Research: New long-acting antiretroviral therapy impact on immune system in a HIV patient cohort
Current occupation
Since December 7, 2020 as physician in the Discipline of Infectious Diseases at UOC Infectious Diseases, S. Maria Goretti Hospital, AUSL of Latina.
Education
18/09/2017: Medicine and Surgery degree at Università degli Studi di Padova (110/110 cum laude); thesis title: “Implementation of clinical pathways for the development of an antibiotic stewardship program in pediatrics”.
28/02/2018: Licensed to practice as a doctor with registration with the Order of Doctors of Vicenza (registration number 6294).
02/11/2022: Infectious and Tropical disease Graduation at Università Sapienza di Roma (70/70 cum laude); thesis title: “Systemic and vaginal mucosal immune activation in women living with HIV on antiretroviral therapy”
03/11/2022 - ongoing: PhD in “Advances in infectious diseases, microbiology, legal medicine and public health sciences” , Università Sapienza di Roma
Clinical Experiences
March 2018 – October 2018: Substitution of General Doctor at ULSS Pedemontana Regione Veneto (Dr. B. Maino and Dr. P. Bernardi).
March 2018 – October 2018: Teacher of First Aid course at companies and high schools (Vicenza).
June 2018 – October 2018: Medical Guard at sporting events in collaboration with Italian Red Cross, Thiene (VI) Committee.
August 2018: Paramedic assistance as a volunteer at hospital facility coordinated and supported by Operation Mato Grosso Association, Zumbahua, Ecuador.
August 2013: Paramedic assistance as a volunteer at IIMC association's clinic and outpatient clinics in Kolkata, India, in collaboration with Project for People association in Milan and SISM (Segretariato Italiano Studenti Medicina).
Scientific Activity
Studies on natural immunity, monocyte function, and cytokine production during HIV infection, with a focus on the female population.
Studies on COVID-19, with focus on the cytokine-inflammatory response that develops during infection and focus on predisposing factors to worse outcomes.
Prevention and social Activity
Since 2018 participation in HIV infection prevention projects carried out on World AIDS Day, directed by the Infectious Diseases Unit of S. Maria Goretti Hospital in Latina.
Since 2021 activity with the FAST TRACK CITY project, joined by the City of Latina and the ASL of Latina; collaboration in Checkpoint creation with the aim of facilitating and making more usable the opportunity for counseling and performing HIV tests, free of charge and anonymously.
Collaboration in funded project
Project Ateneo 2020: “Role of innate immunity in SARS-CoV2 infection in a cohort of patients with COVID pneumonia: biomarkers and clinical correlates” (M.Lichtner)
Project Ateneo 2021: “Response markers and inflammatory pattern changes in a cohort of patients with SARS-Cov2 pneumonia undergoing treatment with immunomodulating drugs” (M.Lichtner)
Project funded by ViiV, in collaboration with Sapienza University of Rome: “Design of an electronic database in order to optimize treatment strategies in the HIV+ population (taking into consideration drug-economy and quality of life)”
Participation in Courses/ Trainings/ Congresses
May 2017: Basic Ultrasound course with SIUMB
21/11/2018: Conference “Masterclass in long – acting antibiotic therapy”, Rome
19/12/2018: Conference "Sixth workshop about chronic viral hepatitis", Latina
28/01/2019 – 29/01/2019: Congress "HIV and coinfections - 5th ICONA Founding meeting", Rome
22/02/2019: Conference "Serious infection in complicated patients", Rome
28/02/2019: Conference "Highlights about vertically infected", Modena
20/03/2019: Conference "HIV and HCV: customization and flexibility to guarantee QoL", Rome
02/04/2019: Conference "Emerging issues in HIV management", Rome
05/06/2019 – 07/06/2019: Congress "11th Italian Conference on AIDS and Antiviral Research", Milan
25/06/2019 – 26/06/2019: Conference "Strategie d'eccellenza per la gestione e l'approccio alla cura dell'epatite C HepCellence 2019”, Pisa
18/09/2019 – 19/09/2019: Arca Mentor School, Siena
26/09/2019 – 27/09/2019: Conference “ESCMID-ESGIE workshop- Study group for infections in the Elderly”, Rome
23/10/2019 – 25/10/2019: Migration medicine course, in collaboraation with Caritas Roma, Rome
24/11/2019 – 27/11/2019: XVIII national congress SIMIT, Palermo
11/12/2019: Conference "Un nuovo approccio in HIV: 2-drug regimen contenente dolutegravir", Verona
19/12/2019: Conference "Obiettivo eradicazione HCV e prevenzione HIV nel singolo e nella collettività", Latina
15/01/2020 – 17/01/2020: Conference “15th Residential Course on Clinical Pharmacology of Antiretrovirals”, Turin
13/12/2020- 16/12/2020: XIX national congress SIMIT
27/01/2021 – 28/01/2021: Course “I Farmaci dell’Emergenza, utilizzazione protocolli operativi”, Rome
13/09/2021 – 14/09/2021: Arca Mentor School, Firenze
21/10/2021 – 23/10/2021: Congress "13th Italian Conference on AIDS and Antiviral Research", Riccione
29/10/2021: Congress SIMIT Lazio: il ruolo dell’infettivologo nelle pandemie emergenti e riemergenti: la realtà laziale; Latina, as faculty.
