai, Antonello; Caprio, Massimiliano; Tafani, Marco; Armani, Andrea - 01a Articolo in rivista
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 1-17 - issn: 2073-4409 - wos: WOS:000654660100001 (21) - scopus: 2-s2.0-85107437198 (22)

11573/1564224 - 2021 - Histone-deacetylase 8 drives the immune response and the growth of glioma
Mormino, Alessandro; Cocozza, Germana; Fontemaggi, Giulia; Valente, Sergio; Esposito, Vincenzo; Santoro, Antonio; Bernardini, Giovanni; Santoni, Angela; Fazi, Francesco; Mai, Antonello; Limatola, Cristina; Garofalo, Stefano - 01a Articolo in rivista
paper: GLIA (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 1-17 - issn: 0894-1491 - wos: WOS:000678875900001 (17) - scopus: 2-s2.0-85111697220 (17)

11573/1601697 - 2021 - First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53
Nowak, R. P.; Tumber, A.; Hendrix, E.; Ansari, M. S. Z.; Sabatino, M.; Antonini, L.; Andrijes, R.; Salah, E.; Mautone, N.; Pellegrini, F. R.; Simelis, K.; Kawamura, A.; Johansson, C.; Passeri, D.; Pellicciari, R.; Ciogli, A.; Del Bufalo, D.; Ragno, R.; Coleman, M. L.; Trisciuoglio, D.; Mai, A.; Oppermann, U.; Schofield, C. J.; Rotili, D. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 17031-17050 - issn: 0022-2623 - wos: WOS:000754727400006 (10) - scopus: 2-s2.0-85120646873 (12)

11573/1601812 - 2021 - JQ1, inibitore delle proteine BET, riduce i fattori di virulenza e la patogenicità di Aspergillus fumigatus.
Orekhova, A.; De Angelis, M.; Protto, V.; Rotili, D.; Mai, A.; A. T., Palamara.; Simonetti, G - 04d Abstract in atti di convegno
conference: Nome convegno (Napoli)
book: 13° Congresso Nazionale della Società Italiana di Microbiologia Farmaceutica Obiettivi e Sfide della Microbiologia Moderna per la Difesa della Salute - ()

11573/1602903 - 2021 - Sex-dependent effects of the drugs of abuse amphetamine and the smart drug 3,4-methylenedioxypyrovalerone on fear memory generalization in rats
Riccardi, Eleonora; Blasi, Eleonora; Zwergel, Clemens; Mai, Antonello; Morena, Maria; Campolongo, Patrizia - 01a Articolo in rivista
paper: NEUROSCIENCE (Oxford: Elsevier Ltd. Oxford; New York: Pergamon Press) pp. - - issn: 0306-4522 - wos: WOS:000888591600010 (3) - scopus: 2-s2.0-85122538831 (3)

11573/1564901 - 2021 - Polycomb repressive complex 2 modulation through the development of EZH2–EED interaction inhibitors and EED binders
Tomassi, Stefano; Romanelli, Annalisa; Zwergel, Clemens; Valente, Sergio; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 11774-11797 - issn: 0022-2623 - wos: WOS:000692012400002 (25) - scopus: 2-s2.0-85114048578 (31)

11573/1467228 - 2021 - Novel Pyridine-Based Hydroxamates and 2'-Aminoanilides as Histone Deacetylase Inhibitors: Biochemical Profile and Anticancer Activity
Zwergel, Clemens; Di Bello, Elisabetta; Fioravanti, Rossella; Conte, Mariarosaria; Nebbioso, Angela; Mazzone, Roberta; Brosch, Gerald; Mercurio, Ciro; Varasi, Mario; Altucci, Lucia; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 989-999 - issn: 1860-7179 - wos: WOS:000599084500001 (11) - scopus: 2-s2.0-85097525146 (10)

11573/1545865 - 2021 - Sirtuins
Zwergel, Clemens; Tomaselli, Daniela; Mai, Antonello - 02d Voce di Enciclopedia/Dizionario
book: Encyclopedia of Molecular Pharmacology - (978-3-030-21573-6)

11573/1408683 - 2020 - The pan-sirtuin inhibitor MC2494 regulates mitochondrial function in a leukemia cell line
Carafa, Vincenzo; Russo, Rosita; Della Torre, Laura; Cuomo, Francesca; Dell'aversana, Carmela; Sarno, Federica; Sgueglia, Giulia; Di Donato, Marzia; Rotili, Dante; Mai, Antonello; Nebbioso, Angela; Cobellis, Gilda; Chambery, Angela; Altucci, Lucia - 01a Articolo in rivista
paper: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. - - issn: 2234-943X - wos: WOS:000539644000001 (9) - scopus: 2-s2.0-85085984851 (9)

11573/1414757 - 2020 - Discovery of the first human arylsulfatase a reversible inhibitor impairing mouse oocyte fertilization
Caroselli, Silvia; Zwergel, Clemens; Pirolli, Adele; Sabatino, Manuela; Xu, Zhanjie; Kirsch, Gilbert; Mai, Antonello; Colotti, Gianni; Altieri, Fabio; Canipari, Rita; Valente, Sergio; Ragno, Rino - 01a Articolo in rivista
paper: ACS CHEMICAL BIOLOGY (AMERICAN CHEMICAL SOCiety, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036) pp. 1349-1357 - issn: 1554-8929 - wos: WOS:000543662300010 (4) - scopus: 2-s2.0-85086748074 (4)

11573/1434640 - 2020 - CDK9 as a valuable target in cancer: from natural compounds inhibitors to current treatment in pediatric soft tissue sarcomas
Cassandri, Matteo; Fioravanti, Rossella; Pomella, Silvia; Valente, Sergio; Rotili, Dante; Del Baldo, Giada; De Angelis, Biagio; Rota, Rossella; Mai, Antonello - 01a Articolo in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000565986100001 (27) - scopus: 2-s2.0-85089884656 (32)

11573/1429750 - 2020 - Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni
Coutinho Carneiro, V.; De Abreu Da Silva, I. C.; Amaral, M. S.; Pereira, A. S. A.; Silveira, G. O.; Pires, D. D. S.; Verjovski-Almeida, S.; Dekker, F. J.; Rotili, D.; Mai, A.; Lopes-Torres, E. J.; Robaa, D.; Sippl, W.; Pierce, R. J.; Borrello, M. T.; Ganesan, A.; Lancelot, J.; Thiengo, S.; Fernandez, M. A.; Vicentino, A. R. R.; Mourao, M. M.; Coelho, F. S.; Fantappie, M. R. - 01a Articolo in rivista
paper: PLOS NEGLECTED TROPICAL DISEASES (San Francisco, CA : Public Library of Science) pp. - - issn: 1935-2735 - wos: WOS:000547527200003 (6) - scopus: 2-s2.0-85087471659 (7)

11573/1418417 - 2020 - The innovative potential of statins in cancer: new targets for new therapies
Di Bello, Elisabetta; Zwergel, Clemens; Mai, Antonello; Valente, Sergio - 01g Articolo di rassegna (Review)
paper: FRONTIERS IN CHEMISTRY (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-2646 - wos: WOS:000546786300001 (78) - scopus: 2-s2.0-85087290374 (82)

11573/1382315 - 2020 - Tranylcypromine-based LSD1 inhibitors: structure-activity relationships, antiproliferative effects in leukemia, and gene target modulation
Fioravanti, R.; Romanelli, A.; Mautone, N.; Di Bello, E.; Rovere, A.; Corinti, D.; Zwergel, C.; Valente, S.; Rotili, D.; Botrugno, O. A.; Dessanti, P.; Vultaggio, S.; Vianello, P.; Cappa, A.; Binda, C.; Mattevi, A.; Minucci, S.; Mercurio, C.; Varasi, M.; Mai, A. - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 643-658 - issn: 1860-7179 - wos: WOS:000513271600001 (19) - scopus: 2-s2.0-85079446800 (22)

11573/1425034 - 2020 - Targeting histone acetylation/deacetylation in parasites: an update (2017–2020)
Fioravanti, Rossella; Mautone, Nicola; Rovere, Annarita; Rotili, Dante; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: CURRENT OPINION IN CHEMICAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 65-74 - issn: 1367-5931 - wos: WOS:000568781700011 (42) - scopus: 2-s2.0-85086940284 (44)

11573/1429805 - 2020 - Properly substituted cyclic Bis-(2-bromobenzylidene) compounds behaved as dual p300/CARM1 Inhibitors and Induced apoptosis in cancer cells
Fioravanti, Rossella; Tomassi, Stefano; Di Bello, Elisabetta; Romanelli, Annalisa; Plateroti, Andrea Maria; Benedetti, Rosaria; Conte, Mariarosaria; Novellino, Ettore; Altucci, Lucia; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:000558002500001 (4) - scopus: 2-s2.0-85088202424 (5)

11573/1585515 - 2020 - Lysine acetyltransferase inhibitors from natural sources
Fiorentino, F.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. 1-15 - issn: 1663-9812 - wos: WOS:000565346900001 (24) - scopus: 2-s2.0-85089907540 (26)

11573/1585513 - 2020 - HAT inhibitors in cancer therapy
Fiorentino, Francesco; Mai, Antonello; Rotili, Dante - 02a Capitolo o Articolo
book: Histone modifications in therapy - (9780128164228)

11573/1503814 - 2020 - Diphenylene Iodonium Is a Noncovalent MAO Inhibitor: A Biochemical and Structural Analysis
Iacovino, L. G.; Reis, J.; Mai, A.; Binda, C.; Mattevi, A. - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1394-1397 - issn: 1860-7179 - wos: WOS:000539090800001 (6) - scopus: 2-s2.0-85086146476 (6)

11573/1401342 - 2020 - Identification of Inhibitors to trypanosoma cruzi sirtuins based on compounds developed to human enzymes
Matutino Bastos, Tanira; Botelho Pereira Soares, Milena; Haddad Franco, Caio; Alcântara, Laura; Antonini, Lorenzo; Sabatino, Manuela; Mautone, Nicola; Holanda Freitas-Junior, Lucio; Moraes, Carolina Borsoi; Ragno, Rino; Rotili, Dante; Schenkman, Sergio; Mai, Antonello; Silvio Moretti, Nilmar - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000539312100255 (10) - scopus: 2-s2.0-85085293622 (11)

11573/1384850 - 2020 - Sirtuin modulators: where are we now? A review of patents from 2015 to 2019
Mautone, Nicola; Zwergel, Clemens; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. - - issn: 1354-3776 - wos: WOS:000526337100001 (44) - scopus: 2-s2.0-85083571564 (45)

11573/1390392 - 2020 - Altered mitochondrial function in cells carrying a premutation or unmethylated full mutation of the FMR1 gene
Nobile, V.; Palumbo, F.; Lanni, S.; Ghisio, V.; Vitali, A.; Castagnola, M.; Marzano, V.; Maulucci, G.; De Angelis, C.; De Spirito, M.; Pacini, L.; D'andrea, L.; Ragno, R.; Stazi, G.; Valente, S.; Mai, A.; Chiurazzi, P.; Genuardi, M.; Neri, G.; Tabolacci, E. - 01a Articolo in rivista
paper: HUMAN GENETICS (Germany: Springer Verlag Germany) pp. 227-245 - issn: 0340-6717 - wos: WOS:000515839900006 (19) - scopus: 2-s2.0-85077526115 (18)

11573/1390388 - 2020 - Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation
Ravasio, R.; Ceccacci, E.; Nicosia, L.; Hosseini, A.; Rossi, P. L.; Barozzi, I.; Fornasari, L.; Zuffo, R. D.; Valente, S.; Fioravanti, R.; Mercurio, C.; Varasi, M.; Mattevi, A.; Mai, A.; Pavesi, G.; Bonaldi, T.; Minucci, S. - 01a Articolo in rivista
paper: SCIENCE ADVANCES (Washington, DC : American Association for the Advancement of Science, 2015-) pp. - - issn: 2375-2548 - wos: WOS:000525751400003 (55) - scopus: 2-s2.0-85083269142 (57)

11573/1390390 - 2020 - A closer look into NADPH oxidase inhibitors: validation and insight into their mechanism of action
Reis, J.; Massari, M.; Marchese, S.; Ceccon, M.; Aalbers, F. S.; Corana, F.; Valente, S.; Mai, A.; Magnani, F.; Mattevi, A. - 01a Articolo in rivista
paper: REDOX BIOLOGY (Amsterdam : Elsevier) pp. - - issn: 2213-2317 - wos: WOS:000537459900002 (62) - scopus: 2-s2.0-85079650979 (68)

11573/1394955 - 2020 - Design of first-in-class dual EZH2/HDAC inhibitor: biochemical activity and biological evaluation in cancer cells
Romanelli, Annalisa; Stazi, Giulia; Fioravanti, Rossella; Zwergel, Clemens; Di Bello, Elisabetta; Pomella, Silvia; Perrone, Clara; Battistelli, Cecilia; Strippoli, Raffaele; Tripodi, Marco; Del Bufalo, Donatella; Rota, Rossella; Trisciuoglio, Daniela; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 977-983 - issn: 1948-5875 - wos: WOS:000535281200056 (51) - scopus: 2-s2.0-85087681122 (54)

11573/1412895 - 2020 - Detrimental effects of the 'bath salt' methylenedioxypyrovalerone on social play behavior in male rats
Schiavi, Sara; Melancia, Francesca; Carbone, Emilia; Buzzelli, Valeria; Manduca, Antonia; Peinado, Patricia Jiménez; Zwergel, Clemens; Mai, Antonello; Campolongo, Patrizia; Vanderschuren, Louk J M J; Trezza, Viviana - 01a Articolo in rivista
paper: NEUROPSYCHOPHARMACOLOGY (Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680) pp. 2012-2019 - issn: 0893-133X - wos: WOS:000539813000001 (4) - scopus: 2-s2.0-85086048601 (6)

11573/1480930 - 2020 - Recent advances in epigenetic proteolysis targeting chimeras (Epi-PROTACs)
Tomaselli, D.; Mautone, N.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000591227400031 (16) - scopus: 2-s2.0-85089918812 (15)

11573/1408685 - 2020 - Sirt4: a multifaceted enzyme at the crossroads of mitochondrial metabolism and cancer
Tomaselli, D.; Steegborn, C.; Mai, A.; Rotili, D. - 01g Articolo di rassegna (Review)
paper: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. - - issn: 2234-943X - wos: WOS:000531334700001 (55) - scopus: 2-s2.0-85083986337 (60)

11573/1389775 - 2020 - From PARP1 to TNKS2 inhibition: A structure-based approach
Tomassi, Stefano; Pfahler, Julian; Mautone, Nicola; Rovere, Annarita; Esposito, Chiara; Passeri, Daniela; Pellicciari, Roberto; Novellino, Ettore; Pannek, Martin; Steegborn, Clemens; Paiardini, Alessandro; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. - - issn: 1948-5875 - wos: WOS:000535281200039 (11) - scopus: 2-s2.0-85087107488 (9)

11573/1364390 - 2020 - Novel quinoline compounds active in cancer cells through coupled DNA methyltransferase inhibition and degradation
Zwergel, C.; Fioravanti, R.; Stazi, G.; Sarno, F.; Battistelli, C.; Romanelli, A.; Nebbioso, A.; Mendes, E.; Paulo, A.; Strippoli, R.; Tripodi, M.; Pechalrieu, D.; Arimondo, P. B.; De Luca, T.; Del Bufalo, D.; Trisciuoglio, D.; Altucci, L.; Valente, S.; Mai, A. - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000522477300193 (7) - scopus: 2-s2.0-85079504263 (7)

11573/1216108 - 2019 - Acute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the rat
Atehortua Martinez, Luisa Alessandra; Masniere, Cyriaque; Campolongo, Patrizia; Chasseigneaux, Stéphanie; Callebert, Jacques; Zwergel, Clemens; Mai, Antonello; Laplanche, Jean-Louis; Chen, Huixiong; Etheve-Quelquejeu, Mélanie; Mégarbane, Bruno; Benturquia, Nadia - 01a Articolo in rivista
paper: JOURNAL OF PSYCHOPHARMACOLOGY (Sage Publications Limited:6 Bonhill Street, London EC2A 4PU United Kingdom:011 44 207 3740645, EMAIL: journals@sagepub.co.uk, INTERNET: http://www.sagepub.co.uk/ltd_home.htm, Fax: 011 44 207 3748741) pp. 392-405 - issn: 0269-8811 - wos: WOS:000461559100013 (20) - scopus: 2-s2.0-85060763371 (21)

11573/1355613 - 2019 - H19-dependent transcriptional regulation of β3 and β4 integrins upon estrogen and hypoxia favors metastatic potential in prostate cancer
Bacci, L.; Aiello, A.; Ripoli, C.; Loria, R.; Pugliese, D.; Pierconti, F.; Rotili, D.; Strigari, L.; Pinto, F.; Bassi, P. F.; Mai, A.; Grassi, C.; Pontecorvi, A.; Falcioni, R.; Farsetti, A.; Nanni, S. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000484411100169 (23) - scopus: 2-s2.0-85071378179 (22)

11573/1355598 - 2019 - Inhibition of histone demethylases LSD1 and UTX regulates ERα signaling in breast cancer
Benedetti, R.; Dell'aversana, C.; De Marchi, T.; Rotili, D.; Liu, N. Q.; Novakovic, B.; Boccella, S.; Di Maro, S.; Cosconati, S.; Baldi, A.; Nimeus, E.; Schultz, J.; Hoglund, U.; Maione, S.; Papulino, C.; Chianese, U.; Iovino, F.; Federico, A.; Mai, A.; Stunnenberg, H. G.; Nebbioso, A.; Altucci, L. - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000507382100204 (36) - scopus: 2-s2.0-85077269849 (38)

11573/1193778 - 2019 - Identification of novel quinazoline derivatives as potent antiplasmodial agents
Bouchut, A; Rotili, D; Pierrot, C; Valente, S; Lafitte, S; Schultz, J; Hoglund, U; Mazzone, R; Lucidi, A; Fabrizi, G; Pechalrieu, D; Arimondo, Pb; Skinner-Adams, Ts; Chua, Mj; Andrews, Kt; Mai, A; Khalife, J. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 277-291 - issn: 0223-5234 - wos: WOS:000451498200018 (47) - scopus: 2-s2.0-85055197167 (49)

11573/1336693 - 2019 - Enzymatic and biological characterization of novel sirtuin modulators against cancer
Carafa, V.; Poziello, A.; Torre, L. D.; Giovannelli, P.; Di Donato, M.; Safadeh, E.; Yu, Z.; Baldi, A.; Castoria, G.; Tomaselli, D.; Mai, A.; Rotili, D.; Nebbioso, A.; Altucci, L. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000502786800136 (11) - scopus: 2-s2.0-85074828780 (13)

11573/1333610 - 2019 - Amphetamine and the Smart Drug 3,4-Methylenedioxypyrovalerone (MDPV) Induce Generalization of Fear Memory in Rats
Colucci, Paola; Mancini, Giulia Federica; Santori, Alessia; Zwergel, Clemens; Mai, Antonello; Trezza, Viviana; Roozendaal, Benno; Campolongo, Patrizia - 01a Articolo in rivista
paper: FRONTIERS IN MOLECULAR NEUROSCIENCE (Lausanne: Frontiers Research Foundation, 2008-) pp. - - issn: 1662-5099 - wos: WOS:000502730100001 (11) - scopus: 2-s2.0-85076905906 (11)

11573/1390394 - 2019 - The Protein Arginine Methyltransferases 1 and 5 affect Myc properties in glioblastoma stem cells
Favia, A.; Salvatori, L.; Nanni, S.; Iwamoto-Stohl, L. K.; Valente, S.; Mai, A.; Scagnoli, F.; Fontanella, R. A.; Totta, P.; Nasi, S.; Illi, B. - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 15925- - issn: 2045-2322 - wos: WOS:000493898100033 (32) - scopus: 2-s2.0-85074323285 (32)

11573/1336760 - 2019 - DNA Methylation: Biological Implications and Modulation of Its Aberrant Dysregulation
Lucidi, Alessia; Tomaselli, Daniela; Rotili, Dante; Mai, Antonello - 02a Capitolo o Articolo
book: The DNA, RNA, and Histone Methylomes - (978-3-030-14791-4; 978-3-030-14792-1)

11573/1390399 - 2019 - Statins and histone deacetylase inhibitors affect lamin A/C - histone deacetylase 2 interaction in human cells
Mattioli, Elisabetta; Andrenacci, Davide; Mai, Antonello; Valente, Sergio; Robijns, Joke; De Vos, Winnok H; Capanni, Cristina; Lattanzi, Giovanna - 01a Articolo in rivista
paper: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-634X - wos: WOS:000467197300001 (18) - scopus: 2-s2.0-85075855435 (15)

11573/1238934 - 2019 - The emerging role of epigenetics in human autoimmune disorders
Mazzone, Roberta; Zwergel, Clemens; Artico, Marco; Taurone, Samanta; Ralli, Massimo; Greco, Antonio; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. - - issn: 1868-7083 - wos: WOS:000459879000001 (178) - scopus: 2-s2.0-85062452532 (208)

11573/1336715 - 2019 - Structure-reactivity relationships on substrates and inhibitors of the lysine deacylase sirtuin 2 from schistosoma mansoni (SmSirt2)
Monaldi, Daria; Rotili, Dante; Julien Lancelot, ‡; Martin Marek, §; Nathalie Wössner, ∥; Lucidi, Alessia; Tomaselli, Daniela; Elizabeth Ramos-Morales, ‡; Christophe Romier, ∥; Pierce, ∥ Raymond J.; Mai, Antonello; And Manfred Jung, ‡ - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8733-8759 - issn: 0022-2623 - wos: WOS:000490355000005 (20) - scopus: 2-s2.0-85072924967 (19)

11573/1221842 - 2019 - Effect of α-methoxy substitution on the anti-HIV activity of dihydropyrimidin-4(3 H)-ones
Nawrozkij, Maxim B.; Forgione, Mariantonietta; Yablokov, Alexandre S.; Lucidi, Alessia; Tomaselli, Daniela; Patsilinakos, Alexandros; Panella, Cristina; Hailu, Gebremedhin S.; Kirillov, Ivan A.; Badia, Roger; Riveira-Munoz, Eva; Crespan, Emmanuele; Armijos Rivera, Jorge I.; Cirilli, Roberto; Ragno, Rino; Esté, José A.; Maga, Giovanni; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 604-621 - issn: 0022-2623 - wos: WOS:000457067600015 (14) - scopus: 2-s2.0-85059424455 (12)

11573/1336742 - 2019 - α,γ-Diketocarboxylic acids and their esters act as carbonic anhydrase IX and XII selective inhibitors
Nocentini, Alessio; Lucidi, Alessia; Perut, Francesca; Massa, Annamaria; Tomaselli, Daniela; Gratteri, Paola; Baldini, Nicola; Rotili, Dante; Mai, Antonello; Supuran, Claudiu T. - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 661-665 - issn: 1948-5875 - wos: WOS:000464767700047 (18) - scopus: 2-s2.0-85064255109 (19)

11573/1339733 - 2019 - Epigenetic modulators as a new strategies to reduce Aspergillus pathogenicity
Orekhova, Anastasia; D’Auria, F. D.; Rotili, D.; Mai, A.; Palamara, A. T.; Simonetti, G - 04f Poster
conference: 47° Congresso Nazionale della Società Italiana di Microbiologia (Roma)
book: 47° Congresso Nazionale della Società Italiana di Microbiologia - ()

11573/1390396 - 2019 - Histone deacetylases contribute to excitotoxicity-triggered degeneration of retinal ganglion cells in vivo
Schluter, A.; Aksan, B.; Fioravanti, R.; Valente, S.; Mai, A.; Mauceri, D. - 01a Articolo in rivista
paper: MOLECULAR NEUROBIOLOGY (Humana Press Incorporated:999 Riverview Drive, Suite 208:Totowa, NJ 07512:(973)256-1699, EMAIL: lglasner@humanapr.com, INTERNET: http://www.humanapress.com, Fax: (973)256-8341) pp. 8018-8034 - issn: 0893-7648 - wos: WOS:000494860800008 (23) - scopus: 2-s2.0-85067067374 (25)

11573/1355609 - 2019 - Comparison of the effects of synthetic and plant-derived mTOR regulators on healthy human ovarian cells
Sirotkin, A. V.; Adamcova, E.; Rotili, D.; Mai, A.; Mlyncek, M.; Mansour, L.; Alwasel, S.; Harrath, A. H. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF PHARMACOLOGY (AMSTERDAM, NETHERLANDS: ELSEVIER SCIENCE) pp. 70-78 - issn: 0014-2999 - wos: WOS:000468305200009 (1) - scopus: 2-s2.0-85063965408 (2)

