11573/1719671 - 2024 -
Aging exacerbates oxidative stress and liver fibrosis in an animal model of Down Syndrome Giallongo, S.; Ferrigno, J.; Caltabiano, R.; Broggi, G.; Alanazi, A. M.; Distefano, A.; Tropea, E.; Tramutola, A.; Perluigi, M.; Volti, G. L.; Barone, E.; Barbagallo, I. A. - 01a Articolo in rivista
rivista: AGING (Impact Journals LLC) pp. 10203-10215 - issn: 1945-4589 - wos: (0) - scopus: 2-s2.0-85197526238 (1)
11573/1709575 - 2024 -
Shaping down syndrome brain cognitive and molecular changes due to aging using adult animals from the Ts66Yah murine model Lanzillotta, Chiara; Baniowska, Monika Rataj; Prestia, Francesca; Sette, Chiara; Nalesso, Valérie; Perluigi, Marzia; Barone, Eugenio; Duchon, Arnaud; Tramutola, Antonella; Herault, Yann; Di Domenico, Fabio - 01a Articolo in rivista
rivista: NEUROBIOLOGY OF DISEASE (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 1-22 - issn: 0969-9961 - wos: WOS:001239384700001 (1) - scopus: 2-s2.0-85192167129 (2)
11573/1711799 - 2024 -
Biliverdin reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β Lanzillotta, Chiara; Tramutola, Antonella; Lanzillotta, Simona; Greco, Viviana; Pagnotta, Sara; Sanchini, Caterina; Di Angelantonio, Silvia; Forte, Elena; Rinaldo, Serena; Paone, Alessio; Cutruzzolà, Francesca; Cimini, Flavia Agata; Barchetta, Ilaria; Cavallo, Maria Gisella; Urbani, Andrea; Butterfield, D Allan; Di Domenico, Fabio; Paul, Bindu D; Perluigi, Marzia; Duarte, Joao M N; Barone, Eugenio - 01a Articolo in rivista
rivista: REDOX BIOLOGY (Amsterdam : Elsevier) pp. - - issn: 2213-2317 - wos: WOS:001251154800001 (0) - scopus: 2-s2.0-85195097821 (3)
11573/1678614 - 2023 -
Dynamic changes of BVRA protein levels occur in response to insulin: a pilot study in humans Cimini, Flavia Agata; Tramutola, Antonella; Barchetta, Ilaria; Ceccarelli, Valentina; Gangitano, Elena; Lanzillotta, Simona; Lanzillotta, Chiara; Cavallo, Maria Gisella; Barone, Eugenio - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 7282- - issn: 1422-0067 - wos: WOS:000979287800001 (2) - scopus: 2-s2.0-85158058924 (2)
11573/1700398 - 2023 -
Engineering memory with an extrinsically disordered kinase Ripoli, Cristian; Dagliyan, Onur; Renna, Pietro; Pastore, Francesco; Paciello, Fabiola; Sollazzo, Raimondo; Rinaudo, Marco; Battistoni, Martina; Martini, Sara; Tramutola, Antonella; Sattin, Andrea; Barone, Eugenio; Saneyoshi, Takeo; Fellin, Tommaso; Hayashi, Yasunori; Grassi, Claudio - 01a Articolo in rivista
rivista: SCIENCE ADVANCES (Washington, DC : American Association for the Advancement of Science, 2015-) pp. - - issn: 2375-2548 - wos: WOS:001125318400007 (5) - scopus: 2-s2.0-85178498372 (6)
11573/1666748 - 2023 -
Intranasal administration of KYCCSRK peptide rescues brain insulin signaling activation and reduces Alzheimer’s disease-like neuropathology in a mouse model for Down syndrome Tramutola, Antonella; Lanzillotta, Simona; Aceto, Giuseppe; Pagnotta, Sara; Ruffolo, Gabriele; Cifelli, Pierangelo; Marini, Federico; Ripoli, Cristian; Palma, Eleonora; Grassi, Claudio; Di Domenico, Fabio; Perluigi, Marzia; Barone, Eugenio - 01a Articolo in rivista
rivista: ANTIOXIDANTS (Basel: MDPI) pp. 111- - issn: 2076-3921 - wos: WOS:000916695100001 (14) - scopus: 2-s2.0-85146816588 (15)
11573/1700414 - 2023 -
GLUT-1 changes in paediatric Huntington disease brain cortex and fibroblasts: an observational case-control study Tramutola, Antonella; S Bakels, Hannah; Perrone, Federica; Di Nottia, Michela; Mazza, Tommaso; Abruzzese, Maria Pia; Zoccola, Martina; Pagnotta, Sara; Carrozzo, Rosalba; T De Bot, Susanne; Perluigi, Marzia; C Van Roon-Mom, Willeke M; Squitieri, Ferdinando - 01a Articolo in rivista