02/12/2021: Conference “Si può migliorare l’outcome produttivo?”, Latina, as faculty
20/12/2021 – 21/12/2021: Conference “ICONA XT – Next generation educational program in HIV”, Milan
20/01/2022 – 21/01/2022: Course, American Heart Association
22/02/2022-23/02/2022: Congress "HIV and coinfections - 8th ICONA Founding meeting", Rome
18/03/2022: Conference “La tubercolosi oggi nel Lazio”, as faculty
06/04/2022-07/04/2022: Conference “Uptades and perspectives in HCV, HBV, HDV and COVID-19”, Rome
20/04/2022: Conference “Long Term success: il paziente HIV virologicamente soppresso”, Latina
28/04/2022 – 29/04/2022: Conference “ICONA XT – Next generation educational program in HIV”, Rome
20/05/2022-21/05/2022: Conference “European Experts Forum, Innovation in action: individualised HIV care is here”, London
31/05/2022: Conference “Screening dell’infezione tubercolare latente nel paziente fragile: linee guida e pratica clinica”, Latina, as faculty
23/06/2022-24/06/2022: Conference “ICONA XT – Next generation educational program in HIV”, Naples
26/09/2022- 27/09/2022: Conference “ICONA XT – Next generation educational program in HIV”, Florence
28/10/2022: Congress SIMIT Lazio – “Gestione clinica e ricerca scientifica in ambito infettivologico: le realtà del Lazio”, Rome, as faculty
09/02/2023 – 10/02/2023: Conference “ICONA XT – Next generation educational program in HIV”, Bologna
19/02/2023 – 22/02/2023: Conference on Retroviruses and Opportunistic Infections 2023, Seattle
Language Skills
Italian (Mother tongue)
English (B2), Spanish (A2)
Computer Skills
Microsoft Office (Word, Excel, PowerPoint); GraphPad Prism.
Publications
Real-life use of tocilizumab with or without corticosteroid in hospitalized patients with moderate-to-severe COVID-19 pneumonia. A retrospective cohort study.
Russo G.; Solimini A., Zuccalà P., Zingaropoli M. A., Carraro A., Pasculli P., Perri V., Marocco R., Kertusha B., Del Borgo C., Del Giudice E., Fondaco L., Tieghi T., D'Agostino C., Oliva A., Vullo V., Ciardi M. R., Mastroianni C. M., Lichtner M. - In: PLOS ONE. - ISSN 1932-6203. - 16:9(2021), pp. 1-20. [10.1371/journal.pone.0257376]
Increased sCD163 and sCD14 plasmatic levels and depletion of peripheral blood pro-inflammatory monocytes, myeloid and plasmacytoid dendritic cells in patients with severe COVID-19 pneumonia.
Zingaropoli, M. A.; Nijhawan, P.; Carraro, A.; Pasculli, P.; Zuccalà, P.; Perri, V.; Marocco, R.; Kertusha, B.; Siccardi, G.; Del Borgo, C.; Curtolo, A.; Ajassa, C.; Iannetta, M.; Ciardi, M. R.; Mastroianni, C. M.; Lichtner, M. - In: FRONTIERS IN IMMUNOLOGY. - ISSN 1664-3224. - 12(2021), pp. 1-12.