11573/1339079 - 2019 - Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype
Stazi, G.; Taglieri, L.; Nicolai, Alice; Romanelli, A.; Fioravanti, R.; Morrone, S.; Sabatino, M.; Ragno, R.; Taurone, S.; Nebbioso, M.; Carletti, R.; Artico, M.; Valente, S.; Scarpa, S.; Mai, A. - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. 1-17 - issn: 1868-7083 - wos: WOS:000501362500004 (52) - scopus: 2-s2.0-85076062797 (50)

11573/1208206 - 2019 - Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells
Stazi, Giulia; Battistelli, Cecilia; Piano, Valentina; Mazzone, Roberta; Marrocco, Biagina; Marchese, Sara; Louie, Sharon M.; Zwergel, Clemens; Antonini, Lorenzo; Patsilinakos, Alexandros; Ragno, Rino; Viviano, Monica; Sbardella, Gianluca; Ciogli, Alessia; Fabrizi, Giancarlo; Cirilli, Roberto; Strippoli, Raffaele; Marchetti, Alessandra; Tripodi, Marco; Nomura, Daniel K.; Mattevi, Andrea; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 722-735 - issn: 0223-5234 - wos: WOS:000458597300053 (16) - scopus: 2-s2.0-85058530369 (17)

11573/1416968 - 2019 - Histone deacetylases as an epigenetic pillar for the development of hybrid inhibitors in cancer
Stazi, Giulia; Fioravanti, Rossella; Mai, Antonello; Mattevi, Andrea; Valente, Sergio - 01g Articolo di rassegna (Review)
paper: CURRENT OPINION IN CHEMICAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 89-100 - issn: 1367-5931 - wos: WOS:000473839100012 (27) - scopus: 2-s2.0-85064167463 (30)

11573/1275490 - 2019 - Epigenetic Pharmacology in Regenerative Medicine (Epi-Drugs)
Stazi, Giulia; Zwergel, Clemens; Valente, Sergio; Mai, Antonello - 02a Capitolo o Articolo
book: Epigenetics and Regeneration - (9780128148792)

11573/1336730 - 2019 - Epigenetic polypharmacology: a new frontier for epi-drug discovery
Tomaselli, Daniela; Lucidi, Alessia; Rotili, Dante; Mai, Antonello - 01g Articolo di rassegna (Review)
paper: MEDICINAL RESEARCH REVIEWS ([New York, N.Y.] : Wiley) pp. 190-244 - issn: 1098-1128 - wos: WOS:000534635500009 (80) - scopus: 2-s2.0-85075138650 (89)

11573/1355602 - 2019 - Histone deacetylase inhibitors exert anti-tumor effects on human adherent and stem-like glioma cells 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis
Was, H.; Krol, S. K.; Rotili, D.; Mai, A.; Wojtas, B.; Kaminska, B.; Maleszewska, M. - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. 11- - issn: 1868-7083 - wos: WOS:000456005400002 (57) - scopus: 2-s2.0-85060173887 (56)

11573/1275422 - 2019 - Sirtuins as drug targets
Zwergel, Clemens; Rotili, Dante; Valente, Sergio; Mai, Antonello - 02a Capitolo o Articolo
book: Epigenetic Drug Discovery - (9783527343140; 9783527809257)

11573/1265927 - 2019 - Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells
Zwergel, Clemens; Schnekenburger, Michael; Sarno, Federica; Battistelli, Cecilia; Manara, Maria Cristina; Stazi, Giulia; Mazzone, Roberta; Fioravanti, Rossella; Gros, Christina; Ausseil, Frédéric; Florean, Cristina; Nebbioso, Angela; Strippoli, Raffaele; Ushijima, Toshikazu; Scotlandi, Katia; Tripodi, Marco; Arimondo, Paola B.; Altucci, Lucia; Diederich, Marc; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. - - issn: 1868-7083 - wos: WOS:000467227900001 (28) - scopus: 2-s2.0-85065468885 (32)

11573/1147241 - 2018 - Epigenetic metalloenzymes
Blanquart, Christophe; Linot, Camille; Cartron, Pierre-Francois; Tomaselli, Daniela; Mai, Antonello; Bertrand, Philippe - 01a Articolo in rivista
paper: CURRENT MEDICINAL CHEMISTRY (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. - - issn: 0929-8673 - wos: WOS:000477048900011 (11) - scopus: 2-s2.0-85071053394 (15)

11573/1147229 - 2018 - Effects of class II-selective histone deacetylase inhibitor on neuromuscular function and disease progression in SOD1-ALS mice
Buonvicino, Daniela; Felici, Roberta; Ranieri, Giuseppe Antonio; Caramelli, Riccardo; Lapucci, Andrea; Cavone, Leonardo; Muzzi, Mirko; Di Pietro, Lorena; Bernardini, Camilla; Zwergel, Clemens; Valente, Sergio; Mai, Antonello; Chiarugi, Alberto - 01a Articolo in rivista
paper: NEUROSCIENCE (Oxford: Elsevier Ltd. Oxford; New York: Pergamon Press) pp. 228-238 - issn: 0306-4522 - wos: WOS:000430884100020 (19) - scopus: 2-s2.0-85044974964 (19)

11573/1116555 - 2018 - RIP1-HAT1-SirT complex identification and targeting in treatment and prevention of cancer
Carafa, Vincenzo; Nebbioso, Angela; Cuomo, Francesca; Rotili, Dante; Cobellis, Gilda; Bontempo, Paola; Baldi, Alfonso; Spugnini, Enrico P.; Citro, Alfonso Gennaro; Chambery, Angela; Russo, Rosita; Ciana, Paolo; Maravigna, Luca; Shaik, Jani; Radaelli, Enrico; De Antonellis, Pasquale; Tarantino, Domenico; Pirolli, Adele; Ragno, Rino; Massimo Zollo, .; Stunnenberg, Hendrik G.; Mai, Antonello; Altucci, Lucia - 01a Articolo in rivista
paper: CLINICAL CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 2886-2900 - issn: 1078-0432 - wos: WOS:000435462700019 (37) - scopus: 2-s2.0-85052287980 (40)

11573/1115449 - 2018 - KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2
Cocco, Elisa; Leo, Manuela; Canzonetta, Claudia; Di Vito, Serena; Mai, Antonello; Rotili, Dante; Di Napoli, Arianna; Vecchione, Andrea; De Nunzio, Cosimo; Filetici, Patrizia; Stoppacciaro, Antonella - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. 1-16 - issn: 1868-7083 - wos: WOS:000429840100001 (11) - scopus: 2-s2.0-85045003305 (16)

11573/1174048 - 2018 - Six years (2012-2018) of researches on catalytic EZH2 inhibitors: the boom of the 2-pyridone compounds
Fioravanti, R; Stazi, G; Zwergel, C; Valente, S; Mai, A. - 01a Articolo in rivista
paper: THE CHEMICAL RECORD (New York N.Y.: Wiley, c2000-) pp. 1818-1832 - issn: 1527-8999 - wos: WOS:000453386600014 (84) - scopus: 2-s2.0-85055289007 (87)

11573/1147231 - 2018 - Lysine acetyltransferase inhibitors: structure-activity relationships and potential therapeutic implications
Fiorentino, Francesco; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
paper: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 1067-1091 - issn: 1756-8919 - wos: WOS:000431874300008 (24) - scopus: 2-s2.0-85046873546 (24)

11573/1174039 - 2018 - Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells
Iachettini, Sara; Trisciuoglio, Daniela; Rotili, Dante; Lucidi, Alessia; Salvati, Erica; Zizza, Pasquale; Di Leo, Luca; Del Bufalo, Donatella; Rosa Ciriolo, Maria; Leonetti, Carlo; Steegborn, Clemens; Mai, Antonello; Rizzo, Angela; Annamaria Biroccio, And - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. 996- - issn: 2041-4889 - wos: WOS:000446267200026 (71) - scopus: 2-s2.0-85053859793 (80)

11573/1074176 - 2018 - Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors
Kalin, Jay H.; Wu, Muzhou; Gomez, Andrea V.; Song, Yun; Das, Jayanta; Hayward, Dawn; Adejola, Nkosi; Wu, Mingxuan; Panova, Izabela; Chung, Hye Jin; Kim, Edward; Roberts, Holly J.; Roberts, Justin M.; Prusevich, Polina; Jeliazkov, Jeliazko R.; Roy Burman, Shourya S.; Fairall, Louise; Milano, Charles; Eroglu, Abdulkerim; Proby, Charlotte M.; Dinkova-Kostova, Albena T.; Hancock, Wayne W.; Gray, Jeffrey J.; Bradner, James E.; Valente, Sergio; Mai, Antonello; Anders, Nicole M.; Rudek, Michelle A.; Hu, Yong; Ryu, Byungwoo; Schwabe, John W. R.; Mattevi, Andrea; Alani, Rhoda M.; Cole, Philip A. - 01a Articolo in rivista
paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. - - issn: 2041-1723 - wos: WOS:000419404200003 (206) - scopus: 2-s2.0-85040217796 (177)

11573/1147949 - 2018 - A quinoline-based DNA methyltransferase inhibitor as a possible adjuvant in osteosarcoma therapy
Manara, Maria Cristina; Valente, Sergio; Cristalli, Camilla; Nicoletti, Giordano; Landuzzi, Lorena; Zwergel, Clemens; Mazzone, Roberta; Stazi, Giulia; Arimondo, Paola B.; Pasello, Michela; Guerzoni, Clara; Picci, Piero; Nanni, Patrizia; Lollini, Pier-Luigi; Mai, Antonello; Scotlandi, Katia - 01a Articolo in rivista
paper: MOLECULAR CANCER THERAPEUTICS (Philadelphia, PA : American Association for Cancer Research, c2001-) pp. 1881-1892 - issn: 1535-7163 - wos: WOS:000444041300008 (32) - scopus: 2-s2.0-85053014459 (32)

11573/1147243 - 2018 - Altered modulation of lamin A/C-HDAC2 interaction and p21 expression during oxidative stress response in HGPS
Mattioli, Elisabetta; Andrenacci, Davide; Garofalo, Cecilia; Prencipe, Sabino; Scotlandi, Katia; Remondini, Daniel; Gentilini, Davide; Di Blasio, Anna Maria; Valente, Sergio; Scarano, Emanuela; Cicchilitti, Lucia; Piaggio, Giulia; Mai, Antonello; Lattanzi, Giovanna - 01a Articolo in rivista
paper: AGING CELL ([Oxford] : Blackwell Science Ltd, 2002-) pp. - - issn: 1474-9726 - wos: WOS:000445599100019 (34) - scopus: 2-s2.0-85052612287 (35)

11573/1147233 - 2018 - Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells
Mellini, Paolo; Marrocco, Biagina; Borovika, Diana; Polletta, Lucia; Carnevale, Ilaria; Saladini, Serena; Stazi, Giulia; Zwergel, Clemens; Trapencieris, Peteris; Ferretti, Elisabetta; Tafani, Marco; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: PHILOSOPHICAL TRANSACTIONS - ROYAL SOCIETY. BIOLOGICAL SCIENCES (Royal Society of London) pp. 20170150- - issn: 0962-8436 - wos: WOS:000430738400014 (20) - scopus: 2-s2.0-85045959069 (21)

11573/1147245 - 2018 - Nucleocytoplasmic export of HDAC5 and SIRT2 downregulation: two epigenetic mechanisms by which antidepressants enhance synaptic plasticity markers
Muñoz-Cobo, I.; Erburu, M. M.; Zwergel, C.; Cirilli, Raffaela; Mai, A.; Valente, S.; Puerta, E.; Tordera, Rosa M. - 01a Articolo in rivista
paper: PSYCHOPHARMACOLOGY (Heidelberg; Berlin: Springer) pp. 2831-2846 - issn: 0033-3158 - wos: WOS:000446140500005 (10) - scopus: 2-s2.0-85051492076 (9)

11573/1225570 - 2018 - EZH2, HIF-1, and their inhibitors: An overview on pediatric cancers
Papale, Marco; Ferretti, Elisabetta; Battaglia, Giuseppe; Bellavia, Diana; Mai, Antonello; Tafani, Marco - 01g Articolo di rassegna (Review)
paper: FRONTIERS IN PEDIATRICS (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-2360 - wos: WOS:000450498300001 (13) - scopus: 2-s2.0-85058208629 (13)

11573/1147237 - 2018 - Combined HAT/EZH2 modulation leads to cancer-selective cell death
Petraglia, Francesca; Singh, Abhishek A.; Carafa, Vincenzo; Nebbioso, Angela; Conte, Mariarosaria; Scisciola, Lucia; Valente, Sergio; Baldi, Alfonso; Mandoli, Amit; Petrizzi, Valeria Belsito; Ingenito, Concetta; De Falco, Sandro; Cicatiello, Valeria; Apicella, Ivana; Janssen-Megens, Eva M.; Kim, Bowon; Yi, Guoqiang; Logie, Colin; Heath, Simon; Ruvo, Menotti; Wierenga, Albertus T. J.; Flicek, Paul; Yaspo, Marie Laure; Della Valle, Veronique; Bernard, Olivier; Tomassi, Stefano; Novellino, Ettore; Feoli, Alessandra; Sbardella, Gianluca; Gut, Ivo; Vellenga, Edo; Stunnenberg, Hendrik G.; Mai, Antonello; Martens, Joost H. A.; Altucci, Lucia - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 25630-25646 - issn: 1949-2553 - wos: (0) - scopus: 2-s2.0-85047400725 (6)

11573/1120934 - 2018 - HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal
Rossi, Lucia; Battistelli, Cecilia; De Turris, Valeria; Noce, Valeria; Zwergel, Clemens; Valente, Sergio; Moioli, Alessandra; Manzione, Andrea; Palladino, Marco; Bordoni, Veronica; Domenici, Alessandro; Mene', Paolo; Mai, Antonello; Tripodi, Marco; Strippoli, Raffaele - 01a Articolo in rivista
paper: OPEN ACCESS SCIENTIFIC REPORTS (Los Angeles, CA : OMICS Publishing Group, [2012]-) pp. - - issn: 2332-2675 - wos: WOS:000433547600053 (24) - scopus: 2-s2.0-85048002226 (26)

11573/1065694 - 2018 - Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches
Sabatino, Manuela; Rotili, Dante; Patsilinakos, Alexandros; Forgione, Mariantonietta; Tomaselli, Daniela; Alby, Fréderic; Arimondo, Paola B.; Mai, Antonello; Ragno, Rino - 01a Articolo in rivista
paper: JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (-SPRINGER, VAN GODEWIJCKSTRAAT 30, DORDRECHT, NETHERLANDS, 3311 GZ -Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: frontoffice@wkap.nl, kluweronline@wkap.nl, INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254) pp. 435-458 - issn: 0920-654X - wos: WOS:000425293300003 (15) - scopus: 2-s2.0-85041359880 (16)

11573/1147239 - 2018 - Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia
Singh, Abhishek A.; Petraglia, Francesca; Nebbioso, Angela; Yi, Guoqiang; Conte, Mariarosaria; Valente, Sergio; Mandoli, Amit; Scisciola, Lucia; Lindeboom, Rik; Kerstens, Hinri; Janssen-Megens, Eva M.; Pourfarzad, Farzin; Habibi, Ehsan; Berentsen, Kim; Kim, Bowon; Logie, Colin; Heath, Simon; Wierenga, Albertus T. J.; Clarke, Laura; Flicek, Paul; Jansen, Joop H.; Kuijpers, Taco; Yaspo, Marie Laure; Della Valle, Veronique; Bernard, Olivier; Gut, Ivo; Vellenga, Edo; Stunnenberg, Hendrik G.; Mai, Antonello; Altucci, Lucia; Martens, Joost H. A. - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 25647-25660 - issn: 1949-2553 - wos: (0) - scopus: 2-s2.0-85047385574 (13)

11573/1202973 - 2018 - Application of small epigenetic modulators in pediatric medulloblastoma
Zwergel, Clemens; Romanelli, Annalisa; Stazi, Giulia; Besharat, Zein Mersini; Catanzaro, Giuseppina; Tafani, Marco; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: FRONTIERS IN PEDIATRICS (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-2360 - wos: WOS:000452081000001 (13) - scopus: 2-s2.0-85058706178 (15)

11573/1147235 - 2018 - Trends of LSD1 inhibitors in viral infections
Zwergel, Clemens; Stazi, Giulia; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 1133-1135 - issn: 1756-8919 - wos: WOS:000433568500001 (10) - scopus: 2-s2.0-85048066484 (10)

11573/955900 - 2017 - Essential oil extraction, chemical analysis and anti-candida activity of calamintha nepeta (L.) Savi subsp. glandulosa (Req.) ball-new approaches
Božovic, Mijat; Garzoli, Stefania; Sabatino, Manuela; Pepi, Federico; Baldisserotto, Anna; Andreotti, Elisa; Romagnoli, Carlo; Mai, Antonello; Manfredini, Stefano; Ragno, Rino - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:000395552400017 (30) - scopus: 2-s2.0-85013989667 (38)

11573/1602341 - 2017 - Corrigendum: Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma
Coni, S.; Mancuso, A. B.; Di Magno, L.; Sdruscia, G.; Manni, S.; Serrao, S. M.; Rotili, D.; Spiombi, E.; Bufalieri, F.; Petroni, M.; Kusio-Kobialka, M.; De Smaele, E.; Ferretti, E.; Capalbo, C.; Mai, A.; Niewiadomski, P.; Screpanti, I.; Di Marcotullio, L.; Canettieri, G. - 01b Commento, Erratum, Replica e simili
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000399974300001 (5) - scopus: 2-s2.0-85068766477 (4)

11573/946157 - 2017 - Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.
Coni, Sonia; Mancuso, Anna Barbara; Di Magno, L; Sdruscia, Giulia; Manni, Simona; Serrao, Silvia Maria; Rotili, Dante; Spiombi, Eleonora; Bufalieri, Francesca; Petroni, Marialaura; Kusio Kobialka, M; De Smaele, Enrico; Ferretti, Elisabetta; Capalbo, Carlo; Mai, Antonello; Niewiadomski, P; Screpanti, Isabella; Di Marcotullio, Lucia; Canettieri, Gianluca - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 44079- - issn: 2045-2322 - wos: WOS:000396136700001 (54) - scopus: 2-s2.0-85014895304 (54)

11573/1147224 - 2017 - Attenuation of diet-induced obesity and induction of white fat browning with a chemical inhibitor of histone deacetylases
Ferrari, A.; Fiorino, E.; Longo, R.; Barilla, S.; Mitro, N.; Cermenati, G.; Giudici, M.; Caruso, D.; Mai, A.; Guerrini, U.; De Fabiani, E.; Crestani, M. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF OBESITY (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 289-298 - issn: 0307-0565 - wos: WOS:000394143700012 (39) - scopus: 2-s2.0-85006511908 (44)

11573/944092 - 2017 - A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability.
Fulci, C; Rotili, Dante; De Luca, A; Stella, L; Morozzo Della Rocca, B; Forgione, M; Di Paolo, V; Mai, Antonello; Falconi, M; Quintieri, L; Caccuri, Am; 7, . - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 240-247 - issn: 1475-6366 - wos: WOS:000392591100017 (19) - scopus: 2-s2.0-85015590345 (19)

11573/1027812 - 2017 - Lysine deacetylase inhibitors in parasites: past, present, and future perspectives.
Hailu, Gs; Robaa, D; Forgione, M; Sippl, W; Rotili, D; Mai, A. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4780-4804 - issn: 0022-2623 - wos: WOS:000404202200002 (73) - scopus: 2-s2.0-85021131721 (76)

11573/1092479 - 2017 - Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice
Lapucci, Andrea; Cavone, Leonardo; Buonvicino, Daniela; Felici, Roberta; Gerace, Elisabetta; Zwergel, Clemens; Valente, Sergio; Mai, Antonello; Chiarugi, Alberto - 01a Articolo in rivista
paper: NEUROSCIENCE LETTERS (Limerick Ireland: Elsevier Science Ireland Limited) pp. 120-125 - issn: 0304-3940 - wos: WOS:000409288600019 (19) - scopus: 2-s2.0-85026360880 (22)

11573/1192249 - 2017 - Structure-activity relationships on cynnamoyl derivatives as inhibitors of p300 Histone acetyltransferase
Madia, Valentina Noemi; Benedetti, Rosaria; Letizia Barreca, Maria; Ngo, Liza; Pescatori, Luca; Messore, Antonella; Pupo, Giovanni; Saccoliti, Francesco; Valente, Sergio; Mai, Antonello; Scipione, Luigi; George Zheng, Yujun; Tintori, Cristina; Botta, Maurizio; Cecchetti, Violetta; Altucci, Lucia; Di Santo, Roberto; Costi, Roberta - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1359-1368 - issn: 1860-7187 - wos: WOS:000429592300014 (10) - scopus: 2-s2.0-85017448829 (9)

11573/972511 - 2017 - Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy
Mazzone, Roberta; Zwergel, Clemens; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. 1-15 - issn: 1868-7083 - wos: WOS:000403112500004 (112) - scopus: 2-s2.0-85020006586 (119)

11573/1017610 - 2017 - The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells
Miele, Evelina; Valente, Sergio; Alfano, Vincenzo; Silvano, Marianna; Mellini, Paolo; Borovika, Diana; Marrocco, Biagina; Po, Agnese; Besharat, Zein Mersini; Catanzaro, Giuseppina; Battaglia, Giuseppe; Abballe, Luana; Zwergel, Clemens; Stazi, Giulia; Milite, Ciro; Castellano, Sabrina; Tafani, Marco; Trapencieris, Peteris; Mai, Antonello; Ferretti, Elisabetta - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 68557-68570- - issn: 1949-2553 - wos: WOS:000410790500145 (36) - scopus: 2-s2.0-85040235337 (38)

11573/947675 - 2017 - Development of 1,2,4-oxadiazoles as potent and selective inhibitors of the human deacetylase sirtuin 2: structure-activity relationship, X-ray crystal structure, and anticancer activity
Moniot, S; Forgione, M; Lucidi, Alessia; Hailu, Gebremedhin Solomon; Nebbioso, A; Carafa, V; Baratta, F; Altucci, L; Giacché, N; Passeri, D; Pellicciari, R; Mai, Antonello; Steegborn, C; Rotili, Dante - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2344-2360 - issn: 0022-2623 - wos: WOS:000397546000013 (80) - scopus: 2-s2.0-85016147565 (84)

11573/944090 - 2017 - Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity.
Ourailidou, Me; Lenoci, A; Zwergel, Clemens; Rotili, Dante; Mai, Antonello; Dekker, F. J. 4. - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 847-856 - issn: 0968-0896 - wos: WOS:000394201900004 (9) - scopus: 2-s2.0-85008433321 (10)

11573/1418429 - 2017 - Metabolite profiling of ascidian Styela plicata using LC–MS with multivariate statistical analysis and their antitumor activity
Palanisamy, S. K.; Trisciuoglio, D.; Zwergel, C.; Del Bufalo, D.; Mai, A. - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 614-623 - issn: 1475-6366 - wos: WOS:000399579300001 (15) - scopus: 2-s2.0-85015046419 (16)

11573/1027813 - 2017 - Crystal structures of the mitochondrial deacylase Sirtuin 4 reveal isoform-specific acyl recognition and regulation features.
Pannek, M; Simic, Z; Fuszard, M; Meleshin, M; Rotili, D; Mai, A; Schutkowski, M; Steegborn, C. - 01a Articolo in rivista
paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. - - issn: 2041-1723 - wos: WOS:000415262500001 (73) - scopus: 2-s2.0-85034035870 (76)

11573/1017602 - 2017 - EZH2 inhibitors: a patent review (2014-2016)
Stazi, Giulia; Zwergel, Clemens; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 797-813 - issn: 1354-3776 - wos: WOS:000405302700004 (37) - scopus: 2-s2.0-85020639378 (39)

11573/1027810 - 2017 - The relevance of Ki calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor.
Wapenaar, H; Van Den Bosch, T; Leus, Ngj; Van Der Wouden, Pe; Eleftheriadis, N; Hermans, J; Hailu, Gs; Rotili, D; Mai, A; Dömling, A; Bischoff, R; Haisma, Hj; Dekker, F. J. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 480-486 - issn: 0223-5234 - wos: WOS:000403993500041 (6) - scopus: 2-s2.0-85019413230 (7)

11573/944091 - 2017 - Structural basis of sirtuin 6 activation by synthetic small molecules.
You, W; Rotili, Dante; Li, Tm; Kambach, C; Meleshin, M; Schutkowski, M; Chua, Kf; Mai, Antonello; Steegborn, C. 1. - 01a Articolo in rivista
paper: ANGEWANDTE CHEMIE. INTERNATIONAL EDITION (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 1007-1011 - issn: 1433-7851 - wos: WOS:000394997200011 (121) - scopus: 2-s2.0-85006998900 (131)

