Phd in ACCELERATOR PHYSICS

email: alessio.sarti@uniroma1.it
phone:

Curriculum Vitae
Researcher unique identifier: orcid.org/0000-0001-5419-7951
Web site: http://arpg-serv.ing2.uniroma1.it/sarti


Current/past positions:
2018- : Associated professor at the University of Rome “Sapienza”
2010-2018 : Researcher at the University of Rome “Sapienza”
2005-2010 : Research associate position at Laboratori Nazionali di Frascati (LNF) of Istituto Nazionale di Fisica Nucleare (INFN)
2004-2005 : Postdoctoral grant at the University of Rome “Sapienza”
Education:
2001-2003 : Ph.D. in Physics, University of Ferrara (supervisor Prof. L. Piemontese)
1996-2000 : Master Degree in Physics, full marks, University of Rome La Sapienza (supervisor Prof. F. Ferroni)

International Collaborations:
2017- : GSI, Darmstadt; Installation and commissioning of the FOOT experiment, data collection and data analysis
2014- : HIT, Heidelberg; Measurements of secondary radiation production from light ion beams of therapeutic energy (as part of ULICE European project).
2011-2016: GSI, Darmstadt; Installation and commissioning of the FIRST experiment, data collection and data analysis (RDH – INFN project).
2010- : CERN, Geneva; LHCb experiment data collection and data analysis (member of the rare decays working group and Bd,s rare decays into two muons task force), Muon System Expert.
2006-2009: CERN, Geneva; INFN - LNF team member of the LHCb muon system installation and commissioning task force for two years.
2002 : SLAC, Stanford, California; Run Quality Manager for the BaBar collaboration

Patents: in 2013 I have deposed a granted patent request (PCT/IT2014/000025) for a “Beta radiation probe for the intra-operative identification of tumour residuals”. Such request has been registered as a request for a European patent (Patent number EP2951612: INTRAOPERATIVE DETECTION OF TUMOR RESIDUES USING BETA- RADIATION AND CORRESPONDING PROBES) and for a USA patent (Patent number US20150359499)

Scientific Charges:
2018-2019: Member of the Sapienza Research Commission Panel for the funding of internal research projects (11 M€ budget)
2017- : Member of the doctorate collage board in Accelerator Physics at the Sapienza Rome university
2017- : Coordinator of the 'DoseProfiler' project dedicated to the online monitoring of carbon ion treatments in Particle Therapy at the CNAO centre
2011-2016: Physics Analysis Coordinator of the FIRST collaboration (GSI, Darmstadt)
2011- : Analysis reviewer appointed by the LHCb collaboration
2002 : Run quality manager of the BaBar collaboration

Supervision Activities and Teaching:
2005 - 2009: I held the “Physics” course in the 2nd Medicine Faculty of “La Sapienza” Rome University
2011- : I’m holding the “Physics I - Mechanics and Thermodynamics” course, in Civil and Industrial Engineering Faculty of “La Sapienza” Rome university
Career supervision: I am currently supervising several postdoc researchers and a PhD students working on applied physics projects (Centro Fermi grants, FOOT collaboration) and a PhD student within the LHCb collaboration. I already supervised more than 10 graduate students whose research was related to the applied physics field both in the Physics and Bio-Medical engineering courses. As physics analysis coordinator of the FIRST collaboration, I have supervised the work of more than 15 researchers from different countries and research institutes and the work of several PhD students from Germany (GSI) and Italy (Turin, Catania, Rome).

Society memberberships, Awards and Honors:
2019 - : Associate of INFN, in Roma1 section, with research contract currently related to the LHCb (HEP) and FOOT (Applied Physics) collaborations activities.
2010 - 2018: Associate of INFN, in Laboratori Nazionali di Frascati centre, with research contract currently related to the LHCb (HEP) and RDH (Applied Physics) collaborations activities.
2'16 - : Member of the FOOT collaboration [https://web.infn.it/f00t/index.php/it/].
2015 - 2019: Associate of Centro Fermi, a research institute devoted to multidisciplinary studies
2011 - : Member of the ARPG collaboration [http://arpg-serv.ing2.uniroma1.it/arpg-site/].
2004 - : Member of the LHCb collaboration [http://lhcb.web.cern.ch/lhcb/].
1996 : won the “Enrico Persico” Fellowship of the “Accademia Nazionale dei Lincei”

Research information:
I started my career in the field of HEP in the BaBar (2000-2004) and LHCb (2004-) collaborations gaining an invaluable experience in all the difference experimental aspects of the High Energy Physics field working with some of the worldwide most renowned scientist and stimulating research environments (SLAC - Stanford, CERN - Geneva, LNF - Frascati). The HEP research was dedicated to the study of rare leptonic and semileptonic B-decays and in this field I was able to become one of the main actors of the Bs to mumu search that lead to the best world results in this search from the LHCb experiment in the ten years window btw 2010 and 2020.

Since 2009 I had differentiated the scope of my research, in order to pursue the application of the HEP techniques to the medical field. I started (participated / organized / lead) a set of experimental measurements (@FIRST coll. GSI, 2011; @ARPG coll. LNS 2010, GSI 2012, CNAO 2013, HIT 2014) aiming for a radical reduction of the experimental uncertainty on the interactions of the beam particles used for charged particle therapy applications with matter (and hence, patient tissues). In 2013 “La Sapienza” funded my own research project devoted to the calibration of a dose monitoring prototype device. And since then I was involved in applied physics projects related to the planning and monitoring of Particle Therapy (PT) treatments.

I'm leading the Dose Profiler project since 2017, with the aim of develop a novel technique for the monitoring of 12C ions PT treatments detecting secondary charged fragments. The detector we built was tested at CNAO and finally underwent a clinical trial (started in 2019) to assess the technique performance in a real clinical case scenario. Ten patients have been monitored so far, and the promising results, obtained for the very first time ever monitoring a patient, were recently published on Scientific Reports from Nature.

Beside the Dose Profiler I am currently actively involved in projects related to the study of the RBE in proton treatments, monitoring of neutrons produced in PT by means of an active tracker, monitoring of proton treatments by means of prompt gamma detection and planning of radiotherapy treatments performed using a novel technique that involves high energy electrons exploiting a high dose rate (FLASH effect).

Funding Information:
In 2013 I obtained and directed the “Calibration of a novel technique for dose monitoring in Hadrontherapy”, project funded by the Università di Roma “La Sapienza” for 1 year (36k€).
In 2011-2014 I successfully participated to two Centro Fermi projects (400 k€ grant total) and to the INSIDE PRIN project (1M€ grant) on hadrontherapy related monitoring techniques. My contribution was determinant for the projects success: I had a major role in writing the proposals, coordinating the monitoring work packages and the work of the involved students and Ph.D. researchers.
In 2013-2015 I contributed to the “Imaging and cell tracking” Work Package (520 k€ grant), part of the “Novel strategies for the imaging and treatment of brain tumors through targeting cancer stem cell-specific signaling pathways”, that was funded by Italian Institute of Technology (IIT), 9 M€ grant.
In 2015 – 2018, I contributed directly to the writing to the funded project “MOnitor for Neutron Dose in hadrOntherapy” (MONDO), SIR of the Centro Fermi (550k€ grant total).


All the aforementioned projects are related to particle physics techniques applied to the particle therapy and applied medicine field.

Scientific production:
I have authored, as of Jan 2021, 747 publications in refereed international journals [source is scopus], 30k total citations with an h index of 83; out of those, more than 50 are relative to the applied physics field and have been published after 2012.