ALESSANDRO ZENNARO

Dottore di ricerca

ciclo: XXXII

Titolo della tesi: About the cryptic prophage contribution to the OMV production of E.coli. Influences of intestinal metabolites on the virulence of Shigella

My PhD thesis was focused on two main projects. In the first we investigated the relationship between the lytic form of the DLP12 prophage, composed of the four SRRz/Rz1 genes, and the production of outer membrane vesicles (OMVs). Moreover, we functionally identified a new promoter responsible for lytic module transcription and provide evidence about the FIS involvement in its regulation. Finally, we studied the role of environmental stress in the modulation of the lytic module expression. Altogether, the results obtained provide a clearer picture of the functional and regulatory properties of the lytic module of DLP12 prophage confirming the genetic contribution of prophage and their functional modules to the evolution of bacteria. In the second we investigated how several molecules product by the microbiota or by the intestinal mucosa (short-chain fatty acids, epinephrine and vitamin B12) influence the virulence of a well-adapted human enteropathogen, Shigella.

Produzione scientifica

11573/1723656 - 2023 - Adjuvant capecitabine in triple negative breast cancer patients with residual disease after neoadjuvant treatment: real-world evidence from CaRe, a multicentric, observational study

Di Lisa, Francesca Sofia; Krasniqi, Eriseld; Pizzuti, Laura; Barba, Maddalena; Cannita, Katia; De Giorgi, Ugo; Borella, Fulvio; Foglietta, Jennifer; Cariello, Anna; Ferro, Antonella; Picardo, Elisa; Mitidieri, Marco; Sini, Valentina; Stani, Simonetta; Tonini, Giuseppe; Santini, Daniele; La Verde, Nicla; Gambaro, Anna Rita; Grassadonia, Antonino; Tinari, Nicola; Garrone, Ornella; Sarobba, Giuseppina; Livi, Lorenzo; Meattini, Icro; D'auria, Giuliana; Vergati, Matteo; Gamucci, Teresa; Pistelli, Mirco; Berardi, Rossana; Risi, Emanuela; Giotta, Francesco; Lorusso, Vito; Rinaldi, Lucia; Artale, Salvatore; Cazzaniga, Marina Elena; Zustovich, Fable; Cappuzzo, Federico; Landi, Lorenza; Torrisi, Rosalba; Scagnoli, Simone; Botticelli, Andrea; Michelotti, Andrea; Fratini, Beatrice; Saltarelli, Rosa; Paris, Ida; Muratore, Margherita; Cassano, Alessandra; Gianni, Lorenzo; Gaspari, Valeria; Veltri, Enzo Maria; Zoratto, Federica; Fiorio, Elena; Fabbri, Maria Agnese; Mazzotta, Marco; Ruggeri, Enzo Maria; Pedersini, Rebecca; Valerio, Maria Rosaria; Filomeno, Lorena; Minelli, Mauro; Scavina, Paola; Raffaele, Mimma; Astone, Antonio; De Vita, Roy; Pozzi, Marcello; Riccardi, Ferdinando; Greco, Filippo; Moscetti, Luca; Giordano, Monica; Maugeri-Saccà, Marcello; Zennaro, Alessandro; Botti, Claudio; Pelle, Fabio; Cappelli, Sonia; Cavicchi, Flavia; Vizza, Enrico; Sanguineti, Giuseppe; Tomao, Federica; Cortesi, Enrico; Marchetti, Paolo; Tomao, Silverio; Speranza, Iolanda; Sperduti, Isabella; Ciliberto, Gennaro; Vici, Patrizia - 01a Articolo in rivista

rivista: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. - - issn: 2234-943X - wos: WOS:000997057100001 (2) - scopus: 2-s2.0-85161078688 (2)

11573/1311714 - 2019 - The Varied Role of Efflux Pumps of the MFS Family in the Interplay of Bacteria with Animal and Plant Cells

Pasqua, Martina; Grossi, Milena; Zennaro, Alessandro; Fanelli, Giulia; Micheli, Gioacchino; Barras, Frederic; Colonna, Bianca; Prosseda, Gianni - 01a Articolo in rivista

rivista: MICROORGANISMS (Basel: MDPI) pp. - - issn: 2076-2607 - wos: WOS:000489131300012 (62) - scopus: 2-s2.0-85074357294 (70)

11573/1100417 - 2013 - DIAGNOSTIC VALIDITY STATISTICS IN MCMI III APPLIED TO AN ITALIAN SAMPLE

Zennaro, Alessandro; Ferracuti, S.; Lang, M.; Roccato, G.; Roma, P.; Sanavio, E.; Horn, S. - 01a Articolo in rivista

rivista: BOLLETTINO DI PSICOLOGIA APPLICATA (Firenze : Giunti O. S. Organizzazioni speciali, u014- Firenze : O.S. Organizzazioni Speciali) pp. - - issn: 0006-6761 - wos: (0) - scopus: (0)