11573/1701072 - 2024 -
Identification of the pyridoxal 5′‐phosphate allosteric site in human pyridox(am)ine 5′‐phosphate oxidase Barile, Anna; Graziani, Claudio; Antonelli, Lorenzo; Parroni, Alessia; Fiorillo, Annarita; Di Salvo, Martino Luigi; Ilari, Andrea; Giorgi, Alessandra; Rosignoli, Serena; Paiardini, Alessandro; Contestabile, Roberto; Tramonti, Angela - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:001146773300001 (2) - scopus: 2-s2.0-85182849034 (2)
11573/1719527 - 2024 -
Sorcin in Cancer Development and Chemotherapeutic Drug Resistance Exertier, Cécile; Antonelli, Lorenzo; Fiorillo, Annarita; Bernardini, Roberta; Colotti, Beatrice; Ilari, Andrea; Colotti, Gianni - 01g Articolo di rassegna (Review)
rivista: CANCERS (Basel: MDPI) pp. 1-20 - issn: 2072-6694 - wos: WOS:001305010600001 (0) - scopus: 2-s2.0-85202531499 (0)
11573/1702597 - 2024 -
Fragment merging, growing, and linking identify new trypanothione reductase inhibitors for Leishmaniasis Exertier, Cécile; Salerno, Alessandra; Antonelli, Lorenzo; Fiorillo, Annarita; Ocello, Riccardo; Seghetti, Francesca; Caciolla, Jessica; Uliassi, Elisa; Masetti, Matteo; Fiorentino, Eleonora; Orsini, Stefania; Di Muccio, Trentina; Ilari, Andrea; Bolognesi, Maria Laura - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 402-419 - issn: 0022-2623 - wos: WOS:001141765500001 (1) - scopus: 2-s2.0-85181572632 (1)
11573/1719569 - 2024 -
The Z isomer of pyridoxilidenerhodanine 5′‐phosphate is an efficient inhibitor of human pyridoxine 5′‐phosphate oxidase, a crucial enzyme in vitamin B6 salvage pathway and a potential chemotherapeutic target Graziani, Claudio; Barile, Anna; Antonelli, Lorenzo; Fiorillo, Annarita; Ilari, Andrea; Vetica, Fabrizio; Di Salvo, Martino Luigi; Paiardini, Alessandro; Tramonti, Angela; Contestabile, Roberto - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. - - issn: 1742-464X - wos: (0) - scopus: 2-s2.0-85204241869 (0)
11573/1719535 - 2024 -
AI is a viable alternative to high throughput screening: a 318-target study Null, Null; Wallach, Izhar; Bernard, Denzil; Nguyen, Kong; Ho, Gregory; Morrison, Adrian; Stecula, Adrian; Rosnik, Andreana; O'sullivan, Ann Marie; Davtyan, Aram; Samudio, Ben; Thomas, Bill; Worley, Brad; Butler, Brittany; Laggner, Christian; Thayer, Desiree; Moharreri, Ehsan; Friedland, Greg; Truong, Ha; Van Den Bedem, Henry; Ng, Ho Leung; Stafford, Kate; Sarangapani, Krishna; Giesler, Kyle; Ngo, Lien; Mysinger, Michael; Ahmed, Mostafa; Anthis, Nicholas J.; Henriksen, Niel; Gniewek, Pawel; Eckert, Sam; De Oliveira, Saulo; Suterwala, Shabbir; Prasadprasad, Srimukh Veccham Krishna; Shek, Stefani; Contreras, Stephanie; Hare, Stephanie; Palazzo, Teresa; O'brien, Terrence E.; Van Grack, Tessa; Williams, Tiffany; Chern, Ting-Rong; Kenyon, Victor; Lee, Andreia H.; Cann, Andrew B.; Bergman, Bastiaan; Anderson, Brandon M.; Cox, Bryan D.; Warrington, Jeffrey M.; Sorenson, Jon M.; Goldenberg, Joshua M.; Young, Matthew A.; Dehaan, Nicholas; Pemberton, Ryan P.; Schroedl, Stefan; Abramyan, Tigran M.; Gupta, Tushita; Mysore, Venkatesh; Presser, Adam