11573/955887 - 2017 - Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells
Zwergel, Clemens; Czepukojc, Brigitte; Evain Bana, Emilie; Xu, Zhanjie; Stazi, Giulia; Mori, Mattia; Patsilinakos, Alexandros; Mai, Antonello; Botta, Bruno; Ragno, Rino; Bagrel, Denise; Kirsch, Gilbert; Meiser, Peter; Jacob, Claus; Montenarh, Mathias; Valente, Sergio - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 316-333 - issn: 0223-5234 - wos: WOS:000401677500027 (25) - scopus: 2-s2.0-85017548581 (27)

11573/884147 - 2016 - Sirtuin functions and modulation: from chemistry to the clinic
Carafa, Vincenzo; Rotili, Dante; Forgione, Mariantonietta; Cuomo, Francesca; Serretiello, Enrica; Hailu, Gebremedhin Solomon; Jarho, Elina; Lahtela Kakkonen, Maija; Mai, Antonello; Altucci, Lucia - 01a Articolo in rivista
paper: CLINICAL EPIGENETICS (Berlin : Springer) pp. 1-21 - issn: 1868-7083 - wos: WOS:000376856700001 (288) - scopus: 2-s2.0-84973864104 (304)

11573/884154 - 2016 - Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells
Chano, Tokuhiro; Avnet, Sofia; Kusuzaki, Katsuyuki; Bonuccelli, Gloria; Sonveaux, Pierre; Rotili, Dante; Mai, Antonello; Baldini, Nicola - 01a Articolo in rivista
paper: AMERICAN JOURNAL OF CANCER RESEARCH (Madison, WI: Published by e-Century Publishing Corporation, Madison) pp. 859-875 - issn: 2156-6976 - wos: WOS:000384444300002 (31) - scopus: 2-s2.0-84991518619 (34)

11573/851423 - 2016 - Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model
Di Liddo, Rosa; Valente, Sergio; Taurone, Samanta; Zwergel, Clemens; Marrocco, Biagina; Turchetta, Rosaria; Conconi, Maria Teresa; Scarpa, Carlotta; Bertalot, Thomas; Schrenk, Sandra; Mai, Antonello; Artico, Marco - 01a Articolo in rivista
paper: AUTOIMMUNITY (Amsterdam; New York: Harwood Academic Publishers.) pp. 1-11 - issn: 0891-6934 - wos: (0) - scopus: 2-s2.0-84955134169 (19)

11573/884170 - 2016 - Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells
Di Martile, Marta; Desideri, Marianna; De Luca, Teresa; Gabellini, Chiara; Buglioni, Simonetta; Eramo, Adriana; Sette, Giovanni; Milella, Michele Stanislaw; Rotili, Dante; Mai, Antonello; Carradori, Simone; Secci, Daniela; De Maria, Ruggero; Del Bufalo, Donatella; Trisciuoglio, Daniela - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 11332-11348 - issn: 1949-2553 - wos: WOS:000375678300047 (38) - scopus: 2-s2.0-84962019515 (39)

11573/884122 - 2016 - Progress in the development of lysine methyltransferase SETD8 inhibitors
Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Rescigno, Donatella; Mai, Antonello; Castellano, Sabrina; Sbardella, Gianluca - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1680-1685 - issn: 1860-7179 - wos: WOS:000383579700002 (16) - scopus: 2-s2.0-84983335802 (17)

11573/931824 - 2016 - MC1568 inhibits HDAC6/8 activity and influenza A virus replication in lung epithelial cells: Role of Hsp90 acetylation
Panella, Simona; Marcocci, Maria Elena; Celestino, Ignacio; Valente, Sergio; Zwergel, Clemens; Li Puma, Domenica Donatella; Nencioni, Lucia; Mai, Antonello; Palamara, Anna Teresa; Simonetti, Giovanna - 01a Articolo in rivista
paper: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 2017-2031 - issn: 1756-8919 - wos: WOS:000386339500004 (30) - scopus: 2-s2.0-84994010342 (33)

11573/894534 - 2016 - Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features
Speranzini, Valentina; Rotili, Dante; Ciossani, Giuseppe; Pilotto, Simona; Marrocco, Biagina; Forgione, Mariantonietta; Lucidi, Alessia; Forneris, Federico; Mehdipour, Parinaz; Velankar, Sameer; Mai, Antonello; Mattevi, Andrea - 01a Articolo in rivista
paper: SCIENCE ADVANCES (Washington, DC : American Association for the Advancement of Science, 2015-) pp. - - issn: 2375-2548 - wos: WOS:000383734400025 (59) - scopus: 2-s2.0-85020596495 (60)

11573/870518 - 2016 - LSD1 inhibitors: a patent review (2010-2015)
Stazi, Giulia; Zwergel, Clemens; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 565-580 - issn: 1354-3776 - wos: WOS:000374900000003 (47) - scopus: 2-s2.0-84961644830 (48)

11573/1147226 - 2016 - The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery
Stunnenberg, Hendrik G.; Abrignani, Sergio; Adams, David; De Almeida, Melanie; Altucci, Lucia; Amin, Viren; Amit, Ido; Antonarakis, Stylianos E.; Aparicio, Samuel; Arima, Takahiro; Arrigoni, Laura; Arts, Rob; Asnafi, Vahid; Badosa, Manel Esteller; Bae, Jae-Bum; Bassler, Kevin; Beck, Stephan; Berkman, Benjamin; Bernstein, Bradley E.; Bilenky, Mikhail; Bird, Adrian; Bock, Christoph; Boehm, Bernhard; Bourque, Guillaume; Breeze, Charles E.; Brors, Benedikt; Bujold, David; Burren, Oliver; Bussemakers, Marion J.; Butterworth, Adam; Campo, Elias; Carrillo-De-Santa-Pau, Enrique; Chadwick, Lisa; Chan, Kui Ming; Chen, Wei; Cheung, Tom H.; Chiapperino, Luca; Choi, Nak Hyen; Chung, Ho-Ryun; Clarke, Laura; Connors, Joseph M.; Cronet, Philippe; Danesh, John; Dermitzakis, Manolis; Drewes, Gerard; Durek, Pawel; Dyke, Stephanie; Dylag, Tomasz; Eaves, Connie J.; Ebert, Peter; Eils, Roland; Eils, Jürgen; Ennis, Catherine A.; Enver, Tariq; Feingold, Elise A.; Felder, Bärbel; Ferguson-Smith, Anne; Fitzgibbon, Jude; Flicek, Paul; Foo, Roger S. -Y.; Fraser, Peter; Frontini, Mattia; Furlong, Eileen; Gakkhar, Sitanshu; Gasparoni, Nina; Gasparoni, Gilles; Geschwind, Daniel H.; Glažar, Petar; Graf, Thomas; Grosveld, Frank; Guan, Xin-Yuan; Guigo, Roderic; Gut, Ivo G.; Hamann, Alf; Han, Bok-Ghee; Harris, R. Alan; Heath, Simon; Helin, Kristian; Hengstler, Jan G.; Heravi-Moussavi, Alireza; Herrup, Karl; Hill, Steven; Hilton, Jason A.; Hitz, Benjamin C.; Horsthemke, Bernhard; Hu, Ming; Hwang, Joo-Yeon; Ip, Nancy Y.; Ito, Takashi; Javierre, Biola-Maria; Jenko, Sasa; Jenuwein, Thomas; Joly, Yann; Jones, Steven J. M.; Kanai, Yae; Kang, Hee Gyung; Karsan, Aly; Kiemer, Alexandra K.; Kim, Song Cheol; Kim, Bong-Jo; Kim, Hyeon-Hoe; Kimura, Hiroshi; Kinkley, Sarah; Klironomos, Filippos; Koh, In-Uk; Kostadima, Myrto; Kressler, Christopher; Kreuzhuber, Roman; Kundaje, Anshul; Küppers, Ralf; Larabell, Carolyn; Lasko, Paul; Lathrop, Mark; Lee, Daniel H. S.; Lee, Suman; Lehrach, Hans; Leitão, Elsa; Lengauer, Thomas; Lernmark, Åke; Leslie, R. David; Leung, Gilberto K. K.; Leung, Danny; Loeffler, Markus; Ma, Yussanne; Mai, Antonello; Manke, Thomas; Marcotte, Eric R.; Marra, Marco A.; Martens, Joost H. A.; Martin-Subero, Jose Ignacio; Maschke, Karen; Merten, Christoph; Milosavljevic, Aleksandar; Minucci, Saverio; Mitsuyama, Totai; Moore, Richard A.; Müller, Fabian; Mungall, Andrew J.; Netea, Mihai G.; Nordström, Karl; Norstedt, Irene; Okae, Hiroaki; Onuchic, Vitor; Ouellette, Francis; Ouwehand, Willem; Pagani, Massimiliano; Pancaldi, Vera; Pap, Thomas; Pastinen, Tomi; Patel, Ronak; Paul, Dirk S.; Pazin, Michael J.; Pelicci, Pier Giuseppe; Phillips, Anthony G.; Polansky, Julia; Porse, Bo; Pospisilik, J. Andrew; Prabhakar, Shyam; Procaccini, Dena C.; Radbruch, Andreas; Rajewsky, Nikolaus; Rakyan, Vardham; Reik, Wolf; Ren, Bing; Richardson, David; Richter, Andreas; Rico, Daniel; Roberts, David J.; Rosenstiel, Philip; Rothstein, Mark; Salhab, Abdulrahman; Sasaki, Hiroyuki; Satterlee, John S.; Sauer, Sascha; Schacht, Claudia; Schmidt, Florian; Schmitz, Gerd; Schreiber, Stefan; Schröder, Christopher; Schübeler, Dirk; Schultze, Joachim L.; Schulyer, Ronald P.; Schulz, Marcel; Seifert, Martin; Shirahige, Katsuhiko; Siebert, Reiner; Sierocinski, Thomas; Siminoff, Laura; Sinha, Anupam; Soranzo, Nicole; Spicuglia, Salvatore; Spivakov, Mikhail; Steidl, Christian; Strattan, J. Seth; Stratton, Michael; Südbeck, Peter; Sun, Hao; Suzuki, Narumi; Suzuki, Yutaka; Tanay, Amos; Torrents, David; Tyson, Frederick L.; Ulas, Thomas; Ullrich, Sebastian; Ushijima, Toshikazu; Valencia, Alfonso; Vellenga, Edo; Vingron, Martin; Wallace, Chris; Wallner, Stefan; Walter, Jörn; Wang, Huating; Weber, Stephanie; Weiler, Nina; Weller, Andreas; Weng, Andrew; Wilder, Steven; Wiseman, Sam M.; Wu, Angela R.; Wu, Zhenguo; Xiong, Jieyi; Yamashita, Yasuhiro; Yang, Xinyi; Yap, Desmond Y.; Yip, Kevin Y.; Yip, Stephen; Yoo, Jae-Il; Zerbino, Daniel; Zipprich, Gideon; Hirst, Martin - 01a Articolo in rivista
paper: CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 1145-1149 - issn: 0092-8674 - wos: WOS:000389470100004 (272) - scopus: 2-s2.0-84995912090 (312)

11573/870523 - 2016 - 1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells
Valente, Sergio; Mellini, Paolo; Spallotta, Francesco; Carafa, Vincenzo; Nebbioso, Angela; Polletta, Lucia; Carnevale, Ilaria; Saladini, Serena; Trisciuoglio, Daniela; Gabellini, Chiara; Tardugno, Maria; Zwergel, Clemens; Cencioni, Chiara; Atlante, Sandra; Moniot, Sébastien; Steegborn, Clemens; Budriesi, Roberta; Tafani, Marco; Del Bufalo, Donatella; Altucci, Lucia; Gaetano, Carlo; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1471-1491 - issn: 0022-2623 - wos: WOS:000371103600016 (59) - scopus: 2-s2.0-84959335947 (63)

11573/884171 - 2016 - The histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases
Van Den Bosch, Thea; Boichenko, Alexander; Leus, Niek G. J.; Ourailidou, Maria E.; Wapenaar, Hannah; Rotili, Dante; Mai, Antonello; Imhof, Axel; Bischoff, Rainer; Haisma, Hidde J.; Dekker, Frank J. - 01a Articolo in rivista
paper: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited -London ; New York : Pergamon Press, 1958-) pp. 130-140 - issn: 0006-2952 - wos: WOS:000371446300011 (41) - scopus: 2-s2.0-84958753301 (51)

11573/856751 - 2016 - Discovery of a novel inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) as orally active antitumor agent
Vianello, Paola; Botrugno, Oronza A; Cappa, Anna; Dal Zuffo, Roberto; Dessanti, Paola; Mai, Antonello; Marrocco, Biagina; Mattevi, Andrea; Meroni, Giuseppe; Minucci, Saverio; Stazi, Giulia; Thaler, Florian; Trifiró, Paolo; Valente, Sergio; Villa, Manuela; Varasi, Mario; Mercurio, Ciro - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1501-1517 - issn: 0022-2623 - wos: WOS:000371103600018 (66) - scopus: 2-s2.0-84959421233 (68)

11573/870553 - 2016 - DNA methyltransferases Inhibitors from natural sources
Zwergel, Clemens; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: CURRENT TOPICS IN MEDICINAL CHEMISTRY (Hilversum : Bentham Science Publishers) pp. 680-696 - issn: 1568-0266 - wos: WOS:000364586000004 (50) - scopus: 2-s2.0-84983215072 (57)

11573/884227 - 2015 - Identification of structural features of 2-alkylidene-1,3-dicarbonyl derivatives that induce inhibition and/or activation of histone acetyltransferases KAT3B/p300 and KAT2B/PCAF
Castellano, Sabrina; Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Mai, Antonello; Novellino, Ettore; Tosco, Alessandra; Sbardella, Gianluca - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 144-157 - issn: 1860-7179 - wos: WOS:000346766700014 (18) - scopus: 2-s2.0-84919779703 (22)

11573/884213 - 2015 - Sirtuin function in aging heart and vessels
Cencioni, Chiara; Spallotta, Francesco; Mai, Antonello; Martelli, Fabio; Farsetti, Antonella; Zeiher, Andreas M.; Gaetano, Carlo - 01a Articolo in rivista
paper: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 55-61 - issn: 0022-2828 - wos: WOS:000356839100007 (75) - scopus: 2-s2.0-84937970546 (81)

11573/884205 - 2015 - A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts
De Luca, Anastasia; Rotili, Dante; Carpanese, Debora; Lenoci, Alessia; Calderan, Laura; Scimeca, Manuel; Mai, Antonello; Bonanno, Elena; Rosato, Antonio; Geroni, Cristina; Quintieri, Luigi; Caccuri, Anna Maria - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 4126-4143 - issn: 1949-2553 - wos: WOS:000352696200052 (26) - scopus: 2-s2.0-84924251939 (27)

11573/884185 - 2015 - Chronic stress and antidepressant induced changes in Hdac5 and Sirt2 affect synaptic plasticity
Erburu, M.; Muñoz Cobo, I.; Domínguez Andrés, J.; Beltran, E.; Suzuki, T.; Mai, Antonello; Valente, Sergio; Puerta, E.; Tordera, R. M. - 01a Articolo in rivista
paper: EUROPEAN NEUROPSYCHOPHARMACOLOGY (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 2036-2048 - issn: 0924-977X - wos: WOS:000369152500020 (53) - scopus: 2-s2.0-84947494371 (56)

11573/784167 - 2015 - Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells
G., Di Pompo; M., Salerno; Rotili, Dante; Valente, Sergio; Zwergel, Clemens; S., Avnet; G., Lattanzi; N., Baldini; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4073-4079 - issn: 0022-2623 - wos: WOS:000354911200031 (55) - scopus: 2-s2.0-84929378676 (56)

11573/884194 - 2015 - A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib
Graziani, Grazia; Artuso, Simona; De Luca, Anastasia; Muzi, Alessia; Rotili, Dante; Scimeca, Manuel; Atzori, Maria Grazia; Ceci, Claudia; Mai, Antonello; Leonetti, Carlo; Levati, Lauretta; Bonanno, Elena; Tentori, Lucio; Caccuri, Anna Maria - 01a Articolo in rivista
paper: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited -London ; New York : Pergamon Press, 1958-) pp. 16-27 - issn: 0006-2952 - wos: WOS:000353858800002 (30) - scopus: 2-s2.0-84930886228 (31)

11573/884225 - 2015 - New insights on the mechanism of quinoline-based DNA methyltransferase inhibitors
Gros, Christina; Fleury, Laurence; Nahoum, Virginie; Faux, Céline; Valente, Sergio; Labella, Donatella; Cantagrel, Frédéric; Rilova, Elodie; Bouhlel, Mohamed Amine; David Cordonnier, Marie Hélène; Dufau, Isabelle; Ausseil, Frédéric; Mai, Antonello; Mourey, Lionel; Lacroix, Laurent; Arimondo, Paola B. - 01a Articolo in rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 6293-6302 - issn: 0021-9258 - wos: WOS:000350732500035 (47) - scopus: 2-s2.0-84924897991 (52)

11573/870559 - 2015 - Abstract 2946: Effects of two novel quinoline-based non-nucleoside DNA methyltransferase inhibitors against bone sarcomas
Manara, Maria Cristina; Valente, Sergio; Cristalli, Camilla; Baricordi, Cristina; Zwergel, Clemens; Arimondo, Paola B; Picci, Piero; Mai, Antonello; Scotlandi, Katia - 04d Abstract in atti di convegno
paper: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 2946-2946 - issn: 0008-5472 - wos: WOS:000371578506091 (0) - scopus: (0)

11573/884196 - 2015 - A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach
Milite, Ciro; Feoli, Alessandra; Sasaki, Kazuki; La Pietra, Valeria; Balzano, Amodio Luca; Marinelli, Luciana; Mai, Antonello; Novellino, Ettore; Castellano, Sabrina; Tosco, Alessandra; Sbardella, Gianluca - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2779-2798 - issn: 0022-2623 - wos: WOS:000351971800013 (44) - scopus: 2-s2.0-84925957014 (47)

11573/856754 - 2015 - Discovery of inhibitors for the ether lipid-generating enzyme AGPS as anti-cancer agents
Piano, Valentina; Benjamin, Daniel I.; Valente, Sergio; Nenci, Simone; Marrocco, Biagina; Mai, Antonello; Aliverti, Alessandro; Nomura, Daniel K; Mattevi, Andrea - 01a Articolo in rivista
paper: ACS CHEMICAL BIOLOGY (AMERICAN CHEMICAL SOCiety, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036) pp. 2589-2597 - issn: 1554-8929 - wos: WOS:000365462700020 (49) - scopus: 2-s2.0-84947909618 (49)

11573/789900 - 2015 - SIRT5 regulation of ammonia-induced autophagy and mitophagy
Polletta, Lucia; Vernucci, Enza; Carnevale, Ilaria; Arcangeli, Tania; Rotili, Dante; Palmerio, Silvia; Steegborn, Clemens; Nowak, Theresa; Schutkowski, Mike; Pellegrini, Laura; Sansone, Luigi; Villanova, Lidia; Runci, Alessandra; Pucci, Bruna; Morgante, Emanuela; Fini, Massimo; Mai, Antonello; Russo, Matteo A; Tafani, Marco - 01a Articolo in rivista
paper: AUTOPHAGY (Landes Bioscience Georgetown TX 78628) pp. 253-270 - issn: 1554-8627 - wos: WOS:000352778700007 (231) - scopus: 2-s2.0-84943265499 (236)

11573/680651 - 2015 - Synthesis and structure-activity relationship of new cytotoxic agents targeting human glutathione-S-transferases.
Rotili, Dante; De Luca, A; Tarantino, D; Pezzola, S; Forgione, Mariantonietta; Morozzo Della Rocca, B; Falconi, M; Mai, Antonello; Caccuri, A. M. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 156-171 - issn: 0223-5234 - wos: WOS:000348003500017 (32) - scopus: 2-s2.0-84908450815 (34)

11573/784164 - 2015 - Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation
S., Pilotto; V., Speranzini; M., Tortorici; D., Durand; A., Fish; Valente, Sergio; F., Forneris; Mai, Antonello; T. K., Sixma; P., Vachette; A., Mattevi - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 2752-2757 - issn: 0027-8424 - wos: WOS:000350224900048 (71) - scopus: 2-s2.0-84924368105 (74)

11573/781696 - 2015 - Pure diastereomers of a tranylcypromine-based LSD1 inhibitor: enzyme selectivity and in-cell studies
Valente, Sergio; Veronica, Rodriguez; Ciro, Mercurio; Paola, Vianello; Bruna, Saponara; Roberto, Cirilli; Giuseppe, Ciossani; Labella, Donatella; Marrocco, Biagina; Ruoppolo, Giovanni; Oronza A., Botrugno; Paola, Dessanti; Saverio, Minucci; Andrea, Mattevi; Mario, Varasi; Mai, Antonello - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 173-177 - issn: 1948-5875 - wos: WOS:000349652000012 (21) - scopus: 2-s2.0-84922867052 (18)

11573/781693 - 2015 - Pure enantiomers of benzoylamino-tranylcypromine: LSD1 inhibition, gene modulation in human leukemia cells and effects on clonogenic potential of murine promyelocytic blasts
Valente, Sergio; Veronica, Rodriguez; Mercurio, Ciro; Vianello, Paola; Saponara, Bruna; Cirilli, Roberto; Ciossani, Giuseppe; Labella, Donatella; Marrocco, Biagina; Monaldi, Daria; Ruoppolo, Giovanni; Tilset, Mats; Botrugno, Oronza A.; Dessanti, Paola; Minucci, Saverio; Mattevi, Andrea; Varasi, Mario; Mai, Antonello - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 163-174 - issn: 0223-5234 - wos: WOS:000353730900016 (27) - scopus: 2-s2.0-84924406877 (30)

11573/779609 - 2015 - Pyrrole- and indole-containing tranylcypromine derivatives as novel lysine-specific demethylase 1 inhibitors active on cancer cells.
Veronica, Rodriguez; Valente, Sergio; Stefano, Rovida; Rotili, Dante; Stazi, Giulia; Lucidi, Alessia; Giuseppe, Ciossani; Andrea, Mattevi; Oronza A., Botrugno; Paola, Dessanti; Ciro, Mercurio; Paola, Vianello; Saverio, Minucci; Mario, Varasi; Mai, Antonello - 01a Articolo in rivista
paper: MEDCHEMCOMM (Cambridge : Royal Society of Chemistry, 2010-) pp. 665-670 - issn: 2040-2503 - wos: WOS:000352903400023 (22) - scopus: 2-s2.0-84928004801 (24)

11573/884188 - 2015 - Targeting lysine deacetylases (KDACs) in parasites
Wang, Qi; Rosa, Bruce A.; Nare, Bakela; Powell, Kerrie; Valente, Sergio; Rotili, Dante; Mai, Antonello; Marshall, Garland R.; Mitreva, Makedonka - 01a Articolo in rivista
paper: PLOS NEGLECTED TROPICAL DISEASES (San Francisco, CA : Public Library of Science) pp. e000426- - issn: 1935-2727 - wos: WOS:000363031200020 (40) - scopus: 2-s2.0-84943193825 (43)

11573/884182 - 2015 - Enzyme kinetics and inhibition of histone acetyltransferase KAT8
Wapenaar, Hannah; Van Der Wouden, Petra E; Groves, Matthew R; Rotili, Dante; Mai, Antonello; Dekker, Frank J. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ([Paris] : Elsevier, [198?]-) pp. 289-296 - issn: 1768-3254 - wos: WOS:000364891400020 (28) - scopus: 2-s2.0-84945264596 (30)

11573/870535 - 2015 - Emerging approaches for histone deacetylase inhibitor drug discovery
Zwergel, Clemens; Valente, Sergio; Jacob, Claus; Mai, Antonello - 01a Articolo in rivista
paper: EXPERT OPINION ON DRUG DISCOVERY (--London United Kingdom:Informa Healthcare -London : Informa Healthcare, 2006-.) pp. 599-613 - issn: 1746-0441 - wos: WOS:000355006600004 (63) - scopus: 2-s2.0-84929928202 (70)

11573/557642 - 2014 - Reversible acetylation regulates vascular endothelial growth factor receptor-2 activity
A., Zecchin; L., Pattarini; M. I., Gutierrez; M., Mano; Mai, Antonello; Valente, Sergio; M. P., Myers; S., Pantano; M., Giacca - 01a Articolo in rivista
paper: JOURNAL OF MOLECULAR CELL BIOLOGY (Shanghai : Journal of Molecular Cell Biology Editorial Office Oxford University Press) pp. 116-127 - issn: 1674-2788 - wos: WOS:000336081100003 (30) - scopus: 2-s2.0-84899675551 (32)

