11573/1696204 - 2023 -
NFE2L2 and STAT3 Converge on Common Targets to Promote Survival of Primary Lymphoma Cells Arena, Andrea; Di Crosta, Michele; Gonnella, Roberta; Zarrella, Roberta; Romeo, Maria Anele; Benedetti, Rossella; Gilardini Montani, Maria Saveria; Santarelli, Roberta; D’Orazi, Gabriella; Cirone, Mara - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:001036167700001 (0) - scopus: 2-s2.0-85166018355 (0)
11573/1696270 - 2023 -
JQ-1/bortezomib combination strongly impairs MM and PEL survival by inhibiting c-Myc and mTOR despite the activation of prosurvival mechanisms Arena, Andrea; Romeo, Maria Anele; Benedetti, Rossella; Gilardini Montani, Maria Saveria; Cirone, Mara - 01a Articolo in rivista
rivista: EXPERIMENTAL HEMATOLOGY (Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680) pp. 28-41 - issn: 0301-472X - wos: WOS:000957826000001 (2) - scopus: 2-s2.0-85147270519 (2)
11573/1696290 - 2023 -
NRF2 and STAT3: friends or foes in carcinogenesis? Arena, Andrea; Romeo, Maria Anele; Benedetti, Rossella; Gilardini Montani, Maria Saveria; Santarelli, Roberta; Gonnella, Roberta; D'orazi, Gabriella; Cirone, Mara - 01g Articolo di rassegna (Review)
rivista: DISCOVER ONCOLOGY ([New York]: Springer, 2021-) pp. 37- - issn: 2730-6011 - wos: WOS:000961857300002 (4) - scopus: 2-s2.0-85153108305 (4)
11573/1671685 - 2023 -
Different outcome of targeting ERN1/IRE1 alpha and EIF2AK3/PERK in NSG mice engrafted with primary effusion lymphoma Arena, Andrea; Romeo, Maria Anele; Focaccetti, Chiara; Anastasiadou, Eleni; Trivedi, Pankaj; Cifaldi, Loredana; Gilardini Montani, Maria Saveria; Benedetti, Rossella; Santarelli, Roberta; Gonnella, Roberta; Benvenuto, Monica; Marchese, Cinzia; Masuelli, Laura; Bei, Roberto; Cirone, Mara - 01f Lettera, Nota
rivista: BRITISH JOURNAL OF HAEMATOLOGY (Oxford]: [Blackwell Science].) pp. 1-4 - issn: 1365-2141 - wos: WOS:000935692900001 (1) - scopus: 2-s2.0-85148023663 (0)
11573/1691548 - 2023 -
The inhibition of IRE1alpha/XBP1 axis prevents EBV-driven lymphomagenesis in NSG mice Arena, Andrea; Romeo, Maria Anele; Po, Agnese; Benedetti, Rossella; Gilardini Montani, Maria Saveria; Gonnella, Roberta; Santarelli, Roberta; Gaeta, Aurelia; De Smaele, Enrico; Cirone, Mara - 01a Articolo in rivista
rivista: MICROBIOLOGY SPECTRUM (Washington, DC : ASM Press, 2014-) pp. 1-6 - issn: 2165-0497 - wos: WOS:001095474200001 (0) - scopus: 2-s2.0-85180012834 (0)
11573/1696206 - 2023 -
HSPs/STAT3 Interplay Sustains DDR and Promotes Cytokine Release by Primary Effusion Lymphoma Cells Gonnella, Roberta; Arena, Andrea; Zarrella, Roberta; Gilardini Montani, Maria Saveria; Santarelli, Roberta; Cirone, Mara - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000939181000001 (4) - scopus: 2-s2.0-85149335889 (2)
11573/1696211 - 2023 -
HSP110 Inhibition in Primary Effusion Lymphoma Cells. One Molecule, Many Pro-Survival Targets Gonnella, Roberta; Zarrella, Roberta; Di Crosta, Michele; Benedetti, Rossella; Arena, Andrea; Santarelli, Roberta; Gilardini Montani, Maria Saveria; D’Orazi, Gabriella; Cirone, Mara - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. 1-12 - issn: 2072-6694 - wos: WOS:001115967900001 (0) - scopus: 2-s2.0-85178926403 (0)
11573/1696294 - 2023 -
Acetylation increases expression, interaction with TRAPPC4 and surface localization of PD-L1 Romeo, Maria Anele; Gilardini Montani, Maria Saveria; Santarelli, Roberta; Benedetti, Rossella; Arena, Andrea; Cirone, Mara - 01a Articolo in rivista
rivista: DISCOVER ONCOLOGY ([New York]: Springer, 2021-) pp. 152- - issn: 2730-6011 - wos: WOS:001052800600002 (0) - scopus: 2-s2.0-85168487188 (0)
11573/1696302 - 2023 -