G.; Ferrando, Adolfo A.; Andricopulo, Adriano D.; Ghosh, Agnidipta; Ayachi, Aicha Gharbi; Mushtaq, Aisha; Shaqra, Ala M.; Toh, Alan Kie Leong; Smrcka, Alan V.; Ciccia, Alberto; De Oliveira, Aldo Sena; Sverzhinsky, Aleksandr; De Sousa, Alessandra Mara; Agoulnik, Alexander I.; Kushnir, Alexander; Freiberg, Alexander N.; Statsyuk, Alexander V.; Gingras, Alexandre R.; Degterev, Alexei; Tomilov, Alexey; Vrielink, Alice; Garaeva, Alisa A.; Bryant-Friedrich, Amanda; Caflisch, Amedeo; Patel, Amit K.; Rangarajan, Amith Vikram; Matheeussen, An; Battistoni, Andrea; Caporali, Andrea; Chini, Andrea; Ilari, Andrea; Mattevi, Andrea; Foote, Andrea Talbot; Trabocchi, Andrea; Stahl, Andreas; Herr, Andrew B.; Berti, Andrew; Freywald, Andrew; Reidenbach, Andrew G.; Lam, Andrew; Cuddihy, Andrew R.; White, Andrew; Taglialatela, Angelo; Ojha, Anil K.; Cathcart, Ann M.; Motyl, Anna A. L.; Borowska, Anna; D'antuono, Anna; Hirsch, Anna K. H.; Porcelli, Anna Maria; Minakova, Anna; Montanaro, Anna; Müller, Anna; Fiorillo, Annarita; Virtanen, Anniina; O'donoghue, Anthony J.; Del Rio Flores, Antonio; Garmendia, Antonio E.; Pineda-Lucena, Antonio; Panganiban, Antonito T.; Samantha, Ariela; Chatterjee, Arnab K.; Haas, Arthur L.; Paparella, Ashleigh S.; John, Ashley L. St.; Prince, Ashutosh; Elsheikh, Assmaa; Apfel, Athena Marie; Colomba, Audrey; O'dea, Austin; Diallo, Bakary N'tji; Ribeiro, Beatriz Murta Rezende Moraes; Bailey-Elkin, Ben A.; Edelman, Benjamin L.; Liou, Benjamin; Perry, Benjamin; Chua, Benjamin Soon Kai; Kováts, Benjámin; Englinger, Bernhard; Balakrishnan, Bijina; Gong, Bin; Agianian, Bogos; Pressly, Brandon; Salas, Brenda P. Medellin; Duggan, Brendan M.; Geisbrecht, Brian V.; Dymock, Brian W.; Morten, Brianna C.; Hammock, Bruce D.; Mota, Bruno Eduardo Fernandes; Dickinson, Bryan C.; Fraser, Cameron; Lempicki, Camille; Novina, Carl D.; Torner, Carles; Ballatore, Carlo; Bon, Carlotta; Chapman, Carly J.; Partch, Carrie L.; Chaton, Catherine T.; Huang, Chang; Yang, Chao-Yie; Kahler, Charlene M.; Karan, Charles; Keller, Charles; Dieck, Chelsea L.; Huimei, Chen; Liu, Chen; Peltier, Cheryl; Mantri, Chinmay Kumar; Kemet, Chinyere Maat; Müller, Christa E.; Weber, Christian; Zeina, Christina M.; Muli, Christine S.; Morisseau, Christophe; Alkan, Cigdem; Reglero, Clara; Loy, Cody A.; Wilson, Cornelia M.; Myhr, Courtney; Arrigoni, Cristina; Paulino, Cristina; Santiago, César; Luo, Dahai; Tumes, Damon J.; Keedy, Daniel A.; Lawrence, Daniel A.; Chen, Daniel; Manor, Danny; Trader, Darci J.; Hildeman, David A.; Drewry, David H.; Dowling, David J.; Hosfield, David J.; Smith, David M.; Moreira, David; Siderovski, David P.; Shum, David; Krist, David T.; Riches, David W. H.; Ferraris, Davide Maria; Anderson, Deborah H.; Coombe, Deirdre R.; Welsbie, Derek S.; Hu, Di; Ortiz, Diana; Alramadhani, Dina; Zhang, Dingqiang; Chaudhuri, Dipayan; Slotboom, Dirk J.; Ronning, Donald R.; Lee, Do - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature
London: Nature Publishing Group) pp. 1-16 - issn: 2045-2322 - wos: WOS:001253148000001 (17) - scopus: 2-s2.0-85191821387 (19)
