Research: SINGLE CELL APPROACH TO IDENTIFY NOVEL MARKERS WITH POTENTIAL CLINICAL SIGNIFICANCE FOR MONITORING THYMIC FUNCTION
WORKPLACE: OPBG San Paolo headquarters - Ferdinando Baldelli Avenue, 38
SUPERVISOR/S: Dr. Enrico Velardi
PREVIOUS RESEARCH EXPERIENCE:
- 03/2024-Present Research Fellowship Bambino Gesù Children's Hospital department of Onco-Hematology and Cell and Gene Therapy.
- 03/2023-11/2023 Master's Thesis AOUS Policlinico le Scotte Siena department of Hematology. Thesis Title: Cyclin D1 overexpression and its correlation with treatment and survival of Multiple Myeloma patients with t(11;14) translocation.
- 02/2021-06/2021 Bachelor's Thesis University of Pisa Department of Biochemistry. Thesis Title: Characterization of the inhibitory activity of synthetic molecules against the enzyme AKR1B1.
CAREER:
- 11/2024-Present PhD in Molecular Medicine La Sapienza at Bambino Gesù Children's Hospital Department of Oncology-Hematology and Gene Therapy.
- 10/2021-12/2023 Master's degree in Medical Biotechnologies University of Siena. Graduation grade 110/110 cum laude.
- 09/2018-09/2021 Bachelor's degree in Biotechnology University of Pisa. Graduation grade 110/110 cum laude.
SKILLS:
Production of human recombinant enzyme by transformation and recombinant DNA, purification of such enzyme by column chromatography, spectrophotometric assay of enzyme activity.
Blood cell culture, separation/isolation of clonal CD138+ plasma cells, FISH analysis with Genikon software, karyotype analysis with Genikon software, immunophenotypic evaluation of Bcl2.
Jurkat and ANV cell culture, isolation of PBMCs, enrichment with magnetic beads, FACS panel design, FlowJo analysis, DNA/RNA extraction, Rt-PC.
LANGUAGES:
Italian (Mother tongue), English (Fluent - B2 )