11573/1155213 - 2014 - Sirtuins blunt reactive gliosis in an in vitro model of Alzheimer’s disease.
Bronzuoli, Maria Rosanna; Scuderi, Caterina; Stecca, Claudia; Rotili, Dante; Valente, Sergio; Cugno, Michele; Mai, Antonello; Steardo, Luca. - 04d Abstract in atti di convegno
conference: 17° Simposio SIF Dottorandi, Assegnisti di Ricerca Postdottorandi e Specializzandi in Farmacologia e Scienze Affini (Rimini)
book: 17° Simposio SIF Dottorandi, Assegnisti di Ricerca Postdottorandi e Specializzandi in Farmacologia e Scienze Affini. - ()

11573/665415 - 2014 - Novel inhibitors of human histone deacetylases: Design, synthesis and bioactivity of 3-alkenoylcoumarines
C., Seidel; M., Schnekenburger; Zwergel, Clemens; F., Gaascht; Mai, Antonello; M., Dicato; G., Kirsch; Valente, Sergio; M., Diederich - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 3797-3801 - issn: 0960-894X - wos: WOS:000340565900024 (43) - scopus: 2-s2.0-84905916821 (48)

11573/685071 - 2014 - Evaluation of a large library of (thiazol-2-yl)hydrazones and analogues as histone acetyltransferase inhibitors: Enzyme and cellular studies.
Carradori, S; Rotili, Dante; De Monte, Celeste; Lenoci, A; D'ascenzio, M; Rodriguez, V; Filetici, Patrizia; Miceli, M; Nebbioso, A; Altucci, L; Secci, Daniela; Mai, Antonello - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 569-578 - issn: 0223-5234 - wos: WOS:000337985400049 (49) - scopus: 2-s2.0-84900559630 (56)

11573/557645 - 2014 - Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS
Ciarapica, R.; Carcarino, E.; Adesso, L.; De Salvo, Maria; Bracaglia, G.; Leoncini, P. P.; Dall'agnese, A.; Verginelli, F.; Milano, G. M.; Boldrini, R.; Inserra, A.; Stifani, S.; Screpanti, Isabella; Marquez, V. E.; Valente, Sergio; Mai, Antonello; Puri, P. L.; Locatelli, F.; Palacios, D.; Rota, R. - 01a Articolo in rivista
paper: BMC CANCER (London: BioMed Central, [2001]-) pp. 139- - issn: 1471-2407 - wos: WOS:000332528100001 (51) - scopus: 2-s2.0-84898597003 (58)

11573/670458 - 2014 - The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx)
Ciarapica, R.; De Salvo, Maria; Carcarino, E.; Bracaglia, G.; Adesso, Laura; Leoncini, P. P.; Dall'agnese, A.; Walters, Z. S.; Verginelli, F.; De Sio, L.; Boldrini, R.; Inserra, A.; Bisogno, G.; Rosolen, A.; Alaggio, R.; Ferrari, A.; Collini, P.; Locatelli, M.; Stifani, S.; Screpanti, Isabella; Rutella, S.; Yu, Q.; Marquez, V. E.; Shipley, J.; Valente, Sergio; Mai, Antonello; Miele, L.; Puri, P. L.; Locatelli, F.; Palacios, D.; Rota, R. - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 4173-4184 - issn: 0950-9232 - wos: WOS:000340595700008 (56) - scopus: 2-s2.0-84905868284 (61)

11573/884235 - 2014 - Histone modifications, stem cells and prostate cancer
Crea, Francesco; Clermont, Pier Luc; Mai, Antonello; Helgason, Cheryl D. - 01a Articolo in rivista
paper: CURRENT PHARMACEUTICAL DESIGN (Hilversum : Bentham Science Publishers) pp. 1687-97- - issn: 1873-4286 - wos: WOS:000334311500012 (11) - scopus: 2-s2.0-84903744315 (11)

11573/556419 - 2014 - Context-Selective Death of Acute Myeloid Leukemia Cells Triggered by the Novel Hybrid Retinoid-HDAC Inhibitor MC2392.
De Bellis, F; Carafa, V; Conte, M; Rotili, Dante; Petraglia, F; Matarese, F; Françoijs, Kj; Ablain, J; Valente, Sergio; Castellano, R; Goubard, A; Collette, Y; Mandoli, A; Martens, Jh; De Thé, H; Nebbioso, A; Mai, Antonello; Stunnenberg, Hg; Altucci, L. - 01a Articolo in rivista
paper: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 2328-2339 - issn: 0008-5472 - wos: WOS:000334584200020 (28) - scopus: 2-s2.0-84899541163 (33)

11573/884228 - 2014 - Dissecting histone deacetylase role in pulmonary arterial smooth muscle cell proliferation and migration
Galletti, Margherita; Cantoni, Silvia; Zambelli, Filippo; Valente, Sabrina; Palazzini, Massimiliano; Manes, Alessandra; Pasquinelli, Gianandrea; Mai, Antonello; Galiè, Nazzareno; Ventura, Carlo - 01a Articolo in rivista
paper: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited -London ; New York : Pergamon Press, 1958-) pp. 181-190 - issn: 0006-2952 - wos: WOS:000341070800006 (25) - scopus: 2-s2.0-84906791178 (27)

11573/664054 - 2014 - PRMT1 arginine methyltransferase accumulates in cytoplasmic bodies that respond to selective inhibition and DNA damage
J., Suchánková; S., Legartová; P., Sehnalová; S., Kozubek; Valente, Sergio; Labella, Donatella; Mai, Antonello; C., Eckerich; F. O., Fackelmayer; D. V., Sorokin; E., Bártová - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF HISTOCHEMISTRY (Pavia : PagePress Publications, 2010) pp. 139-151 - issn: 2038-8306 - wos: WOS:000338624700013 (10) - scopus: 2-s2.0-84899705373 (9)

11573/556417 - 2014 - Quinoline-based p300 histone acetyltransferase inhibitors with pro-apoptotic activity in human leukemia U937 cells.
Lenoci, Alessia; Tomassi, S; Conte, M; Benedetti, R; Rodriguez, V; Carradori, Simone; Secci, Daniela; Castellano, S; Sbardella, G; Filetici, P; Novellino, E; Altucci, L; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 542-548 - issn: 1860-7187 - wos: WOS:000331795500010 (26) - scopus: 2-s2.0-84896698147 (27)

11573/1147222 - 2014 - Targeting epigenetics in drug discovery
Mai, Antonello - 01m Editorial/Introduzione in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 415-417 - issn: 1860-7179 - wos: (0) - scopus: 2-s2.0-84896725631 (12)

11573/665613 - 2014 - Sirtuin modulators: an updated patent review (2012 - 2014)
P., Mellini; Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 5-15 - issn: 1354-3776 - wos: WOS:000346742700002 (48) - scopus: 2-s2.0-84919458504 (50)

11573/665612 - 2014 - Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: A novel class of irreversible inhibitors of histone demethylase KDM1A
P., Vianello; O. A., Botrugno; A., Cappa; G., Ciossani; P., Dessanti; Mai, Antonello; A., Mattevi; G., Meroni; S., Minucci; F., Thaler; M., Tortorici; P., Trifiró; Valente, Sergio; M., Villa; M., Varasi; C., Mercurio - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 352-363 - issn: 0223-5234 - wos: WOS:000343781800032 (49) - scopus: 2-s2.0-84906839626 (48)

11573/542432 - 2014 - Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities
Rotili, Dante; Stefano, Tomassi; Mariarosaria, Conte; Rosaria, Benedetti; Marcello, Tortorici; Giuseppe, Ciossani; Valente, Sergio; Marrocco, Biagina; Labella, Donatella; Ettore, Novellino; Andrea, Mattevi; Lucia, Altucci; Tumber, Anthony; Yapp, Clarence; N. F., King Oliver; Richard J., Hopkinson; Akane, Kawamura; J., Schofield Christopher; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 42-55 - issn: 0022-2623 - wos: WOS:000329677800004 (96) - scopus: 2-s2.0-84892565144 (105)

11573/681257 - 2014 - Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity.
Rotili, Dante; Tarantino, D; Marrocco, Biagina; Gros, C; Masson, V; Poughon, V; Ausseil, F; Chang, Y; Labella, D; Cosconati, S; Di Maro, S; Novellino, E; Schnekenburger, M; Grandjenette, C; Bouvy, C; Diederich, M; Cheng, X; Arimondo, Pb; Mai, Antonello - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. - - issn: 1932-6203 - wos: WOS:000338213300096 (32) - scopus: 2-s2.0-84901487126 (35)

11573/681252 - 2014 - Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes
Rotili, Dante; Tarantino, D; Nawrozkij, Mb; Babushkin, As; Botta, G; Marrocco, Biagina; Cirilli, R; Menta, Sergio; Badia, R; Crespan, E; Ballante, Flavio; Ragno, Rino; Esté, Ja; Maga, G; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5212-5225 - issn: 0022-2623 - wos: WOS:000338184100018 (18) - scopus: 2-s2.0-84903515653 (18)

11573/643824 - 2014 - Sirtuin modulators control reactive gliosis in an in vitro model of alzheimer's disease
Scuderi, Caterina; Stecca, Claudia; Bronzuoli, Maria Rosanna; Rotili, Dante; Valente, Sergio; Mai, Antonello; Steardo, Luca - 01a Articolo in rivista
paper: FRONTIERS IN PHARMACOLOGY (Lausanne: Frontiers Media S.A., 2010-) pp. - - issn: 1663-9812 - wos: WOS:000347086800001 (52) - scopus: 2-s2.0-84904631078 (56)

11573/553541 - 2014 - I kappa B kinase (IKK)-epsilon targets interferon regulatory factor 1 in activated T lymphocytes.
Sgarbanti, M; Marsili, G; Remoli, Al; Stellacci, E; Mai, Antonello; Rotili, Dante; Perrotti, E; Acchioni, C; Orsatti, R; Iraci, N; Ferrari, M; Borsetti, A; Hiscott, J; Battistini, A. - 01a Articolo in rivista
paper: MOLECULAR AND CELLULAR BIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 1054-1065 - issn: 0270-7306 - wos: WOS:000331995800012 (28) - scopus: 2-s2.0-84894284462 (30)

11573/664060 - 2014 - 1,3,4-Oxadiazole-Containing Histone Deacetylase Inhibitors: Anticancer Activities in Cancer Cells
Valente, Sergio; D., Trisciuoglio; T., De Luca; A., Nebbioso; Labella, Donatella; Lenoci, Alessia; C., Bigogno; G. M., Dondio; M., Miceli; G., Brosch; D., Del Bufalo; L., Altucci; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6259-6265 - issn: 0022-2623 - wos: WOS:000339540800033 (124) - scopus: 2-s2.0-84904962606 (127)

11573/664047 - 2014 - Small-molecule inhibitors of histone deacetylase for the treatment of cancer and non-cancer diseases: a patent review (2011 - 2013).
Valente, Sergio; Mai, Antonello - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 401-415 - issn: 1354-3776 - wos: WOS:000333098200003 (45) - scopus: 2-s2.0-84896470334 (45)

11573/547528 - 2014 - Selective Non-nucleoside Inhibitors of Human DNA Methyltransferases Active in Cancer Including in Cancer Stem Cells
Valente, Sergio; Yiwei, Liu; Michael, Schnekenburger; Zwergel, Clemens; Sandro, Cosconati; Christina, Gros; Maria, Tardugno; Donatella, Labella; Cristina, Florean; Steven, Minden; Hideharu, Hashimoto; Yanqi, Chang; Xing, Zhang; Gilbert, Kirsch; Ettore, Novellino; Paola B., Arimondo; Miele, Evelina; Ferretti, Elisabetta; Gulino, Alberto; Marc, Diederich; Xiaodong, Cheng; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 701-713 - issn: 0022-2623 - wos: WOS:000331493000013 (107) - scopus: 2-s2.0-84894065301 (116)

11573/884229 - 2014 - Identification of NuRSERY, a new functional HDAC complex composed by HDAC5, GATA1, EKLF and pERK present in human erythroid cells
Varricchio, Lilian; Dell'aversana, Carmela; Nebbioso, Angela; Migliaccio, Giovanni; Altucci, Lucia; Mai, Antonello; Grazzini, Giuliano; Bieker, James J.; Migliaccio, Anna Rita - 01a Articolo in rivista
paper: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 112-122 - issn: 1357-2725 - wos: WOS:000335611500016 (25) - scopus: 2-s2.0-84896531605 (31)

11573/884231 - 2014 - The histone acetylase activator pentadecylidenemalonate 1b rescues proliferation and differentiation in the human cardiac mesenchymal cells of type 2 diabetic patients
Vecellio, Matteo; Spallotta, Francesco; Nanni, Simona; Colussi, Claudia; Cencioni, Chiara; Derlet, Anja; Bassetti, Beatrice; Tilenni, Manuela; Carena, Maria Cristina; Farsetti, Antonella; Sbardella, Gianluca; Castellano, Sabrina; Mai, Antonello; Martelli, Fabio; Pompilio, Giulio; Capogrossi, Maurizio C.; Rossini, Alessandra; Dimmeler, Stefanie; Zeiher, Andreas; Gaetano, Carlo - 01a Articolo in rivista
paper: DIABETES (American Diabetes Association:National Service Center, 1701 North Beaureguard Street:Alexandria, VA 22311:(800)232-3472, (703)549-1500, INTERNET: http://www.diabetes.org/diabetscare, Fax: (703)549-6995) pp. 2132-2147 - issn: 0012-1797 - wos: WOS:000336643900037 (60) - scopus: 2-s2.0-84899824083 (63)

11573/513469 - 2013 - A Nitric Oxide-dependent crosstalk between class I and III Histone Deacetylases accelerates skin repair.
2. Spallotta, F.; Cencioni, C.; Straino, S.; Nanni, S.; Rosati, J.; Artuso, S.; Manni, I.; Colussi, C.; Piaggio, G.; Martelli, F.; Valente, Sergio; Mai, Antonello; Capogrossi, M. C.; Farsetti, A.; Gaetano, C. - 01a Articolo in rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 11004-11012 - issn: 0021-9258 - wos: WOS:000317915500007 (66) - scopus: 2-s2.0-84876580701 (72)

11573/525990 - 2013 - Oxidative stress and epigenetic regulation in ageing and age-related diseases
Chiara, Cencioni; Spallotta, Francesco; Fabio, Martelli; Valente, Sergio; Mai, Antonello; Zeiher Am, Gaetano C. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 17643-17663 - issn: 1661-6596 - wos: WOS:000328623900021 (154) - scopus: 2-s2.0-84883479431 (180)

11573/513467 - 2013 - Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue.
Galmozzi, A.; Mitro, N.; Ferrari, A.; Gers, E.; Gilardi, F.; Godio, C.; Cermenati, G.; Gualerzi, A.; Donetti, E.; Rotili, Dante; Valente, Sergio; Guerrini, U.; Caruso, D.; Mai, Antonello; Saez, E.; De Fabiani, E.; Crestani, M. - 01a Articolo in rivista
paper: DIABETES (American Diabetes Association:National Service Center, 1701 North Beaureguard Street:Alexandria, VA 22311:(800)232-3472, (703)549-1500, INTERNET: http://www.diabetes.org/diabetscare, Fax: (703)549-6995) pp. 732-742 - issn: 0012-1797 - wos: WOS:000315556400017 (187) - scopus: 2-s2.0-84869106554 (203)

11573/513468 - 2013 - Class II HDAC Inhibition Hampers Hepatic Stellate Cell Activation by Induction of MicroRNA-29
Inge, Mannaerts; Nathalie, Eysackers; Oscar O., Onyema; Katrien Van, Beneden; Valente, Sergio; Mai, Antonello; Margarete, Odenthal; Leo A., Van Grunsven - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e55786- - issn: 1932-6203 - wos: WOS:000314610600159 (62) - scopus: 2-s2.0-84873122711 (68)

11573/884236 - 2013 - Screen of pseudopeptidic inhibitors of human sirtuins 1-3: Two lead compounds with antiproliferative effects in cancer cells
Mellini, Paolo; Kokkola, Tarja; Suuronen, Tiina; Salo, Heikki S.; Tolvanen, Laura; Mai, Antonello; Lahtela Kakkonen, Maija; Jarho, Elina M. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6681-6695 - issn: 0022-2623 - wos: WOS:000330097400013 (30) - scopus: 2-s2.0-84884225041 (33)

11573/525042 - 2013 - Detrimental effect of class-selective histone deacetylase inhibitors during tissue regeneration following hindlimb ischemia
Spallotta, F.; Silvia, Tardivo; Nanni, S.; Rosati, J. D.; Straino, S.; Mai, Antonello; Vecellio, M.; Valente, Sergio; Capogrossi, M. C.; Farsetti, A.; Martone, Julie; Bozzoni, Irene; Pontecorvi, A.; Gaetano, C.; Colussi, C. - 01a Articolo in rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 22915-22929 - issn: 0021-9258 - wos: WOS:000330598200004 (27) - scopus: 2-s2.0-84881396773 (26)

11573/884239 - 2013 - Protein recognition by short peptide reversible inhibitors of the chromatin-modifying LSD1/CoREST lysine demethylase
Tortorici, Marcello; Borrello, Maria Teresa; Tardugno, Maria; Chiarelli, Laurent R.; Pilotto, Simona; Ciossani, Giuseppe; Vellore, Nadeem A.; Bailey, Sarah G.; Cowan, Jonathan; O'connell, Maria; Crabb, Simon J.; Packham, Graham; Mai, Antonello; Baron, Riccardo; Ganesan, A.; Mattevi, Andrea - 01a Articolo in rivista
paper: ACS CHEMICAL BIOLOGY (AMERICAN CHEMICAL SOCiety, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036) pp. 1677-1682 - issn: 1554-8929 - wos: WOS:000323363000004 (59) - scopus: 2-s2.0-84880777273 (61)

11573/514588 - 2013 - tert-Butylcarbamate-Containing Histone Deacetylase Inhibitors: Apoptosis Induction, Cytodifferentiation, and Antiproliferative Activities in Cancer Cells.
Valente, Sergio; Trisciuoglio, D; Tardugno, M; Benedetti, R; Labella, Donatella; Secci, Daniela; Mercurio, C; Boggio, R; Tomassi, S; Di Maro, S; Novellino, E; Altucci, L; Del Bufalo, D; Mai, Antonello; Cosconati, S. - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. - - issn: 1860-7179 - wos: WOS:000318245300013 (16) - scopus: 2-s2.0-84877064105 (18)

11573/525043 - 2013 - Reactivity of 4-vinyl-2H-1-benzopyran-2-ones in diels-alder cycloaddition reactions: Access to coumarin-based polycycles with Cdc25 phosphatase-inhibiting activity
Valente, Sergio; Zhanjie, Xu; Emilie, Bana; Zwergel, Clemens; Mai, Antonello; Jacob, Claus; Peter, Meiser; Denyse, Bagrel; Artur M. S., Silva; Kirsch, Gilbert - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 2869-2877 - issn: 1434-193X - wos: WOS:000318803200018 (11) - scopus: 2-s2.0-84877688906 (12)

11573/870542 - 2013 - Novel benzofuran-chromone and -coumarin derivatives: Synthesis and biological activity in K562 human leukemia cells
Zwergel, Clemens; Valente, Sergio; Salvato, Angela; Xu, Zhanjie; Talhi, Oualid; Mai, Antonello; Silva, Artur; Altucci, Lucia; Kirsch, Gilbert - 01a Articolo in rivista
paper: MEDCHEMCOMM (Cambridge : Royal Society of Chemistry, 2010-) pp. 1571-1579 - issn: 2040-2503 - wos: WOS:000327461300005 (47) - scopus: 2-s2.0-84888154287 (51)

11573/442878 - 2012 - An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases
Anup K., Upadhyay; Rotili, Dante; Ji Woong, Han; Ruogu, Hu; Yanqi, Chang; Donatella, Labella; Xing, Zhang; Young Sup, Yoon; Mai, Antonello; Xiaodong, Cheng - 01a Articolo in rivista
paper: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, -London; New York: Academic Press.) pp. 319-327 - issn: 0022-2836 - wos: WOS:000301313600001 (44) - scopus: 2-s2.0-84862777760 (47)

11573/513465 - 2012 - Identification of Small-Molecule Enhancers of Arginine Methylation Catalyzed by Coactivator-Associated Arginine Methyltransferase 1.
Castellano, S.; Spannhoff, A.; Milite, C.; Dal Piaz, F.; Cheng, D.; Tosco, A.; Viviano, M.; Yamani, A.; Cianciulli, A.; Sala, M.; Cura, V.; Cavarelli, J.; Novellino, E.; Mai, Antonello; Bedford, M. T.; Sbardella, G. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9875-9890 - issn: 0022-2623 - wos: WOS:000311461500040 (25) - scopus: 2-s2.0-84869995779 (27)

11573/485037 - 2012 - P300/CBP associated factor regulates nitroglycerin-dependent arterial relaxation by nε-lysine acetylation of contractile proteins
Colussi, C.; Scopece, A.; Vitale, S.; Spallotta, F.; Mattiussi, S.; Rosati, J.; Illi, B.; Mai, Antonello; Castellano, S.; Sbardella, Gianluca; Farsetti, A.; C, Gaetano; Mc, Capogrossi - 01a Articolo in rivista
paper: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY (-PHILADELPHIA, USA: LIPPINCOTT WILLIAMS & WILKINS -Dallas, TX : The Association, c1995-) pp. 2435-2443 - issn: 1079-5642 - wos: WOS:000308811200013 (28) - scopus: 2-s2.0-84866630451 (28)

11573/485018 - 2012 - BLUEPRINT to decode the epigenetic signature written in blood.
David, Adams; Lucia, Altucci; Stylianos E., Antonarakis; Ballesteros, Juan; Beck, Stephan; Bird, Adrian; Christoph, Bock; Bernhard, Boehm; Elias, Campo; Andrea, Caricasole; Fredrik, Dahl; Emmanouil T., Dermitzakis; Tariq, Enver; Manel, Esteller; Estivill, Xavier; Anne Ferguson, Smith; Fitzgibbon, Jude; Flicek, Paul; Claudia, Giehl; Thomas, Graf; Frank, Grosveld; Roderic, Guigo; Ivo, Gut; Kristian, Helin; Jarvius, Jonas; Ralf, Kuppers; Lehrach, Hans; Thomas, Lengauer; Åke, Lernmark; David Leslie Markus, Loeffler; Elizabeth, Macintyre; Mai, Antonello; Joost H. A., Martens; Saverio, Minucci; H., Ouwehand Willem; Pier Giuseppe, Pelicci; Helene, Pendeville; Porse, Bo; Vardhman, Rakyan; Reik, Wolf; Schrappe, Martin; Dirk, Schubeler; Seifert, Martin; Siebert, Reiner; David, Simmons; Nicole, Soranzo; Salvatore, Spicuglia; Michael, Stratton; Hendrik G., Stunnenberg; Amos, Tanay; David, Torrents; Alfonso, Valencia; Vellenga, Edo; Jorn Walter Martin, Vingron; Spike, Willcocks - 01a Articolo in rivista
paper: NATURE BIOTECHNOLOGY (New York, NY : Nature Pub. Co., [1996-) pp. 224-226 - issn: 1087-0156 - wos: WOS:000301303800012 (232) - scopus: 2-s2.0-84857980747 (260)

11573/513462 - 2012 - The emerging role of histone lysine demethylases in prostate cancer
Francesco, Crea; Lei, Sun; Mai, Antonello; Y. T., Chiang; William L., Farrar; Romano, Danesi; Cheryl D., Helgason - 01a Articolo in rivista
paper: MOLECULAR CANCER (London: BioMed Central-Springer) pp. 52-52 - issn: 1476-4598 - wos: WOS:000308750200001 (66) - scopus: 2-s2.0-84864510460 (76)

11573/884285 - 2012 - Screening assays for epigenetic targets using native histones as substrates
Hauser, Alexander Thomas; Bissinger, Elisabeth Maria; Metzger, Eric; Repenning, Antje; Bauer, Uta Maria; Mai, Antonello; Schüle, Roland; Jung, Manfred - 01a Articolo in rivista
paper: JOURNAL OF BIOMOLECULAR SCREENING (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 18-26 - issn: 1087-0571 - wos: WOS:000298886900003 (16) - scopus: 2-s2.0-84857326796 (18)

11573/485036 - 2012 - Amino acid starvation induces reactivation of silenced transgenes and latent HIV-1 provirus via down-regulation of histone deacetylase 4 (HDAC4)
I., Palmisano; G., Della Chiara; R. L., D'ambrosio; C., Huichalaf; P., Brambilla; S., Corbetta; M., Riba; R., Piccirillo; Valente, Sergio; G., Casari; Mai, Antonello; F., Martinelli Boneschi; D., Gabellini; G., Poli; M. V., Schiaffino - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. E2284-E2293 - issn: 0027-8424 - wos: WOS:000308085200011 (32) - scopus: 2-s2.0-84865194183 (35)