11573/1683483 - 2023 -
Investigation of the entry pathway and molecular nature of σ1 receptor ligands Pascarella, Gianmarco; Antonelli, Lorenzo; Narzi, Daniele; Battista, Theo; Fiorillo, Annarita; Colotti, Gianni; Guidoni, Leonardo; Morea, Veronica; Ilari, Andrea - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 6367- - issn: 1422-0067 - wos: WOS:000969918600001 (2) - scopus: 2-s2.0-85152800395 (2)
11573/1669499 - 2022 -
Optimization of potent and specific trypanothione reductase inhibitors. A structure-based drug discovery approach Battista, T.; Federico, S.; Brogi, S.; Pozzetti, L.; Khan, T.; Butini, S.; Ramunno, A.; Fiorentino, E.; Orsini, S.; Di Muccio, T.; Fiorillo, A.; Exertier, C.; Di Risola, D.; Colotti, G.; Gemma, S.; Ilari, A.; Campiani, G. - 01a Articolo in rivista
rivista: ACS INFECTIOUS DISEASES (Washington, DC : American Chemical Society, 2015-) pp. 1687-1699 - issn: 2373-8227 - wos: WOS:000841968500001 (5) - scopus: 2-s2.0-85136100094 (6)
11573/1669731 - 2022 -
Innovative approach for a classic target: fragment screening on trypanothione reductase reveals new opportunities for drug design Fiorillo, A; Colotti, G; Exertier, C; Liuzzi, A; Seghetti, F; Salerno, A; Caciolla, J; Ilari, Andrea - 01a Articolo in rivista
rivista: FRONTIERS IN MOLECULAR BIOSCIENCES (Lausanne : Frontiers Media S.A., 2014-) pp. 900882- - issn: 2296-889X - wos: WOS:000840902100001 (5) - scopus: 2-s2.0-85134362862 (5)
11573/1554277 - 2021 -
Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase Barile, Anna; Battista, Theo; Fiorillo, Annarita; Luigi Di Salvo, Martino; Malatesta, Francesco; Tramonti, Angela; Ilari, Andrea; Contestabile, Roberto - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 1-16 - issn: 0021-9258 - wos: WOS:000674717300015 (9) - scopus: 2-s2.0-85108156162 (10)
11573/1490593 - 2021 -
Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells Battista, T.; Pascarella, G.; Staid, D. S.; Colotti, G.; Rosati, J.; Fiorillo, A.; Casamassa, A.; Vescovi, A. L.; Giabbai, B.; Semrau, M. S.; Fanelli, S.; Storici, P.; Squitieri, F.; Morea, V.; Ilari, A. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 1-26 - issn: 1661-6596 - wos: WOS:000615316700001 (6) - scopus: 2-s2.0-85099932913 (6)
11573/1609024 - 2021 -
Structure and metal-binding properties of PA4063, a novel player in periplasmic zinc trafficking by Pseudomonas aeruginosa Fiorillo, A.; Battistoni, A.; Ammendola, S.; Secli, V.; Rinaldo, S.; Cutruzzola, F.; Demitri, N.; Ilari, A. - 01a Articolo in rivista
rivista: ACTA CRYSTALLOGRAPHICA. SECTION D, STRUCTURAL BIOLOGY (Chester : International Union of Crystallography, 2016-) pp. 1401-1410 - issn: 2059-7983 - wos: WOS:000714429000007 (6) - scopus: 2-s2.0-85118921269 (6)
11573/1617233 - 2021 -
Huntingtin ubiquitination mechanisms and novel possible therapies to decrease the toxic effects of mutated huntingtin Fiorillo, A.; Morea, V.; Colotti, G.; Ilari, A. - 01a Articolo in rivista
rivista: JOURNAL OF PERSONALIZED MEDICINE (Basel: MDPI AG, 2011-) pp. 1309- - issn: 2075-4426 - wos: WOS:000738237500001 (7) - scopus: 2-s2.0-85121616450 (7)