Role of tocilizumab in down regulating sCD163 plasmatic levels in a cohort of COVID-19 patients.
Marocco R, Carraro A, Zingaropoli MA, Nijhawan P, Tortellini E, Guardiani M, Mengoni F, Zuccalà P, Belvisi V, Kertusha B, Parente A, Del Borgo C, Vullo V, Ciardi MR, Mastroianni CM, Lichtner M. Front Immunol. 2022 Apr 4;13:871592. doi: 10.3389/fimmu.2022.871592. PMID: 35444637; PMCID: PMC9013773.
Is albumin predictor of mortality in COVID-19?
Violi F.; Cangemi R.; Romiti G. F.; Ceccarelli G.; Oliva A.; Alessandri F.; Pirro M.; Pignatelli P.; Lichtner M.; Carraro A. ; Cipollone F.; D'Ardes D.; Pugliese F.; Mastroianni C.M. - In: ANTIOXIDANTS & REDOX SIGNALING. - ISSN 1523-0864. - (2020).
Impact of SARS CoV-2 pandemic on carbapenemase-producing Klebsiella pneumoniae prevention and control programme. Convergent or divergent action?
Belvisi, V.; Del Borgo, C.; Vita, S.; Redaelli, P.; Dolce, P.; Pacella, D.; Kertusha, B.; Carraro, A.; Marocco, R.; De Masi, M.; Mastroianni, C.; Lichtner, M.; Cosentino, C.; Alibardi, L.; De Marchis, L.; Aiuti, M.; Carraturo, A.; Parrocchia, S.; Mecozzi, A.; De Meo, A.. - In: THE JOURNAL OF HOSPITAL INFECTION. - ISSN 0195-6701. - 109(2021), pp. 29-31.
Blood glucose and epicardial adipose tissue at the hospital admission as possible predictors for COVID-19 severity.
G. Guarisco; M. Fasolo; D. Capoccia; G. Morsello; A. Carraro; P. Zuccalà; R. Marocco; C. Del Borgo; G. Pelle; A. Iannarelli; E. Orlando; A. Spagnoli; I. Carbone; M. Lichtner; G. Iacobellis; F. Leonetti; the COVID-19 Latina Study Group, In: ENDOCRINE. - ISSN 1355-008X. - (2021). [10.1007/s12020-021-02925-5]
COVID-19 Severity and Androgen Receptor Polymorphism
Alessandra Buonacquisto, Anna Chiara Conflitti, Francesco Pallotti, Antonella Anzuini, Serena Bianchini, Luisa Caponecchia, Anna Carraro, Maria Rosa Ciardi, Fabiana Faja, Cristina Fiori, Daniele Gianfrilli, Andrea Lenzi, Miriam Lichtner, Claudio Maria Mastroianni, Patrizia Pasculli, Flavio Rizzo, Pietro Salacone, Annalisa Sebastianelli, Francesco Lombardo and Donatella Paoli. Biology, 2022, 11.7: 974.
Male reproductive health after 3 months from SARS CoV 2 infection: a multicentric study
Paoli D, Pallotti F, Anzuini A, Bianchini S, Caponecchia L, Carraro A, Ciardi MR, Faja F, Fiori C, Gianfrilli D, Lenzi A, Lichtner M, Marcucci I, Mastroianni CM, Nigro G, Pasculli P, Pozza C, Rizzo F, Salacone P, Sebastianelli A, Lombardo F. J Endocrinol Invest. 2022 Aug 9:1–13. doi: 10.1007/s40618-022-01887-3. Epub ahead of print. PMID: 35943723; PMCID: PMC9362397.
Longitudinal Assessment of Multiple Immunological and Inflammatory Parameters during Successful DAA Therapy in HCV Monoinfected and HIV/HCV Coinfected Subjects.
Zuccalà P, Latronico T, Marocco R, Savinelli S, Vita S, Mengoni F, Tieghi T, Borgo C, Kertusha B, Carraro A, D'Ettorre G, Vullo V, Mastroianni CM, Liuzzi GM, Lichtner M. Int J Mol Sci. 2022 Oct 8;23(19):11936. doi: 10.3390/ijms231911936. PMID: 36233234; PMCID: PMC9570033.