rivista: EBIOMEDICINE (Amsterdam : Elsevier) pp. - - issn: 2352-3964 - wos: WOS:001105268300001 (6) - scopus: 2-s2.0-85174839868 (7)
11573/1634188 - 2022 -
CAPE and its synthetic derivative VP961 restore BACH1/NRF2 axis in Down syndrome Pagnotta, S.; Tramutola, A.; Barone, E.; Di Domenico, F.; Pittala, V.; Salerno, L.; Folgiero, V.; Caforio, M.; Locatelli, F.; Petrini, S.; Butterfield, D. A.; Perluigi, M. - 01a Articolo in rivista
rivista: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 1-13 - issn: 0891-5849 - wos: WOS:000790734500001 (11) - scopus: 2-s2.0-85126271579 (15)
11573/1612865 - 2022 -
Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal-derived extracellular vesicles Perluigi, M.; Picca, A.; Montanari, E.; Calvani, R.; Marini, F.; Matassa, R.; Tramutola, A.; Villani, A.; Familiari, G.; Domenico, F. D.; Butterfield, D. A.; Oh, K. J.; Marzetti, E.; Valentini, D.; Barone, E. - 01a Articolo in rivista
rivista: ALZHEIMER'S & DEMENTIA (New York : Elsevier, c2005-) pp. 1498-1510 - issn: 1552-5260 - wos: WOS:000721478900001 (18) - scopus: 2-s2.0-85119666649 (18)
11573/1436701 - 2021 -
Circulating dipeptidyl peptidase-4 is independently associated with the presence and severity of NAFLD/NASH in individuals with and without obesity and metabolic disease Barchetta, I.; Ceccarelli, V.; Cimini, F. A.; Barone, E.; Sentinelli, F.; Coluzzi, M.; Chiappetta, C.; Bertoccini, L.; Tramutola, A.; Labbadia, G.; Di Cristofano, C.; Silecchia, G.; Leonetti, F.; Cavallo, M. G. - 01a Articolo in rivista
rivista: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (Springer
Milano: Editrice Kurtis Srl) pp. 979-988 - issn: 0391-4097 - wos: WOS:000564965600003 (27) - scopus: 2-s2.0-85089976237 (31)
11573/1456191 - 2021 -
Chronic perk induction promotes alzheimer-like neuropathology in down syndrome: Insights for therapeutic intervention Lanzillotta, C.; Zuliani, I.; Tramutola, A.; Barone, E.; Blarzino, C.; Folgiero, V.; Caforio, M.; Valentini, D.; Villani, A.; Locatelli, F.; Butterfield, D. A.; Head, E.; Perluigi, M.; Abisambra, J. F.; Di Domenico, F. - 01a Articolo in rivista
rivista: PROGRESS IN NEUROBIOLOGY (-Oxford:PERGAMON-ELSEVIER SCIENCE LTD,
-Oxford; New York; Toronto; Rushcutters Bay; Braunschweig: Pergamon Press Vieweg & Sohn.) pp. 1-17 - issn: 0301-0082 - wos: WOS:000604785900004 (19) - scopus: 2-s2.0-85089501564 (25)
11573/1487153 - 2021 -
Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: a harmful synergistic path in down syndrome Lanzillotta, Chiara; Tramutola, Antonella; Di Giacomo, Graziella; Marini, Federico; Butterfield, D Allan; Di Domenico, Fabio; Perluigi, Marzia; Barone, Eugenio - 01a Articolo in rivista
rivista: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 152-170 - issn: 0891-5849 - wos: WOS:000631946000004 (31) - scopus: 2-s2.0-85100251745 (31)
11573/1532739 - 2021 -
High-fat diet leads to reduced protein o-glcnacylation and mitochondrial defects promoting the development of Alzheimer’s disease signatures Zuliani, I.; Lanzillotta, C.; Tramutola, A.; Barone, E.; Perluigi, M.; Rinaldo, S.; Paone, A.; Cutruzzola', F.; Bellanti, F.; Spinelli, M.; Natale, F.; Fusco, S.; Grassi, C.; Di Domenico, F. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000638633700001 (19) - scopus: 2-s2.0-85103489586 (21)
11573/1474740 - 2021 -