11573/1622657 - 2021 -
Re-discovery of giardiavirus: Genomic and functional analysis of viruses from giardia duodenalis isolates Marucci, G.; Zullino, I.; Bertuccini, L.; Camerini, S.; Cecchetti, S.; Pietrantoni, A.; Casella, M.; Vatta, P.; Greenwood, A. D.; Fiorillo, A.; Lalle, M. - 01a Articolo in rivista
rivista: BIOMEDICINES (Basel: MDPI) pp. 654- - issn: 2227-9059 - wos: WOS:000665367900001 (1) - scopus: 2-s2.0-85108567951 (1)
11573/1467188 - 2020 -
Targeting trypanothione reductase, a key enzyme in the redox trypanosomatid metabolism, to develop new drugs against leishmaniasis and trypanosomiases Battista, T.; Colotti, G.; Ilari, A.; Fiorillo, A. - 01a Articolo in rivista
rivista: MOLECULES (Basel: MDPI
Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:000534617500073 (32) - scopus: 2-s2.0-85083798823 (37)
11573/1467192 - 2020 -
Roles of sorcin in drug resistance in cancer: one protein, many mechanisms, for a novel potential anticancer drug target Battista, T.; Fiorillo, A.; Chiarini, V.; Genovese, I.; Ilari, A.; Colotti, G. - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000535587400116 (31) - scopus: 2-s2.0-85083296641 (30)
11573/1467178 - 2020 -
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome Genovese, I.; Carotti, A.; Ilari, A.; Fiorillo, A.; Battista, T.; Colotti, G.; Ivarsson, Y. - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0304-4165 - wos: WOS:000536757900011 (5) - scopus: 2-s2.0-85083506091 (5)
11573/1446209 - 2020 -
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases Genovese, I.; Giamogante, F.; Barazzuol, L.; Battista, T.; Fiorillo, A.; Vicario, M.; D'alessandro, G.; Cipriani, R.; Limatola, C.; Rossi, D.; Sorrentino, V.; Poser, E.; Mosca, L.; Squitieri, F.; Perluigi, M.; Arena, A.; Van Petegem, F.; Tito, C.; Fazi, F.; Giorgi, C.; Cali, T.; Ilari, A.; Colotti, G. - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. 1-18 - issn: 2041-4889 - wos: WOS:000581611700003 (31) - scopus: 2-s2.0-85092570946 (31)
11573/1467182 - 2020 -
Spiro-containing derivatives show antiparasitic activity against trypanosoma brucei through inhibition of the trypanothione reductase enzyme Turcano, L.; Battista, T.; De Haro, E. T.; Missineo, A.; Alli, C.; Paonessa, G.; Colotti, G.; Harper, S.; Fiorillo, A.; Ilari, A.; Bresciani, A. - 01a Articolo in rivista
rivista: PLOS NEGLECTED TROPICAL DISEASES (San Francisco, CA : Public Library of Science) pp. 1-17 - issn: 1935-2727 - wos: WOS:000558076200066 (12) - scopus: 2-s2.0-85083783860 (15)
11573/1336764 - 2019 -
Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism Colotti, G.; Saccoliti, F.; Gramiccia, M.; Di Muccio, T.; Prakash, J.; Yadav, S.; Dubey, V. K.; Vistoli, G.; Battista, T.; Mocci, S.; Fiorillo, A.; Bibi, Aasia; Madia, V. N.; Messore, A.; Costi, R.; Di Santo, R.; Ilari, A. - 01a Articolo in rivista
rivista: AMINO ACIDS (Wien: Springer Verlag) pp. - - issn: 0939-4451 - wos: WOS:000519385700013 (15) - scopus: 2-s2.0-85065106515 (16)
11573/1071675 - 2018 -