11573/485021 - 2012 - Highlights of the Keystone Symposium: sirtuins in metabolism, aging and disease
Michele M., Maxwell; Julien Francisco Zaldivar, Jolissaint; Mai, Antonello; Tiago F., Outeiro; Aleksey G., Kazanstev - 01a Articolo in rivista
paper: EMBO MOLECULAR MEDICINE (Chichester : Wiley-Blackwell, 2009-) pp. 557-560 - issn: 1757-4676 - wos: WOS:000305943600005 (4) - scopus: 2-s2.0-84863480943 (3)

11573/895421 - 2012 - 6-(Arylmethyl)pyrimidin-4(3H)-ones: Anthology and prospects of highly efficient anti-HIV agents
Novakov, I. A.; Artico, M.; Mai, Antonello; Rotili, Dante; Orlinson, B. S.; Brunilina, L. L.; Nawrozkij, M. B. - 01a Articolo in rivista
paper: RUSSIAN CHEMICAL BULLETIN (- New York : SPRINGER -New York : Consultants Bureau, c1993-) pp. 1399-1418 - issn: 1066-5285 - wos: WOS:000321771700009 (11) - scopus: 2-s2.0-84887395127 (11)

11573/495328 - 2012 - Carprofen Analogues as Sirtuin Inhibitors: Enzyme and Cellular Studies
Paolo, Mellini; Vincenzo, Carafa; Barbara Di, Rienzo; Rotili, Dante; De Vita, Daniela; Roberto, Cirilli; Bruno, Gallinella; Donatella Paola, Provvisiero; Salvatore Di, Maro; Ettore, Novellino; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1905-1908 - issn: 1860-7187 - wos: WOS:000310485200005 (14) - scopus: 2-s2.0-84868149996 (15)

11573/455654 - 2012 - 2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies.
Rotili, Dante; A., Samuele; Domenico, Tarantino; Ragno, Rino; Musmuca, Ira; Ballante, Flavio; G., Botta; Morera, Ludovica; Pierini, Marco; R., Cirilli; M. B., Nawrozkij; E., Gonzalez; B., Clotet; Marino, Artico; J. A., Este; G., Maga; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 3558-3562 - issn: 1520-4804 - wos: WOS:000302591100058 (29) - scopus: 2-s2.0-84859804994 (31)

11573/485200 - 2012 - Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells.
Rotili, Dante; Tarantino, D; Carafa, V; Paolini, C; Schemies, J; Jung, M; Botta, G; Di Maro, S; Novellino, E; Steinkühler, C; De Maria, R; Gallinari, P; Altucci, L; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8193-8197 - issn: 0022-2623 - wos: WOS:000309153500023 (32) - scopus: 2-s2.0-84866849116 (35)

11573/759461 - 2012 - Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells.
Rotili, Dante; Tarantino, D; Nebbioso, A; Paolini, C; Huidobro, C; Lara, E; Mellini, P; Lenoci, Alessia; Pezzi, R; Botta, G; Lahtela Kakkonen, M; Poso, A; Steinkühler, C; Gallinari, P; De Maria, R; Fraga, M; Esteller, M; Altucci, L; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 10937-10947 - issn: 0022-2623 - wos: WOS:000312681100009 (81) - scopus: 2-s2.0-84871662210 (84)

11573/477299 - 2012 - Histone Deacetylase Inhibitors: Structure-Based Modeling and Isoform-Selectivity Prediction
Silvestri, Laura; Ballante, Flavio; Mai, Antonello; R., Marshall Garland; Ragno, Rino - 01a Articolo in rivista
paper: JOURNAL OF CHEMICAL INFORMATION AND MODELING (AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036) pp. 2215-2235 - issn: 1549-9596 - wos: WOS:000308254200031 (25) - scopus: 2-s2.0-84865466261 (24)

11573/513460 - 2012 - Developing novel non-hydroxamate histone deacetylase inhibitors: the chelidamic warhead.
Valente, Sergio; Conte, M.; Tardugno, M.; Nebbioso, A; Tinari, G.; Altucci, L.; Mai, Antonello - 01a Articolo in rivista
paper: MEDCHEMCOMM (Cambridge : Royal Society of Chemistry, 2010-) pp. 298-304 - issn: 2040-2503 - wos: WOS:000301966800004 (6) - scopus: 2-s2.0-84857707526 (7)

11573/455694 - 2012 - Identification of PR-SET7 and EZH2 selective inhibitors inducing cell death in human leukemia U937 cells
Valente, Sergio; Ilaria, Lepore; Carmela, Dell'aversa; Maria, Tardugno; Sabrina, Castellano; Gianluca, Sbardella; Stefano, Tomassi; Salvatore Di, Maro; Ettore, Novellino; Di Santo, Roberto; Costi, Roberta; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
paper: BIOCHIMIE (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 2308-2313 - issn: 0300-9084 - wos: WOS:000310929200011 (22) - scopus: 2-s2.0-84867395419 (26)

11573/485203 - 2012 - p300/CBP-associated factor selectively regulates the extinction of conditioned fear.
W., Wei; C. M., Coelho; X., Li; R., Marek; S., Yan; S., Anderson; D., Meyers; C., Mukherjee; G., Sbardella; S., Castellano; C., Milite; Rotili, Dante; Mai, Antonello; P. A., Cole; P., Sah; M. S., Kobor; T. W., Bredy - 01a Articolo in rivista
paper: THE JOURNAL OF NEUROSCIENCE (Baltimore MD: Society of Neuroscience) pp. 11930-11941 - issn: 0270-6474 - wos: WOS:000308213900003 (72) - scopus: 2-s2.0-84865472870 (77)

11573/391029 - 2011 - Sirtinol Treatment Reduces Inflammation in Human Dermal Microvascular Endothelial Cells
Angela, Orecchia; Claudia, Scarponi; Di Felice, Francesca; Cesarini, Elisa; Simona, Avitabile; Mai, Antonello; Mauro, Maria Luisa; Valentina, Sirri; Giovanna, Zambruno; Cristina, Albanesi; Camilloni, Giorgio; Cristina M., Failla - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e24307- - issn: 1932-6203 - wos: WOS:000294803200013 (61) - scopus: 2-s2.0-80052638751 (66)

11573/458436 - 2011 - EPIGENETIC MODULATION OF PGC-1a ACTIVITY BY GCN5 INHIBITORS: WO2010007085
Carradori, Simone; Secci, Daniela; Mai, Antonello - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 1651-1656 - issn: 1354-3776 - wos: WOS:000294966800007 (9) - scopus: 2-s2.0-80053007226 (9)

11573/380081 - 2011 - Nε-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart
Colussi, C; Rosati, J; Straino, S; Spallotta, F; Berni, R; Stilli, D; Rossi, S; Musso, E; Macchi, E; Mai, Antonello; Sbardella, G; Castellano, S; Chimenti, Cristina; Frustaci, Andrea; Nebbioso, A; Altucci, L; Capogrossi, Mc; Gaetano, C. - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (Editore National Academy of Sciences a Washington, DC) pp. 2795-2800 - issn: 1091-6490 - wos: WOS:000287377000035 (88) - scopus: 2-s2.0-79952613152 (89)

11573/414595 - 2011 - Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: Enzyme selectivity and cellular activity
Donghang, Cheng; Valente, Sergio; Sabrina, Castellano; Gianluca, Sbardella; Di Santo, Roberto; Costi, Roberta; Mark T., Bedford; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4928-4932 - issn: 0022-2623 - wos: WOS:000292479600049 (66) - scopus: 2-s2.0-79960191524 (72)

11573/443817 - 2011 - Application of 3 μm particle-based amylose-derived chiral stationary phases for the enantioseparation of potential histone deacetylase inhibitors.
Ferretti, R; Mai, Antonello; Gallinella, B; Zanitti, L; Valente, Sergio; Cirilli, R. - 01a Articolo in rivista
paper: JOURNAL OF CHROMATOGRAPHY A (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 8394-8398 - issn: 0021-9673 - wos: WOS:000297036000012 (19) - scopus: 2-s2.0-80054874258 (19)

11573/442881 - 2011 - Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors
Gianluca, Sbardella; Mai, Antonello; Sara, Bartolini; Sabrina, Castellano; Roberto, Cirilli; Rotili, Dante; Ciro, Milite; Marisabella, Santoriello; Serena, Orlando; Ilaria, Sciamanna; Annalucia, Serafino; Patrizia, Lavia; Corrado, Spadafora - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5927-5936 - issn: 0022-2623 - wos: WOS:000294077300023 (12) - scopus: 2-s2.0-80051873043 (14)

11573/884287 - 2011 - Specific control of pancreatic endocrine β- and δ-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9
Lenoir, Olivia; Flosseau, Kathleen; Ma, Feng Xia; Blondeau, Bertrand; Mai, Antonello; Bassel Duby, Rhonda; Ravassard, Philippe; Olson, Eric N.; Haumaitre, Cécile; Scharfmann, Raphaël - 01a Articolo in rivista
paper: DIABETES (American Diabetes Association:National Service Center, 1701 North Beaureguard Street:Alexandria, VA 22311:(800)232-3472, (703)549-1500, INTERNET: http://www.diabetes.org/diabetscare, Fax: (703)549-6995) pp. 2861-2871 - issn: 0012-1797 - wos: WOS:000296954600025 (112) - scopus: 2-s2.0-80755168896 (122)

11573/1147220 - 2011 - Identification of specific and semi-specific SIRT inhibitors through computer-aided studies
Mai, Antonello - 01m Editorial/Introduzione in rivista
paper: AGING (Impact Journals LLC) pp. 819-820 - issn: 1945-4589 - wos: WOS:000296798400002 (1) - scopus: 2-s2.0-84864021601 (1)

11573/884294 - 2011 - Hydroxamic acids: Biological properties and potential uses as therapeutic agents
Mai, Antonello - 02a Capitolo o Articolo
book: PATAI - The chemistry of hydroxylamines, oximes and hydroxamic acids - ()

11573/378540 - 2011 - Gold drug auranofin restricts the viral reservoir in the monkey AIDS model and induces containment of viral load following ART suspension
Mark G., Lewis; Sandrina, Dafonseca; N., Chamont; Nicolas, Chomont; Palamara, Anna Teresa; Tardugno, Maria; Mai, Antonello; Matt, Collins; Wendeline L., Wagner; Jake Yalley, Ogunro; Jack, Greenhouse; Barbara, Chirullo; Sandro, Norelli; Enrico, Garaci; Andrea, Savarino - 01a Articolo in rivista
paper: AIDS (- Wolters Kluwer Health, Inc. -London : Lippincott Williams & Wilkins -London : Gower Academic Journals, 1987-) pp. 1347-1356 - issn: 0269-9370 - wos: WOS:000292183900001 (73) - scopus: 2-s2.0-79960014190 (78)

11573/442885 - 2011 - Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3'-C-methyladenosine in leukaemia cells.
Meli, M; Tolomeo, M; Grifantini, M; Mai, Antonello; Cappellacci, L; Petrelli, R; Rotili, Dante; Ferro, A; Saiko, P; Szekeres, T; Dusonchet, L. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF ONCOLOGY (National Hellenic Research Foundation:48 Vas Constatinou Avenue, Athens 11635 Greece:011 30 1 7241505, Fax: 011 30 1 7241505Editore attuale:PROFESSOR D A SPANDIDOS, 1, S MERKOURI ST, EDITORIAL OFFICE,, ATHENS, GREECE, 116 35. Editore precedente:Editorial Academy of the International Journal of Oncology.) pp. - - issn: 1019-6439 - wos: WOS:000289815800026 (9) - scopus: 2-s2.0-79954993415 (9)

11573/379234 - 2011 - Modulation of the activity of histone acetyltransferases by long chain alkylidenemalonates (LoCAMs)
Milite, C; Castellano, S; Benedetti, R; Tosco, A; Ciliberti, C; Vicidomini, C; Boully, L; Franci, G; Altucci, L; Mai, Antonello; Sbardella, G. - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 3690-3701 - issn: 0968-0896 - wos: WOS:000291477600010 (28) - scopus: 2-s2.0-79958265044 (29)

11573/379664 - 2011 - Biological Effects of MC2050, a Quinazoline-Based PARP-1 Inhibitor, in Human Neuroblastoma and EBV-Positive Burkitt's Lymphoma Cells
Mosca, Luciana; Rotili, Dante; Tempera, Italo; Masci, Alessandra; Fontana, Mario; Chiaraluce, Roberta; Mastromarino, Paola; D'erme, Maria; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 606-611 - issn: 1860-7179 - wos: WOS:000288814900006 (12) - scopus: 2-s2.0-79953056639 (11)

11573/418879 - 2011 - Identification of Small-Molecule Inhibitors of the XendoU Endoribonucleases Family
Ragno, Rino; Gioia, Ubaldo; Pietro, Laneve; Bozzoni, Irene; Mai, Antonello; Elisa, Caffarelli - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1797-1805 - issn: 1860-7179 - wos: WOS:000296417000007 (8) - scopus: 2-s2.0-80053427016 (9)

11573/442676 - 2011 - Photoactivable peptides for identifying enzyme-substrate and protein-protein interactions.
Rotili, Dante; Altun, M; Hamed, Rb; Loenarz, C; Thalhammer, A; Hopkinson, Rj; Tian, Ym; Ratcliffe, Pj; Mai, Antonello; Kessler, Bm; Schofield, C. J. - 01a Articolo in rivista
paper: CHEMICAL COMMUNICATIONS (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 1488-1490 - issn: 1359-7345 - wos: WOS:000286389500026 (5) - scopus: 2-s2.0-78751521073 (5)

11573/442886 - 2011 - Targeting histone demethylases: A new avenue for the fight against cancer
Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
paper: GENES & CANCER (Thousand Oaks, CA: SAGE Publications) pp. 663-679 - issn: 1947-6019 - wos: (0) - scopus: 2-s2.0-80054787805 (177)

11573/442882 - 2011 - A Photoreactive Small-Molecule Probe for 2-Oxoglutarate Oxygenases
Rotili, Dante; Mikael, Altun; Akane, Kawamura; Alexander, Wolf; Roman, Fischer; I. K., Leung; Mukram M, Mackeen; Ya Min, Tian; Peter J, Ratcliffe; Mai, Antonello; Benedikt M, Kessler; Christopher J, Schofield - 01a Articolo in rivista
paper: CHEMISTRY & BIOLOGY (Current Science:400 Market Street, Suite 700:Philadelphia, PA 19106:(800)427-1796, (215)574-2266, EMAIL: info@phl.cursci.com, INTERNET: http://www-current-science-group.com, Fax: (215)574-2225) pp. 642-654 - issn: 1074-5521 - wos: WOS:000291499600013 (43) - scopus: 2-s2.0-79957487715 (45)

11573/379781 - 2011 - Diarylpyrimidine-Dihydrobenzyloxopyrimidine Hybrids: New, Wide-Spectrum Anti-HIV-1 Agents Active at (Sub)-Nanomolar Level.
Rotili, Dante; Tarantino, D; Artico, M; Nawrozkij, Mb; Gonzalez Ortega, E; Clotet, B; Samuele, A; Este, Ja; Maga, G; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3091-3096 - issn: 0022-2623 - wos: WOS:000289697800043 (48) - scopus: 2-s2.0-79955455754 (53)

11573/442679 - 2011 - Simplification of the tetracyclic SIRT1-selective inhibitor MC2141: Coumarin- and pyrimidine-based SIRT1/2 inhibitors with different selectivity profile
Rotili, Dante; Vincenzo, Carafa; Domenico, Tarantino; Giorgia, Botta; Angela, Nebbioso; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 3659-3668 - issn: 0968-0896 - wos: WOS:000291477600007 (28) - scopus: 2-s2.0-79958261783 (31)

11573/379790 - 2011 - PHARMACOLOGICAL INHIBITION OF HDAC6 ATTENUATES ENDOTHELIAL BARRIER DYSFUNCTION INDUCED BY THROMBIN
Saito, S; Lasky, Ja; Guo, W; Nguyen, H; Mai, Antonello; Danchuk, S; Sullivan, De; Shan, B. - 01a Articolo in rivista
paper: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 630-634 - issn: 0006-291X - wos: WOS:000291293200022 (24) - scopus: 2-s2.0-79956216267 (25)

11573/884288 - 2011 - HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer
Stronach, Euan A; Alfraidi, Albandri; Rama, Nona; Datler, Christoph; Studd, James B.; Agarwal, Roshan; Guney, Tankut G.; Gourley, Charlie; Hennessy, Bryan T.; Mills, Gordon B.; Mai, Antonello; Brown, Robert; Dina, Roberto; Gabra, Hani - 01a Articolo in rivista
paper: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 4412-4422 - issn: 0008-5472 - wos: WOS:000292287300012 (147) - scopus: 2-s2.0-79959895071 (149)

11573/525044 - 2011 - Histone deacetylase inhibitors (epigenetic alterations)Targeted Therapies for Hepatocellular Carcinoma
Valente, Sergio; Mai, Antonello - 02a Capitolo o Articolo
book: Targeted Therapies for Hepatocellular Carcinoma - (9781780840628)

11573/436635 - 2011 - Novel Reversible Monoamine Oxidase A Inhibitors: Highly Potent and Selective 3-(1H-Pyrrol-3-yl)-2-oxazolidinones
Valente, Sergio; S., Tomassi; Tempera, Giampiero; Saccoccio, Stefania; Agostinelli, Enzo; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8228-8232 - issn: 0022-2623 - wos: WOS:000297445400024 (37) - scopus: 2-s2.0-82555187393 (37)

11573/356064 - 2011 - Novel Cinnamyl Hydroxyamides and 2-Aminoanilides as Histone Deacetylase Inhibitors: Apoptotic Induction and Cytodifferentiation Activity
Valente, Sergio; Tardugno, Maria; Mariarosaria, Conte; Roberto, Cirilli; Andrea, Perrone; Ragno, Rino; Simeoni, Silvia; Tramontano, Anna; Massa, Silvio; Angela, Nebbioso; Marco, Miceli; Gianluigi, Franci; Gerald, Brosch; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 698-712 - issn: 1860-7179 - wos: WOS:000288814900016 (17) - scopus: 2-s2.0-79953046146 (18)

11573/379616 - 2011 - Discovery, Synthesis, and Pharmacological Evaluation of Spiropiperidine Hydroxamic Acid Based Derivatives as Structurally Novel Histone Deacetylase (HDAC) Inhibitors.
Varasi, M; Thaler, F; Abate, A; Bigogno, C; Boggio, R; Carenzi, G; Cataudella, T; Dal Zuffo, R; Fulco, Mc; Rozio, Mg; Mai, Antonello; Dondio, G; Minucci, S; Mercurio, C. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3051-3064 - issn: 0022-2623 - wos: WOS:000289697800038 (48) - scopus: 2-s2.0-79955451248 (54)

11573/434969 - 2010 - HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation
A., Nebbioso; C., Dell'aversana; A., Bugge; R., Sarno; Valente, Sergio; Rotili, Dante; F., Manzo; D., Teti; S., Mandrup; P., Ciana; A., Maggi; Mai, Antonello; H., Gronemeyer; L., Altucci - 01a Articolo in rivista
paper: JOURNAL OF MOLECULAR ENDOCRINOLOGY (Pubblicata da: SOC ENDOCRINOLOGY, 22 APEX COURT, WOODLANDS, BRADLEY STOKE, BRISTOL, ENGLAND, BS32 4JT primo editore: Journal of Endocrinology Limited:17 18 Courtyard Woodlands, Bristol BS12 4NQ United Kingdom:011 44 117 9616046, EMAIL: sxa15@psu.edu, INTERNET: http://www.psu.edu, Fax: 011 44 117 9616071) pp. 219-228 - issn: 0952-5041 - wos: WOS:000282528800005 (52) - scopus: 2-s2.0-77957824326 (56)

11573/365281 - 2010 - Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases LSD1 and LSD2
Claudia, Binda; Valente, Sergio; Mauro, Romanenghi; Simona, Pilotto; Roberto, Cirilli; Aristotele, Karytinos; Giuseppe, Ciossani; Oronza A., Botrugno; Federico, Forneris; Maria, Tardugno; Dale E., Edmondson; Saverio, Minucci; Andrea, Mattevi; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ([Washington, USA: American Chemical Society] 1879-) pp. 6827-6833 - issn: 0002-7863 - wos: WOS:000277721500044 (236) - scopus: 2-s2.0-77952355653 (256)

11573/13665 - 2010 - Histone deacetylase inhibitors: Keeping momentum for neuromuscular and cardiovascular diseases treatment
Claudia, Colussi; Barbara, Illi; Jessica, Rosati; Spallotta, Francesco; Antonella, Farsetti; Annalisa, Grasselli; Mai, Antonello; Capogrossi Mc, Gaetano C. - 01g Articolo di rassegna (Review)
paper: PHARMACOLOGICAL RESEARCH (Attuale:ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 24-28 OVAL RD, LONDON, ENGLAND, NW1 7DX Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 3-10 - issn: 1043-6618 - wos: WOS:000278613800002 (39) - scopus: 2-s2.0-77952880971 (41)

11573/13728 - 2010 - Proteomic profile of differentially expressed plasma proteins from dystrophic mice and following suberoylanilide hydroxamic acid treatment
Colussi, C.; Banfi, C.; Brioschi, M.; Tremoli, E.; Straino, S.; Spallotta, F.; Mai, Antonello; Rotili, Dante; Capogrossi Mc, Gaetano C. - 01a Articolo in rivista
paper: PROTEOMICS. CLINICAL APPLICATIONS (Weinheim : Wiley-VCH-Verl.) pp. 71-83 - issn: 1862-8346 - wos: WOS:000274264900007 (30) - scopus: 2-s2.0-77951727320 (31)

11573/13666 - 2010 - The histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces cardiac arrhythmias in dystrophic mice
Colussi, C.; Berni, R.; Rosati, J.; Straino, S.; Vitale, S.; Spallotta, F.; Baruffi, S.; Bocchi, L.; Delucchi, F.; Rossi, S.; Savi, M.; Rotili, Dante; Quaini, F.; Macchi, E.; Stilli, D.; Musso, E.; Mai, Antonello; Capogrossi Mc, Gaetano C. - 01a Articolo in rivista
paper: CARDIOVASCULAR RESEARCH (editore attuale: ELSEVIER SCIENCE BV, PO BOX 211, AMSTERDAM, NETHERLANDS, 1000 AE primo editore: BMJ / British Medical Journal Publishing Group:PO Box 299, London WC1H 9TD United Kingdom:011 44 20 73836270, EMAIL: subscriptions@bmjgroup.com, INTERNET: http://www.bmjpg.com/bmj, Fax: 011 44 20 73836402) pp. 73-82 - issn: 0008-6363 - wos: WOS:000278690000012 (40) - scopus: 2-s2.0-77955165005 (42)

11573/434968 - 2010 - TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration
Daniela, Palacios; Mozzetta, Chiara; Silvia, Consalvi; Giuseppina, Caretti; Valentina, Saccone; Valentina, Proserpio; Victor E., Marquez; Valente, Sergio; Mai, Antonello; Sonia V., Forcales; Vittorio, Sartorelli; Pier Lorenzo, Puri - 01a Articolo in rivista
paper: CELL STEM CELL (Cambridge: Cell Press (an imprint of Elsevier)) pp. 455-469 - issn: 1934-5909 - wos: WOS:000283270600008 (318) - scopus: 2-s2.0-77957357566 (341)

11573/12800 - 2010 - Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation
E., Borbone; M. T., Berlingieri; F., De Bellis; A., Nebbioso; G., Chiappetta; Mai, Antonello; L., Altucci; A., Fusco - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 105-116 - issn: 0950-9232 - wos: WOS:000273373500010 (66) - scopus: 2-s2.0-73849114072 (69)

11573/13428 - 2010 - Synthesis and Biological Evaluation of N-Hydroxyphenylacrylamides and N-Hydroxypyridin-2-ylacrylamides as Novel Histone Deacetylase Inhibitors
Florian, Thaler; Andrea, Colombo; Mai, Antonello; Raffaella, Amici; Chiara, Bigogno; Roberto, Boggio; Anna, Cappa; Simone, Carrara; Tiziana, Cataudella; Fulvia, Fusar; Eleonora, Gianti; Samuele Joppolo Di, Ventimiglia; Maurizio, Moroni; Davide, Munari; Gilles, Pain; Nickolas, Regalia; Luca, Sartori; Stefania, Vultaggio; Giulio, Dondio; Stefania, Gagliardi; Saverio, Minucci; Ciro, Mercurio; Mario, Varasi - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 822-839 - issn: 0022-2623 - wos: WOS:000273672100028 (29) - scopus: 2-s2.0-77249133651 (30)