The dysregulation of OGT/OGA cycle mediates Tau and APP neuropathology in down syndrome Zuliani, I.; Lanzillotta, C.; Tramutola, A.; Francioso, A.; Pagnotta, S.; Barone, E.; Perluigi, M.; Di Domenico, F. - 01a Articolo in rivista
rivista: NEUROTHERAPEUTICS (Orlando, FL: Elsevier, c2007-) pp. 340-363 - issn: 1933-7213 - wos: WOS:000594792400002 (14) - scopus: 2-s2.0-85096999977 (12)
11573/1463758 - 2020 -
Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity Bouzidi, Amani; Magnifico, Maria Chiara; Paiardini, Alessandro; Macone, Alberto; Boumis, Giovanna; Giardina, Giorgio; Rinaldo, Serena; Liberati, Francesca Romana; Lauro, Clotilde; Limatola, Cristina; Lanzillotta, Chiara; Tramutola, Antonella; Perluigi, Marzia; Sgarbi, Gianluca; Solaini, Giancarlo; Baracca, Alessandra; Paone, Alessio; Cutruzzolà, Francesca - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000595956300001 (11) - scopus: 2-s2.0-85096677891 (12)
11573/1456202 - 2020 -
Proteostasis failure in neurodegenerative diseases: focus on oxidative stress Hohn, A.; Tramutola, A.; Cascella, R. - 01a Articolo in rivista
rivista: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (London: Hindawi
AUSTIN, USA, TX: LANDES BIOSCIENCE) pp. - - issn: 1942-0900 - wos: WOS:000524595300001 (103) - scopus: 2-s2.0-85083306830 (109)
11573/1456172 - 2020 -
The BACH1/Nrf2 axis in brain in down syndrome and transition to alzheimer disease-like neuropathology and dementia Perluigi, Marzia; Tramutola, Antonella; Pagnotta, Sara; Barone, Eugenio; Allan Butterfield, D - 01a Articolo in rivista
rivista: ANTIOXIDANTS (Basel: MDPI) pp. - - issn: 2076-3921 - wos: WOS:000581301200001 (24) - scopus: 2-s2.0-85090534759 (27)
11573/1425664 - 2020 -
Multiple Herpes simplex virus-1 (HSV-1) reactivations induce protein oxidative damage in mouse brain. Novel mechanisms for Alzheimer’s disease progression Protto, Virginia; Tramutola, Antonella; Fabiani, Marco; Marcocci, Maria Elena; Napoletani, Giorgia; Iavarone, Federica; Vincenzoni, Federica; Castagnola, Massimo; Perluigi, Marzia; Di Domenico, Fabio; De Chiara, Giovanna; Palamara, Anna Teresa - 01a Articolo in rivista
rivista: MICROORGANISMS (Basel: MDPI) pp. 1-21 - issn: 2076-2607 - wos: WOS:000554284200001 (16) - scopus: 2-s2.0-85087114145 (19)
11573/1402452 - 2020 -
Oleoylethanolamide decreases frustration stress-induced binge-like eating in female rats: a novel potential treatment for binge eating disorder Romano, Adele; Micioni Di Bonaventura, Maria Vittoria; Gallelli, Cristina Anna; Koczwara, Justyna Barbara; Smeets, Dorien; Giusepponi, Maria Elena; De Ceglia, Marialuisa; Friuli, Marzia; Micioni Di Bonaventura, Emanuela; Scuderi, Caterina; Vitalone, Annabella; Tramutola, Antonella; Altieri, Fabio; Lutz, Thomas A; Giudetti, Anna Maria; Cassano, Tommaso; Cifani, Carlo; Gaetani, Silvana - 01a Articolo in rivista
rivista: NEUROPSYCHOPHARMACOLOGY (Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680) pp. 1931-1941 - issn: 0893-133X - wos: WOS:000530976300002 (37) - scopus: 2-s2.0-85085874970 (38)
11573/1381380 - 2020 -
Protein oxidative damage in UV-related skin cancer and dysplastic lesions contributes to neoplastic promotion and progression Tramutola, A.; Falcucci, S.; Brocco, U.; Triani, F.; Lanzillotta, C.; Donati, M.; Panetta, C.; Luzi, F.; Iavarone, F.; Vincenzoni, F.; Castagnola, M.; Perluigi, M.; Di Domenico, F.; De Marco, F. - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. 1-25 - issn: 2072-6694 - wos: WOS:000516826700110 (8) - scopus: 2-s2.0-85077526078 (9)
11573/1381801 - 2020 -
Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome Tramutola, A.; Lanzillotta, C.; Di Domenico, F.; Head, E.; Butterfield, D. A.; Perluigi, M.; Barone, E. - 01a Articolo in rivista
rivista: NEUROBIOLOGY OF DISEASE (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 104772- - issn: 0969-9961 - wos: WOS:000518709300017 (49) - scopus: 2-s2.0-85078670491 (55)
11573/1336175 - 2019 -
Greater circulating DPP4 activity is associated with impaired flow-mediated dilatation in adults with type 2 diabetes mellitus Barchetta, I.; Ciccarelli, G.; Barone, E.; Cimini, F. A.; Ceccarelli, V.; Bertoccini, L.; Sentinelli, F.; Tramutola, A.; Del Ben, M.; Angelico, F.; Baroni, M. G.; Lenzi, A.; Cavallo, M. G. - 01a Articolo in rivista
rivista: NMCD. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (-Amsterdam : Elsevier
-Berlin : Springer
-Milano: Medikal Press.) pp. 1087-1094 - issn: 0939-4753 - wos: WOS:000484832100012 (18) - scopus: 2-s2.0-85070712933 (17)
11573/1175653 - 2019 -
Biliverdin reductase-A mediates the beneficial effects of intranasal insulin in Alzheimer disease Barone, E; Tramutola, A; Triani, F; Calcagnini, S; Di Domenico, F; Ripoli, C; Gaetani, S; Grassi, C; Butterfield, Da; Cassano, T; Perluigi, M - 01a Articolo in rivista
rivista: MOLECULAR NEUROBIOLOGY (Humana Press Incorporated:999 Riverview Drive, Suite 208:Totowa, NJ 07512:(973)256-1699, EMAIL: lglasner@humanapr.com, INTERNET: http://www.humanapress.com, Fax: (973)256-8341) pp. 2922-2943 - issn: 0893-7648 - wos: WOS:000465498200050 (66) - scopus: 2-s2.0-85051645596 (73)
11573/1244127 - 2019 -
Reduced biliverdin reductase-a levels are associated with early alterations of insulin signaling in obesity Cimini, Flavia Agata; Arena, Andrea; Barchetta, Ilaria; Tramutola, Antonella; Ceccarelli, Valentina; Lanzillotta, Chiara; Fontana, Mario; Bertoccini, Laura; Leonetti, Frida; Capoccia, Danila; Silecchia, Gianfranco; Di Cristofano, Claudio; Chiappetta, Caterina; Di Domenico, Fabio; Baroni, Marco Giorgio; Perluigi, Marzia; Cavallo, Maria Gisella; Barone, Eugenio - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0925-4439 - wos: WOS:000468708200039 (28) - scopus: 2-s2.0-85062273097 (30)
11573/1335755 - 2019 -
Shining a light on defective autophagy by proteomics approaches: implications for neurodegenerative illnesses Di Domenico, F.; Zuliani, I.; Tramutola, A. - 01a Articolo in rivista
rivista: EXPERT REVIEW OF PROTEOMICS (--London : Expert Reviews Ltd,
London : Future Drugs, 2004-) pp. 1-14 - issn: 1478-9450 - wos: WOS:000496385600001 (8) - scopus: 2-s2.0-85075138357 (10)
11573/1273664 - 2019 -
Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome Di Domenico, Fabio; Tramutola, Antonella; Barone, Eugenio; Lanzillotta, Chiara; Defever, Olivia; Arena, Andrea; Zuliani, Ilaria; Foppoli, Cesira; Iavarone, Federica; Vincenzoni, Federica; Castagnola, Massimo; Butterfield, D Allan; Perluigi, Marzia - 01a Articolo in rivista
rivista: REDOX BIOLOGY (Amsterdam : Elsevier) pp. 101162- - issn: 2213-2317 - wos: WOS:000498848200015 (50) - scopus: 2-s2.0-85062690014 (54)
11573/1244121 - 2019 -
Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease Sharma, Nidhi; Tramutola, Antonella; Lanzillotta, Chiara; Arena, Andrea; Blarzino, Carla; Cassano, Tommaso; Butterfield, D. Allan; Di Domenico, Fabio; Perluigi, Marzia; Barone, Eugenio - 01a Articolo in rivista
rivista: NEUROBIOLOGY OF DISEASE (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 176-189 - issn: 0969-9961 - wos: WOS:000461406000017 (46) - scopus: 2-s2.0-85061254683 (49)
11573/1178992 - 2018 -