Study of manganese binding to the ferroxidase centre of human H-type ferritin Ardini, Matteo; Howes, Barry D; Fiorillo, Annarita; Falvo, Elisabetta; Sottini, Silvia; Rovai, Donella; Lantieri, Marco; Ilari, Andrea; Gatteschi, Dante; Spina, Gabriele; Chiancone, Emilia; Stefanini, Simonetta; Fittipaldi, Maria - 01a Articolo in rivista
rivista: JOURNAL OF INORGANIC BIOCHEMISTRY (Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680) pp. 103-112-112 - issn: 0162-0134 - wos: WOS:000430157000011 (14) - scopus: 2-s2.0-85042111897 (14)
11573/1071661 - 2018 -
Metal- and metalloid-containing drugs for the treatment of trypanosomatid diseases Colotti, Gianni; Fiorillo, Annarita; Ilari, Andrea - 01a Articolo in rivista
rivista: FRONTIERS IN BIOSCIENCE () pp. 954-966- - issn: 1093-4715 - wos: WOS:000439041000012 (10) - scopus: 2-s2.0-85047304238 (11)
11573/1128941 - 2018 -
The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme Fiorillo, Annarita; Petrosino, Maria; Ilari, Andrea; Pasquo, Alessandra; Cipollone, Alessandra; Maggi, Maristella; Chiaraluce, Roberta; Consalvi, Valerio - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. - - issn: 1932-6203 - wos: WOS:000438388800019 (16) - scopus: 2-s2.0-85049668585 (19)
11573/1279160 - 2018 -
Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents Genovese, Ilaria; Ilari, Andrea; Battista, Theo; Chiarini, Valerio; Fazi, Francesco; Fiorillo, Annarita; Colotti, Gianni - 01a Articolo in rivista
rivista: CANCER DRUG RESISTANCE (Alhambra CA: OAE Publishing Inc., 2018-) pp. - - issn: 2578-532X - wos: WOS:000848677200004 (9) - scopus: 2-s2.0-85066132614 (9)
11573/1175786 - 2018 -
Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors Ilari, Andrea; Genovese, Ilaria; Fabiana, Fiorillo; Battista, Theo; Ilenia De Ionna, ; Fiorillo, Annarita; Colotti, Gianni - 01a Articolo in rivista
rivista: MOLECULAR PHARMACEUTICS (Washington, DC : American Chemical Society, c2004-) pp. 3069-3078 - issn: 1543-8384 - wos: WOS:000441476800020 (15) - scopus: 2-s2.0-85048727260 (16)
11573/955132 - 2017 -
Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX Brogi, Simone; Fiorillo, Annarita; Chemi, Giulia; Butini, Stefania; Lalle, Marco; Ilari, Andrea; Gemma, Sandra; Campiani, Giuseppe - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 479-490-490 - issn: 0223-5234 - wos: WOS:000403512100039 (35) - scopus: 2-s2.0-85018947771 (36)
11573/1011187 - 2017 -
Binding of doxorubicin to sorcin impairs cell death and increases drug resistance in cancer cells Genovese, Ilaria; Fiorillo, Annarita; Ilari, Andrea; Masciarelli, Silvia; Fazi, Francesco; Colotti, Gianni - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. 1-9 - issn: 2041-4889 - wos: WOS:000406870400039 (46) - scopus: 2-s2.0-85032698221 (46)
11573/1015062 - 2017 -
An update on structural insights into the enzymes of the polyamine-trypanothione pathway: Targets for new drugs against leishmaniasis Ilari, Andrea; Fiorillo, Annarita; Genovese, Ilaria; Colotti, Gianni - 01a Articolo in rivista
rivista: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 61-77 - issn: 1756-8919 - wos: WOS:000391868200005 (45) - scopus: 2-s2.0-85008204118 (48)