11573/13724 - 2010 - Synthesis and Biological Characterization of Amidopropenyl Hydroxamates as HDAC Inhibitors
Florian, Thaler; Mario, Varasi; Andrea, Colombo; Roberto, Boggio; Davide, Munari; Nickolas, Regalia; Marco G, Rozio; Veronica, Reali; Anna E, Resconi; Mai, Antonello; Stefania, Gagliardi; Giulio, Dondio; Saverio, Minucci; Ciro, Mercurio - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1359-1372 - issn: 1860-7179 - wos: WOS:000281061300021 (13) - scopus: 2-s2.0-77955098441 (14)

11573/12804 - 2010 - Histone deacetylase-3 Activation Promotes TNF-α Expression in Cardiomyocytes During Lipopolysaccharide Stimulation
Huaqing, Zhu; Limei, Shan; Peter W., Schiller; Mai, Antonello; Tianqing, Peng - 01a Articolo in rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 9429-9436 - issn: 0021-9258 - wos: WOS:000276165900015 (82) - scopus: 2-s2.0-77951226550 (91)

11573/121815 - 2010 - Combining 3-D QSAR with Ligand Based and Structure Based Alignment Procedures for in Silico Screening of New Hepatitis C Virus NS5B Polymerase Inhibitors
I., Musmuca; A., Caroli; Mai, Antonello; N., Kaushik Basu; P., Arora; Ragno, Rino - 01a Articolo in rivista
paper: JOURNAL OF CHEMICAL INFORMATION AND MODELING (AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036) pp. 662-676 - issn: 1549-9596 - wos: WOS:000276915200020 (48) - scopus: 2-s2.0-77951993951 (58)

11573/12801 - 2010 - Lysine Acetylation Regulates Bruton’s Tyrosine Kinase in B Cell Activation
Liu, Z; Mai, Antonello; Sun, J. - 01a Articolo in rivista
paper: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 244-254 - issn: 0022-1767 - wos: WOS:000272985300029 (12) - scopus: 2-s2.0-73949137382 (12)

11573/884290 - 2010 - Small-molecule chromatin-modifying agents: Therapeutic applications
Mai, Antonello - 01a Articolo in rivista
paper: EPIGENOMICS (London: Future Medicine, 2009-) pp. 307-324 - issn: 1750-1911 - wos: WOS:000278299100014 (25) - scopus: 2-s2.0-77954139965 (30)

11573/442677 - 2010 - Characterization of Sirtuin Inhibitors in Nematodes Expressing a Muscular Dystrophy Protein Reveals Muscle Cell and Behavioral Protection by Specific Sirtinol Analogues
Matthieu Y., Pasco; Rotili, Dante; Lucia, Altucci; Francesca, Farina; Guy A., Rouleau; Mai, Antonello; Christian, Neri - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1407-1411 - issn: 0022-2623 - wos: WOS:000274270900047 (37) - scopus: 2-s2.0-77249153712 (40)

11573/456124 - 2010 - The specific character of the reaction of derivatives of 2-thioxo-2,3-dihydropyrimidin-4(1H)-one with iodomethane and alkyl chloromethyl sulfides.
Novakov, Ia; Orlinson, B; Nawrozkij, Mb; Mai, Antonello; Artico, Marino; Rotili, Dante; Eremiychuk, As; Gordeeva, Ea; Brunilina, Ll; Este, J. A. - 01a Articolo in rivista
paper: CHEMISTRY OF HETEROCYCLIC COMPOUNDS (Consultants Bureau:A Division of Plenum Publishing Corporation, 233 Spring Street, Sixth Floor:New York, NY 10013:(800)221-9369, (212)620-8082, Fax: (212)463-0742) pp. - - issn: 0009-3122 - wos: WOS:000279454900010 (1) - scopus: 2-s2.0-77954638922 (0)

11573/895420 - 2010 - Evaluation of histone deacetylases as drug targets in Huntington's disease models
Quinti, Luisa; Chopra, Vanita; Rotili, Dante; Valente, Sergio; Amore, Allison; Franci, Gianluigi; Meade, Sarah; Valenza, Marta; Altucci, Lucia; Maxwell, Michele M.; Cattaneo, Elena; Hersch, Steven; Mai, Antonello; Kazantsev, Aleksey - 02a Capitolo o Articolo
book: PLOS CURRENTS - ()

11573/229854 - 2010 - Chemogenomic profiling of the cellular effects associated with histone H3 acetylation impairment by a quinoline-derived compound
Roberta, Ruotolo; Federica, Tosi; Stefano, Vernarecci; Ballario, Paola; Mai, Antonello; Patrizia, Filetici; Simone, Ottonello - 01a Articolo in rivista
paper: GENOMICS (Amsterdam The Netherlands; Boston: Elsevier :Orlando, FL: Academic Press Incorporated) pp. 272-280 - issn: 0888-7543 - wos: WOS:000283894300003 (11) - scopus: 2-s2.0-78649448009 (10)

11573/456116 - 2010 - Identification of Tri- and Tetracyclic Pyrimidinediones as Sirtuin Inhibitors
Rotili, Dante; Tarantino, Domenico; Vincenzo, Carafa; Ester, Lara; Sarah, Meade; Giorgia, Botta; Angela, Nebbioso; Jorg, Schemies; Manfred, Jung; Aleksey G, Kazantsev; Manel, Esteller; Mario F, Fraga; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 674-677 - issn: 1860-7179 - wos: WOS:000277725100005 (47) - scopus: 2-s2.0-77951697156 (46)

11573/230646 - 2010 - Design, Synthesis and Biological Evaluation of Carboxy Analogues of Arginine Methyltransferase Inhibitor 1 (AMI-1)
Sabrina, Castellano; Ciro, Milite; Ragno, Rino; Silvia, Simeoni; Mai, Antonello; Vittorio, Limongelli; Ettore, Novellino; Ingo, Bauer; Gerald, Brosch; Astrid, Spannhoff; Donghang, Cheng; Mark T., Bedford; Gianluca, Sbardella - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 398-414 - issn: 1860-7179 - wos: WOS:000275521200009 (57) - scopus: 2-s2.0-77249086700 (62)

11573/193713 - 2010 - HDACi di classe II inibiscono la resistenza indotta in vitro al fluconazolo in Cryptococcus spp
Simonetti, Giovanna; D'auria, Felicia Diodata; Panella, Simona; S., Di Meo; Passariello, Claudio; Mai, Antonello; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
book: 8° Congresso della Società Italiana di Microbiologia Farmaceutica - ()

11573/229552 - 2010 - Nitric oxide determines mesodermic differentiation of mouse embryonic stem cells by activating class IIa histone deacetylases: potential therapeutic implications in a mouse model of hindlimb ischemia
Spallotta, F; Rosati, J; Straino, S; Nanni, S; Grasselli, A; Ambrosino, V; Rotili, Dante; Valente, Sergio; Farsetti, A; Mai, Antonello; Capogrossi, Mc; Gaetano, C; Illi, B. - 01a Articolo in rivista
paper: STEM CELLS (Alphamed Press Incorporated:1 Prestige Place, Suite 290:Miamisburg, OH 45342:(937)291-2355, EMAIL: alphamedpress@alphamedpress.com, INTERNET: http://www.alphamedpress.com, Fax: (937)291-4229) pp. 431-442 - issn: 1066-5099 - wos: WOS:000277093700006 (50) - scopus: 2-s2.0-77950581254 (50)

11573/229551 - 2009 - Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence
Andrea, Savarino; Mai, Antonello; Sandro, Norelli; Sary El, Daker; Valente, Sergio; Rotili, Dante; Lucia, Altucci; Palamara, Anna Teresa; Enrico, Garaci - 01a Articolo in rivista
paper: RETROVIROLOGY (London : BioMed Central) pp. 52-52 - issn: 1742-4690 - wos: WOS:000267430700001 (96) - scopus: 2-s2.0-67649259174 (97)

11573/13145 - 2009 - Chiral HPLC separation and absolute configuration of novel S-DABO derivatives.
Cirilli, R; Ferretti, R; La Torre, F; Borioni, A; Fares, V; Camalli, M; Faggi, C; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
paper: CHIRALITY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 604-612 - issn: 0899-0042 - wos: WOS:000267250300007 (10) - scopus: 2-s2.0-67649403720 (11)

11573/360441 - 2009 - Modulatori epigenetici: potenziali target per strategie terapeutiche innovative
Di Vincenzo, N; Simonetti, Giovanna; Passariello, Claudio; Nencioni, Lucia; Panella, Simona; Mai, Antonello; Garaci, E; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
book: Giornate del Dipartimento di Scienze di Sanità Pubblica "G. Sanarelli" - ()

11573/12747 - 2009 - Histone acetyltransferase inhibitors and preclinical studies
Fabio, Manzo; Francesco Paolo, Tambaro; Mai, Antonello; A., Altucci - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 761-774 - issn: 1354-3776 - wos: WOS:000267103900003 (89) - scopus: 2-s2.0-67649379393 (93)

11573/456128 - 2009 - Reactions of 6-benzyl-5-methyl-2-(methylsulfanyl)pyrimidin-4(3H)-one with aliphatic and aliphatic-aromatic amines
I. A., Novakov; B. S., Orlinson; Mai, Antonello; Artico, Marino; Rotili, Dante; M. B., Navrotskii; E. A., Gordeeva; E. N., Savel'ev - 01a Articolo in rivista
paper: RUSSIAN JOURNAL OF ORGANIC CHEMISTRY (pubblicata da: MAIK NAUKA/INTERPERIODICA, C/O KLUWER ACADEMIC-PLENUM PUBLISHERS, 233 SPRING ST, NEW YORK, USA, NY, 10013-1578) pp. 773-776 - issn: 1070-4280 - wos: WOS:000266829300021 (5) - scopus: 2-s2.0-67049164618 (3)

11573/360909 - 2009 - Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.
Lara, E; Mai, Antonello; Calvanese, V; Altucci, L; Lopez Nieva, P; Martinez Chantar, Ml; Varela Rey, M; Rotili, Dante; Nebbioso, A; Ropero, S; Montoya, G; Oyarzabal, J; Velasco, S; Serrano, M; Witt, M; Villar Garea, A; Inhof, A; Mato, Jm; Esteller, M; Fraga, Mf - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 781-791 - issn: 0950-9232 - wos: WOS:000263320000001 (219) - scopus: 2-s2.0-60149091562 (239)

11573/456126 - 2009 - Stereoselective synthesis of 2-substituted 6-[1-(2,6-difluorophenyl)ethyl]-5-methylpyrimidin-4(3H)-ones.
Mai, Antonello; Artico, Marino; Rotili, Dante; Novakov, Ia; Orlinson, Bs; Navrotskii, Mb; Eremiichuk, As; Gordeeva, E. A. - 01a Articolo in rivista
paper: RUSSIAN JOURNAL OF ORGANIC CHEMISTRY (pubblicata da: MAIK NAUKA/INTERPERIODICA, C/O KLUWER ACADEMIC-PLENUM PUBLISHERS, 233 SPRING ST, NEW YORK, USA, NY, 10013-1578) pp. 1531-1534 - issn: 1070-4280 - wos: WOS:000271810500019 (1) - scopus: 2-s2.0-70450201365 (0)

11573/13146 - 2009 - Epi-drugs to fight cancer: From chemistry to cancer treatment, the road ahead
Mai, Antonello; Lucia, Altucci - 01a Articolo in rivista
paper: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 199-213 - issn: 1357-2725 - wos: WOS:000262620400025 (165) - scopus: 2-s2.0-56149090684 (180)

11573/361722 - 2009 - Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases
Mai, Antonello; Rotili, Dante; Tarantino, Domenico; Angela, Nebbioso; Sabrina, Castellano; Gianluca, Sbardella; Marc, Tini; Lucia, Altucci - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 1132-1135 - issn: 0960-894X - wos: WOS:000263295200021 (67) - scopus: 2-s2.0-59749103028 (72)

11573/442678 - 2009 - Histone deacetylase inhibitors and neurodegenerative disorders: Holding the promise
Mai, Antonello; Rotili, Dante; Valente, Sergio; Aleksey, Kazantsev - 01a Articolo in rivista
paper: CURRENT PHARMACEUTICAL DESIGN (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 3940-3957 - issn: 1381-6128 - wos: WOS:000271385600003 (69) - scopus: 2-s2.0-70649108817 (70)

11573/229211 - 2009 - New pyrrole-based histone deacetylase inhibitors: Binding mode, enzyme- and cell-based investigations
Mai, Antonello; Valente, Sergio; Angela, Nebbioso; Simeoni, Silvia; Ragno, Rino; Silvio, Massa; Gerald, Brosch; Floriana De, Bellis; Fabio, Manzo; Lucia, Altucci - 01a Articolo in rivista
paper: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 235-247 - issn: 1357-2725 - wos: WOS:000262620400028 (25) - scopus: 2-s2.0-55949088703 (27)

11573/12799 - 2009 - Study of 1,4-Dihydropyridine Structural Scaffold: Discovery of Novel Sirtuin Activators and Inhibitors
Mai, Antonello; Valente, Sergio; Sarah, Meade; Vincenzo, Carafa; Maria, Tardugno; Angela, Nebbioso; Andrea, Galmozzi; Nico, Mitro; Emma De, Fabiani; Lucia, Altucci; Aleksey, Kazantsev - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5496-5504 - issn: 0022-2623 - wos: WOS:000269655500022 (151) - scopus: 2-s2.0-69949096844 (157)

11573/12746 - 2009 - Pyrrole-Based Hydroxamates and 2-Aminoanilides: Histone Deacetylase Inhibition and Cellular Activities
Mariarosaria, Conte; Maria, Tardugno; Silvio, Massa; Angela, Nebbioso; Lucia, Altucci; Mai, Antonello; Valente, Sergio - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1411-1415 - issn: 1860-7179 - wos: WOS:000270027800002 (10) - scopus: 2-s2.0-69749113873 (10)

11573/13427 - 2009 - Histone post-translational modifications by HPLC-ESI-MS after HT29 cell treatment with HDAC inhibitors
Marina, Naldi; Natalia, Calonghi; Lanfranco, Masotti; Carola, Parolin; Valente, Sergio; Mai, Antonello; Vincenza, Andrisano - 01a Articolo in rivista
paper: PROTEOMICS (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 5437-5445 - issn: 1615-9853 - wos: WOS:000273515000006 (23) - scopus: 2-s2.0-73149088831 (26)

11573/434973 - 2009 - Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes.
Nebbioso, A; Manzo, F; Miceli, M; Conte, M; Manente, L; Baldi, A; De Luca, A; Rotili, Dante; Valente, Sergio; Mai, Antonello; Usiello, A; Gronemeyer, H; Altucci, L. - 01a Articolo in rivista
paper: EMBO REPORTS (Oxford : Oxford University Press, 2000-) pp. 776-782 - issn: 1469-221X - wos: WOS:000267599700022 (119) - scopus: 2-s2.0-67650083046 (120)

11573/227010 - 2009 - Non-cancer uses of histone deacetylase inhibitors: effects on infectious diseases and β-hemoglobinopathies
Rotili, Dante; Simonetti, Giovanna; A., Savarino; Palamara, Anna Teresa; Migliaccio, A. R.; Mai, Antonello - 01a Articolo in rivista
paper: CURRENT TOPICS IN MEDICINAL CHEMISTRY (Hilversum : Bentham Science Publishers) pp. 272-291 - issn: 1568-0266 - wos: WOS:000265798300006 (39) - scopus: 2-s2.0-65449142086 (47)

11573/358514 - 2009 - Inibitori delle Istone Deacetilasi di Classe II riducono la replicazione del virus influenzale in vitro
Simonetti, Giovanna; Panella, Simona; Nencioni, Lucia; Mai, Antonello; Garaci, E; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
book: 37° CONGRESSO NAZIONALE DELLA SOCIETA' ITALIANA DI MICROBIOLOGIA - ()

11573/361898 - 2008 - Histone deacetylase inhibitors and hemoglobin F induction in beta-thalassemia
A. R., Migliaccio; Rotili, Dante; A., Nebbioso; G., Atweh; Mai, Antonello - 01a Articolo in rivista
paper: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 2341-2347 - issn: 1357-2725 - wos: WOS:000259134100002 (13) - scopus: 2-s2.0-48349094044 (17)

11573/13144 - 2008 - HDAC-class II specific inhibition involves HDAC proteasome-dependent degradation mediated by RANBP2
Annamaria, Scognamiglio; Angela, Nebbioso; Fabio, Manzo; Valente, Sergio; Mai, Antonello; Lucia, Altucci - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 2030-2038 - issn: 0167-4889 - wos: WOS:000259917200036 (47) - scopus: 2-s2.0-50849143144 (49)

11573/13367 - 2008 - HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment
C., Colussi; Mozzetta, Chiara; A., Gurtner; B., Illi; J., Rosati; S., Straino; G., Ragone; M., Pescatori; G., Zaccagnini; A., Antonini; G., Minetti; F., Martelli; G., Piaggio; P., Gallinari; C., Steinkulher; E., Clementi; C., Dell'aversana; L., Altucci; Mai, Antonello; M. C., Capogrossi; Gaetano C., Puri Pl - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 19183-19187 - issn: 0027-8424 - wos: WOS:000261706600031 (223) - scopus: 2-s2.0-58049221125 (233)

11573/359674 - 2008 - SIRTUINS, THE NAD-DEPENDENT HISTONE DEACETYLASES, AS NEW THERAPEUTIC TARGETS IN TUMOR ANGIOGENESIS
Chiani, Francesco; Orecchia, A; Cesarini, Elisa; Avitabile, S; Scarponi, C; Albanesi, C; Mai, Antonello; Zambruno, G; Camilloni, Giorgio; Failla, C. - 04a Atto di comunicazione a congresso
book: 50th Annual Meeting of Italian Cancer Society - ()

11573/363940 - 2008 - Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases
Gianluca, Sbardella; Sabrina, Castellano; Caterina, Vicidomini; Rotili, Dante; Angela, Nebbioso; Marco, Miceli; Lucia, Altucci; Mai, Antonello - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 2788-2792 - issn: 0960-894X - wos: WOS:000255444300005 (82) - scopus: 2-s2.0-42949089945 (88)

11573/358405 - 2008 - Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling
Illi, B.; Dello Russo, Claudio; Colussi, C.; Rosati, J.; Pallaoro, M.; Spallotta, F.; Rotili, Dante; Valente, Sergio; Ragone, G.; Martelli, F.; Biglioli, P.; Steinkuhler, C.; Gallinari, P.; Mai, Antonello; Capogrossi, M. C.; Gaetano, C. - 01a Articolo in rivista
paper: CIRCULATION RESEARCH (Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320 PRimo editore: Baltimore, Md. : Grune & Stratton, c1953-) pp. 51-58 - issn: 0009-7330 - wos: WOS:000252217400009 (97) - scopus: 2-s2.0-37849010584 (102)

11573/13425 - 2008 - Epigenetric Multiple Ligands: Mixed Histone/Protein Methyltransferase, Acetyltransferase, and Class III Deacetylase (Sirtuin) Inhibitors
Mai, A.; Cheng, D; Bedford, M. T.; Valente, S; Nebbioso, A; Perrone, A; Brosch, G; Sbardella, G; De Bellis, F; Miceli, M; Altucci, L - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2279-2290 - issn: 0022-2623 - wos: WOS:000254709100033 (122) - scopus: 2-s2.0-41849146748 (128)

11573/363936 - 2008 - Novel uracil-based 2-aminoanilide and 2-aminoanilide-like derivatives: Histone deacetylase inhibition and in-cell activities
Mai, Antonello; Andrea, Perrone; Angela, Nebbioso; Rotili, Dante; Valente, Sergio; Maria, Tardugno; Silvio, Massa; Floriana De, Bellis; Lucia, Altucci - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 2530-2535 - issn: 0960-894X - wos: WOS:000255246400002 (25) - scopus: 2-s2.0-41849089386 (28)

11573/363647 - 2008 - 5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile.
Nawrozkij, Mb; Rotili, Dante; Tarantino, Domenico; Botta, G; Eremiychuk, As; Musmuca, Ira; Ragno, Rino; Samuele, A; Zanoli, S; Armand Ugón, M; Clotet Codina, I; Novakov, Ia; Orlinson, Bs; Maga, G; Esté, Ja; Artico, Marino; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4641-4652 - issn: 0022-2623 - wos: WOS:000258289800033 (54) - scopus: 2-s2.0-49449113636 (57)

11573/365241 - 2008 - Class II-selective histone deacetylase inhibitors. Part 2: Alignment-independent GRIND 3-D QSAR, homology and docking studies
Ragno, Rino; Silvia, Simeoni; Rotili, Dante; Antonella, Caroli; Giorgia, Botta; Gerald, Brosch; Silvio, Massa; Mai, Antonello - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 621-632 - issn: 0223-5234 - wos: WOS:000254777400019 (38) - scopus: 2-s2.0-40049110686 (46)

11573/362098 - 2008 - Substrate-induced stable enzyme-inhibitor complex formation allows tight binding of novel 2-aminopyrimidin-4(3H)-ones to drug-resistant HIV-1 reverse transcriptase mutants.
Samuele, A; Facchini, M; Rotili, Dante; Mai, Antonello; Artico, Marino; Armand Ugón, M; Esté, Ja; Maga, G. - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1412-1418 - issn: 1860-7179 - wos: WOS:000259628300014 (9) - scopus: 2-s2.0-54849438319 (9)

11573/226594 - 2008 - Modulatori epigenetici: una via alternativa nella terapia delle infezioni fungine sistemiche
Simonetti, Giovanna; Palamara, Anna Teresa; Passariello, Claudio; Di Vincenzo, N; Mai, Antonello; Garaci, E. - 04a Atto di comunicazione a congresso
book: Bollettino della SIM - ()

11573/13369 - 2008 - Specific Activity of Class II Histone Deacetylases in Human Breast Cancer Cells
V., Duong; C., Bret; L., Altucci; Mai, Antonello; C., Duraffourd; J., Loubersac; P. O., Harmand; S., Bonnet; Valente, Sergio; T., Maudelonde; V., Cavailles; N., Boulle - 01a Articolo in rivista
paper: MOLECULAR CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 1908-1919 - issn: 1541-7786 - wos: WOS:000261824800011 (84) - scopus: 2-s2.0-57749101152 (92)

11573/519300 - 2007 - Sirtuins modulate the inflammation response in skin microvascular endothelial cells
C. M., Failla; Chiani, Francesco; A., Orecchia; C., Albanesi; Cesarini, Elisa; C., Scarponi; Mai, Antonello; G., Zambruno; Camilloni, Giorgio - 04b Atto di convegno in volume
paper: JOURNAL OF INVESTIGATIVE DERMATOLOGY (Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680) pp. S88-S88 - issn: 0022-202X - wos: WOS:000249933400527 (0) - scopus: (0)
conference: 37th Annual Meeting of the European-Society-for-Dermatological-Research (Zurich; Switzerland)
book: JOURNAL OF INVESTIGATIVE DERMATOLOGY - ()

11573/13081 - 2007 - The therapeutic uses of chromatin-modifying agents
Mai, Antonello - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC TARGETS (--London United Kingdom:Informa Healthcare -London : Ashley, 2002-.) pp. 835-851 - issn: 1472-8222 - wos: WOS:000247105600011 (50) - scopus: 2-s2.0-34250316675 (56)

11573/363321 - 2007 - Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains
Mai, Antonello; Artico, Marino; Rotili, Dante; Tarantino, Domenico; Clotet Codina, I; Armand Ugón, M; Ragno, Rino; Simeoni, S; Sbardella, G; Nawrozkij, M. B.; Samuele, A; Maga, G; Esté, J. A. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5412-5424 - issn: 0022-2623 - wos: WOS:000250557100019 (58) - scopus: 2-s2.0-35848949355 (62)

11573/362130 - 2007 - Identification of two new synthetic histone deacetylase inhibitors that modulate globin gene expression in erythroid cells from healthy donors and patients with thalassemia
Mai, Antonello; K., Jelicic; Rotili, Dante; A., Di Noia; E., Alfani; Valente, Sergio; L., Altucci; A., Nebbioso; S., Massa; R., Galanello; G., Brosch; A. R., Migliaccio; G., Migliaccio - 01a Articolo in rivista
paper: MOLECULAR PHARMACOLOGY (American Society for Pharmacology and Experimental Therapeutics:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7024, EMAIL: pstoute@aspet.org, INTERNET: http://www.aspet.org, Fax: (301)634-7099) pp. 1111-1123 - issn: 0026-895X - wos: WOS:000250385300004 (29) - scopus: 2-s2.0-35548933854 (30)