Therapeutic potential of rescuing protein O-GlcNAcylation in tau-related pathologies Di Domenico, Fabio; Lanzillotta, Chiara; Tramutola, Antonella - 01a Articolo in rivista
rivista: EXPERT REVIEW OF NEUROTHERAPEUTICS (-London, United Kingdom: Expert Reviews Ltd
-London, United Kingdom: Future Drugs Limited) pp. - - issn: 1473-7175 - wos: WOS:000454507900001 (13) - scopus: 2-s2.0-85055744358 (14)
11573/1456215 - 2018 -
mTOR in Down syndrome: Role in Aß and tau neuropathology and transition to Alzheimer disease-like dementia Di Domenico, Fabio; Tramutola, Antonella; Foppoli, Cesira; Head, Elizabeth; Perluigi, Marzia; Butterfield, D. Allan - 01a Articolo in rivista
rivista: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 94-101 - issn: 0891-5849 - wos: WOS:000418889700011 (64) - scopus: 2-s2.0-85027579851 (70)
11573/1071360 - 2018 -
Early and selective activation and subsequent alterations to the unfolded protein response in down syndrome mouse models Lanzillotta, Chiara; Tramutola, Antonella; Meier, Shelby; Schmitt, Frederick; Barone, Eugenio; Perluigi, Marzia; Di Domenico, Fabio; Abisambra, Jose F - 01a Articolo in rivista
rivista: JOURNAL OF ALZHEIMER'S DISEASE (Netherlands: IOS Press) pp. 347-359 - issn: 1387-2877 - wos: WOS:000424245200026 (18) - scopus: 2-s2.0-85047973196 (18)
11573/1175590 - 2018 -
Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease Tramutola, A; Sharma, N; Barone, E; Lanzillotta, C; Castellani, A; Iavarone, F; Vincenzoni, F; Castagnola, M; Butterfield, Da; Gaetani, S; Cassano, T; Perluigi, M; Di Domenico, F. - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 3309-3321 - issn: 0925-4439 - wos: WOS:000445312000018 (30) - scopus: 2-s2.0-85050225026 (33)
11573/1175577 - 2018 -
Poly-ubiquitin profile in Alzheimer disease brain Tramutola, A; Triani, F; Di Domenico, F; Barone, E; Cai, J; Klein, Jb; Perluigi, M; Butterfield, Da. - 01a Articolo in rivista
rivista: NEUROBIOLOGY OF DISEASE (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 129-141 - issn: 0969-9961 - wos: WOS:000442193400011 (29) - scopus: 2-s2.0-85049878421 (32)
11573/1178983 - 2018 -
Protein nitration profile of CD3+ lymphocytes from Alzheimer disease patients: novel hints on immunosenescence and biomarker detection Tramutola, Antonella; Abate, Giulia; Lanzillotta, Chiara; Triani, Francesca; Barone, Eugenio; Iavarone, Federica; Vincenzoni, Federica; Castagnola, Massimo; Marziano, Mariagrazia; Memo, Maurizio; Garrafa, Emirena; Butterfield, D Allan; Perluigi, Marzia; Di Domenico, Fabio; Uberti, Daniela - 01a Articolo in rivista
rivista: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 430-439 - issn: 0891-5849 - wos: WOS:000450298400039 (21) - scopus: 2-s2.0-85055168925 (21)
11573/1199021 - 2018 -
Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome Tramutola, Antonella; Lanzillotta, Chiara; Barone, Eugenio; Arena, Andrea; Zuliani, Ilaria; Mosca, Luciana; Blarzino, Carla; Butterfield, D. Allan; Perluigi, Marzia; Di Domenico, Fabio - 01a Articolo in rivista
rivista: TRANSLATIONAL NEURODEGENERATION (London : BioMed Central) pp. 1-28 - issn: 2047-9158 - wos: WOS:000449479100001 (72) - scopus: 2-s2.0-85056084092 (79)
11573/1175667 - 2018 -
Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: implications for Alzheimer disease Triani, F; Tramutola, A; Di Domenico, F; Sharma, N; Butterfield, Da; Head, E; Perluigi, M; Barone, E - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 3181-3194 - issn: 0925-4439 - wos: WOS:000445312000007 (38) - scopus: 2-s2.0-85049953122 (41)
11573/935431 - 2017 -