11573/1015058 - 2017 -
Glucose transportation in the brain and its impairment in Huntington disease: one more shade of the energetic metabolism failure? Morea, Veronica; Bidollari, Eris; Colotti, Gianni; Fiorillo, Annarita; Rosati, Jessica Diana; De Filippis, Lidia; Squitieri, Ferdinando; Ilari, Andrea - 01a Articolo in rivista
rivista: AMINO ACIDS (Wien: Springer Verlag) pp. 1147-1157 - issn: 0939-4451 - wos: WOS:000403661400001 (21) - scopus: 2-s2.0-85017230931 (23)
11573/929856 - 2017 -
Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives Saccoliti, Francesco; Angiulli, Gabriella; Pupo, Giovanni; Pescatori, Luca; Madia, Valentina Noemi; Messore, Antonella; Colotti, Gianni; Fiorillo, Annarita; Scipione, Luigi; Gramiccia, Marina; Di Muccio, Trentina; Di Santo, Roberto; Costi, Roberta; Ilari, Andrea - 01a Articolo in rivista
rivista: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 304-310 - issn: 1475-6366 - wos: WOS:000392591100025 (48) - scopus: 2-s2.0-85013797723 (54)
11573/844659 - 2016 -
Short peptides from leucyl-tRNA synthetase rescue disease-causing mitochondrial tRNA point mutations Perli, Elena; Fiorillo, Annarita; Giordano, Carla; Pisano, Annalinda; Montanari, Arianna; Grazioli, Paola; Campese, Antonio Francesco; Di Micco, Patrizio; Tuppen, Helen A; Genovese, Ilaria; Poser, Elena; Preziuso, Carmela; Taylor, Robert W; Morea, Veronica; Colotti, Gianni; D'amati, Giulia - 01a Articolo in rivista
rivista: HUMAN MOLECULAR GENETICS (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 903-915 - issn: 0964-6906 - wos: WOS:000372152400006 (19) - scopus: 2-s2.0-84962834087 (20)
11573/850742 - 2015 -
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking Brindisi, Margherita; Brogi, Simone; Relitti, Nicola; Vallone, Alessandra; Butini, Stefania; Gemma, Sandra; Novellino, Ettore; Colotti, Gianni; Angiulli, Gabriella; Di Chiaro, Francesco; Fiorillo, Annarita; Ilari, Andrea; Campiani, Giuseppe - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature
London: Nature Publishing Group) pp. 9705- - issn: 2045-2322 - wos: WOS:000354108100001 (57) - scopus: 2-s2.0-84929000082 (63)
11573/1016272 - 2015 -
Molecular Dynamics Simulations and Structural Analysis of Giardia duodenalis 14-3-3 Protein-Protein Interactions Cau, Ylenia; Fiorillo, Annarita; Mori, Mattia; Ilari, Andrea; Botta, Maurizo; Lalle, Marco - 01a Articolo in rivista
rivista: JOURNAL OF CHEMICAL INFORMATION AND MODELING (AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036) pp. 2611-2622 - issn: 1549-9596 - wos: WOS:000367560200013 (15) - scopus: 2-s2.0-84952776156 (18)
11573/850750 - 2015 -
Targeting polyamine metabolism for finding new drugs against leishmaniasis: a review Ilari, Andrea; Fiorillo, Annarita; Baiocco, Paola; Poser, Elena; Angiulli, Gabriella; Colotti, Gianni - 01a Articolo in rivista
rivista: MINI-REVIEWS IN MEDICINAL CHEMISTRY (Hilversum : Bentham Science Publishers) pp. 243-52- - issn: 1875-5607 - wos: WOS:000352094500007 (29) - scopus: 2-s2.0-84930985930 (34)
11573/850705 - 2015 -