A case of primary central nervous system lymphoma in advanced naive HIV-infected patient: the role of antiviral agents
Carraro A, Belvisi V, Garattini S, Cacace S, Marocco R, Del Borgo C, Fiorentino F, Perrone S, Cimino G, Lichtner M. AIDS. 2022 Nov 1;36(13):1895-1896. doi: 10.1097/QAD.0000000000003298. PMID: 36172873
Quality of T-Cell Response to SARS-CoV-2 mRNA Vaccine in ART-Treated PLWH
Tortellini E, Zingaropoli MA, Mancarella G, Marocco R, Carraro A, Jamhour M, Barbato C, Guardiani M, Dominelli F, Pasculli P, Napoli A, Gaeta A, Mengoni F, Zuccalà P, Belvisi V, Kertusha B, Parente A, Del Borgo C, Vullo V, Ciardi MR, Mastroianni CM, Lichtner M, Latina Covid-Group. Int J Mol Sci. 2022 Nov 30;23(23):14988. doi: 10.3390/ijms232314988. PMID: 36499317; PMCID: PMC9741180.
Longitudinal Virological and Immunological Profile in a Case of Human Monkeypox Infection
Zingaropoli MA, Parente A, Kertusha B, Campagna R, Tieghi T, Garattini S, Marocco R, Carraro A, Tortellini E, Guardiani M, Dominelli F, Turriziani O, Ciardi MR, Mastroianni CM, Del Borgo C, Lichtner M. Open Forum Infect Dis. 2022 Nov 1;9(12):ofac569. doi: 10.1093/ofid/ofac569. PMID: 36474633; PMCID: PMC9716865.
Conference proceedings
Vaginal immunity and HPV infection in HIV infected women undergoing successful ART
Carraro A, Vita S, Marocco R, Kertusha B, Fondaco L, Pozzetto I, Ansaldo L, D’Achille M, Masci G, Mastroianni CM, Lichtner M, ICAR 2019, Milano. Poster
Immune inflammation markers in HCV subjects with low liver fibrosis undergoing DAAs treatment Kertusha B, Lichtner M, Mascia C, Nijhawan P, Marocco R, Vita S, Tieghi T, Pozzetto I, Fondaco L, Carraro A, Vetica A, Mercurio SM, Fabietti P, Del Borgo C, ICAR 2019, Milano. Oral Communication
CMV vaginal shedding in a cohort of HIV women under soppressive ART.
Vita S, Nijhawan P, Mascia C, Carraro A, Marocco R, Kertusha B, Fondaco L, Pozzetto I, Ansaldo L, Masci G, D’Achille M, Mercurio VS , Lichtner M, ICAR 2019. Poster
Dr Apollo chatbot: a digital contribution to the achievement of the “fourth 90” for people living with HIV.
Vita S, Marocco R, Morlino G, Palmacci V, Carraro A, Pozzetto I, Renzelli M, Del Borgo C, Mercurio VS, Mastroianni CM, Lichtner M, ICAR 2019, Milano, Poster
Is Sexual Health an issue to be addressed in HIV-1 infected and uninfected women?
Marocco R, Vita S, Carraro A, Kertusha B, Pozzetto I, Fondaco L, Ansaldo L, D’Achille M, Masci G, Mastroianni CM, M. Lichtner, ICAR 2019, Milano. Poster
Differences in Sexual Health among HIV infected and uninfected women of child-bearing age. Marocco R, Vita S, Carraro A, Kertusha B, Pozzetto I, Ansaldo L, Masci G, Gennaro V, CM Mastroianni, Lichtner M, 19th EACS 2019, Poster
Malattie infettive prevenibili e salute sessuale nella donna in età fertile: l’esperienza di un intervento dedicato.
Carraro A, Gennaro V, Marocco R, Kertusha B, Fondaco L, D’Achille M, Del Borgo C, Tieghi T, Ansaldo L, Masci G, Battaglia A, Ianiri P, Di Troia C, Ciardo, Marcucci I, Perugini A, Vita S, Lichtner M, SIMIT 2019, Palermo. Poster
Clinical experience of real life Dalbavancin use in acute skin and soft tissue infections: impact on hospitalization lenght.