Role of 4-hydroxy-2-nonenal (HNE) in the pathogenesis of Alzheimer disease and other selected age-related neurodegenerative disorders Di Domenico, Fabio; Tramutola, Antonella; Butterfield, D. Allan - 01a Articolo in rivista
rivista: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 253-261 - issn: 0891-5849 - wos: WOS:000406049900022 (189) - scopus: 2-s2.0-85006067115 (200)
11573/1167280 - 2017 -
Multiple Herpes Simplex Virus-1 (HSV-1) reactivations induce neurodegenerative and oxidative damages in mouse brains Fabiani, Marco; Tramutola, Antonella; Napoletani, Giorgia; Perluigi, Marzia; Di Domenico, Fabio; Palamara, Anna Teresa; De Chiara, Giovanna - 04f Poster
congresso: Congresso Nazionale SIM 2017 (Genova)
libro: Congresso Nazionale SIM 2017 – Genova - ()
11573/935443 - 2017 -
Modulation of GLP-1 signaling as a novel therapeutic approach in the treatment of Alzheimer’s disease pathology Tramutola, Antonella; Arena, Andrea; Cini, Chiara; Butterfield, D. Allan; Barone, Eugenio - 01a Articolo in rivista
rivista: EXPERT REVIEW OF NEUROTHERAPEUTICS (-London, United Kingdom: Expert Reviews Ltd
-London, United Kingdom: Future Drugs Limited) pp. 59-75 - issn: 1473-7175 - wos: WOS:000390241300007 (56) - scopus: 2-s2.0-85004024046 (22)
11573/935436 - 2017 -
Polyubiquitinylation profile in down syndrome brain before and after the development of Alzheimer neuropathology Tramutola, Antonella; Di Domenico, Fabio; Barone, Eugenio; Arena, Andrea; Giorgi, Alessandra; Di Francesco, Laura; Schinina', Maria Eugenia; Coccia, Raffaella; Head, Elizabeth; Butterfield, D. Allan; Perluigi, Marzia - 01a Articolo in rivista
rivista: ANTIOXIDANTS & REDOX SIGNALING (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 280-298 - issn: 1523-0864 - wos: WOS:000394334400002 (32) - scopus: 2-s2.0-85013434336 (38)
11573/930567 - 2017 -
Targeting mTOR to reduce Alzheimer-related cognitive decline: from current hits to future therapies Tramutola, Antonella; Lanzillotta, Chiara; Di Domenico, Fabio - 01a Articolo in rivista
rivista: EXPERT REVIEW OF NEUROTHERAPEUTICS (-London, United Kingdom: Expert Reviews Ltd
-London, United Kingdom: Future Drugs Limited) pp. 33-45 - issn: 1473-7175 - wos: WOS:000390241300005 (21) - scopus: 2-s2.0-85004065396 (58)
11573/930564 - 2017 -
Oxidative stress, protein modification and Alzheimer disease Tramutola, Antonella; Lanzillotta, Chiara; Perluigi, Marzia; Butterfield, D. Allan - 01a Articolo in rivista
rivista: BRAIN RESEARCH BULLETIN (Phoenix N.Y.: ANKHO International Inc., c1976-) pp. 88-96 - issn: 0361-9230 - wos: WOS:000410869700010 (206) - scopus: 2-s2.0-84981494654 (221)
11573/846243 - 2016 -
Impairment of biliverdin reductase-a promotes brain insulin resistance in Alzheimer disease: a new paradigm Barone, Eugenio; Di Domenico, Fabio; Cassano, Tommaso; Arena, Andrea; Tramutola, Antonella; Lavecchia, Michele Angelo; Coccia, Raffaella; Butterfield, D. Allan; Perluigi, Marzia - 01a Articolo in rivista
rivista: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 127-142 - issn: 0891-5849 - wos: WOS:000370181400012 (90) - scopus: 2-s2.0-84950335909 (93)
11573/1023555 - 2016 -
Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients Di Domenico, Fabio; Pupo, Gilda; Giraldo, Esther; Badã¬A, Mari-Carmen; Monllor, Paloma; Lloret, Ana; Eugenia Schininã&Nbsp;, Maria; Giorgi, Alessandra; Cini, Chiara; Tramutola, Antonella; Butterfield, D. Allan; Viã±A, Josã©; Perluigi, Marzia - 01a Articolo in rivista