Structural basis of Sorcin-mediated calcium-dependent signal transduction Ilari, Andrea; Fiorillo, Annarita; Poser, Elena; Lalioti, Vasiliki S.; Sundell, Gustav N.; Ivarsson, Ylva; Genovese, Ilaria; Colotti, Gianni - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature
London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000364903100002 (43) - scopus: 2-s2.0-84947251829 (47)
11573/1016263 - 2014 -
Sorcin, a calcium binding protein involved in the multidrug resistance mechanisms in cancer cells Colotti, Gianni; Poser, Elena; Fiorillo, Annarita; Genovese, Ilaria; Chiarini, Valerio; Ilari, Andrea - 01a Articolo in rivista
rivista: MOLECULES (Basel: MDPI
Berlin: Springer, 1996-) pp. 13976-13989 - issn: 1420-3049 - wos: WOS:000343093100066 (57) - scopus: 2-s2.0-84907101340 (58)
11573/836215 - 2014 -
The crystal structure of Giardia duodenalis 14-3-3 in the apo form: When protein post-translational modifications make the difference Fiorillo, Annarita; Di Marino, Daniele; Bertuccini, Lucia; Via, Allegra; Pozio, Edoardo; Camerini, Serena; Ilari, Andrea; Lalle, Marco - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e92902- - issn: 1932-6203 - wos: WOS:000333355300143 (10) - scopus: 2-s2.0-84899072734 (12)
11573/1016136 - 2013 -
Kineococcus radiotolerans Dps forms a heteronuclear Mn-Fe ferroxidase center that may explain the Mn-dependent protection against oxidative stress Ardini, Matteo; Fiorillo, Annarita; Fittipaldi, Maria; Stefanini, Simonetta; Gatteschi, Dante; Ilari, Andrea; Chiancone, Emilia - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 3745-3755 - issn: 0304-4165 - wos: WOS:000319232400043 (24) - scopus: 2-s2.0-84875984007 (25)
11573/523394 - 2013 -
Inhibition of Leishmania infantum trypanothione reductase by azole-based compounds: a comparative analysis with its physiological substrate by X-ray crystallography Baiocco, P.; Poce, Giovanna; Alfonso, Salvatore; Cocozza, Martina; Porretta, Giulio Cesare; Colotti, G.; Biava, Mariangela; Moraca, F.; Botta, M.; Yardley, V.; Fiorillo, A.; Lantella, A.; Malatesta, Francesco; Ilari, Andrea - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1175-1183 - issn: 1860-7179 - wos: WOS:000320928400012 (57) - scopus: 2-s2.0-84879786172 (62)
11573/1016141 - 2013 -
Metal-based compounds as prospective antileishmanial agents: Inhibition of Trypanothione reductase by selected gold complexes Colotti, Gianni; Ilari, Andrea; Fiorillo, Annarita; Baiocco, Paola; Cinellu, Maria Agostina; Maiore, Laura; Scaletti, Federica; Gabbiani, Chiara; Messori, Luigi - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1634-1637 - issn: 1860-7179 - wos: WOS:000325137800011 (32) - scopus: 2-s2.0-84884973403 (36)
11573/506997 - 2012 -
The crystal structures of
the tryparedoxin-tryparedoxin peroxidase couple unveil the structural
determinants of Leishmania detoxification pathway. Fiorillo, Annarita; Colotti, G; Boffi, Alberto; Baiocco, Paola; Ilari, Andrea - 01a Articolo in rivista
rivista: PLOS NEGLECTED TROPICAL DISEASES (San Francisco, CA : Public Library of Science) pp. - - issn: 1935-2735 - wos: WOS:000308497100021 (43) - scopus: 2-s2.0-84865996192 (47)