11573/365178 - 2007 - Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans
Mai, Antonello; Rotili, Dante; Massa, Silvio; Gerald, Brosch; Simonetti, Giovanna; Passariello, Claudio; Palamara, Anna Teresa - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 1221-1225 - issn: 0960-894X - wos: WOS:000244943300017 (80) - scopus: 2-s2.0-33846938126 (85)

11573/240206 - 2007 - Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors
Mai, Antonello; Valente, Sergio; Donghang, Cheng; Andrea, Perrone; Ragno, Rino; Simeoni, Silvia; Gianluca, Sbardella; Gerald, Brosch; Mark T, Bedford - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 987-991 - issn: 1860-7179 - wos: WOS:000248065600003 (53) - scopus: 2-s2.0-41849112166 (52)

11573/364545 - 2007 - Novel pyrrole-containing histone deacetylase inhibitors endowed with cytodifferentiation activity
Mai, Antonello; Valente, Sergio; Rotili, Dante; Silvio, Massa; Giorgia, Botta; Gerald, Brosch; Marco, Miceli; Angela, Nebbioso; Lucia, Altucci - 01a Articolo in rivista
paper: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 1510-1522 - issn: 1357-2725 - wos: WOS:000248566700025 (14) - scopus: 2-s2.0-34447268739 (14)

11573/51617 - 2007 - Docking and 3-D QSAR Studies on SIRT2 Inhibitors: A GRID/GOLPE Approach on Different Series of Compounds.
Ragno, Rino; Mai, Antonello; Simeoni, Silvia; Caroli, Antonia; Rotili, Dante; Botta, Giorgia - 04a Atto di comunicazione a congresso
conference: Frontiers in CNS and Oncology Medicinal Chemistry, ACS-EFMC (Siena, Italy)
book: Frontiers in CNS and Oncology Medicinal Chemistry, ACS-EFMC - ()

11573/51660 - 2007 - New Aroyl-Pyrrolyl-Hydroxy-Amides APHAs: Class I and II Histone Deacetylase Inhibiting Activity and Binding Mode Analysis through Molecular Docking Experiments
Ragno, Rino; Mai, Antonello; Simeoni, Silvia; Caroli, Antonia; Valente, Sergio; Perrone, Andrea - 04a Atto di comunicazione a congresso
conference: Frontiers in CNS and Oncology Medicinal Chemistry, ACS-EFMC (Siena, Italy)
book: Frontiers in CNS and Oncology Medicinal Chemistry, ACS-EFMC - ()

11573/239247 - 2007 - Small Molecole Inhibitors of Histone Arginine Methyltransferases: Homology Modeling, Molecular Docking, Binding Mode Analysis, and Biological Evaluation.
Ragno, Rino; Silvia, Simeoni; Sabrina, Castellano; Caterina, Vicidomini; Mai, Antonello; Tramontano, Anna; Claudia, Bonaccini; Patrick, Trojer; D., Ingo Bauer; Gerald, Brosch; Gianluca, Sbardella - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1241-1253 - issn: 0022-2623 - wos: WOS:000244895900016 (94) - scopus: 2-s2.0-33947685838 (102)

11573/361993 - 2007 - Slow-, tight-binding HIV-1 reverse transcriptase non-nucleoside inhibitors highly active against drug-resistant mutants
Reynel, Cancio; Mai, Antonello; Rotili, Dante; Marino, Artico; Gianluca, Sbardella; Imma Clotet, Codina; José A, Este; Emmanuele, Crespan; Samantha, Zanoli; Ulrich, Hubscher; Silvio, Spadari; Giovanni, Maga - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 445-448 - issn: 1860-7179 - wos: WOS:000246011500006 (20) - scopus: 2-s2.0-34547939030 (22)

11573/237899 - 2007 - Regolazione epigenetica in Candida albicans: potenziale target per strategie terapeutiche innovative
Simonetti, Giovanna; Passariello, Claudio; N., Di Vincenzo; Mai, Antonello; E., Garaci; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
book: 35° CONGRESSO NAZIONALE SOCIETA' ITALIANA DI MICROBIOLOGIA - ()

11573/362194 - 2007 - Histone deacetylase inhibitors may reduce pathogenicity and virulence in Candida albicans
Simonetti, Giovanna; Passariello, Claudio; Rotili, Dante; Mai, Antonello; Enrico, Garaci; Palamara, Anna Teresa - 01a Articolo in rivista
paper: FEMS YEAST RESEARCH (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1371-1380 - issn: 1567-1356 - wos: WOS:000250298000018 (42) - scopus: 2-s2.0-35448985401 (43)

11573/12852 - 2007 - Quinoline Derivative MC1626, a Putative GCN5 Histone Acetyltransferase (HAT) Inhibitor, Exhinits HAT-Independent Activity against Toxoplasma gondii
Smith, At; Livingston, Mr; Mai, Antonello; Filetici, P; Queener, Sf; Sullivan W. J., Jr - 01a Articolo in rivista
paper: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (American Society for Microbiology:PO Box 11127:Birmingham, AL 35201:(800)633-4931, (205)995-1567, EMAIL: asm.nonmembers.subs@ebsco.com, INTERNET: http://www.asm.org, Fax: (205)995-1588) pp. 1109-1111 - issn: 0066-4804 - wos: WOS:000244665500050 (29) - scopus: 2-s2.0-33847681408 (32)

11573/362375 - 2006 - Analytical and semipreparative high performance liquid chromatography separation of stereoisomers of novel 3,4-dihydropyrimidin-4(3H)-one derivatives on the immobilised amylose-based Chiralpack IA chiral stationary phase.
Cirilli, R; Ferretti, R; Gallinella, B; La Torre, F; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
paper: JOURNAL OF SEPARATION SCIENCE (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 1399-1406 - issn: 1615-9306 - wos: WOS:000239291200011 (27) - scopus: 2-s2.0-33746470231 (29)

11573/12796 - 2006 - Inhibition of Histone Deacetylase Class I but not Class II is Critical for the Sensitization of Leukemic Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis
Inoue, S; Mai, Antonello; Dyer, Js; Cohen, Gm - 01a Articolo in rivista
paper: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 6785-6792 - issn: 0008-5472 - wos: WOS:000238825800044 (121) - scopus: 2-s2.0-33746144518 (129)

11573/358996 - 2006 - Small-Molecule Inhibitors of Histone Acetyltransferase Activity: Identification and Biological Properties
Mai, A; Rotili, D.; Tarantino, D; Ornaghi, P; Tosi, F; Vicidomini, C; Sbardella, G; Nebbioso, A; Miceli, M; Altucci, L; Filetici, P - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6897-6907 - issn: 0022-2623 - wos: WOS:000241894000031 (123) - scopus: 2-s2.0-33750989910 (130)

11573/12854 - 2006 - Identification of small molecules inhibitors of GCN5 histone acetyltransferase activity
Mai, Antonello; Rotili, Dante; Ornaghi, P; Tosi, F; Vicidomini, C; Sbardella, G; Nebbioso, A; Altucci, L; Filetici, P. - 01a Articolo in rivista
paper: ARKIVOC (ARKAT USA INC, C/O ALAN R KATRITZKY, UNIV FLORIDA, DEPT CHEMISTRY, PO BOX 117200, GAINESVILLE, USA, FL, 32611) pp. 24-37 - issn: 1551-7004 - wos: WOS:000242574600004 (6) - scopus: 2-s2.0-33744470562 (7)

11573/363353 - 2006 - Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors
Mai, Antonello; Silvio, Massa; Rotili, Dante; Silvia, Simeoni; Ragno, Rino; Giorgia, Botta; Angela, Nebbioso; Marco, Miceli; Lucia, Altucci; Gerald, Brosch - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6046-6056 - issn: 0022-2623 - wos: WOS:000240826200019 (58) - scopus: 2-s2.0-33749258885 (57)

11573/234238 - 2006 - Aroyl-pyrrolyl hydroxyamides: Influence of pyrrole C4-phenylacetyl substitution on histone deacetylase inhibition
Mai, Antonello; Silvio, Massa; Valente, Sergio; Silvia, Simeoni; Ragno, Rino; Patrizia, Bottoni; Roberto, Scatena; Gerald, Brosch - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 225-237 - issn: 1860-7179 - wos: WOS:000202945600008 (22) - scopus: 2-s2.0-33646483786 (23)

11573/234818 - 2006 - 3-D QSAR Studies on Histone Deacetylase Inhibitors. A GOLPE/GRID Approach on Different Series of Compounds.
Ragno, Rino; Simeoni, S; Valente, Sergio; Massa, S; Mai, Antonello - 01a Articolo in rivista
paper: JOURNAL OF CHEMICAL INFORMATION AND MODELING (AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036) pp. 1420-1430 - issn: 1549-9596 - wos: WOS:000237658400053 (42) - scopus: 2-s2.0-33745356936 (46)

11573/366703 - 2006 - One-Pot, High Yielding Synthesis of Novel Dihydrothiazolo[3,2-a]pyrimidinones
Rotili, Dante; Mai, Antonello; Ambrogio, I; G., Fabrizi - 01a Articolo in rivista
paper: SYNTHETIC COMMUNICATIONS (New York, NY : Taylor & Francis New York, NY: Marcel Dekker Incorporated) pp. 495-500 - issn: 0039-7911 - wos: WOS:000234819600013 (0) - scopus: 2-s2.0-31744445689 (1)

11573/363623 - 2006 - 6-Alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): Novel Regulators of Cell Differentiation and Proliferation
Sbardella, G; Bartolini, S; Castellano, S; Artico, Marino; Paesano, N; Rotili, Dante; Spadafora, C; Mai, Antonello - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1073-1080 - issn: 1860-7179 - wos: WOS:000202946300006 (13) - scopus: 2-s2.0-33750284393 (14)

11573/197018 - 2006 - Nuove strategie per il superamento della farmaco-resistenza in Candida albicans
Simonetti, Giovanna; Passariello, Claudio; N., Di Vincenzo; V., Sgherri; Mai, Antonello; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
book: 3° Congresso Nazionale della Società Italiana di Microbiologia Farmaceutica - ()

11573/365771 - 2005 - 3-(1H-Pyrrol-2-yl)-2-oxazolidinones as novel monoamine oxidase type A inhibitors.
Mai, A; Artico, M.; Valente, S; Sbardella, G; Turini, P; Befani, O; Dalla Vedova, L; Agostinelli, E - 01a Articolo in rivista
paper: MEDICINAL CHEMISTRY (Bentham Science Publishers Ltd) pp. 117-124 - issn: 1573-4064 - wos: (0) - scopus: 2-s2.0-33846116762 (8)

11573/236120 - 2005 - 5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family
Mai, Antonello; Artico, Marino; Ragno, Rino; Gianluca, Sbardella; Silvio, Massa; Chiara, Musiu; Massimo, Mura; Flavia, Marturana; Alessandra, Cadeddu; Giovanni, Maga; Paolo La, Colla - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 2065-2077 - issn: 0968-0896 - wos: WOS:000227576700017 (51) - scopus: 2-s2.0-13844316071 (55)

11573/526020 - 2005 - Histone Deacetylation in Epigenetics: An Attractive Target for Anticancer Therapy
Mai, Antonello; Massa, S; Rotili, Dante; Cerbara, I; Valente, Sergio; Pezzi, R; Simeoni, S; Ragno, Rino - 01a Articolo in rivista
paper: MEDICINAL RESEARCH REVIEWS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 261-309 - issn: 0198-6325 - wos: WOS:000228224900001 (303) - scopus: 2-s2.0-16844362441 (321)

11573/13036 - 2005 - Synthesis and biological evaluation of 2-, 3-, and 4-acylaminocinnamyl-N-hydroxyamides as novel synthetic HDAC inhibitors.
Mai, Antonello; S., Massa; R., Pezzi; P., Loidl; G., Brosch; Valente, Sergio - 01a Articolo in rivista
paper: MEDICINAL CHEMISTRY (Bentham Science Publishers Ltd) pp. 245-254 - issn: 1573-4064 - wos: (0) - scopus: 2-s2.0-25144492801 (27)

11573/364675 - 2005 - Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides
Mai, Antonello; Silvio, Massa; Riccardo, Pezzi; Silvia, Simeoni; Rotili, Dante; Angela, Nebbioso; Annamaria, Scognamiglio; Lucia, Altucci; Peter, Loidl; Gerald, Brosch - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3344-3353 - issn: 0022-2623 - wos: WOS:000228871700031 (189) - scopus: 2-s2.0-20944435415 (195)

11573/364679 - 2005 - Exploring the connection unit in the HDAC inhibitor pharmacophore model: Novel uracil-based hydroxamates
Mai, Antonello; Silvio, Massa; Rotili, Dante; Riccardo, Pezzi; Patrizia, Bottoni; Roberto, Scatena; Joachim, Meraner; Gerald, Brosch - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 4656-4661 - issn: 0960-894X - wos: WOS:000232465900002 (45) - scopus: 2-s2.0-25144444434 (48)

11573/364994 - 2005 - Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (sirtuin) inhibitors
Mai, Antonello; Silvio, Massa; Siva, Lavu; Riccardo, Pezzi; Silvia, Simeoni; Ragno, Rino; Mariotti, Francesca Romana; Chiani, Francesco; Camilloni, Giorgio; David A., Sinclair - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 7789-7795 - issn: 0022-2623 - wos: WOS:000233654900028 (152) - scopus: 2-s2.0-28144438533 (162)

11573/363627 - 2005 - A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast
Prisca, Ornaghi; Rotili, Dante; Gianluca, Sbardella; Mai, Antonello; Patrizia, Filetici - 01a Articolo in rivista
paper: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited -London ; New York : Pergamon Press, 1958-) pp. 911-917 - issn: 0006-2952 - wos: WOS:000231663100011 (36) - scopus: 2-s2.0-23744453206 (38)

11573/364674 - 2005 - 6-[1-(2,6-difluorophenyl)ethyl]pyrimidinones antagonize cell proliferation and induce cell differentiation by inhibiting (a nontelomeric) endogenous reverse transcriptase
Sara, Bartolini; Mai, Antonello; Artico, Marino; Nicola, Paesano; Rotili, Dante; Corrado, Spadafora; Gianluca, Sbardella - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6776-6778 - issn: 0022-2623 - wos: WOS:000233017300003 (51) - scopus: 2-s2.0-27444434731 (51)

11573/197017 - 2005 - Attività di inibitori sintetici di istone deacetilasi sull'acquisizione di resistenza agli azolici in Candida albicans
Simonetti, Giovanna; Passariello, Claudio; Mai, Antonello; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
book: 33° Congresso Nazionale Società Italiana di Microbiologia - ()

11573/240328 - 2004 - Synthesis and biochemical evaluation of (R)-5-acyloxymethyl- and (S)-5-acylaminomethyl-3-(1H-pyrrol-1-yl)-2-oxazolidinones as new anti-monoamine oxidase (anti-MAO) agents.
Mai, Antonello; Artico, Marino; Valente, Sergio; I., Cerbara; Befani, Olivia; Turini, Paola; L., Dalla Vedova; Agostinelli, Enzo - 01a Articolo in rivista
paper: ARKIVOC (ARKAT USA INC, C/O ALAN R KATRITZKY, UNIV FLORIDA, DEPT CHEMISTRY, PO BOX 117200, GAINESVILLE, USA, FL, 32611) pp. 23-43 - issn: 1551-7004 - wos: WOS:000222493900004 (6) - scopus: (0)

11573/13659 - 2004 - Antimalarial and Antileishmanial Activities of Aroyl-pyrrolyl-hydroxy-amides, a New Class of Histone Deacetylase Inhibitors
Mai, Antonello; I., Cerbara; Valente, Sergio; S., Massa; L. A., Walker; B. L., Tekwani - 01a Articolo in rivista
paper: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (American Society for Microbiology:PO Box 11127:Birmingham, AL 35201:(800)633-4931, (205)995-1567, EMAIL: asm.nonmembers.subs@ebsco.com, INTERNET: http://www.asm.org, Fax: (205)995-1588) pp. 1435-1436 - issn: 0066-4804 - wos: WOS:000220658600060 (49) - scopus: 2-s2.0-1642460965 (50)

11573/234811 - 2004 - 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 2. Effect of Pyrrole-C2 and/or -C4 Substitutions on Biological Activity
Mai, Antonello; S., Massa; I., Cerbara; Valente, Sergio; Ragno, Rino; P., Bottoni; R., Scatena; P., Loidl; G., Brosch - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1098-1109 - issn: 0022-2623 - wos: WOS:000189151500005 (60) - scopus: 2-s2.0-1242273835 (67)

11573/189567 - 2004 - Synthesis and evaluation of sirtinol analogues as yeast Sir2 and human SIRT inhibitors
Pezzi, R.; Rotili, D.; Simeoni, S.; Ragno, Rino; Mariotti, Francesca Romana; Chiani, Francesco; Camilloni, Giorgio; Massa, S.; Mai, Antonello - 04a Atto di comunicazione a congresso
book: XVIII International Symposium on Medicinal Chemistry - ()

11573/237666 - 2004 - Computer-Aided Design, Synthesis, and Anti-HIV-1 Activity in Vitro of 2-Alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as Novel Potent Non-Nucleoside Reverse Transcriptase Inhibitors, Also Active Against the Y181C Variant
Ragno, Rino; Mai, Antonello; G., Sbardella; Artico, Marino; S., Massa; C., Musiu; M., Mura; F., Marturana; A., Cadeddu; P., La Colla - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 928-934 - issn: 0022-2623 - wos: WOS:000188831300015 (82) - scopus: 2-s2.0-10744230514 (91)

11573/434777 - 2004 - 3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 3. Discovery of novel lead compounds through structure-based drug design and docking studies.
Ragno, Rino; Mai, Antonello; Massa, S; Cerbara, I; Valente, Sergio; Bottoni, P; Scatena, R; Jesacher, F; Loidl, P; Brosch, G. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. - - issn: 0022-2623 - wos: WOS:000220038700008 (64) - scopus: 2-s2.0-12144291023 (69)

11573/884300 - 2004 - Synthesis and in vitro antimycobacterial activity of novel 3-(1H-pyrrol-1-yl)-2-oxazolidinone analogues of PNU-100480
Sbardella, Gianluca; Mai, Antonello; Artico, Marino; Loddo, Roberta; Setzu, Maria Grazia; La Colla, Paolo - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 1537-1541 - issn: 0960-894X - wos: WOS:000220334000035 (63) - scopus: 2-s2.0-1542284725 (66)

11573/1147217 - 2004 - New 6-nitroquinolones: synthesis and antimicrobial activities
Sbardella, Gianluca; Mai, Antonello; Artico, Marino; Setzu, Maria Giovanna; Poni, Graziella; La Colla, Paolo - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001 Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 463-471 - issn: 0014-827X - wos: (0) - scopus: 2-s2.0-2642513828 (19)

11573/120507 - 2003 - Synthesis and biological evaluation of enantiomerically pure pyrrolyl- oxazolidinones as a new class of potent and selective monoamine oxidase type A inhibitors.
Mai, Antonello; Artico, Marino; M., Esposito; Ragno, Rino; G., Sbardella; S., Massa - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001 Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 231-241 - issn: 0014-827X - wos: (0) - scopus: 2-s2.0-0037373722 (25)

11573/218667 - 2003 - 3-(1H-pyrrol-2- and –3-yl)-2-oxazolidinones as novel potent and selective monoamine oxidase type A inhibitors.
Mai, Antonello; Cervara, I.; Valente, Sergio; Artico, Marino; Sbardella, G.; Befani, Olivia; Turini, Paola; Agostinelli, Enzo - 13a Altro ministeriale

11573/204734 - 2003 - 3-(1H-pyrrol-2- and –3-yl)-2-oxazolidinones as novel potent and selective monoamine oxidase type A inhibitors.
Mai, Antonello; I., Cervara; Valente, Sergio; Artico, Marino; G., Sbardella; Befani, Olivia; Turini, Paola; Agostinelli, Enzo - 04a Atto di comunicazione a congresso
book: 8th International Congress on Amino Acids and Proteins - ()

11573/366839 - 2003 - Discovery of (Aryloxo propenyl)pyrrolyl Hydroxyamides as Selective Inhibitors of Class IIa Histone Deacetylase Homologue HD1-A
Mai, Antonello; Massa, S.; Pezzi, R.; Rotili, Dante; Loidl, P.; Brosch, G. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4826-4829 - issn: 0022-2623 - wos: WOS:000186347400004 (61) - scopus: 2-s2.0-0242362600 (66)

11573/254722 - 2003 - 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-alkylamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 1. Design, Synthesis, Biological Evaluation, and Binding Mode Studies Performed through Three Different Docking Procedures
Mai, Antonello; S., Massa; Ragno, Rino; I., Cerbara; F., Jesacher; P., Loidl; G., Brosch - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 512-524 - issn: 0022-2623 - wos: WOS:000180836600008 (107) - scopus: 2-s2.0-0037434511 (121)

11573/53426 - 2003 - Chemical Manipulations on 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-alkylamides, a New Class of Synthetic Histone Deacetylase Inhibitors: Towards an Histone Class Selectivity?
Mai, Antonello; Silvio, Massa; Ilaria, Cerbara; Ragno, Rino; Peter, Loidl; Gerald, Brosch - 04a Atto di comunicazione a congresso
book: APOPTOSIS 2003 - ()

11573/884301 - 2003 - Role of endogenous reverse transcriptase in murine early embryo development
Pittoggi, Carmine; Sciamanna, Ilaria; Mattei, Elisabetta; Beraldi, Rosanna; Lobascio, Anna Maria; Mai, Antonello; Quaglia, Maria Giovanna; Lorenzini, Rodolfo; Spadafora, Corrado - 01a Articolo in rivista
paper: MOLECULAR REPRODUCTION AND DEVELOPMENT (New York N.Y.: Wiley) pp. 225-236 - issn: 1040-452X - wos: WOS:000185632800003 (64) - scopus: 2-s2.0-0141571160 (61)

11573/53414 - 2002 - Synthesis and Biological Evaluation of Enantiomerically Pure 3-(1H-Pyrrol-1-yl)-2-oxazolidinones as a New Class of Potent and Selective Monoamine Oxidase Type A Inhibitors
G., Sbardella; Mai, Antonello; Artico, Marino; S., Massa; Ragno, Rino; M., Esposito; O., Befani; V., Giovannini; B., Mondov - 04a Atto di comunicazione a congresso
book: XVIIth International Symposium on Medical Chemistry - ()

11573/252009 - 2002 - 3-(1H-pyrrol-1-yl)-2-oxazolidinones as reversible, highly potent, and selective inhibitors of monoamine oxidase type A.
Mai, Antonello; Artico, M.; Esposito, M.; Sbardella, G.; Massa, S.; Befani, O.; Turini, Paola; Giovannini, V.; Mondovi', Bruno - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1180-1183 - issn: 0022-2623 - wos: WOS:000174506200003 (49) - scopus: 2-s2.0-0037075787 (49)

11573/53416 - 2002 - Computer-Aided Design of Novel Aroyl-pyrrolyl-hydroxy-alkylamide (APHA) Derivatives as New Synthetic Histone Deacetylase Inhibitors
Mai, Antonello; I., Cerbara; S., Massa; Ragno, Rino; G., Sbardella; F., Jesacher; P., Loidl; G., Brosch - 04a Atto di comunicazione a congresso
book: XVIIth International Symposium on Medical Chemistry - ()

11573/254380 - 2002 - Binding Mode Analysis of 3-(4-Benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: a New Synthetic Histone Deacetylase Inhibitor Inducing Histone Hyperacetylation, Growth Inhibition, and Terminal Cell Differentiation
Mai, Antonello; Massa, S.; Ragno, Rino; Esposito, M.; Sbardella, G.; Nocca, G.; Scatena, R.; Jesacher, F.; Loidl, P.; Brosch, G. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1778-1784 - issn: 0022-2623 - wos: WOS:000175168700006 (64) - scopus: 2-s2.0-0037171823 (70)

11573/12979 - 2001 - A new facile and expeditious synthesis of N-hydroxy-N\'-phenyloctanediamide, a potent inducer of terminal cytodifferentiation
Mai, Antonello; Esposito, M; Sbardella, G; Massa, S. - 01a Articolo in rivista
paper: ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL (Organic Preparations and Procedures Incorporated:PO Box 610009:Newton Highlands, MA 02161:(617)287-6130, EMAIL: jp.anselme@umb.edu, Fax: (617)287-6030) pp. 391-394 - issn: 0030-4948 - wos: WOS:000169959200013 (54) - scopus: 2-s2.0-0035536590 (57)

11573/248287 - 2001 - Structure-Based Design, Synthesis and Biological Evaluation of Conformationally Restricted Novel 2-Alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as Non-nucleoside Inhibitors of HIV-1 Reverse Transcriptase
Mai, Antonello; Sbardella, G; Artico, Marino; Ragno, Rino; Massa, S; Novellino, E; Greco, G; Lavecchia, A; Musiu, C; La Colla, M; Murgioni, C; La Colla, P. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2544-2554 - issn: 0022-2623 - wos: WOS:000170167700007 (85) - scopus: 2-s2.0-0035797356 (97)