rivista: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 1-9 - issn: 0891-5849 - wos: WOS:000370181400001 (79) - scopus: 2-s2.0-84949509857 (84)
11573/935430 - 2016 -
Cathepsin D as a therapeutic target in Alzheimer’s disease Di Domenico, Fabio; Tramutola, Antonella; Perluigi, Marzia - 01a Articolo in rivista
rivista: EXPERT OPINION ON THERAPEUTIC TARGETS (--London United Kingdom:Informa Healthcare
-London : Ashley, 2002-.) pp. 1393-1395 - issn: 1472-8222 - wos: WOS:000388696200001 (38) - scopus: 2-s2.0-84994085585 (42)
11573/871573 - 2016 -
It is all about (U)biquitin: role of altered ubiquitin-proteasome system and UCHL1 in Alzheimer disease Tramutola, Antonella; Di Domenico, Fabio; Barone, Eugenio; Perluigi, Marzia; Butterfield, David Allan - 01a Articolo in rivista
rivista: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (London: Hindawi
AUSTIN, USA, TX: LANDES BIOSCIENCE) pp. - - issn: 1942-0900 - wos: WOS:000372640600001 (81) - scopus: 2-s2.0-84961344015 (82)
11573/840612 - 2016 -
Increased mammalian target of rapamycin signaling contributes to the accumulation of protein oxidative damage in a mouse model of down's syndrome Tramutola, Antonella; Lanzillotta, Chiara; Arena, Andrea; Barone, Eugenio; Perluigi, Marzia; Di Domenico, Fabio - 01a Articolo in rivista
rivista: NEURODEGENERATIVE DISEASES (Basel [etc.]: S. Karger 2004-) pp. 62-68 - issn: 1660-2854 - wos: WOS:000369778000010 (34) - scopus: 2-s2.0-84958063630 (35)
11573/867882 - 2016 -
Activation of p53 in down syndrome and in the ts65dn mouse brain is associated with a pro-apoptotic phenotype Tramutola, Antonella; Pupo, Gilda; Di Domenico, Fabio; Barone, Eugenio; Arena, Andrea; Lanzillotta, Chiara; Broekaart, Diede; Blarzino, Carla; Head, Elizabeth; Butterfield, D. Allan; Perluigi, Marzia - 01a Articolo in rivista
rivista: JOURNAL OF ALZHEIMER'S DISEASE (Netherlands: IOS Press) pp. 359-71-371 - issn: 1387-2877 - wos: WOS:000375008500030 (26) - scopus: 2-s2.0-84973143959 (30)
11573/796567 - 2015 -
Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD Tramutola, Antonella; Triplett, Judy C.; Di Domenico, Fabio; Niedowicz, Dana M.; Murphy, Michael P.; Coccia, Raffaella; Perluigi, Marzia; Butterfield, D. Allan - 01a Articolo in rivista
rivista: JOURNAL OF NEUROCHEMISTRY (Editore attuale:BLACKWELL PUBLISHING LTD, 9600 GARSINGTON RD, OXFORD, ENGLAND, OXON, OX4 2DG
Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320) pp. 739-749 - issn: 0022-3042 - wos: WOS:000353570500012 (251) - scopus: 2-s2.0-84928012290 (266)
11573/871576 - 2015 -
Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity. Triplett, Jc; Tramutola, Antonella; Swomley, A; Kirk, J; Grimes, K; Lewis, K; Orr, M; Rodriguez, K; Cai, J; Klein, Jb; Perluigi, Marzia; Buffenstein, R; Butterfield, D. A. - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0006-3002 - wos: WOS:000361924700021 (49) - scopus: 2-s2.0-84939431103 (53)
11573/556923 - 2014 -
Redox proteomics analysis of HNE-modified proteins in Down syndrome brain: clues for understanding the development of Alzheimer disease. Di Domenico, Fabio; Pupo, Gilda; Tramutola, Antonella; Giorgi, Alessandra; Schinina', Maria Eugenia; Coccia, Raffaella; E., Head; D. A., Butterfield; Perluigi, Marzia - 01a Articolo in rivista
rivista: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 270-280 - issn: 0891-5849 - wos: WOS:000336891100024 (82) - scopus: 2-s2.0-84898812067 (89)
11573/871580 - 2014 -
Antiretroviral agents increase
NO production in gp120/IFNγ-stimulated cultures of rat microglia via an
arginase-dependent mechanism. Lisi, L; Tramutola, Antonella; Navarra, P; Dello Russo, C. - 01a Articolo in rivista