11573/515791 - 2012 -
A gold-containing drug against parasitic polyamine metabolism: the
X-ray structure of trypanothione reductase from Leishmania infantum in complex
with auranofin reveals a dual mechanism of enzyme inhibition. Ilari, Andrea; Baiocco, P; Messori, L; Fiorillo, Annarita; Boffi, Alberto; Gramiccia, M; Di Muccio, T; Colotti, G. - 01a Articolo in rivista
rivista: AMINO ACIDS (Wien: Springer.) pp. 803-811 - issn: 1438-2199 - wos: WOS:000299506000039 (133) - scopus: 2-s2.0-84861660490 (146)
11573/120031 - 2011 -
The structure of maize polyamine oxidase K300M mutant in complex with the natural substrates provides a snapshot of the catalytic mechanism of polyamine oxidation Fiorillo, Annarita; Federico, Rodolfo; Fabio, Polticelli; Boffi, Alberto; Mazzei, Franco; Di Fusco, Massimo; Ilari, Andrea; Paraskevi, Tavladoraki - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 809-821 - issn: 1742-464X - wos: WOS:000287448800011 (16) - scopus: 2-s2.0-79951950697 (16)
11573/338831 - 2010 -
Silver Ion Incorporation and Nanoparticle Formation inside the Cavity of Pyrococcus furiosus Ferritin: Structural and Size-Distribution Analyses Oksana, Kasyutich; Ilari, Andrea; Fiorillo, Annarita; Dragomir, Tatchev; Armin, Hoell; Ceci, Pierpaolo - 01a Articolo in rivista
rivista: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ([Washington, USA: American Chemical Society] 1879-) pp. 3621-3627 - issn: 0002-7863 - wos: WOS:000275660600064 (107) - scopus: 2-s2.0-77949400142 (108)
11573/365100 - 2009 -
Crystal structure of a family 16 endoglucanase from the hyperthermophile Pyrococcus furiosus- structural basis of substrate recognition. Ilari, Andrea; Fiorillo, A; Angelaccio, Sebastiana; Florio, Rita; Chiaraluce, Roberta; Van Der Oost, J; Consalvi, Valerio - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 1048-1058 - issn: 1742-464X - wos: WOS:000262666900014 (31) - scopus: 2-s2.0-58849132978 (39)
11573/360024 - 2008 -
The X-ray structure of N-methyltryptophan oxidase reveals the structural determinants of substrate specificity Ilari, Andrea; Bonamore, Alessandra; Stefano, Franceschini; Fiorillo, Annarita; Boffi, Alberto; Gianni, Colotti - 01a Articolo in rivista
rivista: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 2065-2075 - issn: 0887-3585 - wos: WOS:000255920600037 (23) - scopus: 2-s2.0-44349132154 (26)
11573/81932 - 2004 -
Crystallization and preliminary X-ray crystallographic analysis of the laminarinase endo-beta-1,3-glucanase from Pyrococcus furiosus. Ilari, Andrea; Angelaccio, Sebastiana; Fiorillo, Annarita; Florio, Rita; Consalvi, Valerio; Chiaraluce, Roberta - 01a Articolo in rivista
rivista: ACTA CRYSTALLOGRAPHICA. SECTION D, BIOLOGICAL CRYSTALLOGRAPHY (Blackwell Munksgaard:PO Box 2148, Periodicals Department, DK-1016 Copenhagen K Denmark:011 45 33 755913, EMAIL: agentservices@oxon.blackwellpublishing.com, INTERNET: http://www.blackwellmunksgaard.com, Fax: 011 45 77 333377) pp. 2394-2395 - issn: 0907-4449 - wos: WOS:000225360800026 (1) - scopus: 2-s2.0-21644464338 (1)