EBV infection of primary colonic epithelial cells causes inflammation, DDR and autophagy dysregulation, effects that may predispose to IBD and carcinogenesis Santarelli, Roberta; Evangelista, Lorenzo; Pompili, Chiara; Lo Presti, Salvatore; Rossi, Alberto; Arena, Andrea; Gaeta, Aurelia; Gonnella, Roberta; Gilardini Montani, Maria Saveria; Cirone, Mara - 01a Articolo in rivista
rivista: VIRUS RESEARCH (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1-11 - issn: 0168-1702 - wos: WOS:001098684800001 (0) - scopus: 2-s2.0-85173243375 (0)
11573/1587456 - 2022 -
DNA damage triggers an interplay between wtp53 and c-Myc affecting lymphoma cell proliferation and Kaposi sarcoma herpesvirus replication Arena, A.; Gilardini Montani, M. S.; Romeo, M. A.; Benedetti, R.; Gaeta, A.; Cirone, M. - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1-11 - issn: 0167-4889 - wos: WOS:000717326400005 (15) - scopus: 2-s2.0-85118539605 (15)
11573/1640499 - 2022 -
Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma Cells Arena, A.; Romeo, M. A.; Benedetti, R.; Gilardini Montani, M. S.; Cirone, M. - 01a Articolo in rivista
rivista: BIOMEDICINES (Basel : MDPI) pp. 1-12 - issn: 2227-9059 - wos: WOS:000786755100001 (9) - scopus: 2-s2.0-85127699313 (9)
11573/1640511 - 2022 -
The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells Arena, A.; Romeo, M. A.; Benedetti, R.; Gilardini Montani, M. S.; Cirone, M. - 01a Articolo in rivista
rivista: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 19-25 - issn: 0006-291X - wos: WOS:000878132700004 (2) - scopus: 2-s2.0-85129320111 (2)
11573/1659741 - 2022 -
Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP. A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas Benedetti, R.; Arena, A.; Romeo, M. A.; Gilardini Montani, M. S.; Gonnella, R.; Santarelli, R.; Trivedi, P.; Cirone, M. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 1-13 - issn: 1661-6596 - wos: WOS:000846661400001 (3) - scopus: 2-s2.0-85137722317 (4)
11573/1671667 - 2022 -
ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress Benedetti, Rossella; Romeo, Maria Anele; Arena, Andrea; Gilardini Montani, Maria Saveria; Di Renzo, Livia; D'orazi, Gabriella; Cirone, Mara - 01a Articolo in rivista
rivista: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. 1-12 - issn: 2058-7716 - wos: WOS:000815638500001 (9) - scopus: 2-s2.0-85132944532 (11)
11573/1640535 - 2022 -
p62/SQSTM1 promotes mitophagy and activates the NRF2-mediated antioxidant and anti-inflammatory response restraining EBV-driven B lymphocyte proliferation Gilardini Montani, Maria Saveria; Tarquini, Greta; Santarelli, Roberta; Gonnella, Roberta; Romeo, Maria Anele; Benedetti, Rossella; Arena, Andrea; Faggioni, Alberto; Cirone, Mara - 01a Articolo in rivista
rivista: CARCINOGENESIS (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 277-287 - issn: 0143-3334 - wos: WOS:000756810200001 (9) - scopus: 2-s2.0-85129269602 (11)
11573/1614983 - 2022 -
VPA and TSA Interrupt the Interplay between mutp53 and HSP70, Leading to CHK1 and RAD51 Down-Regulation and Sensitizing Pancreatic Cancer Cells to AZD2461 PARP Inhibitor Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Arena, A.; D'orazi, G.; Cirone, M. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 1-14 - issn: 1661-6596 - wos: WOS:000772044700001 (11) - scopus: 2-s2.0-85124907434 (12)
11573/1627726 - 2022 -
The dysregulation of autophagy and ER stress induced by HHV-6A infection activates pro-inflammatory pathways and promotes the release of inflammatory cytokines and cathepsin S by CNS cells Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Arena, A.; Gaeta, A.; Cirone, M. - 01a Articolo in rivista
rivista: VIRUS RESEARCH (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1-9 - issn: 0168-1702 - wos: WOS:000777670800001 (2) - scopus: 2-s2.0-85125851175 (2)
11573/1659739 - 2022 -