11573/13654 - 2001 - 3,4-Dihydro-2-alkoxy-6-benzyl-oxopyrimidines (DABOs): Development of a Potent Class of Non-nucleoside Reverse Transcriptase Inhibitors
Marongiu, M. E.; Pani, A.; Musiu, C.; La Colla, P.; Mai, Antonello; Sbardella, G.; Massa, S.; Artico, M. - 02a Capitolo o Articolo
book: Recent developments in antiviral research - (817895012X)

11573/12978 - 2001 - 3-(4-aroyl-1h-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors
Massa, S; Mai, Antonello; Sbardella, G; Esposito, M; Ragno, Rino; Loidl, P; Brosch, G. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2069-2072 - issn: 0022-2623 - wos: WOS:000169367000004 (73) - scopus: 2-s2.0-0035927427 (82)

11573/13590 - 2001 - DABOs as candidates to prevent mucosal HIV transmission
Pani, A; Musiu, C; Loi A., G; Mai, Antonello; Loddo, R; La Colla, P; Marongiu, M. E. - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 51-59 - issn: 0956-3202 - wos: (0) - scopus: 2-s2.0-0034815526 (27)

11573/253561 - 2001 - Chiral resolution and molecular modeling investigation of rac-2-cyclopentylthio-6-[1-(2,6-difluorophenyl)ethyl]-3,4-dihydro-5- methylpyrimidin-4(3H)-one (MC-1047), a potent anti-HIV-1 reverse transcriptase agent of the DABO class.
Quaglia, M. G.; Mai, Antonello; Sbardella, G.; Artico, Marino; Ragno, Rino; Massa, S.; Del Piano, D.; Setzu, G.; Doratiotto, S.; Cotichini, V. - 01a Articolo in rivista
paper: CHIRALITY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 75-80 - issn: 0899-0042 - wos: WOS:000166596300002 (27) - scopus: 2-s2.0-0035146092 (31)

11573/255442 - 2001 - Structure-activity relationship studies on new DABOs: effect of substitutions at pyrimidine C-5 and C-6 positions on anti-HIV-1 activity
Sbardella, G.; Mai, Antonello; Artico, M.; Chimenti, Paola; Massa, S.; Loddo, R.; Marongiu, M. E.; La Colla, P.; Pani, A. - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 37-50 - issn: 0956-3202 - wos: WOS:000176040800002 (28) - scopus: 2-s2.0-0034975054 (29)

11573/254785 - 2000 - Does the 2-methylthiomethyl substituent really confer high anti-HIV-1 activity to S-DABOs ?
Sbardella, G; Mai, Antonello; Artico, Marino; Massa, S; Marceddu, T; Vargiu, L; Marongiu M., E; La Colla, P. - 01a Articolo in rivista
paper: MEDICINAL CHEMISTRY RESEARCH (Birkhauser Boston Incorporated:c/o Springer Verlag, PO Box 2485:Secaucus, NJ 07096:(800)777-4643, (973)348-4033, Fax: (973)348-4505) pp. 30-39 - issn: 1054-2523 - wos: (0) - scopus: 2-s2.0-0033943608 (28)

11573/247380 - 1999 - Nitroquinolones with Broad-Spectrum Antimycobacterial Activity in Vitro.
Artico, Marino; Mai, Antonello; Sbardella, G; Massa, S; Musiu, C; Lostia, S; Demontis, F; La Colla, P. - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 1651-1656 - issn: 0960-894X - wos: WOS:000080896500005 (24) - scopus: 2-s2.0-0033591758 (33)

11573/256812 - 1999 - 5-alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3,4-dihydropyrimidin-4(3h)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives
Mai, Antonello; Artico, Marino; Sbardella, G.; Massa, S.; Novellino, E.; Greco, G.; Loi, A. G.; Tramontano, E.; Marongiu, M. E.; La Colla, P. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 619-627 - issn: 0022-2623 - wos: WOS:000078826300011 (108) - scopus: 2-s2.0-0033602141 (123)

11573/256998 - 1999 - N-[4-(1,1'-Biphenylyl)methyl]-4-(4-thiomorpholinylmethyl)benzenamines, a New Class of Synthetic Antituberculosis Agents Active Against Mycobacterium Avium.
Mai, Antonello; Sbardella, G.; Artico, Marino; Massa, S.; Lampis, G.; Deidda, D.; Pompei, R. - 01a Articolo in rivista
paper: MEDICINAL CHEMISTRY RESEARCH (Birkhauser Boston Incorporated:c/o Springer Verlag, PO Box 2485:Secaucus, NJ 07096:(800)777-4643, (973)348-4033, Fax: (973)348-4505) pp. 149-161 - issn: 1054-2523 - wos: WOS:000080663900001 (1) - scopus: 2-s2.0-0032996022 (1)

11573/242616 - 1998 - CRYSTAL STRUCTURE OF 2-[5-(4-CARBETOXYPHENOXY)PENTANOYL]-5-CHLOROTHIOPHENE, C18H19O4ClS
A., Ettorre; Artico, Marino; Mai, Antonello; Ragno, Rino; Porretta, Giulio Cesare; S., Massa - 01a Articolo in rivista
paper: ZEITSCHRIFT FUR KRISTALLOGRAPHIE (R Oldenbourg Verlag:Rosenheimerstrasse 145, D 81671 Munich Germany:011 49 89 45051229, INTERNET: http://www.oldenbourg.de, Fax: 011 49 89 45051207) pp. 129-130 - issn: 0044-2968 - wos: (0) - scopus: (0)

11573/257184 - 1998 - N-[4-(1,1'-Biphenyl)methyl]-4-(4-thiomorpholinylmethyl)benzenamines as non-oxazolidinone analogues of antimycobacterial U-100480.
Artico, Marino; Mai, Antonello; Sbardella, G; Massa, S; Lampis, G; Deidda, D; Pompei, R. - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 1493-1498 - issn: 0960-894X - wos: WOS:000074291800010 (16) - scopus: 2-s2.0-0032537533 (20)

11573/12752 - 1998 - crystal structure of 3,4-dihydro-6-(3\'-methylbenzyl)-2-((1-methylpropyl)thio)-4-oxopyrimidine (S-dabo 618), C16H20N2OS and 3,4-dihydro-2-((1-methylpropyl)thio)-6-(2-naphthylmethyl)-4-oxopyrimidine (datno 774), C19H20N2OS, two HIV-1 reverse transcriptase inhibitors
Ettorre, A; Mai, Antonello; Sbardella, G; Artico, M; La Colla, P; Massa, S. - 01a Articolo in rivista
paper: ZEITSCHRIFT FUR KRISTALLOGRAPHIE (R Oldenbourg Verlag:Rosenheimerstrasse 145, D 81671 Munich Germany:011 49 89 45051229, INTERNET: http://www.oldenbourg.de, Fax: 011 49 89 45051207) pp. 593-595 - issn: 0044-2968 - wos: WOS:000074680700076 (4) - scopus: (0)

11573/1147212 - 1997 - Arylketotetramethylene analogues of disoxaril with anti-human rhinovirus 14 activity
Mai, A.; Artico, M.; Sbardella, G.; Massa, S.; De Montis, Andrea; Puddu, I.; Musiu, C.; La Colla, P. - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 235-242 - issn: 0956-3202 - wos: WOS:A1997WY39600007 (1) - scopus: 2-s2.0-0031009277 (2)

11573/12973 - 1997 - dihydro(alkylthio)(naphthylmethyl)oxopyrimidines: novel non-nucleoside reverse transcriptase inhibitors of the S-DABO series
Mai, Antonello; Artico, M; Sbardella, G; Quartarone, S; Massa, S; Loi A., G; De Montis, A; Scintu, F; Putzolu, M; La Colla, P. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1447-1454 - issn: 0022-2623 - wos: WOS:A1997WY39500005 (111) - scopus: 2-s2.0-15444340492 (125)

11573/244117 - 1996 - Investigation on QSAR and Binding Mode of a New Class of Human Rhinovirus-14 Inhibitors by CoMFA and Docking Experiments.
Artico, Marino; M., Botta; F., Corelli; Mai, Antonello; S., Massa; Ragno, Rino - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 1715-1724 - issn: 0968-0896 - wos: WOS:A1996VU12500017 (8) - scopus: 2-s2.0-0030272824 (10)

11573/247245 - 1996 - 6-(3-methylbenzyl)-2-(2-methylpropyl)thio-4(3h)-pyrimidinone (dabo 622)
Ettorre, A; Mai, Antonello; Artico, Marino; Massa, S; De Montis, A; La Colla, P. - 01a Articolo in rivista
paper: ACTA CRYSTALLOGRAPHICA. SECTION C, CRYSTAL STRUCTURE COMMUNICATIONS (Blackwell Munksgaard:PO Box 2148, Periodicals Department, DK-1016 Copenhagen K Denmark:011 45 33 755913, EMAIL: agentservices@oxon.blackwellpublishing.com, INTERNET: http://www.blackwellmunksgaard.com, Fax: 011 45 77 333377) pp. 2115-2117 - issn: 0108-2701 - wos: WOS:A1996VG08200099 (14) - scopus: 2-s2.0-0030213813 (16)

11573/247246 - 1996 - Methyl-2-thienylketopolymethyleneoxyphenyl derivatives of alkyl-substituted 4,5-dihydro-oxazoles with anti-human picornavirus activity.
Mai, Antonello; Artico, Marino; S., Massa; Ragno, Rino; A., De Montis; S., Corrias; M. G., Spiga; P., La Colla - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 213-220 - issn: 0956-3202 - wos: WOS:A1996UX10500007 (3) - scopus: 2-s2.0-0029901071 (3)

11573/246586 - 1995 - Synthesis and anti-HIV-1 Activity of Thio Analogues of Dihydro alkoxybenzyl oxopyrimidines
Mai, Antonello; Artico, Marino; Sbardella, G; Massa, S; Loi A., G; Tramontano, E; Scano, P; La Colla, P. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3258-3263 - issn: 0022-2623 - wos: (0) - scopus: 2-s2.0-0029095334 (113)

11573/246108 - 1995 - Pyrrolobenzodiazepines with antinociceptive activity: synthesis and pharmacological activities.
Mai, Antonello; Di Santo, Roberto; Massa, S.; Artico, Marino; Pantaleoni, G. C.; Giorgi, R.; Coppolino, M. F.; Barracchini, A. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 593-601 - issn: 0223-5234 - wos: WOS:A1995RK67200008 (15) - scopus: 2-s2.0-0029075894 (17)

11573/12749 - 1995 - (((thienylcarbonyl)alkyl)oxy)phenyl)- and (((pyrrylcarbonyl)alkyl)oxy)phenyl)oxazoline derivatives with potent and selective antihuman rhinovirus activity
Massa, S; Corelli, F; Mai, Antonello; Ragno, Rino; De Montis, A; Loi A., G; Corrias, S; Marongiu M., E; La Colla, P.; Artico, Marino - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 803-809 - issn: 0022-2623 - wos: WOS:A1995QL25400007 (6) - scopus: 2-s2.0-0028923893 (7)

11573/244102 - 1995 - synthesis and antiviral activity of new 3,4-dihydro-2-alkoxy-6-benzyl-4-oxopyrimidines (DABOs), specific inhibitors of human immunodeficiency virus type 1
Massa, S; Mai, Antonello; Artico, Marino; Sbardella, G; Tramontano, E. E.; Loi, A. G.; Scano, P; La Colla, P. - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 1-8 - issn: 0956-3202 - wos: WOS:A1995QA06000001 (62) - scopus: 2-s2.0-0028869436 (68)

11573/246474 - 1995 - Comparative Molecular Field Analysis of New Human Rhinovirus-14 Inhibitors
Ragno, Rino; M., Botta; F., Corelli; Mai, Antonello; S., Massa; G. C., Porretta; M., Artico - 02a Capitolo o Articolo
book: QSAR AND MOLECULAR MODELLING: CONCEPTS, COMPUTATIONAL TOOLS AND BIOLOGICAL APPLICATIONS - ()

11573/247326 - 1994 - ANTIFUNGAL AGENTS .7. DICHLOROPHENYLPYRRYLIMIDAZOLYLMETHANE DERIVATIVES - SYNTHESIS AND ANTIFUNGAL ACTIVITIES
Massa, S.; Mai, Antonello; Ragno, Rino; Porretta, G. C.; Retico, A.; Simonetti, Giovanna; Artico, M. - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001 Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 51-55 - issn: 0014-827X - wos: WOS:A1994NB74600007 (1) - scopus: 2-s2.0-0028302844 (1)

11573/12688 - 1994 - Characterization of the anti-HIV-1 activity of 3,4-dihydro-2-alkoxy-6-benzyl-4-oxopyrimidines (DABOs), new non-nucleoside reverse transcriptase inhibitors
Tramontano, E; Marongiu M., E; De Montis, A; Loi A., G; Artico, M; Massa, S; Mai, Antonello; La Colla, P. - 01a Articolo in rivista
paper: NEW MICROBIOLOGICA (-Pavia : Edizioni Internazionali, 2004 precedente: -Bologna: Luigi Ponzio e figlio) pp. 269-279 - issn: 1121-7138 - wos: (0) - scopus: 2-s2.0-0028522917 (35)

11573/14239 - 1993 - 3,4-dihydro-2-alkoxy-6-benzyl-4-oxopyrimidines (DABOs): a new class of specific inhibitors of human immunodeficiency virus type 1
Artico, M; Massa, S; Mai, Antonello; Marongiu M., E; Piras, G; Tramontano, E; La Colla, P. - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 361-368 - issn: 0956-3202 - wos: WOS:A1993ME94900008 (92) - scopus: 2-s2.0-0027521797 (97)

11573/247026 - 1993 - Antifungal Agents. 4. Synthesis of neo-Isopyrrolnitrin and other 3-Aryl-4-nitro-1H-pyrroles via TosMIC.
Massa, S; Di Santo, Roberto; Costi, Roberta; Mai, Antonello; Artico, M; Retico, A; Apuzzo, G; Artico, M; Simonetti, Giovanna - 01a Articolo in rivista
paper: MEDICINAL CHEMISTRY RESEARCH (Birkhauser Boston Incorporated:c/o Springer Verlag, PO Box 2485:Secaucus, NJ 07096:(800)777-4643, (973)348-4033, Fax: (973)348-4505) pp. 192-199 - issn: 1054-2523 - wos: (0) - scopus: (0)

11573/247239 - 1993 - 5,6-dihydro-4H-pyrrolo(1,2-a)(1,4)benzodiazepine-4,4-diacetic acid diethyl ester, an useful synthon for the synthesis of new polycyclic nitrogen systems of pharmacological interest
Massa, S; Mai, Antonello; Di Santo, Roberto; Artico, M. - 01a Articolo in rivista
paper: JOURNAL OF HETEROCYCLIC CHEMISTRY (Hetero Corporation:PO Box 170:Provo, UT 84603:(801)400-7373, EMAIL: jhetchem@yahoo.com, Fax: (801)356-7373) pp. 897-903 - issn: 0022-152X - wos: WOS:A1993MD59700009 (6) - scopus: 2-s2.0-0027453311 (8)

11573/14961 - 1993 - Synthesis and antifungal activities of aryl-1H-pyrrol-2-yl-1H-imidazol-1-yl-methane derivatives with unsaturated chains
Massa, S; Ragno, Rino; Porretta G., C; Mai, Antonello; Retico, A; Artico, M; Simonetti, N. - 01a Articolo in rivista
paper: ARCHIV DER PHARMAZIE (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 539-546 - issn: 0365-6233 - wos: WOS:A1993MB51500008 (12) - scopus: 2-s2.0-0027525303 (9)

11573/14962 - 1992 - one-pot synthesis of novel spiro-annelated pyrrole-containing heterocyclic system from suitable synthons
Artico, M; Massa, S; Mai, Antonello; Silvestri, R; Stefancich, G. - 01a Articolo in rivista
paper: JOURNAL OF HETEROCYCLIC CHEMISTRY (Hetero Corporation:PO Box 170:Provo, UT 84603:(801)400-7373, EMAIL: jhetchem@yahoo.com, Fax: (801)356-7373) pp. 241-245 - issn: 0022-152X - wos: (0) - scopus: (0)

11573/14963 - 1992 - pyrrolobenzodiazepines and related systems. 2. synthesis and biological properties of isonoraptazepine derivatives
Massa, S; Artico, M; Mai, Antonello; Corelli, F; Botta, M; Tafi, A; Pantaleoni, G. C.; Giorgi, R; Coppolino, M. F.; Cagnotto, A; Skorupska, M. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4533-4541 - issn: 0022-2623 - wos: WOS:A1992KA52000004 (21) - scopus: 2-s2.0-0027052394 (22)

11573/14543 - 1992 - synthesis of pyrazole analogues of isoaptazepine
Massa, S; Artico, M; Mai, Antonello; Mancuso, A; Corelli, F. - 01a Articolo in rivista
paper: JOURNAL OF HETEROCYCLIC CHEMISTRY (Hetero Corporation:PO Box 170:Provo, UT 84603:(801)400-7373, EMAIL: jhetchem@yahoo.com, Fax: (801)356-7373) pp. 1851-1854 - issn: 0022-152X - wos: (0) - scopus: (0)

11573/257032 - 1992 - Pyrrylphenylethanones Related to Cathinone and Lefetamine : Synthesis and Pharmacological Activities.
Massa, S; Di Santo, Roberto; Mai, Antonello; Artico, M; Pantaleoni G., C; Giorgi, R; Coppolino, M. F. - 01a Articolo in rivista
paper: ARCHIV DER PHARMAZIE (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 403-409 - issn: 0365-6233 - wos: WOS:A1992JF69600006 (2) - scopus: 2-s2.0-0026655175 (3)

11573/245036 - 1991 - Synthesis of New Disoxaril Analogues with Potent and Selective Anti-Human Rhinovirus 14 Activity
S., Massa; M., Artico; Mai, Antonello; Ragno, Rino; F., Corelli; A., Pani; M. E., Marongiu; E., Tramontano; P., La Colla - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 575-578 - issn: 0960-894X - wos: (0) - scopus: 2-s2.0-0026045626 (5)

11573/247522 - 1990 - Synthesis and Antimicrobial and Cytotoxic Activities of Pyrrole-containing Analogues of Trichostatin A.
Massa, S.; Artico, M.; Corelli, F.; Mai, Antonello; Di Santo, Roberto; Cortes, S.; Marongiu, M. E.; Pani, A.; La Colla, P. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2845-2849 - issn: 0022-2623 - wos: WOS:A1990EA37400026 (27) - scopus: 2-s2.0-0025102721 (29)

11573/14236 - 1990 - pyrrolobenzodiazepine and related systems. I. synthesis and pharmacological evaluation of new 5,6-dihydro-4H-pyrrolo(1,2-a)(1,4)benzodiazepine derivatives
Massa, S; Artico, M; Mai, Antonello; Corelli, F; Pantaleoni G., C; Giorgi, R; Ottaviani, D; Cagnotto, A. - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001 Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 1265-1281 - issn: 0014-827X - wos: WOS:A1990ET90100002 (11) - scopus: 2-s2.0-0025666693 (11)

11573/14309 - 1990 - spiro-(4H-pyrrolo(1,2-a)(1,4)benzodiazepine-4,4\'-piperidine)derivatives as potential nootropic agents: a simple one-pot synthesis
Massa, S; Mai, Antonello; Artico, M. - 01a Articolo in rivista
paper: SYNTHETIC COMMUNICATIONS (New York, NY : Taylor & Francis New York, NY: Marcel Dekker Incorporated) pp. 3537-3545 - issn: 0039-7911 - wos: WOS:A1990FD73600018 (10) - scopus: (0)

11573/13360 - 1990 - heterocyclic system. XI. synthesis of 1H,4H-pyrazolo(4,3-b)pyrrolizine and 2H,4H-pyrazolo(4,3-b)pyrrolizine derivatives
Massa, S; Mai, Antonello; Artico, M; Corelli, F. - 01a Articolo in rivista
paper: JOURNAL OF HETEROCYCLIC CHEMISTRY (Hetero Corporation:PO Box 170:Provo, UT 84603:(801)400-7373, EMAIL: jhetchem@yahoo.com, Fax: (801)356-7373) pp. 1805-1808 - issn: 0022-152X - wos: WOS:A1990EF97000053 (6) - scopus: 2-s2.0-0025081354 (7)

11573/470241 - 1990 - Research on antibacterial and antifungal agents. XIII. Synthesis and antimicrobial activity of 1-arylmethyl-4-aryl-1H-pyrrole-3-carboxylic acids
Silvio, Massa; Di Santo, Roberto; Mai, Antonello; M., Botta; Artico, Marco; S., Panico; Giovanna, Simonetti - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001 Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 833-846 - issn: 0014-827X - wos: WOS:A1990EA52000002 (20) - scopus: 2-s2.0-0025153041 (18)

11573/14308 - 1989 - acidi 5-aroil-5,6-diidro-4H-pirrolo(1,2-a)(1,4)benzodiazepin-4-carbossilici: sintesi ed attività analgesica e neurocomportamentale
Massa, S; Corelli, F; Artico, M; Mai, Antonello; Silvestri, R. - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001 Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 109-123 - issn: 0014-827X - wos: WOS:A1989U409700002 (12) - scopus: 2-s2.0-0024473787 (10)

11573/14235 - 1989 - research on antibacterial and antifungal agents. XI. new antibacterial quinolones related to pirfloxacin
Massa, S; Corelli, F; Mai, Antonello; Artico, M; Panico, S; Simonetti, N. - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001 Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 779-793 - issn: 0014-827X - wos: WOS:A1989AV95900002 (4) - scopus: 2-s2.0-0024424105 (4)

11573/14234 - 1989 - syntheses of 3b,4,6,7-tetrahydro-5H,9H-pyrazino(2,1-c)pyrrolo(1,2-a)(1,4)benzodiazepine, a valuable precursor of potential central nervous system agents
Massa, S; Mai, Antonello; Artico, M; Corelli, F; Botta, M. - 01a Articolo in rivista
paper: TETRAHEDRON (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 2763-2772 - issn: 0040-4020 - wos: WOS:A1989U501500024 (22) - scopus: (0)

11573/14241 - 1989 - synthesis and antifungal activities of 1-(p-methyl-a-(4-(1H-pyrrol-1-yl)phenyl)benzyl)azoles and some related products
Massa, S; Stefancich, G; Corelli, F; Silvestri, R; Mai, Antonello; Artico, M; Panico, S; Simonetti, N. - 01a Articolo in rivista
paper: ARCHIV DER PHARMAZIE (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 369-373 - issn: 0365-6233 - wos: (0) - scopus: 2-s2.0-0024678155 (14)

11573/14240 - 1988 - synthesis of a new tetracyclic system related to aptazapine (CGS 7525A) by one-pot double annelation
Massa, S; Mai, Antonello; Corelli, F. - 01a Articolo in rivista
paper: TETRAHEDRON LETTERS (Oxford; New York; Paris; Frankfurt: Pergamon Press, 1959-) pp. 6471-6474 - issn: 0040-4039 - wos: WOS:A1988R414700025 (14) - scopus: 2-s2.0-0024239164 (14)

11573/14960 - 1987 - vitamina C: attività a livello del sistema nervoso centrale
Barretta, V.; Mai, Antonello - 01a Articolo in rivista
paper: GIORNALE DI MEDICINA MILITARE (M D Uff AMM Spec G Medicina MI:via Marsala 104, 00185 Rome Italy:011 39 6 47357939) pp. 223-227 - issn: 0017-0364 - wos: (0) - scopus: (0)

11573/14233 - 1987 - ricerche su composti antibatterici ed antifungini. Nota VIII - sintesi ed attività antifungina di derivati pirrolici correlati con la tricostatina A
Corelli, F; Massa, S; Stefancich, G; Mai, Antonello; Artico, M; Panico, S; Simonetti, N. - 01a Articolo in rivista
paper: IL FARMACO. EDIZIONE SCIENTIFICA (Editoriale II Farmaco:PO Box 227, 27100 Pavia Italy:(0382)23.061) pp. 893-903 - issn: 0430-0920 - wos: WOS:A1987M184000003 (9) - scopus: 2-s2.0-0023554206 (9)

11573/14232 - 1986 - cromatografia: aspetti termodinamici
Barretta, V.; Mai, Antonello - 01a Articolo in rivista
paper: GIORNALE DI MEDICINA MILITARE (M D Uff AMM Spec G Medicina MI:via Marsala 104, 00185 Rome Italy:011 39 6 47357939) pp. 448-451 - issn: 0017-0364 - wos: (0) - scopus: (0)

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