Ketusha B, Gasperin A, Falsetto N, Marsiglia C, Marocco R, Vita S, Tieghi T, Fondaco L, Carraro A, Vetica A, Fabietti P, Mastroianni CM, Lichtner M, SIMIT 2019, Palermo. Poster
Impact of Biofire FilmArray meningitis/encephalitis in aseptic meningitis in children.
Carraro A, Cavani M, Borghesi L, Vita S, Ajassa C, ESPID 2020. Poster
HPV and bacterial vaginal infection impact on immune system in a cohort of HIV female population
Carraro A, Nijhawan P ,Vita S, Marocco R, Fondaco R, Kertusha B, Ansaldo A, Petrozza V, Cacciotti J, Renzelli M, Mastroianni CM, Lichtner M, 12th ICAR 2020. Poster
Marker di severità dell’infezione da Sars-CoV2: misurazione del grasso epicardico (EAT) e correlazione con gli outcome di malattia. Del Borgo C, Zuccalà P, Kertusha B, Carraro A, Pelle G, Iannarelli A, Fasolo M, Guarisco G, Morsello G, Capoccia D, Lichtner M, Leonetti F, SIMIT 2020. Oral communication
Infezione da Sars-CoV2 in una serie di pazienti con insufficienza renale cronica sottoposti a dialisi. Del Giudice E, Zuccalà P, Marocco R, Del Borgo C, De Masi M, Carraro A, Fabietti P, Vetica A, Rifici N, Cavarretta L, Fiederling B, Cioffi M, Lubrano R, Lichtner M, SIMIT 2020. Poster
Successful management of primary CNS EBV-related lymphoma in a late advanced naïve HIV
Carraro A, Cacace S, Garattini S, Perrone S, Marocco R, Del Borgo C, Belvisi V, Tieghi T, Jamhour M, Mancarella G, Parente A, Kertusha B, Fondaco L, Spoto C, Armocida D, Pompucci A, Cimino G, Lichtner M, 13th ICAR 2021, Poster
Role of Tocilizumab in down regulating the concentration of sCD163 in a cohort of
SARS-COV 2 infected patients with varying severity.
Nijhawan P, Carraro A, Zingaropoli MA, Zuccalà P, Perri V, Chichi E, Parente A, Marocco R, Kertusha B, Siccardi G, Del Borgo C, Belvisi V, Del Giudice E, Fondaco L, Carli S, Ajassa C, Mengoni M, Ciardi MR, Mastroianni CM, Lichtner M, 13th ICAR 2021, Oral Poster
Real life use of the anti-SARS CoV-2 monoclonal antibodies in the early phase of infection: planning, enrollment, administration and monitoring
C. Del Borgo, D. Caianiello, D. Di Trento, S. Garattini, G. Bagaglini, B. Kertusha, A. Carraro, A. Parente, P. Fabietti, O. D’Onofrio, S. Di Somma, G. Visconti, G. Bonanni, M. Lichtner. 13th ICAR 2021, Oral Poster
Towards “Fast-Track Cities” at the time of SARS-CoV2 pandemic: the combination of HIV blood test and nasopharyngeal swab on 1st December 2020 World AIDS Day.
G. Mancarella , V. Belvisi, M. Jamhour , R. Marocco, V.S. Mercurio, S. Cacace, P. Zuccalà , L. Fondaco, A. Carraro, M. D’Achille, V. Rossi , O. D’Onofrio, A.C. Petrillo, V. Vitale, M. Lichtner, 13th ICAR 2021, Poster
Characterization of virologically suppressed HIV infected individuals potential eligible to the long-acting combination of cabotegravir plus riplivirine: results from the Italian ARCA cohort
A. Cervo, A. Russo, D. Di Carlo, A. De Vito, L. Fabeni, S. D’Anna, L. Duca, A. Colpani, M. Fois, B. Zauli, G. Mancarella, A. Carraro, A. Bezenchek, A. Cozzi-Lepri, MM. Santoro, 14th ICAR 2022