c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway Romeo, Maria Anele; Gilardini Montani, Maria Saveria; Arena, Andrea; Benedetti, Rossella; D’Orazi, Gabriella; Cirone, Mara - 01a Articolo in rivista
rivista: BIOMEDICINES (Basel : MDPI) pp. 1-13 - issn: 2227-9059 - wos: WOS:000872167900001 (1) - scopus: 2-s2.0-85140649876 (1)
11573/1587474 - 2021 -
New insights into curcumin-and resveratrol-mediated anti-cancer effects Arena, A.; Romeo, M. A.; Benedetti, R.; Masuelli, L.; Bei, R.; Gilardini Montani, M. S.; Cirone, M. - 01a Articolo in rivista
rivista: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. 1-12 - issn: 1424-8247 - wos: WOS:000727825100001 (25) - scopus: 2-s2.0-85117921973 (27)
11573/1577796 - 2021 -
Role of upr sensor activation in cell death–survival decision of colon cancer cells stressed by dpe treatment Benedetti, R.; Gilardini Montani, M. S.; Romeo, M. A.; Arena, A.; Santarelli, R.; D'orazi, G.; Cirone, M. - 01a Articolo in rivista
rivista: BIOMEDICINES (Basel : MDPI) pp. 1-14 - issn: 2227-9059 - wos: WOS:000699083100001 (10) - scopus: 2-s2.0-85115785094 (10)
11573/1542820 - 2021 -
p53-R273H Sustains ROS, Pro-Inflammatory Cytokine Release and mTOR Activation While Reducing Autophagy, Mitophagy and UCP2 Expression, Effects Prevented by wtp53 Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Arena, A.; D'orazi, G.; Cirone, M. - 01a Articolo in rivista
rivista: BIOMOLECULES (Basel: MDPI) pp. 1-14 - issn: 2218-273X - wos: WOS:000633432800001 (5) - scopus: 2-s2.0-85101254797 (4)
11573/1581319 - 2021 -
Anticancer effect of AZD2461 PARP inhibitor against colon cancer cells carrying wt or dysfunctional p53 Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Arena, A.; Maretto, M.; Bassetti, E.; Caiazzo, R.; D'orazi, G.; Cirone, M. - 01a Articolo in rivista
rivista: EXPERIMENTAL CELL RESEARCH (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 1-9 - issn: 0014-4827 - wos: WOS:000708776900014 (10) - scopus: 2-s2.0-85116884973 (9)
11573/1446209 - 2020 -
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases Genovese, I.; Giamogante, F.; Barazzuol, L.; Battista, T.; Fiorillo, A.; Vicario, M.; D'alessandro, G.; Cipriani, R.; Limatola, C.; Rossi, D.; Sorrentino, V.; Poser, E.; Mosca, L.; Squitieri, F.; Perluigi, M.; Arena, A.; Van Petegem, F.; Tito, C.; Fazi, F.; Giorgi, C.; Cali, T.; Ilari, A.; Colotti, G. - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. 1-18 - issn: 2041-4889 - wos: WOS:000581611700003 (24) - scopus: 2-s2.0-85092570946 (24)
11573/1244127 - 2019 -
Reduced biliverdin reductase-a levels are associated with early alterations of insulin signaling in obesity Cimini, Flavia Agata; Arena, Andrea; Barchetta, Ilaria; Tramutola, Antonella; Ceccarelli, Valentina; Lanzillotta, Chiara; Fontana, Mario; Bertoccini, Laura; Leonetti, Frida; Capoccia, Danila; Silecchia, Gianfranco; Di Cristofano, Claudio; Chiappetta, Caterina; Di Domenico, Fabio; Baroni, Marco Giorgio; Perluigi, Marzia; Cavallo, Maria Gisella; Barone, Eugenio - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0925-4439 - wos: WOS:000468708200039 (27) - scopus: 2-s2.0-85062273097 (29)
11573/1273664 - 2019 -
Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome Di Domenico, Fabio; Tramutola, Antonella; Barone, Eugenio; Lanzillotta, Chiara; Defever, Olivia; Arena, Andrea; Zuliani, Ilaria; Foppoli, Cesira; Iavarone, Federica; Vincenzoni, Federica; Castagnola, Massimo; Butterfield, D Allan; Perluigi, Marzia - 01a Articolo in rivista
rivista: REDOX BIOLOGY (Amsterdam : Elsevier) pp. 101162- - issn: 2213-2317 - wos: WOS:000498848200015 (41) - scopus: 2-s2.0-85062690014 (46)
11573/1244121 - 2019 -
Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease Sharma, Nidhi; Tramutola, Antonella; Lanzillotta, Chiara; Arena, Andrea; Blarzino, Carla; Cassano, Tommaso; Butterfield, D. Allan; Di Domenico, Fabio; Perluigi, Marzia; Barone, Eugenio - 01a Articolo in rivista
rivista: NEUROBIOLOGY OF DISEASE (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 176-189 - issn: 0969-9961 - wos: WOS:000461406000017 (42) - scopus: 2-s2.0-85061254683 (44)
11573/1118370 - 2018 -
Disturbance of redox homeostasis in down syndrome: role of iron dysmetabolism Barone, Eugenio; Arena, Andrea; Head, Elizabeth; Butterfield, D. Allan; Perluigi, Marzia - 01a Articolo in rivista
rivista: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 84-93 - issn: 0891-5849 - wos: WOS:000418889700010 (32) - scopus: 2-s2.0-85023755307 (39)
11573/1199021 - 2018 -
Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome Tramutola, Antonella; Lanzillotta, Chiara; Barone, Eugenio; Arena, Andrea; Zuliani, Ilaria; Mosca, Luciana; Blarzino, Carla; Butterfield, D. Allan; Perluigi, Marzia; Di Domenico, Fabio - 01a Articolo in rivista
rivista: TRANSLATIONAL NEURODEGENERATION (London : BioMed Central) pp. 1-28 - issn: 2047-9158 - wos: WOS:000449479100001 (65) - scopus: 2-s2.0-85056084092 (72)
11573/935436 - 2017 -
Polyubiquitinylation profile in down syndrome brain before and after the development of Alzheimer neuropathology Tramutola, Antonella; Di Domenico, Fabio; Barone, Eugenio; Arena, Andrea; Giorgi, Alessandra; Di Francesco, Laura; Schinina', Maria Eugenia; Coccia, Raffaella; Head, Elizabeth; Butterfield, D. Allan; Perluigi, Marzia - 01a Articolo in rivista
rivista: ANTIOXIDANTS & REDOX SIGNALING (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 280-298 - issn: 1523-0864 - wos: WOS:000394334400002 (32) - scopus: 2-s2.0-85013434336 (36)
11573/846243 - 2016 -
Impairment of biliverdin reductase-a promotes brain insulin resistance in Alzheimer disease: a new paradigm Barone, Eugenio; Di Domenico, Fabio; Cassano, Tommaso; Arena, Andrea; Tramutola, Antonella; Lavecchia, Michele Angelo; Coccia, Raffaella; Butterfield, D. Allan; Perluigi, Marzia - 01a Articolo in rivista
rivista: FREE RADICAL BIOLOGY & MEDICINE (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 127-142 - issn: 0891-5849 - wos: WOS:000370181400012 (86) - scopus: 2-s2.0-84950335909 (91)
11573/840612 - 2016 -
Increased mammalian target of rapamycin signaling contributes to the accumulation of protein oxidative damage in a mouse model of down's syndrome Tramutola, Antonella; Lanzillotta, Chiara; Arena, Andrea; Barone, Eugenio; Perluigi, Marzia; Di Domenico, Fabio - 01a Articolo in rivista
rivista: NEURODEGENERATIVE DISEASES (Basel [etc.]: S. Karger 2004-) pp. 62-68 - issn: 1660-2854 - wos: WOS:000369778000010 (33) - scopus: 2-s2.0-84958063630 (34)
11573/867882 - 2016 -
Activation of p53 in down syndrome and in the ts65dn mouse brain is associated with a pro-apoptotic phenotype Tramutola, Antonella; Pupo, Gilda; Di Domenico, Fabio; Barone, Eugenio; Arena, Andrea; Lanzillotta, Chiara; Broekaart, Diede; Blarzino, Carla; Head, Elizabeth; Butterfield, D. Allan; Perluigi, Marzia - 01a Articolo in rivista
rivista: JOURNAL OF ALZHEIMER'S DISEASE (Netherlands: IOS Press) pp. 359-71-371 - issn: 1387-2877 - wos: WOS:000375008500030 (24) - scopus: 2-s2.0-84973143959 (28)
11573/670416 - 2015 -
Bach1 overexpression in down syndrome correlates with the alteration of the ho-1/bvr-a system: insights for transition to Alzheimer's disease Di Domenico, Fabio; Pupo, Gilda; Mancuso, C; Barone, Eugenio; Paolini, F; Arena, Andrea; Blarzino, Carla; Schmitt, Fa; Head, E; Butterfield, Da; Perluigi, Marzia - 01a Articolo in rivista
rivista: JOURNAL OF ALZHEIMER'S DISEASE (Netherlands: IOS Press) pp. - - issn: 1387-2877 - wos: WOS:000350001000007 (47) - scopus: 2-s2.0-84923270517 (50)