rivista: JOURNAL OF NEUROIMMUNOLOGY (Amsterdam ; Lausanne ; New York ; Oxford ; Shannon ; Tokyo : Elsevier) pp. - - issn: 0165-5728 - wos: WOS:000331021700003 (14) - scopus: 2-s2.0-84891482258 (15)
11573/556926 - 2014 -
Neuropathological role of pi3k/akt/mtor axis in Down syndrome brain Perluigi, Marzia; Pupo, Gilda; Tramutola, Antonella; Cini, Chiara; Coccia, Raffaella; Barone, Eugenio; E., Head; D. A., Butterfield; Di Domenico, Fabio - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1144-1153 - issn: 0925-4439 - wos: WOS:000336698400027 (126) - scopus: 2-s2.0-84899787783 (133)
11573/540205 - 2013 -
Pathological role of PI3K/AKT/mTOR signaling pathway in Down Syndrome brain Pupo, Gilda; Tramutola, Antonella; C., Foppoli; Di Domenico, Fabio - 04a Atto di comunicazione a congresso
congresso: 57th National Meeting of the Italian Society of Biochemistry and Molecular Biology (SIB) (Ferrara)
11573/509451 - 2013 -
Transplacental Exposure to AZT Induces Adverse Neurochemical and Behavioral Effects in a Mouse Model: Protection by L-Acetylcarnitine Zuena, Anna Rita; Giuli, Chiara; Aldina Venerosi, Pesciolini; Tramutola, Antonella; Maria Antonietta Ajmone, Cat; Cinque, Carlo; Alema', Giovanni Sebastiano; Angela, Giovine; Gianfranco, Peluso; Luisa, Minghetti; Raffaella, Nicolai; Gemma, Calamandrei; Casolini, Paola - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e55753- - issn: 1932-6203 - wos: WOS:000315157200060 (11) - scopus: 2-s2.0-84873603174 (14)
11573/485911 - 2012 -
Relocation stress induced long-term fecal hormonal modifications in semi free-ranging social groups of Macaca tonkeana Cinque, Carlo; Casolini, Paola; Catalani, Assia; De Marco, A.; De Marco, L.; Giuli, Chiara; Mairesse, J.; Sanna, A.; Stacchini, P.; Thierry, B.; Tramutola, Antonella; Zinni, Manuela; Zuena, Anna Rita; Cozzolino, R. - 04c Atto di convegno in rivista
rivista: WIENER TIERARZTLICHE MONATSSCHRIFT (Bwk Zentrale Und Verlag:Grossmannstrasse 30, A 1220 Vienna Austria:011 43 1 7747094, EMAIL: office@bwk.at, INTERNET: http://www.bwk.at, Fax: 011 43 1 7747095) pp. 50-50 - issn: 0253-9411 - wos: (0) - scopus: (0)
11573/493166 - 2012 -
Maternal exposure to low levels of corticosterone during lactation increases social play behavior in rat adolescent offspring Cinque, Carlo; Zuena, Anna Rita; Catalani, Assia; Giuli, Chiara; Tramutola, Antonella; Scaccianoce, Sergio - 01a Articolo in rivista
rivista: REVIEWS IN THE NEUROSCIENCES (Berlin; Boston: de Gruyter
Freund Publishing House Limited) pp. 723-730 - issn: 0334-1763 - wos: WOS:000314456900022 (3) - scopus: 2-s2.0-84869459565 (3)
11573/871583 - 2012 -
Modulatory effects
of the CCR5 antagonist maraviroc on microglial pro-inflammatory activation
elicited by gp120. Lisi, L; Tramutola, Antonella; De Luca, A; Navarra, P; Dello Russo, C. - 01a Articolo in rivista
rivista: JOURNAL OF NEUROCHEMISTRY (Oxford : Blackwell) pp. - - issn: 1471-4159 - wos: WOS:000298060500011 (34) - scopus: 2-s2.0-83855165646 (33)
11573/871592 - 2011 -
Trigeminal satellite cells express functional calcitonin gene-related
peptide receptors, whose activation enhances interleukin-1β pro-inflammatory
effects. De Corato, A; Lisi, L; Capuano, A; Tringali, G; Tramutola, Antonella; Navarra, P; Dello Russo, C. - 01a Articolo in rivista
rivista: JOURNAL OF NEUROIMMUNOLOGY (Amsterdam ; Lausanne ; New York ; Oxford ; Shannon ; Tokyo : Elsevier) pp. - - issn: 0165-5728 - wos: WOS:000294933800006 (36) - scopus: 2-s2.0-80051470137 (38)